Charles Galdies, R. Bellerby, Donata Melaku Canu, Wenting Chen, E. García‐Luque, Blaženka Gašparović, Jelena Godrijan, Paul Lawlor, Frank Maes, Alenka Malej, Dionisios Panagiotaras, Beatriz Martínez Romera, Claire E. Reymond, Julien Rochette, Cosimo Solidoro, Robert Stojanov, Rachel Tiller, Isabel Torres de Noronha, Grzegorz Uścinowicz, Natașa Văidianu, Cormac Walsh, Roberta Guerra,
Ocean acidification (OA) is a global problem with profoundly negative environmental, social and economic consequences. From a governance perspective, there is a need to ensure a coordinated effort to directly address it. This study reviews 90 legislative documents from 17 countries from the European Economic Area (EEA) and the UK that primarily border the sea. The primary finding from this study is that the European national policies and legislation addressing OA is at best uncoordinated. Although ...
Tópico(s): Coral and Marine Ecosystems Studies
2020 - Elsevier BV | Marine Policy
Produção Nacional
Revisado por pares
Jociene Terra da Penha, Fernanda Carneiro Mussi, Cecília Noronha de Miranda Carvalho, Isabel Rey, Flávio Rodrigues‐Júnior, Elisabeth de Amorim Machado, Fernando Lencastre Sicuro, Paulo Farinatti, Eliete Bouskela, Paulo Ferrez Collett‐Solberg,
The prevalence of obesity is increasing. The aim of this study was to investigate if there is endothelial dysfunction in children with normal or excess weight, and whether the metabolic profile, adipokines, and endothelial dysfunction would be more strongly associated with physical fitness or with physical activity levels.Cross-sectional study involving children aged 5-12 years. The evaluation included venous occlusion plethysmography, serum levels of adiponectin, leptin and insulin, lipid profile, ...
Tópico(s): Physical Activity and Health
2018 - Elsevier BV | Jornal de Pediatria
Produção Nacional
Isabel Rey, Cecília Noronha de Miranda Carvalho, Fernanda Carneiro Mussi, Haroldo José de Matos, Marcos Antônio Borges, Maria Alice Neves Bordallo,
To establish, among the cut-off values for the homeostatic model assessment for insulin resistance index (HOMA-IR) cited in the literature, the best in identifying metabolic syndrome (MS) in obese and overweight children.A total of 106 pre-pubertal children were studied. The definition of MS was adapted from that of the International Diabetes Federation. For each cut-off values for HOMA-IR, it was estimated sensibility and specificity for MS. A receiver operating characteristic (ROC) curve was generated ...
Tópico(s): Gestational Diabetes Research and Management
2008 - Editora da Universidade de São Paulo | Arquivos Brasileiros de Endocrinologia & Metabologia
Produção Nacional
Revisado por pares
Samantha Torres Grams, Lariane Mortean Ono, Marcos de Noronha, Camila Isabel Santos Schivinski, Elaine Paulin,
BACKGROUND: There is currently no consensus on the indication and benefits of breathing exercises for the prevention of postoperative pulmonary complications PPCs and for the recovery of pulmonary mechanics. OBJECTIVE: To undertake a systematic review of randomized and quasi-randomized studies that assessed the effects of breathing exercises on the recovery of pulmonary function and prevention of PCCs after upper abdominal surgery UAS. METHOD: Search Strategy: We searched the Physiotherapy Evidence ...
