... Gelehrte Anzeigen. Essay: Tmone Eie Iein, Hymnus in Isim. Ab Ludovico Rossio Repertum Primum Distinxit Emendavit Annotavit ...
1843 - Gale Group | NCCO SciTechMed 2 of 2
Ankit Patel, Takaaki Oba, Ryutaro Kajihara, Toshihiro Yokoi, Scott I. Abrams, Fumito Ito,
... minimizing systemic toxicities. A combinatorial in situ immunomodulation (ISIM) regimen with intratumoral administration of Fms-like tyrosine ... T cell–inflamed tumors. However, the impact of ISIM on myeloid-derived suppressor cells (MDSCs), which may ... CD11b+Ly-6ChiLy-6G− monocytic (M)–MDSCs in ISIM-treated tumors using mouse models of triple-negative breast cancer. We found that ISIM treatment decreased intratumoral PMN-MDSCs, but not M- ... Although the frequency of M-MDSCs remained unchanged, ISIM caused a substantial reduction of CX3CR1+ M-MDSCs ...
Tópico(s): Glioma Diagnosis and Treatment
2021 - American Association of Immunologists | The Journal of Immunology
Pamela S. Davila, Brent J. Bos, E. S. Cheng, Bill Chang, William L. Eichhorn, Bradley J. Frey, Mario S. Garza, Qian Gong, Bradford W. Greeley, Jeff Guzek, Claef Hakun, L. Hovmand, Jeff Kirk, David A. Kubalak, Douglas B. Leviton, Adrian F. Nagle, Rich Nyquist, Thai Pham, Frederick D. Robinson, Derek Sabatke, Joseph Sullivan, Paul Volmer, Rob VonHandorf, Richard N. Youngworth,
... OTE), (2) the Integrated Science Instrument Module Element (ISIM), and (3) the Spacecraft Element. The ISIM element consists of a composite bench structure that ... the three science instruments and the guider. The ISIM is also kinematically mounted to the telescope primary mirror structure. An enclosure surrounds the ISIM structure, isolates the ISIM region thermally from the other thermal regions of ... instruments and guider. Cryogenic optical testing of the ISIM Structure and the Science Instruments will be conducted ...
Tópico(s): Stellar, planetary, and galactic studies
2008 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Maria Nowak, Paul Cleveland, Emmanuel Cofie, J. Allen Crane, Pamela S. Davila, Bente Eegholm, Randolph P. Hammond, James B. Heaney, Jason E. Hylan, John D. Johnston, Raymond G. Ohl, Joseph Orndorff, Dean Osgood, Kevin Redman, Henry P. Sampler, Stephen A. Smee, Joseph M. Stock, Felix Threat, Robert A. Woodruff, Philip J. Young,
... Telescope Element and the Integrated Science Instrument Module (ISIM) element that contains four science instruments (SI) including a Guider. The alignment philosophy of ISIM is such that the cryogenic changes in the ... of the SI interfaces are captured in the ISIM alignment error budget. The SIs are aligned to ... conditions using laser tracker and theodolite metrology. The ISIM structure is thermally cycled and temperature-induced structural ... ensure they are within requirements. We compare the ISIM photogrammetry system performance to the ISIM metrology requirements ...
Tópico(s): Astronomical Observations and Instrumentation
2010 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
... develops a new integrated design method, known as iSIM (integrated Service Innovation Method), for simultaneous service innovation ... research method, the article theoretically defines and integrates iSIM's seven constitutive design process-elements: service strategy, ... end aligned integrated design method. It explains how iSIM would be holistically and iteratively practiced by practitioners, ... Amazon case studies using secondary data. Perspectives on iSIM from selected practitioners are discussed which confirm iSIM' ...
