Jonathan Northcroft, Waldemar Januszczak, John Dugdale, Nicholas Pyke, Matthew Wall, Barbara Hall, Nigel Botherway, Tracey Cox, Hugh Wilson, Harry Cragoe, James McDermott, Jim Munro, Peter Hayes, Helen Davies, Sally Brock, John Peter, V S, Donald Regan, Mark Hodgkinson, Amanda Ursell, Jonathan Miller, Robert Chalmers, Andrew Longmore, J D, P Hutcherson, Tim Nagle, Lucy Adams, A M, Frank Whitford, Dom Pleasance, Ivo Tennant, R Kent, Ferdinand Mount, David Gower, Kathryn Cooper, William Lewis, P D, David Smith, Humphrey Carpenter, Tim Richards, Peter Sharkey, John Goetz, Paul Broks, Nick Pitt, Neil Wormald, Mike Roberts, E P, Clive Davis, Tim Pigott-Smith, Stephen Grey, K R, Margret Geraghty, David O'Regan, Peter Foster, Andrew Porter, Larry Lindsey, C D, Joseph Dunn, Louise Corsin, Tony Allen-Mills, Simon Wilde, D C, Martin James, Robert Winnett, T E, Irwin Stelzer, Robert Hewison, Peter Wilson, Rosie Millard, Lawrence Dallaglio, Anita Burgh, David Dougill, C S, Homer Simpson, M Tait, Frank Graham, Anna Bruning, Thrasy Petropoulos, H C, David Hewson, Alison Jay, Jeff Simpson, Jonathon Carr-Brown, Alasdair Reid, Margarette Driscoll, Geraldine Hackett Education Correspondent, Hugh Canning, Jeremy Clarkson, Janet Anderson, Edward Porter, Peter Conradi, Stewart Lee, Mike Pattenden, S L, Victoria Segal, Patricia Nicol, Anthony Peregrine, Dermot Finnigan, Lucy Morgan Edwards, John Gallagher, Greg Critser, Eben Black, Dave Pollard, John O'Donnell, Kevin Jackson, Sarah Dempster, Travis Elborough, Graham Clutton, Greg Struthers, Lydia Slater, Christopher de Hauteville Bell, Shelley von Strunckel, Paul Donovam, Ruth Mielcarek, Jeremy Guscott, Paula Robinson, Andrew Thomas, Joesph Stiglitz, Peter Parker, John Thompson, Stuart Wavell, Paul Donovan, Anne Irvine, Tom Conran, Pat Cash, Joanna Simmon, Sean McGrady, Vincent Crump, Michael Cole, Paul Kimmage, Chris Woodhead, Julian Rendell, Name withheld, Angela Brooks, Lucinda Kemeny, Monsieur Mangetout, Jasper Gerard, Derek Clements, Michael Woodhead, Paul Driver, M E I, Gyorgy Ligeti, Nicholas Hellen, Sally Jones, Kerry Shale, Mary Gold, Ian Hawkey, Caroline Scott, Christopher Morgan, David Leppard, Nitin Mehta, Paul Durman, Mark Ludlow, Lisa Grainger, Richard Girling, Mark Edwards, Susan Clark, Kira Cochrane, Danny O'Brien, Charles Kirwan-Taylor, Phil Baker, Nicola Shuman, Christina Lamb, Victoria O'Brien, Simon Veness, Miranda Eeles, C L, Raymond Keene, Gareth Huw Davies, Marion Welham, Paul Bew, David Cracknell, Stanley Stewart, Katrina Manson, Tim Kavanagh, Cosmo Landesman, Robbie Hudson, David Walton, Diana Wright, Liz Grant, Stephen Jones, Dominic O'Connell, Barry Flatman, Uzi Mahnaimi, Richard Evans, Louise Armitstead, Natalie Graham, Tim Moorey, M J, Caroline Donald, Kate Rew, S D, Mike Nicholls, Fiona Terry, Philip Welsby, David Walsh, Miranda Seymour, S P, Tony Stephens, John Elliott, Aleks Sierz, Stephen Armstrong, Elizabeth Jane Howard, Mark Anstead, Theo Fennell, Nick MacKinnon, Colin McDowell's, Clare Nolan, N R, M L, Alan Corner, Shane Watson, William Rees-Mogg, Wayne Shelford, Stephanie Calman, P N, Maurice Chittenden, Larry Khongwir, Jonathan Clayton, Keith Wilyman, T N, Richard Brooks Arts Editor, Zac Goldsmith, Richard Rae, Ray Hutton, Prof Gideon Garter, Jon Ungoed-Thomas, Tim Linacre, Lauren Quaintance, Robert