Ana Ramírez-Adrados, Ana Isabel Beltrán-Velasco, Cristina Gonzalez-de-Ramos, Silvia Fernández-Martínez, Beatriz Martínez‐Pascual, Valentín E. Fernández-Elías, Vicente Javier Clemente‐Suárez,
The objective of this study was to analyze the effect of final dissertation defense language in the autonomic stress response and cortical arousal of Physiotherapy students. We analysed in 110 students divided in 2 groups: native language (83) and non-native language (27), the autonomic stress response in four different moments of the dissertation defense; the cortical arousal and subjective perception of distress before and after the dissertation; and academic performance perception of students and ...
Tópico(s): Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
2020 - Elsevier BV | Physiology & Behavior
Liliana Soroceanu, Ryuichi Murase, Chandani Limbad, Eric A. Singer, Juanita Allison, Isabel Adrados, Rumi Kawamura, Arash Pakdel, Yayoi Fukuyo, Daniel Nguyen, Sabeena Khan, Robert Arauz, Garret Yount, Dan H. Moore, Pierre‐Yves Desprez, Sean D. McAllister,
Glioblastoma is the most common form of primary adult brain tumors. A majority of glioblastomas grow invasively into distant brain tissue, leading to tumor recurrence, which is ultimately incurable. It is, therefore, essential to discover master regulators that control glioblastoma invasiveness and target them therapeutically. We show here that the transcriptional regulator Id-1 plays a critical role in modulating the invasiveness of glioblastoma cell lines and primary glioblastoma cells. Id-1 expression ...
Tópico(s): Neuroblastoma Research and Treatments
2012 - American Association for Cancer Research | Cancer Research
Daniel Gómez-Cabello, Isabel Adrados, David Gamarra, Hikaru Kobayashi, Yoshihiro Takatsu, Kyoko Takatsu, Jesús Gil, Ignacio Palmero,
The regulation of gene expression by microRNAs (miRNAs) is critical for normal development and physiology. Conversely, miRNA function is frequently impaired in cancer, and other pathologies, either by aberrant expression of individual miRNAs or dysregulation of miRNA synthesis. Here, we have investigated the impact of global disruption of miRNA biogenesis in primary fibroblasts of human or murine origin, through the knockdown of DGCR8, an essential mediator of the synthesis of canonical miRNAs. We ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2013 - Wiley | Aging Cell
Isabel Adrados, Javier Larrasa-Alonso, Antonio Galarreta, Irene López‐Antona, Camino Menéndez, María Abad, Jesús Gil, Gema Moreno‐Bueno, Ignacio Palmero,
Cellular senescence is an antiproliferative response with essential functions in tumor suppression and tissue homeostasis. Here we show that SIX1, a member of the SIX family of homeobox transcriptional factors, is a novel repressor of senescence. Our data show that SIX1 is specifically downregulated in fibroblasts upon oncogenic stress and other pro-senescence stimuli, as well as in senescent skin premalignant lesions. Silencing of SIX1 in human fibroblasts suffices to trigger senescence, which ...
Tópico(s): Genomics and Chromatin Dynamics
2015 - Springer Nature | Oncogene
Spencer D. Wood, Wayne Grant, Isabel Adrados, Jun Yong Choi, James M. Alburger, Derek R. Duckett, William Roush,
We present the outcome of an in silico high throughput screen (HTS) and optimization of a small molecule Unc-51-Like Kinase 1 (ULK1) inhibitor hit, SR-17398, with an indazole core. Docking studies guided design efforts that led to inhibitors with increased activity vs ULK1 (IC50 < 50 nM). The most advanced molecules in this inhibitor series (3a and 3g) hold promise for further development into selective ULK1 molecular probes to interrogate the biology of ULK1 and to assess whether selectively targeting ...
Tópico(s): Plant-Microbe Interactions and Immunity
2017 - American Chemical Society | ACS Medicinal Chemistry Letters
Oliver Crawley, Karla J. Opperman, Muriel Desbois, Isabel Adrados, Melissa A. Borgen, Andrew C. Giles, Derek R. Duckett, Brock Grill,
Abstract Autophagy is an intracellular catabolic process prominent in starvation, aging and disease. Neuronal autophagy is particularly important, as it affects the development and function of the nervous system, and is heavily implicated in neurodegenerative disease. Nonetheless, how autophagy is regulated in neurons remains poorly understood. Using an unbiased proteomics approach, we demonstrate that the primary initiator of autophagy, the UNC-51/ULK kinase, is negatively regulated by the ubiquitin ...
