John Huxley, Askold krushelnycky, Christina Hardyment, lola Smith, Anthony Simonds-Gooding, Jane Langdon-Davies, John Jay City Editor, A Murray Wilson, Michelene Wandor, John Davison, Jon Swain, Rob Hughes, John Peter, D A Payne, Hazhir Teimourian, Mark Reason, Bemard Cafferty, Sir Jeffrey Sterling, Eric Dymock, Jill Hartley, Christopher Smallwood Economics Editor, John Jay, Christopher Somerville, Meriel McCOOEY, Danby Bloch, Nick Rufford, Sally Emerson, Neville Hodgkinson Medical Correspondent, Graham Rose, John Diamond, Norman Howell, Julia Brookes, Iain McKell, Robin Morgan, Sally Payne, Ian Williams Business Correspondent, Linda Taylor, Stephen Milligan, Peter Kimber, Gillian Hall, Jo Revill, Jason Tomas, Mark Hosenball, Edward Welsh, Denise Heywood, Keren David, Caroline St John-Brooks, Richard Eaton, Denise Winn, N F Simpson, Angela Long Editor, Judi Bevan Deputy City Editor, Patrick Stoddart, Randolph McGowan, Susan Marling, Kevin Mitchell, Alex Sutherland, Iain Johnstone, Robert Sandall, Lis Leigh, Frances Partridge, David Brierley, Irwin Stelzer, John Newell, Dr R J Crampton, Peter Godwin, Robert Hewison, George Turnbull, Deryk Brown, Mick Brown, David Dougill, Ivan Fallon, Dr D Shapland, Dick Leonard, Don Davies, Rebecca Tyrrel, John Mortimer, Mark Blacklock, Allan Massie, Philip Beresford Industrial Editor, John Witherow, Rosie Barne Social Democratic Party Mp for Greenwich, David Elstein, Egon Ronay, Drew, Susan Crosland, Julian Amery, Charlie Coutts, P A McKenna, Colin McCabe, Patrick Callan, Sue Mott, John Cassidy, Robin Marlar, Phillips, Charlotte Atkins, Margaret Thatcher, Mary Ewan, A J Ayer, Paul Golding, Brian Moynahan, Rachel Blunt, Paul Donovan, Juliet Herd, S Gury, Kate Etheridge, Paul Taylor, Jonathan Todd, Chris Nawral, Paul Driver, Sarah Miller Edited, M Hood, Sam McCluskie, Austin MacCurtain, David Leppard, Tim Rayment, Peter Freedman, Mazher Mahmood, Brian Jackman, Richard Girling, Marion Cotter, Elizabeth Grice, Mary Anne, John Hopkins, Nigel Bowden, Martin Jacques, Judi Bevan, Brian Walden, Maria Laura, Diana Broers, Gillian Upton, Diana Wright Editor, Gareth David, Simon Freeman, Stephen Pile, Stanley Levenson, Marie Colvin, Allen Levy Director, Craig Brown, Diana Wright, Christopher Smallwood, Malcolm W Browne, Lucy Pinney, Stephen Jones, Michel Syrett, Desmond Shawe-Taylor, Jonathan Dimbleby, Renée Sockett, Raymond Godfrey, Rob Ryan, Nick Rufford Science Correspondent, Jorn Ruby, Dilys Powell, Chris Jones, Brough Scott, John McEwen, Richard Woods, Angela Conner, Maurice Chittenden, Neil MacGregor Director, Dudley Doust, Ian Dunning, David Hughes Political Correspondent, Brian MacArthur, Jonathon Porritt, Richard Kirkland, Michael Jones Political Editor, Roger Clarke, Steve Tongue, William Boyd, Mihir Bose, Philip Beresford, Alan Long, Godfrey Smith, Jonathan Clark, Richard Burnell, Annabel Walker, Brian Glanville, Angus Roxburgh, Carmel McQuaid, Edward Pearce, Paul Radeliffe, J Enoch Powell, Nadine Meisner, Simon Jenkins, Sue Cameron, Jon Craig Home Affairs Correspondent, Godfrey Golzen, David Sinclair, L Barratt, Maureen Walker, John Morton General Secretary, David Wickers, Charlie Pye-Smith, Ian Williams, David Bellamy, Caroline McChie, Sanjiv Vedi Councillor, Valerie Grove, Glyn Arfon Davies, Margaret Park, Edmund White, J Holmes, Tony Hetherington, Jim Muir, Penelope Gillian, Joanna Simon, Christopher Sinclair-Stevenson Managing Director, Robert Kilroy-Silk, John Peter's, Boris Schapiro, Bill Jordan Chairman,
... Hudson £12.95 pp256 High rise of a basso profundo Chaliapin by Victor Borovsky Hamish Hamilton £25. ...