Tópico(s): Innovation and Knowledge Management
2015 - Springer Science+Business Media | Information Systems Frontiers
Takaaki Oba, Ryutaro Kajihara, Toshihiro Yokoi, Elizabeth A. Repasky, Fumito Ito,
... were treated with a combinatorial in situ immunomodulation (ISIM) regimen comprised of intratumoral administration of Flt3L, local ... TLR3/CD40 stimulations, followed by surgical resection. Neoadjuvant ISIM (neo-ISIM) generated tumor-specific CD8+ T cells that infiltrated ... resection of primary tumors. The efficacy of neo-ISIM was dependent on de novo adaptive T-cell ... early surgical resection after the completion of neo-ISIM. Importantly, neo-ISIM synergized with programmed cell death protein-1 ligand- ... lymph nodes abrogated the antimetastatic efficacy of neo-ISIM. Our findings illustrate the therapeutic potential of neoadjuvant ...
Tópico(s): Cancer Cells and Metastasis
2021 - American Association for Cancer Research | Cancer Research
Alice S. Ryan, Richard F. Macko, Matthew N. Peters, Frederick M. Ivey, Steven J. Prior, Lyndon Joseph, Charlene E. Hafer‐Macko,
... for IR (HOMA-IR) and insulin sensitivity index (ISIM). Results Adiponectin levels were positively associated with age ( ... 0.39; HOMA-IR: r = –0.45; and ISIM: r = 0.44, all P < .01) in stroke ... P < .05). HOMA-IR was 78% higher and ISIM was 81% lower in stroke survivors than control ... for IR (HOMA-IR) and insulin sensitivity index (ISIM). Adiponectin levels were positively associated with age (r = ... 0.39; HOMA-IR: r = –0.45; and ISIM: r = 0.44, all P < .01) in stroke ... P < .05). HOMA-IR was 78% higher and ISIM was 81% lower in stroke survivors than control ...
Tópico(s): Lipid metabolism and disorders
2009 - Elsevier BV | Journal of Stroke and Cerebrovascular Diseases
Maria Nowak, Paul Cleveland, Allen Crane, Pamela S. Davila, Acey Herrera, Jason E. Hylan, Andrew D. Liehr, J. G. Marsh, Raymond G. Ohl, Kevin Redman, Henry P. Sampler, Joseph M. Stock, Greg Wenzel, Robert A. Woodruff, Philip J. Young,
... Webb Space Telescope (JWST) Integrated Science Instrument Module (ISIM) is such that the cryogenic changes in the ... conditions using laser tracker and theodolite metrology. The ISIM structure is thermally cycled and temperature-induced mechanical ... within the predicted boundaries. We report on the ISIM photogrammetry system and its role in the cryogenic verification of the ISIM structure. We describe the cryogenic metrology error budget ... analysis and testing that was performed on the ISIM mockup, a full scale aluminum model of the ...
Tópico(s): Astronomy and Astrophysical Research
2008 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Andreas Vitalis, Nathan Baker, J. Andrew McCammon,
... this work we present a new software package (ISIM), which represents a flexible, computational tool for simulations ... both the solute and the mobile counterions. The ISIM software differs from previous schemes mainly by treating ... excess chemical potentials and bulk ion concentrations. Additionally, ISIM leverages the APBS software package to provide accurate ... through the efficient solution of Poisson's equation. ISIM has been validated on a variety of test ...
Tópico(s): Protein Structure and Dynamics
2003 - Taylor & Francis | Molecular Simulation
Brent J. Bos, David A. Kubalak, Scott Antonille, Raymond G. Ohl, John G. Hagopian, Pamela S. Davila, Joseph Sullivan, Michael Sánchez, Derek Sabatke, Robert A. Woodruff, Maurice te Plate, Clinton Evans, Victor Isbrucker, Stephen F. Somerstein, Martyn Wells, Samuel Ronayette,
... element (OTE) and the integrated science instrument module (ISIM). The ISIM Element primarily consists of a mechanical metering structure, ... exit pupil with the entrance pupils of the ISIM instruments. To verify that the ISIM Element will be properly aligned with the nominal ... degrees-of-freedom during optical testing of the ISIM Element. The pupil measurement scheme makes use of: ...