Tópico(s): Ubiquitin and proteasome pathways
2019 - Nature Portfolio | Nature Communications
Vanessa Saunders, M. Lafitte, Isabel Adrados, Víctor Quereda, Daniel Feurstein, Yuanyuan Ling, Mohammad Fallahi, Laura H. Rosenberg, Derek R. Duckett,
Glioblastoma multiforme (GBM) is the most aggressive and common form of adult brain cancer. Current therapeutic strategies include surgical resection, followed by radiotherapy and chemotherapy. Despite such aggressive multimodal therapy, prognosis remains poor, with a median patient survival of 14 months. A proper understanding of the molecular drivers responsible for GBM progression are therefore necessary to instruct the development of novel targeted agents and enable the design of effective treatment ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2015 - American Society for Pharmacology and Experimental Therapeutics | Molecular Pharmacology
Pierre‐Yves Desprez, Ryuichi Murase, Chandani Limbad, Rinette W.L. Woo, Isabel Adrados, Klemens Weitenthaler, Liliana Soroceanu, Nathan Salomonis, Sean D. McAllister,
Background: We previously reported that cannabidiol (CBD), a cannabinoid with a low toxicity profile, downregulated the expression of the prometastatic gene inhibitor of DNA binding 1 (ID1) in cancer cells, leading to inhibition of tumor progression in vivo. While CBD is broadly used, including in the self-medication of cancer patients, and CBD-based therapies are undergoing clinical evaluation for cancer treatment, its mechanisms of action are still poorly understood. Methods: In this study, using ...
Tópico(s): Nuclear Receptors and Signaling
2020 - Mary Ann Liebert, Inc. | Cannabis and Cannabinoid Research
Lucia García-López, Isabel Adrados, Dolors Ferrés-Marcó, María Domínguez,
Both in situ and allograft models of cancer in juvenile and adult Drosophila melanogaster fruit flies offer a powerful means for unravelling cancer gene networks and cancer-host interactions. They can also be used as tools for cost-effective drug discovery and repurposing. Moreover, in situ modeling of emerging tumors makes it possible to address cancer initiating events-a black box in cancer research, tackle the innate antitumor immune responses to incipient preneoplastic cells and recurrent growing ...
Tópico(s): Invertebrate Immune Response Mechanisms
2021 - Multidisciplinary Digital Publishing Institute | Cells
Daniel Gómez-Cabello, Isabel Adrados, Ignacio Palmero,
Cellular senescence acts as a physiological barrier against uncontrolled proliferation of cells with potentially harmful alterations, contributing to tumor suppression and tissue homeostasis in live organisms [1]. Senescence is a complex phenotype that involves major changes in cellular function and structure. This phenotype is characterized by a specific gene expression program, which is controlled by key transcriptional regulators as well as by global and gene-specific epigenetic changes. In addition, ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2013 - Impact Journals LLC | Aging
A Moreno‐Ancillo, C Domínguez‐Noche, A.C. Gil-Adrados, Pedro M. Cosmes, Isabel Duarte, Yolanda Blanco Mateos,
Carboplatin (CP) hypersensitivity reactions have been reported in nearly 12 % of patients treated with this drug. The pathophysiologic mechanisms of these reactions have not been entirely elucidated. Various hypotheses are under discussion. CP hypersensitivity reactions could be IgE-mediated, caused by low-molecular platinum compounds acting as haptens. Platinum salts are also able to release histamine from basophils and mast cells, and some events seem to be non-immune-mediated direct histamine release. ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2003 - Elsevier BV | Allergologia et Immunopathologia
MJ García‐F‐Villalta, Magdalena Adrados, E. Daudén, J. Fraga, Ana Isabel García-Diez,
Journal of the European Academy of Dermatology and VenereologyVolume 18, Issue 2 p. 223-224 Pigmented metastasis of breast carcinoma mimicking malignant melanoma MJ García-F-Villalta, Corresponding Author MJ García-F-Villalta Departments of Dermatology and*Corresponding author, tel. +34 91 5202433; fax +34 91 5202435Search for more papers by this authorM Adrados, M Adrados Pathology, Hospital Universitario de la Princesa, C/Diego de León n°62, Madrid 28006, Spain.Search for more papers by this authorE ...
