Waldemar Januszczak, Tim Tezisler, John Dugdale, Michael Prescott, Iain Morrison, Barbara Hall, Judith O'Reilly Education Correspondent, Nigel Botherway, Lucas Hollweg, Kurt Schwitters, Fred Redwood, Jim Munro, Sean O'Brien, Nicholas Rufford, Kenny Farquharson, Tunbridge Wells, Dan Pearson, John Peter, Emma Moore, Amanda Ursell, Donna Leon, John Jay, Michael Owen, Hugh Brooks, Max Glaskin, Frank Whitford, Ray Spiller, Mark Franchetti Gomel, Ivo Tennant, Ferdinand Mount, Kevin Cameron, Sam Gilpin, David Smith, Kirstie Hamilton City Editor, Tim Richards, Edin Hamzic, Humphrey Carpenter, Chris Dignan, Melanie Phillips, Rob Wilson, Dillwyn Miles, Neil Wormald, Andrew Sullivan, Michael Thrasher, Clive Davis, Stephen Grey, Vincent Kearney, Mohamed Fofana, Joyce Kinrade, Robina Dam, Tony Allen-Mills, Simon Wilde, Andrew Larenz, Cornwall, Robert Sandall, Eleanor Mills, Anthony Sattin, Steve Farrar, Robert Winnett, Martin James, Irwin Stelzer, Neil Roland, Peter Wilson, Roger Anderson, Mark Ottaway, David Dougill, George Johannes Counsellor, York Membery, Taria Alexander, Hamish Scott, John Evans, Olivia Fane, Philip Kingsley, Thrasy Petropoulos, David Hewson, Miranda Suit, Cally Law, Margaret Coles, Hugh Canning, Hugh Mcllvanney, Alasdair Reid, David Caims, Peter Watson, Graham Duffill, Jeremy Clarkson, Joan Smythe, Peter Conradi, Nigel Williams, Louise Taylor, Thomas Coates, Edward Porter, Stewart Lee, Eben Black, Richard Marriott, Lucy Rees, Graham Otway, Pam Barren, Nick Gardner, Shelley von Strunckel, Mike Laws, Phillip Oppenheim, Lorna Macleod, Stuart Wavell, Paul Donovan, Steve Waugh, Caroline Aherne, Sue Lawrence, Paul Driver, Derek Clements, Michael Woodhead, Alan Brown John, Nicholas Hellen, Peter Windsor, Steven Downes, Richard Brooks, Ian Hawkey, Caroline Scott, James Tooley, Christopher Morgan, Anthony Sampson, B Simmonds, Alicia Wyllie, Mark Edwards, Kirstie Hamilton, Rebecca Bradley, Tom Shone, Sarah Gracie, Susan Clark, Michael Durham, Fiona McHugh, Lois Jones, Nicholas Rufford Home Affairs Editor, Leon Pein, Jane Lovell, Phil Baker, Karen Bayne, Jack Price, Jennifer Asiama, Truro, Sue Reid, Raymond Keene, Martin Ball, Rich Hall, Mark Tully, Cosmo Landesman, Zoe Brennan, Marie Colvin, Geoff Barton, Colin Smith, Diana Wright, Martin, Helen Hawkins, Stephen Jones, Richard Evans, Nick Cain, Stephen Bevan, Natalie Graham, Andrew Smith, Paul Nuki, Rachel Forder, Ian Coxon, Hugh McManners, F Scott Fitzgerald, Nicole Walford, Keith Wheatley, Claire Oldfield, Ned Sherrin, David Walsh, Zoë Linkson, Trevor Lewis, Jack Grimston, Colin McDowell, Jonathan Lawrence, Nick MacKinnon, Ron Clarke, Christopher Goodwin, Paul Kavanagh, Josh Salzmann, Mark Prigg, Michele Roberts, Nick Harvey, John Dugdate, Richard Woods, Roland White, Garth Alexander, Robin Mariar, Maurice Chittenden, Kevin Pratt, Barrie Penrose, Saul David, Richard Brooks Arts Editor, Collin Rallings, Andrew Lorenz Business Editor, Judith O'Reilly, Ray Hutton, Craig Lord, Mel Webb, Major General Peter Grant-Peterkin, Andrew Rogers, Louise Morris, Heather Laskey, Dr Mike Stroud, Frank McLynn, Michael Sheridan, Karen Kay, Sean Hargrave, Christine Webb, John Harlow, Godfrey Smith, Michael Austin, Lisa