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Artigo Brasil Produção Nacional Revisado por pares

Ana Cristina de Medeiros Ribeiro, Lissiane Karine Noronha Guedes, Júlio César Bertacini de Moraes, Carla Gonçalves Schahin Saad, Nádia Emi Aikawa, Ana Luísa Calich, I. L. A. Franca, Jozélio Freire de Carvalho, Percival D. Sampaio‐Barros, Célio Roberto Gonçalves, Eduardo Ferreira Borba, M. d. C. S. Timenetsky, Alexander Roberto Precioso, A Duarte, Eloísa Bonfá, Iêda Maria Magalhães Laurindo,

Background Reduced response to pandemic (2009) H1N1 (pH1N1) vaccine in patients with rheumatoid arthritis (RA) was recently reported. Objectives To evaluate the contribution of age, disease activity, medication and previous antibody levels to this reduced response. Methods 340 adult RA patients and 234 healthy controls were assessed before and 21 days after adjuvant-free influenza A/California/7/2009 (pH1N1) vaccine. Disease activity (DAS28), current treatment and pH1N1 antibody titres were collected. Seroprotection, ...

Tópico(s): vaccines and immunoinformatics approaches

2011 - BMJ | Annals of the Rheumatic Diseases

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Nádia Emi Aikawa, Léonard de Vinci Kanda Kupa, Ana Cristina de Medeiros Ribeiro, Carla Gonçalves Schahin Saad, Emily Figueiredo Neves Yuki, Sandra Gofinet Pasoto, Priscila Tagliaferro Rojo, Rosa Maria Rodrigues Pereira, Samuel Katsuyuki Shinjo, Percival D. Sampaio‐Barros, Danieli Andrade, Ari Stiel Radu Halpern, Ricardo Fuller, Fernando Henrique Carlos de Souza, Lissiane Karine Noronha Guedes, Ana Paula Luppino Assad, Júlio César Bertacini de Moraes, Michelle Remião Ugolini‐Lopes, Victor Adriano de Oliveira Martins, Lorena Betancourt, Carolina Torres Ribeiro, Lucas Peixoto Sales, Isabela Maria Bertoglio, Virgínia Lúcia Nazário Bonoldi, Renata Lys Pinheiro Mello, Gustavo Guimarães Moreira Balbi, Ana Marli Christovam Sartori, Leila Antonângelo, Clóvis A. Silva, Eloísa Bonfá,

Objective To determine the immunogenicity of the third dose of CoronaVac vaccine in a large population of patients with autoimmune rheumatic diseases (ARD) and the factors associated with impaired response. Methods Adult patients with ARD and age-balanced/sex-balanced controls (control group, CG) previously vaccinated with two doses of CoronaVac received the third dose at D210 (6 months after the second dose). The presence of anti-SARS-CoV-2 S1/S2 IgG and neutralising antibodies (NAb) was evaluated ...

Tópico(s): Peripheral Neuropathies and Disorders

2022 - BMJ | Annals of the Rheumatic Diseases

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Guilherme Berto Roça, Ruth Graf, Renato da Silva Freitas, Guataçara Schenfelder Salles, Júlio César Francisco, Lúcia de Noronha, Ivan Maluf,

Capsular contracture (CC) is a common complication after breast augmentation. Autologous fat grafting may be effective for restoring tissue vascularization and function.The authors evaluated the efficacy of autologous fat grafting in a porcine model as a treatment for CC after breast augmentation.This prospective study was performed in 20 female 30-day-old pigs. Each animal was implanted with three 30-cc textured silicone implants (stage 1 of the experiment). Group A served as the untreated control ...

Tópico(s): Tissue Engineering and Regenerative Medicine

2014 - Oxford University Press | Aesthetic Surgery Journal

Artigo Brasil Produção Nacional Revisado por pares

Ana Cristina de Medeiros Ribeiro, Iêda Maria Magalhães Laurindo, Lissiane Karine Noronha Guedes, Carla Gonçalves Schahin Saad, Júlio César Bertacini de Moraes, Clóvis A. Silva, Eloísa Bonfá,

To evaluate the influence of abatacept (ABA) and associated contributing factors on pandemic 2009 influenza A/H1N1 vaccine immunogenicity in rheumatoid arthritis (RA) patients.The response to a nonadjuvanted monovalent pandemic 2009 influenza A/H1N1 killed virus vaccine was analyzed in 11 RA patients using ABA (RA-ABA), most with concomitant nonbiologic disease-modifying antirheumatic drugs (DMARDS), and compared to 33 age-matched RA patients on methotrexate (MTX) and 55 healthy controls, all without ...

