Robert Jäckie, Oliver Himmler,
This paper complements previous studies on the effects of health on wages by addressing the problems of unobserved heterogeneity, sample selection, and endogeneity in one comprehensive framework. Using data from the German Socio-Economic Panel (GSOEP), we find the health variable to suffer from measurement error and a number of tests provide evidence that selection corrections are necessary. Good health leads to higher wages for men, while there appears to be no significant effect for women. Contingent ...
Tópico(s): Retirement, Disability, and Employment
2010 - University of Wisconsin Press | The Journal of Human Resources
Liliána Szabó, Celeste McCracken, Jackie Cooper, Oliver J. Rider, Hajnalka Vágó, Béla Merkely, Nicholas C. Harvey, Stefan Neubauer, Steffen E. Petersen, Zahra Raisi‐Estabragh,
Abstract Aims We examined associations of obesity with incident cardiovascular outcomes and cardiovascular magnetic resonance (CMR) phenotypes, integrating information from body mass index (BMI) and waist-to-hip ratio (WHR). Then, we used multiple mediation to define the role of obesity-related cardiac remodelling in driving obesity-outcome associations, independent of cardiometabolic diseases. Methods and results In 491 606 UK Biobank participants, using Cox proportional hazard models, greater obesity ( ...
Tópico(s): Cardiovascular Health and Disease Prevention
2023 - Oxford University Press | European Heart Journal - Cardiovascular Imaging
Drew Capone, Aaron Bivins, Jackie Knee, Oliver Cumming, Rassul Nalá, Joe Brown,
Rigorous studies of water, sanitation, and hygiene interventions in low- and middle-income countries (LMICs) suggest that children are exposed to enteric pathogens via multiple interacting pathways, including soil ingestion. In 30 compounds (household clusters) in low-income urban Maputo, Mozambique, we cultured Escherichia coli and quantified gene targets from soils (E. coli: ybbW, Shigella/enteroinvasive E. coli (EIEC): ipaH, Giardia duodenalis: β-giardin) using droplet digital PCR at three compound ...
Tópico(s): Viral gastroenteritis research and epidemiology
2021 - American Chemical Society | Environmental Science & Technology
Bethan Carter, C. Verity Bennett, Hywel Jones, Jackie Bethel, Oliver Perra, Ting Wang, Alison Kemp,
Aim To link routinely collected health data to a cerebral palsy (CP) register in order to enable analysis of healthcare use by severity of CP. Method The Northern Ireland Cerebral Palsy Register was linked to hospital data. Data for those on the CP register born between 1st January 1981 and 31st December 2009 and alive in 2004 were extracted, forming a CP cohort ( n =1684; 57% males, 43% females; aged 0–24y). Frequencies of healthcare events, and the reasons for them, were reported according to CP severity ...
Tópico(s): Infant Development and Preterm Care
2020 - Wiley | Developmental Medicine & Child Neurology
David G. Cox, Jacques Simard, Daniel Sinnett, Yosr Hamdi, Penny Soucy, Manon Ouimet, Laure Barjhoux, Carole Verny-Pierre, Lesley McGuffog, Sue Healey, Csilla I. Szabo, Mark H. Greene, L. Phuong, Irene L. Andrulis, Mads Thomassen, Anne–Marie Gerdes, Maria A. Caligo, Eitan Friedman, Yael Laitman, Bella Kaufman, Shani Shimon Paluch, Åke Borg, Per Karlsson, Marie Stenmark Askmalm, Gisela Barbany Bustinza, Katherine L. Nathanson, Susan M. Domchek, Timothy R. Rebbeck, Javier Benı́tez, Ute Hamann, Matti A. Rookus, Ans M.W. van den Ouweland, Margreet G.E.M. Ausems, Cora M. Aalfs, Christi