Anatoly Shuster, David Landry,
... pediatric patients with Chiari malformation type IArnold H.Menezes, Jeremy D. W.Greenlee, Brian J.Dlouhy2018Jul1 | Journal of ... association with syringobulbia and syringocephaly: case reportArnold H.Menezes, Jeremy D. W.Greenlee, Reid A.Longmuir, Daniel R. ...
Tópico(s): Spinal Cord Injury Research
2013 - Radiological Society of North America | Radiology
Arnold H. Menezes, Jeremy D.W. Greenlee, Brian J. Dlouhy,
OBJECTIVE Syringobulbia (SB) is a rare entity, with few cases associated with Chiari malformation type I (CM-I) in the pediatric population. The authors reviewed all pediatric cases of CM-I-associated SB managed at their institution in order to better understand the presentation, treatment, and surgical outcomes of this condition. METHODS A prospectively maintained institutional database of craniovertebral junction abnormalities was analyzed to identify all cases of CM-I and SB from the MRI era (i. ...
Tópico(s): Head and Neck Surgical Oncology
2018 - | Journal of Neurosurgery Pediatrics
Arnold H. Menezes, Jeremy D.W. Greenlee, Reid Longmuir, Daniel R. Hansen, Kingsley Abode-Iyamah,
The authors present the case of a 14-year-old boy with holocord syringohydromyelia extending into the brainstem, cerebral peduncle, internal capsule, and cerebral cortex. At the posterior fossa exploration, an opaque thickened arachnoid with occlusion of the foramen of Magendie was encountered. Careful documentation of postoperative regression of the syringocephaly, syringobulbia, and syringohydromyelia was made. The pathophysiology is discussed.
Tópico(s): Fetal and Pediatric Neurological Disorders
2015 - | Journal of Neurosurgery Pediatrics
Lucie Lerebourg, Maxime L’Hermette, Charlotte Menez, Jérémy Coquart,
This systematic review evaluated the literature pertaining to the effect of shoes on lower limb venous status in asymptomatic populations during gait or exercise. The review was conducted in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The PubMed-NCBI, EBSCO Host, Cochrane Library and Science Direct databases were searched (March 2019) for words around two concepts: shoes and venous parameters. The inclusion criteria were as follows: (1) the ...
Tópico(s): Lower Extremity Biomechanics and Pathologies
2020 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Antonio Luis de O. A. Petersen, Benjamin Cull, Beatriz Dias, Luana C. Palma, Yasmin da Silva Luz, Juliana Perrone Bezerra de Menezes, Jeremy C. Mottram, Patrícia Sampaio Tavares Veras,
The heat shock protein 90 (Hsp90) is thought to be an excellent drug target against parasitic diseases. The leishmanicidal effect of an Hsp90 inhibitor, 17-N-allylamino-17-demethoxygeldanamycin (17-AAG), was previously demonstrated in both in vitro and in vivo models of cutaneous leishmaniasis. Parasite death was shown to occur in association with severe ultrastructural alterations in Leishmania, suggestive of autophagic activation. We hypothesized that 17-AAG treatment results in the abnormal activation ...
Tópico(s): Trypanosoma species research and implications
2021 - Multidisciplinary Digital Publishing Institute | Microorganisms
Francisco Menezes Brandão, Jeremy Castro, Manuela Pecegueiro,
Contact DermatitisVolume 9, Issue 4 p. 332-333 Photoallergy – musk ambrette F. Menezes Brandão, F. Menezes Brandão Dermatology Department, Santa Maria Hospital, 1699 Lisbon, PortugalSearch for more papers by this authorJ. Cirne De Castro, J. Cirne De Castro Dermatology Department, Santa Maria Hospital, 1699 Lisbon, PortugalSearch for more papers by this authorM. Pecegueiro, M. Pecegueiro Dermatology Department, Santa Maria Hospital, 1699 Lisbon, PortugalSearch for more papers by this author F. Menezes ...