Tópico(s): Monoclonal and Polyclonal Antibodies Research

2012 - Wiley | Arthritis Care & Research

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Paulo Ricardo Baggio Simeoni, Rossana Baggio Simeoni, Paulo André Bispo Machado Júnior, Meila Bastos de Almeida, Dilcele Silva Moreira Dziedzic, Nádia Nascimento da Rosa, Priscila Elias Ferreira Stricker, Anna Flávia Ribeiro dos Santos Miggiolaro, Guilherme Naves, Nelson Bergonse Neto, Lúcia de Noronha, Júlio César Francisco, Katherine Athayde Teixeira de Carvalho, Luiz César Guarita-Souza,

Acellular amniotic membrane (AM) has been studied, with promising results on the reconstruction of lesioned tissues, and has become an attractive approach for tracheal repair. This study aimed to evaluate the repair of the trachea with human umbilical cord mesenchymal stem cells (hucMSCs) differentiated in chondrocytes, grown on an experimental model. Tracheal defects were induced by surgical tracheostomy in 30 New Zealand rabbits, and the acellular amniotic membrane, with or without cells, was covering ...

Tópico(s): Trauma Management and Diagnosis

2021 - Multidisciplinary Digital Publishing Institute | Life

Artigo Brasil Produção Nacional Revisado por pares

Thayana Ayres-Alves, Adauto Lima Cardoso, Cleusa Yoshiko Nagamachi, Leandro Melo de Sousa, Júlio César Pieczarka, Renata Coelho Rodrigues Noronha,

Loricariidae family comprises the greatest variability of Neotropical catfish species, with more than 800 valid species. This family shows significant chromosomal diversity. Mapping of repetitive DNA sequences can be very useful in exploring such diversity, especially among groups that appear to share a preserved karyotypic macrostructure. We describe the karyotypes of Panaque armbrusteri and Panaqolus sp., as assessed using classical cytogenetic methods. Moreover, we offer a map of their repetitive ...

Tópico(s): CRISPR and Genetic Engineering

2017 - Mary Ann Liebert, Inc. | Zebrafish

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Kevin Santos da Silva, Larissa Glugoski, Marcelo Ricardo Vicari, Augusto César Paes de Souza, Renata Coelho Rodrigues Noronha, Júlio César Pieczarka, Cleusa Yoshiko Nagamachi,

The Ancistrus genus has extensive chromosomal diversity among species, including heteromorphic sex chromosomes occurrence. However, studies have been shown that chromosomal diversity may still be underestimated. Repetitive sequences represent a large part of eukaryotic genomes, associated with mechanisms of karyotypic diversification, including sex chromosomes evolution. This study analyzed the karyotype diversification of two Ancistrus species (Ancistrus sp. 1 and Ancistrus sp. 2) from the Amazon ...

Tópico(s): Genetic diversity and population structure

2022 - Frontiers Media | Frontiers in Genetics

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Márcia de Noronha Pinho, Renê Donizeti Ribeiro Oliveira, Arthur B. Novaes, Júlio César Voltarelli,

This study analyzed the association of periodontal disease (PD) and rheumatoid arthritis (RA). Seventy-five 35-60-year-old patients were assigned to 5 groups according to the presence (+) or not (-) of PD and RA and the treatment received (TR+) or not (TR-) for PD. Group 3 uses total prosthesis (TP). Clinical and laboratory evaluations were performed at baseline, 3 and 6 months of follow-up by probing pocket depth, bleeding on probing and plaque index for PD, HAQ, DAS28, SF-36 and laboratory: AAG, ESR, CRP for ...

Tópico(s): Oral Health Pathology and Treatment

2009 - Fundação Odontológica de Ribeirão Preto | Brazilian Dental Journal

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Rosangela Alquieri Fedato, Júlio César Francisco, Gabriel Sliva, Lúcia de Noronha, Márcia Olandoski, José Rocha Faria‐Neto, Priscila Elias Ferreira, Rossana Baggio Simeoni, Eltyeb Abdelwahid, Katherine Athayde Teixeira de Carvalho, Luiz César Guarita-Souza,

Achilles tendon pathologies occur frequently and have a significant socioeconomic impact. Currently, there is no evidence on the best treatment for these pathologies. Cell therapy has been studied in several animal models, and encouraging results have been observed with respect to tissue regeneration. This study is aimed at evaluating the functional and histological effects of bone marrow stem cell or platelet-rich plasma implantation compared to eccentric training in the treatment of Achilles tendinopathy ...

