John Huxley, Bob Crawley, Margery, Harvey Nichols, Richard Brooks Communications Correspondent, Anne Spackman, Frank Barber, Chris Ryder, Ann Gould, Dewey Gram, George Jones Political Correspondent, Chris Tighe, Liz Sly, Vickie Bramwell, Graham Rose, Mark Lawson, David Steel, Marry Harron, Nick Pitt, Henry Porter, Nigel Harris, Margret Geraghty, Iain Johnstone, Oleg Yartsev, Irwin Stelzer, Peter Godwin, Ivan Fallon, Robert Hewison, David Hellier, Keith Botsford, David Dougill, Barty Philips, John Huxley Energy Editor, Veronica Horwell, L. Parry, Cliff Temple, Jane Bird, Robert Temple, Maria Laura Avignolo, Paul Neild, Sarah Helm, Brian Inglis, Susan Crosland, Edmund Stevens, Kevin Curren, John Ballantine, Anne Jacobs, David Connett, David Taylor, Peter Ackroyd, Rose Shepherd, Byron Rogers, Robin Marlar, Leslie Geddes-Brown, Philip Robinson, Frances Bissell, Bernard Cafferty, Brian Moynahan, Roger Eglin, Tana de Zulueta, Buenos Aires, Michael Nimmo, Peter Shearlock, John Wardroper, J P Stern, Michael Glenny, Paul Driver, James Adams, Sean French, Boris Schapiro, Allen Hall, Richard Brooks, Nicholas Asheshov, George Rosie, Tim Rayment, Michael Imeson, Patrick Marnham, Roger Jowell, John Hopkins, Dr M Levene, Liz Jobey, Eric Marsden, Gareth Huw Davies, Malcolm Winton, Kathy Acker, Anne Boston, Loyd Grossman, Tony Levene, Brian Deer, John Carlin, Jean Michael Jarre, John Ryle, Melvyn Bragg, Bryan Robertson, Louise Nicholson, Guy Playfair, David Lipsey, Dilys Powell, Brough Scott, Deyan Sudjic, Oliver Gillie, Oliver Gillie Medical Correspondent, Henley, Kim Fletcher, Simon Winchester, Felix Aprahamian, Peter Willby, Peter Wilby, John Wilcockson, Sue Summers, Michael Jones Political Editor, Sarah Rutherford, J W Lambert, Robert Scott Chairman, Richard Reeves, Angela Neustatter, Richard Burnell, McEnroe, John Carey, L. Clarke, Grand Prix, Peter Dunn, Noel Coward, Grahum Rose, Colin Clifford, Janet Langmaid, Neil Collins City Editor, Tony Moore, Roy Isacowitz, Christine Whelan, Gordon Bum, Ian Williams, Peter Jenkins, Marina Vaizey, Roger Pye Managing Director, Arthur Ashe, Andrew Graham-Dixon, Tony Hetherington, Neil Collins, Maggie Drummond, Colin Clifford Economics Correspondent, Peter Roebuck, Peter Wilby Education Correspondent, Martina, Ruth Lawrence, Roger Ratcliffe, Jon Connell, Sandy Wilson, Georgina Howell,
... Turkey Multiple Classified Advertising Items Bladon Lines LA Heredia Videovillas The Sunday Times Crossword Spanish Homes Limited ...
1985 - Gale Group | Sunday Times HA GDA
MS Maldonado, Cristina Díaz de Heredia, Isabel Badell, A Muñoz, JJ Ortega, J Cubells, Enrique Otheo, Olive Tengera, Carme Saurina, Jaime Pérez de Oteyza,
The purpose of this study was to evaluate the outcome of children with acute lymphoid leukemia (ALL) in second remission who have undergone high-dose chemotherapy and radiotherapy and autologous bone marrow transplantation (ABMT) with monoclonal antibody purged marrow, and to determine the main prognostic factors. From 1987 to 1992, 55 children with ALL in second remission underwent ABMT. The conditioning regimen consisted of total body irradiation (TBI) plus cyclophosphamide in 21 patients and TBI ...
Tópico(s): Acute Lymphoblastic Leukemia research
1998 - Springer Nature | Bone Marrow Transplantation
Ariana Jacome, Susana Navarro, Paula Rı́o, Rosa María Pérez Yáñez, África González‐Murillo, M. Luz Lozano, María L. Lamana, Julián Sevilla, Teresa Olivé, Cristina Díaz de Heredia, Isabel Badell, Jesús Estella, Luís Madero, Guillermo Güenechea, José Antonio Casado, José C. Segovia, Juan A. Bueren,
Previous clinical trials based on the genetic correction of purified CD34+ cells with γ-retroviral vectors have demonstrated clinical efficacy in different monogenic diseases, including X-linked severe combined immunodeficiency, adenosine deaminase deficient severe combined immunodeficiency and chronic granulomatous disease. Similar protocols, however, failed to engraft Fanconi anemia (FA) patients with genetically corrected cells. In this study, we first aimed to correlate the hematological status ...
Tópico(s): RNA Interference and Gene Delivery
2009 - Elsevier BV | Molecular Therapy
Francisco Molina‐Rueda, Francisco Miguel Rivas Montero, Marta Pérez‐de‐Heredia‐Torres, Isabel María Alguacil Diego, Alberto Molero Sánchez, Juan Carlos Miangolarra Page,
As a result of neurophysiological injury, stroke patients have mobility limitations, mainly on the side of the body contralateral to the lesioned hemisphere. The purpose of this study is to quantify motor compensation strategies in stroke patients during the activity of drinking water from a glass.Four male patient with cerebrovascular disease and four right-handed, healthy male control subjects. The motion analysis was conducted using the Vicon Motion System(®) and surface electromyography equipment ...