J. van Asperen, Peter Devilee, Hans J. J. P. Gille, Susan Peock, Debra Frost, D. Gareth Evans, Rosalind A. Eeles, Louise Izatt, Julian Adlard, Joan Paterson, Jacqueline Eason, Andrew K. Godwin, Marie-Alice Remon, Virginie Moncoutier, Marion Gauthier‐Villars, Christine Lasset, Sophie Giraud, Agnès Hardouin, Pascaline Berthet, Hagay Sobol, François Eisinger, Brigitte Bressac–de Paillerets, Olivier Caron, Capucine Delnatte, David E. Goldgar, Alex Miron, Hilmi Özçelik, Saundra S. Buys, Melissa C. Southey, Mary Beth Terry, Christian F. Singer, Anne-Catharina Dressler, Muy‐Kheng M. Tea, Thomas van Overeem Hansen, Óskar Þór Jóhannsson, Marion Piedmonte, Gustavo C. Rodriguez, Jack Basil, Stephanie V. Blank, Amanda E. Toland, Marco Montagna, Claudine Isaacs, Ignacio Blanco, Simon A. Gayther, Kirsten B. Moysich, Rita K. Schmutzler, Barbara Wappenschmidt, Christoph Engel, Alfons Meindl, Nina Ditsch, Norbert Arnold, Dieter Niederacher, Christian Sutter, Dorothea Gadzicki, Britta Fiebig, Miguel de la Hoya, Rachel Laframboise, Heli Nevanlinna, Xiaohong Chen, Jonathan Beesley, Amanda B. Spurdle, Susan L. Neuhausen, Yuan Chun Ding, Fergus J. Couch, Xianshu Wang, Paolo Peterlongo, Siranoush Manoukian, Loris Bernard, Paolo Radice, Douglas F. Easton, Georgia Chenevix‐Trench, Antonis C. Antoniou, Dominique Stoppa‐Lyonnet, Sylvie Mazoyer, Olga M. Sinilnikova, Martine Dumont, Phuong Mai, MH Greene, Gord Glendon, Teresa Selander, Nayana Weerasooriya, Per Karlsson, Margareta Nordling, Annika Bergman, Zakaria Einbeigi, Marie Stenmark-Askmalm, S Liedgren, Åke Borg, Niklas Loman, Håkan Olsson, Ulf Kristoffersson, Maria Soller, Helena Jernström, Katja Harbst, Karin Henriksson, Annika Lindblom, Brita Arver, Anna von Wachenfeldt, Annelie Liljegren, Gisela Barbany, Johanna Rantala, Beatrice Melin, Henrik Grönberg, Eva‐Lena Stattin, Monica Emanuelsson, Hans Ehrencrona, Diana Torres, Muhammad Usman Rashid, Antje Seidel‐Renkert, Frans B.L. Hogervorst, S. Verhoef, Martijn Verheus, Laura J. vanʼt Veer, Flora E. van Leeuwen, Matti A. Rookus, Margriet Collée, A.M.W. van den Ouweland, Agnes Jager, Maartje J. Hooning, Madeleine M.A. Tilanus‐Linthorst, Caroline Seynaeve, Christi J. van Asperen, Juul Wijnen, Maaike P.G. Vreeswijk, R.A. Tollenaar, Peter Devilee, Marjolijn J. L. Ligtenberg, Nicoline Hoogerbrugge, Margreet G.E.M. Ausems, Rob B. van der Luijt, Cora M. Aalfs, T. A. van Os, Gilles Thomas, Quinten Waisfisz, Hanne Meijers‐Heijboer, E. Gómez, Cees E. Van Roozendaal, Marinus J. Blok, BA Caanen, Jan C. Oosterwijk, Annemarie H. van der Hout, M J E Mourits, Hans F. A. Vasen, Douglas F. Easton, Susan Peock, Margaret Cook, Debra Frost, Radka Platte, Zosia Miedzybrodzka, Helen Gregory, Patrick J. Morrison, Lisa Jeffers, T Cole, Kai-Ren Ong, Jonathan Hoffman, Alan Donaldson, Margaret James, Joan Paterson, Sarah Downing, Amy Taylor, Alexandra Murray, Mark T. Rogers, Emma McCann, Esther M. John, David Barton, Mary Porteous, Sarah Drummond, Carole Brewer, Emma Kivuva, Anne Searle, Selina Goodman, Kathryn Hill, Rosemarie Davidson, Victoria Murday, Nicola Bradshaw, Lesley Snadden, Mark Longmuir, Catherine Watt, S. Gibson, Eshika Haque, Edward S. Tobias, Alexis E. Duncan, Louise Izatt, Chris Jacobs, Caroline Langman, Anna Whaite, Huw Dorkins, Julian Barwell, Julian Adlard, Carol Chu, Julie Miller, Ian O. Ellis, Catherine Houghton, D. Gareth Evans, Fiona Lalloo, Jane Taylor, Lucy Side, Alison Male, Cheryl Berlin, Jacqueline Eason, Rebecca Collier, Fiona Douglas, Oonagh Claber, Irene Jobson, Lisa