Produção Nacional
Revisado por pares
Letícia Cavassini Torquato, Eduardo Antonio Chelin Suárez, Daniella Viscensotto Bernardo, Isis Luzcybel Ribeiro Pinto, Ludmilla Oliveira Mantovani, Thiago Igor Lemes Silva, Maria Aparecida Neves Jardini, Mauro Pedrine Santamaría, Andréa Carvalho De Marco,
Tópico(s): Endodontics and Root Canal Treatments
2021 - Springer Science+Business Media | Lasers in Medical Science
Produção Nacional
Revisado por pares
Rafael Thiago Luiz Ferreira, Igor Cardoso Amatte, Thiago Assis Dutra, Daniel Bürger,
The objective of this work is the mechanical characterization of materials produced by 3D printing based on fused filament fabrication (FFF, analogous to FDM®). The materials chosen are a polylactic acid (PLA) and a PLA reinforced with short carbon fibers in a weight fraction of 15% (PLA+CF). In view of the FFF nature, which produces specimens layer by layer and following predefined orientations, the main assumption considered is that the materials behave like laminates formed by orthotropic layers. ...
Tópico(s): biodegradable polymer synthesis and properties
2017 - Elsevier BV | Composites Part B Engineering
Produção Nacional
Revisado por pares
Eduardo Vieira, Thiago Guimarães, Igor Vilela Faquini, Jose L. Silva, Tammy Saboia, Rodrigo V. C. L. Andrade, Thaís L. Gemir, Valesca C. Neri, Nivaldo S. Almeida, Hildo Rocha Cirne Azevedo‐Filho,
OBJECTIVE Decompressive craniectomy (DC) is a widely used procedure in neurosurgery; however, few studies focus on the best surgical technique for the procedure. The authors’ objective was to conduct a prospective randomized controlled trial comparing 2 techniques for performing DC: with watertight duraplasty and without watertight duraplasty (rapid-closure DC). METHODS The study population comprised patients ranging in age from 18 to 60 years who were admitted to the Neurotrauma Service of the Hospital ...
Tópico(s): Neurosurgical Procedures and Complications
2017 - American Association of Neurological Surgeons | Journal of neurosurgery
Produção Nacional
Revisado por pares
José Ângelo Lauletta Lindoso, Mirella Alves Cunha, Igor Thiago Queiroz, Carlos Henrique Valente Moreira,
Leishmaniasis - human immunodeficiency virus (HIV) coinfection can manifest itself as tegumentary or visceral leishmaniasis. Almost 35 countries have reported autochthonous coinfections. Visceral leishmaniasis is more frequently described. However, usual and unusual manifestations of tegumentary leishmaniasis have been reported mainly in the Americas, but the real prevalence of Leishmania infection in HIV-infected patients is not clear. Regarding the clinical manifestations, there are some reports ...
Tópico(s): Research on Leishmaniasis Studies
2016 - Dove Medical Press | HIV/AIDS - Research and Palliative Care
Produção Nacional
Revisado por pares
José Ângelo Lauletta Lindoso, Jackson Maurício Lopes Costa, Igor Thiago Queiroz, Hiro Goto,
Keywords: tegumentary, visceral, therapy, HIV
Tópico(s): Trypanosoma species research and implications
2012 - Dove Medical Press | Research and Reports in Tropical Medicine
Produção Nacional
Revisado por pares
Maria Carmen Arroyo Sanchez, Beatriz Julieta Celeste, José Ângelo Lauletta Lindoso, Mahyumi Fujimori, Roque Pacheco de Almeida, Carlos Magno Castelo Branco Fortaleza, Angelita Fernandes Druzian, Ana Priscila Freitas Lemos, Vanessa Campos Andrade de Melo, Anamaria Mello Miranda Paniago, Igor Thiago Queiroz, Hiro Goto,
Background The development of rK39-based immunochromatographic rapid diagnostic tests represents an important advance for serodiagnosis of visceral leishmaniasis, being cheap and easy to use at the point of care (POC). Although the use of rK39 have considerably improved the sensitivity and specificity of serological tests compared with total antigens, great variability in sensitivity and specificity was reported. This study aimed at the evaluation of "Kalazar Detect™ Rapid Test, Whole Blood" (Kalazar ...
