From Peter Hazelhurst, By Michael Horsnell, , John Witherow, Richard Ford, By Clifford Webb Midlands Industrial Correspondent, By Frances Gibb, By George Clark Political Correspondent, From Robert Fisk, From Paul Routledge Labour Editor, By Fred Emery Political Editor, By a Staff Reporter, By Michael Baily Transport Correspondent, From Annabel Ferriman Health Services Correspondent, By Ian Bradley, By Edward Townsend, By Our Political Editor, From Our Correspondent, By John Roper, From Christopher Warman, By Hugh Clayton Agriculture Correspondent, By Nicholas Timmins, From Arthur Osman, By Henry Stanhope Defence Correspondent, By John Young Planning Reporter, From Our Education Correspondent, By Kenneth Gosling Arts Reporter, By Harry Golombek Chess Correspondent, By Pat Healy Social Services Correspondent, By Diana Geddes Education Correspondent, By Lucy Hodges, By Arthur Reed Air Correspondent, By Stanley Baldwin, From Patricia Clough, From David Wood, From Charles Hargrove, From Robert Schuil, From Patrick Brogan, By Hugh Noyes Parliamentary Correspondent, From Patrick Knight, by Arrigo Levi, From Christopher Walker, From Tewfik Mishlawi, From Michael Leapman, From Ivor Davis, From Hasan Akhtar, From Denis Reinhardt, Dessa Trevisan, From Richard Hughes, Michael Ratcliffe, Jacky Gillott, H. R. F. Keating, Michael Church, Ned Chaillet, Brian Martin, Nikolai Tolstoy, John Hackett, Jenny Woolf, Shona Crawford Poole, Hugh Clayton, John Higgins, John Percival, Joan Bakewell, Stanley Sadie, Barry Millington, Ronald Butt, Bernard Levin, Alan Hamilton, CARLOS BRAGA, , JOAOUIM JOSE, , BARBOSA ROMERO, , JULIO BARREIROS, MARTINS, , JOSE MANUEL VAZ, , CARLOS AUGUSTO, , G. MOURA BRANCO, , HERNANI LOPES, , da SILVA MALA, , L. CHAINHO, , PEREIRA, , L. de JESUS, SANTOS SOARES, , S. SANTOS, , JOAO PINHEIRO, , C. A. A. BERNARDO, , JOAO FERREIRA, , MARIA ISABEL, CALADO FERREIRA, , VIRGINIA M. GERGORIO, , EDITE M. G. P. FERNANDES, , JOSE MANUEL E. VALENCA, , MARIA RAQUEL VALENCA, , RAUL VIDAL, MARIO de ARAUJO, , REX DAVIS, , T. A. BIRRELL, , HUGH PESKETT, , W. E. BAUGH, , IAIN MONCREIFFE OF THAT ILK, , W. H. HANKIN, , ANTONY WHITAKER, , A. L. S. CORNER, , RICHARD RITGHIE, , TITO BENADY, , KENNET, , NOEL ANNAN, , MICHAEL HOLROYD, , DAVID GARNETT, , VICTOR PRITCHETT, , EVAN LUARD, , D. R. MIDGLEY, , ADRIAN C. BOULT, , GERTRUDE M. BANNISTER, , By the Staff of Nature, From Our Own Correspondent, By Geraldine Norman Sale Room Correspondent, By Clifford Longley Religious Affairs Correspondent, Cyril Bainbridge, By our Arts Reporter, W. W. W. and J. B. write:, Baroness Airey of Abingdon writes:, By Mitchell Platts, By Keith Macklin, By John Nicholls, John Young, From Richard Streeton, By John Woodcock Cricket Correspondent, By Michael Seely, By Norman Fox Football Correspondent, By Our Rifle Shooting Correspondent, By Pamela Macgregor-Morris, By John Watson, By Peter Hill Industrial Editor, By David Felton Labour Reporter, By Roman Eisenstein Banking Correspondent, By John Whitmore Financial Correspondent, By Tim Jones, From Michael Hornsby, By Peter Wilson-Smith, From Frank Vogl, William Olsen, By Kenneth Owen Technology Editor, By Bill Johnstone, By Margaret Stone, By Nicholas Hirst Energy Correspondent, MELVILLE BERNSTEIN, , MRS M. D. LOVEDAY, , JOHN GADD, , A. C. PARSONS, , J. B. DANEL, , HUGH CAWDRON, , BY THE FINANCIAL EDITOR, Ross Davies, David Blake, Derek Harris, Michael Prest Mining correspondent, By Our Financial Staff, By Rosemary Unsworth, Peter Davalle,
News: EEC budget is approved seven months late, Latest pamphlets Religious beliefs of Elgar, The Times Cook Separate ways with eggs, Kidnap victim is ...
