Henrike M. Hamer, Daisy Jonkers, Ingrid B. Renes, Steven Vanhoutvin, Andrea Kodde, Freddy J. Troost, Koen Venema, Robert J. Brummer,
Introduction The colonic mucus layer plays an important role in the protection of the intestinal epithelium and mainly consists of mucin glycoproteins (primarily MUC2 in the colon) trefoil factor 3 (TFF3) and secretory IgA. Butyrate is a major end product of fermentation of dietary fibres and is associated with beneficial effects on colonic health. Earlier in-vitro and animal studies showed that butyrate modulates MUC2 and TFF3 expression and mucin secretion, although data from human studies are not ...
Tópico(s): Infant Nutrition and Health
2010 - Lippincott Williams & Wilkins | European Journal of Gastroenterology & Hepatology
F.M. Cornelis, Silvia Monteagudo, Laura-An Guns, Wouter den Hollander, Rob G. H. H. Nelissen, L. Storms, Tine Peeters, Ilse Jonkers, Ingrid Meulenbelt, Rik Lories,
Osteoarthritis is the most common joint disorder with increasing global prevalence due to aging of the population. Current therapy is limited to symptom relief, yet there is no cure. Its multifactorial etiology includes oxidative stress and overproduction of reactive oxygen species, but the regulation of these processes in the joint is insufficiently understood. We report that ANP32A protects the cartilage against oxidative stress, preventing osteoarthritis development and disease progression. ANP32A ...
Tópico(s): Osteoarthritis Treatment and Mechanisms
2018 - American Association for the Advancement of Science | Science Translational Medicine
Enrico Martin, Nayan Lamba, Uta Flucke, Cornelis Verhoef, J. Henk Coert, Yvonne M.H. Versleijen‐Jonkers, Ingrid M.E. Desar,
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas. Once metastasized, prognosis is poor despite regular treatment with conventional cytotoxic drugs. This study reviews the preclinical and clinical results of non-cytotoxic systemic therapy in MPNST. A systematic search was performed in PubMed and Embase databases according to the PRISMA guidelines. Search terms related to 'MPNST', 'targeted therapy', 'immunotherapy', and 'viral therapy' were used. Only in vivo studies ...
Tópico(s): Multiple Myeloma Research and Treatments
2019 - Elsevier BV | Critical Reviews in Oncology/Hematology
Charlotte H. Bruner, Stella Chipasula, Frank M. Chipasula,
... Jeni Couzyn, Ingrid de Kok, Amelia Blossom Pegram, Ingrid Jonker, Lindiwe Mabuza, Zindzi Mandela, Gcina Mhlophe, Phumzile ZuluZimbabwe: ...
Tópico(s): African history and culture studies
1995 - University of Oklahoma | World Literature Today
Matthew P. Fox, Rebecca Berhanu, Kim Steegen, Cindy Firnhaber, Prudence Ive, David Spencer, Sello Mashamaite, Sadiyya Sheik, Ingrid Jonker, Pauline Howell, Lawrence Long, Denise Evans,
Abstract Objective In resource‐limited settings, where genotypic drug resistance testing is rarely performed and poor adherence is the most common reason for treatment failure, programmatic approaches to handling treatment failure are essential. This study was performed to describe one such approach to adherence optimisation. Methods This was a single‐arm study of patients on second‐line protease inhibitor ( PI )‐based antiretroviral therapy ( ART ) with a HIV ‐1 RNA ≥400 copies/ml in Johannesburg, South ...
Tópico(s): HIV Research and Treatment
2016 - Wiley | Tropical Medicine & International Health
... with other female poets like Elisabeth Eybers and Ingrid Jonker in Afrikaans as well as with historical figures ...
Tópico(s): Lexicography and Language Studies
2007 - Tydskrif vir Letterkunde Association | Tydskrif vir letterkunde
Daisy Jonkers, Justi Ernst, Ingrid Pladdet, Reinhold W. Stockbrügger, Wim Hameeteman,
Endoscopic removal of colorectal adenomas reduces the incidence and mortality of colorectal cancer (CRC), but follow-up surveillance is recommended. Compliance with the Dutch surveillance guidelines and detection of neoplasia during follow-up has been evaluated in daily practice. From 1987 to 1996, 383 consecutive patients with colorectal adenomas (56.4% male, 61.8+/-11.3 years) were included and followed until December 2000. The mean follow-up was 80.5+/-42.5 months with 2.2+/-0.9 follow-up endoscopies. ...
