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Artigo Revisado por pares

Sandro Rusconi, Yvonne Severne, Oleg Georgiev, Ivo Galli, Stefan Wieland,

A novel assay to study transcriptional regulation in vivo designated trans-activation-dependent replication (TDR) assay is based on the modulation of a simian virus 40 (SV40)-derive replication system. A mixture of four plasmids (pPARA + pCIS + pTRANS + pREF) is co-transfected into vertebrate cells. After appropriate incubation, the replication of the pPARA plasmid (containing an SV40 origin of replication) is measured with a simple enzymatic test. We demonstrate that the level of replication is dependent ...

Tópico(s): DNA Repair Mechanisms

1990 - Elsevier BV | Gene

Artigo Acesso aberto Revisado por pares

Anika Oellrich, Nigel Collier, Tudor Groza, Dietrich Rebholz‐Schuhmann, Nigam H. Shah, Olivier Bodenreider, Mary Regina Boland, Ivo Georgiev, Hongfang Liu, Kevin Livingston, Augustin Luna, Ann‐Marie Mallon, Prashanti Manda, Peter N. Robinson, Gabriella Rustici, Michelle Simon, Liqin Wang, Rainer Winnenburg, Michel Dumontier,

Phenotypes have gained increased notoriety in the clinical and biological domain owing to their application in numerous areas such as the discovery of disease genes and drug targets, phylogenetics and pharmacogenomics. Phenotypes, defined as observable characteristics of organisms, can be seen as one of the bridges that lead to a translation of experimental findings into clinical applications and thereby support 'bench to bedside' efforts. However, to build this translational bridge, a common and ...

Tópico(s): Cell Image Analysis Techniques

2015 - Oxford University Press | Briefings in Bioinformatics

Livro Acesso aberto

Jakob Dybdal Christensen, Jens Therkelsen, Ivo Georgiev, Henrik Sand,

The Nordic region attracts an increasing level of significant investments in new data centres. This seems to be no coincidence as the Nordics scores comparatively higher on factors such as Reliabl ...

Tópico(s): Distributed and Parallel Computing Systems

2018 - | TemaNord

Artigo Revisado por pares

Iliya Georgiev, Ivo Georgiev,

This paper presents a multi-tier model for secure computing as a teaching method platform. The security model is based on establishing the trustworthiness and role of each component in a distributed computing environment: trusted users, trusted servers, trusted administrators, untrusted client, untrusted communication media and intermediate systems, etc. The model provides a basis for teaching and for program system design. The security dimensions (both social and technical) can be considered in ...

Tópico(s): Cloud Data Security Solutions

2001 - Consortium for Computing Sciences in Colleges | Journal of computing sciences in colleges

Artigo Revisado por pares

Iliya Georgiev, Jivka Ovtcharova, Ivo Georgiev,

The dominating trend in Product Life Cycle Management (PLM) systems is to create distributed web-driven architectures with web services that would allow the related enterprises to operate as a single entity. The paper describes a modelling environment of web services to support easy prototyping of PLM systems. The application perspectives of two research problems are proposed: incorporating bottom-up ontology in the information web services for uniformity of product data access, and synchronisation ...

Tópico(s): Industrial Technology and Control Systems

2007 - Inderscience Publishers | International Journal of Product Lifecycle Management

Artigo Revisado por pares

Rayna Bryaskova, Nikoleta Philipova, Nikolay Georgiev, Ivo Lalov, Vladimir B. Bojinov, Christophe Detrembleur,

Abstract In this article we report on the facile preparation of photoactive antibacterial mussel inspired polymer coatings deposited on a stainless steel (SS) substrate from water based precursors. The coating is prepared by the sequential deposition of aqueous based solutions of an anchoring layer based on bio‐inspired glue, a cationic polymer bearing pendent catechols, a nanogel decorated by ortho ‐quinones and a photosensitizer of the aminoacridine type. This latter is grafted to the coating by ...

