Olaia Bronte, Francisco Javier González‐Barcala, Xavier Muñoz, Ana Pueyo-Bastida, Jacinto Ramos‐González, Isabel Urrutia-Landa,
Asthma is the most common chronic respiratory disease and a major public health problem. Although the causal relationship between air pollution and asthma remains controversial, a large number of studies have provided increasingly consistent evidence of the involvement of air pollutants in asthma onset and exacerbations. We conducted a keyword search-based literature review using PubMed, Scopus and Web of Science databases for studies with titles or abstracts containing predefined terms. This narrative ...
Tópico(s): Air Quality Monitoring and Forecasting
2023 - Elsevier BV | Open Respiratory Archives
Christian Domingo, T. Carrillo Díaz, Marina Blanco–Aparicio, Eva Martínez Moragón, D Bañas Conejero, María Guadalupe Sánchez Herrero, Mariana Muñoz, Héctor Cabrerizo, Antonio Valero, Ebymar Arismendi, Irina Bobolea, Gemma López, Celia Pinedo, Francisco Javier González‐Barcala, Purificación Pérez-López-Corona, Jacinto Ramos‐González, Javier Martín-Puentes, Gregorio Soto-Campos, Francisco Pérez-Grimaldi, Inmaculada Lluch, Juan Luis García‐Rivero, Celia Gutierrez-Villegas, Idoia Salinas-Garrido, Cleofé Fernández-Aracil, Luís Puente‐Maestu, Walther Iván Girón, Ángela Gómez-Sacristán, Miguel Díaz-Palacios, Ethel Ibáñez-Echevarría, Irene De Lorenzo, Ana Sogo, Daniel Ross-Monserrate, Elena Prina, Eusebi Chiner‐Vives, Sandra Vañes, Rocío Magdalena Díaz-Campos, Ismael García‐Moguel, Carmen Montero, María Fernández-Marrube, Tamara Hermida-Valverde, Anaís Enríquez, Núria Marina-Malanda, Ana Gómez-Larrauri, Antonio García-Dumpiérrez, Rodolfo Castillo-Sainz, Nancy Ortega, Lourdes Almeida, Luis Cabanes, Santiago Quirce, Javier Domínguez‐Ortega, David Romero, Irene Hernández, Daniel Laorden, Carolina Cisneros, Antolín López-Viña, Andrea Trisán, Teresa Caruana-Careaga, Ana Gόmez-Bastero, Lucía Marín-Barrera,
The efficacy of mepolizumab is well documented in severe eosinophilic asthma (SEA), although the stringent selection criteria adopted by SEA clinical trials limits the generalizability of results. Our study evaluated the effectiveness and safety of mepolizumab in patients with SEA in Spain. The primary efficacy endpoint was the change in the rate of clinically significant asthma exacerbations 12 months after starting mepolizumab compared to the baseline rate in the 12 months prior to treatment. Patients ...
Tópico(s): Respiratory and Cough-Related Research
2021 - Adis, Springer Healthcare | Drugs
Tim Harrison, Pascal Chanez, Francesco Menzella, Giorgio Walter Canonica, Renaud Louis, Borja G. Cosío, Njira Lugogo, Arjun Mohan, Annie Burden, Lawrence McDermott, Esther Garcia Gil, James Zangrilli, Wolfgang Pohl, Robert Voves, Maud Deschampheleire, Renaud Louis, Jean‐Benoît Martinot, Rudi Peché, Kenneth R. Chapman, Amarjit Cheema, Delbert R. Dorscheid, J. Mark FitzGerald, Rémi Gagnon, William Patrick Killorn, Ronald Olivenstein, George Philteos, Clare D. Ramsey, Julia Rolf, Brandie Walker, Ole Hilberg, Tina Skjold, Ingrid Louise Titlestad, Auli Hakulinen, Maritta Kilpeläinen, M. Ben Hayoun, Philippe Bonniaud, Arnaud Bourdin, Pascal Chanez, Frédéric de Blay, Gaëtan Deslée, Gilles Devouassoux, A. Didier, Y. Douadi, Stéphanie Fry, Gilles Garcia, Pierre‐Olivier Girodet, Christophe Leroyer, A. Magnan, Guillaume Mahay, C. Nocent, Christophe Pison, Pauline-Marie Roux, Camille