Tópico(s): Musculoskeletal pain and rehabilitation
2012 - Elsevier BV | Neurología
Francisco Molina‐Rueda, Francisco Miguel Rivas Montero, Marta Pérez‐de‐Heredia‐Torres, Isabel María Alguacil Diego, Alberto Molero Sánchez, Juan Carlos Miangolarra Page,
As a result of neurophysiological injury, stroke patients have mobility limitations, mainly on the side of the body contralateral to the lesioned hemisphere. The purpose of this study is to quantify motor compensation strategies in stroke patients during the activity of drinking water from a glass. Four male patient with cerebrovascular disease and four right-handed, healthy male control subjects. The motion analysis was conducted using the Vicon Motion System ® and surface electromyography equipment ...
Tópico(s): Botulinum Toxin and Related Neurological Disorders
2012 - Elsevier BV | Neurología (English Edition)
Arturo Muñoz, Cristina Díaz de Heredia, Isabel Badell, E Bureo, Pedro Gómez, A Martínez, Amparo Verdeguer, José María Pérez‐Hurtado, Rafael Fernández‐Delgado, Marta González‐Vicent, María Soledad Maldonado,
Introduction: Experience with the use of allogeneic hemopoietic stem transplantation (AHSCT) in pediatric myelodisplastic syndrome (MDS) in Spain is reviewed. Methods and patients: Twenty-four children with MDS were analyzed retrospectively. Median age of the patients was 10 years. Twenty patients received a bone marrow graft and 4 an unrelated cord blood (UCB) transplant; 12 bone marrow grafts were from a matched related donor (MRD) and 8 from a matched unrelated donor (MUD). Conditioning regimen consisted ...
Tópico(s): Neuroblastoma Research and Treatments
2009 - Taylor & Francis | Pediatric Hematology and Oncology
María I. de Michelena, Luis Miguel Franchi, Percy G. Summers, Carlos De la Fuente, Patricia J. Campos, Jaak Jaeken,
... America Maria Isabel de Michelena, Corresponding Author Maria Isabel de Michelena Institute of Genetics, Universidad Peruana Cayetano Heredia, Lima, PerúDiagonal 340–32, Miraflores, Lima 18, PerúSearch ... author Maria Isabel de Michelena, Corresponding Author Maria Isabel de Michelena Institute of Genetics, Universidad Peruana Cayetano Heredia, Lima, PerúDiagonal 340–32, Miraflores, Lima 18, PerúSearch ...
Tópico(s): Glycosylation and Glycoproteins Research
1999 - Wiley | American Journal of Medical Genetics
Massimo Bogliolo, Roser Pujol, Miriam Aza‐Carmona, Núria Muñoz-Subirana, Benjamín Rodríguez‐Santiago, José Antonio Casado, Paula Rı́o, Christopher Bauser, Judith Reina-Castillón, Marcos López‐Sánchez, Lidia González‐Quereda, P. Gallano, Albert Catalá, Ana Ruiz-Llobet, Isabel Badell, Cristina Díaz de Heredia, Raquel Hladun, Leonort Senent, Bienvenida Argilés, Juan Bergua, Fatima Bañez, Beatriz Arrizabalaga, Ricardo López Almaraz, Monica López, Á Figuera, Antonio Molinés, Inmaculada Pérez de Soto, Inés Hernando, Juan Antonio Muñoz, Maria Marín, Judith Balmañà, Neda Stjepanovic, Estela Carrasco, Isabel Cuesta, José Miguel Cosuelo, Alexandra Regueiro, José M. Moraleda, Ana Maria Galera-Miñarro, Laura Rosiñol, Ana Carrió, Cristina Beléndez‐Bieler, Antonio Escudero Soto, Elena Cela, Gregorio de la Mata, Rafael Fernández‐Delgado, Maria Carmen Garcia-Pardos, Raquel Sáez-Villaverde, Marta Barragaño, Raquel Portugal, Francisco Lendínez, Ines Hernadez, José Manue Vagace, Maria C. Tapia, J. M. Nieto, Marta Garcia, M J Garcia Gonzalez, Cristina Vicho, Eva Heredero Gálvez, Alberto Valiente, María Luisa Antelo, Phil Ancliff, Francisco García‐García, Joaquı́n Dopazo, Julián Sevilla, Tobias Paprotka, Luis A. Pérez‐Jurado, Juan A. Bueren, Jordi Surrallés,
Purpose Patients with Fanconi anaemia (FA), a rare DNA repair genetic disease, exhibit chromosome fragility, bone marrow failure, malformations and cancer susceptibility. FA molecular diagnosis is challenging since FA is caused by point mutations and large deletions in 22 genes following three heritability patterns. To optimise FA patients’ characterisation, we developed a simplified but effective methodology based on whole exome sequencing (WES) and functional studies. Methods 68 patients with FA ...
Tópico(s): Chromosomal and Genetic Variations
2019 - BMJ | Journal of Medical Genetics
Produção Nacional
Revisado por pares
Érika do Carmo Ota, Cláucia Aparecida Honorato, Silvia Cristina Heredia Vieira, Carolina Isabel Flores-Quintana, Tarcila Souza de Castro Silva, L. A. K. A. Inoue, Cláudia Andréa Lima Cardoso,
Tópico(s): Ethnobotanical and Medicinal Plants Studies
2019 - Springer Science+Business Media | Fish Physiology and Biochemistry
Eva Heredero Gálvez, Elena Vallespín, Elena G. Arias‐Salgado, Carmen Sánchez-Valdepeñas, Yari Giménez, Susana Navarro, Paula Rı́o, Massimo Bogliolo, Roser Pujol, Montserrat Peiró, Julián Nevado, Josune Zubicaray, Elena Sebastián, Albert Catalá, Cristina Beléndez, Cristina Díaz de Heredia, A. Galera, Isabel Badell, Luís Madero, Rosario Perona, Leandro Sastre, Jordi Surrallés, Juan A. Bueren, Pablo Lapunzina, Julián Sevilla,
Inherited bone marrow failure syndromes (IBMFSs) are a group of congenital rare diseases characterized by bone marrow failure, congenital anomalies, high genetic heterogeneity, and predisposition to cancer. Appropriate treatment and cancer surveillance ideally depend on the identification of the mutated gene. A next-generation sequencing (NGS) panel of genes could be 1 initial genetic screening test to be carried out in a comprehensive study of IBMFSs, allowing molecular detection in affected patients. ...