Tópico(s): Antimicrobial agents and applications

2021 - Wiley | Journal of Applied Polymer Science

Artigo

Muthiah Vaduganathan, Robert A. Harrington, Gregg W. Stone, Efthymios Deliargyris, Philippe Gabríel Steg, C. Michael Gibson, Christian W. Hamm, Matthew J. Price, Alberto Menozzi, Jayne Prats, Steven Elkin, Kenneth W. Mahaffey, Harvey D. White, Deepak L. Bhatt, Fernando Cura, M Ballarino, Aníbal Damonte, Diego Grinfeld, Carlos Alejandro Álvarez, Alberto Ocaña, A. Farshid, Brendan Gunalingam, Craig Jeurgens, Harry C. Lowe, H. Hallani, G. Nelson, Gishel New, Ronald Dick, Jeffrey Lefkovits, Stephen W. Duffy, Nick Bett, Raibhan Yadav, P. Garrahy, Ron Lehman, Philip E. Aylward, John D. Horowitz, M. Worthley, D. Cross, Jaime Rankin, Peter Thompson, Phil Roberts-Thomson, D. Cross, Rohan Jayasinghe, Con Aroney, Kurt Huber, F Leisch, Johann Altenberger, Georg Gaul, Thomas Neunteufl, Franz Weidinger, Herwig Schuchlenz, H. Wéber, Werner Benzer, Paulo Roberto Ferreira ROSSI, Breno Oliveira Almeida, Antônio Francisco Godinho, Fábio Vilas‐Boas, Luciano Janussi Vacanti, Renato Giestas Serpa, José Antonio Jatene, Gilmar Reis, Jamil Abdalla Saad, Marcos Maynar-Mariño, Roberto Botelho, Constantino Costantini, Ricardo Wang, Dalton Bertolim Précoma, M Rati, L. C. Bodanese, Euler Roberto Fernandes Manenti, João Paulo Zouvi, Rogério Tumelero, Arthur Herdy, Eulógio Martinez Filho, Antônio Carlos Carvalho, Roberto Alexandre Franken, Lawrence Title, Charles Lazzam, François Reeves, Tamaz Shaburishvili, Gulnara Chapidze, Merab Mamatsashvili, Irakli Khintibidze, Kurt Huber, Hans‐Georg Olbrich, Sabine Genth‐Zotz, S Moebius-Winkler, Michael Buerke, Stefan Hoffmann, Peter W. Radke, Helge Moellmann, Hugo A. Katus, HANS-FRIEDRICH VOEHRINGER, Christian Hengstenberg, Volker Klauß, Johannes Brachmann, Aftab Ahmad Khan, Sampath Kumar, P.P. Mohanan, Praveen Chandra, M. Bhaskar Rao, S. S. Ramesh, Keyur Parikh, Arun Srinivas, Nakul Sinha, G. K. Surya Prakash, Shirish Hiremath, Anil Mishra, Sanjeeb Roy, Kamal Sethi, Ashwani Mehta, Tejas Patel, Suman Bhandari, Milind Gadkari, Milind Gadkari, Stefano De Servi, Giuseppe Musumeci, Alberto Menozzi, Bernardo Cortese, Giancarlo Marenzi, Raffaele De Caterina, Ralph Stewart, Gerard Devlin, Scott A. Harding, John F. Elliott, Gerard T. Wilkins, D. Scott, Sławomir Dobrzycki, Waldemar Dorniak, Dariusz Dudek, Zbigniew Gąsior, Jarosław Hiczkiewicz, Zdzisława Kornacewicz‐Jach, Leszek Kubik, Krzysztof Kuc, Jerzy Kuźniar, Walentyna Mazurek, Jakub Ostrowski, Michał Tendera, Andrzej Wiśniewski, Elżbieta