James J. Liu, Paddy A. Phillips, Louise M. Burrell, Brian Buxton, Colin I. Johnston,
... AVP (SAVP) and d(CH 2 ) 5 D‐Ileu 2 11eu 4 AVP (Ileu 2 Ileu 4 AVP), respectively. 3. The V 1 antagonist ... antagonists OPC‐31260 (3X10 − ‐ 6 mol/L) and Ileu 2 Ileu 4 AVP significantly antagonized the AVP‐induced contraction ( ... V1 receptor antagonist. The results also indicate that Ileu 2 Ileu 4 AVP may be a V l receptor ...
Tópico(s): Electrolyte and hormonal disorders
1994 - Wiley | Clinical and Experimental Pharmacology and Physiology
... rat proximal nephron function. The effect of infusing Ileu 5 -angiotensin II into the peritubular capillaries on ... different tubules associated with peritubular infusion of either Ileu 5 -angiotensin II or isotonic saline solution. Infusion ... infusion. The results indicate that the presence of Ileu 5 -angiotensin II on the capillary side of ... le rat. L'effet de l'infusion de Ileu 5 -angiotensine II dans les capillaires peritubulaires sur ... dont les capillaires ont ete infuses soit avec Ileu 5 -angiotensine II soit avec du solute sale ...
Tópico(s): Electrolyte and hormonal disorders
1974 - Elsevier BV | Kidney International
... of a synthetic analogue of atrial natriuretic peptide (Ileu-ANP) on haemodynamic, hormonal, and electrolyte excretion indices ... failure. Patients received in random order placebo or Ileu-ANP infusions (5 μg/min) for 4 h ... at least 1 week apart. Compared with placebo, Ileu-ANP caused significant reductions in mean systemic arterial ... increase in heart rate or plasma noradrenaline. With Ileu-ANP infusion, plasma renin activity, angiotensin, arginine vasopressin, ... values. Plasma cortisol and aldosterone increased after stopping Ileu-ANP. Neither urine volume nor sodium excretion rate ...
Tópico(s): Cardiovascular Function and Risk Factors
1986 - Elsevier BV | The Lancet
... 1 2 Cys 5 Val 14 Met 12 Ileu 5 Leu 36 Tyr 3 Phe 20 Trp ... 1 2 Cys 7 Val 15 Met 10 Ileu 4 Leu 35 Tyr 2 Phe 19 Trp ... 1 2 Cys 7 Val 15 Met 10 Ileu 5 Leu 34 Tyr 2 Phe 18 Trp ... 1 2 Cys 1 Val 9 Met 9 Ileu 2 Leu 10 Tyr 2 Phe 10 Trp ... 1 2 Cys 1 Val 9 Met 10 Ileu 2 Leu 10 Tyr 2 Phe 10 Trp ...
Tópico(s): Protist diversity and phylogeny
1968 - Pergamon Press | Comparative Biochemistry and Physiology
Edwin B. Kalan, M.P. Thompson, Rae Greenberg, L. Pepper,
... followed by isoleucine.The data indicate either an ileu-ileu-val or an ileu-val-ileu C-terminal sequence in each variant.Molecular weights ...
Tópico(s): Animal Genetics and Reproduction
1965 - Elsevier BV | Journal of Dairy Science
... 8 amino acid residue of [1-asp,5-ileu]-angiotensin II for adrenal medullary stimulation. Isolated cat ... tyr]-angiotensin II; [8-ala]-angiotensin II; [5-ileu,8-(3-amino-4-phenylbutyric acid)]-angiotensin II (referred to as [8-APB]-angiotensin II); [5-ileu,8-(DL-3-amino-3'-phenylisobutyric acid)]-angiotensin ... 2 ),5-val]-angiotensin II; [1-asp,5-ileu]-angiotensin I; tetradecapeptide. Three peptides (angiotensin II, [8- ...
