Limpar
1.388 resultados

Acesso aberto

Tipo do recurso

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Artigo Revisado por pares

Claudio Gerbaldi, Matteo Destro, Jijeesh Ravi Nair, Stefania Ferrari, Irene Quinzeni, Eliana Quartarone,

An innovative V2O5 based multiphase electrode/electrolyte composite is prepared by a fast, versatile and easily scalable UV-induced free-radical photo-polymerisation technique and its electrochemical properties are thoroughly investigated. The compact configuration consists of a highly conducting methacrylic-based polymer electrolyte directly formed over a r.f. sputtered V2O5 thin film positive electrode. All-solid state thin-film Li and Li-ion cells are assembled by simply contacting the polymeric ...

Tópico(s): Advanced Battery Technologies Research

2013 - Elsevier BV | Nano Energy

Artigo Revisado por pares

Stefania Grimaldi, Irene Angeluccetti, Velio Coviello, Paolo Vezza,

Abstract In the Sahelian region, the high precipitation intensity and the daily rainfall extreme values are currently the main cause of soil erosion and land degradation. In addition, solid transport often leads to reservoir siltation and reduction of the amount of water available for agriculture. To cope with these issues, Soil and Water Conservation (SWC) measures have been regularly employed in the Sahelian area. However, a proper cost‐effectiveness analysis of the impact of SWC interventions ...

Tópico(s): Hydrology and Sediment Transport Processes

2013 - Wiley | Land Degradation and Development

Revisão Revisado por pares

Stefania Corti, Irene Faravelli, Marina Cardano, Luciano Conti,

Introduction: Although intensive efforts have been made, effective treatments for neurodegenerative and neurodevelopmental diseases have not been yet discovered. Possible reasons for this include the lack of appropriate disease models of human neurons and a limited understanding of the etiological and neurobiological mechanisms. Recent advances in pluripotent stem cell (PSC) research have now opened the path to the generation of induced pluripotent stem cells (iPSCs) starting from somatic cells, thus ...

Tópico(s): Neuroscience and Neural Engineering

2015 - Taylor & Francis | Expert Opinion on Drug Discovery

Artigo Acesso aberto Revisado por pares

Paolo Carrega, Fabrizio Loiacono, Emma Di Carlo, Angelo Scaramuccia, Marco Mora, Romana Conte, Roberto Benelli, Grazia Maria Spaggiari, Claudia Cantoni, Stefania Campana, Irene Bonaccorsi, Barbara Morandi, Mauro Truini, Maria Cristina Mingari, Lorenzo Moretta, Guido Ferlazzo,

Tertiary lymphoid structures (TLSs) are a common finding in non-small cell lung cancer (NSCLC) and are predictors of favourable clinical outcome. Here we show that NCR+ innate lymphoid cell (ILC)-3 are present in the lymphoid infiltrate of human NSCLC and are mainly localized at the edge of tumour-associated TLSs. This intra-tumoral lymphocyte subset is endowed with lymphoid tissue-inducing properties and, on activation, produces IL-22, TNF-α, IL-8 and IL-2, and activates endothelial cells. Tumour ...

Tópico(s): Eosinophilic Esophagitis

2015 - Nature Portfolio | Nature Communications

Artigo Revisado por pares

Stefania Casella, Irene Vazzana, Elisabetta Giudice, Francesco Fazio, Giuseppe Piccione,

The changes of cortisol, red blood cells (RBC), hemoglobin (Hb), hematocrit (Hct), heart rate (HR), respiratory rate (RR) and rectal temperature (RT) were evaluated after a reining training session in eight Quarter Horses. All parameters were measured before exercise (T0), immediately after exercise (T1), 1 h after exercise (T2), 2 h after exercise (T3) and 24 h after exercise (T4). One-way analysis of variance (ANOVA) for repeated measures, followed Bonferroni's post hoc test, showed a significant effect of ...

Tópico(s): Effects of Environmental Stressors on Livestock

2015 - Wiley | Animal Science Journal

Artigo Revisado por pares

Emanuele Cozzani, Arianna Fay Agnoletti, Stefania Speziari, Irene Schiavetti, Mirca Zotti, A Persi, Francesco Drago, Aurora Parodi,

To identify the prevalence of onychomycosis and epidemiological features in older adults (>65%) with toenail onychodystrophy. In particular, the aim of the study was to analyze risk factors/protective factors, clinical manifestations, comorbidities and etiological agents.A prospective study was carried out from February 2012 to May 2012 at San Martino-IST of Genoa, Italy. The inclusion criteria for enrolment were the presence of onychodystrophy of one or more toenails and age >65 years. The exclusion ...