Tópico(s): Nonmelanoma Skin Cancer Studies
2004 - Wiley | Journal of the European Academy of Dermatology and Venereology
Juan Manuel Campos Adrados, Marly de Paulo Madruga,
Tópico(s): Spanish Literature and Culture Studies
2006 - | Boletim Academia Paulista de Psicologia
Isabel López, Beatriz Agúndez Reigosa, Sandra Adrados García, Enrique Villalobos Pinto, Julia Cano Fernández, Rodrigo Jiménez‐García,
Aim Procedures normally performed in the hospital setting are increasingly delivered as part of hospital at home (HAH) programmes. The aim of this study is to describe the procedures and diseases treated during the first 2 years of a new paediatric HAH programme. Methods This is a retrospective, observational study conducted in the HAH programme of Niño Jesús Children's Hospital (Spain). We included demographic data, diagnosis and procedures delivered to patients admitted to the HAH programme from ...
Tópico(s): Emergency and Acute Care Studies
2021 - Wiley | Journal of Paediatrics and Child Health
Cristina Prades, Isabel Gómez-Sánchez, Juan García‐Olmo, José Ramón González-Adrados,
Abstract The objective of this study was to assess the potential of visible and near infrared spectroscopy (VIS+NIRS) combined with multivariate analysis for identifying the geographical origin of cork. The study was carried out on cork planks and natural cork stoppers from the most representative cork-producing areas in the world. Two training sets of international and national cork planks were studied. The first set comprised a total of 479 samples from Morocco, Portugal, and Spain, while the second ...
Tópico(s): Plant Pathogens and Fungal Diseases
2011 - Taylor & Francis | Journal of Wood Chemistry and Technology
F Martínez-Orozco, José L. Vicário, Isabel Villalibre‐Valderrey, Clara de Andrés, Miguel Fernández‐Arquero, Rosa Peraita‐Adrados,
Summary Evidence suggests that autoimmune diseases tend to co‐occur so that patients with an autoimmune disorder are at higher risk of a second autoimmune disease. The association between allergic and autoimmune diseases is also of considerable interest. There are no reports on the association between sporadic or familial narcolepsy with cataplexy and other non‐neurological immune‐mediated diseases. This study reported on the comorbid immunopathological diseases associated with narcolepsy. One‐hundred ...
Tópico(s): Regulation of Appetite and Obesity
2014 - Wiley | Journal of Sleep Research
Camino Menéndez, Isabel Adrados, Asunción Fernández‐Barral, Benilde Jiménez, Juana M Flores, Marta Cañamero, Ernst‐Martin Füchtbauer, Friedrich Beermann, Ignacio Palmero,
Figure S1. Normal skin of TyrNRas/Ing1−/− mice, and melanoma incidence and percentage of lung or lymph node metastasis in TyrNRas/Ink4a/Arf−/− mice. Figure S2. Macroscopic appearance of melanocytic lesions in Ing1−/− mice and TRP2 immunohistochemistry of locally invasive TyrNRas/Ing1−/− lesions. TRP2 and Ki-67 staining of representative TyrNRas/wt and TyrNRas/Ing1+/− melanomas. Figure S3. Specificity of p19Arf IHC in melanin-rich melanomas. Figure S4. Western blot of p19Arf and p53 in melanomas ...
Tópico(s): Cell Adhesion Molecules Research
2014 - Wiley | Pigment Cell & Melanoma Research
Cristina Prades, Isabel Gómez-Sánchez, Juan García‐Olmo, Florentino González-Hernández, José Ramón González-Adrados,
Tópico(s): Postharvest Quality and Shelf Life Management
2014 - Springer Science+Business Media | Wood Science and Technology
Hui Ye, Chaobo Chen, Hanghang Wu, Kang Zheng, Beatriz Martín-Adrados, Esther Caparrós, Rubén Francés, Leonard J. Nelson, Manuel Gómez del Moral, Iris Asensio, Javier Vaquero, Rafael Bañares, Matías A. Ávila, Raúl J. Andrade, M. Isabel Lucena, María Luz Martínez‐Chantar, Helen L. Reeves, Steven Masson, Richard S. Blumberg, Jordi Gracia‐Sancho, Yulia A. Nevzorova, Eduardo Martı́nez-Naves, Francisco Javier Cubero,
Abstract Acetaminophen (APAP) hepatotoxicity induces endoplasmic reticulum (ER) stress which triggers the unfolded protein response (UPR) in hepatocytes. However, the mechanisms underlying ER stress remain poorly understood, thus reducing the options for exploring new pharmacological therapies for patients with hyperacute liver injury. Eight-to-twelve-week-old C57BL/6J Xbp1 -floxed ( Xbp1 f/f ) and hepatocyte - specific knockout Xbp1 mice ( Xbp1 ∆hepa ) were challenged with either high dose APAP [500 mg/kg] and ...