Tópico(s): Pharmacogenetics and Drug Metabolism
1971 - Lippincott Williams & Wilkins | Circulation Research
... 8 amino acid residue of [1-asp,5-ileu]-angiotensin II for adrenal medullary stimulation. Isolated cat ... tyr]-angiotensin II; [8-ala]-angiotensin II; [5-ileu,8-(3-amino-4-phenylbutyric acid)]-angiotensin II (referred to as [8-APB]-angiotensin II); [5-ileu,8-(DL-3-amino-3'-phenylisobutyric acid)]-angiotensin ... NH2),5-val]-angiotensin II; [1-asp,5-ileu]-angiotensin I; tetradecapeptide. Three peptides (angiotensin II, [8- ...
Tópico(s): Pharmacogenetics and Drug Metabolism
1971 - Lippincott Williams & Wilkins | Circulation Research
Kenneth Steven, Darrell H. Thorpe,
... tubule. Infusion, at 20 n1 min ‐1 , of Ileu 5 ‐angiotensin II [(Ileu 5 )‐A II] (20 ng m1 ‐1 ) into ... change resulted from infusion with a mixture of (Ileu 5 )‐A II and (Sar 1 , Ala 8 )‐ ... in this mixture blocked the inhibitory effect of (Ileu 5 )‐A II on RPFR, but infusion of ...
Tópico(s): Hormonal Regulation and Hypertension
1977 - Wiley | Acta Physiologica Scandinavica
Jean Daniel Sraer, Josée Sraer, Raymond Ardaillou, Odile Mimoune,
... bind to fresh membranes. Angiotensin II, angiotensin I, ileu 8 -angiotensin II and sarc 1 -ileu 8 -angiotensin II were all equally effective as ... fraiches. L'angiotensine II, l'angiotensine I, la ileu 8 -angiotensine II et la sarc 1 -ileu 8 -angiotensine II sont des inhibiteurs competitifs de ...
Tópico(s): Receptor Mechanisms and Signaling
1974 - Elsevier BV | Kidney International
Tadakazu Tokumura, Yuki Tsushima, Kimio Tatsuishi, Masanori Kayano, Yoshiharu Machida, Tsuneji Nagai,
... L-leucine (L-Leu) and L-isoleucine (L-Ileu) to act as competing agents was evaluated by ... of CN, employing a Sartorius absorption simulator. L-Ileu showed a stronger competing action than L-Leu. ... was enhanced by the simultaneous administration of L-Ileu as a competing agent; Cmax was 1.9 ... vivo competing effects of L-Leu and L-Ileu appeared to be in agreement with the in ...
Tópico(s): Cancer Treatment and Pharmacology
1986 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin
Roger Acher, Ulla-Riitta Laurila, Claude Fromageot,
... enchaînements Asp·Tyr·Arg·Gly, Arg·Gly·Tyr·Ileu·Leu et Asp(NH2)·Ala·Tyr·Gly·Sér· ... linkages Asp·Tyr·Arg·Gly, Arg·Gly·Tyr·Ileu·Leu and Asp(NH2)·Ala·Tyr·Gly·Ser· ... entsprechen: Asp·Tyr·Arg·Gly, Arg·Gly·Tyr·Ileu·Leu und Asp(NH2)·Ala·Tyr·Gly·Ser· ...
Tópico(s): Insect Utilization and Effects
1956 - Elsevier BV | Biochimica et Biophysica Acta
... peptides, Ala[Tyr,AspNH2], [Ala,Tyr,Asp,Pro]Ileu.Thr and [Ala,Tyr,Asp]Pro. Ileu.Thr.Ser, were isolated by the aid of ... longest, a heptapeptide: Acetyl.Ala.Tyr.AspNH2.Pro.Ileu.Thr.Ser. The acetylpeptides are probably derived from ...
Tópico(s): Biochemical and Structural Characterization
1959 - Elsevier BV | Biochimica et Biophysica Acta
... positions 26 and 29 is Cys-Leu-Thr-Ileu in hFSH-P, hTSH-& and bTSH-P, whereas oLH-fi contains the sequence Cys-Ileu-Thr-Phe, and hCG-@ and hLH-P contain the sequence Cys-Ileu-Thr-Val.