Tópico(s): Obstructive Sleep Apnea Research
2012 - Elsevier BV | Brazilian Journal of Physical Therapy
Isabel Rey, Cecília Noronha de Miranda Carvalho, Fernanda Carneiro Mussi, Liana Wernersbach Pinto, Marcos Antônio Borges, Maria Alice Neves Bordallo,
ativa (HAART), acompanhadas na Santa Casa de São Paulo (SP).A genotipagem foi realizada com produtos purificados de reação em cadeia da polimerase (PCR) de RNA retrotranscrito, utilizando-se o kit comercial Viroseq HIV-1 Genotyping System 2.0 ou a técnica de nested PCR in-house.O sequenciamento foi
Tópico(s): Adipose Tissue and Metabolism
2009 - Elsevier BV | Jornal de Pediatria
Produção Nacional
Revisado por pares
Maria Augusta Montenegro, Fernando Cendes, Ana L.A. Noronha, Susana Barreto Mory, Maria Isabel Brasil de Carvalho, Lúcia Helena Neves Marques, Carlos A.M. Guerreiro,
Clobazam (CLB) has an important antiepileptic effect and is less expensive than the new antiepileptic drugs (AEDs), but still has not been considered as first-line drug in the treatment of epilepsy. We evaluated the efficacy of CLB as add-on therapy in patients with refractory partial epilepsy.This was an open, retrospective study, conducted at the epilepsy clinic of our university hospital. All patients had chronic epilepsy and were being evaluated for epilepsy surgery. CLB was introduced as add- ...
Tópico(s): Neuroscience and Neuropharmacology Research
2001 - Wiley | Epilepsia
Produção Nacional
Revisado por pares
Fernanda Carneiro Mussi, Maria Alice Neves Bordallo, Isabel Rey, Cecília Noronha de Miranda Carvalho, Alexandra Monteiro, Nádia Cristina Pinheiro Rodrigues, Marcos Antônio Borges, Paulo Ferrez Collett‐Solberg, Bruna Moreira Muniz, Cecília Lacroix de Oliveira, Suellen Martins Pinheiro, Rebeca Ribeiro,
Abstract Early exposure to cardiovascular risk factors creates a chronic inflammatory state that could damage the endothelium followed by thickening of the carotid intima-media. To investigate the association of cardiovascular risk factors and thickening of the carotid intima Media in prepubertal children. In this cross-sectional study, carotid intima-media thickness (cIMT) and cardiovascular risk factors were assessed in 129 prepubertal children aged from 5 to 10 year. Association was assessed by ...
Tópico(s): Nutritional Studies and Diet
2015 - De Gruyter | Journal of Pediatric Endocrinology and Metabolism
Produção Nacional
Revisado por pares
Isabel Rey, Cecília Noronha de Miranda Carvalho, Fernanda Carneiro Mussi, Liana Wernersbach Pinto, Marcos Antônio Borges, Maria Alice Neves Bordallo,
OBJETIVO: Verificar o impacto da obesidade sobre os componentes da síndrome metabólica e sobre os níveis de adipocitoquinas em crianças pré-púberes. MÉTODOS: Estudo transversal comparando 30 crianças obesas, 31 com sobrepeso e 33 eutróficas, oriundas do ambulatório de pediatria geral de um hospital universitário, quanto às médias de glicose, lipídios séricos, insulina, HOMA-IR (homeostasis model assessment-insulin resistance), relação glicose/insulina, adiponectina e leptina. Compararam-se as frequências ...
Tópico(s): Indigenous Health and Education
2009 - Elsevier BV | Jornal de Pediatria
Susana Isabel de Castro Santos do Canto De Noronha, Yue Chen, Marin Sekosan,
Tópico(s): Bacterial Identification and Susceptibility Testing
1996 - Lippincott Williams & Wilkins | Obstetrics and Gynecology
Produção Nacional
Revisado por pares
Tiago Palladino Delforno, Gileno Vieira Lacerda-Júnior, Melline Fontes Noronha, Isabel Kimiko Sakamoto, Maria Bernadete Amâncio Varesche, Valéria Maia de Oliveira,
Abstract The 16S r RNA gene amplicon and whole‐genome shotgun metagenomic ( WGSM ) sequencing approaches were used to investigate wide‐spectrum profiles of microbial composition and metabolic diversity from a full‐scale UASB reactor applied to poultry slaughterhouse wastewater treatment. The data were generated by using MiSeq 2 × 250 bp and HiSeq 2 × 150 bp Illumina sequencing platforms for 16S amplicon and WGSM sequencing, respectively. Each approach revealed a distinct microbial community profile, with ...