Tópico(s): Genetic factors in colorectal cancer
2006 - Lippincott Williams & Wilkins | European Journal of Cancer Prevention
Marije E. Weidema, Yvonne M.H. Versleijen‐Jonkers, Uta Flucke, Ingrid M.E. Desar, Winette T.A. van der Graaf,
Angiosarcomas are rare malignant tumors with a heterogeneous clinical presentation and generally poor prognosis. It has been difficult to establish consistent molecular characteristics and driver events in angiosarcoma development. Oncogenic and angiogenesis-related pathways have been investigated pre-clinically and clinically with varying results. A few promising responses to checkpoint inhibitors have been described, but immunological features require further elucidation. With this review we present ...
Tópico(s): Sarcoma Diagnosis and Treatment
2019 - Elsevier BV | Critical Reviews in Oncology/Hematology
Marije E. Weidema, Uta Flucke, Winette T.A. van der Graaf, Vincent K.Y. Ho, Melissa H.S. Hillebrandt-Roeffen, Yvonne M.H. Versleijen‐Jonkers, Olga Husson, Ingrid M.E. Desar,
Angiosarcoma (AS) is a rare sarcoma of endothelial origin, arising spontaneously (primary AS) or after external damage such as radiation therapy or UV exposure (secondary AS). To date, reliable assessment of prognostic factors has proven difficult, due to disease rarity and heterogeneity of study cohorts. Although large registries provide relatively large AS patient series, these cases often lack histological confirmation. This study aimed to analyze AS prognostic factors in a large nationwide cohort ...
Tópico(s): Sarcoma Diagnosis and Treatment
2019 - Multidisciplinary Digital Publishing Institute | Cancers
Denise Evans, Sara Dahlberg, Rebecca Berhanu, Tembeka Sineke, Caroline Govathson, Ingrid Jonker, Elisabet Lönnermark, Matthew P. Fox,
Poor adherence is a main challenge to successful second-line ART in South Africa. Studies have shown that patients can re-suppress their viral load following intensive adherence counselling. We identify factors associated with failure to re-suppress on second-line ART.The study was a retrospective cohort study which included HIV-positive adults who experienced an elevated viral load ≥400 copies/ml on second-line ART between January 2013–July 2014, had completed an adherence counselling questionnaire ...
Tópico(s): Sexual function and dysfunction studies
2018 - Taylor & Francis | AIDS Care
E. J. JONKER, Peter J. J. Goossens, Ingrid HM Steenhuis, Nico Oud,
Mental health nurses are faced with an increasing number of aggressive incidents during their daily practice. The coercive intervention of seclusion is often used to manage patient aggression in the Netherlands. However, GGZ Nederland, the Dutch association of service providers for mental health and addition care, has initiated a project to decrease the number of seclusions in clinical psychiatry. A first step in this project is to gain insight into the current situation: the perceived prevalence ...
Tópico(s): Intimate Partner and Family Violence
2008 - Wiley | Journal of Psychiatric and Mental Health Nursing
The South African poets Ingrid Jonker, Antjie Krog and Ronelda S. Kamfer are part of the literary system of the Low Countries.Their introduction in the ...
Tópico(s): Literature, Politics, and Exile Studies
2013 - Tydskrif vir Letterkunde Association | Tydskrif vir letterkunde
Linda D. van Schinkel, Maria A. Sleddering, Mirjam A. Lips, Jacqueline T. Jonker, Albert de Roos, Hildo J. Lamb, Ingrid M. Jazet, Hanno Pijl, Johannes W. A. Smit,
Cardiac ectopic fat depositions are thought to play a role in the pathogenesis of cardiovascular disease (CVD), the main cause of death in patients with type 2 diabetes. Diet-induced weight loss results in a decrease in cardiac ectopic fat stores, however if this is the same for surgically induced weight loss is less clear. Therefore, we assessed myocardial triglyceride (TG) content, pericardial fat and cardiac function in obese patients with insulin-dependent type 2 diabetes before and 16 weeks after ...