Tópico(s): Genomics and Rare Diseases
2021 - Wolters Kluwer | HemaSphere
José María Valle-T-Figueras, Berta Renedo, María Isabel Benítez‐Carabante, Cristina Díaz de Heredia, Jaume Vima Bofarull, Natàlia Mendoza-Palomar, María Teresa Martín-Gómez, Pere Soler‐Palacín,
Voriconazole plasma concentrations (PC) are highly variable, particularly in children. Dose recommendations in 2–12-year-old patients changed in 2012. Little data on therapeutic drug monitoring (TDM) after these new recommendations are available. We aimed to evaluate voriconazole monitoring in children with invasive fungal infection (IFI) after implementation of new dosages and its relationship with safety and effectiveness. A prospective, observational study, including children aged 2–12 years, was ...
Tópico(s): Ocular Infections and Treatments
2021 - Multidisciplinary Digital Publishing Institute | Journal of Fungi
Manuel Castellá, Ramón M. Pujol, Elisabeth Callen, M.J. Ramírez, José Antonio Casado, María Talavera, Teresa Ferró, A. de Arriba Muñoz, Julián Sevilla, Luís Madero, Elena Cela, Cristina Beléndez, Cristina Díaz de Heredia, Olive Tengera, Joan Sánchez-de-Toledo, Isabel Badell, Jesús Estella, Ángeles Dasí, Antonia Rodríguez-Villa, P. Gómez, M. Cruz Tapia, Antonio Molinés, Á Figuera, Juan A. Bueren, Jordi Surrallés,
Background Fanconi anaemia (FA) is a rare syndrome characterized by bone marrow failure, malformations and cancer predisposition. Chromosome fragility induced by DNA interstrand crosslink (ICL)-inducing agents such as diepoxybutane (DEB) or mitomycin C (MMC) is the 'gold standard' test for the diagnosis of FA. Objective To study the variability, the diagnostic implications and the clinical impact of chromosome fragility in FA. Methods Data are presented from 198 DEB-induced chromosome fragility tests in patients ...
Tópico(s): Acute Lymphoblastic Leukemia research
2011 - BMJ | Journal of Medical Genetics
María Castellà, Roser Pujol, Elsa Callén, Juan Pablo Trujillo‐Quintero, José Antonio Casado, Gilles Thomas, Francis P. Lach, Arleen D. Auerbach, Detlev Schindler, Javier Benı́tez, Beatriz Porto, Teresa Ferró, A. de Arriba Muñoz, Julián Sevilla, Luís Madero, Elena Cela, Cristina Beléndez, Cristina Díaz de Heredia, Teresa Olivé, Joan Sánchez-de-Toledo, Isabel Badell, Montserrat Torrent, Jesús Estella, Ángeles Dasí, Antonia Rodríguez-Villa, Pedro Gómez, José Barbot, Maria C. Tapia, Antonio Molinés, Á Figuera, Juan A. Bueren, Jordi Surrallés,
Abstract Fanconi anemia is characterized by congenital abnormalities, bone marrow failure, and cancer predisposition. To investigate the origin, functional role, and clinical impact of FANCA mutations, we determined a FANCA mutational spectrum with 130 pathogenic alleles. Some of these mutations were further characterized for their distribution in populations, mode of emergence, or functional consequences at cellular and clinical level. The world most frequent FANCA mutation is not the result of ...
Tópico(s): Genomics and Rare Diseases
2011 - Elsevier BV | Blood
R.D. Zepeda-Arce, Aurora Elizabeth Rojas‐García, Alma Betsaida Benítez-Trinidad, José Francisco Herrera‐Moreno, Irma Martha Medina‐Díaz, Briscia Socorro Barrón-Vivanco, Germán Pier Villegas, Isabel Hernández‐Ochoa, María de Jesús Sólis Heredia, Yael Yvette Bernal-Hernández,
The indiscriminate use of pesticides in agriculture and public health campaigns has been associated with an increase of oxidative stress and DNA damage, resulting in health outcomes. Some defense mechanisms against free radical-induced oxidative damage include the antioxidant enzyme systems. The aim of this study was to determine the levels of malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), and the relationship of antioxidant ...
Tópico(s): Air Quality and Health Impacts
2017 - Wiley | Environmental Toxicology
Cristina Díaz de Heredia, Juan Ortega, Miguel Ángel Díaz, Olive Tengera, Isabel Badell, Marta González‐Vicent, Joan Sánchez-de-Toledo,
Tópico(s): T-cell and B-cell Immunology
2007 - Springer Nature | Bone Marrow Transplantation
Marta González‐Vicent, Jaime Sanz, José Luís Fuster, Joan Cid, Cristina Díaz de Heredia, Daniel Morillo, José M. Fernández, Antonia Pascual, Isabel Badell, David Serrano, María Laura Fox, Javier de la Serna, Ana Benito, José Miguel Couselo, Blanca Molina, Miguel Ángel Díaz, Miguel Á. Sanz,
Autoimmune hemolytic anemia (AIHA) is a complication of allogeneic hematopoietic stem cell transplantation (HSCT) associated with poor outcome. However, an optimal therapeutic approach is lacking. Between 2000 and 2015, 4099 allogeneic HSCT were performed in eight pediatric centers of the Grupo Español De Trasplante de Medula Osea en Niños (GETMON) and six adult centers of the Grupo Español de Trasplante Hematopoyetico (GETH). Sixty cases of AIHA were registered with a cumulative incidence of 1.5% occurring ...