Tópico(s): Plant Pathogens and Fungal Diseases

2015 - Wiley | Geriatrics and gerontology international/Geriatrics & gerontology international

Revisão Acesso aberto Revisado por pares

Cecilia Gotti, Francesco Clementi, Alice Fornari, Annalisa Gaimarri, Stefania Guiducci, Irene Manfredi, Milena Moretti, Patrizia Pedrazzi, Luca Pucci, Michèle Zoli,

Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand-gated ion channels present in the central and peripheral nervous systems, that are permeable to mono- and divalent cations. They share a common basic structure but their pharmacological and functional properties arise from the wide range of different subunit combinations making up distinctive subtypes. nAChRs are involved in many physiological functions in the central and peripheral nervous systems, and are the targets of ...

Tópico(s): Receptor Mechanisms and Signaling

2009 - Elsevier BV | Biochemical Pharmacology

Artigo Revisado por pares

Daniela Alberghina, Stefania Casella, Irene Vazzana, Vincenzo Ferrantelli, Claudia Giannetto, Giuseppe Piccione,

Electrophoretic patterns of serum proteins provide useful information on pathological conditions in ruminants. Their reference values, however, are dissimilar to those of other species. Reference values for goats using agarose gel as the supporting matrix have not been reported.The aim of this study was to evaluate serum concentrations of total protein and protein fractions (albumin and globulins) by means of agarose gel electrophoresis (AGE) in goats in order to establish electrophoretic reference ...

Tópico(s): Animal Virus Infections Studies

2010 - Wiley | Veterinary Clinical Pathology

Artigo Revisado por pares

Roberta Maggio, Nadia Peragine, Elisabetta Calabrese, Maria Stefania De Propris, Stefania Intoppa, Irene Della Starza, Cristina Ariola, Antonella Vitale, Robin Foà, Anna Guarini,

The capacity to generate effective dendritic cells (DC) from adult acute lymphoblastic leukemia (ALL) patients in complete remission (CR) and off-therapy was investigated. Monocyte-derived DC cultured in the presence of granulocyte-macrophage colony-stimulating factor, interleukin (IL)-4 and tumor necrosis factor (TNF)-α expressed maturation markers, produced IL-12 and loaded apoptotic bodies to a similar extent to normal DC. Patients' circulating T and NK lymphocytes were normally represented and, after ...

Tópico(s): Immune Cell Function and Interaction

2007 - Taylor & Francis | Leukemia & lymphoma/Leukemia and lymphoma

Artigo Acesso aberto Revisado por pares

Anna Guerra, Maria Rosaria Sapio, Vincenzo Marotta, Elisabetta Campanile, Stefania Rossi, Irene Forno, Laura Fugazzola, Alfredo Budillon, Tania Moccia, Gianfranco Fenzi, Mario Vitale,

BRAFV600E is considered a primary event, a negative prognostic marker, and a site for pharmacological intervention in papillary thyroid carcinoma (PTC). We asked whether BRAFV600E can occur as a subclonal event in PTC and whether this and other oncogenes can coexist in the same tumor. We determined by pyrosequencing the percentage of mutant BRAF, NRAS, and KRAS alleles in a series of conventional PTC. We also analyzed the BRAF mutation status in PTC cell clones in culture. BRAFV600E alleles were ...

Tópico(s): S100 Proteins and Annexins

2011 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism

Artigo Acesso aberto Revisado por pares

Emanuela Turillazzi, Gabriele Di Giammarco, Margherita Neri, Stefania Bello, Irene Riezzo, Vittorio Fineschi,

Abstract Aortic valve replacement (AVR) is the gold standard for the treatment of severe symptomatic aortic stenosis. Complications directly related to surgical procedure are relatively infrequent. Coronary ostial stenosis is, generally, referred as late complication. Anecdotal reports concern coronary ostial stenosis as acute complication. A unique fatal case of intraoperative, bilateral coronary ostial obstruction by prosthetic valve leading to an extensive myocardial infarction is reported. Surgeons ...