Brinkmarsh, Michael Hodges, Kate Thornton, Mandy Payne, John Waples, Hunter Davies, Andrew Stephen, A A Gill, Matthew Campbell, Brian Glanville, R Little, John Carey, David Hutcheon, Tom Robbins, Robert Johnston, Stephen Pettitt, John Spurling, Neil Buchanan, Sally Kinnes, Andrew Lorenz, D Spruce, Naomi Caine, David Wickers, Katie Grant, Roger Dobson, Tom Rhodes, Martin Ouvry, Nick Gardner Deputy Money Editor, Mark Hodson, Andrew Frankel, Joe Lane, Joe Lovejoy, Jonathan Futrell, Mickey Hutton, Rupert Steiner, Michael Harris, Hugh Pearman, Andrian Masters, Sumit Das Gupta, David Grylls, David Parsley, Penny Neary, David Smith Economics Editor, Tom Deveson, Harry Hill, Joe Jett, Joanna Simon, Stephen Boyd, Sir Ghillean Prance Professor, India Knight, Meg Mathews, Barry Newcombe, Dominic Rushe, Boris Schapiro, Karen Robinson, Susie Orbach, Stophen Pettitt,
... way out of video and become the new Van Damme? Cats The week's films That takes the ...
1999 - Gale Group | Sunday Times HA GDA
Raf Sciot, Paola Dal Cin, Rita De Vos, B. Van Damme, Ivo De Wever, Herman Van den Berghe, Valeer Desmet,
A typical case of alveolar soft‐part sarcoma was examined using ultrastructural, immunohistochemical and cytogenetic methods. Immunohistochemical stains were performed on frozen sections and showed strong desmin expression with the three anti‐desmin antibodies used. In addition, the tumour cells were weakly positive for vimentin and myosin. Neural markers were negative. Chromosomal analysis showed consistent involvement of 17q25—an abnormality which has been reported in another alveolar soft‐part ...
Tópico(s): Cardiac tumors and thrombi
1993 - Wiley | Histopathology
Paola Dal Cin, Raf Sciot, B. Van Damme, Ivo De Wever, Herman Van den Berghe,
Tópico(s): Sarcoma Diagnosis and Treatment
1995 - Elsevier BV | Cancer Genetics and Cytogenetics
Raf Sciot, Paola Dal Cin, Penelope Brock, Philippe Moerman, Boudewijn Van Damme, Ivo De Wever, Maria Casteels‐Van Daele, Herman Van den Berghe, Valeer Desmet,
A case of pleuropulmonary blastoma (childhood variant of pulmonary blastoma) was examined using histological, immunohistochemical, ultrastructural and cytogenetic methods. The tumour consisted of undifferentiated 'blastematous' areas admixed with zones of rhabdomyoblastic and chondroid differentiation and fascicular areas. Desmin and S-100 protein immunoreactivity confirmed the myogenic and cartilaginous differentiation. Ultrastructurally only undifferentiated mesenchymal cells were present. The cytogenetic ...
Tópico(s): Tracheal and airway disorders
1994 - Wiley | Histopathology
Tim Torsy, Renée Saman, Kurt Boeykens, Ivo Duysburgh, Nele Van Damme, Dimitri Beeckman,
Abstract Background Several studies have shown that the nose‐earlobe‐xiphoid distance (NEX) is inadequate to estimate the insertion length of nasogastric tubes. An alternative approach tested in these studies, which leads to > 90% well‐placed nasogastric tubes, used a corrected calculation of the NEX: (NEX × 0.38696) + 30.37. The primary aim of this study was to determine whether using the corrected NEX was more successful than the NEX in determining the insertion length. The secondary aim was to investigate ...