Tópico(s): Trypanosoma species research and implications
2020 - Public Library of Science | PLoS ONE
Produção Nacional
Igor Thiago Marques Mendonça, Crislaine Gruber,
Os momentos de interação síncrona entre professores e estudantes oportunizam discussões, troca de experiências e colaboração na educação a distância. Considerando a importância desses momentos e a multiplicidade de fatores que os influenciam, este trabalho avalia a percepção dos estudantes da EAD em relação às interações síncronas realizadas com auxílio de teleconferências. A partir de questionário, foram coletadas opiniões de 163 estudantes, 100 que utilizam Webconferência e 63 que utilizam Videoconferência. ...
Tópico(s): Education Pedagogy and Practices
2019 - | Informática na educação teoria & prática
Produção Nacional
Revisado por pares
José Ângelo Lauletta Lindoso, Carlos Henrique Valente Moreira, Mirella Alves Cunha, Igor Thiago Queiroz,
Visceral leishmaniasis (VL) is caused by Leishmania donovani and Leishmania infantum. The burden of VL is concentrated in tropical and subtropical areas; however, HIV infection has spread VL over a hyperendemic area. Several outcomes are observed as a result of VL-HIV coinfection. Impacts are observed in immunopathogenesis, clinical manifestation, diagnosis, and therapeutic response. Concerning clinical manifestation, typical and unusual manifestation has been observed during active VL in HIV-infected ...
Tópico(s): Trypanosoma species research and implications
2018 - Dove Medical Press | HIV/AIDS - Research and Palliative Care
Hécio Henrique Araújo de Moraes, Thiago de Santana Santos, Igor Batista Camargo, Ricardo José de Holanda Vasconcellos,
... Hécio Henrique Araújo DDS, Msc; de Santana Santos, Thiago DDS, Msc; Camargo, Igor Batista DDS, Msc; de Holanda Vasconcellos, Ricardo José ...
Tópico(s): Streptococcal Infections and Treatments
2013 - Lippincott Williams & Wilkins | Journal of Craniofacial Surgery
Produção Nacional
Revisado por pares
Hermes Ribeiro Luz, Francisco B. Costa, Hector Ribeiro Benatti, Vanessa do Nascimento Ramos, Maria Carolina de Azevedo Serpa, Thiago Fernandes Martins, Igor da Cunha Lima Acosta, Diego Garcia Ramirez, Sebastián Muñoz‐Leal, Alejandro Ramírez‐Hernández, Lina C. Binder, Márcio Port Carvalho, Vlamir José Rocha, Thiago C. Dias, Camila L. Simeoni, José Brites‐Neto, Jardel Brasil, Ana Maria Nievas, Patrícia Ferreira Monticelli, Maria Estela Gaglianone Moro, Beatriz Lopes, Daniel Moura de Aguiar, Richard de Campos Pacheco, Celso Eduardo de Souza, Ubiratan Piovezan, Raquel Soares Juliano, Kátia Maria Paschoaletto Micchi de Barros Ferraz, Matias Pablo Juán Szabó, Marcelo B. Labruna,
Background Brazilian spotted fever (BSF), caused by the bacterium Rickettsia rickettsii, has been associated with the transmission by the tick Amblyomma sculptum, and one of its main hosts, the capybara (Hydrochoerus hydrochaeris). Methods During 2015–2019, we captured capybaras and ticks in seven highly anthropic areas of São Paulo state (three endemic and four nonendemic for BSF) and in two natural areas of the Pantanal biome, all with established populations of capybaras. Results The BSF-endemic ...