Tópico(s): Erythrocyte Function and Pathophysiology
2018 - Elsevier BV | Transfusion Medicine Reviews
A Muñoz, Cristina Díaz de Heredia, Miguel Ángel Díaz, Isabel Badell, Amparo Verdeguer, A Martínez, P Gómez, José María Pérez‐Hurtado, Encarnación Bureo, Rafael Fernández‐Delgado, María-Elvira González-Valentín, M. S. Maldonado,
The authors report the results of 58 children with ALL in 2CR after related (n = 31) or unrelated (n = 27) AHSCT. Characteristics at diagnosis and initial and after relapse antileukemic treatment were similar in the related donor (RD) and the unrelated donor (UD) groups. Conditioning consisted of TBI/CY +/- VP-16 for patients > or = 3 years old (n = 43) and Bu/CY for the rest. Median recipient age was 8 years (range 1-17) in the RD and 9 years (range 3-14) in the UD group. Median follow-up was 54 months (range 24-80) ...
Tópico(s): Renal Transplantation Outcomes and Treatments
2008 - Taylor & Francis | Pediatric Hematology and Oncology
Guillermo Ortí, Jaime Sanz, Irene García‐Cadenas, Isabel Sánchez‐Ortega, Laura Alonso, María José Jiménez, Luisa Sisinni, Carmen Azqueta, Olga Salamero, Isabel Badell, Christelle Ferrà, Cristina Díaz de Heredia, Rocío Parody, Miguel Á. Sanz, Jorge Sierra, José Luís Piñana, Sergi Querol, David Valcárcel,
•In this cohort of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) patients, second allogeneic hematopoietic cell transplantation (Allo-HCT) and donor lymphocyte infusion (DLI) showed comparable results.•The time interval from Allo-HCT to relapse is a strong predictor of outcomes for DLI and second Allo-HCT, a shorter time associated with lower overall survival (OS) and disease-free survival (DFS).•Within the DLI cohort, patients receiving T-cell depletion at Allo-HCT had higher OS, ...
Tópico(s): Acute Myeloid Leukemia Research
2018 - Elsevier BV | Experimental Hematology
Nerea Castillo, Irene García‐Cadenas, Pere Barba, Carme Saurina, Cristina Díaz de Heredia, Rodrigo Martino, Christelle Ferrà, Isabel Badell, Izaskun Elorza, Jorge Sierra, David Valcárcel, Sergio Querol,
Highlights•We describe the different lymphocyte subsets kinetics (CD3+, CD4+, CD8+, CD19, and natural killer cells) after transplantation in umbilical cord blood recipients•We studied the predictive factors for each lymphocyte subset recovery after single umbilical cord blood transplantation in adult and pediatric patients•We report different factors that influenced lymphocyte subset recovery after cord blood transplantation: lower antithymocyte globulin dose, negative recipient cytomegalovirus serostatus, ...
Tópico(s): Cytomegalovirus and herpesvirus research
2016 - Elsevier BV | Biology of Blood and Marrow Transplantation
Produção Nacional
Revisado por pares
Luciana Tucunduva, Fernanda Volt, Renato Cunha, Franco Locatelli, Marco Zecca, Akif Yeşilipek, Maurizio Caniglia, Tayfun Güngör, Serap Aksoylar, Franca Fagioli, Yves Bertrand, Maria Carmen Addari, Josu de la Fuente, Jacek Winiarski, Andrea Biondi, Henrik Sengeloev, Isabel Badell, Karin Mellgren, Cristina Díaz de Heredia, Petr Sedláček, Ajay Vora, Vanderson Rocha, Annalisa Ruggeri, Éliane Gluckman,
Summary Umbilical cord blood ( UCB ) from an human leucocyte antigen ( HLA )‐identical sibling can be used for transplantation of patients with malignant and non‐malignant diseases. However, the low cellular content of most UCB units represents a limitation to this approach. An option to increase cell dose is to harvest bone marrow ( BM ) cells from the same donor and infuse them along with the UCB . We studied 156 children who received such a combined graft between 1992 and 2011. Median age was 7 years and 78% ...
Tópico(s): Immune Cell Function and Interaction
2014 - Wiley | British Journal of Haematology
E. Salazar-Arredondo, María de Jesús Solís-Heredia, Elizabeth Rojas‐García, Isabel Hernández‐Ochoa, Betzabet Quintanilla‐Vega,
Extensive use of organophosphorous pesticides (OP) by young men represents a public health problem. Toxicity of OP mainly results in neurotoxicity due to their oxygen analogues (oxons), formed during the OP oxidative activation. OP alter semen quality and sperm chromatin and DNA at different stages of spermatogenesis. Oxons are more toxic than the parent compounds; however, their toxicity to spermatogenic cells has not been reported. We evaluated sperm DNA damage by several OP compounds and their ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2008 - Elsevier BV | Reproductive Toxicology
Jorge Sierra, Salut Brunet, A Grañena, Olive Tengera, Javier Bueno, Josep‐María Ribera, J Petit, Carlos Besses, Andreu Llorente, R. Guardia, J. Maciá, M Rovira, Isabel Badell, Errol Véla, Cristina Díaz de Heredia, P Vivancos, Enric Carreras, Evarist Feliú, Emili Montserrat, Antoni Juliá, J Cubells, C Rozmán, Antònia Domingo‐Salvany, JJ Ortega,
PURPOSE To evaluate prospectively the feasibility and results of bone marrow transplantation (BMT) after induction and intensification chemotherapy (CT) in patients with de novo acute myeloid leukemia (AML). PATIENTS AND METHODS A total of 159 patients less than 51 years of age were treated. Induction CT consisted of daunorubicin 60 mg/m2 for 3 days, cytarabine (ARA-C) 100mg/m2 for 7 days, and etoposide 100 mg/m2 for 3 days. The first intensification therapy included mitoxantrone 10 mg/m2 for 3 days ...