Tópico(s): Esophageal and GI Pathology
2018 - Wiley | Nutrition in Clinical Practice
Paola Dal Cin, Penelope Brock, Maria Casteels‐Van Daele, Ivo De Wever, Boudewijn Van Damme, Herman Van den Berghe,
Tópico(s): Tumors and Oncological Cases
1991 - Springer Science+Business Media | European Journal of Pediatrics
Paola Dal Cin, Raf Sciot, Ivo De Wever, Boudewijn Van Damme, Herman Van den Berghe,
Tópico(s): Cardiac tumors and thrombi
1994 - Elsevier BV | Cancer Genetics and Cytogenetics
Paola Dal Cin, Raf Sciot, Magdy Sayed Aly, Jan Delabie, Margareta Stas, Ivo De Wever, Boudewijn Van Damme, Herman Van den Berghe,
Ten desmoid tumors were examined by chromosome banding analysis and by in situ hybridization on short-term cultures and frozen sections. Trisomy 8 was detected in four out of ten tumors, of which only one had shown trisomy 8 by karyotype analysis. Since trisomy 8 has been reported in superficial fibromatoses, which are clinically distinct but histologically similar to desmoid tumors, the occurrence of trisomy 8 in both may be a further indication of a close relationship.
Tópico(s): Tumors and Oncological Cases
1994 - Wiley | Genes Chromosomes and Cancer
Paola Dal Cin, Patrick Kools, Raf Sciot, Ivo De Wever, Boudewijn Van Damme, Wim Van de Ven, Herman Van den Berghe,
Cytogenetic analysis of 184 adipose tissue tumors, 175 lipomas, and nine liposarcomas (LPS) showed the presence of a ring chromosome and/or a long marker chromosome in 10 cases with common histologic features such as atypical stromal cells with or without lipoblasts. In five of the cases, this appeared to be the sole cytogenetic abnormality. Fluorescence in situ hybridization (FISH) analysis with a microclone library specific for chromosome region 12q13-q15 showed extensive staining of the ring and ...
Tópico(s): RNA modifications and cancer
1993 - Elsevier BV | Cancer Genetics and Cytogenetics
Paola Dal Cin, Raf Sciot, C.D.M. FLETCHER, Carl Hilliker, Ivo De Wever, Boudewijn Van Damme, Herman Van den Berghe,
We found trisomy 21 as the sole chromosome abnormality in a solitary fibrous tumor arising at a nonpleural site. No cytogenetic investigation of solitary fibrous tumors has previously been reported.
Tópico(s): Tumors and Oncological Cases
1996 - Elsevier BV | Cancer Genetics and Cytogenetics
Andrea Bergamini, Marco Miniaci, Tommaso Delpero, Domenico Tallarico, Bart Van Damme, Gwenael Hannema, Ivo Leibacher, Armin Zemp,
The study of vibrational properties in engineered periodic structures relies on the early intuitions of Ha\"uy and Boscovich, who regarded crystals as ensembles of periodically arranged mass points interacting via attractive and repulsive forces. Contrary to electromagnetism, where mechanical properties do not couple to the wave propagation mechanism, in elasticity this paradigm inevitably led to low stiffness and high-density materials. Here, we transcend the Ha\"uy-Boscovich perception, proposing ...
Tópico(s): Cellular and Composite Structures
2019 - Nature Portfolio | Nature Communications
Paola Dal Cin, Marguerite Stas, Raf Sciot, Ivo De Wever, Boudewijn Van Damme, Herman Van den Berghe,
Abstract Cytogenetic investigation of a metastatic lesion appearing 31 years after nephrectomy allowed for the diagnosis of a renal cell carcinoma. The der(X)t(X1)(p11.2;q21.1) found in this case and review of the 14 other cases previously reported indicates that this chromosome lesion may characterize a specific subgroup of renal cell carcinoma, with distinct histology and age distribution that also can occur in females.
