Takashi Ichiyama, Shoichi Endo, Michiya Kaneko, Hiroshi Isumi, Tomoyo Matsubara, Susumu Furukawa,
... Yamaguchi, JapanSearch for more papers by this authorHiroshi Isumi, Hiroshi Isumi Department of Pediatrics, Yamaguchi University School of Medicine ... Yamaguchi, JapanSearch for more papers by this authorHiroshi Isumi, Hiroshi Isumi Department of Pediatrics, Yamaguchi University School of Medicine ...
Tópico(s): Viral Infections and Immunology Research
2003 - Wiley | Pediatrics International
S. Kapas, Paula M. Farthing, Maria Luisa Tenchini,
... from cultured vascular smooth muscle and endothelial cells (Isumi et al., 1998Isumi Y. Shoji H. Sugo S. ... and LPS may act synergistically when added simultaneously (Isumi et al., 1998Isumi Y. Shoji H. Sugo S. ... about six times less than vascular endothelial cells (Isumi et al., 1998Isumi Y. Shoji H. Sugo S. ... studies using primary cultures of rat endothelial cells (Isumi et al., 1998Isumi Y. Shoji H. Sugo S. ... bbrc.1994.2229Crossref PubMed Scopus (192) Google Scholar;Isumi et al., 1998Isumi Y. Shoji H. Sugo S. ...
Tópico(s): Immune Response and Inflammation
2001 - Elsevier BV | Journal of Investigative Dermatology
Takashi Hayashi, Takashi Ichiyama, Miki Nishikawa, Hiroshi Isumi, Susumu Furukawa,
... Yamaguchi, JapanSearch for more papers by this authorHiroshi Isumi, Hiroshi Isumi Department of Pediatrics, Yamaguchi University School of Medicine, ... Yamaguchi, JapanSearch for more papers by this authorHiroshi Isumi, Hiroshi Isumi Department of Pediatrics, Yamaguchi University School of Medicine, ...
Tópico(s): Autism Spectrum Disorder Research
1998 - Wiley | Annals of Neurology
Tamotsu Kusano, Takehito Ueda, Hikaru Nakagawa,
... and 63.1 and 65.3 mm at Isumi in Chiba prefecture, respectively. The differences in SVL ... the Habu population (eight years) than in the Isumi population (five years), and the age at first ... sexes in both populations except for males at Isumi (three years). In the latter, age at first ...
Tópico(s): Fish Ecology and Management Studies
2006 - | Current Herpetology
Tetsuya Sakai, Osamu Fujiwara, Takanobu Kamataki,
The burial history of the Isumi River lowland was reconstructed based on a facies analysis of borehole and geoslicer samples, undisturbed sediment samples collected by 4.0- ...
Tópico(s): earthquake and tectonic studies
2005 - Elsevier BV | Sedimentary Geology
Nemer Samniah, Scott Sakaguchi, Keith G. Lurie, Demosthenes Iskos, David G. Benditt,
... Yamaguchi T. Igarashi Y. Tamura Y. Yamazoe M. Isumi T. Shibata A. Tanaka Y. Watanabe K. A ... Yamaguchi T. Igarashi Y. Tamura Y. Yamazoe M. Isumi T. Shibata A. Tanaka Y. Watanabe K. A ...
Tópico(s): Heart Rate Variability and Autonomic Control
2001 - Elsevier BV | The American Journal of Cardiology
Takaaki Tanaka, Hajime Kamiya, Kazutoyo Asada, Shigeru Suga, Masaru Ido, Masakazu Umemoto, Kazunobu Ouchi, Hiroaki Ito, Haruo Kuroki, Takashi Nakano, Koki Taniguchi,
... City, Mie Prefecture; Kurashiki City, Okayama Prefecture; and Isumi City, Chiba Prefecture. RV genotypes were determined using ... 8] and the emergence of G2P[4]. In Isumi City, G1P[8] was dominant (70.3%) before ...
Tópico(s): Animal Virus Infections Studies
2017 - National Institute of Infectious Diseases | Japanese Journal of Infectious Diseases
Yutaka Ueda, Asami Yagi, Hazuki Abe, Satoshi Nakagawa, Ryoko Minekawa, Haruo Kuroki, Ayako Miwa, Tadashi Kimura,
... the national government’s recommendation, one local government Isumi City started sending a leaflet containing information of ... their parents in a way similar to what Isumi City has now shown to be effective.