Tópico(s): Hematopoietic Stem Cell Transplantation
1996 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Alberto Heredia, Javier García Guzmán, Antonio de Amescua Seco, Marı́a-Isabel Sánchez-Segura,
This paper defines and validates a solution to support organizational learning through the interactive evolution of organizational knowledge. The approach includes mechanisms to acquire the experiences of individuals working in different teams and environments, combine them with the existing company's knowledge assets, and disseminate the evolved knowledge to all the project teams. This solution was validated in a controlled experiment involving junior engineers in a training course over a two-year ...
Tópico(s): Software Engineering Techniques and Practices
2013 - Institute of Information Science | Journal of information science and engineering
Eva Graciá, Roberto C. Rodríguez‐Caro, M. A. Ferrández, Albert Martı́nez Silvestre, Irene Pérez, Rabie Amahjour, Carmen Aranda, Hadj Aissa Benelkadi, Albert Bertolero, Marta Biaggini, Francisco Botella, Joan Budó, Vanessa Cadenas, Brahim Chergi, Claudia Corti, Fernando Esperón, Miguel Ángel Esteve Selma, Soumía Fahd, Ma Isabel García de la Fuente, Ana Golubović, Ana Heredia, María V. Jiménez‐Franco, Marine Arakelyan, Daniele Marini, Julia Martínez Fernández, Ma Carmen Martínez-Pastor, Ramón Mascort, Andrea Mira‐Jover, Roberto Pascual‐Rico, Anna Perera-Leg, Beate Pfau, Samuel Pinya, Xavier Santos, Amalia Segura, Mohamed Jaouhar Semaha, Joaquim Soler-Massana, J. Leiro, Andrés Giménez,
Chelonians are among the animal groups with the poorest conservation status. Since tortoises are long-lived species that need very long time to reach sexual maturity, they are extremely vulnerable to human pressure. Despite their endangered status, there are no common strategies for the development of conservation actions. At the “Mediterranean workshop to develop tortoise conservation strategies”, scientists, conservation associations, environmental managers, IUCN advisers and CITES inspectors met ...
Tópico(s): Veterinary Pharmacology and Anesthesia
2020 - Asociación Herpetológica Española | Basic and Applied Herpetology
Maura Faraci, Alice Bertaina, Arnaud Dalissier, Marianne Ifversen, Ansgar Schulz, Andrew R. Gennery, Birgit Burkhardt, Isabel Badell, Cristina Díaz de Heredia, Edoardo Lanino, Arjan C. Lankester, Bernd Gruhn, Susanne Matthes‐Martin, Joern S. Kühl, Stefania Varotto, Catherine Paillard, Audrey Guilmatre, Ana Méndez‐Echevarría, Manuel Abecasis, Birgit Garwer, Petr Sedláček, Jaap Jan Boelens, Eric Beohou, Peter Bader,
We report data obtained from a retrospective multicenter pediatric survey on behalf of the European Society for Blood and Marrow Transplantation (EBMT). Information on solid organ transplantation (SOT) performed in pediatric recipients of either autologous or allogeneic hematopoietic stem cell transplantation (HSCT) between 1984 and 2016 was collected in 20 pediatric EBMT Centers (25.6%). Overall, we evaluated data on 44 SOTs following HSCT including 20 liver (LTx), 12 lung (LuTx), 6 heart (HTx), and 6 ...
Tópico(s): Hematopoietic Stem Cell Transplantation
2018 - Elsevier BV | American Journal of Transplantation
Sara Fernández‐Castillejo, Ana‐Isabel García‐Heredia, Rosa Solà, Jordi Camps, Maria‐Carmen López de la Hazas, Marta Farràs, Anna Pedret, Úrsula Catalán, Laura Rubió, Marı́a-José Motilva, Olga Castañer, María‐Isabel Covas, Rosa M. Valls,
Scope Low paraoxonase (PON)1 activities, and high PON1 and low PON3 protein levels are characteristic of cardiovascular disease. Our aim was to assess short‐ and long‐term effects of virgin olive oils (VOO), enriched with their own phenolic compounds (PC; FVOO) or with them plus complementary PC from thyme (FVOOT), on PON‐related variables and the mechanisms involved. Methods and results Two randomized, controlled, double‐blind, and crossover interventions were conducted. In an acute intake study, participants ...