Tópico(s): Cancer Genomics and Diagnostics
1998 - Elsevier BV | Cancer Genetics and Cytogenetics
Paola Dal Cin, Penelope Brock, Magdy Sayed Aly, Maria Casteels‐Van Daele, Ivo De Wever, Boudewijn Van Damme, Herman Van Den Berghe,
Cytogenetic analysis of a right buttock mass from a 5-year-old boy showed translocation between an inverted chromosome 1 and a chromosome 13 as the sole cytogenetic abnormality. The breakpoint 13q14 appears to be the same as in previously reported cases of rhabdomyosarcoma (mostly of the alveolar type), but does not show involvement of 2q37. We suggest that this translocation may be a variant of the classical t(2;13)(q37;q14) found in rhabdomyosarcoma.
Tópico(s): Metastasis and carcinoma case studies
1991 - Elsevier BV | Cancer Genetics and Cytogenetics
Paola Dal Cin, Stephane Van Gool, Penelope Brock, Willem Proesmans, Maria Casteels‐Van Daele, Ivo De Wever, Luc Baert, Boudewijn Van Damme, Herman Van den Berghe,
Tópico(s): Renal cell carcinoma treatment
1991 - Elsevier BV | Cancer Genetics and Cytogenetics
Paola Dal Cin, Raf Sciot, Ivo De Wever, B. Van Damme, Herman Van den Berghe,
No AccessJournal of UrologyClinical Urology: Case Report1 Jul 1996Diagnosis of Primary Renal Cell Carcinoma in a Left Supraclavicular Lymph Node by Chromosome Analysis P. Dal Cin, R. Sciot, I. De Wever, B. Van Damme, and H. Van Den Berghe P. Dal CinP. Dal Cin More articles by this author , R. SciotR. Sciot More articles by this author , I. De WeverI. De Wever More articles by this author , B. Van DammeB. Van Damme More articles by this author , and H. Van Den BergheH. Van Den Berghe More articles by this ...
Tópico(s): Cancer Genomics and Diagnostics
1996 - Lippincott Williams & Wilkins | The Journal of Urology
Paola Dal Cin, Raf Sciot, Ivo De Wever, Penelope Brock, Maria Casteels‐Van Daele, Boudewijn Van Damme, Herman Van den Berghe,
From cytogenetic and immunohistochemical findings in a primary giant cell fibrosarcoma and its recurrence, it is further demonstrated that a close relationship exists between this tumor and dermatofibrosarcoma protuberans. Both tumors express CD34 and show rearrangements of chromosomes 17 and 22. Genes Chromosom Cancer 15:73–75 (1996). © 1996 Wiley-Liss, Inc.
Tópico(s): Oral and Maxillofacial Pathology
1996 - Wiley | Genes Chromosomes and Cancer
Paola Dal Cin, Ivo De Wever, Raymond Aerts, Boudewijn Van Damme, Herman Van den Berghe,
Abstract Epithelioid smooth muscle tumor is a rare low grade malignancy that usually occurs in the gastrointestinal tract. No chromosome studies of this tumor have been reported so far. We found trisomy 8 as the sole chromosome anomaly in a large hepatic epithelioid smooth muscle tumor.
Tópico(s): Tuberous Sclerosis Complex Research
1991 - Wiley | Genes Chromosomes and Cancer
Ivo Vojtek, Heidi J. Larson, Stanley A. Plotkin, Pierre Van Damme,
Developing and implementing new immunization policies in response to shifting epidemiology is a critical public health component. We adopted a mixed-methods approach (via narrative literature review [101 articles] and 9 semi-structured interviews) to evaluate policy development in response to shifting measles epidemiology in six European countries (Italy, Belgium, Germany, Romania, UK, and Ukraine); where policies and strategies have evolved in response to country-specific disease and vaccination patterns. ...
Tópico(s): Influenza Virus Research Studies
2022 - Taylor & Francis | Human Vaccines & Immunotherapeutics
Jan Tauchen, Ivo Doskočil, Cecilia Caffi, Ermias Lulekal, Petr Maršík, Jaroslav Havlík, Patrick Van Damme, Ladislav Kokoška,
Identification and characterization of natural products with antioxidant and anti-proliferative activity has received much interest over the past few years. Ethiopia is one of the developing countries which have enormous diversity of plants and yet majority stays scientifically neglected and undiscovered. In this study, the ethanol extracts of 18 Ethiopian wild medicinal plants were investigated for their in vitro antioxidant and anti-proliferative potential. For this purpose DPPH (2,2-diphenyl-1- ...