1988 - Gale Group | Sunday Times HA GDA
Rafael Basso, Balázs Kulcsár, Iván Sánchez-Díaz, Xiaobo Qu,
Dynamic routing of electric commercial vehicles can be a challenging problem since besides the uncertainty of energy consumption there are also random customer requests. This paper introduces the Dynamic Stochastic Electric Vehicle Routing Problem (DS-EVRP). A Safe Reinforcement Learning method is proposed for solving the problem. The objective is to minimize expected energy consumption in a safe way, which means also minimizing the risk of battery depletion while en route by planning charging whenever ...
Tópico(s): Vehicle Routing Optimization Methods
2021 - Elsevier BV | Transportation Research Part E Logistics and Transportation Review
Rafael Basso, Balázs Kulcsár, Ivan Sanchez-Diaz,
Routing electric commercial vehicles requires taking into account their limited driving range, which is affected by several uncertain factors such as traffic conditions. This paper presents the time-dependent Electric Vehicle Routing Problem with Chance-Constraints (EVRP-CC) and partial recharging. The routing method is divided into two stages, where the first finds the best paths and the second optimizes the routes. A probabilistic Bayesian machine learning approach is proposed for predicting the ...
Tópico(s): Transportation and Mobility Innovations
2021 - Elsevier BV | Transportation Research Part B Methodological
Ingrid Laurendeau, Marcela Ferrer, Delia Garrido, Nicky D’Haene, Patricia Ciavarelli, Armando Basso, Michel Vidaud, Ivan Bièche, Isabelle Salmon, Irene Szijan,
The Hedgehog (Hh) signaling pathway has an important role during embryogenesis and in adult life, regulating proliferation, angiogenesis, matrix remodeling and stem-cell renewal. Deregulation of the Hh pathway is involved in tumor development, since mutations in several components of this pathway were found in patients with basal cell carcinoma, medulloblastoma and other tumors; however, the role of Hh in meningiomas has not been studied yet. Meningiomas represent 30% of primary cranial tumors, are ...
Tópico(s): Teratomas and Epidermoid Cysts
2010 - BioMed Central | Molecular Medicine
Ingrid Laurendeau, Marcela Ferrer, Delia Garrido, Nicky D’Haene, Patricia Ciavarelli, Armando Basso, Michel Vidaud, Ivan Bièche, Isabelle Salmon, Irene Szijan,
ErbB family receptors mediate major cellular functions implied in tumorigenesis, though their role in meningiomas was not thoroughly studied. Meningiomas represent 30% of primary cranial tumors, are mostly benign, and prevail in the second half of life. Tumor therapy requires information about molecular alterations, thus we studied expression of ErbB receptor and ligand genes by real-time RT-PCR in different meningioma grades. Receptors were overexpressed (ErbB1, ErbB2) or underexpressed (ErbB3, ErbB4). ...
Tópico(s): Radiopharmaceutical Chemistry and Applications
2009 - Taylor & Francis | Cancer Investigation
Giovanna Gallina, Luigi Dolcetti, Paolo Serafini, Carmela De Santo, Ilaria Marigo, Mario P. Colombo, Giuseppe Basso, Frank Brombacher, Ivan Borrello, Paola Zanovello, Silvio Bicciato, Vincenzo Bronte,
Active suppression of tumor-specific T lymphocytes can limit the efficacy of immune surveillance and immunotherapy. While tumor-recruited CD11b+ myeloid cells are known mediators of tumor-associated immune dysfunction, the true nature of these suppressive cells and the fine biochemical pathways governing their immunosuppressive activity remain elusive. Here we describe a population of circulating CD11b+IL-4 receptor α+ (CD11b+IL-4Rα+), inflammatory-type monocytes that is elicited by growing tumors ...