Tópico(s): Cardiovascular Health and Disease Prevention
2014 - Wiley | Clinical Endocrinology
Stijn Witte, Marije E. Weidema, Suzanne E. J. Kaal, Yvonne M.H. Versleijen‐Jonkers, Uta Flucke, Winette van der Graaf, Ingrid M.E. Desar,
Epithelioid hemangioendothelioma (EHE) is an extremely rare vascular sarcoma with a very heterogeneous presentation and prognosis. We here present five cases of EHE emphasizing diversity in presentation, treatment, and prognosis. Furthermore, we present a review of the literature on EHE treatment options.
Tópico(s): Sarcoma Diagnosis and Treatment
2021 - Elsevier BV | Seminars in Oncology
... in a living world: The conversation about Ingrid Jonker on Instagram. Ingrid Jonker is a legend in Afrikaans literature who is ...
Tópico(s): Language, Metaphor, and Cognition
2022 - AOSIS | Literator
Jacqueline T. Jonker, Marieke Snel, Sebastiaan Hammer, Ingrid M. Jazet, R.W. van der Meer, Hanno Pijl, A. Edo Meinders, Albert de Roos, Johannes W. A. Smit, Johannes A. Romijn, Hildo J. Lamb,
Tópico(s): Advanced MRI Techniques and Applications
2013 - Springer Science+Business Media | The International Journal of Cardiovascular Imaging
Jan Marie de Gooyer, Yvonne M.H. Versleijen‐Jonkers, Melissa H.S. Hillebrandt-Roeffen, Cathelijne Frielink, Ingrid M.E. Desar, Johannes H.W. de Wilt, Uta Flucke, Mark Rijpkema,
Abstract Myxofibrosarcoma(MFS) is the most common soft tissue sarcoma(STS) in elderly patients. Surgical resection remains the main treatment modality but tumor borders can be difficult to delineate with conventional clinical methods. Incomplete resections are a common problem and local recurrence remains a clinical issue. A technique that has shown great potential in improving surgical treatment of solid tumors is tumor targeted imaging and image-guided surgery with near-infrared fluorescence. ...
Tópico(s): Angiogenesis and VEGF in Cancer
2020 - Nature Portfolio | Scientific Reports
Marike E. de Boer, Cees M.P.M. Hertogh, Rose‐Marie Dröes, Ingrid I. Riphagen, Cees Jonker, Jan A. Eefsting,
Among the general public there is a deep fear of developing dementia, which has led to an increasing number of people "at risk" seeking ways (such as advance directives) to avoid undergoing progressive mental decline. The views of people with dementia are vital in obtaining a real answer to the question of how the disease affects people's lives and whether it actually involves the suffering that so many fear.A review of the international literature is provided on what is known about living through ...
Tópico(s): Aging, Elder Care, and Social Issues
2007 - Cambridge University Press | International Psychogeriatrics
... te soek. Mirror images in the work of Ingrid Jonker and Sylvia Plath Writing poetry has an element ...
Tópico(s): Language, Metaphor, and Cognition
2008 - AOSIS | Literator
Mirror images in the work of Ingrid Jonker and Sylvia Plath Writing poetry has an element of healing in it, but how does it work? Plath and Jonker continually wrote ...
Tópico(s): Language, Metaphor, and Cognition
2008 - AOSIS | Literator
... sneeu. Die liefdesbriewe van Andre P. Brink en Ingrid Jonker Book Author: Francis Galloway (red.) Kaapstad: Umuzi, 2015. ...
Tópico(s): Legal Issues in South Africa
2016 - Tydskrif vir Letterkunde Association | Tydskrif vir letterkunde
... of the South African writers André Brink and Ingrid Jonker. Events around the entry of the letters into ...
Tópico(s): Hermeneutics and Narrative Identity
2020 - Taylor & Francis | a/b Auto/Biography Studies
2008 - Taylor & Francis | Scrutiny2
... oceanic symbolism in the poetry of Karin Boye, Ingrid Jonker and Sylvia Plath. Freud’s “oceanic feeling” is ...
Tópico(s): Religious Studies and Spiritual Practices
2008 - AOSIS | Literator
Click to increase image sizeClick to decrease image size JESSICA MURRAYUniversity of South Africa© 2014 Jessica Murray
Tópico(s): South African History and Culture
2014 - Taylor & Francis | South African Historical Journal
This book belongs to the Ohio Short Histories of Africa series. The series is designed to offer brief introductions to a range of decisive subjects in South African history, culture and politics, c...