Walker, Diane M. McLeod, Dorothy Halliday, Sarah Durell, Barbara Stayner, Rosalind A. Eeles, Susan Shanley, Nazneen Rahman, Richard S. Houlston, Elizabeth Bancroft, Lucia D’Mello, Elizabeth Page, Audrey Ardern‐Jones, Kelly Kohut, Jennifer Wiggins, Elena Castro, Anita Mitra, Lisa Robertson, Jackie Cook, Oliver Quarrell, Cathryn Bardsley, Shirley Hodgson, Sheila Goff, Glen Brice, Lizzie Winchester, Charlotte Eddy, Vishakha Tripathi, Virginia Attard, Diana Eccles, Anneke Lucassen, Gillian Crawford, Donna McBride, Sarah Smalley, D. Gareth Evans, Fiona Lalloo, Rosalind A. Eeles, Elizabeth Bancroft, Lucia D’Mello, Olga M. Sinilnikova, Laure Barjhoux, Carole Verny-Pierre, Sophie Giraud, Mélanie Léone, Sylvie Mazoyer, Dominique Stoppa‐Lyonnet, Marion Gauthier-Villars, Bruno Buecher, Claude Houdayer, Virginie Moncoutier, Muriel Belotti, Carole Tirapo, Antoine de Pauw, Brigitte Bressac–de Paillerets, Audrey Remenieras, Véronique Byrde, Olivier Caron, Gilbert Lenoir, Yves‐Jean Bignon,
Mutations in the BRCA1 gene substantially increase a woman's lifetime risk of breast cancer. However, there is great variation in this increase in risk with several genetic and non-genetic modifiers identified. The BRCA1 protein plays a central role in DNA repair, a mechanism that is particularly instrumental in safeguarding cells against tumorigenesis. We hypothesized that polymorphisms that alter the expression and/or function of BRCA1 carried on the wild-type (non-mutated) copy of the BRCA1 gene ...
Oxford University Press
Jackie Craissati, Oliver Sindall,
This study examined 94 serious further offences (SFOs) committed by offenders managed by the London Probation Area over a 14-month period between 2004 and 2006. Data was collated on background and criminogenic variables for the sample, as well as retrospectively administering a range of validated actuarial measures of risk prediction. The predictive validity of key variables embedded within the probation OASys tool were also examined, specifically the utility of the DSPD variables and the OGRS and ...
Tópico(s): Criminal Justice and Corrections Analysis
2009 - SAGE Publishing | Probation Journal
Pradeep Vasudevan, Stephen R.F. Twigg, John B. Mulliken, Jackie Cook, Oliver Quarrell, Andrew O.M. Wilkie,
Craniofrontonasal syndrome (CFNS, MIM 304110) is an X-linked craniofacial disorder that shows paradoxically greater severity in heterozygous females than in hemizygous males. Mutations have been identified in the EFNB1 gene that encodes a member of the ephrin-B family of transmembrane ligands for Eph receptor tyrosine kinases. Here, we describe two unrelated families, in both of which a mother and her son have proven mutations in EFNB1. The mothers have classical features of CFNS; although the sons ...
Tópico(s): Wnt/β-catenin signaling in development and cancer
2006 - Springer Nature | European Journal of Human Genetics
Mohamed Aquit, Wolfgang Kuhnt, Ann Holbourn, El Hassane Chellaı̈, Jackie A. Lees, Oliver Kluth, Haddou Jabour,
Research Article| January 01, 2017 Complete archive of late Turonian to early Campanian sedimentary deposition in newly drilled cores from the Tarfaya Basin, SW Morocco Mohamed Aquit; Mohamed Aquit 1Institute of Geosciences, Christian-Albrechts-University of Kiel, 24118 Kiel, Germany Search for other works by this author on: GSW Google Scholar Wolfgang Kuhnt; Wolfgang Kuhnt † 1Institute of Geosciences, Christian-Albrechts-University of Kiel, 24118 Kiel, Germany †wk@gpi.uni-kiel.de Search for other ...