Tópico(s): Coronary Artery Anomalies

2011 - BioMed Central | Diagnostic Pathology

Artigo Revisado por pares

V. Cozzi, Cecília Garlanda, Manuela Nebuloni, Virginia Maina, A. Martinelli, Stefania Calabrese, Irene Cetin,

Endothelial dysfunction typical of preeclampsia (PE) is the result of an excessive maternal inflammatory response to pregnancy. We investigated PTX3 in maternal, fetal and placental compartments in complicated pregnancies. Maternal blood samples were collected during the third trimester in 53 PE, 43 IUGR (intrauterine growth restriction) and 50 normal pregnancies. Fetal samples were collected from the umbilical vein in 26 PE, 23 IUGR and 26 normal pregnancies at elective cesarean section. Pattern ...

Tópico(s): Circular RNAs in diseases

2012 - Elsevier BV | Placenta

Artigo Acesso aberto Revisado por pares

Serena Vinci, Stefania Gelmini, Irene Mancini, Francesca Malentacchi, Mario Pazzagli, Cristina Beltrami, Pamela Pinzani, Claudio Orlando,

Studies on miRNA profiling revealed that a large number of them are significantly deregulated in human cancers. The molecular mechanisms of this deregulation are not totally clarified, even if genetics and epigenetics are frequently involved. Single nucleotide polymorphisms (SNPs) are the most common type of genetic variation in the human genome. A SNP into miRNA gene might affect the transcription of primary miRNA, its processing and miRNA-mRNA interaction. We investigated the distribution of sequence ...

Tópico(s): Circular RNAs in diseases

2012 - Elsevier BV | Methods

Artigo Revisado por pares

Maria‐Beatrice Coltelli, Stefania Savi, Irene Della Maggiore, Vincenzo Liuzzo, Mauro Aglietto, Francesco Ciardelli,

Abstract Summary: The effect of metal catalysts in promoting the formation of the comb copolymer between a very low density polyethylene (VLDPE) grafted with diethyl maleate and PET has been studied in this paper following a model study based on low molecular weight molecules resembling the local structure of the reactive groups in the reference macromolecules. Ti(OBu) 4 was used as the catalyst and the reactions were carried out under the same conditions as in the case of the macromolecules species. ...

Tópico(s): Polymer Nanocomposites and Properties

2004 - Wiley | Macromolecular Materials and Engineering

Revisão Revisado por pares

Paolo Carrega, Stefania Campana, Irene Bonaccorsi, Guido Ferlazzo,

The recent appreciation of novel subsets of innate lymphoid cells (ILCs) as important regulators of tissue homeostasis, inflammation and repair, raise questions regarding the presence and role of these cells in cancer tissues. In addition to natural killer and fetal lymphoid tissue inducer (LTi) cells, the ILC family comprises non-cytolytic, cytokine-producing cells that are classified into ILC1, ILC2 and ILC3 based on phenotypic and functional characteristics. Differently from natural killer cells, ...

Tópico(s): Eosinophilic Esophagitis

2016 - Elsevier BV | Immunology Letters

Artigo Acesso aberto Revisado por pares

Giovanni Dedenaro, Stefania Costa, Irene Rugiero, Paola Pedrini, Elena Tamburini,

Global interest towards lactic acid production has recently significantly increased because lactic acid can be used as raw material for the production of polylactic acid (PLA), a polymer used in biodegradable plastics for its special, environmentally-friendly properties. However, the high production costs have hindered the large-scale application of PLA due to the high price of lactic acid. Here we evaluated the potential of pear pomace and ricotta cheese whey (RCW) as a low-cost source of nutrients ...

Tópico(s): Microbial Metabolic Engineering and Bioproduction

2016 - Multidisciplinary Digital Publishing Institute | Applied Sciences

Artigo Acesso aberto Revisado por pares

Marco Siano, Francesca Molinari, Vittoria Martin, Nicolas Mach, Martin Früh, Stefania Freguia, Irene Corradino, Michele Ghielmini, Milo Frattini, Vittoria Espeli,

Abstract Lessons Learned Panitumumab shows activity in terms of disease control rate and preventing disease progression but not for tumor shrinkage in head and neck squamous cell cancer for second-line treatment. Epidermal growth factor receptor (EGFR) copy number gain, a property of tumor cells that theoretically could identify patients more likely to experience disease response, was common among patients having disease control. Our trial, given the lower toxicity with an every-2-week schedule, ...