Tópico(s): Mosquito-borne diseases and control
2019 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Marcelo B. Labruna, Thiago Fernandes Martins, Igor da Cunha Lima Acosta, María Carolina A. Serpa, Herbert Sousa Soares, Rodrigo Hidalgo Friciello Teixeira, Renata Carolina Fernandes‐Santos, Emília Patrícia Medici,
This study evaluated ticks and rickettsial exposure in 220 free-ranging lowland tapirs, Tapirus terrestris, from 2006 to 2018 in selected areas of three major biomes of Brazil – Atlantic Forest, Pantanal, and Cerrado. Overall, a total of 5970 tick specimens representing the following nine species were collected from tapirs: Amblyomma brasiliense, Amblyomma coelebs, Amblyomma dubitatum, Amblyomma ovale, Amblyomma parvum, Amblyomma sculptum, Amblyomma triste, Haemaphysalis juxtakochi, and Rhipicephalus ...
Tópico(s): Dermatological diseases and infestations
2021 - Elsevier BV | Ticks and Tick-borne Diseases
Produção Nacional
Revisado por pares
José Alexandre Felizola Diniz‐Filho, Kelly da Silva e Souza, Luis Maurício Bini, Rafael Loyola, Ricardo Dobrovolski, João Fabrício Mota Rodrigues, S. Lima‐Ribeiro, Levi Carina Terribile, Thiago F. Rangel, Igor Lucien Bione Dardenne Barbosa, Roniel Freitas, Iberê Farina Machado, Tainá Rocha, Maria Lúcia Lorini, Mariana M. Vale, Carlos A. Navas, Natan Medeiros Maciel, Fabricio Villalobos, Miguel Á. Olalla‐Tárraga, Sidney F. Gouveia,
Despite the widespread use of ecological niche models (ENMs) for predicting the responses of species to climate change, these models do not explicitly incorporate any population‐level mechanism. On the other hand, mechanistic models adding population processes (e.g. biotic interactions, dispersal and adaptive potential to abiotic conditions) are much more complex and difficult to parameterize, especially if the goal is to predict range shifts for many species simultaneously. In particular, the adaptive ...
Tópico(s): Animal Behavior and Reproduction
2019 - Wiley | Ecography
Produção Nacional
Revisado por pares
Lívia Beatriz Brenelli, Gabriela Félix Persinoti, João Paulo L. Franco Cairo, M.V. Liberato, Thiago Augusto Gonçalves, Igor Vinicius Ramos Otero, Pedro Henrique Mainardi, Claus Felby, Lara Durães Sette, Fábio M. Squina,
Abstract The repertoire of redox-active enzymes produced by the marine fungus Peniophora sp. CBMAI 1063, a laccase hyper-producer strain, was characterized by omics analyses. The genome revealed 309 Carbohydrate-Active Enzymes (CAZymes) genes, including 48 predicted genes related to the modification and degradation of lignin, whith 303 being transcribed under cultivation in optimized saline conditions for laccase production. The secretome confirmed that the fungus can produce a versatile ligninolytic ...
Tópico(s): Fungal Biology and Applications
2019 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Philipe B. de Oliveira, Tatiani Vitor Harvey, Hllytchaikra Ferraz Fehlberg, Josiane Moreira Rocha, Thiago Fernandes Martins, Igor da Cunha Lima Acosta, Marcelo B. Labruna, João Luiz Horácio Faccini, George Rêgo Albuquerque,
Tick-borne spotted fever in Brazil is known to be caused by two agents, Rickettsia rickettsii and Rickettsia parkeri. Nothing was known about these agents in one area of the Atlantic rainforest biome of Bahia state, where during March to June 2016, 356 rural dogs and 69 horses were sampled and their sera were processed through indirect immunofluorescence assay against antigens of R. rickettsii, R. parkeri, Rickettsia amblyommatis and Rickettsia bellii. Ticks collected from these dogs and horses ...
Tópico(s): Vector-Borne Animal Diseases
2019 - Springer Science+Business Media | Experimental and Applied Acarology
Produção Nacional
Revisado por pares
Thiago Lima Barretto, Igor D. Bandeira, João Gabriel Jagersbacher, Bianca Lima Barretto, Ângelo Frederico Souza de Oliveira e Torres, Norberto Peña, José García Vivas Miranda, Rita Lucena,
To assess the impact of tDCS on posture, gait and coordination of movements in subjects with cerebellar ataxia. This is a two-phase, double blind, auto matched, pilot study. Seven people were selected to participate in the study aged from 14 to 57. tDCS and sham-tDCS were applied at different times to all participants for 40 min over five consecutive days so that they were blind to which of the two techniques was applied at any one time. The area stimulated was the bilateral motor cortex. Subjects ...