Tópico(s): Geochemistry and Elemental Analysis
2016 - Geological Society of America | Geological Society of America Bulletin
Adrian Hornby, Jackie E. Kendrick, Oliver D. Lamb, Takehiro Hirose, Silvio De Angelis, Felix W. von Aulock, Kodo Umakoshi, Takahiro Miwa, Sarah Henton De Angelis, Fabian B. Wadsworth, Kai‐Uwe Hess, Donald B. Dingwell, Yan Lavallée,
Abstract The concluding episode of activity during the recent eruption of Mt. Unzen (October 1994 to February 1995) was characterized by incremental spine extrusion, accompanied by seismicity. Analysis of the seismic record reveals the occurrence of two dominant long‐period event families associated with a repeating, nondestructive source mechanism, which we attribute to magma failure and fault‐controlled ascent. We obtain constraints on the slip rate and distance of faulting events within these ...
Tópico(s): High-pressure geophysics and materials
2015 - Wiley | Journal of Geophysical Research Solid Earth
Chris Parker, Noel W. Clarke, Adrian Cook, Howard Kynaston, Charles Catton, William Cross, René Horsleben Petersen, Raj Persad, Fred Saad, Lorna C Bower, John Logue, Heather Payne, Silvia Forcat, Cindy Goldstein, Claire Murphy, J R Anderson, Maroie Barkati, David Bottomley, Jennifer Mary Rose Branagan, Ananya Choudhury, Peter Chung, Lyn Cogley, Chee Goh, Peter Hoskin, Vincent Khoo, Shawn Malone, Lindsey Masters, Stephen Morris, Abdenour Nabid, A. Ong, Rakesh Raman, Kathryn Tarver, Alison Tree, Jane Worlding, James Wylie, Anjali Zarkar, Wendy R. Parulekar, Mahesh Parmar, Matthew R. Sydes, Claire Amos, Katherine E. Beaney, Katharine Bellenger, Christopher D. Brawley, Christina Chung, Adrian Cook, Andrew Embleton-Thirsk, Silvia Forcat, Cindy Goldstein, Jenna Grabey, Dominic Hague, Anna Herasimtschuk, Zaheer Islam, Gordana Jovic, C. Maniatis, Lindsey Masters, Fatima Mohamed, Rachel C. Morgan, Claire Murphy, Dipa Noor, Max Parmar, Paul R. Patterson, Holly Pickering, Cheryl Pugh, Mary Rauchenberger, Helena Ribeiro, Carol Roach, Fatimah Seray-Wurie, Preetha Shaji, Hannah Sims, Ben Spittle, Matthew R. Sydes, Nancy Tappenden, Lilian Tsang, Barbara Uscinska, Teddy Brown, Sue Casey, Cathy N. Davidson, Conor Dellar, Mandy Fletcher, Ralph M. Meyer, Karen Murphy, Wendy R. Parulekar, Harriet Richardson, K. Martin Richardson, Kate Whelan, Donald Bissett, Shelagh Bonner-Shand, Judith Grant, Rory Lynch, Graham MacDonald, Marie McWilliam, Rachel Moir, Sue Rodwell, Kirsty Shearer, Margaret Smith, Louise Binns, Maxine Briggs, Simon Brown, Nathalie Casanova, Katy M. Clark, Jasmine Hartley, Ann Henry, Helen Henson, Philip Hill, Ganesan Jeyasanger, Judy McAlister, Sharron Parkinson, Alison Shaw, C. J. Alcock, Joanne E. Brady, Philip Camilleri, Janice Carpenter, Emma Hogbin, Katherine Hyde, Roisin Kavanagh, Alice Ngumo, Cheryl Padilla-Harris, N. Panakis, Thinn Pwint, Ami Sabharwal, Tracey Stammers, Helena Stone, Gail Varley, Andrew Weaver, Hazel Wynn, Elaine Allan, Jawaher Ansari, Philip Cannon, Ross Carruthers, Claudia Coubrough, Chloe Cowan, Hilary Glen, Janet Graham, Maryon Hardie, Clare J. Love, Nicholas MacLeod, Rana Mahmood, Jane McClements, Brian McGlynn, Margaret McKernan, N. Niall McLeod, Aqilah Othman, Kristy Ross, Patricia Roxburgh, Maureen Templeton, Adnan Tufail, Claudia Turley, Mark Wilson, Zulfiqer Ali, Kelly S. Andrews, Rebecca