Tópico(s): Skin Protection and Aging
1983 - Wiley | Contact Dermatitis
Charlotte Menez, Jérémy Coquart, Damien Dodelin, Claire Tourny, Maxime L’Hermette,
Background Mild leg length discrepancy increases biomechanical asymmetry during gait, which leads to low-back pain. Orthotic insoles with a directly integrated heel lift were used to reduce this asymmetry and thus the associated low-back pain. The aim of this study was to analyze the biomechanical adaptations of the locomotor apparatus during gait and the subjective pain ratings before and after the establishment of orthotic insole use. Methods Eight patients with mild leg length discrepancy (≤2.0 ...
Tópico(s): Bone fractures and treatments
2020 - American Podiatric Medical Association | Journal of the American Podiatric Medical Association
Gregory W. Albert, Arnold H. Menezes, Daniel R. Hansen, Jeremy D.W. Greenlee, Stuart L. Weinstein,
Object The authors conducted a study to evaluate the unique presenting signs and symptoms of Chiari malformation Type I (CM-I) in children younger than 6 years of age and highlight the benefits of early surgical treatment in this patient population. Methods The authors reviewed the medical records of patients who presented to the neurosurgery department before their 6th birthday and subsequently underwent surgery for CM-I. They identified 39 patients who had been evaluated between 1984 and 2007 and ...
Tópico(s): Family and Disability Support Research
2010 - | Journal of Neurosurgery Pediatrics
Charlotte Menez, Maxime L’Hermette, Jérémy Coquart,
Background: Mild leg length discrepancy can lead to musculoskeletal disorders; however, the magnitude starting from which leg length discrepancy alters the biomechanics of gait or benefits from treatment interventions is not clear. Research question: The aim of the current study was to examine the immediate effects of orthotic insoles on gait symmetry and pain on mild leg length discrepancy according to two groups of the leg length discrepancy (i.e., LLD ≤ 1 cm vs. LLD > 1 cm). Methods: Forty-six ...
Tópico(s): Lower Extremity Biomechanics and Pathologies
2020 - Frontiers Media | Frontiers in Sports and Active Living
Produção Nacional
Revisado por pares
Patricia Silvia Romano, Takahiko Akematsu, Sébastien Besteiro, Annina Bindschedler, Vern B. Carruthers, Zeinab Chahine, Isabelle Coppens, Albert Descoteaux, Thabata Duque, Cynthia Y. He, Volker T. Heussler, Hervé Le Stunff, Feng‐Jun Li, Juliana Perrone Bezerra de Menezes, Rubem F. S. Menna‐Barreto, Jeremy C. Mottram, Jacqueline Schmuckli‐Maurer, Boris Turk, Patrícia Sampaio Tavares Veras, Betiana Nebaí Salassa, María Cristina Vanrell,
Pathogenic protists are a group of organisms responsible for causing a variety of human diseases including malaria, sleeping sickness, Chagas disease, leishmaniasis, and toxoplasmosis, among others. These diseases, which affect more than one billion people globally, mainly the poorest populations, are characterized by severe chronic stages and the lack of effective antiparasitic treatment. Parasitic protists display complex life-cycles and go through different cellular transformations in order to ...
Tópico(s): Trypanosoma species research and implications
2023 - | Autophagy Reports
Stanley Zammit, Kate Thomas, Andrew Thompson, Jeremy Horwood, Paulo Rossi Menezes, David Gunnell, Chris Hollis, Dieter Wolke, Glyn Lewis, Glynn Harrison,
Background Adverse effects of maternal substance use during pregnancy on fetal development may increase risk of psychopathology. Aims To examine whether maternal use of tobacco, cannabis or alcohol during pregnancy increases risk of offspring psychotic symptoms. Method A longitudinal study of 6356 adolescents, age 12, who completed a semi-structured interview for psychotic symptoms in the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort. Results Frequency of maternal tobacco ...