Tópico(s): Musculoskeletal synovial abnormalities and treatments

2019 - Hindawi Publishing Corporation | Stem Cells International

Artigo Brasil Produção Nacional Revisado por pares

Lúcia de Noronha, Eduardo Wei Kin Chin, C Menini, José Knopfholz, Júlio César Ribas Rampazzo, Ruth Graf,

In the 1960s, carbon dioxide (CO2) laser therapy started to be applied to eliminate wrinkles, actinic scars, and acne because of its capacity of induce intracellular water vaporization. However, recent studies have shown the efficacy of the erbium laser in removing delicate and moderate scars. Furthermore, the postoperative lesions induced by the erbium laser seem to resolve faster and with less erythematous pattern compared with lesions induced by the CO2 laser. The purpose of this study was to ...

Tópico(s): Facial Rejuvenation and Surgery Techniques

2001 - Lippincott Williams & Wilkins | Plastic & Reconstructive Surgery

Artigo Brasil Produção Nacional Revisado por pares

Renata Coelho Rodrigues Noronha, Cleusa Yoshiko Nagamachi, Júlio César Pieczarka, Suely Aparecida Marques-Aguiar, Regina Maria de Souza Barros,

Abstract Sex-autosome translocations are found in Chiroptera of the Phyllostomidae, leading to multiple XY1Y2 and composite neo-XY systems of chromosomal sex determination. We compared the behaviour of the sex chromosomes of Glossophaga soricina with a simple XX/XY system, Artibeus lituratus and A. obscurus with a multiple XX/XY1Y2 system, A. cinereus and Uroderma magnirostrum with a neo-XX/XY system. In this study we utilized the conventional meiosis, synaptonemic complex and C banding techniques. ...

Tópico(s): Chromosomal and Genetic Variations

2001 - University of Florence | Caryologia

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Eduardo Ferreira Borba, Carla Gonçalves Schahin Saad, Sandra Gofinet Pasoto, Ana Luísa Calich, Nádia Emi Aikawa, Ana Cristina de Medeiros Ribeiro, Júlio César Bertacini de Moraes, Elaine Pires Leon, Leonora Pires Costa, Lissiane Karine Noronha Guedes, Clóvis A. Silva, Célio Roberto Gonçalves, Ricardo Fuller, S. A. Oliveira, María Akíko Ishida, Alexander Roberto Precioso, Eloísa Bonfá,

Objective. To assess the efficacy and safety of pandemic 2009 influenza A (H1N1) in SLE under different therapeutic regimens. Methods. A total of 555 SLE patients and 170 healthy controls were vaccinated with a single dose of a non-adjuvanted preparation. According to current therapy, patients were initially classified as SLE No Therapy ( n = 75) and SLE with Therapy ( n = 480). Subsequent evaluations included groups under monotherapy: chloroquine (CQ) ( n = 105), prednisone (PRED) ≥20 mg ( n = 76), immunosuppressor ( ...

Tópico(s): Monoclonal and Polyclonal Antibodies Research

2012 - Oxford University Press | Lara D. Veeken

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ananda Marques Pety, Adauto Lima Cardoso, Cleusa Yoshiko Nagamachi, Júlio César Pieczarka, Leandro Melo de Sousa, Renata Coelho Rodrigues Noronha,

Loricariidae is a diverse group of fish from the neotropical region, occupying a wide variety of freshwater environments. Cytogenetic data have brought important insights into Loricariidae diversity because they help validate undescribed species as well as our understanding of inter- and intraspecific diversity. However, conventional cytogenetic approaches are limited in their ability to detect variability in some lineages, as seen in the Peckoltia clade, owing to their apparent conserved karyotype. ...

Tópico(s): Genomics and Phylogenetic Studies

2018 - Mary Ann Liebert, Inc. | Zebrafish

Artigo Acesso aberto Revisado por pares

Etiene Faria Aguiar, Rafaella Tonani, Fabiana de Góes Paiola, Michelle Alexandra Chinelatti, Carolina Noronha Ferraz de Arruda, Julio César Souza da Matta, Fernanda de Carvalho Panzeri Pires‐de‐Souza,

Aim: The aim of this study was to evaluate the bond strength of artificial teeth to different types of denture base resins when submitted to thermomechanical cycling (TMC). Methods: Sixty artificial mandibular first molars (Trilux, Vipi) were randomly divided into 3 groups according to denture base acrylic resins (Vipi Wave, Vipi Cril, and Vipi Cril Plus, Vipi). The teeth were fixed onto self-polymerizing acrylic resin bars (0.5 cm2 cross-section x 2 cm height), and the set was included in a metal flask ...