Burns, Caryl Butterworth, Thomas Coventry, Angela D. Evans, Gareth Jones, Sion Lewis, Nikhil Babu Oommen, S. E. Owen, Wendy Saxton, Sister Hayley Tapping, Dianne Thomas, Rachel Thomas, Beth Ann Walker, Rachel Williams, Susan Collard, Victoria Ford, Frances Goodhind, Becky Holbrook, Elizabeth Kershaw, Samantha Ley, Maria C. Martinez, Anne McCormack, Denise Sheehan, Elizabeth Toy, Lynne Van-Koutrik, Mohini Varughese, Katherine Aitken, David J. Barlow, Louise Beattie, Godfrey Bownie-Mukumbu, Rachel Bryan, Victoria Corner, Abigail Edwards, Adrienn Fazekasne Fulep, Teresa Guerrero Urbano, Julie Gwilt, Liz Happle, Dee Jackman, Beata Krysta, Sangeeta Paisey, Richard Shaffer, Jackie Smith, Rosalyne Westley, Hilawati Yusof, Rowan Appleby, Joanne Avis, Mark Beresford, Ruth Brydon-Hill, Christine Cox, Samantha Curtis, Christine Elwell, Olivera Frim, Beatrice Hamilton, Zoe Hudson, A. Jenner, Mark Mantle, Jessica Mason, Susan Masson, Jonathan McFarlane, H Newman, Abigail Pocock, Bryony Robertson, E. Tomlinson, Rebecca Wassall, Sister Tania Williams, Grace Brown, Peter Clarke, Aiden Cole, Jane Cousins, Gail Gilchrist, Chris Hagan, Emma Hanna, J. Harney, Stacey Hetherington, Fionnuala Houghton, S. Hynds, Suneil Jain, R. Johnston, Patrick F. Keane, C. Lyons, J. McAleese, Jo McAllister, Karen McKenna, D. Mitchell, Stacey Murray, Joe M. O’Sullivan, Nambi Rajan, Poh Lin Shum, D.P. Stewart, S. Stranex, Grace Totten, Madhura Chandrashekara, Ellen Drew, Mary Drew, Julie Fletcher, Tina Gamble, Rachel Lokes, Ann Schumacher, Kavitha Shetty, Sundip Sohanpal, James Whitehouse, Anjali Zarkar, Daniel Ford, J. Glaholm, Daniel Lenton, Rachael O'Beney, Sundip Sohanpal, H.F. Taylor, Helen Thomas, James Whitehouse, Samantha Chetiyawardana, Alissa N. Doherty, A. El-Modir, Daniel Ford, J. Glaholm, Melanie Gunn, Nicholas D. James, L Kedge, Rachel Lokes, Aliyah Mannan, Josephine Marange, Andrew P. Morrison, Maryanne Okubanjo, Darlletta Olaniyi-Oduntan, Zhane Peterkin, George Preece, Zayn Qureshi, Liliam Ross, Tarandip Samra, Elizabeth Southgate, Rebekah Stephens, Robert Stevenson, Phillip Watson-Jones, Anjali Zarkar, Danya Abdulwahid, Sarah Ainsworth, Sue Ashworth, Karen Stansberry Beard, Natalie Charnley, Parth Desai, Bethany Fielding, Jan Flaherty, Diane Forrest, Helen Frankland, Imran Haidar, Jeanette Hargreaves,
Previous evidence indicates that adjuvant, short-course androgen deprivation therapy (ADT) improves metastasis-free survival when given with primary radiotherapy for intermediate-risk and high-risk localised prostate cancer. However, the value of ADT with postoperative radiotherapy after radical prostatectomy is unclear.
Elsevier BV
Elizabeth Ford, Nicholas Greenslade, Priyamvada Paudyal, Stephen Bremner, Helen Smith, Sube Banerjee, Shanu Sadhwani, Philip Rooney, Seb Oliver, Jackie Cassell,
Possible dementia is usually identified in primary care by general practitioners (GPs) who refer to specialists for diagnosis. Only two-thirds of dementia cases are currently recorded in primary care, so increasing the proportion of cases diagnosed is a strategic priority for the UK and internationally. Variables in the primary care record may indicate risk of developing dementia, and could be combined in a predictive model to help find patients who are missing a diagnosis. We conducted a meta-analysis ...