Tópico(s): Immunotherapy and Immune Responses
2006 - American Society for Clinical Investigation | Journal of Clinical Investigation
Produção Nacional
Revisado por pares
Laura Mensch Pereira, José Antônio Gonzalez da Silva, Odenis Alessi, Natiane Carolina Ferrari Basso, Ivan Ricardo Carvalho, Márcia Sostmeyer Jung, Gerusa Massuquini Conceição, Juliana Aozane Da Rosa,
Purpose: The objective of the study is to identify oat cultivars with satisfactory productivity and adaptability to reduced use of fungicide concomitant with the longest interval between the last application and grain harvest, in the recommendation of biotype more adjusted to agroecological management. Method/design/approach: The study was developed in 2018, 2019, in Augusto Pestana, RS, Brazil. The experimental design was a randomized block with three replications in a 23 x 5 factorial, for 23 ...
Tópico(s): Crop Yield and Soil Fertility
2023 - CENTRO UNIVERSITARIO FEI | Revista de Gestão Social e Ambiental
Produção Nacional
Revisado por pares
Juliana Aozane Da Rosa, José Antônio Gonzalez da Silva, Raul Vicenzi, Ana Paula Cecatto, Angélica Reolon Costa, Cibele Luisa Peter, Natiane Carolina Ferrari Basso, Ivan Ricardo Carvalho, Francine Lautenchleger, Jaqueline Sgarbossa, Denize da Rosa Fraga, Willyan Júnior Adorian Bandeira,
The adjustment of buckwheat density and sowing time in an organic growing system guarantees satisfactory productivity with better environmental quality. The objective of the study is to adjust the sowing density and the best growing season of buckwheat, comparing the organic and conventional growing system. In the study, two experiments were conducted in 2017 and 2018. Experiment one, in a randomized block design with eight replications in a 4 x 2 factorial, for sowing density (40, 80, 120 and 160 ...
Tópico(s): Magnetic and Electromagnetic Effects
2022 - Southern Cross Publishing | Australian Journal of Crop Science
Abel Santos Carreira, María Queralt Salas, Mats Remberger, Igor Novitzky‐Basso, Arjun Law, Wilson Lam, Ivan Pašić, Dennis Kim, Fotios V. Michelis, Auro Viswabandya, Armin Gerbitz, Jeffrey H. Lipton, Shahid Husain, Rajat Kumar, Jonas Mattsson,
This study investigated the single-center incidence and risk factors for bloodstream infections (BSIs) in 651 adults who underwent allogeneic hematopoietic cell transplantation (alloHCT) between 2015 and 2019 and explored the impact of these BSIs on post-transplantation outcomes. Antibiotic prophylaxis with ciprofloxacin was given during the aplastic phase. Overall, the median patient age was 57 years, 79.7% of patients received an alternative donor graft, and 68.7% received post-transplantation cyclophosphamide ( ...
Tópico(s): Renal Transplantation Outcomes and Treatments
2021 - Elsevier BV | Transplantation and Cellular Therapy
Carmela Vennari, Paola Salvati, Cinzia Bianchi, D. Casarano, Mario Parise, Alessia Basso, Ivan Marchesini,
In many territories, geo-hydrological disasters represent a problem of considerable importance, given that they can cause substantial property damage, above all, life losses. In Italy, the geo-hydrological risk is widespread depending on the geomorphological settings, climate conditions and anthropic pressure. Accurate knowledge regarding the spatial and temporal extensions of past events, as well as the associated damages, allows the elaboration of hazard and risk maps. The resulting data are strongly ...
Tópico(s): Cryospheric studies and observations
2022 - Elsevier BV | Journal of Environmental Management
Produção Nacional
Revisado por pares
Dionei Schmidt Muraro, Claudir José Basso, Ivan Ricardo Carvalho, Vinícius Jardel Szareski, Luan Cutti, Adalin Cézar Moraes de Aguiar, Vanessa Alba da Silva, Marlo Adriano Bison Pinto, Francine Lautenchleger,
The objective of this study was to evaluate the behavior of brown linseed, submitted to different spacing between lines. The experiment was carried out at the Federal University of Santa Maria, Frederico Westphalen Campus, under a typical eutrophic Red Latosol, from September to December 2013. The experimental design was a randomized complete block design with four replications and four treatments, with experimental plots of 4.0 × 3.0 meters, totaling 12.0 m². The treatments consisted ...