Tópico(s): Bacteriophages and microbial interactions
2017 - Wiley | MicrobiologyOpen
Mónica Inés, Teresa Coelho, Isabel Conceição, Lara Noronha Ferreira, Mamede de Carvalho, João Costa,
Abstract Background Hereditary Transthyretin Amyloidosis Polyneuropathy is a rare life-threatening neurologic disease that imposes considerable mortality and it is associated with progressive related disabilities. In this study, we aimed to assess the effect of the disease across health-related quality of life dimensions, in both carriers of the mutation and patients, to compare health-related quality of life with general population, as well as to explore health-related quality of life prognostic ...
Tópico(s): Parathyroid Disorders and Treatments
2020 - BioMed Central | Orphanet Journal of Rare Diseases
Produção Nacional
Revisado por pares
Vanessa Pepino, José Dirceu Ribeiro, Maria Ângela Gonçalves de Oliveira Ribeiro, Marcos de Noronha, Maria Aparecida Mezzacappa, Camila Isabel Santos Schivinski,
Objective This study reviewed the scientific evidence available on the effects of manipulative techniques on children with respiratory diseases. Method Three databases (SciELO, PEDro, and MEDLINE) were searched for clinical trials on the effects of manual therapy techniques on children and adolescents with respiratory diseases. The relevant studies were chosen by 2 independent researchers who assessed their abstracts and selected the studies that met the criteria for a complete and structured review. ...
Tópico(s): Pediatric health and respiratory diseases
2013 - Elsevier BV | Journal of Manipulative and Physiological Therapeutics
Produção Nacional
Revisado por pares
Flávia Noronha Dutra Ribeiro, Arissa Sary Umezaki, Júlio Barboza Chiquetto, Isabel Kinney Ferreira de Miranda Santos, Pedro Gerber Machado, Regina Maura de Miranda, Paulo Santos de Almeida, André Felipe Simões, Dominique Mouette, Alexandre Ribeiro Leichsenring, Helene Mariko Ueno,
The present work aims to estimate future transportation scenarios for the Metropolitan Region of Sao Paulo, Brazil, and test their potential to abate air pollutants, greenhouse gases and heat emissions from vehicular activity. The estimations were performed for 2028 and 2038, using the State Environmental Agency's official methodology and the fleet evolution was calculated using recent trends. The tested abatement scenarios comprise changes in fuels in light-duty vehicles, buses and trucks, in engine ...
Tópico(s): Atmospheric chemistry and aerosols
2021 - Elsevier BV | The Science of The Total Environment
Produção Nacional
Revisado por pares
Luciani Gaspar de Toledo, Matheus Aparecido dos Santos Ramos, Patrícia Bento da Silva, Camila Fernanda Rodero, Veridiana de Sá Gomes, Anderson Noronha da Silva, Fernando R. Pavan, Isabel C. Silva, Fernando Bombarda Oda, Danilo Luiz Flumignan, André Gonzaga dos Santos, Marlus Chorilli, Margarete Teresa Gottardo de Almeida, Taís Maria Bauab,
Purpose: Vulvovaginal candidiasis (VVC) is an opportunistic fungal infection that adversely affects a woman's health, due to unpleasant symptoms, therapeutic challenges, and the emergence of resistant strains. The association of natural products and nanotechnology is important to improve the antifungal potential of medicinal plants. We aimed to evaluate the in vitro and in vivo anti- Candida albicans activity of unloaded (EO) and loaded (ME+EO) essential oil of Cymbopogon nardus in the microemulsion ( ...