1980 - Gale Group | TDA
Ana C. Magalhães, Ana Ferreira, Sílvia Gomes, Marta Vieira, Ana Gouveia, Isabel Valença, Markus Islinger, Rute Nascimento, Michael Schrader, Jonathan C. Kagan, Daniela Ribeiro,
Abstract The human cytomegalovirus developed distinct evasion mechanisms from the cellular antiviral response involving vMIA, a virally-encoded protein that is not only able to prevent cellular apoptosis but also to inhibit signalling downstream from mitochondrial MAVS. vMIA has been shown to localize at mitochondria and to trigger their fragmentation, a phenomenon proven to be essential for the signalling inhibition. Here, we demonstrate that vMIA is also localized at peroxisomes, induces their ...
Tópico(s): RNA regulation and disease
2016 - Nature Portfolio | Scientific Reports
Isabel Valença, Nelma Pértega‐Gomes, José R. Vizcaíno, Rui Henrique, Carlos Lopes, Fátima Baltazar, Daniela Ribeiro,
Abstract Previous studies on monocarboxylate transporters expression in prostate cancer ( PCa ) have shown that monocarboxylate transporter 2 ( MCT 2) was clearly overexpressed in prostate malignant glands, pointing it out as a putative biomarker for PCa . However, its localization and possible role in PCa cells remained unclear. In this study, we demonstrate that MCT 2 localizes mainly at peroxisomes in PCa cells and is able to take advantage of the peroxisomal transport machinery by interacting with Pex19. ...
Tópico(s): Cancer, Lipids, and Metabolism
2015 - Wiley | Journal of Cellular and Molecular Medicine
Produção Nacional
Revisado por pares
Céline Pinheiro, Valter Penna, Filipa Morais-Santos, Lucas Faria Abrahão‐Machado, Guilherme Ribeiro, Emílio Martins Curcelli, Marcus V. Olivieri, Sandra Morini, Isabel Valença, Daniela Ribeiro, Fernando Schmitt, Rui Manuel Reis, Fátima Baltazar,
Soft tissue sarcomas (STSs) are a group of neoplasms, which, despite current therapeutic advances, still confer a poor outcome to half of the patients. As other solid tumors, STSs exhibit high glucose consumption rates, associated with worse prognosis and therapeutic response. As highly glycolytic tumors, we hypothesized that sarcomas should present an increased expression of lactate transporters (MCTs). Immunohistochemical expression of MCT1, MCT2, MCT4 and CD147 was assessed in a series of 86 STSs ...
Tópico(s): Cardiac tumors and thrombi
2014 - BioMed Central | Journal of Translational Medicine
Isabel Valença, Filipa Morais-Santos, Vera Miranda‐Gonçalves, Ana Ferreira, Cristina Almeida Aguiar, Fátima Baltazar,
Abstract Background Propolis is a resin collected by bees from plant buds and exudates, which is further processed through the activity of bee enzymes. Propolis has been shown to possess many biological and pharmacological properties, such as antimicrobial, antioxidant, immunostimulant and antitumor activities. Due to this bioactivity profile, this resin can become an alternative, economic and safe source of natural bioactive compounds. Antitumor action has been reported in vitro and in vivo for ...