Tópico(s): Neuroscience of respiration and sleep
2009 - Cambridge University Press | The British Journal of Psychiatry
Produção Nacional
Revisado por pares
Niklas Gericke, Rebecca Bruu Carver, Jérémy Castéra, Neima Alice Menezes Evangelista, Claire Coiffard Marre, Charbel Niño El-Hani,
Genetic determinism can be described as the attribution of the formation of traits to genes, where genes are ascribed more causal power than what scientific consensus suggests. Belief in genetic determinism is an educational problem because it contradicts scientific knowledge, and is a societal problem because it has the potential to foster intolerant attitudes such as racism and prejudice against sexual orientation. In this article, we begin by investigating the very nature of belief in genetic ...
Tópico(s): BRCA gene mutations in cancer
2017 - Springer Science+Business Media | Science & Education
Damien Dodelin, Claire Tourny, Charlotte Menez, Jérémy Coquart, L Hermette M,
Introduction: Foot overpronation is commonly associated with injuries in runners, and may contribute to iliotibial band syndrome, although to date, the effect of overpronation on this injury has been little studied. The aim of this study was to assess the effect of anti-pronation orthotic insoles on pain and hip and knee kinematics in runners with overpronation and iliotibial band syndrome. Case description: Three runners with iliotibial band syndrome underwent repeated kinematic analysis during ...
Tópico(s): Sports Performance and Training
2018 - OMICS Publishing Group | Clinical Research on Foot & Ankle
Jeremy D.W. Greenlee, Arnold H. Menezes, Bryan A. Bertoglio, Kathleen A. Donovan,
Abstract OBJECTIVE: To better understand the presentation, management, and outcome of syringobulbia in the pediatric age group. METHODS: The University of Iowa pediatric neurosurgery database was searched for patients under the age of 18 with a diagnosis of syringobulbia. The patients' records were retrospectively reviewed for demographic data, chief complaint and presenting symptoms, neurological and radiographic findings, treatment, outcome, and complications. Children with open neural tube defects ...
Tópico(s): Head and Neck Surgical Oncology
2005 - Lippincott Williams & Wilkins | Neurosurgery
Albert J. Fenoy, Jeremy D.W. Greenlee, Arnold H. Menezes, Kathleen A. Donovan, Yutaka Satō, Patrick W. Hitchon, John C. Chaloupka,
Object Tumors originating in the vertebrae in children are difficult to treat. In this paper the authors sought to evaluate the decision-making process and outcome of surgical intervention in this population given the complex issues of spinal stability, continued skeletal growth, intraoperative blood loss, and long-term outcome. Methods To select patients for this study, the authors retrospectively reviewed medical records and images at the University of Iowa Hospitals and Clinics between 1996 and ...
Tópico(s): Histiocytic Disorders and Treatments
2006 - | Journal of Neurosurgery Pediatrics
Produção Nacional
Revisado por pares
Rebecca Bruu Carver, Jérémy Castéra, Niklas Gericke, Neima Alice Menezes Evangelista, Charbel Niño El-Hani,
In this paper we present the development and validation a comprehensive questionnaire to assess college students' knowledge about modern genetics and genomics, their belief in genetic determinism, and their attitudes towards applications of modern genetics and genomic-based technologies. Written in everyday language with minimal jargon, the Public Understanding and Attitudes towards Genetics and Genomics (PUGGS) questionnaire is intended for use in research on science education and public understanding ...
Tópico(s): BRCA gene mutations in cancer
2017 - Public Library of Science | PLoS ONE
Robert Breunig, Jeremy Hornby, Scott Stacey, Flávio M. Menezes,
We assemble a database consisting of 52 regulatory decisions made by seven different regulators across five different industries. We examine how the proportion of firms' revenue requirements that were disallowed by the regulator vary by regulator, industry and time. Despite the differences in the implementation of price regulation across industries and across jurisdictions in Australia, outcomes are surprisingly consistent. For example, we show that it is not possible to reject the hypothesis that ...