Tópico(s): Colorectal Cancer Treatments and Studies

2017 - AlphaMed Press | The Oncologist

Artigo Acesso aberto Revisado por pares

Stefania Zimbone, Irene Monaco, Fiorenza Gianì, Giuseppe Pandini, Agata Copani, Maria Laura Giuffrida, Enrico Rizzarelli,

Summary Alzheimer's disease ( AD ) is a progressive neurodegenerative disorder associated with synaptic dysfunction, pathological accumulation of β‐amyloid (Aβ), and neuronal loss. The self‐association of Aβ monomers into soluble oligomers seems to be crucial for the development of neurotoxicity ( J. Neurochem ., 00, 2007 and 1172). Aβ oligomers have been suggested to compromise neuronal functions in AD by reducing the expression levels of the CREB target gene and brain‐derived neurotrophic factor ( BDNF ) ( J. ...

Tópico(s): Alzheimer's disease research and treatments

2017 - Wiley | Aging Cell

Artigo Acesso aberto Revisado por pares

Elena Tamburini, Stefania Costa, Irene Rugiero, Paola Pedrini, Maria Gabriella Marchetti,

A great interest has recently been focused on lycopene and β-carotene, because of their antioxidant action in the organism. Red-flesh watermelon is one of the main sources of lycopene as the most abundant carotenoid. The use of near-infrared spectroscopy (NIRS) in post-harvesting has permitted us to rapidly quantify lycopene, β-carotene, and total soluble solids (TSS) on single intact fruits. Watermelons, harvested in 2013-2015, were submitted to near-infrared (NIR) radiation while being transported ...

Tópico(s): Essential Oils and Antimicrobial Activity

2017 - Multidisciplinary Digital Publishing Institute | Sensors

Artigo Acesso aberto Revisado por pares

Elena Ricci, S Noli, Stefania Ferrari, Irene La Vecchia, Sonia Cipriani, Valentina De Cosmi, Edgardo Somigliana, Fabio Parazzini,

Summary Background The association between alcohol intake and male reproductive function is still controversial. In the frame of a prospective cohort study , designed to investigate the relation between life style and fertility, we performed a cross‐sectional analysis of semen quality. Methods Men of subfertile couples , referring to an Italian Infertility Unit and eligible for assisted reproductive techniques ( ART s), were asked about their lifestyle: BMI , smoking, caffeine intake, occupational and leisure ...

Tópico(s): Reproductive Biology and Fertility

2018 - Wiley | Andrology

Artigo Acesso aberto Revisado por pares

Stefania Santoro, Irene Pluchinotta, Alessandro Pagano, Polona Pengal, Blaž Cokan, Raffaele Giordano,

Evidences from flood risk management demonstrated that a deep understanding of the main physical phenomena to be addressed is often not enough but should be also integrated with stakeholders' knowledge and risk perception. Particularly, the effectiveness of flood risk management strategies is highly dependent on stakeholders' perception and attitudes, which play a critical role on how individuals and institutions act to mitigate risks. Furthermore, practitioners and policy-makers realized that grey ...

Tópico(s): Multi-Criteria Decision Making

2018 - Elsevier BV | The Science of The Total Environment

Artigo Acesso aberto Revisado por pares

Stefania Costa, Irene Rugiero, Christian Larenas Uría, Paola Pedrini, Elena Tamburini,

Valuable biomass conversion processes are highly dependent on the use of effective pretreatments for lignocellulose degradation and enzymes for saccharification. Among the nowadays available treatments, chemical delignification represents a promising alternative to physical-mechanical treatments. Banana is one of the most important fruit crops around the world. After harvesting, it generates large amounts of rachis, a lignocellulosic residue, that could be used for second generation ethanol production, ...

Tópico(s): Advanced Cellulose Research Studies

2018 - Multidisciplinary Digital Publishing Institute | Biomolecules

Artigo Revisado por pares

Nico Leupold, Konstantin Schötz, Stéfania Cacovich, Irene Bauer, Maximilian Schultz, Monika Daubinger, Leah Kaiser, Amelle Rebaï, Jean Rousset, Anna Köhler, Philip Schulz, Ralf Moos, Fabian Panzer,

We show that mechanochemically synthesized halide perovskite powders from a ball milling approach can be employed to fabricate a variety of lead halide perovskites with exceptional intrinsic stability. Our MAPbI3 powder exhibits higher thermal stability than conventionally processed thin films, without degradation after more than two and a half years of storage and only negligible degradation after heat treatment at 220 °C for 14 h. We further show facile recovery strategies of nonphase-pure powders ...