Tópico(s): Phytochemistry Medicinal Plant Applications
2013 - BioMed Central | BMC Complementary and Alternative Medicine
Jodi L. Pawluski, Andreia Valença, Ana Isabel Santos, João Costa-Nunes, H.W.M. Steinbusch, Tatyana Strekalova,
Abstract Pregnancy is a time of distinct neural, physiological and behavioral plasticity in the female. It is also a time when a growing number of women are vulnerable to stress and experience stress-related diseases, such as depression and anxiety. However, the impact of stress during gestation on the neurobiology of the mother has yet to be determined, particularly with regard to changes in the hippocampus; a brain area that plays an important role in stress-related diseases. Therefore, the aim of the ...
Tópico(s): Maternal Mental Health During Pregnancy and Postpartum
2012 - Elsevier BV | Neuroscience
Isabel Valença, Ana Ferreira, Marcelo Correia, Sandra Kühl, Carlo van Roermund, Hans R. Waterham, Valdemar Máximo, Markus Islinger, Daniela Ribeiro,
Reprogramming of lipid metabolism directly contributes to malignant transformation and progression. The increased uptake of circulating lipids, the transfer of fatty acids from stromal adipocytes to cancer cells, the de novo fatty acid synthesis, and the fatty acid oxidation support the central role of lipids in many cancers, including prostate cancer (PCa). Fatty acid β-oxidation is the dominant bioenergetic pathway in PCa and recent evidence suggests that PCa takes advantage of the peroxisome transport ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2020 - Multidisciplinary Digital Publishing Institute | Cancers
Ana Ferreira, Ana Gouveia, Ana C. Magalhães, Isabel Valença, Mariana Marques, Jonathan C. Kagan, Daniela Ribeiro,
Upon intracellular recognition of viral RNA, RIG-I-like proteins interact with MAVS at peroxisomes and mitochondria, inducing its oligomerization and the downstream production of direct antiviral effectors. The human cytomegalovirus (HCMV) is able to specifically evade this antiviral response, via its antiapoptotic protein vMIA. Besides suppressing the programmed cell death of infected cells, vMIA inhibits the antiviral signalling at mitochondria by inducing the organelle's fragmentation, consequently ...
Tópico(s): RNA regulation and disease
2022 - Frontiers Media | Frontiers in Cell and Developmental Biology
Produção Nacional
Cecília Nogueira Valença, Isabel Cristina Araújo Brandão, Raimunda Medeiros Germano, Rosana Lúcia Alves de Vilar, Akemi Iwata Monteiro,
O uso indiscriminado de drogas entre os jovens cresce progressivamente no Brasil e no mundo. Este estudo objetivou refletir acerca da abordagem ética da enfermagem na atenção a adolescentes usuários de drogas lícitas e ilícitas. Trata-se de um estudo teórico de caráter reflexivo fundamentado em uma revisão bibliográfica do tipo narrativa, utilizando livros e artigos científicos. Emergiram reflexões sobre a dependência de substâncias psicoativas em expansão na adolescência que culminaram na discussão ...
Tópico(s): Health, Nursing, Elderly Care
2013 - UNIVERSIDADE FEDERAL DO RIO DE JANEIRO | Escola Anna Nery
Sebastian Gulde, Tobias Wiedemann, Mathias Schillmaier, Isabel Valença, Amelie Lupp, Katja Steiger, Hsi-Yu Yen, Stephen Bäuerle, Johannes Notni, Raúl M. Luque, Herbert Schmid, Stefan Schulz, Donna P. Ankerst, Franz Schilling, Natalia S. Pellegata,
Invasive nonfunctioning pituitary tumors (NFPTs) are non-resectable neoplasms associated with frequent relapse and significant comorbidities. Current treatments, including somatostatin receptor 2 (SSTR2)-directed somatostatin analogs (SSAs), often fail against NFPTs. Thus, identifying effective therapies is clinically relevant. As NFPTs express SSTR3 at high levels, pasireotide, a multireceptor-targeted SSA, might be beneficial. Here we evaluated pasireotide in the only representative model of spontaneous ...