Tópico(s): Natural Antidiabetic Agents Studies
2015 - Elsevier BV | Industrial Crops and Products
Jan Tauchen, Ludvik Bortl, Lukáš Huml, Petra Mikšátková, Ivo Doskočil, Petr Maršík, Pablo Pedro Villegas Panduro, Ymber Bendezu Flores, Patrick Van Damme, Bohdan Lojka, Jaroslav Havlík, Oldřich Lapčı́k, Ladislav Kokoška,
Among 23 extracts of medicinal and edible plants tested, Mauritia flexuosa L.f., Arecaceae, showed significant antioxidant ability (DPPH and ORAC = 1062.9 and 645.9 ± 51.4 μg TE/mg extract, respectively), while Annona montana Macfad., Annonaceae, demonstrated the most promising anti-proliferative effect (IC50 for Hep-G2 and HT-29 = 2.7 and 9.0 μg/ml, respectively). However, combinatory antioxidant/anti-proliferative effect was only detected in Oenocarpus bataua Mart., Arecaceae (DPPH = 903.8 and ORAC = 1024 ...
Tópico(s): Phytochemistry and Biological Activities
2016 - Springer Science+Business Media | Revista Brasileira de Farmacognosia
Raf Sciot, Paola Dal Cin, Christopher D.�M. Fletcher, Ivo De Wever, Robin Vos, Boudewijn Van Damme, Herman Van den Berghe,
A recurrent malignant spindle cell neoplasm of the kidney, occurring in a 11‐year‐old girl and corresponding to a malignant peripheral nerve sheath tumour is reported. The neurogenic differentiation was substantiated by the presence of PGP 9.5 neurofilament and S‐100 protein positivity and by the ultrastructural features. Cytogenetic analysis revealed monosomy of chromosome 22 in the tumour while the constitutional karyotype was normal. Primary malignant peripheral nerve sheath tumour of the kidney ...
Tópico(s): Neurofibromatosis and Schwannoma Cases
1995 - Wiley | Histopathology
... als Apotheker neue Darstellungen . Der Flämische Künstler Frank-Ivo Van Damme hat 1984 zwei Linoleum-Stiche über das Thema « ...
Tópico(s): Historical, Religious, and Philosophical Studies
1985 - British Society for the History of Pharmacy | Revue d histoire de la pharmacie
Robert Prior, Alessio Silva, Tim Vangansewinkel, Jakub Idkowiak, Arun Kumar Tharkeshwar, Tom P. Hellings, Iliana Michailidou, Jeroen Vreijling, Maarten Loos, Bastijn Koopmans, Nina Vlek, Cedrick Agaser, Thomas B. Kuipers, Christine Michiels, Elisabeth Rossaert, Stijn Verschoren, Wendy Vermeire, Vincent de Laat, Jonas Dehairs, Kristel Eggermont, Diede van den Biggelaar, Adekunle T. Bademosi, Frédéric A. Meunier, Martin vandeVen, Philip Van Damme, Hailiang Mei, Johannes V. Swinnen, Ivo Lambrichts, Frank Baas, Kees Fluiter, Esther Wolfs, Ludo Van Den Bosch,
Abstract Charcot–Marie–Tooth disease type 1A (CMT1A) is the most common inherited peripheral neuropathy caused by a 1.5 Mb tandem duplication of chromosome 17 harbouring the PMP22 gene. This dose-dependent overexpression of PMP22 results in disrupted Schwann cell myelination of peripheral nerves. To obtain better insights into the underlying pathogenic mechanisms in CMT1A, we investigated the role of PMP22 duplication in cellular homeostasis in CMT1A mouse models and in patient-derived induced pluripotent ...