Tópico(s): Cynara cardunculus studies
2017 - Wiley | Molecular Nutrition & Food Research
Sarah E Seaton, Elizabeth S. Draper, Mark Adams, Satoshi Kusuda, Stellan Håkansson, Kjell Helenius, Brian Reichman, Liisa Lehtonen, Dirk Bassler, Shoo K. Lee, Máximo Vento, Brian A. Darlow, Franca Rusconi, Marc Beltempo, Tetsuya Isayama, Kei Lui, Mikael Norman, Junmin Yang, Prakesh S. Shah, Neena Modi, Kei Lui, P. B. MARSHALL, Peter R. Schmidt, Anjali Dhawan, Larissa Korostenski, Javeed Travadi, Mary Sharp, Andy Gill, J. Jane Pillow, Jacqueline Stack, Pita Birch, Karen Nothdurft, Lucy Cooke, Dan Casalaz, Jim Holberton, Alice Stewart, Lyn Downe, Michael Stewart, Andrew Berry, Rod W. Hunt, Peter Morris, Tony De Paoli, Kei Lui, Srinivas Bolisetty, Mary Paradisis, Mark Greenhalgh, Pieter Koorts, Carl A Kuschel, Sue Jacobs, Lex W. Doyle, John Craven, Andrew Numa, Hazel Carlisle, Nadia Badawi, Himanshu Popat, Guan Koh, Jonathan Davis, Melissa Luig, Bevan Headley, Chad Andersen, Linda Ng, Georgina M. Chambers, Nicola Austin, Adrienne Lynn, Brian A. Darlow, Liza Edmonds, Lindsay Mildenhall, Mariam J. Buksh, Malcolm Battin, Jutta van den Boom, Vaughan Richardson, David Barker, B. L. Hammond, Victor Samuel Rajadurai, Simon Ching Lam, Genevieve P. G. Fung, Prakesh S. Shah, Marc Beltempo, Jaideep Kanungo, Joseph Ting, Zenon Cieslak, Rebecca Sherlock, Ayman Abou Mehrem, Jennifer Toye, Khalid Aziz, Carlos Fajardo, Jaya Bodani, Lannae Strueby, Mary Seshia, Deepak Louis, Ruben Alvaro, Amit Mukerji, Orlando da Silva, Mohammad Adie, Kyong‐Soon Lee, Nalini Singhal, Brigitte Lemyre, Thierry Daboval, Faiza Khurshid, Ermelinda Pelausa, Keith J. Barrington, Anie Lapoint, Guillaume Éthier, Christine Drolet, Bruno Piedbœuf, Martine Claveau, Marie St‐Hilaire, Valérie Bertelle, Édith Massé, Roderick Canning, Hala Makary, Cecil Ojah, Luis Monterrosa, Julie Emberley, Jehier Afifi, Andrzej Kajetanowicz, Shoo K. Lee, Marjo Metsäranta, Liisa Lehtonen, Outi Tammela, Ulla Sankilampi, Timo Saarela, Iris Morag, Shmuel Zangen, Tatyana Smolkin, Francis B. Mimouni, David Bader, Avi Rothschild, Zipora Strauss, Clari Felszer, Hussam Omari, Smadar Even Tov‐Friedman, Benjamin Bar‐Oz, Michaël Feldman, Nizar Saad, Orna Flidel‐Rimon, Meir Weisbrod, Daniel Lubin, Ita Litmanovitz, Amir Kugelman, Eric S. Shinwell, Gil Klinger, Yousif Nijim, Alona Bin‐Nun, Agneta Golan, Dror Mandel, Vered Fleisher‐Sheffer, Anat Oron, Lev Bakhrakh, Satoshi Hattori, Masaru Shirai, Toru Ishioka, Toshihiko Mori, Takasuke Amizuka, Toru Huchimukai, Hiroshi Yoshida, Ayako Sasaki, Junichi Shimizu, Toshihiko Nakamura, Mami Maruyama, Hiroshi Matsumoto, Shinichi Hosokawa, Atsuko Taki, Machiko Nakagawa, Kyone Ko, Azusa Uozumi, Setsuko Nakata, Akira Shimazaki, Tatsuya Yoda, Osamu Numata, Hiroaki Imamura, Azusa Kobayashi, Shuko Tokuriki, Yasushi Uchida, Takahiro Arai, Mitsuhiro Ito, Kuniko Ieda, Toshiyuki Ono, Masashi Hayashi, Kanemasa Maki, M Yamakawa, Masahiko Kawai, Noriko Fujii, Kozue Shiomi, Koji Nozaki, Hiroshi Wada, Taho Kim, Yasuyuki Tokunaga, Yasuyuki Tokunaga, Akihiro Takatera, T Oshima, Hiroshi Sumida, Yae Michinomae, Yoshio Kusumoto, Seiji Yoshimoto, Takeshi Morisawa, Tamaki Ohashi, Yukihiro Takahashi, Moriharu Sugimoto, Noriaki Ono, Shinichiro Miyagawa, Takahiko Saijo, Takashi Yamagami, Kosuke Koyano, Shoko Kobayashi, Takeshi Kanda, Yoshihiro Sakemi, Mikio Aoki, Koichi Iida, Mitsushi Goshi, Yuko Maruyama, Alejandro Ávila-Álvarez, José Luis Fernández Trisac, María L. Couce, María José Fernández Seara, Andrés Martínez Gutiérrez, Carolina Vizcaíno, Miriam Salvador Iglesias, Honorio Sánchez Zaplana, Belén Fernández Colomer, José Enrique García López, Rafael García Mozo, Marbelia Martínez, Ma Dolores Muro Sebastián, Marta Balart Carbonell, Joan Badia Barnusell, Mònica Domingo Puiggròs, J. Figueras Aloy, Francesc Botet, Israel Anquela Sanz, Gemma Ginovart, W. Coroleu, Martín Iriondo, Laura Castells Vilella, Roser Porta, Xavier Demestre, S. Martínez-Nadal, Cristina de Frutos Martínez, María Jesús López Cuesta, Dolores Esquivel Mora, J. Ortiz Tardío, Isabel Benavente‐Fernández, Almudena Alonso, Ramón Aguilera Olmos, Miguel A. García Cabezas, Ma Dolores Martínez Jiménez, Ma Pilar Jaraba Caballero, Ma Dolores Ordoñez Díaz, Alberto Trujillo Fagundo, L. Mayol Canals, Fermín García‐Muñoz Rodrigo, Lourdes Urquía Martí, Maria Galdo, José Suazo, E. Narbona López, José Uberos