Tópico(s): Neurological disorders and treatments
2019 - Elsevier BV | Clinical Neurology and Neurosurgery
Produção Nacional
Revisado por pares
Sebastián Muñoz-Léal, Luı́s Felipe Toledo, José M. Venzal, Arlei Marcili, Thiago Fernandes Martins, Igor da Cunha Lima Acosta, Adriano Pintér, Marcelo B. Labruna,
In this study, we present a morphological description of immature and adult specimens of Ornithodoros saraivai n. sp., a tick associated with the frog Cycloramphus boraceiensis (Cycloramphidae) at São Sebastião island, located in the São Paulo state seaboard, Brazil. While larvae of O. saraivai are ecologically related to Ornithodoros faccinii, another soft tick associated with cycloramphids, the combination of 7 sternal pairs, 16 dorsal pairs, a pyriform dorsal plate and a partially toothed hypostome ...
Tópico(s): Parasite Biology and Host Interactions
2017 - Elsevier BV | Ticks and Tick-borne Diseases
Produção Nacional
Revisado por pares
Thiago Pires Brito, Igor Moreira Hazboun, Fernando Laffitte Fernandes, Lucas Ricci Bento, Carlos Eduardo Monteiro Zappelini, Carlos Takahiro Chone, Agrício Nubiato Crespo,
Although the incidence of Deep Cervical Abscess (DCA) has decreased mainly for the availability of antibiotics, this infection still occurs with considerable frequency and can be associated with high morbidity and mortality.
Tópico(s): Infectious Diseases and Tuberculosis
2016 - Elsevier BV | Brazilian Journal of Otorhinolaryngology
Produção Nacional
Revisado por pares
G. Delfino, Sabrina Messa Peviani, João Luíz Quagliotti Durigan, Thiago Luiz Russo, Igor L. Baptista, Mário Ferretti, Anselmo Sigari Moriscot, Tânia F. Salvini,
Objective The aim of this study was to assess the mRNA levels of atrogin-1, muscle ring finger 1, and myostatin in rat quadriceps after anterior cruciate ligament (ACL) transection. Design Wistar rats were randomized into three different groups: ACL (surgery and ACL transection), sham (surgery without ACL transection), and control. Vastus medialis, rectus femoris, and vastus lateralis muscles were harvested at 1, 2, 3, 7, and 15 days after ACL transection. The mRNA levels of atrogin-1, muscle ring ...
Tópico(s): Muscle Physiology and Disorders
2012 - Lippincott Williams & Wilkins | American Journal of Physical Medicine & Rehabilitation
Produção Nacional
Revisado por pares
Thiago G. Silva, Igor M. R. Moura, Paulo E. Cabral Filho, Maria I.A. Pereira, Clayton A. Azevedo Filho, Goreti Pereira, Giovannia A. L. Pereira, Adriana Fontes, Beate S. Santos,
Abstract In this study, we present the optimization of the optical properties of Mn 2+ doped ZnSe QDs (also referred to as d‐dots) coated with thioglycolic acid in aqueous medium. The nanoparticles were characterized by ionic coupled plasma, electron paramagnetic resonance, transmission electron microscopy and X‐ray diffractometry. By applying a controlled dose of UV irradiation, we obtained efficient orange emitting d‐dots ( 4 T 1 → 6 A 1 transition centered at 580 nm). The results point out to a doping ...