Tópico(s): Reproductive Biology and Fertility
1976 - Elsevier BV | Journal of Biological Chemistry
Philippe Meyer, A. Papadimitriou, Manuel Worcel,
... of the two competitive antagonists (1-Asn, 5-Ileu, 8-Ala)-angiotensin II and (1-Asn, 5-Ileu, 8-Ileu)-angiotensin II with angiotensin II receptors was tested ...
Tópico(s): Hormonal Regulation and Hypertension
1974 - Wiley | British Journal of Pharmacology
J. P. Bussien, Jérôme Biollaz, Bernard Waeber, J. Nussberger, G. A. Turini, Hans R. Brunner, Françoise Brunner‐Ferber, Héctor W. Gómez, E S Otterbein,
... acids in the rat sequence, L-364, 343 (Ileu-ANP), was infused intravenously at increasing rates (1- ... already with a cumulative dose of 55 micrograms Ileu-ANP and further rises were directly related to ... higher doses. These findings provide strong evidence that Ileu-ANP acts as a vasodilator in normal volunteers.
Tópico(s): Cardiovascular and exercise physiology
1986 - Lippincott Williams & Wilkins | Journal of Cardiovascular Pharmacology
Guillermo N. Moroni, Patricia Bogdanov, Margarita C. Briñón,
... the corresponding AZT analogs, namely AZT-Leu, AZT-iLeu and AZT-Val. A carboxyl acid derivative (AZT- ... K. pneumoniae ATCC 10031) was AZT-Leu > AZT-iLeu > AZT-Val > AZT-Ac > AZT. On the other ... was AZT-Leu > AZT-Val=AZT-Ac > AZT-iLeu > AZT. The most effective antibacterial drug AZT-Leu, ...
Tópico(s): Biochemical and Molecular Research
2002 - Taylor & Francis | Nucleosides Nucleotides & Nucleic Acids
Daniela Perani, Fabio Grassi, Sandro Sorbi, Benedetta Nacmias, Silvia Piacentini, P. Piersanti, Leandro Provinciali, L. Amaducci, Ferruccio Fazio,
... Alzheimer's disease (FAD) and APP717 Val to Ileu mutation. The aim of the study was to ... present in FAD patients with APP717 Val to Ileu mutation. Cerebral hypometabolism may occur in pre‐symptomatic ...
Tópico(s): Mitochondrial Function and Pathology
1997 - Wiley | European Journal of Neurology
Jian-Jun Zhao, Wei-Chun Yang, Xiaoqing Wang, Tianzhu Jin,
Two lanthanide complexes, Ln2(Ileu)4(ClO4)6 · 8H2O, were synthesized in aqueous solution (where Ln Nd or Er, Ileu = l-isoleucine). The crystal structure of the neodymium ...
Tópico(s): Magnetism in coordination complexes
1995 - Elsevier BV | Polyhedron
M. Charles, M. Rovery, A. Guidoni, P. Desnuelle,
... process involves the specific splitting of a Lys-Ileu bond belonging to the N-terminal sequence of ... trypsin have the same C-terminal sequence: Thr-(Ileu,Glu(NH2))-Ala-Asp(NH2). This identity is ...
Tópico(s): Diet, Metabolism, and Disease
1963 - Elsevier BV | Biochimica et Biophysica Acta
P Jaquenoud, R. A. Boissonnas,
... current distribution, affords the desired cyclic nonapeptide amides : Ileu 8 ‐oxytocin and Val 8 ‐oxytocin. When tested ...
Tópico(s): Molecular Spectroscopy and Structure
1961 - Wiley | Helvetica Chimica Acta
The pressor activity of pure natural asp 1 ileu 5 -angiotensin II, and synthetic asparginyl 1 -val 5 , asp 1 -val 5 , asp 1 -ileu 5 , and ß-asp 1 -val 5 -angiotensin ...