2015 - Taylor & Francis | Journal of Southern African Studies
Tydskrif vir Letterkunde is an online, peer-reviewed, accredited scholarly journal which publishes original, previously unpublished research and overview articles on theoretical, applied or comparative aspects of African literatures and cultural practices.
Tópico(s): Lexicography and Language Studies
2016 - Tydskrif vir Letterkunde Association | Tydskrif vir letterkunde
Tópico(s): Comparative and International Law Studies
2019 - | Revista Universidad de Antioquia
Subodh Verma, Deepak L. Bhatt, Philippe Gabríel Steg, Michael Miller, Eliot A. Brinton, Terry A. Jacobson, Nitish K. Dhingra, Steven B. Ketchum, Rebecca A. Juliano, Lixia Jiao, Ralph T. Doyle, Craig Granowitz, C. Michael Gibson, Duane S. Pinto, Robert P. Giugliano, Matthew J. Budoff, R. Preston Mason, Jean‐Claude Tardif, Christie M. Ballantyne, Deepak L. Bhatt, Christie M. Ballantyne, Eliot A. Brinton, Terry A. Jacobson, Michael Miller, Philippe Gabríel Steg, Jean‐Claude Tardif, Fabrice M.A.C. Martens, Astrid Schut, Brian Olshansky, Mina K. Chung, Al Hallstrom, Lesly A. Pearce, Cyrus R. Mehta, Rajat Mukherjee, C. Michael Gibson, Anjan Chakrabarti, Eli V. Gelfand, Robert P. Giugliano, Megan Carroll Leary, Duane S. Pinto, Yuri B. Pride, Steven Ketchum, Ramakrishna Bhavanthula, G. H. Chester, Christina Copland, Katelyn Diffin, Ralph T. Doyle, K. H. Erz, Alex Giaquinto, Paula Glanton, Angela Granger, Craig Granowitz, Richard H. Iroudayassamy, Lixia Jiao, Rebecca A. Juliano, James Jin, Dimitry Klevak, Hardik Panchal, Robert Wang, Shin-Ru Wang, G Abate, Peggy J. Berry, Rene A. Braeckman, Declan Doogan, Anne Elson, Amy HauptmannBaker, Isabel Lamela, Catherine A Lubeck, Mehar S. Manku, Sabina A. Murphy, Monica Sanford, William G. Stirtan, Paresh N. Soni, Arnaud Bastien, Demetria Foster, Evangelito Gascon, Judith Johnson, Lasbert Latona, Gang Liu, Sandra M. Palleja, N. San-Juan, JiaHao Shi, William Stager, Mukund Venkatakrishnan, Ahmed YoussefAgha, Julie Zhu, Leela Aertker, S. Ankolekar, Lisa Goldberg, Natasa Rajicic, Jianfen Shu, Heng Zou, Magdy S. Mikhail, Gamil Dawood, N. MATHEW KOSHY, Sandip Mukherjee, Rafik Abadier, Andrea Lawless, William P. McGuinn, Howard Weintraub, Kathryn Rohr, Edmund Claxton, Robert Weiss, Terry D. Klein, Mani Nallasivan, Stephen T. Crowley, Marilyn King, Anthony D. Alfieri, David Fitz-Patrick, Irving K. Loh, Nolan Mayer, Rakesh Prashad, S. Lederman, Debra F. Weinstein, Harold Bays, Keith Chu, Alireza Maghsoudi, P. D. Thompson, Jeff Carstens, Anna Chang, Ken Cohen, Julius Dean, Howard Ellison, Bernard Erickson, Enrique A. Flores, Daniel W. Gottlieb, Paul Grena, John R. Guyton, Peter H. Jones, John Joseph, Norman E. Lepor, Sam Lerman, Robert D. Matheney, Theodore R. Pacheco, Michael B. Russo, John Rubino, Edward Pereira, Albert A. Seals, Eduardo Viera, Alan D. Steljes, Jason D. Thompson, Shaival Kapadia, Michael McIvor, Jorge E. Salazar, Jose O. Santiago, Ralph Vicari, Martin R. Berk, William A. Kaye, Marcus E. McKenzie, David Podlecki, Brian D. Snyder, Stephen Nash, David M. Herrington, Wallace Johnson, Joseph R. Lee, Ronald Blonder, Alpa M. Patel, Ramón Castelló, Susan Greco, Larry S. Dean, Venkatesh Nadar, Mark