Taillé, Juliana-Angelica Tiotiu, Ekkehard Beck, Margret Jandl, Christian Kaehler, Frank F Käßner, Frank Koesters, Juliane Kronsbein, Thomas Schaum, Christian Schulz, Dirk Skowasch, Christian Taube, Tobias Welte, A de Roux, Bianca Beghè, Francesco Blasi, Giorgio Walter Canonica, Giovanna Elisiana Carpagnano, Cristiano Caruso, Angelo Guido Corsico, Elio Constantino, Nunzio Crimi, Piero Maestrelli, Francesco Menzella, Manlio Milanese, Alberto Papi, Girolamo Pelaia, Laura Pini, Pierachille Santus, Eleonora Savi, Nicola Scichilone, Gianenrico Senna, Giuseppe Spadaro, Adriano Vaghi, Steven Gans, Jurgen Hölters, Bas Langeveld, Willem R. Pieters, Gerald Staaks, Ilonka van Veen, Jan Willem van den Berg, Gunnar Einvik, Sverre Lehmann, Ismael Ali García, Carlos Almonacid, Irina Bobolea, Paloma Campo Mozo, Gustavo de Luiz, Christian Domingo, José María Echave-Sustaeta María-Tomé, Juan Luis García‐Rivero, Borja G. Cosío, A. Gómez-Bastero Fernández, Ruperto González‐Pérez, Aythamy Henríquez Santa, Carlos Martínez‐Rivera, Xavier Muñoz, Jacinto Ramos, José Gregorio Soto Campos, Carmen Vidal Pan, Nikolai Stenfors, Alf Tunsäter, Ines Vinge, Rekha Chaudhuri, Timothy Harrison, Adel Mansur, Shuaib Nasser, Monica Nordstrom, Paul Pfeffer, Dinesh Saralaya, Philip Short, Arun Adlakha, Oral Alpan, Francis Averill, Anil Badhwar, Jose Bardelas, Barbara D. Baxter, George Bensch, William Berger, Jonathan A. Bernstein, Tracy Bridges, Ryan Brimeyer, William J. Calhoun, Edward J. Campbell, W. Brett Cherry, Geoffrey Chupp, Lee Clore, John R. Cohn, Jeremy Cole, John J. Condemi, James Cury, Benjamin Davis, Samuel DeLeon, Luis DeLaCruz, Joseph D. Diaz, David Erb, Emeka Eziri, Faisal Fakih, Douglas Fiedler, David A. Fost, Stephen B. Fritz, E. González González, Brad Goodman, Peter A. Gottlieb, Gregory Gottschlich, Richard Gower, Rizan Hajal, James B. Harris, Hengameh Heidarian-Raissy, Albrecht Heyder, David A. Hill, Fernando Holguín, Iftikhar Hussain, Jonathan Illowite, Joshua Jacobs, Mikell Jarratt, Harold B. Kaiser, Neil L. Kao, Ravindra Kashyap, David Kaufman, Edward Kent, Kenneth Kim, Ryan Klein, Monica Kraft, Ritsu Kono, Shahrukh Kureishy, Jeffrey Leflein, Mila A. Leong, Huamin Li, Robert Y. Lin, Njira Lugogo, Michael Marcus, Diego Jose Maselli Caceres, Vinay Mehta, Curtis J. Mello, Mark Millard, Aaron P. Milstone, Arjun Mohan, Wendy C. Moore, Mark Moss, N. Mumneh, Thomas D. O’Brien, David Ostransky, Michael Palumbo, Purvi Parikh, Sudhir Parikh, Amit Patel, Guido O. Pérez, W PLESKOW, Bruce M. Prenner, Dileep Puppala, John Ramey, Joan Reibman, Ramón López de los Reyes, Emory Robinette, Ileana Rodicio, Stephen Ryan, Sudhir Sekhsaria, Barry Sigal, Vinay Sikand, Weily Soong, Selwyn Spangenthal, Roy St. John, Gary C. Steven, Vijay Subramaniam, Kaharu Sumino, Eric Sztejman, Ricardo Tan, Tonny Tanus, Charles S. Thompson, Carl E. Thornblade, Manuel Villareal, Sally E. Wenzel, Heidi Zafra, Tomasz M. Ziedalski,
Background ANDHI was done to assess the efficacy of benralizumab, including onset of effect and impact on health-related quality of life (HRQOL), exacerbation rate, lung function, and nasal polyposis symptoms. Methods This phase 3b, randomised, double-blind, parallel-group, placebo-controlled ANDHI study was completed in adults (aged 18–75 years) with severe eosinophilic asthma with at least 2 exacerbations in the previous year, despite high-dose inhaled corticosteroid plus additional controllers, ...