Tópico(s): Geriatric Care and Nursing Homes
2018 - Public Library of Science | PLoS ONE
Jane A. McKeating, C Shotton, S. A. Jeffs, Christopher P. Palmer, Anthea L. Hammond, Julie Lewis, KATHRYN C. OLIVER, Jackie May, Peter Balfe,
We have monitored the immunogenicity of a V1V2 sub-fragment of gp120 in contrast to the full length protein and to a truncated form (PR12) where the V1, V2 and V3 regions were removed. In contrast to previously published work [1] these studies show that monomeric forms of envelope are capable of inducing antibodies specific for both linear and discontinuous epitopes. These antibodies are capable of neutralising HIV infectivity. The majority of neutrolising antibodies were specific for epitopes within ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
1996 - Elsevier BV | Immunology Letters
Daniel A. Gittins, Pierre‐Arnaud Desiage, Natasha Morrison, Jayne E. Rattray, Srijak Bhatnagar, Anirban Chakraborty, Jackie Zorz, Carmen Li, Oliver Horanszky, Margaret A. Cramm, Francesco Bisiach, R Bennett, Jamie Webb, Adam MacDonald, Martin G. Fowler, D C Campbell, Casey R. J. Hubert,
The deep biosphere is the largest microbial habitat on Earth and features abundant bacterial endospores. Whereas dormancy and survival at theoretical energy minima are hallmarks of microbial physiology in the subsurface, ecological processes such as dispersal and selection in the deep biosphere remain poorly understood. We investigated the biogeography of dispersing bacteria in the deep sea where upward hydrocarbon seepage was confirmed by acoustic imagery and geochemistry. Thermophilic endospores ...
Tópico(s): Genomics and Phylogenetic Studies
2022 - American Association for the Advancement of Science | Science Advances
Merle Sowman, Jackie Sunde, Serge Raemaekers, Oliver John Schultz,
With the advent of democracy in South Africa there were great expectations that poor coastal fishing communities would gain legal access to coastal resources historically relied on for food and livelihoods. However, a failure to formally recognise the small-scale fisheries sector and adequately cater for them in the post 1994 law reform process, precipitated legal action by a group of fishers against the Minister (George K and others vs. the Minister of Environmental Affairs and Tourism) in 2005. ...
Tópico(s): Sex work and related issues
2014 - Elsevier BV | Marine Policy
Emma C. Roper, A. A. M. Gibson, Mark E. McAlindon, Lyda Williams, Jackie Cook, Rosalind Kandler, Oliver Quarrell,
Abstract Familial visceral neuropathy (FVN) is a heterogeneous group of disorders due to abnormalities of the myenteric plexus. FVN with neuronal intranuclear inclusions is one particular form of FVN with a variable phenotype that includes achalasia, gastro‐esophageal reflux, intestinal dysmotility and pseudo‐obstruction, dysarthria, peripheral neuropathy and pupillary defects, and the presence of intranuclear inclusions within the neurons of the enteric nervous system. We present a four‐generation ...
Tópico(s): Eosinophilic Esophagitis
2005 - Wiley | American Journal of Medical Genetics Part A
Denise Howel, Colin Fischbacher, Raj Bhopal, Jackie Gray, Jane Metcalf, Oliver James,
Primary biliary cirrhosis (PBC) is a disease of unknown etiology, with unexplained geographical variation. Various exposures have been suggested as triggers for disease development—possibly in susceptible individuals, but the evidence was not always well founded. We therefore conducted a population-based case-control study in Northeast England to investigate these and other exposures. All cases incident during 1993 to 1995 in a defined area of Northeast England were identified, and age- and sex-matched ...
Tópico(s): Liver Disease and Transplantation
2000 - Lippincott Williams & Wilkins | Hepatology
Drew Capone, David Berendes, Oliver Cumming, Jackie Knee, Rassul Nalá, Benjamin B. Risk, Christine Stauber, Kevin Zhu, Joe Brown,
Sewage surveillance is increasingly used in public health applications; metabolites, biomarkers, and pathogens are detectable in wastewater and can provide useful information about community health. Work on this topic has been limited to wastewaters in mainly high-income settings, however. In low-income countries, where the burden of enteric infection is high, nonsewered sanitation predominates. In order to assess the utility of fecal sludge surveillance as a tool to identify the most prevalent ...
Tópico(s): Fecal contamination and water quality
2020 - American Chemical Society | Environmental Science & Technology Letters
Jackie Bridges, Peter Griffiths, Emily Oliver, Ruth Pickering,
Background Existing evidence indicates that reducing nurse staffing and/or skill mix adversely affects care quality. Nursing shortages may lead managers to dilute nursing team skill mix, substituting assistant personnel for registered nurses (RNs). However, no previous studies have described the relationship between nurse staffing and staff–patient interactions. Setting Six wards at two English National Health Service hospitals. Methods We observed 238 hours of care (n=270 patients). Staff–patient ...