Tópico(s): Dental Research and COVID-19

2018 - UNIVERSIDADE ESTADUAL DE CAMPINAS | Brazilian journal of oral sciences/Brazilian Journal of Oral Sciences

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Renata Coelho Rodrigues Noronha, Cleusa Yoshiko Nagamachi, Júlio César Pieczarka, Suely Aparecida Marques-Aguiar, Maria De Fátima Lima De Assis, Regina Maria de Souza Barros,

Abstract - Meiotic analyses of the sex chromosomes were made in two different species belonging to the subfamily Carollinae (Phyllostomidae, Chiroptera): Rhinophylla pumilio and Carollia perspicillata. These species have different sex chromosome systems. Through banding techniques, chromosomes homologies between Carollia perspicillata and Rhinophylla pumilio were not found, possibly because Carollia species have highly rearranged chromosomes. Probably, Rhinophylla is better associated to Phyllostomini ...

Tópico(s): Hemiptera Insect Studies

2004 - University of Florence | Caryologia

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Kevin Santos da Silva, Augusto César Paes de Souza, Ananda Marques Pety, Renata Coelho Rodrigues Noronha, Marcelo Ricardo Vicari, Júlio César Pieczarka, Cleusa Yoshiko Nagamachi,

Peckoltia is widely distributed genus in the Amazon and Orinoco basins and the Guiana Shield, containing 18 valid species, and distinct morphotypes still needing description in the scientific literature due to its great taxonomic complexity. This study performed a comparative chromosomal analysis of two undescribed Peckoltia species (Peckoltia sp. 3 Jarumã and Peckoltia sp. 4 Caripetuba) from the Brazilian Amazon using conventional chromosome bands methods and in situ localization of the repetitive ...

Tópico(s): Fish Biology and Ecology Studies

2021 - Frontiers Media | Frontiers in Genetics

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Bruno Rafael Ribeiro de Almeida, Susana Suely Rodrigues Milhomem–Paixão, Renata Coelho Rodrigues Noronha, Cleusa Yoshiko Nagamachi, Marlyson Jeremias Rodrigues da Costa, Pedro Pereira de Oliveira Pardal, Johne Souza Coelho, Júlio César Pieczarka,

Holocentric chromosomes occur in approximately 750 species of eukaryotes. Among them, the genus Tityus (Scorpiones, Buthidae) has a labile karyotype that shows complex multivalent associations during male meiosis. Thus, taking advantage of the excellent model provided by the Buthidae scorpions, here we analyzed the chromosomal distribution of several repetitive DNA classes on the holocentric chromosomes of different populations of the species Tityus obscurus Gervais, 1843, highlighting their involvement ...

Tópico(s): Genetic diversity and population structure

2017 - BioMed Central | BMC Genomic Data

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Paulo José Siqueira do Amaral, Cleusa Yoshiko Nagamachi, Renata Coelho Rodrigues Noronha, Marlyson Jeremias Rodrigues da Costa, Adenilson Leão Pereira, Rogério Vieira Rossi, Ana Cristina Mendes de Oliveira, Júlio César Pieczarka,

Abstract Background Proechimys is the most diverse genus in family Echimyidae, comprising 25 species (two of which are polytypic) and 39 taxa. Despite the numerous forms of this rodent and their abundance in nature, there are many taxonomic problems due to phenotypic similarities within the genus and high intraspecific variation. Extensive karyotypic variation has been noted, however, with diploid numbers (2n) ranging from 14 to 62 chromosomes. Some heteromorphism can be found, and 57 different karyotypes ...

Tópico(s): Chromosomal and Genetic Variations

2013 - BioMed Central | BMC Genomic Data

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Aline Luri Takejima, Júlio César Francisco, Rossana Baggio Simeoni, Lúcia de Noronha, Luiz A.F.M. Garbers, Kátia Martins Foltz, Paulo A.B. Machado, Isio Carvalho de Souza, Ricardo A. Pinho, Katherine Athayde Teixeira de Carvalho, Luiz César Guarita-Souza,

Stem cells (SC) and amniotic membrane (AM) are recognized for their beneficial impacts on the healing of cutaneous wounds. Thus, this study evaluated the capacity of tissue repair in a skin lesion rat model. Forty Wistar rats were randomized into four groups: group I – control, with full-thickness lesions on the back, without SC or AM; group II–injected SC; group III – covered by AM; group IV–injected SC and covered by AM. Lesion closure was assessed using contraction rate (Cr). Histochemical and immunohistochemical ...