Tópico(s): Pediatric health and respiratory diseases
2020 - Elsevier BV | The Lancet Respiratory Medicine
Luís Pérez de Llano, Eva Martínez-Moragón, Vicente Plaza, Andrea Trisan Alonso, Carlos Almonacid Sánchez, Francisco Javier Callejas, Elisabeth Vera, José Gregorio Soto Campos, Carlos Martínez‐Rivera, Bernardino Alcázar Navarrete, Isabel Urrutia Landa, Juan Luis García‐Rivero, Alicia Padilla, Francisco Javier Álvarez Gutiérrez, Pedro Landete, Jacinto Ramos González, Cleofé Fernández Aracil, J. Gracia, Inmaculada Lluch, Luís Puente‐Maestu, Rubén Andújar Espinosa, Borja G. Cosío,
-We have added the following highlights:•It seems reasonable to approach asthma heterogeneity pragmatically, setting specific therapeutic goals for each individual and associating them with treatable traits.•The most common clinical phenotype was late-onset eosinophilic asthma (58.1%) in a population of adult uncontrolled severe asthmatics.•More than half of the patients had not experienced severe exacerbations in the previous year and the most common therapeutic objective was symptom control (71% ...
Tópico(s): Chronic Obstructive Pulmonary Disease (COPD) Research
2019 - Elsevier BV | Respiratory Medicine
Luís Pérez de Llano, Juan Luis García‐Rivero, Isabel Urrutia, Eva Martínez‐Moragón, Jacinto Ramos, Pilar Cebollero, Francisco Carballada, Marina Blanco–Aparicio, María del Carmen Vennera, María Merino, Yolanda Torralba, Vicente Plaza,
The minimum controlling dose of treatment must be established in patients with asthma, but the outcome of step-down is unpredictable.To identify factors associated with risk of control loss when stepping down asthma treatment and to develop a score to predict this risk.A prospective, multicenter study including adults with well-controlled asthma was performed. Treatment was stepped up or stepped down over a 12-month period to maintain asthma control. We determined associations between clinical and ...
Tópico(s): Inhalation and Respiratory Drug Delivery
2018 - Elsevier BV | The Journal of Allergy and Clinical Immunology In Practice
Juliana Maria de Sousa Pinto, Ana María Martín Nogueras, J.I. Calvo-Arenillas, Jacinto Ramos‐González,
In Brief PURPOSE: To evaluate the benefits of home-based pulmonary rehabilitation (PR) in patients with severe and very severe chronic obstructive pulmonary disease (COPD). METHODS: Randomized clinical trial involving 58 patients. Pulmonary function, quality of life evaluated by the Saint George Respiratory Questionnaire, breathlessness evaluated by the London Chest Activity of Daily Living Scale, and exercise tolerance evaluated by 6-minute walk distance were assessed at baseline and at 12 weeks. ...
Tópico(s): Cardiac Health and Mental Health
2014 - Lippincott Williams & Wilkins | Journal of Cardiopulmonary Rehabilitation and Prevention
Nuria M. Novoa, Gonzálo Varela, Marcelo F. Jiménez, Jacinto Ramos,
Objectives: Maximum oxygen consumption per min (VO2max) is currently considered the most accurate test for the preoperative risk assessment in patients scheduled for pulmonary resection. Due to its high-technology requirements and cost, VO2max is performed less frequently than is desired. The objective of this investigation is to determine if the measurement of the basal daily ambulatory activity of the patients, with a pedometer, can be used to predict VO2max values. Methods: This is a prospective ...
Tópico(s): Cardiovascular and exercise physiology
2010 - Oxford University Press | European Journal of Cardio-Thoracic Surgery
J.M. González, F.J. de Castro, M. Barrueco, Rosa Cordovilla, José Luis Fernández, F. Gómez, B. Moreno de Vega, Jacinto Ramos, Álvarez Serrano,
Estudio de los factores clínicos y demográficos asociados a las demoras diagnósticas del cáncer de pulmón(CP). Estudio prospectivo de dos años de evolución de pacientes ingresados en la planta de neumología por sospecha de CP. Se estudiaron variables demográficas, de atención sanitaria, hábitat y demoras en las exploraciones. Se definieron los tiempos diagnósticos siguientes: de consulta (desde el primer síntoma hasta la visita del primer médico), medio (el que va desde la visita médica hasta el in- ...