Tópico(s): Soybean genetics and cultivation
2018 - Canadian Center of Science and Education | Journal of Agricultural Science
Stefania Crippa, Anastasia Conti, Valentina Vavassori, Samuele Ferrari, Stefano Beretta, Silvia Rivis, Roberto Bosotti, Serena Scala, Stefania Pirroni, Raisa Jofra-Hernandez, Ludovica Santi, Luca Basso‐Ricci, Ivan Merelli, Pietro Genovese, Alessandro Aiuti, Luigi Naldini, Raffaella Di Micco, Maria Ester Bernardo,
Mesenchymal stromal cells (MSCs) have been employed in vitro to support hematopoietic stem and progenitor cell (HSPC) expansion and in vivo to promote HSPC engraftment. Based on these studies, we developed an MSC-based co-culture system to optimize the transplantation outcome of clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 gene-edited (GE) human HSPCs. We show that bone marrow (BM)-MSCs produce several hematopoietic supportive and anti-inflammatory factors capable of alleviating ...
Tópico(s): Pluripotent Stem Cells Research
2022 - Elsevier BV | Molecular Therapy
Rafael Basso, Balázs Kulcsár, Bo Egardt, Peter Lindroth, Ivan Sanchez-Diaz,
When planning routes for fleets of electric commercial vehicles, it is necessary to precisely predict the energy required to drive and plan for charging whenever needed, in order to manage their driving range limitations. Although there are several energy estimation models available in the literature, so far integration with Vehicle Routing Problems has been limited and without demonstrated accuracy. This paper introduces the Two-stage Electric Vehicle Routing Problem (2sEVRP) that incorporates improved ...
Tópico(s): Vehicle Routing Optimization Methods
2019 - Elsevier BV | Transportation Research Part D Transport and Environment
F. Serrano-Flores, Juan Carlos Pérez‐Jiménez, Iván Alberto Méndez, Kim Bassos‐Hull, Matthew J. Ajemian,
In the southern Gulf of Mexico, the spotted eagle ray ( Aetobatus narinari ) is the second most frequently caught batoid in small-scale fisheries off Campeche. Ecological aspects of this ray are unknown in this region, hampering the understanding of the relationship between its distribution and prey availability in the fishing area. In order to study the feeding habits of this batoid and characterize its potential prey in the study area, stomachs and intestines of 154 specimens (68 females and 86 males) ...
Tópico(s): Fish Ecology and Management Studies
2018 - Cambridge University Press | Journal of the Marine Biological Association of the United Kingdom
Stefania Crippa, Anastasia Conti, Valentina Vavassori, Samuele Ferrari, Stefano Beretta, Silvia Rivis, Roberto Bosotti, Serena Scala, Stefania Pirroni, Raisa Jofra-Hernandez, Ludovica Santi, Luca Basso‐Ricci, Ivan Merelli, Pietro Genovese, Alessandro Aiuti, Luigi Naldini, Raffaella Di Micco, Maria Ester Bernardo,
RNA-seq (GSE168834) and BAR-Seq (GSE206900)."The authors apologize for the inconvenience, and this error has been corrected online.
Tópico(s): Biomedical Ethics and Regulation
2022 - Elsevier BV | Molecular Therapy
Igor Novitzky‐Basso, Mats Remberger, Carol Chen, Ivan Pašić, Wilson Lam, Arjun Law, Armin Gerbitz, Auro Viswabandya, Jeffrey H. Lipton, Dennis Dong Hwan Kim, Rajat Kumar, Jonas Mattsson, Fotios V. Michelis,
During 2020, the concurrent novel COVID-19 pandemic lead to widespread cryopreservation of allogeneic hematopoietic cell transplant grafts based on National Marrow Donor Program and European Society of Blood and Marrow Transplantation recommendations, in order to secure grafts before the start of conditioning chemotherapy. We sought to examine the impact of this change in practice on patient outcomes. We analyzed the outcomes of 483 patients who received hematopoietic stem cell transplantation (HSCT) ...
Tópico(s): Childhood Cancer Survivors' Quality of Life
2021 - Wiley | European Journal Of Haematology
Mariana Pinto Pereira, Mats Remberger, Carol Chen, Armin Gerbitz, Dennis Dong Hwan Kim, Rajat Kumar, Wilson Lam, Arjun Law, Jeffrey H. Lipton, Fotios V. Michelis, Igor Novitzky‐Basso, Auro Viswabandya, Jonas Mattsson, Ivan Pašić,
The choice between an older matched sibling donor (MSD) and a younger matched unrelated donor (MUD) in allogeneic hematopoietic cell transplantation (HCT) remains a subject of ongoing debate. In this single-center retrospective study of 377 patients who received peripheral blood stem cell (PBSC) transplants for acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS), we compared outcomes of 85 patients who received grafts from MSDs age >60 years and 292 patients who received grafts from MUDs age < ...