Macfarlane, Jonathan Leake, P J L, M E, Michael Sheridan, David Vernon, Amanda Craig, Niall Ferguson, Clare Francis, John Harlow, Robert Winnett Consumer Affairs Correspondent, Brian Griffin, James Foxall, John Waples, E p, Jeremy Hart, A A Gill, Bernice Rubens, Matthew Campbell, Smith, Simon Long, Simon Jenkins, Stephen Pettitt, Lewis Stuart, Jonathan Carr-Brown, James Fenton, Claudia Croft, Maria McErlane, T L, Alan Coren, Imre Karacs, Sally Kinnes, Naomi Caine, Liam Clarke, David Wickers, Nigel Powell, Brian Doogan, Michael Clower, Minette Marrin, Mark Hodson, Graham Norwood, James Knight, James Woods, Lois Rogers Medical Editor, Joe Lovejoy, R Evans, Rupert Steiner, David Budworth, William Lewis Business editor, F Hale, Andrew Davidson, Paul Stephen Lubicz, O Robinson, Hugh Pearman, J H, Dan Cairns, Duncan Foster, David Smith Economics Editor, (Dr) Rosalind Miles, Grey Groover, Tom Deveson, Dave Callaghan, Matthew Atkinson, Isabel Unsworth, Sarah Baxter, Martin Booth, Bob Dwyer, Matthew Goodman, India Knight, P Blackwood, Simon Howard, Ed Hughes, Melanie Jennings, Jason Dawe, Dominic Rushe, Richard Lewis,
... Other Tales from the American Underground by Eric Schlosser Allen Lane £10.99 pp304 Yoga for People ...
2003 - Gale Group | Sunday Times HA GDA
Tı́mea Imre, Gitta Schlosser, Gabriella Pòcsfalvi, Rosa Anna Siciliano, Éva Molnár‐Szöllősi, T. Kremmer, Antonio Malorni, Károly Vékey,
Abstract A new anionic surfactant (RapiGest SF) was successfully used for site‐specific analysis of glycosylation in human alpha‐1‐acid glycoprotein (AGP). By means of this analytical approach combined with capillary HPLC‐mass spectrometry (and tandem mass spectrometry), the N‐linked glycosylation pattern of AGP was explored. On the basis of mass matching and MS/MS experiments ca 80 different AGP‐derived glycopeptides were identified. Glycosylation shows a markedly different pattern for the various ...
Tópico(s): Mass Spectrometry Techniques and Applications
2005 - Wiley | Journal of Mass Spectrometry
T. Kremmer, Eva Szöllösi, M. Boldizsár, B. Vincze, Krisztina Ludányi, Tı́mea Imre, Gitta Schlosser, Károly Vékey,
Human serum acid alpha-1-glycoprotein (AGP, orosomucoid) content of healthy individuals and cancer patients was measured, isolated and purified using a protocol of fast and biocompatible sample preparation, ion exchange and dye-ligand affinity chromatographic methods. In comparison to the healthy individuals significantly higher serum AGP levels were found in a wide spectrum of cancer patients, indicating its diagnostic value in the malignant disease. Oligosaccharide content of AGP samples was separated ...
Tópico(s): Advanced Proteomics Techniques and Applications
2004 - Wiley | Biomedical Chromatography
Imre Blank, Laurent B. Fay, Frederick J. Lakner, Manfred Schlosser,
The formation of 4-hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF) and 2(or 5)-ethyl-4-hydroxy-5(or 2)-methyl-3(2H)-furanone (EHMF) from pentose sugars was studied in Maillard model systems. The amounts generated at 90 °C for 1 h were determined by isotope dilution assay (IDA). The internal standards used for IDA, i.e., [13C2]HDMF and [2H3]EHMF, were prepared in good overall yields in three steps: addition of labeled acetaldehyde or propionaldehyde to tert-butyloxycarbonyl (Boc)-protected and lithiated 3-butyn- ...