Tópico(s): Global Health Workforce Issues
2019 - BMJ | BMJ Quality & Safety
Marc‐Oliver Wright, Jackie Tropp, Donna Schora, Mary Dillon-Grant, Kari Peterson, Sue Boehm, Ari Robicsek, Lance R. Peterson,
Catheter hub decontamination requires a thorough scrub and compliance varies. This study evaluates the effectiveness of a disinfection cap with 70% alcohol in preventing contamination/infection.A 3-phased, multifacility, quasi-experimental study of adult patients with central lines divided into P1 (baseline), when the standard scrub was used; P2, when the cap was used on all central lines; and P3, when standard disinfection was reinstituted. House-wide central-line associated bloodstream infection ( ...
Tópico(s): Infection Control in Healthcare
2012 - Elsevier BV | American Journal of Infection Control
Rachel Hardisty, Alexandra Erven, Karen M. Logan, Susan Morse, Sylvia Guionaud, Sara Sancho–Oliver, A. Jackie Hunter, Steve D. M. Brown, Karen P. Steel,
Otitis media is the most common cause of hearing impairment in children and is primarily characterized by inflammation of the middle ear mucosa. Yet nothing is known of the underlying genetic pathways predisposing to otitis media in the human population. Increasingly, large-scale mouse mutagenesis programs have undertaken systematic and genome-wide efforts to recover large numbers of novel mutations affecting a diverse array of phenotypic areas involved with genetic disease including deafness. As ...
Tópico(s): Congenital Ear and Nasal Anomalies
2002 - Springer Science+Business Media | Journal of the Association for Research in Otolaryngology
Angela Vincent, Oliver Lily, Jackie Palace,
Abstract Autoantibodies to acetylcholine receptors and to voltage-gated calcium and potassium channels are thought to be pathogenic in three peripheral neurological disorders: myasthenia gravis, the Lambert Eaton syndrome and acquired neuromyotonia. However, evidence for the role of antibodies in conditions involving the central nervous system, is scanty or unclear. This review describes the ways in which the roles of autoantibodies have been defined in the peripheral diseases, and discusses the more controversial ...
Tópico(s): Autoimmune Neurological Disorders and Treatments
1999 - Elsevier BV | Journal of Neuroimmunology
Jackie Beth Shilcutt, Kimberly L. Oliver, Raquel Aranda,
In an attempt to respond to the calls for dance educators to explore alternatives to harmful authoritarian teaching practices, we propose that one such route forward is an Activist Approach to teaching, which was originally developed in physical education contexts as a student-centered, inquiry-based approach that attends to issues of embodiment while listening and responding to students over time. The purpose of this study is to describe what an Activist Approach to teaching looks like in dance. ...
Tópico(s): Inclusion and Disability in Education and Sport
2020 - Taylor & Francis | Journal of Dance Education
Sarah Bick, Helen Buxton, Rachel P. Chase, Ian Ross, Zaida Adriano, Drew Capone, Jackie Knee, Joe Brown, Rassul Nalá, Oliver Cumming, Robert Dreibelbis,
Abstract Background Although theory-driven evaluations should have empirical components, few evaluations of public health interventions quantitatively test the causal model made explicit in the theory of change (ToC). In the context of a shared sanitation trial (MapSan) in Maputo, Mozambique, we report findings of a quantitative process evaluation assessing intervention implementation, participant response and impacts on hypothesised intermediary outcomes on the pathway to trial health outcomes. We ...
Tópico(s): Health Policy Implementation Science
2021 - BioMed Central | BMC Public Health
F. Lucy Raymond, Patrick Tarpey, Sarah Edkins, Calli Tofts, Sarah O’Meara, Jon W. Teague, Adam Butler, Claire Stevens, Syd Barthorpe, Gemma Buck, Jennifer Cole, Ed Dicks, Kristian Gray, Kelly Halliday, Katy Hills, Jonathon Hinton, David Jones, Andrew Menzies, Janet Perry, Keiran Raine, Rebecca Shepherd, Alexandra Small, Jennifer Varian, Sara Widaa, Uma Mallya, Jenny Moon, Ying Luo, Marie Shaw, Jackie Boyle, Bronwyn Kerr, Gillian Turner, Oliver Quarrell, Trevor Cole, Douglas F. Easton, Richard Wooster, Martin Bobrow, Charles E. Schwartz, Jozef Gécz, Michael R. Stratton, P. Andrew Futreal,
We have identified one frameshift mutation, one splice-site mutation, and two missense mutations in highly conserved residues in ZDHHC9 at Xq26.1 in 4 of 250 families with X-linked mental retardation (XLMR). In three of the families, the mental retardation phenotype is associated with a Marfanoid habitus, although none of the affected individuals meets the Ghent criteria for Marfan syndrome. ZDHHC9 is a palmitoyltransferase that catalyzes the posttranslational modification of NRAS and HRAS. The degree ...