Tópico(s): ATP Synthase and ATPases Research
1964 - American Physiological Society | American Journal of Physiology-Legacy Content
... by temperature. It was found that Hypertensin and ileu 5 angiotensin II exhibited equal immunological activities, whereas ileu 5 angiotensin I displayed less than 1% of ...
Tópico(s): Pharmacological Effects and Assays
1970 - Oxford University Press | European Journal of Endocrinology
Lynn E. S̄pitler, E. Benjamini, Janis Dillaha Young, Harvey Kaplan, H. Hugh Fudenberg,
... 93-112 of TMVP and having the sequence Ileu-Ileu-Glu-Val-Glu-AspNH(2)-GluNH(2)-Ala- ...
Tópico(s): Immunotherapy and Immune Responses
1970 - Rockefeller University Press | The Journal of Experimental Medicine
... NH 2 ), Ala(NH 2 ), Val(NH 2 ), Ileu(NH 2 ), nor Gly‐Leu, Gly‐Phe, Gly‐ ... of hydrophobic amino acids (Phe, Leu, Ala, Val, Ileu but not Trp) or of tyrosine. The highest ...
Tópico(s): Protein Hydrolysis and Bioactive Peptides
1971 - Wiley | European Journal of Biochemistry
Noshi Minamiura, Yoshikazu Matsumura, Juichiro FUKUMOTO, Takehiko Yamamoto,
... determined as follows: Arg•Gly•Pro•Pro•Phe•Ileu•Val. Liberation of N-terminal Arg with trypsin ... Also, splitting off of Val and Den or Ileu•Val at the C-terminus by carboxypeptidase, or ...
Tópico(s): Animal Genetics and Reproduction
1972 - Oxford University Press | Agricultural and Biological Chemistry
Tsuyoshi Kono, Fumimaro Oseko, Fumitake Ikeda, Masataka Nanno, Jiro Endo,
Biological activity of ileu8-angiotensin III (AIIIA) was studied in man. In 5 normal men intravenous infusion of 200 ng/kg/min of AIIIA for 30 minutes from 0900 h had no effect on blood pressure (BP) but caused a decrease in plasma renin activity (PRA) and an increase in plasma aldosterone (PA). This dose did not inhibit pressor and steroidogenic actions of angiotensin II (AII) infused into the normal men at a rate of 20 ng/kg/min for 30 minutes. In 3 patients with Bartter's syndrome 260-1,200 ng/kg/ ...
Tópico(s): Hormonal Regulation and Hypertension
1976 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
Kazuhiko Iwatsuki, Shigetoshi Chiba,
... responses and relative potency (dopamine =1) was: N-Ileu-dopamine (0.4)>N-Ala-Glu-dopamine (0. ... longer than that of dopamine. Dopamine and N-Ileu-dopamine which has the most potent secretagogue property ...
Tópico(s): Diabetes Treatment and Management
1980 - Japanese Pharmacological Society | The Japanese Journal of Pharmacology
M. T. A. Evans, Michael C. Phillips, M.N. Jones,
... decreased by removing the three C‐terminal residues (Ileu Ileu Val) with carboxypeptidase‐A. This modification drastically reduces ...
Tópico(s): Muscle metabolism and nutrition
1979 - Wiley | Biopolymers
Jennifer E. Shook, Wieslaw M. Kazmierski, William S. Wire, P K Lemcke, Victor J. Hruby, Thomas F. Burks,
... Leu-Val-Thr-Leu-Phe- Lys-Asn - Ala-Ileu-Ileu-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu ( ...
Tópico(s): Pharmacological Receptor Mechanisms and Effects
1988 - American Society for Pharmacology and Experimental Therapeutics | Journal of Pharmacology and Experimental Therapeutics
Rashmi Gopal-Srivastava, P B Hylemon,
... Ser/C ys)-Arg-Thr-Lys-Leu-Val-Ileu-Thr-Ileu-Gly-Ala-Ser.The purified enzyme was active ...
Tópico(s): Biochemical effects in animals
1988 - Elsevier BV | Journal of Lipid Research