Tópico(s): Herbal Medicine Research Studies
2020 - Dove Medical Press | International Journal of Nanomedicine
Produção Nacional
Revisado por pares
Isabel Rey, Maria Alice Neves Bordallo, Cecília Noronha de Miranda Carvalho, Fernanda Carneiro Mussi, Flavio Moutinho de Souza, Haroldo José de Matos, Marcos Antônio Borges,
Objective: Insulin resistance has a central role in the pathophysiology of cardiovascular atherosclerotic disease. Adipose tissue is of capital importance in view of its production of adipokines. The present study aims to determine the association of metabolic syndrome components, which constitute risk factors for cardiovascular atherosclerotic disease, and leptin and adiponectin with insulin resistance in prepubertal children.
Tópico(s): Adipose Tissue and Metabolism
2011 - De Gruyter | Journal of Pediatric Endocrinology and Metabolism
Produção Nacional
Revisado por pares
Renata Tavares de Souza Cabral, Evandro Mendes Klumb, Maria Isabel Noronha Neta Couto, Sueli Carneiro,
Purpose: To investigate the frequency of toxic retinopathy in patients with lupus erythematosus and rheumatoid arthritis with long-term use of chloroquine diphosphate or hydroxychloroquine through spectral domain optical coherence tomography and the outcomes of ophthalmological exams (visual acuity - Snellen's table, color vision test - Ishihara's table, fundoscopy, and retinography - red-free). Methods: A cross-sectional study was carried out involving the ophthalmologic evaluation of patients using regular ...
Tópico(s): Systemic Lupus Erythematosus Research
2019 - Conselho Brasileiro de Oftalmologia | Arquivos Brasileiros de Oftalmologia
Produção Nacional
Isabel Fernandes de Oliveira, Nívia Lúcia de Andrade Oliveira, Marília Noronha Costa do Nascimento, Rafaella Lopes Araújo, Fellipe Coelho‐Lima, Keyla Mafalda de Oliveira Amorim,
Analisa-se a atuação do psicólogo em Centros de Referência da Assistência Social (CRAS) localizados em municípios do interior do estado do Rio Grande do Norte (RN). Quinze psicólogos de CRAS distribuídos nas microrregiões do RN foram entrevistados, a partir de um roteiro semiestruturado sobre perfil sociodemográfico, formação profissional, serviços ofertados nos CRAS e atividades desenvolvidas pelos psicólogos. Identificou-se que esses profissionais realizam um conjunto de atividades, que tanto atende ...
Tópico(s): Social and Economic Solidarity
2014 - Associação Brasileira de Psicologia Social | Psicologia & Sociedade
Produção Nacional
Revisado por pares
Virgínia Januário, Dione Augusto de Ávila, Maria Alice Penetra, Ana Luísa Sampaio, Maria Isabel Noronha Neta, Flávia de Freire Cassia, Sueli Carneiro,
Among the chronic leg ulcers, venous ulcers are the most common and constitute a major burden to public health. Despite all technology available, some patients do not respond to established treatments. In our study, carboxymethylcellulose was tested in the treatment of refractory chronic venous ulcers.To evaluate the efficacy of carboxymethylcellulose 20% on the healing of chronic venous ulcers refractory to conventional treatments.This is an analytical, pre-experimental study. Thirty patients were ...
Tópico(s): Diabetic Foot Ulcer Assessment and Management
2016 - Elsevier BV | Anais Brasileiros de Dermatologia
Produção Nacional
Isabel Rey, Maria Alice Neves Bordallo, Nádia Cristina Pinheiro Rodrigues, Cecília Noronha de Miranda Carvalho, Fernanda Carneiro Mussi, Paulo Ferrez Collett‐Solberg, Clarice Medeiros, Ana Paula Bordallo, Marcos Antônio Borges, Cláudia Braga Monteiro, Rebeca Ribeiro,
Leptin has been suggested as a potential biomarker of cardiovascular risk. This paper aims to ascertain, based on a sample of prepubertal children, which serum leptin value best suited to identify metabolic syndrome (MS).This observational, cross-sectional study recruited children from the outpatient pediatrics clinic, with the purpose of validating serum leptin level cutoffs to identify MS. All obese and overweight children who met eligibility criteria were included in the study, as was a sample ...