Tópico(s): Acute Lymphoblastic Leukemia research
2023 - Elsevier BV | Transplantation and Cellular Therapy
Marco Alessandrini, Andrea Viziano, Rossella Pistillo, Ivan Granito, Luigi Basso, Nicola Preziosi, Alessandro Micarelli,
The vestibular system has been found to affect energy homeostasis and body composition, due to its extensive connections to the brainstem and melanocortin nuclei involved in regulating the metabolism and feeding behavior. The aim of this study was to evaluate – by means of a wrist-worn physical activity tracker and bioelectrical impedance analysis (BIA) – the energy expenditure (EE) in resting (REE) and free-living conditions and movement behavior in a group of chronic unilateral vestibular hypofunction ( ...
Tópico(s): Hearing, Cochlea, Tinnitus, Genetics
2021 - Elsevier BV | Journal of Clinical Neuroscience
Brindusa Anghel, Henrique S. Basso, Olympia Bover, José María Casado, Laura Hospido, Mario Izquierdo, Iván Kataryniuk, Aitor Lacuesta, José Manuel Montero, Elena Vozmediano,
This paper analyses the level of inequality in Spain and how it evolved over the course of the past crisis and the early stages of the current recovery. To this end, it first introduces the various dimensions of wage, income, consumption and wealth inequality, and studies how they have developed. The analysis shows less wage dispersion in Spain than in other comparable economies, even after the crisis years, while the surge in unemployment during the period resulted in a high level of inequality ...
Tópico(s): Economic Theory and Policy
2018 - Springer Nature | SERIEs
Marcos Bavdaz, Eric Wille, Kotska Wallace, Brian Shortt, Sebastiaan Fransen, N. Rando, Maximilien J. Collon, Marcelo Ackermann, Giuseppe Vacanti, Ramses Günther, Jeroen Haneveld, Mark Olde Riekerink, Arenda Koelewijn, Coen van Baren, Dirk Kampf, Karl-Heintz Zuknik, Arnd Reutlinger, Finn E. Christensen, Desirée Della Monica Ferreira, Anders C. Jakobsen, Michael Krumrey, P. Müller, V. Burwitz, Giovanni Pareschi, M. Ghigo, M. Civitani, Laura Proserpio, Daniele Spiga, S. Basso, Bianca Salmaso, Daniele Gallieni, Matteo Tintori, Pierluigi Fumi, Francesco Martelli, Giancarlo Parodi, Ivan Ferrario, Ian M. Povey,
Future high energy astrophysics missions will require high performance novel X-ray optics to explore the Universe beyond the limits of the currently operating Chandra and Newton observatories. Innovative optics technologies are therefore being developed and matured by the European Space Agency (ESA) in collaboration with research institutions and industry, enabling leading-edge future science missions. Silicon Pore Optics (SPO) [1 to 21] and Slumped Glass Optics (SGO) [22 to 29] are lightweight high ...
Tópico(s): X-ray Spectroscopy and Fluorescence Analysis
2013 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Chiara Vergata, Felice Contaldi, Ivan Baccelli, Marcos Fernando Basso, Alberto Santini, Francesco Pecori, Matteo Buti, Alessio Mengoni, Francesca Vaccaro, Bárbara Baêsso Moura, Francesco Ferrini, Federico Martinelli,
Phylloremediation for the reduction of air particulate matter (PM) is an interesting opportunity to significantly contribute to improve the air quality of urban environment. The aim of this study was to: 1) gain insight into the gene regulatory networks modulating leaf responses to polluted air, 2) identify possible changes in the leaf microbiome due to particulate matter in the real urban environment. The leaf transcriptome and microbiome were analyzed for Photinia x fraseri L. plants cultivated ...