Tópico(s): Autophagy in Disease and Therapy
2024 - Oxford University Press | Brain
Laura Chinenye Ilogu, Olga Lugovska, Ivo Vojtek, Anna Prugnola, Andrea Callegaro, Sara Mazzilli, Pierre Van Damme,
Young adults are the future vaccine decision-makers as parents or health-care professionals. To understand their attitudes and behaviors toward vaccination, we conducted a cross-sectional survey of 2079 students attending the University of Antwerp, Belgium and the University of Pisa, Italy. Principal component analysis was used to investigate associations between survey responses and the intent to vaccinate. Vaccination knowledge, attitudes, and behaviors among university students in Italy and Belgium ...
Tópico(s): Misinformation and Its Impacts
2021 - Taylor & Francis | Human Vaccines & Immunotherapeutics
Andrea Callegaro, Laura Chinenye Ilogu, Olga Lugovska, Sara Mazzilli, Anna Prugnola, Pierre Van Damme, Ivo Vojtek,
Abstract Background Immunisation programs are still facing substantial challenges in achieving target coverage rates. This has been attributed to the growing negative individual vaccination attitudes and behaviours. Most of the current studies assessing vaccination knowledge, attitude and beliefs targets adults. However, young people represent future parents and health care professionals. The objective of this study was to investigate vaccination knowledge attitudes and behaviours among university ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2020 - Oxford University Press | European Journal of Public Health
Paola Dal Cin, Raf Sciot, Ivo De Wever, B. Van Damme, Herman Van den Berghe,
Tópico(s): Cancer Genomics and Diagnostics
1996 - Lippincott Williams & Wilkins | The Journal of Urology
Paola Dal Cin, Raf Sciot, Ivo De Wever, Penelope Brock, Maria Casteels‐Van Daele, Boudewijn Van Damme, Herman Van den Berghe,
Tópico(s): Oral and Maxillofacial Pathology
1996 - Wiley | Genes Chromosomes and Cancer
Ivo N. van Schaik, Orell Mielke, Arman Sabet, Koshy George, L. Jackson Roberts, Ross Carne, Stefan Blum, Robert D. Henderson, Philip Van Damme, Jelle Demeestere, Sandrine Larue, Catherine-Andree Pinard D'Amour, Vera Bril, Ari Breiner, Pavel Kunc, Martin Vališ, J Süssová, Tomas Kalous, Radomír Taláb, Michal Bednar, Toomas Toomsoo, Inna Rubanovits, Katrin Gross‐Paju, Ulvi Sorro, Mika Saarela, Mari Auranen, Jean Pouget, Shahram Attarian, Gwendal Le Masson, Anne-Cécile Wielanek-Bachelet, Claude Desnuelle, Émilien Delmont, Pierre Clavelou, D Aufauvre, Jens Schmidt, Jana Zschuentssch, Claudia Sommer, Daniela Kramer, Olaf Hoffmann, Carsten Goerlitz, Judith Haas, Marios Chatzopoulos, Min‐Suk Yoon, Ralf Gold, Peter Berlit, Andrea Jaspert-Grehl, David Liebetanz, Anna Kutschenko, Martin Stangel, Corinna Trebst, Petra Baum, Florian Then Bergh, Juliane Klehmet, Andreas Meisel, Fabian Klostermann, Johanna Oechtering, Helmar C. Lehmann, Michael Schroeter, Tim Hagenacker, Daniel Mueller, Anne‐Dorte Sperfeld, Florian Bethke, Hans‐Peter Hartung, Vivian E. Drory, Avi A. Algom, David Yarnitsky, Beth B. Murinson, Antonio Di Muzio, Fausta Ciccocioppo, Sandro Sorbi, Sabrina Matà, Angelo Schenone, Marina Grandis, Giuseppe Lauria, Daniele Cazzato, Giovanni Antonini, Stefania Morino, Dario Cocito, Maurizio