Zinka, Krzysztof Żmudka, Jana Pawła, Maciej Kośmider, Seweryna, Andrés Íñiguez, Rafael Melgares, Francisco Javier Goicolea, José Hernández, Javier Zueco, Igor Kraiz, Mykola Vatutin, Anatoliy Polyakov, Y.N. Sokolov, Kenneth W. House, Charles Campbell, Timothy Trageser, Kenneth W. Baran, Neal S. Kleiman, Roberto Medina, Roger Hill, M. Zubair Jafar, David Drenning, Herbert Ladley, Adil Al‐Nahhas, Alan Niederman, Amit Goyal, William B. Abernethy, Naseem Jaffrani, Richard Zelman, B J Negus, José Marquez, Ehtisham Mahmud, William J. French, John Paulowski, Charles V. Pollack, M Mines, Robert Federici, Marc J. Schweiger, Kalim Habet, Ofsman Quintana, Thomas W. Nygaard, Steve Orlow, Douglas Spriggs, Ivan Chavez, M. Warner, Richard Paulus, David Cochran, Cary Hirsch, Ajay Virmani, Peter Soukas, Nalin Srivastava, Laurent Ferrier, Annapoorna Kini, Mark A. Greenberg, Hartmut Herrmann, Valerian Fernandes, Barry Bertolet, Ron Waksman, Joseph B. Henderson, Harinder Gogia, Maged Amine, Kourosh Mastali, Thomas Stuckey, Peter Hui, Luigi Pacifico, Todd Caulfield, Wilson Ginete, William L. Ballard, Robert Iwaoka, Joseph Stella, Vijay K. Misra, Costa Andreou, Michele Voeltz, Wayne Batchelor, Cezar Staniloae, Sanford J. Gips, Jeffrey Kramer, Paul Mahoney, John Wang, Prospero Gogo, David G. Rizik, David G. Rizik, Rex J. Winters, G. Hunter Mackenzie, Stephen J. Jenkins, Paul Teirstein, Pierre P. Leimgruber, J. Christopher Scott, Seth Krauss, Steven Rohrbeck, Robert G. Martin, Gustavo Grieco, Louis Cannon, Don Westerhausen, F. David Fortuin, Steven P. Schulman, Joel Cohn, Brent McLaurin, Jorge Saucedo, Robert Wozniak, J. J. Hall, Kevin Marzo, Merrill Krolick, Lawrence W. Gimple, Eric Hockstad, Arsenio Rodriguez, John Kao, Adhir Shroff, Michael Attubato, Ramon Quesada, Ernesto Rivera, Larry S. Dean, Russell Raymond, Thomas M. Amidon, David Lee, Spencer King, John S. Douglas, Abnash C. Jain, J Patrick Kleaveland, Mitchell Driesman, Krishna Kumar, Glen J. Kowalchuk, Behzad Taghizadeh, Lawrence A. Barr, Keith Benzuly, Tarek Helmy, Duane S. Pinto, Joseph Aragon, Reginald Low, Phillip A. Horwitz, Thomas D. LeGalley, Dominick J. Angiolillo, Rajesh Sachdeva, Kenneth M. Kent, Luis Gruberg, Richard G. Bach, Thomas Pow, Charles O’Shaughnessy, Shing Chiu Wong, Saeed R. Shaikh, Arthur Reitman, Mark E. Lawrence, Fernando Cura, Alejandro García Escudero, Carlos Poy, Miguel Miceli, Antonio Pocoví, Hugo Londero, Jorge Baccaro, L. Z. Polonetsky, Aliaksey Karotkin, Leanid Shubau, Eduardo da Rosa Maffini, Bruno Martins Machado, José Airton,