Fernández, Miguel A. Cortajarena Altuna, Oihana Muga Zuriarrain, David Mora Navarro, María Teresa Domínguez, Ma Yolanda Ruiz del Prado, Inés Esteban Díez, María Teresa Palau Benavides, Santiago Lapeña, Teresa Pérez de Prada, Eduard Soler Mir, Araceli Corredera Sánchez, Enrique Criado Vega, Náyade del Prado, Cristina E. Fernández, Lucía Cabanillas Vilaplana, Irene Cuadrado Pérez, Luisa López Gómez, Laura Domingo Comeche, Isabel Llana Martín, C. González Armengod, Carmen Muñoz Labián, Ma José Santos Muñoz, D. Blanco Bravo, Vicente Pérez, Ma Dolores Elorza Fernández, Celia Díaz González, Susana Ares Segura, Manuela López Azorín, Ana Belén Jimenez, Tomás Sánchez‐Tamayo, Elías Tapia Moreno, María Teresa González, José Enrique Sánchez Martínez, José María Lloreda Garcia, Concepción Goñi Orayen, Javier Vilas González, María Suárez Albo, Eva González Colmenero, Elena Pilar Gutiérrez González, Beatriz Vacas del Arco,
To compare length of stay (LOS) in neonatal care for babies born extremely preterm admitted to networks participating in the International Network for Evaluating Outcomes of Neonates (iNeo).Data were extracted for babies admitted from 2014 to 2016 and born at 24 to 28 weeks of gestational age (n = 28 204). Median LOS was calculated for each network for babies who survived and those who died while in neonatal care. A linear regression model was used to investigate differences in LOS between networks after ...
Elsevier BV
Mikael Norman, Stellan Håkansson, Satoshi Kusuda, Máximo Vento, Liisa Lehtonen, Brian Reichman, Brian A. Darlow, Mark Adams, Dirk Bassler, Tetsuya Isayama, Franca Rusconi, Shoo Lee, Kei Lui, Junmin Yang, Prakesh S. Shah, Kei Lui, P. B. MARSHALL, Péter Schmidt, Anjali Dhawan, P. D. Craven, Koert de Waal, Karen Simmer, Andy Gill, J. Jane Pillow, Jacqueline Stack, Pita Birch, Lucy Cooke, Dan Casalaz, Jim Holberton, Alice Stewart, Lyn Downe, Michael J. Stewart, Barbara Bajuk, Andrew Berry, Rod W. Hunt, Charles Kilburn, Tony De Paoli, Kei Lui, Srinivas Bolisetty, Mary Paradisis, Ingrid Rieger, Pieter Koorts, Carl A Kuschel, Lex W. Doyle, Andrew Numa, Hazel Carlisle, Nadia Badawi, Alison Loughran‐Fowlds, Guan Koh, Jonathan Davis, Melissa Luig, Chad Andersen, Georgina M. Chambers, Nicola Austin, Adrienne Lynn, Brian A. Darlow, Liza Edmonds, Lindsay Mildenhall, Mariam J. Buksh, Malcolm Battin, Jutta van den Boom, D Bourchier, Vaughan Richardson, Fiona Dineen, Victor Samuel Rajadurai, Simon Ching Lam, Genevieve P. G. Fung, Prakesh S. Shah, Adele Harrison, Anne Synnes, Joseph Ting, Zenon Cieslak, Rebecca Sherlock, Wendy Yee, Khalid Aziz, Jennifer Toye, Carlos Fajardo, Zarin Kalapesi, Koravangattu Sankaran, Sibasis Daspal, Mary Seshia, Ruben Alvaro, Amit Mukerji, Orlando da Silva, Chuks Nwaesei, Kyong‐Soon Lee, Michael Dunn, Brigitte Lemyre, Kimberly Dow, Ermelinda Pelausa, Keith J. Barrington, Christine Drolet, Bruno Piedbœuf, Martine Claveau, Marc Beltempo, Valérie Bertelle, Édith Massé, Roderick Canning, Hala Makary, Cecil Ojah, Luis Monterrosa, Akhil Deshpandey, Jehier Afifi, Andrzej Kajetanowicz, Shoo K. Lee, Sture Andersson, Liisa Lehtonen, Outi Tammela, Ulla Sankilampi, Timo Saarela, Eli Heymann, Shmuel Zangen, Tatyana Smolkin, Francis B. Mimouni, David Bader, Avi Rothschild, Zipora Strauss, Clari Felszer, Hussam Omari, Smadar Even Tov‐Friedman, Benjamin Bar‐Oz, Michaël Feldman, Nizar Saad, Orna Flidel‐Rimon, Meir Weisbrod, Daniel Lubin, Ita Litmanovitz, Amir Kugelman, Eric S. Shinwell, Gil Klinger, Yousif Nijim, Alona Bin‐Nun, Agneta Golan, Dror Mandel, Vered Fleisher‐Sheffer, David Kohelet, Lev Bakhrakh, Satoshi Hattori, Masaru Shirai, Toru Ishioka, Toshihiko Mori, Takasuke Amizuka, Toru Huchimukai, Hiroshi Yoshida, Ayako Sasaki, Junichi Shimizu, Toshihiko Nakamura, Mami Maruyama, Hiroshi Matsumoto, Shinichi Hosokawa, Atsuko Taki, Machiko Nakagawa, Kyone Ko, Azusa Uozumi, Setsuko Nakata, Akira Shimazaki, Tatsuya Yoda, Osamu Numata, Hiroaki Imamura, Azusa Kobayashi, Shuko Tokuriki, Yasushi Uchida, Takahiro Arai, Mitsuhiro Ito, Kuniko Ieda, Toshiyuki Ono, Masashi Hayashi, Kanemasa Maki, M Yamakawa, Masahiko Kawai, Noriko Fujii, Kozue Shiomi, Koji Nozaki, Hiroshi Wada, Taho Kim, Yasuyuki Tokunaga, Akihiro Takatera, T Oshima, Hiroshi Sumida, Yae Michinomae, Yoshio Kusumoto, Seiji Yoshimoto, Takeshi Morisawa, Tamaki Ohashi, Yukihiro Takahashi, Moriharu Sugimoto, Noriaki Ono, Shinichiro