Tópico(s): Astronomical Observations and Instrumentation
2008 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Qingju Jiao, Yan Huang, Hong‐Bin Shen,
... further to define a new similarity metric (named ISIM) between two nodes. In contrast to the existing similarities, ISIM does not work directly on the observed data, ... in a convergent stable space. This feature makes ISIM robust to the observed noisy data in real-world networks. ISIM not only measures node's distance, but also ... on synthetic and real-world networks demonstrate that ISIM can be successfully applied to community detection in ...
Tópico(s): Opinion Dynamics and Social Influence
2015 - Elsevier BV | Physica A Statistical Mechanics and its Applications
Randy A. Kimble, M. Begoña Vila, Julie M. Van Campen, Stephan M. Birkmann, Brian Comber, Curtis Fatig, Alistair Glasse, Stuart D. Glazer, Douglas Kelly, Steven D. Mann, A. R. Martel, Kevin J. Novo-Gradac, Ray Ohl, Konstantin Penanen, Scott Rohrbach, Joseph Sullivan, Dean Zak, Julia Zhou,
... carried out for the Integrated Science Instrument Module (ISIM) of the James Webb Space Telescope (JWST). This ... final cryo-certification and calibration test of the ISIM, after its ambient environmental test program (vibration, acoustics, ... the-clock test program, the full complement of ISIM flight instruments, structure, harness radiator, and electronics were ... health and excellent performance of the instruments and ISIM systems, proving the ISIM element's readiness for integration with the telescope. ...
Tópico(s): Astronomy and Astrophysical Research
2016 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Mauricio Farez, Jorge Correale, Melissa J. Armstrong, Alexander Rae‐Grant, David Gloss, Diane Donley, Yolanda Holler‐Managan, Norman J. Kachuck, Douglas Jeffery, Maureen Beilman, Gary Gronseth, David Michelson, Erin Lee, Julie A. Cox, Tom Getchius, James J. Sejvar, Pushpa Narayanaswami,
... about infection risks associated with specific immunosuppressive/immunomodulating (ISIM) medications and treatment-specific vaccination guidance according to ... at least 4-6 weeks before initiating patients' ISIM therapy. Clinicians must screen for infections according to PI before initiating ISIM medications (Level A) and should treat patients testing ... clinicians must screen for latent infections before starting ISIM therapy even when not specifically mentioned in PI ( ... live-attenuated vaccines in people with MS receiving ISIM therapies. Clinicians should delay vaccinating people with MS ...
Tópico(s): Bacterial Infections and Vaccines
2019 - Lippincott Williams & Wilkins | Neurology
... Element (OTE) and the Integrated Science Instrument Module (ISIM) element that contains four science instruments (SI) including ... SI and Guider units are integrated to the ISIM structure and optically tested at NASA Goddard Space ... using optomechanical metrology. OSIM is aligned to the ISIM mechanical coordinate system at the cryogenic operating temperature ... cryogenic optical alignment, test and verification plan for ISIM.
Tópico(s): Calibration and Measurement Techniques
2009 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
... Authorizing Islam in Europe Frank Peter, Frank Peter ISIM, Leiden, The Netherlands Freie Universität Berlin, GermanySearch for more papers by this authorElena Arigita, Elena Arigita ISIM, Leiden, The Netherlands University of Granada, SpainSearch for ... papers by this author Frank Peter, Frank Peter ISIM, Leiden, The Netherlands Freie Universität Berlin, GermanySearch for more papers by this authorElena Arigita, Elena Arigita ISIM, Leiden, The Netherlands University of Granada, SpainSearch for ...
Tópico(s): Gender and Women's Rights
2006 - Wiley | The Muslim World
Cengiz Kunt, John D. Johnston, Andrew Bartoszyk, Steve Hendricks,
The JWST Integrated Science Instrument Module (ISIM) includes a large metering structure (approx. 2m × 2m × 1.5m) that houses the science instruments and guider. Stringent dimensional stability and repeatability ... proven challenging. In response to the challenge, the ISIM structure team considered literally over 100 primary structure ... this paper, we review the evolution of the ISIM primary structure topology and kinematic mount configuration to ...