Cangrelor, an intravenous, reversible P2Y12 antagonist, is approved for use in patients undergoing percutaneous coronary intervention (PCI). This study sought to evaluate the efficacy and safety of cangrelor compared with clopidogrel in subgroups that did and did not receive glycoprotein IIb/IIIa inhibitors (GPIs). This pooled, patient-level analysis of the 3 CHAMPION (Cangrelor versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition) trials analyzed all randomized patients who ...

Elsevier BV

Artigo Revisado por pares

Violeta Mihaylova, O. Kosseva, Iskren Kotzev, Georgi Georgiev, Ivo Kremensky, Т. Тодоров, Ivaylo Tournev,

Wilson disease (WD) is an inherited disorder of copper metabolism presenting with a variety of symptoms but commonly as a liver or neuropsychiatric disease. Abnormal evoked responses are constantly found among patients with neurologic manifestations and sometimes in patients with hepatic presentation or in presymptomatic siblings. The aim of our study was to assess visual and brainstem auditory evoked potentials (BAEP) in patients with various presentation of WD.Visual evoked potentials (VEP) were ...

Tópico(s): Heavy Metal Exposure and Toxicity

2020 - Lippincott Williams & Wilkins | Journal of Clinical Neurophysiology

Artigo Revisado por pares

Rayna Bryaskova, Nikoleta Philipova, Nikolai I. Georgiev, Damyan Ganchev, Ivo Lalov, Christophe Detrembleur,

Tópico(s): TiO2 Photocatalysis and Solar Cells

2023 - Springer Science+Business Media | Journal of Polymer Research

Artigo Revisado por pares

Irena Kamenova, M. Harrass, B. Lehmann, K. Friedrich, Ivo Ivanov, G. Georgiev,

Abstract Summary: The polyelectrolyte and antipolyelectrolyte effects on the degree of swelling (Q) and dehydration activation energy (E a ) of homo‐ and copolymer single and double networks, consisting of monomer units with polyelectrolyte and antipolyelectrolyte association abilities are determined and compared. An original correlation between Q and E a is outlined and explained.

Tópico(s): Advanced Polymer Synthesis and Characterization

2007 - Wiley | Macromolecular Symposia

Livro Acesso aberto

Jakob Nymann Rud, Morten Hørmann, Vibeke Hammervold, Ragnar Ásmundsson, Ivo Georgiev, Gillian Dyer, Simon Brøndum Andersen, Jes Erik Jessen, Pia Kvorning, Meta Reimer Brødsted,

This project explores the energy systems and their development towards 2035 in the West Nordic areas and the Arctic. The objective of the project was to contribute to a knowledge base that can be s ...

Tópico(s): Global Energy and Sustainability Research

2018 - | TemaNord

Artigo Acesso aberto Revisado por pares

Iliya Georgiev, Ivo Georgiev,

The paper proposes an information technology framework for the development of an embedded remote system for non-destructive observation and study of sensitive archaeological sites. The overall concept and motivation are described. The general hardware layout and software configuration are presented. The paper concentrates on the implementation of the following informational technology components: (a) a geographically unique identification scheme supporting a global key space for a key-value store; ( ...

Tópico(s): 3D Surveying and Cultural Heritage

2017 - Multidisciplinary Digital Publishing Institute | Computation

Artigo Revisado por pares

George Georgiev, Elena Kamenska, Elena Vassileva, Irena Kamenova, Ventsislava Georgieva, Stefko B. Iliev, Ivo A. Ivanov,

An explanation of the unique nonbiofouling properties of polyzwitterions (PZ) is proposed [in this paper, the term "polyzwitterion" is preferred to "polybetain"]. The existence of an osmotic component of the driving force of the antipolyelectrolyte effect (APE) and the parameters governing this phenomenon are quantitatively established. The correlation between this effect, which is specific of PZ only, and the PZ nonbiofouling properties is grounded.

Tópico(s): Advanced Polymer Synthesis and Characterization

2006 - American Chemical Society | Biomacromolecules

Artigo Acesso aberto Revisado por pares

Ivo Kabelka, Vasil N. Georgiev, Lisa Marx, Peter Pajtinka, Karl Lohner, Georg Pabst, Rumiana Dimova, Robert Vácha,

We previously speculated that the synergistically enhanced antimicrobial activity of Magainin 2 and PGLa is related to membrane adhesion, fusion, and further membrane remodeling. Here we combined computer simulations with time-resolved in vitro fluorescence microscopy, cryoelectron microscopy, and small-angle X-ray scattering to interrogate such morphological and topological changes of vesicles at nanoscopic and microscopic length scales in real time. Coarse-grained simulations revealed formation ...

Tópico(s): Biochemical and Structural Characterization

2022 - Elsevier BV | Biophysical Journal

Artigo Revisado por pares

Ivanka Dakova, Irina Karadjova, Ivo Ivanov, Ventsislava Georgieva, B. Evtimova, George Georgiev,

Ion-imprinted polymer (IIP) particles are prepared by copolymerization of methacrylic acid as monomer, trimethylolpropane trimethacrylate as crosslinking agent and 2,2′-azo-bis-isobutyronitrile as initiator in the presence of Cu(II), a Cu(II)–4-(2-pyridylazo)resorcinol (Cu(II)–PAR) complex, and PAR only. A batch procedure is used for the determination of the characteristics of the Cu(II) solid phase extraction from the IIP produced. The results obtained show that the Cu(II)–PAR IIP has the greatest ...