Zibetti, Takanori Yokota, Takuya Ohkubo, Takashi Kanda, Motoharu Kawai, Kenichi Kaida, Hiroyuki Onoue, Satoshi Kuwabara, Masahiro Mori, Masahiro Iijima, Ken Ohyama, Gen Sobue, Masayuki Baba, Masahiko Tomiyama, Kazutoshi Nishiyama, Tsugio Akutsu, Kazumasa Yokoyama, Kazuaki Kanai, Ivo N. van Schaik, Filip Eftimov, Nicolette C. Notermans, Nora A. Visser, Catharina G. Faber, Janneke G. J. Hoeijmakers, Ingemar S.J. Merkies, Nan van Geloven, Konrad Rejdak, Urszula Chyrchel-Paszkiewicz, Carlos Casanovas Pons, Maria Antònia Albertí Aguiló, Josep Gámez, María José Figueras, C. Márquez Infante, S. Benítez Rivero, Michael P. Lunn, Jasper M. Morrow, David Gosal, Timothy Lavin, Isaac Melamed, Alessandro Testori, Senda Ajroud‐Driss, Daniela M. Menichella, Ericka Simpson, Eugene C. Lai, Mazen M. Dimachkie, Richard J. Barohn, Said R. Beydoun, Harpreet K Johl, Dale J. Lange, Alexander Shtilbans, Suraj Muley, Shafeeq Ladha, Miriam Freimer, John T. Kissel, Norman Latov, Russell L. Chin, Eroboghene E. Ubogu, Sandi Mumfrey, T. Hermanth P. Rao, Paul C. MacDonald, Khema R. Sharma, G P Losada González, Jeffrey A. Allen, David Walk, Lisa D. Hobson‐Webb, Karissa Gable, Richard A. Lewis, David R. Cornblath, J.P. Lawo, Michaela Praus, Billie L. Durn, Orell Mielke,
We thank Ravi Uniyal and colleagues for their comments on our results from the PATH trial1van Schaik IN Bril V van Geloven N et al.Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (PATH): a randomised, double-blind, placebo-controlled, phase 3 trial.Lancet Neurol. 2018; 17: 35-47Summary Full Text Full Text PDF PubMed Scopus (163) Google Scholar on subcutaneous immunoglobulin (SCIg) for maintenance treatment in chronic inflammatory demyelinating ...
Tópico(s): Nerve injury and regeneration
2018 - Elsevier BV | The Lancet Neurology
Ivo N. van Schaik, Vera Bril, Nan van Geloven, Hans‐Peter Hartung, Richard A. Lewis, Gen Sobue, John‐Philip Lawo, Michaela Praus, Orell Mielke, Billie L. Durn, David R. Cornblath, Ingemar S. J. Merkies, Arman Sabet, Koshy George, L. Jackson Roberts, Ross Carne, Stefan Blum, Robert D. Henderson, Philip Van Damme, Jelle Demeestere, Sandrine Larue, Catherine-Andree Pinard D'Amour, Vera Bril, Ari Breiner, Pavel Kunc, Martin Vališ, J Süssová, Tomas Kalous, Radomír Taláb, Michal Bednar, Toomas Toomsoo, Inna Rubanovits, Katrin Gross‐Paju, Ulvi Sorro, M. Saarela, Mari Auranen, Jean Pouget, Shahram Attarian, Gwendal Le Masson, Anne-Cécile Wielanek-Bachelet, Claude Desnuelle, Émilien Delmont, Pierre Clavelou, D Aufauvre, Jens Schmidt, Jana Zschuentssch, Claudia Sommer, Daniela Kramer, Olaf Hoffmann, Carsten Goerlitz, Jürgen Haas, Marios Chatzopoulos, Richard S. Yoon, Ralf Gold, Peter Berlit, Andrea Jaspert-Grehl, David Liebetanz, Anna Kutschenko, Martin Stangel, Corinna Trebst, Petra Baum, Florian Then Bergh, Juliane Klehmet, Andreas Meisel, Fabian Klostermann, Johanna Oechtering, Helmar C. Lehmann, Michael Schroeter, Tim Hagenacker, Daniel Mueller, A.D Sperfeld, F. Bethke, Vivian E. Drory, Avi A. Algom, David Yarnitsky, Beth B. Murinson, Antonio Di Muzio, Fausta Ciccocioppo, Sandro Sorbi, Sabrina Matà, Angelo Schenone, Marina Grandis, Giuseppe Lauria, Daniele Cazzato, Giovanni Antonini, Stefania Morino, Dario Cocito, Maurizio Zibetti, Takanori