Tópico(s): Liver Disease Diagnosis and Treatment
2022 - Springer Nature | Cell Death and Disease
Maria Rosa Rifà Ros, Lluís Costa Tutusaus, Cristina Olivé Adrados, Àngela Pallarès Martí, Isabel Pérez Pérez, Carmen Vila Gimeno,
T he present research study tries to apply the nursing methodology of NANDA, NOC and NIC taxonomy to an immigrant population and presents the following Aims-To identify the most prevalent NANDA diagnoses linked to the migratory process of immigrant population and their families.-To elaborate and implement nursing care schemes adequate to the immigrant population and their families, using NANDA, NOC and NIC taxonomy.-To evaluate suitability and validity of the already made standard schemes. MethodologyThe ...
Tópico(s): Healthcare Systems and Practices
2006 - University of Alicante | Cultura de los Cuidados
Jacobo Rogado, Nuria Romero-Laorden, J.M. Sánchez-Torres, Ana M. Ramos‐Leví, Vilma Pacheco-Barcía, Ana Isabel Ballesteros, Reyes Arranz, Alicia Lorenzo, Pedro Gullón, Ana Garrido, José M. Serra López-Matencio, O. Donnay, Magdalena Adrados, Pablo Costas, Javier Aspa, Arántzazu Alfranca, Rebeca Mondéjar, Rámón Colomer,
Immunotherapy is an effective treatment in advanced cancer, although predictors of response are limited. We studied whether excess weight influences the efficacy outcomes of immunotherapy. We have also evaluated the combined prognostic effect of excess weight and immune-related adverse events (irAEs).Efficacy of anti-PD-1 treatment was evaluated with both objective radiological response (ORR) rate and progression-free survival (PFS), and toxicity with irAEs. We studied the association between excess ...
Tópico(s): Esophageal Cancer Research and Treatment
2020 - Landes Bioscience | OncoImmunology
O Teste de Raven e a Tecnica de Rorschach aplicados em populacao de 700 criancas, houve elevado indice de coerencia entre certas variaveis de Rorschach e as Matrizes Progressivas. Examinados os casos extremos classificados pelo Raven abaixo do percentil 5, constata-se serem eles, na sua maioria, portadores de serios problemas emocionais, embora normais sob o ponto de vista intelectual.
Tópico(s): Psychology and Mental Health
1979 - UNIVERSIDADE FEDERAL DO RIO DE JANEIRO | Arquivos brasileiros de psicologia
la autora procura explicar la organizacion y el desarrollo de la personalidad mediante el Metodo de Rorschach. Sistematiza los datos encontrados en grupos humanos con edades comprendidas entre 7 y 18 anos, considera tres variables como directamente relacionadas con el ego y su dinamica. Mediante su estudio, en las sucesivas fajas etarias, acompana el desarrollo de la personalidad. Todavia, encuentra igualmente importante para la correcta estructuracion de la personalidad la forma como fueron incorporadas ...
Tópico(s): Psychological Testing and Assessment
1981 - UNIVERSIDADE FEDERAL DO RIO DE JANEIRO | Arquivos brasileiros de psicologia
Isabel Adrados, Lucia García-López, Mario Aguilar‐Aragon, Eva Maranillo, María Domínguez,
Childhood cancer is a major cause of death in developed countries, and while treatments and survival rates have improved, long-term side effects remain a challenge. The genetic component of pediatric tumors and their aggressive progression, makes the study of childhood cancer a complex area of research. Here, we introduce the fruit fly Drosophila melanogaster as study model. We emphasize its numerous advantages, including binary gene expression systems that enable precise control over the timing ...