Tópico(s): Quantum Dots Synthesis And Properties

2019 - American Chemical Society | ACS Applied Materials & Interfaces

Revisão Acesso aberto Revisado por pares

Gianluca Costamagna, Luca Andreoli, Stefania Corti, Irene Faravelli,

Induced pluripotent stem cells (iPSCs)-based two-dimensional (2D) protocols have offered invaluable insights into the pathophysiology of neurological diseases. However, these systems are unable to reproduce complex cytoarchitectural features, cell-cell and tissue-tissue interactions like their in vivo counterpart. Three-dimensional (3D)-based culture protocols, though in their infancy, have offered new insights into modeling human diseases. Human neural organoids try to recapitulate the cellular diversity ...

Tópico(s): Neurogenesis and neuroplasticity mechanisms

2019 - Multidisciplinary Digital Publishing Institute | Cells

Artigo Acesso aberto Revisado por pares

Francesco Dionisi, Stefania Croci, Irene Giacomelli, Marco Cianchetti, A. Caldara, M. Bertolin, V. Vanoni, Riccardo Pertile, L. Widesott, Paolo Farace, Marco Schwarz, Maurizio Amichetti,

Background and purpose: Recurrent nasopharyngeal carcinoma (NPC) has limited curative treatment options. Reirradiation is the only potential definitive treatment in advanced stages at a cost of substantial severe and often life-threatening toxicity. Proton therapy (PT) reduces irradiated volume compared with X-ray radiotherapy and could be advantageous in terms of safety and efficacy in a population of heavily pretreated patients. We report the retrospective results of PT reirradiation in recurrent ...

Tópico(s): Head and Neck Cancer Studies

2019 - Taylor & Francis | Acta Oncologica

Artigo Acesso aberto Revisado por pares

Stefania Paolucci, Irene Cassaniti, Federica Novazzi, L Fiorina, Antonio Piralla, Giuditta Comolli, Raffaele Bruno, Renato Maserati, Roberto Gulminetti, Stefano Novati, Francesco Mojoli, Fausto Baldanti, Raffaele Bruno, Mario U. Mondelli, Enrico Brunetti, Angela Di Matteo, Elena Seminari, Laura Maiocchi, Valentina Zuccaro, Layla Pagnucco, B Mariani, Serena Ludovisi, Raffaella Lissandrin, Antonio Parisi, Paolo Sacchi, SFA Patruno, G Michelone, Roberto Gulminetti, Domenico Zanaboni, Stefano Novati, Renato Maserati, P Orsolini, Marco Vecchia, Marco Sciarra, Erika Asperges, Marta Colaneri, Di Filippo A, Margherita Sambo, Simona Biscarini, Matteo Lupi, Silvia Roda, T.C. Pieri, Ilaria Gallazzi, Michele Sachs, P. Valsecchi, Stefano Perlini, C Alfano, Marco Bonzano, Domenica Federica Briganti, Giuseppe Crescenzi, A.G. Falchi, Roberta Guarnone, Barbara Katia Guglielmana, Enrico Maggi, Ilaria Martino, Pietro Pettenazza, Serena Pioli di Marco, Francesca Maria Quaglia, Anna Sabena, Francesco Salinaro, Francesco Speciale, Ilaria Zunino, M De Lorenzo, Gioel Gabrio Secco, L. Dimitry, Giovanni Cappa, Igor Maisak, Benedetta Chiodi, M. Sciarrini, Bruno Barcella, Flavia Resta, Luca Moroni, Giulia Vezzoni, Lorenzo Scattaglia, Enrico Boscolo, Caterina Zattera, MF Tassi, Vincenzo Capozza, Damiano Vignaroli, Marco Bazzini, Giorgio Antonio Iotti, Francesco Mojoli, Mirko Belliato, Luciano Perotti, Silvia Mongodi, Guido Tavazzi, Gian Luigi Marseglia, Amelia Licari, Ilaria Brambilla, Daniela Barbarini, Antonio Bruno, Patrizia Cambieri, Giulia Campanini, C. Cavanna, Giuditta Comolli, Marta Corbella, R. Daturi, Milena Furione, B Mariani, P. Marone, Renato Maserati, E. Monzillo, Stefania Paolucci, M. Parea, Elena Percivalle, Antonio Piralla, Francesca Rovida, Antonella Sarasini, Maurizio Zavattoni, G. Adzasehoun, Marco Vittorio Rossi Ardizzone, Laura Bellotti, Vincenzo Brunco, Ermanna Cabano, Gianluca Casali, L Capella, D Devitis, Luca Dossena, G Frisco, G. Garbagnoli, F Gardellini, Alessia Girello, A Guerrizio, V. Landini, C. Lucchelli, V. Maliardi, Pasqua Piemontese, S. Pezzaia, María Sol Prémoli, Chiara Rebuffa, Cinzia Zanello, Jessica Bagnarino, Federica Bergami, Antonella Bonetti, G Caneva, Irene Cassaniti, Antonio Corcione, Raffaella Di Martino, Anna Napoli, Alessandro Ferrari, Guglielmo Ferrari, L Fiorina, Anna Gallone, Federica Giardina, Adriana Castello Costa Girardi, A Mercato, Cristina Merla, F Novazzi, G. Ratano, Barbara Rossi, G Saveriaempillai, I.M. Sciabica, Monica Tallarita, Edoardo Vecchio Nepita, Julian Vitali, Antonella Cerino, Stefania Varchetta, Barbara Oliviero, Stefania Mantovani, Dalila Mele, Monica Calvi, Michele Tizzoni, Carlo Nicora, Antonio Triarico, Vincenzo Petronella, Carlo Marena, A Muzzi, Paolo Lago, Sara Cutti, Viola Novelli, Francesco Comandatore, Gherard Batisti Biffignandi, Stefano Gaiarsa, Marco Rettani, Claudio Bandi, Alessandro Ferrari,