Tópico(s): Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
2003 - Elsevier BV | Archivos de Bronconeumología
Joan B. Soriano, Aurelio Tobı́as, Manolis Kogevinas, Jordi Sunyer, Miguel A. Sáez, Jesús Martínez-Moratalla, Jacinto Ramos, J.A. Maldonado, F. Payo, J. M. Antó,
The relative importance of specific immunoresponse in explaining nonspecific bronchial responsiveness (BR) has scarcely been examined. We provide quantitative estimates of the proportion of BR attributable to specific atopy to different common aeroallergens. We used data from a cross-sectional study on a random sample of the general population 20 to 44 yr of age from five Spanish areas. There were 1,816 participants who performed a methacholine challenge and had atopy assessed. BR was defined as ...
Tópico(s): Respiratory and Cough-Related Research
1996 - American Thoracic Society | American Journal of Respiratory and Critical Care Medicine
Miguel Blanco, Jorge Blanco, Jesús E. Blanco, Jacinto Ramos,
To assess the role of enterotoxigenic (ETEC), verotoxigenic (VTEC), and necrotoxigenic (NTEC) Escherichia coli in cattle with diarrhea, 1,524 colonies of E coli isolated from 197 calves with diarrhea and from 112 healthy controls were investigated for production of heat-labile and heat-stable enterotoxins, verotoxins, and cytotoxic necrotizing factors (CNF1 and CNF2). The ETEC were isolated from only 2 (1%) calves with diarrhea and from 5 (4%) healthy controls. In contrast, VTEC and NTEC that produced ...
Tópico(s): Enterobacteriaceae and Cronobacter Research
1993 - American Veterinary Medical Association | American Journal of Veterinary Research
Amparo Sánchez, Alan R. Schwartz, Pedro L. Sánchez, José Luis Fernández, Jacinto Ramos, Francisco Martín‐Herrero, Rafael González-Celador, Ricardo Ruano, Irene Bregón, Cándido Martín‐Luengo, Francisco Pleite Gómez,
Investigamos los factores del síndrome de apneas-hipopneas durante el sueño (SAHS) que activan los mecanismos de riesgo cardiovascular, a través del estudio de las concentraciones plasmáticas del fragmento N-terminal del precursor del péptido natriurético cerebral (NTproBNP) y de la proteína C reactiva de alta sensibilidad (PCRas), así como el efecto que sobre ellos tiene el tratamiento con presión positiva continua de la vía aérea nasal (CPAPn). Se estudió a 42 pacientes con SAHS (leve-moderado en 15 ...
Tópico(s): Cardiovascular and Diving-Related Complications
2008 - Elsevier BV | Archivos de Bronconeumología
Nuria M. Novoa, Jacinto Ramos, Marcelo F. Jiménez, José María González‐Ruiz, Gonzálo Varela,
Cuantificar el grado de cumplimiento de las recomendaciones contenidas en la guía en la práctica clínica publicada en 2009 por la ERS y la ESTS sobre evaluación preoperatoria del riesgo de la resección pulmonar en la actividad asistencial diaria de un hospital terciario. Estudio prospectivo observacional. Registro de datos en tiempo real de los pacientes consecutivos remitidos para evaluación desde septiembre de 2009 a diciembre de 2010. Se ha registrado la presencia o ausencia de los estudios incluidos ...
Tópico(s): Pleural and Pulmonary Diseases
2012 - Elsevier BV | Archivos de Bronconeumología
Jacinto Ramos González, R. Garza, Roberto Martínez‐Beamonte, Lara Ruíz Gómez,
El cáncer de próstata es una enfermedad que se presenta frecuentemente. A pesar de eso, la presencia de metástasis al pene son muy raras. Sólo se han descrito en la literatura 98 casos hasta el 2003. Presentamos el caso de un paciente con nódulos metastáticos en pene indoloros secundarios a cáncer de próstata. Prostate cancer is a disease that appears with a very high frequency. However, the presence of metastasis to the penis is rare. Only 98 cases reported in the literature up to 2003. We present ...