Miyagawa, Takahiko Saijo, Takashi Yamagami, Kosuke Koyano, Shoko Kobayashi, Takeshi Kanda, Yoshihiro Sakemi, Mikio Aoki, Koichi Iida, Mitsushi Goshi, Yuko Maruyama, Alejandro Ávila-Álvarez, José Luis Fernández Trisac, María L. Couce, María José Fernández Seara, Andrés Martínez Gutiérrez, Carolina Vizcaíno, Miriam Salvador Iglesias, Honorio Sánchez Zaplana, Belén Fernández Colomer, José Enrique García López, Rafael García Mozo, Marbelia Martínez, Ma Dolores Muro Sebastián, Marta Balart Carbonell, Joan Badia Barnusell, Mònica Domingo Puiggròs, Corporacio Parc Taulí, J. Figueras Aloy, Francesc Botet, Israel Anquela Sanz, Gemma Ginovart, Hermina Sánta, W. Coroleu, Martín Iriondo, Laura Castells Vilella, Roser Porta, Xavier Demestre, S. Martínez-Nadal, Cristina de Frutos Martínez, María Jesús López Cuesta, Dolores Esquivel Mora, J. Ortiz Tardío, Isabel Benavente‐Fernández, Almudena Alonso, Ramón Aguilera Olmos, Miguel A. García Cabezas, Ma Dolores Martínez Jiménez, Ma Pilar Jaraba Caballero, Ma Dolores Ordoñez Díaz, Alberto Trujillo Fagundo, L. Mayol Canals, Fermín García‐Muñoz Rodrigo, Lourdes Urquía Martí, Maria Galdo, José Suazo, E. Narbona López, José Uberos Fernández, Miguel A. Cortajarena Altuna, Oihana Muga Zuriarrain, David Mora Navarro, María Teresa Domínguez, Ma Yolanda Ruiz del Prado, Inés Esteban Díez, María Teresa Palau Benavides, Santiago Lapeña, Teresa Pérez de Prada, Eduard Soler Mir, Araceli Corredera Sánchez, Enrique Criado Vega, Náyade del Prado, Cristina E. Fernández, Lucía Cabanillas Vilaplana, Irene Cuadrado Pérez, Luisa López Gómez, Laura Domingo Comeche, Isabel Llana Martín, C. González Armengod, Carmen Muñoz Labián, Ma José Santos Muñoz, D. Blanco Bravo, Vicente Pérez, Ma Dolores Elorza Fernández, Celia Díaz González, Susana Ares Segura, Manuela López Azorín, Ana Belén Jimenez, Tomás Sánchez‐Tamayo, Elías Tapia Moreno, María Teresa González, José Enrique Sánchez Martínez, José María Lloreda Garcia, Concepción Goñi Orayen, Javier Vilas González, María Suárez Albo, Eva González Colmenero, Elena Pilar Gutiérrez González, Beatriz Vacas del Arco, Josefina Márquez Fernández, L. Acosta Gordillo, Mercedes Granero Asensio, Carmen Macías Díaz, Mar Albújar, Pedro Fuster Jorge, Sabina Romero, Mónica Rivero Falero, Ana Belén Escobar Izquierdo, Javier Estañ-Capell, Ma Isabel Izquierdo Macián,
Background Very preterm infants are at high risk of death or severe morbidity. The objective was to determine the significance of severe congenital heart defects (CHDs) for these risks. Methods and Results This cohort study included infants from 10 countries born from 2007-2015 at 24 to 31 weeks' gestation with birth weights <1500 g. Severe CHDs were defined by International Classification of Diseases, Ninth Revision (ICD-9) and Tenth (ICD-10) codes and categorized as those compromising systemic output, ...
Wiley
Mayrut Urióstegui-Acosta, Isabel Hernández‐Ochoa, María de Jesús Solís-Heredia, Gerardo Martínez‐Aguilar, Betzabet Quintanilla‐Vega,
Methamidophos (MET), widely used in developing countries, is a highly neurotoxic organophosphate pesticide that has been associated with male reproductive alterations. Commercial formulations of pesticides used by agricultural workers and urban sprayers are responsible for thousands of intoxications in developing countries and may not have the same effects as active pure ingredients. Therefore, we compared effects of MET technical (METt) and commercial (METc) grades on sperm quality and DNA integrity. ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2012 - Wiley | Environmental Toxicology
Javier Hueto Pérez de Heredia, Pilar Cebollero Rivas, José Antonio Cascante Rodrigo, Isabel Andrade Vela, I. Pascal Martínez, Joan Boldú Mitjans, Víctor Manuel Eguía Astibia,
To analyze the results obtained in a lung cancer (LC) screening program since its inception five years ago regarding correct referrals, diagnostic and therapeutic delay times and days of hospitalization. To compare the diagnostic–therapeutic delays and hospital stays with those obtained in patients evaluated with the standard system. Included for study were all those patients evaluated in our lung cancer screening program (LCSP) in the last five years. For the cases with LC, we recorded the dates ...
Tópico(s): Lung Cancer Research Studies
2012 - Elsevier BV | Archivos de Bronconeumología