A. Nathan, Ranganatha P. Potu, Robert Sangrigoli, Richard W. Smalling, Mitchell Davis, Robert Braastad, James W. McCriskin, Kunal Bodiwala, Joe Hargrove, Mark Graves, George Emlein, Raegan W. Durant, James W. Clower, Rohit Arora, Narendra Singh, Lisa W. Martin, W. Herbert Haught, Marc P. Litt, Michael D. Klein, Peter Hoagland, Michael Goldstein, Marco Mazzella, Daniel H. Dunker, Brian H. Kahn, Carlos S. Ince, Frank McGrew, Lee Jc, David Pan, Salman Khan, Uri Elkayam, Wasim Deeb, Anne C. Goldberg, Christopher Brown, Wayne Leimbach, Thomas S. Backer, David Sutton, Matthew J. Budoff, Joel Gellman, Anu R. George, Alan S. Hoffman, Mark Kates, Kishlay Anand, Robert A. Bear, B Cavanaugh, Ramon G. Reyes, Rodolfo Sotolongo, Kenneth Sabatino, Kevin Gallagher, Ehab Sorial, Chris Geohas, Kathleen Magness, Bernard Grunstra, Frederik A. Martin, William S. Knapp, Mel E. Lucas, John J. Champlin, Jason Demattia, Patrick H. Peters, Judith Kirstein, William J. Randall, Cezar Staniloae, Jennifer G. Robinson, A. Adler, Christopher Case, Andrew J. Kaplan, Gregory F. Lakin, Krishan K. Goyle, Michael J. DiGiovanna, Chester Fisher, Michael Lillestol, Michael R. Robinson, Robert G. Perry, Lawrence S. Levinson, Brian G. Everhart, Robert D. Madder, Earl F. Martin, Earl E. Martin, Imtiaz Alam, Jose Mari L. Elacion, Robina Poonawala, Taddese T. Desta, Jerome A. Robinson, Gilbert J. Martinez, Jakkidi Reddy, Jeffrey D. Wayne, Samuel Mujica Trenche, Westbrook I. Kaplan, Rubin H. Saavedra, Michael D. DiGregorio, Barry Bertolet, Neil J. Fraser, Terence T. Hart, Ronald J. Graf, David Jasper, Michael Dunn, Dan Streja, David J. Strobl, Nan Jiang, Vicki Kalen, Richard Mascolo, Mercedes B. Samson, Michael C. Stephens, Bret M. Bellard, Mario Juarez, Patrick J. McCarthy, John Checton, Michael Stillabower, Edward Goldenberg, Amin H. Karim, Naseem Jaffrani, Robert C. Touchon, Erich R. Fruehling, Clayton J. Friesen, Pradipta Chaudhuri, Frank H. Morris, Robert Broker, Rajesh Patel, Susan Hole, R Miller, Francisco G. Miranda, Sadia Dar, S Gentry, Paul Hermany, Charles B. Treasure, Miguel E. Trevino, R Villacorta Acosta, Anthony J. Japour, Samuel J. Durr, Thomas J. Wang, Om P Ganda, Perry Krichmar, James L. Arter, Douglas Jacoby, Michael Schwartz, Amer Al‐Karadsheh,
Despite advances in surgery and pharmacotherapy, there remains significant residual ischemic risk after coronary artery bypass grafting surgery. In REDUCE-IT (Reduction of Cardiovascular Events With Icosapent Ethyl-Intervention Trial), a multicenter, placebo-controlled, double-blind trial, statin-treated patients with controlled low-density lipoprotein cholesterol and mild to moderate hypertriglyceridemia were randomized to 4 g daily of icosapent ethyl or placebo. They experienced a 25% reduction ...
Lippincott Williams & Wilkins
... of symbolism in the poetry of Karin Boye, Ingrid Jonker and Sylvia Plath. Freud's oceanic feeling is ... die seesimboliek in die poesie van Karin Boye, Ingrid Jonker en Sylvia Plath, Freud se oseaanbelewenis word beskryf ... n simboliese vlak, deur die digters Karen Boye, Ingrid Jonker en Sylvia Plath te vergelyk. Volgens Jung is ...
Tópico(s): Language, Metaphor, and Cognition
2008 - AOSIS | Literator