Tópico(s): Medical Malpractice and Liability Issues
2006 - Elsevier BV | Actas Urológicas Españolas
Sandra Elena-Pérez, D.H. Heredero Jung, Asunción Garcı́a-Sánchez, Miguel Estravís, Maria J. Martin, Jacinto Ramos‐González, Juan Carlos Triviño, María Isidoro‐García, Catalina Sanz, Ignacio Dávila,
Background: Asthma is a heterogeneous syndrome with a broad clinical spectrum and high drug response variability. The inflammatory response in asthma involves multiple effector cells and mediator molecules. Based on asthma immunopathogenesis, precision medicine can be a promising strategy for identifying biomarkers. Biologic therapies acting on the IL-5/IL-5 receptor axis have been developed. IL-5 promotes proliferation, differentiation and activation of eosinophils by binding to the IL-5 receptor, ...
Tópico(s): IL-33, ST2, and ILC Pathways
2021 - Frontiers Media | Frontiers in Medicine
Nuria M. Novoa, Jacinto Ramos, Marcelo F. Jiménez, José María González‐Ruiz, Gonzálo Varela,
To quantify the degree of compliance with the recommendations of the clinical practice guidelines published in 2009 by the ERS and the ESTS regarding the preoperative assessment of risk of lung resection in daily clinical practice at a tertiary hospital. A prospective, observational study of real-time data collected from consecutive patients who had been referred for evaluation from September 2009 to December 2010. We recorded the presence or absence of the recommended studies included in the algorithm, ...
Tópico(s): Clinical practice guidelines implementation
2012 - Elsevier BV | Archivos de Bronconeumología
Renaud Louis, Tim Harrison, Pascal Chanez, Francesco Menzella, George Philteos, Borja G. Cosío, Njira Lugogo, Gustavo de Luiz, Annie Burden, Timothy Adlington, N. Keeling, Justin Kwiatek, Esther Garcia Gil, Wolfgang Pohl, Daniel Doberer, Jean Benoît Martinot, Maud Deschampheleire, Ulrike Himpe, Kenneth R. Chapman, Amarjit Cheema, Delbert R. Dorscheid, Clare D. Ramsey, Jeffrey Rolf, Brandie Walker, Ronald Olivenstein, Claude Poirier, Pierre Larivée, Anne Sofie Bjerrum, Ingrid Louise Titlestad, Ole Hilberg, Maritta Kilpeläinen, Philippe Bonniaud, Camille Taillé, Iuliana-Angelica Tiotiu, Pierre‐Olivier Girodet, F.–X. Blanc, J. Pradelli, A. Didier, Cecilia Nocent Ejnaini, Gaëtan Deslée, Christophe Pison, Y. Douadi, Guillaume Mahay, Gilles Devouassoux, B. Melloni, Pauline-Marie Roux, Arnaud Bourdin, Stéphanie Fry, Thomas Schaum, Christof Schulz, Dirk Skowasch, Christian Taube, Tobias Welte, Wolfgang Gleiber, Randolf Brehler, Jens Schreiber, Wolfgang Schuette, Juliane Kronsbein, R. Bonnet, Ekkehard Beck, Donato Lacedonia, Gianenrico Senna, Cristiano Caruso, Nunzio Crimi, Francesco Blasi, Pierachille Santus, Giorgio Walter Canonica, Gabriella Guarnieri, Girolamo Pelaia, Manlio Milanese, Claudio Micheletto, Angelo Guido Corsico, Nicola Scichilone, Giuseppe Spadaro, Bas Langeveld, Jurgen Holters, Jan Willem van den Berg, Arthur A. J. Smit, Lennart Conemans, Helena van Veen, Gerald Staaks, Sverre Lehmann, José Maria Echave-Sustaeta, Christian Domingo, Gustavo de Luíz Martinez, Ruperto González‐Pérez, Juan Luis García‐Rivero, Xavier Muñoz, José Gregorio Soto Campos, Paloma Campo Mozo, Carmen Vidal Pan, A. Gómez-Bastero Fernández, Sergio Campos Tellez, Carlos Martínez‐Rivera, Irina Bobolea, Raquel Morillo Guerrero, Ismael Ali García, Juan Luis Rodríguez Hermosa, Nikolai Stenfors, Alf Tunsäter, Dan Curiac, Christophe von Garnier, Jörg D. Leuppi, Peter Schmid‐Grendelmeier, Shuaib