Yokota, Takuya Ohkubo, Takashi Kanda, M Kawai, Kenichi Kaida, Hiroyuki Onoue, Satoshi Kuwabara, Masahiro Mori, Masahiro Iijima, Ken Ohyama, Masayuki Baba, Masahiko Tomiyama, Kazutoshi Nishiyama, Tsugio Akutsu, Kazuhito Yokoyama, Kazuaki Kanai, Ivo N. van Schaik, Filip Eftimov, Nicolette C. Notermans, Nora A. Visser, Catharina G. Faber, Janneke G. J. Hoeijmakers, Konrad Rejdak, Urszula Chyrchel-Paszkiewicz, Carlos Casanovas Pons, Maria Alberti Aguilo, Josep Gámez, Maria Salvadó Figueras, C. Márquez Infante, S. Benítez Rivero, Michael P. Lunn, Jasper M. Morrow, David Gosal, Timothy Lavin, Isaac Melamed, Alessandro Testori, Senda Ajroud‐Driss, Daniela M. Menichella, Ericka Simpson, Eugene C. Lai, Mazen M. Dimachkie, Richard J. Barohn, Said R. Beydoun, Harpreet K Johl, Dale J. Lange, Alexander Shtilbans, Suraj Muley, Shafeeq Ladha, Miriam Freimer, J. T. Kissel, Norman Latov, Russell L. Chin, Eroboghene E. Ubogu, Sandi Mumfrey, TRamesh Kumar Rao, Paul C. MacDonald, Khema R. Sharma, G. Gonzalez, Jeffrey A. Allen, David Walk, Lisa D. Hobson‐Webb, Karissa Gable,
Approximately two-thirds of patients with chronic inflammatory demyelinating polyneuropathy (CIDP) need long-term intravenous immunoglobulin. Subcutaneous immunoglobulin (SCIg) is an alternative option for immunoglobulin delivery, but has not previously been investigated in a large trial of CIDP. The PATH study compared relapse rates in patients given SCIg versus placebo.Between March 12, 2012, and Sept 20, 2016, we studied patients from 69 neuromuscular centres in North America, Europe, Israel, Australia, ...
Tópico(s): Myasthenia Gravis and Thymoma
2017 - Elsevier BV | The Lancet Neurology
Richard AC Hughes, Marinos C. Dalakas, Ingemar S. J. Merkies, Norman Latov, Jean‐Marc Léger, Eduardo Nobile‐Orazio, Gen Sobue, Angela Genge, David R. Cornblath, Martin Merschhemke, Carolyn M. Ervin, Catherine Agoropoulou, Hans‐Peter Hartung, Timothy Day, Judith Spies, L. Jackson Roberts, Philip Van Damme, P Y Van den Bergh, Alain Maertens De Noordhout, Annie Dionne, Sandrine Larue, Rami Massie, Michel Melanson, William Camu, de Sèze, Gwendal Le Masson, Jean Pouget, Jens Schmidt, Vasilios Κ. Kimiskidis, Joab Chapman, Vivian E. Drory, Raffaella Fazio, Francesca Gallia, Susumu Kusunoki, Masahiro Mori, Masahiro Iijima, Tomoko Okamoto, Masayuki Baba, Catharina G. Faber, Ivo N. van Schaik, Waldemar Fryze, Ewa Motta, Krzysztof Selmaj, Carlos Casasnovas, A. Guerrero Sola, Isabel Illa, James Holt, James Miller, Michael P. Lunn, Thomas H. Brannagan, M. Brown, J Kelemen, Stanley Iyadurai, Kourosh Rezania, Khema R. Sharma, Rup Tandan, Mark Gudesblatt, V. Lawson, Anthony A. Amato,
Background Fingolimod is approved for the treatment of relapsing-remitting multiple sclerosis and was effective in experimental autoimmune neuritis in rats, a possible model for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). We aimed to evaluate the efficacy of fingolimod in delaying disability progression in patients with CIDP who withdrew from currently effective treatments (intravenous immunoglobulin [IVIg] or corticosteroids). Methods This double-blind, multicentre, randomised, ...
Tópico(s): Multiple Sclerosis Research Studies
2018 - Elsevier BV | The Lancet Neurology