Tópico(s): Epigenetics and DNA Methylation
2024 - Elsevier BV | Methods in cell biology
J.L. Llisterri, R.M. Micó-Pérez, Sonsoles Velilla-Zancada, Gustavo C. Rodríguez-Roca, Miguel Ángel Prieto-Díaz, Vicente Martín, A. Barquilla García, José Polo García, Antonio Segura‐Fragoso, Sergio Cinza‐Sanjurjo, A. Barquilla García, Ángel Díaz Rodriguez, Carlos Escobar Cervantes, Francisco Javier Alonso Moreno, G.C. Rodríguez Roca, Jesús Vergara Martín, J.L. Llisterri, Juan J. Badimón, José Polo García, Luis Rodrı́guez Padial, Miguel A. Prieto, Rafael Vidal-Pérez, Sergio Cinza‐Sanjurjo, Sonia Miravet Jiménez, Sonsoles Velilla Zancada, Antonio López Téllez, Maria de Los Ángeles Ortega Osuna, Cristóbal Prieto Cid, María José Hidalgo Fajardo, José Lorente Serna, Ángel Requena, Ricardo Alberola Cañizares, Marcela Adasme Peña, Filomena Herrero Collado, Marcela Montes Vázquez, Rafael Ángel Carrascal Garrido, María Reyes Herrera Lozano, B. Oliva, Francisco José Anguita, Carmen Pérez Ibáñez, Carlos Alberto Cabrera Rodríguez, María José Rodriguez, Sandra Bonilla Ruiz, Rocío Reina González, Salomé Abad Sánchez, Inmaculada Santana Martínez, Rafael Sánchez Jordán, Juan María Ramos Navas-Parejo, José Manuel Ramírez Torres, José María Beltrán Poveda, M.A. de Cruz Benayas, Carmen Fernandez Gil, Jon Iñaki Esturo Alcaine, Antonio Mora Quintero, Fernando Leiva‐Cepas, José Luis Carrasco Martín, E. Criado, Mercedes Vázquez Blanco, Isabel Mora Ortiz, Leovigildo Ginel-Mendoza, Juan Carlos Aguirre Rodríguez, Esperanza Romero‐Rodríguez, José Acevedo Vázquez, Juan Gabriel García Ballesteros, María Lara, Patricia Agüera Moreno, Eduardo Paños Maturana, Juan Manuel Ignacio Expósito, Noelia Carrillo Peñas, Carmen María Abad Faya, Ana Marina Almagro Duque, Rubén Torrescusa Camisón, Paloma Menéndez Polo, Marina Peña García, Cristina López Fernández, Ascensión Estepa Torres, M.G.M.J. Jansen, Esperanza González, Lisardo García Matarin, Enrique Luna, Javier Benítez Rivero, María José Gómez González, Carmen Gómez Montes, Eva Calvo, Concepción Calvo, Susana Larripa de La Natividad, Germán Grasa Lambea, Emilio Marín, Ana Cristina Navarro Gonzalvo, Antonio Pablo Martínez Barseló, Irene León, E. Lidia Gutiérrez Fernández, Fernando Andrés Mantecón, Ana Belén García-Garrido, Asunción Velez Escalante, Luisa Alonso Rentería, Jesús Sainz Jiménez, Guillermo Pombo Alles, J.A. Divisón, Pedro Martínez Sotodosos, Juan Antonio Vivancos Fuster, María García Palencia, José Ambrosio Torres Moraleda, Sara González Ballesteros, A.C. Gil Adrados, Antonio González Cabrera, Miguel Ángel Babiano Fernández, Guillermo García-García, Juan José Criado‐Álvarez, Pilar Torres Moreno, Francisco Javier Arribas Aguirregaviria, Alicia Sahuquillo Martínez, Lourdes María Santos Béjar, Miguel Laborda Peralta, Raúl Piedra Castro, C. Santos Altozano, Lucía González-Tarrio Polo, Pedro Valiente Maresca, Reinilda Mota Santana, Noemí Elizabeth Terrero Ledesma, Noelia Garrido Espada, Francisco Javier Alonso Moreno, G Calvi, Juan Lorenzo Gutiérrez Montero, Juan Ignacio López Gil, María Dolores Fernández Ortega, Miren Elizari Roncal, María Ascensión López Serrano, Nuria Esther Adrián de La Fuente, Belén Angulo Fdez. de Larrea, Naiara Cubelos Fernández, Guiomar Luz Ferreiro Gómez, Diana Gómez Rodríguez, Sonia María Andrés Tuñón, María Ajenjo González, Serafín de Abajo Olea, Juan José León Regueras, César Manuel Gallego Nieto, Delio Vázquez Mallada, Maria de La O Gutiérrez García, Pablo Rodriguez, José Ignacio Ferradal García, Blanca Delia de Román Martínez, ana Arconada Pérez, Omar Mahmoud Atoui, Álvaro Morán Bayón, María Teresa Armenteros del Olmo, F.J. García-Norro Herreros, Enrique Méndez Rodríguez, Diana María Narganes Pineda, Verónica Ortiz Ainaga, Milagros Sonlei Sánchez Guevara, Laura Villota