Tópico(s): Hepatitis B Virus Studies
2020 - Nature Portfolio | Scientific Reports
Gary S. Becker, H. Gregg Lewis,
... 3-319-57365-6_314-1Yukako Tani, Aya Isumi, Satomi Doi, Takeo Fujiwara Number of Siblings and ...
Tópico(s): Demographic Trends and Gender Preferences
1973 - University of Chicago Press | Journal of Political Economy
Tópico(s): Botanical Research and Chemistry
1984 - Wiley | Plant Cell & Environment
Masanori Isumi, Noriaki Nomura, Takao Shibuya,
To have a national methodology for pre-earthquake planning, a model for predicting the post-earthquake behavior of city lifeline systems was developed. We discussed three factors in the model: structural damage, functional damage, and the restoration process after the earthquake. The restoration process is basically described by a differential equation applicable to a service area represented by a census mesh, and is applied to the lifelines (i.e., supply systems of gas, electric power, and water) ...
Tópico(s): Seismic Performance and Analysis
1985 - SAGE Publishing | International Journal of Mass Emergencies & Disasters
Yoshikuni Ohta, Hitoshi Okuda, Fumihiko Suwa, Shigenori OKADA, Isumi Toda,
This paper examines the application of the acryl plastic injection to the preparation of vascular corrosion microcasts for scanning electron microscopy (SEM). The original injection method using acryl plastic was described by Taniguchi, Ohta et al. in 1952 and 1955, under the title of "New improved method for injection of acrylic resin". Three dimensional observations were undertaken in our laboratory on the angiology at the macro- and microscopic levels of various organs from various mammals employing ...
Tópico(s): Dental materials and restorations
1990 - Keiji Okajima | Okajimas Folia Anatomica Japonica
Tópico(s): Leaf Properties and Growth Measurement
1987 - Wiley | Plant Cell & Environment
Akimichi Takemura, Mamoru Uemura, Isumi Toda, Gang Fang, Masaya Hikida, Fumihiko Suwa,
We used four ferrets (Mustela putorius furo) and observed these animals dorsal tongue surface morphology via scanning electron microscope and light microscope. In this investigation, we focused on the food habits and discussed the morphology of the lingual papillae from the viewpoint of comparative anatomy. The ferret has conically-shaped filiform papillae in the posterior, middle and anterior region of the tongue body, and circular-distributed filiform papillae in the lingual apex region. The ferret ...
Tópico(s): Veterinary Equine Medical Research
2009 - Keiji Okajima | Okajimas Folia Anatomica Japonica
... carnivore species living sympatrically in the area of Isumi City, southeastern Chiba Prefecture, central Japan, was analyzed ...
Tópico(s): Animal Behavior and Welfare Studies
2009 - | Mammal Study
Masakazu Mimaki, Hideyuki Hatakeyama, Takashi Ichiyama, Hiroshi Isumi, Susumu Furukawa, Manami Akasaka, Atsushi Kamei, Hirofumi Komaki, Ichizo Nishino, Ikuya Nonaka, Yu‐ichi Goto,
Two novel mitochondrial DNA base changes were identified at both sides of the 3243A > G mutation, the most common mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). One was a 3244G > A transition in a girl with MELAS. The other was a 3242G > A transition in a girl with a mitochondrial disorder without a MELAS phenotype. Although the two base changes were adjacent to the 3243A > G mutation, they had different effects on the clinical phenotype, ...
Tópico(s): ATP Synthase and ATPases Research
2009 - Elsevier BV | Mitochondrion
Takashi Ichiyama, Hiroshi Isumi, Tomomi Yoshitomi, Miki Nishikawa, Tomoyo Matsubara, Susumu Furukawa,
We examined whether or not NF-kappaB, a factor that regulates expression of the genes that code for pro-inflammatory cytokines, is activated in cerebrospinal fluid (CSF) cells to investigate the production of pro-inflammatory cytokines by CSF cells in patients with meningitis. Western blotting demonstrated that NF-kappaB was more activated in CSF cells of patients with bacterial meningitis than in those of patients with aseptic meningitis. NF-kappaB was hardly activated in carcinomatous meningitis. ...
Tópico(s): Inflammasome and immune disorders
2002 - Taylor & Francis | Neurological Research
Toshihiro Tsuruda, John C. Burnett,
... Clin Invest. 1994; 94: 2158–2561.CrossrefMedlineGoogle Scholar7 Isumi Y, Shoji H, Sugo S, Tochimoto T, Yoshioka ...