Highlights•EBV reactivation was observed in patients with COVID-19.•NK+and CD8+T cell reduction was related to the severity of COVID-19 infection.•An increase of B cells in patients with severe symptoms was documented.AbstractObjectivesThe immunologic profile and opportunistic viral DNA increase were monitored in Italian patients with COVID-19 in order to identify markers of disease severity.MethodsA total of 104 patients infected with SARS-CoV-2 were evaluated in the study. Of them, 42/104 (40.4%) ...

Tópico(s): Parvovirus B19 Infection Studies

2020 - Elsevier BV | International Journal of Infectious Diseases

Artigo Acesso aberto Revisado por pares

Shyam Sharan Shrestha, Stefania Sut, Irene Ferrarese, Serena Barbon Di Marco, Gökhan Zengin, Michele De Franco, Deepak Raj Pant, Mohamad Fawzi Mahomoodally, Nicola Ferri, Noemi Biancorosso, Filippo Maggi, Stefano Dall’ Acqua, Sangeeta Rajbhandary,

Girardinia diversifolia, also known as Himalayan nettle, is a perennial herb used in Nepal to make fiber as well as in traditional medicine for the treatment of several diseases. To date, phytochemical studies and biological assays on this plant are scarce. Thus, in the present work, the G. diversifolia extracts have been evaluated for their potential pharmaceutical, cosmetic and nutraceutical uses. For this purpose, detailed phytochemical analyses were performed, evidencing the presence of phytosterols, ...

Tópico(s): Silymarin and Mushroom Poisoning

2020 - Multidisciplinary Digital Publishing Institute | Molecules

Artigo Acesso aberto Revisado por pares

Sarah Mosca, Giorgia Cardinali, Enrica Flori, Stefania Briganti, Irene Bottillo, Anna Maria Mileo, Vittoria Maresca,

Abstract The melanocortin‐1 receptor (MC1R) belongs to the family of the G protein‐coupled receptor (GPCR). Activated GPCRs can promote the phosphoinositide 3‐kinase (PI3K) pathway. Few studies deal with the role of the PI3K pathway activation in response to αMSH. On B16‐F10 cell line, we investigated the αMSH‐dependent modulation of pAKT/AKT, as a key element of the PI3K pathway after rapid and prolonged stimulation. We demonstrated that αMSH triggers a rapid modulation of AKT which culminates in ...

Tópico(s): Skin Protection and Aging

2020 - Wiley | Pigment Cell & Melanoma Research

Artigo Revisado por pares

Stefano Dall’Acqua, Gourav Kumar, Kouadio Ibrahime Sinan, Stefania Sut, Irene Ferrarese, Mohamad Fawzi Mahomoodally, Roumita Seebaluck-Sandoram, Ouattara Katinan Etienne, Gökhan Zengin,

In African traditional medicine Cochlospermum planchonii is used to manage various diseases such as malaria, diarrhoea, jaundice, infections and inflammation, hence presents the potential to be a good source of bioactive compounds. In this study, traditional and green extraction techniques have been used namely green extraction (homogenizer assisted extraction (HAE) and Sonication (SON)) and conventional extraction (Maceration (MAC), and Soxhlet (SOX)). Extracts prepared from aerial parts were studied ...

Tópico(s): Seed and Plant Biochemistry

2020 - Elsevier BV | Industrial Crops and Products