Tópico(s): Spacecraft and Cryogenic Technologies
2006 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
... the Study of Islam in the Modern World (ISIM) and ISIM Chair at Leiden University, The Netherlands.Search for ... the Study of Islam in the Modern World (ISIM) and ISIM Chair at Leiden University, The Netherlands.Search for ...
Tópico(s): International Development and Aid
2005 - Wiley | Development and Change
Alistair Curd, Alexa Cleasby, Katarzyna Makowska, Andrew G. York, Hari Shroff, Michelle Peckham,
... in live cells. The "instant structured illumination microscope" (iSIM) is a system designed for this purpose. Similarly to standard structured illumination microscopy (SIM), an iSIM provides a twofold improvement over widefield microscopy, in ... of super-resolution images. The assembly of an iSIM is reasonably complex, involving the combination and alignment ... and provide instructions for, the construction of an iSIM, including minor modifications to a previous design in ...
Tópico(s): Optical Coherence Tomography Applications
2015 - Elsevier BV | Methods
Renee Gracey, Andrew Bartoszyk, Emmanuel Cofie, Brian Comber, G. Hartig, Joseph Howard, Derek Sabatke, Greg Wenzel, Raymond G. Ohl,
... Space Telescope includes the Integrated Science Instrument Module (ISIM) element that contains four science instruments (SI) including ... STOP) modeling in support of all phases of ISIM development. In this paper, we focus on modeling and results associated with test and verification. ISIM's test program is bound by ground environments, ... This paper describes STOP modeling used to predict ISIM system performance in 0g and at various on- ...
Tópico(s): Calibration and Measurement Techniques
2016 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Xiaohua Wang, Feng Xu, Ming Cheng, Xing Wang, Dongmei Zhang, Lihua Zhao, Hong-Li Cai, Haiyan Huang, Tong Chen, Xiulin Zhang, Xueqin Wang, Xingbo Cheng, Jianbin Su, Yan Lu,
... using C-peptide, i.e., ISHOMA-cp and ISIM-cp, respectively. Islet β-cell function was assessed ... assess postchallenge glucagon. The results showed ISHOMA-cp, ISIM-cp and ISSI2cp decreased, while AUCgla notably increased, ... S-TBAs were inversely correlated with ISHOMA-cp, ISIM-cp and ISSI2cp (r = –0.21, –0.15 ... 0.04, t = –2.82, p = 0.005), ISIM-cp (β = –0.11, t = –7.05, p < ...
Tópico(s): Pancreatic function and diabetes
2020 - Japan Endocrine Society | Endocrine Journal
Aicha Idriss Hentati, Lamia Chaari Fourati, Essia Elgharbi, Sana Tayeb,
... Computer Science and Multimedia Higher Institute of Sfax (ISIMS), Tunisia. Her research activities are related to digital ... Institute of Computer Science and Multimedia of Sfax (ISIMS), Tunisia. She got her diploma in computer technologies ... Institute of Computer Science and Multimedia of Sfax (ISIMS), Tunisia. She got her diploma in information technologies in 2020 from ISIMS.
Tópico(s): Robotic Path Planning Algorithms
2022 - Taylor & Francis | International Journal of Modelling and Simulation
Elie Bellevrat, Ph. Menanteau,
... model for the global energy system modeling and ISIM model for the steel sector based prospective (Hidalgo, ... in ULCOS Phase 1 have been introduced into ISIM as generic technologies. ISIM was then integrated as a module into POLES ...
Tópico(s): Global Energy and Sustainability Research
2009 - Dunod | Revue de Métallurgie
... Apple-Macintosh. Comparison is made for three languages: ISIM and ACSL for the IBM-PC and STELLA for the Macintosh. For ISIM and ACSL model equations have to be set ... be in a tabular or graphic form. With ISIM interactive variation of parameters (pump on/off; stirrer ...