Tópico(s): Electrochemical Analysis and Applications

2006 - Elsevier BV | Analytica Chimica Acta

Artigo Revisado por pares

Elena Kamenska, Bistra Kostova, Ivo Ivanov, Dimitar Rachev, George Georgiev,

Abstract Stable poly{(vinyl acetate)‐ co ‐[3‐dimethyl(methacryloyloxyethyl)ammonium propanesulfonate]} latexes with different compositions were synthesized by emulsifier‐free emulsion copolymerization. An unusual “overshooting” behavior of the copolymer tablets is explained based on the formation of specific clusters of oppositely oriented dipoles. The variation of their concentration with the zwitterionic monomer unit fraction, ionic strength and temperature is responsible for the differences in the ...

Tópico(s): Hydrogels: synthesis, properties, applications

2007 - Wiley | Macromolecular Reaction Engineering

Artigo Revisado por pares

Elena Kamenska, Bistra Kostova, Ivo Ivanov, Dimitar Rachev, George Georgiev,

Very stable co-polymer (vinyl acetate (VA)-co-3-dimethyl(methacryloyloxyethyl) ammonium propane sulfonate (DMAPS) (p(VA-co-DMAPS)) latexes with different compositions have been synthesized by emulsifier-free emulsion co-polymerization. The dry p(VA-co-DMAPS)s have been used in the preparation of drug tablets for sustained Metoprolol tartrate release. It has been shown that the tablet swelling depends on the mol fraction of DMAPS monomer units (m(DMAPS)), pH and ionic strength (I). An original explanation, ...

Tópico(s): Analytical Chemistry and Chromatography

2009 - Taylor & Francis | Journal of Biomaterials Science Polymer Edition

Capítulo de livro Acesso aberto Revisado por pares

Ivo Malakov, Tzanko Georgiev, Velizar Zaharinov, Alexander Tzokev, Velislav Tzenov,

This article deals with an approach for demand modeling when designing size ranges of technical products.The proposed modeling approach is a stage of the size ranges optimization problem, and by it information can be obtained regarding the requested sizes and their respective quantities (demand).The approach is comprised of four main stagesmarket segmentation and choice of potential customers, collecting demand data, description and processing of the collected data, and determination of a demand ...

Tópico(s): Scheduling and Optimization Algorithms

2016 - DAAAM International Vienna | Annals of DAAAM for ... & proceedings of the ... International DAAAM Symposium

Livro Acesso aberto

Jakob Nymann Rud, Morten Hørmann, Vibeke Hammervold, Ragnar Ásmundsson, Ivo Georgiev, Gillian Dyer, Simon Brøndum Andersen, Jes Erik Jessen, Pia Kvorning, Meta Reimer Brødsted,

This project explores the energy systems and their development towards 2035 in the West Nordic areas and the Arctic. The objective of the project was to contribute to a knowledge base that can be s ...

Tópico(s): Global Energy and Sustainability Research

2018 - | TemaNord

Artigo Revisado por pares

Ivo A. Ivanov, Irena Kamenova, Ventsislava Georgieva, Elena Kamenska, George Georgiev,

The formation of pre-critical macromolecular self-assemblies resulting from a dipole–dipole interaction between the zwitterionic side groups of poly(dimethyl(methacryloxyethyl) ammonium propane sulfonate) in its aqueous, saltless solutions is proved viscosimetrically and by means of dynamic laser light scattering. The behavior of these self-assemblies in the presence of surfactants is determined by the interrelation of the two types of driving forces for self-association: dipole–dipole and hydrophobic ...

Tópico(s): Advanced Polymer Synthesis and Characterization

2006 - Elsevier BV | Colloids and Surfaces A Physicochemical and Engineering Aspects

Artigo Acesso aberto Revisado por pares

Georgi Georgiev, Ivo Dimitrov,

The study explores the effect of the European Structural and Investment Funds, intended to implement EU Environmental Policies on the development of the Bulgarian economy. Efforts are focused on measuring the strength and direction of the stochastic relationships between the absorbed funds provided by: the European Agricultural Fund for Rural Development (EAFRD), the European Maritime and Fisheries Fund (EMFF), the European Regional Development Fund (ERDF) and the Cohesion Fund (CF) on the Bulgarian ...

Tópico(s): Russia and Soviet political economy

2024 - EDP Sciences | BIO Web of Conferences

Artigo Acesso aberto Revisado por pares

Ivan Georgiev, Ivo Andreev,

The article is structured as follows. In section 1, the Introduction, a historical summary on the arising of the combinatorics is given. Next, a short review of the part of the combinatorics in the teaching of mathematics in Bulgaria is presented. At the beginning of section 2, combinatorial compounds, included in the Mathematics curriculum in Bulgaria, are reviewed. A new methodical scheme for the introduction of basic combinatorial compounds is proposed. Then, an alternative approach for solving ...