Tópico(s): Growth Hormone and Insulin-like Growth Factors
2021 - Multidisciplinary Digital Publishing Institute | Cancers
Diana Julião, Ana C. Gomes, Martyn Pillinger, André D. Lopes, Rita Valença, Jorge C. Ribeiro, Isabel S. Gonçalves, Salete S. Balula,
Oxidative desulfurization (ODS) is a method of removing sulfur from diesel fuel that has the potential to complement or even replace conventional hydrodesulfurization processes in oil refineries. One of the most promising variants of ODS is extractive and catalytic ODS (ECODS) in which the organic sulfur compounds in the liquid fuel are oxidized and extracted in situ from the oil phase into an extractant phase. In this study, the desulfurization of model and real diesel fuel has been performed in ...
Tópico(s): Nanomaterials for catalytic reactions
2020 - Elsevier BV | Journal of Molecular Liquids
Diana Julião, Ana C. Gomes, Martyn Pillinger, Rita Valença, Jorge C. Ribeiro, Isabel S. Gonçalves, Salete S. Balula,
Efficient and recyclable liquid–liquid extraction and catalytic oxidative desulfurization (ECODS) systems for the removal of refractory sulfur compounds from liquid fuels are reported that use the cyclopentadienyl molybdenum tricarbonyl complexes [CpMo(CO)3Me] (1), [CpMo(CO)3(CH2-pC6H4-CO2Me] (2) and [CpMo(CO)3CH2COOH] (3) as catalyst precursors. An ionic liquid, 1-butyl-3-methylimidazolium hexafluorophosphate, was used as both extractant and reaction medium, entrapping the active homogeneous MoVI catalysts ...
Tópico(s): Catalysis for Biomass Conversion
2018 - Elsevier BV | Applied Catalysis B Environment and Energy
Carlos M. Granadeiro, P. Ferreira, Diana Julião, L. Ribeiro, Rita Valença, Jorge C. Ribeiro, Isabel S. Gonçalves, Baltazar de Castro, Martyn Pillinger, Luís Cunha‐Silva, Salete S. Balula,
This work proposes an efficient desulfurization system to produce low sulfur diesel under sustainable and moderate experimental conditions. Treatment of a real diesel with a sulfur content of 2300 ppm led to 80% desulfurization after 2 h. The processes used conciliate liquid-liquid extraction and sulfur oxidative catalysis. The catalytic performance of the commercial Keggin-polyoxomolybdate H3[PMo12O40] (PMo12) was strategically increased by simple cation exchange, using a long carbon chain (ODAPMo12, ...
Tópico(s): Metal-Organic Frameworks: Synthesis and Applications
2018 - Multidisciplinary Digital Publishing Institute | Energies
Diana Julião, Ana C. Gomes, Martyn Pillinger, Rita Valença, Jorge C. Ribeiro, Isabel S. Gonçalves, Salete S. Balula,
The oxidative desulfurization of model and real diesel has been studied using the complex [MoO2Cl2(4,4'-di-tert-butyl-2,2'-bipyridine)] as (pre)catalyst, aq. H2O2 as oxidant, and an ionic liquid as extraction solvent. Under moderate conditions (50 °C) and short reaction times (<3 h), dibenzothiophene, 4-methyldibenzothiophene and 4,6-dimethyldibenzothiophene could be completely removed from the model diesel. The (pre)catalyst 1 was transformed in situ to the active catalyst [MoO(O2)2(di-tBu-bipy)]. By sequentially ...
Tópico(s): Asymmetric Hydrogenation and Catalysis
2016 - Royal Society of Chemistry | Dalton Transactions
Diana Julião, Ana C. Gomes, Luís Cunha‐Silva, Martyn Pillinger, André D. Lopes, Rita Valença, Jorge C. Ribeiro, Isabel S. Gonçalves, Salete S. Balula,
The complexes [MoO2Cl2(DMB)2] (1) and [MoO2Cl2(DEO)] (2) (DMB = N,N-dimethylbenzamide, DEO = N,N′-diethyloxamide) have been evaluated as catalysts in extractive-catalytic oxidative desulfurization (ECOD) of a simulated diesel fuel. Using the ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM]PF6) as extraction solvent and H2O2 as oxidant, ultra-deep desulfurization (S-content from 3000 ppm to <10 ppm) was possible within a reaction time of 1–3 h, and the systems Catalyst/[BMIM]PF6 could be recycled ...