Tópico(s): Hydrology and Watershed Management Studies
1991 - Elsevier BV | Agriculture Ecosystems & Environment
Joe Sullivan, Bill Eichhorn, Rob von Handorf, Derek Sabatke, Nick Barr, Rich Nyquist, Bob Pederson, Rick Bennnett, Paul Volmer, Dave Happs, Adrian F. Nagle, Rick Ortiz, Tony Kouri, Paul Hauser, Jon Seerveld, Dave Kubalak, Brad Greeley, Claef Hakun, Doug Leviton, Qian Gong, Pam Davila, Ray Ohl, Jeff Kirk, Clint Davis, Jenny Chu, Erin Wilson, Bill Chang, S. D. Mann, Robert Rashford, Corbett Smith,
... testing of the JWST Integrated Science Instrument Module (ISIM). OSIM is currently being assembled at the Goddard ... the OSIM during the optical test program of ISIM and the Science Instruments. Where applicable, the ISIM tests are also described.
Tópico(s): Calibration and Measurement Techniques
2010 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Luís Miranda, J. Rio, João Miranda Guedes, Anı́bal Costa,
... studied using an acoustic Indirect Sonic Impact Method, ISIM. The test campaign included direct and indirect wave ... as well as of wall panels. Using the ISIM technique it was possible to obtain two types ... panels were also used and compared with the ISIM results.
Tópico(s): Seismic Waves and Analysis
2012 - Elsevier BV | Construction and Building Materials
Andrew Bartoszyk, John D. Johnston, Charles Kaprielian, Jonathan L. Kuhn, Cengiz Kunt, Benjamin Rodini, Daniel Young,
... major design and analysis challenge for the JWST ISIM structure is thermal survivability of metal/composite adhesively ... To gain confidence in analyzing and designing the ISIM joints, a comprehensive joint development test program has ...
Tópico(s): High-Velocity Impact and Material Behavior
2005 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
... in the Context of Globalization: European Muslim Youth', ISIM, March 1999, p. 25. Interview with young Muslim ... Soluble into Germany? Sunni Muslims of Turkish Origin', ISIM, December 1999, p. 30. The concept of reversion ... Digital Islam: Changing the Boundaries of Religious Knowledge?' ISIM, March 1999, pp. 1, 23. To give an ...
Tópico(s): Religious Education and Schools
2004 - Taylor & Francis | Journal of Muslim Minority Affairs
Ken C. Chiu, Lee‐Ming Chuang, Carol Yoon, Mohammad F. Saad,
... insulin sensitivity (ISIH) and total body insulin sensitivity (ISIM) were estimated from the oral glucose tolerance test. ... a lower ISIH (p=0.002), a lower ISIM (p=0.009), a higher %B (p=0. ... polymorphism was a weak, but independent determinant for ISIM (p=0.089) and %B (p=0.083). ...
Tópico(s): Metabolism, Diabetes, and Cancer
2000 - BioMed Central | BMC Genomic Data
Stephan M. Birkmann, Pierre Ferruit, Catarina Alves de Oliveira, Torsten Böker, Guido De Marchi, Giovanna Giardino, M. Sirianni, M. Stuhlinger, Peter Jensen, Peter Rumler, Massimo Falcolini, Maurice B. J. te Plate, G. Cresci, Bernhard Dorner, Ralf Ehrenwinkler, Xavier Gnata, Thomas Wettemann,
... for integration into the Integrated Science Instrument Module (ISIM). We highlight the major results from the instrument ... ongoing preparations for the Integrated Science Instrument Module (ISIM) test campaign to begin in June 2014, and ... detector and micro-shutter assemblies following the first ISIM test cycle.
Tópico(s): Astrophysics and Star Formation Studies
2014 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Yan Bi, Guobang Tong, Haiyan Yang, Mengyin Cai, Juan Manuel Malacara, Jun Liang, Xin Bin, Haijun Miao, Zhaokang Peng, Dalong Zhu,
... min (InsAUC30 /GluAUC30 )] and insulin sensitivity [Matsuda index (ISIM )] were assessed during the standard meal tolerance test ... 25 kg/m(2) ) subgroup, the increase in ISIM was not significant, but the improvement in InsAUC30 / ... in HbA1c (r = -0.374, p = 0.000), ISIM (r = 0.356, p = 0.001), and ΔGLP- ...
Tópico(s): Pancreatic function and diabetes
2013 - Wiley | Diabetes/Metabolism Research and Reviews