Tópico(s): Advanced Glycation End Products research
1997 - American Chemical Society | Journal of Agricultural and Food Chemistry
Anna Kiss-Szemán, Luca Takács, Zoltán Orgován, Pál Stráner, Imre Jákli, Gitta Schlosser, Simonas Masiulis, Veronika Harmat, Dóra K. Menyhárd, András Perczel,
The structure of porcine AAP (pAAP) in a covalently bound complex with meropenem was determined by cryo-EM to 2.1 Å resolution, showing the mammalian serine-protease inhibited by a carbapenem antibiotic. AAP is a modulator of the ubiquitin-proteasome degradation system and the site of a drug-drug interaction between the widely used antipsychotic, valproate and carbapenems. The active form of pAAP - a toroidal tetramer - binds four meropenem molecules covalently linked to the catalytic Ser587 of the serine- ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2022 - Royal Society of Chemistry | Chemical Science
Péter Bárány, Rita Szabó, Imre Kovács, Tamás Czuczi, Csenge Lilla Szabó, Angéla Takács, Eszter Lajkó, Orsolya Láng, László Kőhidai, Gitta Schlosser, Szilvia Bősze, Gábor Mezó, Ferenc Hudecz, Antal Csámpai,
Inspired by the well-established clinical evidence about the interplay between apoptotic TRAIL (tumour necrosis factor-related apoptosis-inducing ligand) mechanism and reactive oxygen species (ROS)-mediated oxidative stress, a set of novel ONC201 hybrids containing the impiridone core and one or two differently positioned ferrocenylalkyl groups were synthesised in our present work. These two types of residues have been implicated in the aforementioned mechanisms associated with cytotoxic activity. ...
Tópico(s): Synthesis and Biological Evaluation
2018 - Multidisciplinary Digital Publishing Institute | Molecules
�. Sz�ll si, T. Kremmer, K. Lud�nyi, Tı́mea Imre, Gitta Schlosser, M. Boldizs�r, B. Vincze, K. V�key,
Tópico(s): Protein purification and stability
2004 - Springer Science+Business Media | Chromatographia
... in Fisheries and Aquatic Sciences 106, 65–85. Schlosser, I. J. (1987). The role of predation in ...
Tópico(s): Fish biology, ecology, and behavior
2002 - Wiley | Journal of Fish Biology
... 841–847. 4Vashishta R, Soler ZM, Nguyen SA, Schlosser RJ. A systematic review and meta-analysis of asthma outcomes following endoscopic sinus surgery for chronic rhinosinusitis. Int Forum Allergy Rhinol. 2013; 3: 788–794. 5Soy FK, Pinar E, Imre A, Calli C, Calli A, Oncel S. Histopathologic ...
Tópico(s): Allergic Rhinitis and Sensitization
2013 - Wiley | International Forum of Allergy & Rhinology
Péter Ábrányi‐Balogh, Dávid Bajusz, Zoltán Orgován, Aaron Keeley, László Petri, Nikolett Péczka, Tibor V. Szalai, Gyula Pálfy, Márton Gadanecz, Emma K. Grant, Tı́mea Imre, Tamás Takács, Ivan Ranđelović, Marcell Baranyi, András Marton, Gitta Schlosser, Qirat F. Ashraf, Elvin D. de Araujo, Tamás Karancsi, László Buday, József Tóvári, András Perczel, Jacob T. Bush, György M. Keserű,
Fragment screening is a popular strategy of generating viable chemical starting points especially for challenging targets. Although fragments provide a better coverage of chemical space and they have typically higher chance of binding, their weak affinity necessitates highly sensitive biophysical assays. Here, we introduce a screening concept that combines evolutionary optimized fragment pharmacophores with the use of a photoaffinity handle that enables high hit rates by LC-MS-based detection. The ...
Tópico(s): Chemical Synthesis and Analysis
2024 - Nature Portfolio | Communications Chemistry