Tópico(s): Quantum Dots Synthesis And Properties
2016 - Wiley | Physica status solidi. C, Conferences and critical reviews/Physica status solidi. C, Current topics in solid state physics
Produção Nacional
Revisado por pares
Saulo Gil, Wilson Jacob Filho, Samuel Katsuyuki Shinjo, Eduardo Ferriolli, Alexandre Leopold Busse, Thiago Junqueira Avelino‐Silva, Igor Longobardi, Gersiel Nascimento de Oliveira Júnior, Paul Swinton, Bruno Gualano, Hamilton Roschel,
Abstract Background Strength and muscle mass are predictors of relevant clinical outcomes in critically ill patients, but in hospitalized patients with COVID‐19, it remains to be determined. In this prospective observational study, we investigated whether muscle strength or muscle mass are predictive of hospital length of stay (LOS) in patients with moderate to severe COVID‐19 patients. Methods We evaluated prospectively 196 patients at hospital admission for muscle mass and strength. Ten patients ...
Tópico(s): COVID-19 Clinical Research Studies
2021 - Springer Science+Business Media | Journal of Cachexia Sarcopenia and Muscle
Produção Nacional
Revisado por pares
Douglas V.O. Lessa, Thiago Pereira dos Santos, Igor M. Venâncio, Ana Cláudia Aoki Santarosa, Edmundo C. dos Santos, Felipe Antonio de Lima Toledo, Karen Badaraco Costa, Ana Luíza Spadano Albuquerque,
Expansions of coastal upwelling spots along the Brazilian coast were previously reported for Marine Isotope Stage (MIS) 5, but open questions remain regarding the climatic mechanisms and the periodicity of such changes. Based on two marine sediment cores, we provide evidence for multiple intensifications of the upwelling regime off the Southeast Brazilian margin (SBM) during several interglacials and highlight the major role of eccentricity as the responsible forcing. In addition, we show a two-step ...
Tópico(s): Geological formations and processes
2019 - Elsevier BV | Global and Planetary Change
Produção Nacional
Revisado por pares
Daniela da Fonseca Pacheco, Thiago Roberto Lima Romero, Igor Dimitri Gama Duarte,
The participation of endocannabinoids in central and peripheral antinociception induced by several compounds has been shown by our group. In this study, we investigated the effect of endocannabinoids on the central antinociception induced by ketamine. The nociceptive threshold for thermal stimulation was measured using the tail-flick test in Swiss mice. The drugs were administered intracerebroventricularly. Probabilities less than 5% (p < 0.05) were considered to be statistically significant (Two-way ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
2019 - Elsevier BV | Neuroscience Letters
Produção Nacional
Revisado por pares
Douglas V.O. Lessa, Thiago Pereira dos Santos, Igor M. Venâncio, Ana Luíza Spadano Albuquerque,
Paleoceanographic reconstructions in upwelling regions can provide relevant information about changes in primary productivity, ocean–atmosphere interactions and the carbon budget. Here, we assessed new data on planktonic foraminifera from a sediment core located near to coastal upwelling zones along the Brazilian coast. Our new data was combined with previous records to reveal the state of upwelling systems along the western South Atlantic margin throughout the last two deglacial and interglacial ...
Tópico(s): Marine Biology and Ecology Research
2017 - Elsevier BV | Global and Planetary Change
Produção Nacional
Revisado por pares
Lívia Caroline Resende Silva, Marina Gomes Miranda e Castor, Larissa Caldeira Navarro, Thiago Roberto Lima Romero, Igor Dimitri Gama Duarte,
NSAIDs represent some of the most widely prescribed drugs for relief of short-term fever, pain and inflammation. The participation of the opioid system in the peripheral is poorly understood. The aim of this study was evaluate the role of opioid system in the peripheral antinociception by diclofenac and dipyrone. To test this hypothesis, opioid receptor antagonists were evaluated using the rat paw pressure test, in which pain sensitivity is increased by intraplantar injection of prostaglandin E2 ( ...
Tópico(s): Anesthesia and Pain Management
2016 - Elsevier BV | Neuroscience Letters
Produção Nacional
Revisado por pares
André Vajgel, Thiago de Santana Santos, Igor Batista Camargo, David Moraes de Oliveira, José Rodrigues Laureano Filho, Ricardo José de Holanda Vasconcellos, Sergio Monteiro Lima, Valfrido Antonio Pereira‐Filho, Andreas Mueller, P. Juergens,
This multicentre study aimed to investigate long-term radiographic and functional results following the treatment of condylar fractures using an angulated screwdriver system and open rigid internal fixation with an intraoral surgical approach. Twenty-nine patients with a total of 32 condylar fractures were evaluated. The patients were investigated prospectively based on the following variables: age, sex, aetiology, side, location and classification of the fracture, degree of displacement, associated ...