Tópico(s): Auditing, Earnings Management, Governance
2006 - Wiley | Economic Record
Stanley Zammit, Jeremy Horwood, Andrew Thompson, Kate Thomas, Paulo Rossi Menezes, David Gunnell, Chris Hollis, Dieter Wolke, Glyn Lewis, Glynn Harrison,
Psychosis-like symptoms (PLIKS) occur in about 15% of the population, but it is unclear to what extent PLIKS share aetiological mechanisms in common with those for schizophrenia. We examined whether the presence of PLIKS was associated with a family history of schizophrenia (FH-SCZ), or with advancing paternal age, using data from 6356 children in the ALSPAC birth cohort who participated in a semi-structured PLIKS interview at 12 years of age. We found no evidence of association between FH-SCZ and ...
Tópico(s): Bipolar Disorder and Treatment
2008 - Elsevier BV | Schizophrenia Research
Rudzani Mashau, Susan Meiring, Vanessa Quan, Jeremy Nel, Greg Greene, Andrea Arnaiz García, Colin Menezes, Denasha L. Reddy, Michelle Venter, Sarah Stacey, Matamela Madua, Lia Boretti, Thomas S. Harrison, Graeme Meintjes, Amir Shroufi, Laura Triviño-Duran, John Black, Nelesh P. Govender, Shareef Abrahams, Vanessa Pearce, Masego Moncho, Jeanette Wadula, Motlatji Reratilwe Bonnie Maloba, A A Hoosen, Charl Verwey, Colin Menezes, David Moore, Dina Pombo, Gary Reubenson, Grace Ntlemo, Lauren Richards, Maphoshane Nchabeleng, Merika Tsitsi, Moamokgethi Moshe, Mohammed Y. Said, Molebogeng Kolojane, Lesego Mothibi, Nicolette du Plessis, Rispah Chomba, Teena Thomas, Theunis Avenant, Trusha Nana, Vindana Chibabhai, Adhil Maharj, Douglas Wilson, Fathima Naby, Halima Dawood, Khine Swe Swe-Han, Lisha Sookan, Nomonde Dlamini, Praksha Ramajathan, Prasha Mahabeer, Prathna Bhola, Romola Naidoo, Sumayya Haffejee, Surendra Sirkar, Yeishna Ramkillawan, Ken Hamese, Ngoaka Sibiya, Phetho Mangena, Ruth Lekalakala, Greta Hoyland, Sindi Ntuli, Ebrahim Variava, Ignatius Khantsi, Omphile Mekgoe, Adrian Brink, Elizabeth Prentice, Kessendri Reddy, Andrew Whitelaw, Ebrahim Hoosien, Inge Zietsman, Terry Marshall, Xoliswa Poswa, Chetna Govind, J.A.H. Smit, Keshree Pillay, Sharona Seetharam, Victoria Howell, Catherine Samuel, Marthinus Senekal, Colleen Bamford, Andries Dreyer, Louis Marcus, Warren Lowman, Anne von Gottberg, Anthony M. Smith, Azwifarwi Mathunjwa, Cecilia d'Abreu, Cecilia Miller, Cheryl Cohen, Farzana Ismail, Harry Moultrie, Husna Ismail, Jacqueline Weyer, Jackie Kleynhans, Jennifer Rossouw, John Frean, Joy Ebonwu, Judith Mwansa-Kambafwile, Juno Thomas, Kate Bishop, Kerrigan McCarthy, Liliwe Shuping, Linda de Gouveia, Linda Erasmus, Adrian Puren, Lucille Blumberg, Marshagne Smith, Martha Makgoba, Michelle J. Groome, Mignon du Plessis, Mimmy Ngomane, Mokupi Manaka, Myra Moremi, Nazir Ismail, Neo Legare, Nicola Page, Nombulelo Hoho, Olga Perovic, Phuti Sekwadi, Rindidzani E. Magobo, Ruth Mpembe, Sibongile Walaza, Siyanda Dlamini, Sunnieboy Njikho, Tiisetso Lebaka, Wendy Ngubane,
Background Although flucytosine is a key component of WHO-recommended induction treatment for HIV-associated cryptococcal meningitis, this antifungal agent is not widely available in low-income and middle-income countries due to limited production and cost. In 2018, a national flucytosine access programme was initiated in South Africa. We aimed to determine the effectiveness of flucytosine-containing induction regimens in routine care to motivate for the urgent registration of flucytosine and its ...