Tópico(s): History and Theory of Mathematics

2021 - UIKTEN | TEM Journal

Artigo

Yusuf Kayar, Aykut Özmen, Migena Gjoni, Nüket Bayram Kayar, Emrullah Erdem Duzgun, Ivo Georgiev, Ahmet Danalıoğlu,

Context The most common causes of acute pancreatitis are alcohol and biliary stones. Salmonella infections can rarely cause acute pancreatitis. Case report We presents the case of a 24-year old female patient who presented to our hospital with abdominal pain radiating to the back, nausea, vomiting and blurred consciousness. She was diagnosed with acute pancreatitis and septic shock caused by Salmonella infection. Conclusion Increased amylase and lipase levels are common in Salmonella infections. ...

Tópico(s): Pancreatic and Hepatic Oncology Research

2016 - Insight Medical Publishing | JOP, journal of the pancreas

Artigo Acesso aberto Revisado por pares

Veronika Dimitrova, Savina Stoitsova, Gergana Nenova, Maria Martinova, Milena Yakimova, Vanya Rangelova, Irina Georgieva, Ivo Georgiev, Stefka Krumova, A. Minkova, Nadezhda Vladimirova, Lubomira Nikolaeva–Glomb,

The communication practices of general practitioners in relation with vaccines have not been a topic of wide scientific interest. In this article, we outline them in the context of Bulgaria. A representative, cross-sectional, quantitative, face-to-face survey was conducted among 358 Bulgarian general practitioners in 2022 using simple random sampling. We conducted an exploratory factor analysis using questions about the role of the GPs, which measure models of communication. Based on the factor ...

Tópico(s): Catholicism, Bioethics, Media, Education

2023 - Multidisciplinary Digital Publishing Institute | Healthcare

Artigo Acesso aberto Revisado por pares

Veronika Dimitrova, Savina Stoitsova, Vanya Rangelova, Ralitsa Raycheva, Maria Martinova, Gergana Nenova, Milena Iakimova, Irina Georgieva, Ivo Georgiev, Stefka Krumova, A. Minkova, Nadezhda Vladimirova, Lubomira Nikolaeva–Glomb,

In a context of recently decreasing childhood immunization coverage and low uptake of COVID-19 vaccines in Bulgaria, this study measures vaccine hesitancy among general practitioners (GPs) in the country, as they are central to forming patients' attitudes. In 2022, a face-to-face survey was conducted through a simple random sample from an exhaustive national database of Bulgarian GPs. This study measured attitudes on vaccine importance, safety, and effectiveness, and attitudes toward the Bulgarian ...

Tópico(s): Hepatitis B Virus Studies

2023 - Taylor & Francis | Human Vaccines & Immunotherapeutics

Artigo Revisado por pares

Bistra Kostova, Elena Kamenska, Ivo Ivanov, Georgi Momekov, Dimitar Rachev, George Georgiev,

The aim of this study was to synthesize stable copolymer (vinyl acetate-co-3-dimethyl[methacryloyloxyethyl] ammonium propane sulfоnate) zwitterionic latex with different compositions for the first time by emulsifier-free emulsion copolymerization. Throughout the course of the study, a proposal was made for the explanation of the relationship between the “overshooting” phenomenon (a swelling kinetics with a maximum) and the specific self-association of the zwitterionic copolymers. The zwitterionic monomer ...

Tópico(s): Surfactants and Colloidal Systems

2008 - Taylor & Francis | Pharmaceutical Development and Technology

Artigo Acesso aberto Revisado por pares

Iliyana Petrova, Ivo Bogov, Alexander Alexandrov, G. Vladimirov, D Avramov, Hristo Mateev, Iva Paskaleva, B. Georgiev, Nina Gotcheva,

Abstract Introduction The Neutrophil Gellatinase Associated-Lipocalin (NGAL) as a biomarker for kidney damage is less investigated in terms of risk prediction. Purpose The aim of our study was to evaluate the diagnostic power of NGAL in detection of contrast-induced acute kidney injury (CI-AKI) and it's role for evaluation of the risk for serious renal dysfunction (SRD). Methods The study included high risk patients with chronic kidney disease (CKD) stage 2 and 3 undergoing coronary angiography and/ ...