Tópico(s): Adipose Tissue and Metabolism
2016 - Brazilian Society of Endocrinology and Metabolism | Archives of Endocrinology and Metabolism
Produção Nacional
Revisado por pares
Arine Santos Peçanha, Alexandra Monteiro, Fernanda Carneiro Mussi, Isabel Rey, Maria Alice Neves Bordallo, Cecília Noronha de Miranda Carvalho, Luciana Tricai Cavalini,
Abstract.To evaluate, using ultrasound, the distribution of abdominal fat in obese prepubertal children, as well as its possible correlation with metabolic changes due to obesity.This was a cross-sectional study of prepubescent children: 77 obese children (33 girls and 44 boys), with a mean age of 7.31 years; and 31 normal-weight children (17 girls and 14 boys), with a mean age of 7.32 years. In all of the children, abdominal wall thickness (AWT) and abdominal fat thickness (AFT) were measured by ultrasound. ...
Tópico(s): Body Composition Measurement Techniques
2018 - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem | Radiologia Brasileira
M. Alexandrina Timóteo, Inês Carneiro, Isabel Silva, José Bernardo Noronha‐Matos, Fátima Ferreirinha, Miguel Silva‐Ramos, Paulo Correia‐de‐Sá,
In contrast to the well-known signaling role of urothelial ATP to control bladder function, the hypothesis that uracil nucleotides (UTP and/or UDP) also exert autocrine/paracrine actions only recently gained experimental support. Urothelial cells express UDP-sensitive P2Y6 receptors, yet their role in the control of bladder activity has been mostly neglected. This study was designed to investigate the ability of PSB0474, a stable UDP analogue which exhibits selectivity for P2Y6 receptors, to modulate ...
Tópico(s): Adenosine and Purinergic Signaling
2013 - Elsevier BV | Biochemical Pharmacology
Tópico(s): Libraries, Manuscripts, and Books
2000 - Fundação Oswaldo Cruz, Casa de Oswaldo Cruz | História Ciências Saúde-Manguinhos
Produção Nacional
Revisado por pares
Laura Oliveira, Ana Costa, José Bernardo Noronha‐Matos, Isabel Silva, Walter Luís Garrido Cavalcante, M. Alexandrina Timóteo, A.P. Corrado, Cháriston André Dal Belo, Célia Regina Ambiel, Wilson Alves‐Do‐Prado, Paulo Correia‐de‐Sá,
The mechanisms underlying improvement of neuromuscular transmission deficits by glucocorticoids are still a matter of debate despite these compounds have been used for decades in the treatment of autoimmune myasthenic syndromes. Besides their immunosuppressive action, corticosteroids may directly facilitate transmitter release during high-frequency motor nerve activity. This effect coincides with the predominant adenosine A2A receptor tonus, which coordinates the interplay with other receptors (e. ...
Tópico(s): Peripheral Neuropathies and Disorders
2014 - Elsevier BV | Neuropharmacology
Alice Balbé, Elaine Trindade, Isabel Moreira Macedo,
... da unidade popular, de Camilo de Sousa e Isabel de Noronha. A análise documental exploratória (Wolff, 2004) indica que ...
Tópico(s): African history and culture studies
2021 - University of Minho | Vista
Produção Nacional
Isabel Fernandes de Oliveira, Keyla Mafalda Oliveira Amorim, Rafaele A. Paiva, Kamilla Sthefany A. Oliveira, Marilia Noronha C. Nascimento, Rafaella Lopes Araújo,
Núcleos de Apoio à Saúde da Família' aim to raise the resolution, range and scope of the Family Health Strategy and it is structured in nine strategic areas, among which mental health.Through it, psychologists occupy a prominent space in teams whose work should prioritize the matrix support.This research aimed to analyze the psychological practice in those health teams in Rio Grande do Norte, Brazil, regarding to adopted role models and their consistency with the principles of public health system ...