Tópico(s): Nail Diseases and Treatments
2022 - Elsevier BV | The Lancet Infectious Diseases
Stanley Zammit, David Odd, Jeremy Horwood, Andrew Thompson, Kyla H Thomas, Paulo Rossi Menezes, David Gunnell, Chris Hollis, Dieter Wolke, Glyn Lewis, Glynn Harrison,
Background Non-clinical psychosis-like symptoms (PLIKS) occur in about 15% of the population. It is not clear whether adverse events during early development alter the risk of developing PLIKS. We aimed to examine whether maternal infection, diabetes or pre-eclampsia during pregnancy, gestational age, perinatal cardiopulmonary resuscitation or 5-min Apgar score were associated with development of psychotic symptoms during early adolescence. Method A longitudinal study of 6356 12-year-old adolescents ...
Tópico(s): Neuroscience of respiration and sleep
2009 - Cambridge University Press | Psychological Medicine
Produção Nacional
Revisado por pares
Thiago Marques Ivaniski, Pedro J. Castro, D. Rodrigues, Jérémy Épp, Rafael Menezes Nunes, Alexandre da Silva Rocha,
Controlling the recrystallization is an important way to reach grain size refinement and outstanding strength and toughness on alloy metals. This study sets out the application and investigation of mathematical microstructure modeling of a newly designed bainitic steel for hot forging industrial applications. The macro-scale model was used to observe and predict the austenitic grain size behavior during the controlled forging of a gear. Arrhenius grain growth kinetic and recrystallization model ...
Tópico(s): Metal Alloys Wear and Properties
2022 - Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímer | Materials Research
Produção Nacional
Revisado por pares
Juan Dong, Jérémy Épp, Alexandre da Silva Rocha, Rafael Menezes Nunes, Hans‐Werner Zoch,
In this study, the distortion of steel shafts was investigated before and after induction hardening. Several essential influencing factors in the manufacturing process chain regarding cold drawing, cutting method, notches on the shafts, and induction hardening were analyzed by design of experiment (DoE). Further necessary examinations of microstructures, hardness profile, segregation of chemical composition, and residual stress state were conducted for understanding the distortion behavior. The results ...
Tópico(s): Metal Alloys Wear and Properties
2015 - Springer Science+Business Media | Metallurgical and Materials Transactions A
Amir Shroufi, Nelesh P. Govender, Graeme Meintjes, John Black, Jeremy Nel, Mahomed‐Yunus S. Moosa, Colin Menezes, Halima Dawood, Douglas Wilson, Laura Triviño Durán, Olawale Ajose, Richard A. Murphy, Thomas S. Harrison, Angela Loyse, Carol Ruffell, Gilles Van Cutsem,
Cryptococcal meningitis (CM) is estimated to cause 181 000 deaths annually, with the majority occurring in Sub-Saharan Africa. Flucytosine is recommended by the World Health Organization as part of the treatment for CM. Widespread use of flucytosine could reduce mortality in hospital by as much as 40% compared to the standard of care, yet due to market failure, quality-assured flucytosine remains unregistered and largely inaccessible throughout Africa.The recently established South African flucytosine ...
Tópico(s): Antifungal resistance and susceptibility
2020 - Elsevier BV | International Journal of Infectious Diseases
Jeremy D.W. Greenlee, Kathleen A. Donovan, David Hasan, Arnold H. Menezes,
Introduction. The entity of hindbrain herniation without myelodysplasia in the very young child has been poorly described. A retrospective analysis of children diagnosed with Chiari I malformation (CM I) before their sixth birthday is presented. Methods. Since 1985, 31 children with CM I (0.3–5.8) years of age have been diagnosed at University of Iowa Hospitals and Clinics. Their records were reviewed for presenting symptoms, signs, radiographic findings, treatment, complications, and outcome. Results. ...