Ferreiro, M. Teresa Grande Grande, Francisco Vicente Martínez Gracía, María Dolores Moriano García, Beatriz Muñoz, Gemma Rovira Marcelino, Diana Elizabeth Fernández Valverde, Roser Rodó Bernadó, María Teresa Ortiz Lupiáñez, Najlaa Najih, José María Diéguez Parra, María Rosa Benedicto Acebo, Mari Luz Bravo Vicien, Alberto Ramón León Estella, Juan Gomez, Alicia Mostazo Muntané, Isabel Ortega Abarca, Anna Gasol Fargas, B.E. Riesgo Escudero, Susana Elizabeth Riesgo, Edgar Zaballos Castellvi, Celia Cols Sagarra, Marta Herranz Fernández, Josep Alins Presas, Idaira Damas Pérez, Rosa Garcia, Inés Monte Collado, Roberto Genique Martínez, María José Guasch Villanueva, Teresa Martínez, Lucio Pinto Pena, Josefa María Panisello Royo, Inés Gil Gil, Alberto Calderón Montero, María del Mar Zamora Gómez, E Cebrián, María José Piñero Acin, Celia Pecharromán Sacristán, Mercedes Vicente, María Paz Pérez Unanua, Nuria Marañón Henrich, Saray Gómez Monreal, S. Redondo de Pedro, B. Sanz Pozo, Irene Moreno Martínez, B. López Uriarte, Carmelina Sanz Velasco, Amaya Gárriz Aguirre, Montserrat Rivera Teijido, G. Reviriego Jaén, José Ignacio Aza Pascual-Salcedo, Josefa Vázquez Gallego, Julia Caballer Rodilla, Aida Marisa Magalhães Herrera, Ezequiel Arranz Martínez, Ana María Calvo, Paula Morán Oliva, María Milagros González Béjar, Julio Antonio Heras Hitos, O. García Vallejo, Manuel de Jesús Frías Vargas, María Jesús Castillejo Boguerin, A. García Lerín, Miguel Ángel María Tablado, Guillermo García-García, Leticia de Miguel Acero, Carmen Zárate Oñate, Aránzazu Barranco Apoita, M. Belloso, Ana María Huertas Velasco, Rafael Sáez Jiménez, Julia Natividad García Pascual, M. Clemencia Zuluaga, M. Cruz Díez Pérez, Antonio Ruiz García, Cristina Murillo Jelsbak, Virginia Lasso Oria, Amelia González Gamarra, Vicente Pascual Fuster, María Dolores Aicart Bort, Natividad Vázquez Gómez, Carlos Lluna Gasco, Teresa Amoros Barber, P. Cano, Miguel Monteagudo Moncho, María Jesús Larré Muñoz, Raquel Navarro Hernández, Francisco José Martínez Egea, Antonio Tramontano, M. Ferrer Royo, Belén Persiva Saura, Juan Andrés Torres, José María Moliner, Alejandro Salanova Penalba, Ariadna Cucó Alberola, F.M. Navarro Ros, Enrique Beltrán Llicer, Ana Novas, Inmaculada Martín Valls, Gracia Verdú Mahiques, Enrique Peña Forcada, Nieves Aguilar Gómez, Francisco Javier Sanz García, Miriam Bueso, María Eugenia Romero, Antonio Francés Camus, María Amparo Antón Peinado, Rosa Latorre Santos, María Asunción Palomar Marín, María Carmen Botella García, Eva Sánchez Fresquet, Pedro Sala Paños, T. Sánchez Ruíz, Rosa Ana Valero Valero, María Seoane Vicente, Magdalena Martín Llinares, Antonio Masiá Alegre, J.L. Llisterri, Irene Lluch Verdú, Vicente Pallarés‐Carratalá, Francisco Valls Roca, R.M. Micó Pérez, Jacinto Espinosa García, José Ignacio Prieto Romo, Leandro Fernández‐Pérez, Javier Sierratapia, Nieves Moreno Regidor, Francisco Javier Zaballos Sánchez, Ana Moreno Moreno, Francisco Barrera, Juan José Vázquez, María José Gamero Samino, Miguel Ángel de Santiago Rodríguez, Pablo Rafael Gómez Martínez, Antonio Carlos Elías Becerra, Javier Soto Olivera, Víctor Cambero, Julián Domínguez Ávila, Andrés Simón Fuentes, J.M. Jiménez, Dimas Igual Fraile, G. Nieto Barco, I. Ramos, María Luz Serrano Berrocal,
To determine the prevalence of chronic kidney disease (CKD) and the factors associated with impaired renal function in the population attended in primary care (PC).Cross-sectional and multicentre study carried out in the baseline patients of the IBERICAN study (Identificación de la poBlación Española de RIesgo CArdiovascular y reNal). CKD was considered with an estimated glomerular filtration (eGF) <60ml/min/1.73 m2 or elevated albuminuria (≥ 30mg/g). According to the eGF, the CKD was classified in six ...