Tópico(s): Atmospheric chemistry and aerosols
2023 - Elsevier BV | Environmental and Experimental Botany
Riccardo Biavasco, Emanuele Lettera, Kety Giannetti, Diego Gilioli, Stefano Beretta, Anastasia Conti, Serena Scala, Daniela Cesana, Pierangela Gallina, Margherita Norelli, Luca Basso‐Ricci, Attilio Bondanza, Giulio Cavalli, Maurilio Ponzoni, Lorenzo Dagna, Claudio Doglioni, Alessandro Aiuti, Ivan Merelli, Raffaella Di Micco, Eugenio Montini,
ABSTRACT Activating mutations in the BRAF-MAPK pathway have been reported in histiocytoses, hematological inflammatory neoplasms characterized by multi-organ dissemination of pro-inflammatory myeloid cells. Here, we generate a humanized mouse model of transplantation of human hematopoietic stem and progenitor cells (HSPCs) expressing the activated form of BRAF ( BRAF V600E ). All mice transplanted with BRAF V600E -expressing HSPCs succumb to bone marrow failure, displaying myeloid-restricted hematopoiesis ...
Tópico(s): Immune cells in cancer
2021 - Nature Portfolio | Nature Communications
Valentina Capo, Sara Penna, Ivan Merelli, Matteo Barcella, Serena Scala, Luca Basso‐Ricci, Elena Draghici, Eleonora Palagano, Erika Zonari, Giacomo Desantis, Paolo Uva, Roberto Cusano, Lucia Sergi Sergi, Laura Crisafulli, Despina Moshous, Polina Stepensky, Katarzyna Drabko, Zühre Kaya, Ekrem Ünal, Alper Gezdirici, Giuseppe Menna, Marta Serafini, Alessandro Aiuti, Silvia L. Locatelli, Carmelo Carlo‐Stella, Ansgar Schulz, Francesca Ficara, Cristina Sobacchi, Bernhard Gentner, Anna Villa,
Allogeneic hematopoietic stem cell transplantation is the treatment of choice for autosomal recessive osteopetrosis caused by defects in the TCIRG1 gene. Despite recent progress in conditioning, a relevant number of patients are not eligible for allogeneic stem cell transplantation because of the severity of the disease and significant transplant-related morbidity. We exploited peripheral CD34+ cells, known to circulate at high frequency in the peripheral blood of TCIRG1-deficient patients, as a ...
Tópico(s): Immunotherapy and Immune Responses
2020 - Ferrata Storti Foundation | Haematologica
Tommy Alfaro Moya, Jonas Mattsson, Mats Remberger, Jeffrey H. Lipton, Dennis Dong Hwan Kim, Auro Viswabandya, Rajat Kumar, Wilson Lam, Arjun Law, Armin Gerbitz, Ivan Pašić, Igor Novitzky‐Basso, Fotios V. Michelis,
Abstract Introduction The literature comparing outcomes between myeloablative (MAC) and reduced intensity conditioning (RIC) for acute myeloid leukemia (AML) is conflicting. Methods We retrospectively analyzed 451 patients who underwent allogenic hematopoietic cell transplantation (alloHCT) for AML in complete remission (CR) with either RIC ( n = 331) or MAC ( n = 120) with the use of dual T‐cell depletion as graft‐versus‐host disease (GVHD) prophylaxis. Results Univariate analysis demonstrated nonrelapse mortality ( ...
Tópico(s): Immune Cell Function and Interaction
2023 - Wiley | European Journal Of Haematology
Nihar Desai, Majed Altareb, Mats Remberger, Carol Chen, Tommy Alfaro Moya, Eshrak Al‐Shaibani, Igor Novitzky‐Basso, Ivan Pašić, Wilson Lam, Fotios V. Michelis, Armin Gerbitz, Auro Viswabandya, Rajat Kumar, Dennis Dong Hwan Kim, Jeffrey H. Lipton, Jonas Mattsson, Arjun Law,
Post-transplant cyclophosphamide (PTCy) is a promising graft-versus-host disease (GvHD) prophylaxis in haploidentical and matched unrelated donor hematopoietic stem cell transplantation (HSCT), but its role in matched sibling donor (MSD) transplants remains unclear.We conducted a retrospective study of 413 MSD-HSCT patients receiving peripheral blood stem cell (PBSC) grafts from January 2010 to January 2023. Patients were categorized into four groups: Group I (CNI + MTX or MMF), Group II (CNI + MTX or MMF + ...