Tópico(s): Catalytic Processes in Materials Science
2019 - Elsevier BV | Catalysis Communications
Produção Nacional
Revisado por pares
Carlos C. Epitácio-Pereira, Gabriella M. F. Silva, Roberto Salvatori, João A. M. Santana, Francisco A. Pereira, Miburge B. Góis‐Júnior, Allan Valadão de Oliveira Britto, Carla R. P. Oliveira, Anita H. O. Souza, Elenilde G. Santos, Viviane C. Campos, Rossana M. C. Pereira, Eugênia H. O. Valença, Rita A. A. Barbosa, María Isabel Farías, Francisco José Albuquerque de Paula, Taisa V. Ribeiro, Mario C. P. Oliveira, Manuel H. Aguiar‐Oliveira,
The GH/IGF-I axis is important for bone growth, but its effects on joint function are not completely understood. Adult-onset GH-deficient individuals have often reduced bone mineral density (BMD). However, there are limited data on BMD in adult patients with untreated congenital isolated GH-deficient (IGHD). We have shown that adult IGHD individuals from the Itabaianinha, homozygous for the c.57+1G>A GHRHR mutation, have reduced bone stiffness, but BMD and joint status in this cohort are unknown.The ...
Tópico(s): Hip disorders and treatments
2013 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
Lígia Vieira Claudino, Ana Maria Gondim Valença, Maria Isabel Dantas de Medeiros, Luana Abílio Diniz Melquíades de Medeiros, Severino Jackson Guedes de Lima,
O presente trabalho objetivou avaliar a superficie do esmalte humano submetido a acao de diferentes sucos de frutas citricas, em microscopia eletronica de varredura (MEV). Foram selecionados 22 dentes extraidos por razoes ortodonticas, livres de trincas e/ou fraturas, sendo obtidos 44 blocos de esmalte a partir das superficies vestibulares e linguais/palatinas destes elementos. Os blocos foram aleatoriamente divididos em 10 grupos experimentais (n = 4), submetidos ao contato por 5 minutos com: sucos ...
Tópico(s): Meat and Animal Product Quality
2006 - Editora da Pontifícia Universidade Católica do Rio Grande do Sul (EDIPUCRS) | Revista Odonto Ciência
Diana Julião, Ana C. Gomes, Martyn Pillinger, Rita Valença, Jorge C. Ribeiro, Isabel S. Gonçalves, Salete S. Balula,
Regulations on the permissible levels of sulfur in transportation fuels are becoming ever more strict, with a global shift towards “zero sulfur” fuels, and the revamp of existing hydrodesulfurization (HDS) facilities to meet these lower caps is cost‐prohibitive. Metal‐catalyzed sulfoxidation chemistry is viewed as an economically viable desulfurization strategy that could complement conventional HDS technology. In the present work, the complex [ η 5 ‐IndMo(CO) 3 Me] ( 1 ) (Ind = indenyl) was employed in the ...
Tópico(s): Polyoxometalates: Synthesis and Applications
2020 - Wiley | Applied Organometallic Chemistry
Francisco dos Santos, Sandra Magalhães, Magda Carvalho Henriques, Beatriz Silva, Isabel Valença, Daniela Ribeiro, Margarida Fardilha, Alexandra Nunes,
Introduction: Prostate Cancer (PCa) is the second most common neoplasia in men. Because it is often diagnosed at a late stage, mortality rates remain high. Studying cancer metabolome, which reflects early changes that occur in cells, has gained relevance and may contribute to the identification of early diagnostic biomarkers and understanding tumor biology. Methods: Fourier-transform infrared (FTIR) spectroscopy is a metabolomics technique that probes the biochemical composition of the analyzed samples ...