Tópico(s): Trauma, Hemostasis, Coagulopathy, Resuscitation

2020 - Oxford University Press | European Heart Journal

Artigo

Deepak L. Bhatt, Philippe Gabríel Steg, Shamir R Mehta, Lawrence A. Leiter, Tabassome Simon, Kim Fox, Claes Held, Marielle Andersson, Anders Himmelmänn, Wilhelm Ridderstråle, Jersey Chen, Yang Song, Rafael Díaz, Shinya Goto, Stefan James, Kausik K. Ray, Alexander Parkhomenko, Mikhail Kosiborod, Darren K. McGuire, Robert A Harrington, Vladimir Santos, Ashit Jain, Irina Lendel, Michael Russo, W. Herbert Haught, Manuel Bouza, Harinder Gogia, Supratim Banerjee, George Kichura, Louis Kantaros, Francisco Padrón, R. Passi, Jay Stone, Michael Pursley, Michael D'Urso, Timothy J. Gardner, James Bennett, Khaled Nour, Satinder Saini, Wenwu Zhang, Dharam J. Kumbhani, Dustin Thomas, Dominick J. Angiolillo, Barry Bertolet, Amaury Roman-Miranda, Robert Black, Ramin Manshadi, Carlos Vaca, Antonio Blanco, Mark Napoli, David Brabham, Ayim Akyea-Djamson, Pratik Desai, Sudhir Prasada, AJIT Singh Khaira, Leslie B. Forgosh, Ira Lieber, Guillermo E. Umpierrez, Dinesh Singal, Juan Luis Londoño, Neil Fraser, Juan Manuel García‐Ruiz, Damaris Vega, Lilia Rodriguez, Christopher Brown, Faizullah Syed, Guarav Aggarwala, William Eaves, Michael Foster, Dinesh Gupta, David Avino, Wail Asfour, Glen Tonnessen, Xue‐Qiao Zhao, Narendra Singh, Andrew Brockmyre, Norman Lepor, Nicolas W. Shammas, David R. Blick, Steven Hearne, John Prodafikas, Edgar S. Carell, Mark Izzo, Amin H. Karim, Bosh Zakhary, Mahmoud Atieh, Steven B. Leichter, Charles Meadows, David R. Hotchkiss, Mazen Abu-Fadel, Alan Wiseman, Jeffrey Bander, Mahesh Shah, Subhash Banerjee, Ricky Ganim, Karen S Sopko, Misal Khan, Ramon L. Lloret, Troy Weirick, Rajendra H. Mehta, Udho Thadani, Anuj Bhargava, Mikhail Kosiborod, Jaynier Moya, Cezar Staniloae, Yamirka de la Caridad Rodríguez Guerra, Anil Chhabra, Douglas Kosmicki, Wassim Shaheen, Akber Mohammed, J'Cinda Bitters, Jan M. Pattanayak, Julián J. Javier, Sunny Srivastava, Roland T. Phillips, Jessie Al-Amin, Michael Lillestol, Patrick Simpson, Lydie Hazan, Amit N. Amin, Gopi Shah, Denes Korpas, B.‐A. Platt, Jim Dickert, Orlando Puente, Louis Hiotis, Timothy Doyle, Raj Rajan, Alan W Meholick, Christian Gring, Elie Hage-Korban, Robert Feldman, Harry T. Colfer, Samuel Butman, Malcolm Foster, Terence Hart, Randall Huling, Shervin Eshaghian, Ofsman Quintana, Deanna G. Cheung, F Handel, Mara Rodriguez, David Suh, Paul Gordon, Gregg S. Pressman, Michael Bauer, William J. French, Mark Barettella, Sridhar Chatrathi, Damodhar P. Suresh, Ronald Goldberg, Mark Huth, Liwa Younis, Aref Rahman, Richard Mascolo, Michelle Welch, Randeep Suneja, Stephen Smith, Scott Shurmur, John Agaiby, Ahmad Jingo, JM Johnston, Mary Beth, Anthony Vlastaris, Susan Kemp, Hamid Reza Taheri, Edward Pereira, Michael B. DeYoung, Zafir Hawa, Kausik K. Ray, Thomas Galski, Samer Garas, Madhu Reddy, Sanjeev Sharma, Joeseph Hargrove, Charles Treasure, Ronald G. Emerson, Tariq Haddad, Kathryn Rohr, L Levinson, Raul Gaona, Barry F. Uretsky, Hiralal Maheshwari, Denny Lee, Stephanie Kinnaman, Robert Singal, Jeffrey Geohas, Osvaldo Gigliotti, Ajit Raisinghani, Charanjit Khurana, Brent Hella, Michael A. Kelberman, Steven Voyce, Sanjay Singh, Eric Lo, Pradeep Singh, R. Goodfellow, Stuart Fischer, Richard S. Lorraine, Traci Turner, Jeffrey G. Shanes, Robert Busch, Robert Broker, Michelle Zaniewski, Kevin Pounds, Giselle Debs-Perez, Stephen Ong, Brad Frandsen, Douglas Fullington, Naseem Jaffrani, Ahtaram Khan, Marcus Lee, Joe Pouzar, George E. Revtyak, Julian Gonzalez, Samer Nakhle, Abel Murillo, Douglas Young, Sashi Makam, M.A. Syed, Kevin Woolf, Paul Grena, Sarab Alfata, Sharan Mahal, David A. Hoffman, Tinoy Kizhakekuttu, Joseph Deering, Janak R. Bhavsar, Scott Mikesell, William Wilson, E. Vance Wilson, Salah El, Francis G. Spinale, Vinod Kannarkat, Sunder Rao, Lenita Hanson, John Bertsch, Elena Gonzalez-Ortiz, Norma Severino, John Willis, Joel Schock, Ladan Bakhtari, Raúl J. Gazmuri, Saadat Ansari, Jason A. Hall, Arvind Mehta, Neal Shealy, Stuart Zarich, Deovrat Singh, Kishor Vora, Nabil Andrawis, Darron Molter, David Maron, José Cardona, Ronald D'Agostino, Tamjeed Arshad, Rodney A. Samaan, David A. Jones, Dale Presser, John A. Heath, Sandy Green, George Bittar, Sheldon D. Henry, David Korn, John Schmedtje, Venkatesh Nadar, Bruce Graham, Ajay Labroo, Leonardo Clavijo, Hal Roseman, Gilbert Ledesma, Robert L. Rosen, Isaac Dor, William Kirby, Jennefer Sutton, Frank Eder, Bruce Iteld, Jose Gomez-Cortes, Maurice Buchbinder, Joseph Kasper, Antonio Terrelonge, Gustavo Sánchez Torres, Ted Jagielo, Jose Antonio Carmona Álvarez, Yehuda Handelsman, Mario Guillen, Randall Richwine, Lorena Lewy-Alterbaum, Clinton N. Corder, Moogali Arvind, David Bolshoun, Magdy S. Mikhail, Stephen D. Minton, Odilon Alvarado, J. Dawn Abbott, Brett Cauthen,