Nasser, Rekha Chaudhuri, Monica Nordstrom, Dinesh Saralaya, Paul Pfeffer, Adel Mansur, Philip Short, Sally E. Wenzel, W. Brett Cherry, Heidi Zafra, E. González González, Weily Soong, Benjamin G. Davis, Neil L. Kao, Iftikhar Hussain, Diego Jose Maselli Caceres, James B. Harris, William J. Calhoun, Ileana Rodicio, David Kaufman, Mark B. Moss, Eric Sztejman, Samuel DeLeon, Kaharu Sumino, Ravindra Kashyap, Jeffrey Leflein, Rizan Hajal, Faisal Fakih, David Hill, Robert P. Lin, Mikell Jarratt, Vijay Subramaniam, Robert W. Sussman, N. Mumneh, Joan Reibman, Jared I. Darveaux, Ricardo Tan, Tonny Tanus, Vinay Sikand, Gailen D. Marshall, Hemalini Mehta, Jeremy Cole, Brad Goodman, Deborah Goss, Jose Bardelas, Aaron M. Milstone, Vinay Mehta, Lee Clore, Mark Millard, Michael Palumbo, Dileep Puppala, Mila A. Leong, Bruce M. Prenner, Emory Robinette, Hengameh Heidarian Raissy, David A. Fost, W PLESKOW, Michael B. Marcus, Jonathan Ilowite, Wendy C. Moore, G. Steven, Luis de la Cruz‐Merino, Geoffrey Chupp, William Berger, Christopher Randolph, Fernando Holguín, Shahrukh Kureishy, Edward M. Campbell, Rudi Peché, Laura Pini, Alberto Papi, Bianca Beghè, Silvia Peveri, Aythamy Henríquez Santa, Jacinto Ramos González, Ines Vinge, Roy St. John,
The phase IIIb, randomized, parallel-group, placebo-controlled ANDHI double-blind (DB) study extended understanding of the efficacy of benralizumab for patients with severe eosinophilic asthma. Patients from ANDHI DB could join the 56-week ANDHI in Practice (IP) single-arm, open-label extension substudy.Assess potential for standard-of-care background medication reductions while maintaining asthma control with benralizumab.Following ANDHI DB completion, eligible adults were enrolled in ANDHI IP. After ...
Tópico(s): Inhalation and Respiratory Drug Delivery
2023 - Elsevier BV | The Journal of Allergy and Clinical Immunology In Practice
Asunción Garcı́a-Sánchez, Miguel Estravís, Maria J. Martin, Jacqueline Pérez‐Pazos, Cristina Martín, María Gil‐Melcón, Jacinto Ramos‐González, Ibon Eguíluz‐Gracia, Juan Carlos Triviño, María Isidoro‐García, Ignacio Dávila, Catalina Sanz,
Background: Precision medicine is a promising strategy to identify biomarkers, stratify asthmatic patients according to different endotypes, and match them with the appropriate therapy. This proof-of-concept study aimed to investigate whether gene expression in peripheral blood could provide a valuable noninvasive approach for the molecular phenotyping of asthma. Methods: We performed whole-transcriptome RNA sequencing on peripheral blood of 30 non-atopic non-asthmatic controls and 30 asthmatic ...
Tópico(s): Chronic Obstructive Pulmonary Disease (COPD) Research
2021 - Multidisciplinary Digital Publishing Institute | Journal of Personalized Medicine
Amparo Sánchez, Alan R. Schwartz, Pedro L. Sánchez, José Luis Fernández, Jacinto Ramos, Francisco Martín‐Herrero, Rafael González-Celador, Ricardo Ruano, Irene Bregón, Cándido Martín‐Luengo, Francisco Pleite Gómez,
In this study, we assessed factors associated with cardiovascular risk in patients with sleep apnea-hypopnea syndrome (SAHS) through analysis of plasma concentrations of N-terminal prohormone brain natriuretic peptide (NTproBNP) and high-sensitivity C-reactive protein (hsCRP). In addition, we analyzed the effect of nasal continuous positive airway pressure (nCPAP) on these markers.Forty-two patients with SAHS (mild to moderate in 15 cases and severe in 27) were compared with 14 individuals without SAHS. ...