Tópico(s): Education Pedagogy and Practices
2017 - | Temas em Psicologia
Raed Zakout, M de O Fonseca, João Meneses Santos, A.P. Marques, Isabel Távora, Emília Oliveira, Carlos Noronha Ferreira, Rui M. M. Victorino,
Aseptic liver abscesses preceding the diagnosis of Crohn's disease are extremely rare. We report a patient with multiple liver abscesses that yielded negative microbiologic investigation and failed to develop full remission under antibiotic therapy. Diagnosis of Crohn's disease of small and large bowel was later established and she was started on sulfasalazine and azathioprine with total regression of the hepatic abscesses. This case illustrates the rare possibility of aseptic liver abscesses as ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2009 - Lippincott Williams & Wilkins | Diseases of the Colon & Rectum
Produção Nacional
Revisado por pares
Mariana Bento Tatara, João Perdigão, Miguel Viveiros, Afrânio Lineu Kritski, Késia Esther da Silva, Flávia Patussi Correia Sacchi, Camila Camioli de Lima, Paulo César Pereira dos Santos, Jaciara Diniz, Pedro Eduardo Almeida da Silva, Pedro Gomes, Mônica Maria Quirino Gomes, Eunice Atsuko Totumi Cunha, José Roberto Lapa e Silva, Isabel Portugal, Júlio Croda, Mônica Kramer de Noronha Andrade,
National border areas are special places for the spread of Mycobacterium tuberculosis (MTB). These regions concentrate vulnerable populations and constant population movements. Understanding the dynamics of the transmission of MTB is fundamental to propose control measures and to monitor drug resistance. We conducted a population-based prospective study of tuberculosis (TB) to evaluate molecular characteristics of MTB isolates circulating in Roraima, a state on the border of Venezuela and Guyana. ...
Tópico(s): Infectious Diseases and Tuberculosis
2019 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Maria Isabel Noronha, Manuel Alves Rodrígues,
A percepção que as crianças têm sobre a sua própria saúde é um importante indicador para a definição de estratégias de promoção de saúde infantil. Este estudo correlacional analisa a percepção de saúde de uma amostra probabilística acidental de 216 crianças portuguesas do ensino básico. O questionário de recolha de dados (CHIP-CE) revelou boas propriedades psicométricas (alfa=0,84). Os resultados indicam médias e desvios-padrão de cinco fatores: Conforto (4,34; 0,45); Evitamento de risco (4,18; 0,53); ...
Tópico(s): Resilience and Mental Health
2011 - UNIVERSIDADE FEDERAL DO RIO DE JANEIRO | Escola Anna Nery
Carmen Lúcia Tindó Ribeiro Secco,
... na memoria e nas tradicoes. A narrativa cinematografica de Isabel Noronha entendida como travessia dialogica por tematicas, estruturas e linguagens ligadas nao so a construcoes identitarias e sociais relacionadas ao contexto mocambicano – em particular ao universo mitico ronga –, como tambem a vida e obra de Malangatana Valente e a ficcao poetica de Mia ...
Tópico(s): Urban Development and Societal Issues
2016 - UNIVERSIDADE ESTADUAL DE MONTES CLAROS | Revista Cerrados
Mónica Inés, Teresa Coelho, Isabel Conceição, Lara Noronha Ferreira, Mamede de Carvalho, João Costa,
Background Transthyretin Familial Amyloid Polyneuropathy (TTRFAP) is a rare, progressive, debilitating and life-threatening neurodegenerative disease. The purpose of this study was to assess the health-related quality of life (HRQoL) impairment of TTR-FAP disease versus Portuguese general population and to identify individual patient characteristics such as disease stage – that affects their HRQoL. Literature on TTR-FAP patients HRQoL is scarce at worldwide level and no evidence for Portugal has been ...
Tópico(s): Cellular transport and secretion
2015 - BioMed Central | Orphanet Journal of Rare Diseases