Tópico(s): Corneal Surgery and Treatments

2021 - Taylor & Francis | Tissue Barriers

Artigo Brasil Produção Nacional Revisado por pares

Adauto Lima Cardoso, Hagi Lopescu Silva Carvalho, Thayse Cristine Melo Benathar, Suellen M. Gales, Cleusa Yoshiko Nagamachi, Júlio César Pieczarka, Leandro Melo de Sousa, Jonathan Stuart Ready, Renata Coelho Rodrigues Noronha,

The diversity of Hypancistrus species in the Xingu River is remarkable and the variation in color morphs represents a real challenge to taxonomists to delimit species boundaries. One of the most recognizable Hypancistrus complexes is the worm-lined species, known in the aquarium trade as King Tiger Plec in English, Hypancistrus "pão" in Portuguese or under the L-numbers L066 and L333 that represent two melanic pigment pattern phenotypes. To assess the identity of these two phenotypes, we described ...

Tópico(s): Ichthyology and Marine Biology

2016 - Mary Ann Liebert, Inc. | Zebrafish

Artigo Brasil Produção Nacional Revisado por pares

Marlyson Jeremias Rodrigues da Costa, Paulo José Siqueira do Amaral, Júlio César Pieczarka, Maria I. C. Sampaio, Rogério Vieira Rossi, Ana Cristina Mendes de Oliveira, Renata Coelho Rodrigues Noronha, Cleusa Yoshiko Nagamachi,

The spiny rats of the genus <i>Proechimys</i> have a wide distribution in the Amazon, covering all areas of endemism of this region. We analyzed the karyotype and cytochrome b <i>(Cyt b)</i> sequences in <i>Proechimys goeldii </i>from 6 localities representing 3 interfluves of the eastern Amazon. A clear separation of <i>P. goeldii</i> into 2 monophyletic clades was observed, both chromosomally and based on <i>Cyt b</i> sequences: cytotype A (2n = 26&#x2640;/27&# ...

Tópico(s): Genetic diversity and population structure

2016 - Karger Publishers | Cytogenetic and Genome Research

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Dilcele Silva Moreira Dziedzic, Júlio César Francisco, Bassam Felipe Mogharbel, Ana Carolina Irioda, Priscila Elias Ferreira Stricker, Juliana Ferreira Floriano, Lúcia de Noronha, Eltyeb Abdelwahid, Célia Regina Cavichiolo Franco, Katherine Athayde Teixeira de Carvalho,

Discarded tissues, like human amniotic membranes and adipose tissue, were investigated for the application of Decellularized Human Amniotic Membrane (DAM) as a viable scaffold for transplantation of Adipose-derived stromal cells (ASCs) in bone regeneration of non-healing calvarial defects in rats. Amniotic membrane was decellularized to provide a scaffold for male Wistar rats ASCs expansion and transplantation. ASCs osteoinduction in vitro promoted the deposition of a mineralized bone-like matrix ...

Tópico(s): Periodontal Regeneration and Treatments

2021 - Springer Science+Business Media | Calcified Tissue International

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gustavo Gavazzoni Blume, Paulo André Bispo Machado Júnior, Rossana Baggio Simeoni, Giovana Paludo Bertinato, Murilo Sgarbossa Tonial, Seigo Nagashima, Ricardo A. Pinho, Lúcia de Noronha, Márcia Olandoski, Katherine Athayde Teixeira de Carvalho, Júlio César Francisco, Luiz César Guarita-Souza,

Myocardial infarction (MI) remains the leading cause of cardiovascular death worldwide and a major cause of heart failure. Recent studies have suggested that cell-based therapies with bone marrow stem cells (BMSC) and human amniotic membrane (hAM) would recover the ventricular function after MI; however, the mechanisms underlying these effects are still controversial. Herein, we aimed to compare the effects of BMSC and hAM in a rat model of heart failure. MI was induced through coronary occlusion, ...