Tópico(s): Neuroscience of respiration and sleep
2008 - Elsevier BV | Archivos de Bronconeumología
Mamede de Carvalho, Jorge Jacinto, Natália Ramos, Victor De Oliveira, Teresa Pinho e Melo, João de Sá,
Tópico(s): Neuroscience and Neuropharmacology Research
1998 - Springer Science+Business Media | Journal of Neurology
Produção Nacional
Revisado por pares
Juliana Maria de Sousa Pinto, Jacinto Ramos González, José Ignácio Calvo Arenillas, Ana María Martín Nogueras, Francisco Pedro Gómez Gómez,
To compare the effects of asthma and chronic obstructive pulmonary disease (COPD) on the quality of life of patients evaluated using the Saint George Respiratory Questionnaire (SGRQ) through correlating the variables, domains and total score. A cross-sectional study from October 2008 to March 2009 with 75 adult outpatients at the University Hospital of Salamanca, Spain. Patients provided their clinical and socio-demographical data after being informed of the study's aims and ethical aspects. The packa ...
Tópico(s): Health, psychology, and well-being
2010 - Elsevier BV | Revista Portuguesa de Pneumologia
R.A. Medina López, Jacinto Ramos, Belén Congregado Ruiz, Jorge Mariscal, E Sánchez Gómez,
For the not frequent, we contributed a new case of infection urinary produced by the I generate Kluyvera. We make a bibliographical review, clinical expression of the same and we insisted in a series of peculiarities, you like the appearance give because of the treatment pharmacologic and their intestinals.
Tópico(s): Enterobacteriaceae and Cronobacter Research
2001 - Elsevier BV | Actas Urológicas Españolas
Mónica Báñez-Coronel, Ana de Molina, Agustı́n Rodrı́guez-González, Jacinto Sarmentero, Ma Ramos, Miguel Ángel García‐Cabezas, Lourdes Garcia-Oroz, Juan Carlos Lacal,
Choline Kinase (ChoK) comprises a family of cytosolic enzymes involved in the synthesis of phosphatidylcholine (PC), the most abundant phospholipid in eukaryotic cell membranes. One of the ChoK isoforms, Choline Kinase α (ChoKα), is found over expressed in human tumours. Chemical inhibitors able to interfere with ChoK activity have proven to be effective antitumoral drugs in vitro and in vivo. To validate the use of selective ChoKα inhibitors in cancer therapy, we have developed a genetic strategy ...
Tópico(s): Cancer Research and Treatments
2008 - Bentham Science Publishers | Current Cancer Drug Targets
Luis Pérez de Llano, Eva Martínez Moragón, Luis Manuel Entrenas Costa, Carlos Martínez‐Rivera, Carolina Cisneros, Marina Blanco–Aparicio, Andrea Trisán, Vicente Plaza, Jacinto Ramos, E Funenga Fitas, Joaquín Sánchez-Covisa, Javier Domínguez‐Ortega,
Tópico(s): Asthma and respiratory diseases
2022 - ESMON Publicidad | Journal of Investigational Allergology and Clinical Immunology
Miguel Estravís, Jacqueline Pérez‐Pazos, Maria J. Martin, Jacinto Ramos‐González, María Gil‐Melcón, Cristina Martín, Asunción Garcı́a-Sánchez, Catalina Sanz, Ignacio Dávila,
Tópico(s): Respiratory and Cough-Related Research
2022 - Elsevier BV | The Journal of Allergy and Clinical Immunology In Practice
Carlos Almonacid, Carlos Melero Moreno, Antolín López-Viña, Carolina Cisneros, Luis Pérez de Llano, Vicente Plaza, Juan Luis García-Rivero, Auxiliadora Romero Falcön, Jacinto Ramos, Teresa Bazús González, María Andrés Prado, Alfonso Muriel,
Background Poor adherence to inhaled medication in asthma patients is of great concern. It is one of the main reasons for inadequate asthma control. Objective The goal of the research was to determine if motivational messages using short message service (SMS, or text) improved adherence to inhaled medication in patients with asthma. Methods A prospective multicenter randomized parallel-group clinical trial was conducted in 10 asthma clinics in Spain. Adherence was assessed with electronic monitors ( ...