Tópico(s): Acute Lymphoblastic Leukemia research
2024 - Elsevier BV | Blood Advances
Lorenza Spagnuolo, Maura De Simone, Nicola Ivan Lorè, Ida De Fino, Veronica Basso, Anna Mondino, Cristina Cigana, Alessandra Bragonzi,
Abstract Patients with P. aeruginosa airways infection show markedly variable clinical phenotypes likely influenced by genetic backgrounds. Here, we investigated the cellular events involved in resistance and susceptibility to P. aeruginosa chronic infection using genetically distinct inbred mouse strains. As for patients, different murine genotypes revealed variable susceptibility to infection. When directly compared, resistant C3H/HeOuJ and susceptible A/J strains revealed distinct immune responsiveness ...
Tópico(s): Gut microbiota and health
2016 - Nature Portfolio | Scientific Reports
Georgina S. Daher-Reyes, Tae‐Hyung Kim, Igor Novitzky‐Basso, Kyuoung Ha Kim, Adam C. Smith, Tracy Stockley, José‐Mario Capo‐Chichi, Zeyad Al‐Shaibani, Ivan Pašić, Arjun Law, Wilson Lam, Fotios V. Michelis, Armin Gerbitz, Auro Viswabandya, Jeffrey H. Lipton, Rajat Kumar, Jonas Mattsson, Aaron D. Schimmer, Caroline McNamara, Tracy Murphy, Dawn Maze, Vikas Gupta, Hassan Sibai, Steven M. Chan, Karen Yee, Mark D. Minden, Zhaolei Zhang, Andre C. Schuh, Dennis Dong Hwan Kim,
Tópico(s): Myeloproliferative Neoplasms: Diagnosis and Treatment
2021 - Springer Nature | Bone Marrow Transplantation
Produção Nacional
Revisado por pares
Luana Henrichsen, José Antônio Gonzalez da Silva, Natiane Carolina Ferrari Basso, Juliana Aozane Da Rosa, Odenis Alessi, Ivan Ricardo Carvalho, Deivid Araújo Magano, Cristhian Milbradt Babeski,
Purpose: The objective of the study is to validate the technology of liquid nitrogen source by spraying of foliar absorption in comparison to the standard source urea of root absorption in the oat crop. Adapt the fuzzy logic model and training an artificial neural network to simulate oat productivity, under conditions of nitrogen use with the combined action of rainfall and thermal sum accumulated during the crop cycle. Method/design/approach: The study was conducted in Augusto Pestana, RS, Brazil, ...
Tópico(s): Crop Yield and Soil Fertility
2023 - CENTRO UNIVERSITARIO FEI | Revista de Gestão Social e Ambiental
María Queralt Salas, Ivan Pašić, Mats Remberger, Igor Novitzky‐Basso, Arjun Law, Wilson Lam, Carol Chen, Dennis Kim, Fotios V. Michelis, Armin Gerbitz, Auro Viswabandya, Jeffrey H. Lipton, Rajat Kumar, Jonas Mattsson,
The implementation of dual T-cell depletion comprising 4.5 mg/kg of antithymocyte globulin (ATG), post-transplantation cyclophosphamide, and cyclosporine A for reduced-intensity allogeneic hematopoietic cell transplantation (HCT) independent of donor source in 2015 significantly improved graft-versus-host disease (GVHD) control at our Institution. Further advances were made between 2017 to 2020 in supportive care of allogeneic HCT recipients and were the subject of this study, with 651 adults included. ...
Tópico(s): Renal Transplantation Outcomes and Treatments
2022 - Elsevier BV | Transplantation and Cellular Therapy
Produção Nacional
Revisado por pares
Márcia Sostmeyer Jung, José Antônio Gonzalez da Silva, Juliana Maria Fachinetto, Ivan Ricardo Carvalho, Osório Antônio Lucchese, Natiane Carolina Ferrari Basso, Camila Morizzo Copetti, L. Silva,
Objective: The objective of the study is to carry out a bibliographical review to understand the hydrological cycle and the importance of care of water for the maintenance of water resources and biodiversity in the pursuit of sustainability for present and future generations. Theoretical framework: Water is essential for human consumption, crop irrigation, animal watering, industrial production, energy generation and maintenance of biodiversity. However, water resources have been suffering anthropic ...
Tópico(s): Water Resource Management and Quality
2023 - CENTRO UNIVERSITARIO FEI | Revista de Gestão Social e Ambiental