Tópico(s): Mesenchymal stem cell research

2021 - Multidisciplinary Digital Publishing Institute | Life

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Renata Coelho Rodrigues Noronha, L. M. R. Barros, Ramon Everton Ferreira de Araújo, Diego Ferreira Marques, Cleusa Yoshiko Nagamachi, Cesar Martins, Júlio César Pieczarka,

Cytogenetic studies were conducted in the Brazilian Amazon turtles, Podocnemis expansa Schweigger, 1912 (PEX) and Podocnemis unifilis Troschel, 1848 (PUN) to understand their karyoevolution. Their chromosomal complements were compared using banding techniques (C, G-, Ag-NOR and Chromomycin A3) and fluorescence in situ hybridization (FISH), and efforts were made to establish evolutionary chromosomal relationships within the Podocnemidae family.Our results revealed that both species have a chromosome ...

Tópico(s): Turtle Biology and Conservation

2016 - BioMed Central | Molecular Cytogenetics

Artigo Brasil Produção Nacional Revisado por pares

Frederico Heloui de Araujo, Fernando Augusto de Noronha Castro Pinto, Julio Cesar Boscher Torres,

Beamforming algorithms are widely used nowadays to localize sound sources in several types of environments. In general, the goal is to identify the direction from where a given signal is arriving. It consists of a spatial analysis performed over 2D maps, according to the frequency bands of interest or to a given spectral characteristic. In this paper, a spherical microphone array structure is developed. The signals obtained are input to Wavelet transform, in order to decompose impulse responses ...

Tópico(s): Acoustic Wave Phenomena Research

2017 - Elsevier BV | Applied Acoustics

Artigo Brasil Produção Nacional Revisado por pares

Carla Gonçalves Schahin Saad, Eduardo Ferreira Borba, Nádia Emi Aikawa, Clóvis A. Silva, Rosa Maria Rodrigues Pereira, Ana Luísa Calich, Júlio César Bertacini de Moraes, Ana Cristina de Medeiros Ribeiro, Víctor Viana, Sandra Gofinet Pasoto, Jozélio Freire de Carvalho, I. L. A. Franca, Lissiane Karine Noronha Guedes, Samuel Katsuyuki Shinjo, Percival D. Sampaio‐Barros, M. T. C. Caleiro, Célio Roberto Gonçalves, Ricardo Fuller, Maurício Levy‐Neto, María do Carmo Sampaio Tavares Timenetsky, Alexander Roberto Precioso, Eloísa Bonfá,

Background Despite the WHO recommendation that the 2010–2011 trivalent seasonal flu vaccine must contain A/California/7/2009/H1N1-like virus there is no consistent data regarding its immunogenicity and safety in a large autoimmune rheumatic disease (ARD) population. Methods 1668 ARD patients (systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), ankylosing spondylitis (AS), systemic sclerosis, psoriatic arthritis (PsA), Behçet's disease (BD), mixed connective tissue disease, primary antiphospholipid ...

Tópico(s): Rheumatoid Arthritis Research and Therapies

2011 - BMJ | Annals of the Rheumatic Diseases

Artigo Brasil Produção Nacional Revisado por pares

William Kondo, Eduardo Andreazza Dal Lago, Júlio César Francisco, Rossana Baggio Simeoni, Lúcia de Noronha, Ana Paula Camargo Martins, Marina Luise Viola de Azevedo, Carolina Chaves Ferreira, Priscila Maestrelli, Márcia Olandoski, Luiz César Guarita-Souza, Vivian Ferreira do Amaral,

Objective To study the effect of bone marrow derived-mononuclear stem cells transplantation in the growth, VEGF-R and TNF-alpha expression of surgically induced endometriosis in an experimental model. Study design This is an experimental study conducted in the Center for Health and Biological Sciences at the Pontifical Catholic University of Parana, Brazil. Endometriotic implants were surgically induced in 120 female Wistar rats. The animals with viable endometrial implant (larger than 25 mm2) were ...

Tópico(s): Uterine Myomas and Treatments

2011 - Elsevier BV | European Journal of Obstetrics & Gynecology and Reproductive Biology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Renata Coelho Rodrigues Noronha, Bruno Rafael Ribeiro de Almeida, Marlyson Jeremias Rodrigues da Costa, Cleusa Yoshiko Nagamachi, Cesar Martins, Júlio César Pieczarka,

Abstract Heterozygous chromosomal rearrangements can result in failures during the meiotic cycle and the apoptosis of germline, making carrier individuals infertile. The Amazon frog Leptodactylus pentadactylus has a meiotic multivalent, composed of 12 sex chromosomes. The mechanisms by which this multi-chromosome system maintains fertility in males of this species remain undetermined. In this study we investigated the meiotic behavior of this multivalent to understand how synapse, recombination ...

Tópico(s): Genetic diversity and population structure

2020 - Nature Portfolio | Scientific Reports