Tópico(s): Dental Radiography and Imaging
2014 - Elsevier BV | Journal of Cranio-Maxillofacial Surgery
Produção Nacional
Revisado por pares
Ana F. Almeida‐Santos, Pedro H. Gobira, D Souza, Renata Cristina Mendes Ferreira, Thiago Roberto Lima Romero, Igor Dimitri Gama Duarte, Daniele C. Aguiar, Fabrício A. Moreira,
Aripiprazole is an antipsychotic that acts as a partial agonist at dopamine D2 receptors, with a favorable pharmacological profile. Due to its unique mechanism of action, this compound has potential application as a substitutive therapy for drug addiction. Considering that distinct neural systems subserve the addictive and analgesic actions of opioids, we tested the hypothesis that aripiprazole selectively inhibit the abuse-related, but not the antinociceptive, effects of morphine. The drugs were ...
Tópico(s): Neuroscience and Neuropharmacology Research
2014 - Elsevier BV | European Journal of Pharmacology
Produção Nacional
Revisado por pares
Daniela da Fonseca Pacheco, Thiago Roberto Lima Romero, Igor Dimitri Gama Duarte,
It is generally believed that NMDA receptor antagonism accounts for most of the anesthetic and analgesic effects of ketamine, however, it interacts at multiple sites in the central nervous system, including NMDA and non-NMDA glutamate receptors, nicotinic and muscarinic cholinergic receptors, and adrenergic and opioid receptors. Interestingly, it was shown that at supraspinal sites, ketamine interacts with the μ-opioid system and causes supraspinal antinociception. In this study, we investigated ...
Tópico(s): Neuroscience and Neuropharmacology Research
2014 - Elsevier BV | Brain Research
Produção Nacional
Revisado por pares
Thiago Roberto Lima Romero, Igor DG Duarte,
To investigate the contribution of K(+) channels on peripheral antinociception induced by ketamine.Prospective experimental study.110 male Wistar rats weighing 160-200 g.The paw pressure required to elicit limb flexion was designated as the nociceptive threshold. Hyperalgesia was induced by intraplantar injection of prostaglandin E2 . All drugs were administered locally into the right hind paw of rats. Ketamine was administered into the right hind paw 2 hours and 55 minutes after local injection of ...
Tópico(s): Neuroscience and Neuropharmacology Research
2013 - Elsevier BV | Veterinary Anaesthesia and Analgesia
Produção Nacional
Revisado por pares
Thiago Roberto Lima Romero, Igor Dimitri Gama Duarte,
Although the antinociceptive effects of N-palmitoyl-ethanolamine (PEA) were first characterized nearly 50 years ago, the identity of the mechanism that mediates these actions has not been elucidated. The present study investigated the contribution of K+ channels on peripheral antinociception induced by the CB2 agonist PEA. Nociceptive thresholds to mechanical paw stimulation of Wistar rats treated with intraplantar prostaglandin E2 to induce hyperalgesia were measured, and other agents were also ...
Tópico(s): Neuroscience and Neuropharmacology Research
2012 - Elsevier BV | Journal of Pharmacological Sciences
Produção Nacional
Revisado por pares
Thiago Roberto Lima Romero, Igor Dimitri Gama Duarte,
The l-arginine/nitric oxide/cyclic GMP pathway has been proposed as the mechanism of action for peripheral antinociception concerning several groups of drugs, including opioids and nonsteroidal analgesics. The aim of the present study was to investigate the involvement of the l-arginine/NO/cGMP pathway on antinociception induced by xylazine, an α2-adrenoceptor agonist extensively used in veterinary medicine and animal experimentation. The rat paw pressure test was used by inducing hyperalgesia via ...
Tópico(s): Neuropeptides and Animal Physiology
2009 - Elsevier BV | European Journal of Pharmacology