Tópico(s): Spectroscopy and Chemometric Analyses
2018 - | Current Metabolomics
Diana Julião, Ana C. Gomes, Martyn Pillinger, Rita Valença, Jorge C. Ribeiro, Baltazar de Castro, Isabel S. Gonçalves, Luís Cunha‐Silva, Salete S. Balula,
The zinc‐substituted polyoxotungstate [PW 11 Zn(H 2 O)O 39 ] 5– (PW 11 Zn) has been encapsulated within the aluminium(III) 2‐aminoterephthalate NH 2 ‐MIL‐101(Al) metal–organic framework (MOF) either directly through a one‐pot microwave‐assisted synthesis or by an impregnation method. The resultant composite materials were characterized by elemental analysis, powder X‐ray diffraction, FTIR spectroscopy, and 31 P magic‐angle spinning (MAS) NMR spectroscopy. The desulfurization of a model diesel containing ...
Tópico(s): Catalysis and Hydrodesulfurization Studies
2016 - Wiley | European Journal of Inorganic Chemistry
A trajetória de Isabel Valença, popularizada no carnaval como “Chica da Silva” nos permite perceber a importância da relação estabelecida entre a cultura e a mídia, para o debate sobre gênero e raça nos anos 1960\70. Utilizando jornais, entrevistas com antigos sambistas e livros de jornalistas e pesquisadores desenvolvi as bases deste artigo. Representando uma escrava no período colonial, Isabel sintetizou a força de superação das mulheres, se tornando um exemplo a ser seguido. A imprensa ajudou a construir o ...
Tópico(s): Brazilian cultural history and politics
2013 - FUNDAÇÃO GETÚLIO VARGAS | Mosaico
Diana Julião, Ana C. Gomes, Luís Cunha‐Silva, Rita Valença, Jorge C. Ribeiro, Martyn Pillinger, Baltazar de Castro, Isabel S. Gonçalves, Salete S. Balula,
Highly efficient, deep desulfurization of a multi-component model diesel containing benzothiophene (BT), dibenzothiophene (DBT) and 4,6-dimethyldibenzothiophene (4,6-DMDBT) has been achieved by using the peroxophosphomolybdate [(n-C4H9)4N]3{PO4[MoO(O2)2]4} (Q3PMo4) directly as catalyst, and aqueous H2O2 as oxidant. Q3PMo4 behaves as a heterogeneous catalyst in the complete oxidation of the various sulfur compounds to the corresponding sulfones within 3 h at 70 °C, using a relatively low H2O2/S molar ratio ...
Tópico(s): Asymmetric Hydrogenation and Catalysis
2019 - Elsevier BV | Applied Catalysis A General
Diana Julião, Fátima Mirante, Susana O. Ribeiro, Ana C. Gomes, Rita Valença, Jorge C. Ribeiro, Martyn Pillinger, Baltazar de Castro, Isabel S. Gonçalves, Salete S. Balula,
A combination of catalytic oxidation and extraction was used for the desulfurization of a model diesel containing benzothiophene, dibenzothiophene and 4,6-dimethyldibenzothiophene, or a real diesel sample with a sulfur content of 2300 ppm. The catalysts used were the soluble peroxo compound (nBu4N)3{PO4[WO(O2)2]4} (PW4) and a supported material denoted as PW4@TMA-SBA-15 that was prepared by immobilization of PW4 in an ordered mesoporous silica (SBA-15) derivatized with propyltrimethylammonium groups ( ...
Tópico(s): Chemical Synthesis and Reactions
2018 - Elsevier BV | Fuel
Produção Nacional
Revisado por pares
Isabel Boaventura Monteiro, David Valença Dantas, Maristela Cavicchioli Makrakis, Luciano Lorenzi, Sofia Alves Ribeiro, Ana Paula Testa Pezzin, Victória Fonseca Silveira, Eduardo Gentil,
With the objective of characterizing the composition and spatial distribution of plastic fragments in a subtropical lagoon system, five sample areas affected by various anthropogenic impacts were chosen in the southern part of the Estuarine Lagoon System in Laguna, Santa Catarina, Brazil. The total density of the floating meso- and microplastics encountered was 7.32/m3, with the greatest density in the access channel and external area of the lagoon. Plastic filament was the most abundant and mainly ...