Tópico(s): Hormonal Regulation and Hypertension
2002 - Lippincott Williams & Wilkins | Circulation Research
Naoto Minamino, Katsuro Kikumoto, Yoshitaka Isumi,
Adrenomedullin (AM) was originally identified in the extracts of human pheochromocytoma tissue, but this peptide is now known to be synthesized and secreted from many kinds of cells in the body, including vascular smooth muscle cells, endothelial cells, fibroblasts, cardiac myocytes, epithelial cells, and cancer cells. In this review, we summarize AM-secreting and AM gene-expressing cells in addition to the regulation of secretion and gene expression of AM. Although the data are still limited to ...
Tópico(s): Cancer, Stress, Anesthesia, and Immune Response
2002 - Wiley | Microscopy Research and Technique
Takashi Ichiyama, Hiroshi Isumi, Hiroshi Ozawa, Tomoyo Matsubara, Tsuneo Morishima, Susumu Furukawa,
AbstractThis study determined the concentrations of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), soluble TNF receptor 1 (sTNFR1) and soluble E-selectin (sE-selectin) in cerebrospinal fluid (CSF) and serum from 15 children with influenza virus-associated encephalopathy to determine the role of cytokines in the pathogenesis. Cytokines and sTNFR1 were measured by enzyme-linked immunosorbent assay. The CSF IL-6, TNF-α and sTNFR1 concentrations were elevated in 9, 4 and 4 of 12 children, respectively. ...
Tópico(s): Bacterial Infections and Vaccines
2003 - Informa | Scandinavian Journal of Infectious Diseases
Keiichi Hasegawa, Takashi Ichiyama, Hiroshi Isumi, Masanobu Nakata, Masakatu Sase, Susumu Furukawa,
Neonatal asphyxia results in hypoxic-ischaemic encephalopathy. Previous studies have demonstrated that brain hypoxia and ischaemia lead to the production of proinflammatory cytokines, including tumour necrosis factor-alpha (TNF-alpha), interleukin-1 (IL-1) and IL-6. Transcription factor NF-kappaB is essential for the expression of these cytokines. We examined whether or not NF-kappaB is activated in peripheral mononuclear cells (PBMC) in neonatal asphyxia by flow cytometry. In addition, we examined ...
Tópico(s): NF-κB Signaling Pathways
2003 - Oxford University Press | Clinical & Experimental Immunology
Joji Okazaki, Yutaka Komasa, Daigo Sakai, Aiko Kamada, Takashi Ikeo, Isumi Toda, Fumihiko Suwa, Masahiro Inoue, Takanori Etoh,
The aim of this study was to biomechanically evaluate the primary stability of pure titanium orthodontic mini-implants, inserted into pre-drilled cavities of differing diameters. Mini-implants (1.2 mm diameter) were placed into 1.0 mm and 1.2 mm diameter cavities prepared in the mid-region of the bilateral hind leg femurs of anesthetized beagles. Removal torque strengths were measured immediately, 1, 3, 6, 9 and 12 weeks post-insertion of the implant. For mini-implants placed into 1-mm cavities, ...
Tópico(s): Dental Radiography and Imaging
2008 - Elsevier BV | International Journal of Oral and Maxillofacial Surgery
Mitsuhiro Kamiyoshihara, Toshiteru Nagashima, Takashi Ibe, Isumi Takeyoshi,
Cross-clamping the main pulmonary artery (PA) is a risky, stressful procedure for the general thoracic surgeon performing video-assisted thoracic major pulmonary resection (VATS). However, converting VATS to thoracotomy each time PA clamping is planned is a poor tactic. We present a simpler technique for VATS than the traditional method involving a thoracotomy. In VATS, DeBakey vascular clamps with double angle jaws are inserted through 1-cm access incisions. We clamped the main PA so as to maintain ...
Tópico(s): Pleural and Pulmonary Diseases
2010 - Oxford University Press | Interactive Cardiovascular and Thoracic Surgery
Mitsuhiro Kamiyoshihara, Toshiteru Nagashima, Takashi Ibe, Jun Atsumi, Kimihiro Shimizu, Isumi Takeyoshi,
Most studies have shown that thoracic epidural analgesia reduces postoperative pain, but it carries potential risks. Recently, video-assisted thoracoscopic surgery has become an established technique that causes minimal postoperative pain. This report shows that thoracic epidural analgesia is not always necessary after video-assisted thoracoscopic lobectomy. From January to December 2007, 30 consecutive patients who underwent video-assisted thoracoscopic lobectomy were examined retrospectively. ...