Background Patients with stable coronary artery disease and diabetes with previous percutaneous coronary intervention (PCI), particularly those with previous stenting, are at high risk of ischaemic events. These patients are generally treated with aspirin. In this trial, we aimed to investigate if these patients would benefit from treatment with aspirin plus ticagrelor. Methods The Effect of Ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) was a phase 3 randomised, ...

Elsevier BV

Artigo Acesso aberto Revisado por pares

Ivo Ivanov, Ivanka Tsacheva, Vishnia Stoyanova, Miroslav Nikolov, Magdalena Tchorbadjieva, Svetla Petrova, Latchezar K. Christov, Ventsislava Georgieva, George Georgiev,

The amphiphilic polyzwitterion (PZ) poly(ethylene oxide-b-N,N-dimethyl(methacryloyloxyethyl)ammonium propanesulfonate), zwitterionic surfactant (ZS) n-dodecyl-N,N-dimethyl-3-ammonium-1-propanesulfonate, and zwitterionic monomer (ZM) N,N-dimethyl(methacryloyloxyethyl)ammonium propanesulfonate were analyzed for their suggested chaperone-like effect on the interaction of C1q and IgG. Our results proved that the PZ retarded the C1q interaction with IgG, demonstrating a specific protein-folding helper effect. ...

Tópico(s): Protein purification and stability

2009 - De Gruyter | Zeitschrift für Naturforschung C