Éva Fige, Judit Szendrei, László Sós, Izabela Kraszewska, László Potor, József Balla, Zsuzsa Szondy,
Heme oxygenase-1 (HO-1) plays a vital role in the catabolism of heme and yields equimolar amounts of biliverdin, carbon monoxide, and free iron. We report that macrophages engulfing either the low amount of heme-containing apoptotic thymocytes or the high amount of heme-containing eryptotic red blood cells (eRBCs) strongly upregulate HO-1. The induction by apoptotic thymocytes is dependent on soluble signals, which do not include adenylate cyclase activators but induce the p38 mitogen-activated protein ( ...
Tópico(s): Neonatal Health and Biochemistry
2021 - Multidisciplinary Digital Publishing Institute | Cells
Attila Bai, Péter Jobbágy, József Popp, Ferenc Farkaš, Gábor Grasselli, János Szendrei, Péter Balogh,
Tópico(s): Vehicle emissions and performance
2016 - Elsevier BV | Transportation Research Part D Transport and Environment
Dénes Karsai, Rudolf Gesztelyi, Judit Zsuga, Anita Jakab, Levente Szendrei, Béla Juhász, István Bak, Gergo Szabo, István Lekli, Miklós Vecsernyés, E Varga, A. József Szentmiklósi, Árpád Tósaki,
Tópico(s): Nitric Oxide and Endothelin Effects
2007 - Springer Science+Business Media | Cell Biochemistry and Biophysics
Dalma Kurkó, Zsófia Bekes, Anikó Gere, Andrea Baki, András Mihály Boros, Sándor Kolok, Gyula Bugovics, József Nagy, Zsolt Szombathelyi, Györgyi Ignácz-Szendrei,
Adrenergic α1, α2 and β receptors are members of the G-protein-coupled receptor families (GPCRs) mediating physiological responses to adrenaline (epinephrine) and noradrenaline (norepinephrine). Since GPCRs are major targets for potential therapeutic agents, development of robust, reliable and cost effective functional screening methods for these receptors is in the focus of pharmacological research. For this reason, the aim of the present study was to develop an intracellular calcium assay for investigating ...
Tópico(s): Pain Mechanisms and Treatments
2009 - Elsevier BV | Neurochemistry International
István Bak, Levente Szendrei, Tibor Turóczi, Gábor Papp, Ferenc Joó, Dipak K. Das, Joël de Leiris, Péter Dér, Béla Juhász, E Varga, Ildikó Bácskay, József Balla, Péter Kovács, Árpád Tósaki,
Heme oxygenase-1 (HO-1)-dependent carbon monoxide (CO) production related to reperfusion-induced ventricular fibrillation (VF) was studied in HO-1 wild-type (+/+), heterozygous (+/-), and homozygous (-/-) isolated ischemic/reperfused mouse heart. In HO-1 homozygous myocardium, under aerobic conditions, HO-1 enzyme activity, HO-1 mRNA, and protein expression were not detected in comparison with aerobically perfused wild-type and heterozygous myocardium. In wild-type, HO-1 hetero- and homozygous hearts subjected to 20 min ...
Tópico(s): Hemoglobin structure and function
2003 - Wiley | The FASEB Journal
József Fekete, G. Szendrei, M. Csibi,
Some pedological and micromorphological investigations were carried out on representative red clay samples selected from a large number of profiles. On the basis of conclusions drawn from the analytical results, the red clays can be divided into the following groups: - The red clays of the foothills of the Tokaj Mountains were formed on rhyolite or rhyolite tuff, and are covered by loess in some areas. They are relic soils, older than loess, formed under the warm climate of the Tertiary Period. In ...
Tópico(s): Marine and environmental studies
2006 - Akadémiai Kiadó | Agrokémia és Talajtan
Borbála Antal, László Szendrei, Károly Rédei, József Csajbók,
One of the most important method of habitat development is wildlife forage ground management. Many plant species can be grown on the crop fields, as mixture, too. Use of seed mixtures has not been spread on the native wildlife forage ground, however there are many advantages of them. The aim of the research is to examine the role of the different plant species, seed mixtures in the game feeding, the savouriness of the plants of crop fields, as well as ascertain which seed mixtures are more suitable ...
Tópico(s): Environmental and Biological Research in Conflict Zones
2013 - University of Debrecen | Acta Agraria Debreceniensis
Dalma Kurkó, András Mihály Boros, Péter Dezső, Zoltán Urbányi, Miklós Sárvári, József Nagy, Zsolt Szombathelyi, Györgyi I. Szendrei,
Neurofibrillary tangles are composed of insoluble aggregates of microtubule-associated protein Tau. In the pathology of Alzheimer's disease (AD), accumulation of hyperphosphorylated Tau results in formation of paired helical filaments. One of the main candidate to hyperphosphorylate Tau in AD is glycogen synthase kinase 3β (GSK-3β). Here we introduce a non-neuronal cell line, stably co-expressing human Tau and GSK-3β proteins, where the effect of potential kinase inhibitors on Tau phosphorylation ...
Tópico(s): Wnt/β-catenin signaling in development and cancer
2006 - Elsevier BV | Neurochemistry International