Małgorzata Kloc, Izabela Jędrzejowska, Wacław Tworzydło, Szczepan M. Biliński,
Tópico(s): Insect and Arachnid Ecology and Behavior
2014 - Elsevier BV | Arthropod Structure & Development
Janka Vašková, Zuzana Klepcová, Ivana Špaková, Peter Urdzík, Jana Štofilová, Izabela Bertková, Marek Kľoc, Miroslava Rabajdová,
Oxidative stress (OS) has an important role in female reproduction, whether it is ovulation, endometrium decidualization, menstruation, oocyte fertilization, or development andimplantation of an embryo in the uterus. The menstrual cycle is regulated by the physiological concentration of reactive forms of oxygen and nitrogen as redox signal molecules, which trigger and regulate the length of individual phases of the menstrual cycle. It has been suggested that the decline in female fertility is modulated ...
Tópico(s): Genomics, phytochemicals, and oxidative stress
2023 - Multidisciplinary Digital Publishing Institute | Antioxidants
Rafał P. Piprek, Małgorzata Kloc, Klaudia Porębska, Paulina C. Mizia, Izabela Rams‐Pociecha, Jacek Z. Kubiak,
Testicular macrophages are the principal immune cells in the testis. In addition to their classical immune roles, they regulate male hormone synthesis by Leydig cells, regeneration of Leydig cells, spermatogonia proliferation and differentiation, maintenance of testis-specific environment for sperm formation, and testis development. The juvenile and adult testes contain two distinct macrophage populations with unique tissue localization, genetic markers, morphology, and function. The interstitial ...
Tópico(s): Epigenetics and DNA Methylation
2024 - Springer Science+Business Media | Results and problems in cell differentiation
Rafał P. Piprek, Izabela Rams‐Pociecha, Robert Zdanowski, Małgorzata Kloc, Jacek Z. Kubiak,
Cell to cell interactions are crucial for morphogenesis and tissue formation. Desmoplakin (encoded by the Dsp gene) is a component of desmosomes and anchors the transmembrane adhesion proteins to the cytoskeleton. Its role in gonad development remains vague. To study the role of desmoplakin in gonad development, we used a tissue-specific knockout of the Dsp gene in the NR5A1+ somatic cells of the gonads. We show here that desmoplakin is necessary for the survival of germ cells in fetal testes and ...
Tópico(s): Sperm and Testicular Function
2022 - Bioscientifica | Reproduction