Tópico(s): Nausea and vomiting management
2010 - SAGE Publishing | Asian Cardiovascular and Thoracic Annals
Robin S. Matoza, Alexis Le Pichon, Julien Vergoz, P. Herry, Jean‐Marie Lalande, Hee‐Il Lee, Il‐Young Che, Alexander Rybin,
... 1690 km, Ussuriysk, Russia), and IS30 (1774 km, Isumi, Japan) represent a detailed record of the explosion ...
Tópico(s): Seismic Waves and Analysis
2010 - Elsevier BV | Journal of Volcanology and Geothermal Research
Elena González‐Rey, Alejo Chorny, Francisco O’Valle, Mario Delgado,
... Scopus (160) Google Scholar, 8Kubo A Minamino N Isumi Y Katafuchi T Kangawa K Dohi K Matsuo ...
Tópico(s): Immunotherapy and Immune Responses
2007 - Elsevier BV | American Journal Of Pathology
Takashi Ichiyama, Naoko Suenaga, Madoka Kajimoto, Jun Tohyama, Hiroshi Isumi, Masaya Kubota, Masato Mori, Susumu Furukawa,
It is well known that an acute encephalopathy occasionally follows prolonged febrile seizures. We measured the concentrations of interferon-γ, tumor necrosis factor-α (TNF-α), interleukin-2 (IL-2), IL-4, IL-6, IL-10, and soluble TNF receptor 1 (sTNFR1) in serum and CSF during the acute stage in 13 children with acute encephalopathy following prolonged febrile seizures (AEPFS) and 23 with prolonged febrile seizures without encephalopathy (PFS) to investigate the pathogenesis of AEPFS. Serum IL-6, IL-10, ...
Tópico(s): Epilepsy research and treatment
2007 - Elsevier BV | Brain and Development
Produção Nacional
Revisado por pares
Cláudia Maria Gaspardo, Cátia Isumi Miyase, Juliana Thomazatti Chimello, Francisco Eulógio Martinez, Maria Beatriz Martins Linhares,
The aim of the present study was to examine the efficacy and potential side effects of repeated doses of oral sucrose for pain relief during procedures in NICU. Thirty-three preterm neonates were randomly allocated in blind fashion into two groups, the sucrose group (SG=17) and the control group (CG=16). The responses of neonates to pain and distress were assessed during blood collection on four consecutive assessment (ass.) days. For the first assessment, the neonates did not receive any solution ...
Tópico(s): Infant Health and Development
2007 - Lippincott Williams & Wilkins | Pain
Naoko Suenaga, Takashi Ichiyama, Masaya Kubota, Hiroshi Isumi, Jun Tohyama, Susumu Furukawa,
Prolonged febrile seizures may be followed by acute encephalopathy with neurological sequelae. To investigate the function of the blood-brain-barrier (BBB) in acute encephalopathy following prolonged febrile seizures with neurological sequelae (AEPFS), the concentrations of serum matrix metalloproteinase-9 (MMP-9) and tissue inhibitors of metalloproteinases 1 (TIMP-1) were measured by ELISA in 10 children with AEPFS, 16 with prolonged febrile seizures without encephalopathy (PFS), 20 with simple febrile ...
Tópico(s): Mosquito-borne diseases and control
2007 - Elsevier BV | Journal of the Neurological Sciences
Yoshitaka Isumi, Tsuyoshi Hirata, Hiroshi Saitoh, Tomoya Miyakawa, Kenji Murakami, Gen Kudoh, Hirofumi Doi, Kohtaro Ishibashi, Hiroto Nakajima,
We found a novel protein–protein interaction between ubiquitin-specific protease 15 (USP15) and skeletal muscle LIM protein 1 (SLIM1): USP15 and SLIM1 directly bound under cell-free conditions and co-immunoprecipitated from the lysates of the cells, where they were co-expressed; and USP15 deubiquitinated SLIM1, resulting in the increase of protein levels of SLIM1. Because SLIM1 is strongly implicated in the pathogenesis of myopathies and cardiomyopathies, we generated transgenic (TG) mice with cardiac- ...
Tópico(s): RNA modifications and cancer
2011 - Elsevier BV | Biochemical and Biophysical Research Communications