Tópico(s): Family and Disability Support Research
2002 - American Academy of Pediatrics | PEDIATRICS
Jeremy D.W. Greenlee, P. Charles Garell, Nicholas Stence, Arnold H. Menezes,
Chiari malformation is a developmental disorder that is often associated with other abnormalities of the cerebrospinal axis. Despite widespread recognition of this association, there is relatively little information on the treatment of these coexisting disorders in the setting of cerebellar tonsillar ectopia. In an effort to improve the care provided to pediatric patients with Chiari malformations the authors reviewed their management practices over the last 20 years. Specifically, they recorded ...
Tópico(s): Teratomas and Epidermoid Cysts
1999 - American Association of Neurological Surgeons | Neurosurgical FOCUS
Jeremy D.W. Greenlee, Albert J. Fenoy, Kathleen A. Donovan, Arnold H. Menezes,
<i>Background/Aims:</i> Eosinophilic granuloma (EG) involving the vertebrae in the pediatric population presents a difficult management scenario. Issues of surgical versus nonsurgical intervention, spinal stability and continued skeletal growth must all be considered. <i>Methods:</i> A retrospective review of medical records and radiographs from 1964 to the present yielded 12 patients with age less than 18 at the time of diagnosis of primary spinal EG. <i>Results:</i> ...
Tópico(s): Spinal Dysraphism and Malformations
2007 - Karger Publishers | Pediatric Neurosurgery
Eucilene A. Santana-Porto, Adriana A. Oliveira, Marcos Rogério Menezes da Costa, Amiraldo S. Pinheiro, Consuelo Silva de Oliveira, Maria Luiza Diniz de Sousa Lopes, Luiz Eloy Pereira, Cláudio Tavares Sacchi, Wildo Navegantes de Araújo, Jeremy Sobel,
To the Editor: Brazilian purpuric fever (BPF), a Haemophilus aegyptius–caused febrile hemorrhagic illness of children that begins with conjunctivitis and has a case-fatality rate of 40%–90% (1,2), was first recognized during a 1984 outbreak. Before June 2007, 69 cases were reported worldwide; 65 were from Brazil (1–3). To our knowledge, the disease had not been reported in the Amazon region until this investigation, which was precipitated by the report of 5 cases of a compatible syndrome in Anajas, ...
Tópico(s): Viral Infections and Vectors
2009 - Centers for Disease Control and Prevention | Emerging infectious diseases
Sophie Zinn‐Justin, Laurence Pillet, Frédéric Ducancel, Aline Thomas, Jeremy C. Smith, Jean‐Claude Boulain, Andre Ménèz,
Structural features associated with the ability of a monoclonal antibody (mAb) to discriminate between protein variants are identified and engineered. The variants are the curaremimetic toxin α from Naja nigricollis and erabutoxin a or b from Laticauda semifasciata which differ from each other by 16 substitutions and one insertion. The neutralizing mAb Mα1 recognizes with high affinity a topographical epitope on the surface of toxin α, but fails to recognize the erabutoxins although they possess ...
Tópico(s): Toxin Mechanisms and Immunotoxins
1994 - Oxford University Press | Protein Engineering Design and Selection
Philippe Cuniasse, Aline Thomas, Jeremy C. Smith, Hung Lam Thanh, Michel Léonetti, Andre Ménèz,
A synthetic octadecapeptide with the amino acid sequence of residues 23-40 of toxin alpha from Naja nigricollis, cyclized with a disulfide bridge between residues 23 and 40, induces antibodies that cross-react with toxin alpha. We report a structural analysis of this peptide in aqueous solution using NMR spectroscopy and molecular modeling. Structures compatible with the 151 obtained NMR distance restraints were generated using a random simulated annealing protocol followed by restrained high-temperature ...
Tópico(s): T-cell and B-cell Immunology
1995 - American Chemical Society | Biochemistry
Mariko Sato, Jessica A.O. Zimmerman, John M. Buatti, Arnold H. Menezes, Jeremy D.W. Greenlee, Saul Wilson, Brian J. Dlouhy, M. Sue O’Dorisio,
Tópico(s): Vascular Malformations Diagnosis and Treatment
2016 - Oxford University Press | Neuro-Oncology