Tópico(s): biodegradable polymer synthesis and properties
2022 - Elsevier BV | Marine Pollution Bulletin
Produção Nacional
Cecília Nogueira Valença, Isabel Cristina Araújo Brandão, Raimunda Medeiros Germano, Rosana Lúcia Alves de Vilar, Akemi Iwata Monteiro,
The indiscriminate use of drugs by the youth is growing steadily in Brazil and worldwide. This study was aimed at reflecting about the professional nursing practice's ethical approach in providing care to adolescents who are users of legal and illegal drugs. This is a theoretical and reflective study based on narrative literature review, using books and scientific articles. Reflections about addiction to psychoactive substances in expansion among adolescents have emerged, and resulted in the discussion ...
Tópico(s): Contemporary Social and Educational Issues
2013 - UNIVERSIDADE FEDERAL DO RIO DE JANEIRO | Escola Anna Nery
Produção Nacional
Revisado por pares
Tópico(s): Rural and Ethnic Education
2020 - | Revista Canoa do Tempo
Produção Nacional
Revisado por pares
Mónica Santos, Maria do Carmo Costa, Maria Edite Rio, María José Sá, Marta Chagas Monteiro, Angela Valença, Alfredo Sá, José Dinis, José Figueiredo, L Bigotte de Almeida, António Valongueiro, Isabel Coelho, Teresa Matamá, Jorge Pinto‐Basto, Jorge Sequeiros, Patrı́cia Maciel,
Multiple sclerosis (MS) is a demyelinating disease that affects about one in 500 young Europeans. In order to test the previously proposed influence of the A PO E and SC A 2 loci on susceptibility to MS, we studied these loci in 243 Portuguese patients and 192 healthy controls and both parents of 92 patients. We did not detect any significant difference when A PO E and SC A 2 allele frequencies of cases and controls were compared, or when we compared cases with different forms of the disease. Disequilibrium ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2004 - SAGE Publishing | Multiple Sclerosis Journal
Produção Nacional
Revisado por pares
Ana Lúcia Paz Cardozo, Eduardo Gentil, Jorge Luiz Rodrigues Filho, Isabel B. Moteiro, Tatianny M. Scandolo, David Valença Dantas,
Atlantic Bigeye (Priacanthus arenatus) is a demersal species from the Priacanthidae family with little literature relating to its biology and catch aspects. Due to this lack of research, the focus of this effort was to describe the feeding preferences of Atlantic Bigeye and to evaluate the influence of plastic debris derived from the local fisheries activities on its diet. The most important items were Corophiidae, Penaeidae, Actinopterygii, Isopoda, Cephalopoda, Policheta and plastic. Plastic was ...
Tópico(s): Recycling and Waste Management Techniques
2018 - Elsevier BV | Marine Pollution Bulletin
Produção Nacional
Revisado por pares
Cleyson Valença Reis, Sonia Aparecida de Andrade, Oscar Henrique Pereira Ramos, Celso Raul Romero Ramos, Paulo Lee Ho, Isabel de Fátima Correia Batista, Ana Marisa Chudzinski‐Tavassi,
Using a cDNA library made from Lonomia obliqua caterpillar bristles, we identified a transcript with a 603 bp open reading frame. The deduced protein corresponds to Lopap, a prothrombin activator previously isolated by our group from the bristles of this species. The mature protein is composed by 185 amino acids and shares similarity with members of the lipocalin family. The cDNA encoding the mature form was amplified by PCR, subcloned into pAE vector and used to transform Escherichia coli BL21( ...
Tópico(s): Venomous Animal Envenomation and Studies
2006 - Portland Press | Biochemical Journal
Produção Nacional
Revisado por pares
Erica Elice Lessa Ferreira, Jabiael Carneiro da Silva Filho, Marília Perrelli Valença, Isabel Cristina Ramos Vieira Santos,
Objective: To verify the prevalence and risk factors associated with urinary incontinence in nulliparous young women. Methods: Integrative literature review, performed by searching the following databases: Medical Literature Analysis and Retrieval System Online (MEDLINE), Latin American and Caribbean Literature in Health Sciences (LILACS), Spanish Bibliographic Index in Health Sciences (IBECS) and in the Nursing Database (BDENF), from March to June 2021, using the descriptors: “urinary incontinence”, “ ...
Tópico(s): Ureteral procedures and complications
2022 - | Revista Estima