Tópico(s): Medication Adherence and Compliance
2020 - | JMIR Formative Research
Nuria M. Novoa, Marcelo F. Jiménez, José Luis Aranda, Manuel Rodríguez, Jacinto Ramos, María Teresa Gómez-Hernández, Gonzálo Varela,
We hypothesized that postoperative cardiorespiratory morbidity and/or 30-day death rates decreased after implementing the new European ERS/ESTS guidelines for functional evaluation before lung resection and tested the hypothesis by means of a case–control study. The analysis included a series of 916 consecutive patients who underwent an anatomical pulmonary resection for non-small-cell lung cancer in our centre. Patients were divided into cases (September 2009–August 2012) and controls (December 2002– ...
Tópico(s): Chronic Obstructive Pulmonary Disease (COPD) Research
2014 - Oxford University Press | European Journal of Cardio-Thoracic Surgery
Produção Nacional
Revisado por pares
Juliana Maria de Sousa Pinto, Jacinto Ramos González, José Ignácio Calvo Arenillas, Ana María Martín Nogueras, Francisco Pedro Gómez Gómez,
Objectivos: Comparar os efeitos da asma e da DPOC na qualidade de vida dos doentes avaliados pelo Saint George Respiratory Questionnaire (SGRQ) através de correlações entre as variáveis e os domínios e a pontuação total. Métodos: Estudo transversal entre Outubro de 2008 a Março de 2009 com 75 adultos das consultas de ambulatório do Hospital Universitário de Salamanca, Espanha. Depois de informar os objectivos do estudo e os aspectos éticos, foi preenchido um formulário com os dados clínicos e sociodemográficos ...
Tópico(s): Respiratory Support and Mechanisms
2010 - Elsevier BV | Revista Portuguesa de Pneumologia
Christian Domingo, T. Carrillo Díaz, Marina Blanco–Aparicio, Eva Martínez Moragón, D Bañas Conejero, María Guadalupe Sánchez Herrero, Mariana Muñoz, Héctor Cabrerizo, Antonio Valero, Ebymar Arismendi, Irina Bobolea, Gemma López, Celia Pinedo, Francisco Javier González‐Barcala, Purificación Pérez-López-Carona, Jacinto Ramos‐González, Javier Martín-Puentes, Gregorio Soto-Campos, Francisco Pérez-Grimaldi, Inmaculada Lluch, Juan Luis García‐Rivero, Celia Gutierrez-Villegas, Idoia Salinas-Garrido, Cleofé Fernández-Aracil, Luís Puente‐Maestu, Walther Iván Girón, Ángela Gómez-Sacristán, Miguel Díaz-Palacios, Ethel Ibáñez-Echevarría, Irene De Lorenzo, Ana Sogo, Daniel Ross-Monserrate, Elena Prina, Eusebi Chiner‐Vives, Sandra Vañes, Rocío Magdalena Díaz-Campos, Ismael García‐Moguel, Carmen Montero, María Fernández-Marrube, Tamara Hermida-Valverde, Anaís Enríquez, Núria Marina-Malanda, Ana Gómez-Larrauri, Antonio García-Dumpiérrez, Rodolfo Castillo-Sainz, Nancy Ortega, Lourdes Almeida, Luis Cabanes, Santiago Quirce, Javier Domínguez‐Ortega, David Romero, Irene Hernández, Daniel Laorden, Carolina Cisneros, Antolín López-Viña, Andrea Trisán, Teresa Caruana-Careaga, Ana Gόmez-Bastero, Lucía Marín-Barrera,
Tópico(s): Asthma and respiratory diseases
2021 - Adis, Springer Healthcare | Drugs
Maria del Carmen Vargas Fajardo, Nuria M. Novoa, Marcelo F. Jiménez, Jacinto Ramos González, Gonzálo Varela,
Objectives: The aims of this study were to design a best fit linear regression model to estimate VO 2max (estimated VO 2 ) and to compare the ability of VO 2 values (measured and estimated) predicting cardiorespiratory complications in a series of patients undergoing lung resection for lung cancer. Method: This was a prospective, observational study performed in 83 patients. Variables analyzed were: demographic characteristics, comorbidity, body mass index (BMI), FEV1%, FVC%, diffusion capacity (DLCO%), ...
Tópico(s): Delphi Technique in Research
2014 - Elsevier BV | Archivos de Bronconeumología
Francesc Fatjó, Jacinto Ramos, Alexandre Culla, J. M. Grau,
Tópico(s): Central Venous Catheters and Hemodialysis
2002 - Elsevier BV | Medicina Clínica