Elsevier BV
Marta Carretero, M.J. Escámez, Marta García, Isabel Mirones, Blanca Duarte, Almudena Holguín, Fernando Asensio, Rosa Peraita‐Adrados, José L. Jorcano, Marcela Del Río, Fernando Larcher,
Antimicrobial peptides are major components of the innate defense system that present microbicidal activity against gram positive and negative bacteria, yeast, and some enveloped viruses. The human cathelicidin LL-37 is expressed in skin upon wounding and, in addition to its role in antimicrobial defense, it has also been previously demonstrated that this peptide might be involved in reepithelization. We have generated an adenoviral vector containing the complete sequence of LL-37 along with an ...
Tópico(s): RNA Interference and Gene Delivery
2008 - Wiley | Wound Repair and Regeneration
Isabel Cano, María D. Lozano, Álvaro Rodríguez, Alberto Mate, Magdalena Adrados, María Del Mar López, Ruben Carro, Santiago Montes‐Moreno,
HistopathologyVolume 57, Issue 1 p. 159-162 Correspondence Nodular lymphocyte-predominant Hodgkin lymphoma and T cell histiocyte-rich large B cell lymphoma: diagnosis in two monozygotic twins Isabel Cano, Isabel Cano Department of Hematology, Mancha-Centro Hospital, Ciudad RealSearch for more papers by this authorMaría Lozano, María Lozano Lymphoma Group, Molecular Pathology Programme, Spanish National Cancer Centre, MadridSearch for more papers by this authorÁlvaro Rodríguez, Álvaro Rodríguez Department ...
Tópico(s): CNS Lymphoma Diagnosis and Treatment
2010 - Wiley | Histopathology
... alphabet - CRISTINA MARIA NEGRÃO ABRANCHES GUERREIRO FRANCISCO R. ADRADOS, Historia de la Lengua Griega. De los orígenes a nuestros días - CUSTÓDIO MAGUEIJO FRANCISCO R. ADRADOS, La Dialectología griega cono fuente para el estudio ... migraciones indoeuropeas en Grecia - CUSTÓDIO MAGUEIJO FRANCISCO R. ADRADOS, La Dialectología Griega, hoy (1952-1995) - CUSTÓDIO MAGUEIJOFELIX ...
Tópico(s): Medieval Iberian Studies
2000 - University of Lisbon | Euphrosyne
... Nos referimos a la traducción de Francisco Rodríguez Adrados, que comenzó a publicarse por la Editorial Hernando ... Mendoza’, en ‘Curiositas nihil recusat’. Estudios dedicados a Isabel Moreno Ferrero, ed. Juan Antonio González Iglesias, Julián ... Cátedra García, María Luisa López-Vidriero Abello & María Isabel de Páiz Hernández, 2 vols (Salamanca: IHLL, 2005), ...
Tópico(s): Historical, Religious, and Philosophical Studies
2023 - Routledge | Bulletin of Spanish Studies
... Reception of Epic - R. M. ROSADO FERNANDESFRANCISCO R. ADRADOS, Del teatro griego al teatro de hoy - AIRES ...
Tópico(s): Medieval Iberian Studies
2005 - University of Lisbon | Euphrosyne