Tópico(s): Macrophage Migration Inhibitory Factor
2007 - Elsevier BV | The American Journal of Human Genetics
Mary Durand Thomas, Jane Beaven, Joann Blacksmith, Ethel Stitt Ekland, Jan von Hein, Oliver H. Osborne, Jackie Reno,
The purpose of this study was to describe the meaning of work for nurses employed in two state psychiatric hospitals. Nurses at both hospitals participated in designing and carrying out the research. In Phase I, nurses described situations in which they had been observers or participant observers and the way that they understood what was occurring in the situations described. The data from these descriptions were analyzed in collaboration with small groups of nurse co-investigators at each hospital. ...
Tópico(s): Geriatric Care and Nursing Homes
1999 - Elsevier BV | Archives of Psychiatric Nursing
Jason Harris, Maria S. Shadrina, Carlos Oliver, Jackie Vogel, Anthony Mittermaier,
Tubulins are an ancient family of eukaryotic proteins characterized by an amino-terminal globular domain and disordered carboxyl terminus. These carboxyl termini play important roles in modulating the behavior of microtubules in living cells. However, the atomic-level basis of their function is not well understood. These regions contain multiple acidic residues and their overall charges are modulated in vivo by post-translational modifications, for example, phosphorylation. In this study, we describe ...
Tópico(s): Advanced NMR Techniques and Applications
2017 - Wiley | Protein Science
Adrian Hornby, Yan Lavallée, Jackie E. Kendrick, Silvio De Angelis, Anthony Lamur, Oliver D. Lamb, Andreas Rietbrock, Gustavo Chigna,
Abstract Gas‐and‐ash explosions at the Santiaguito dome complex, Guatemala, commonly occur through arcuate fractures, following a 5‐ to 6‐min period of inflation observed in long‐period seismic signals. Observation of active faults across the dome suggests a strong shear component, but as fault propagation generally proceeds through the coalescence of tensile fractures, we surmise that explosive eruptions require tensile rupture. Here, we assess the effects of temperature and strain rate on fracture ...
Tópico(s): High-pressure geophysics and materials
2019 - Wiley | Journal of Geophysical Research Solid Earth
Elizabeth Ford, Philip Rooney, Peter D. Hurley, Seb Oliver, Stephen Bremner, Jackie Cassell,
Background Patient health information is collected routinely in electronic health records (EHRs) and used for research purposes, however, many health conditions are known to be under-diagnosed or under-recorded in EHRs. In research, missing diagnoses result in under-ascertainment of true cases, which attenuates estimated associations between variables and results in a bias towards the null. Bayesian approaches allow the specification of prior information to the model, such as the likely rates of ...
Tópico(s): Chronic Disease Management Strategies
2020 - Frontiers Media | Frontiers in Public Health
William Carter, Andreas Rietbrock, Yan Lavallée, Ellen Gottschämmer, Alejandro Díaz‐Moreno, Jackie E. Kendrick, Oliver D. Lamb, Paul A. W. Wallace, Gustavo Chigna, Silvio De Angelis,
Long-term eruptive activity at the Santiaguito lava dome complex, Guatemala, is characterised by the regular occurrence of small-to-moderate size explosions from the active Caliente dome. Between November 2014 and December 2018, we deployed a seismo-acoustic network at the volcano, which recorded several changes in the style of eruption, including a period of elevated explosive activity in 2016. Here, we use a new catalogue of explosions to characterise changes in the eruptive regime during the ...
Tópico(s): Earthquake Detection and Analysis
2020 - Elsevier BV | Journal of Volcanology and Geothermal Research
Jaason M. Geerts, Donna Kinnair, Paul A. Taheri, Ajit Abraham, Joon Mo Ahn, Rifat Atun, Lorena Barberia, Nigel J. Best, Rakhi Dandona, Adeel Abbas Dhahri, Louise Emilsson, Julian R. Free, Michael Gardam, William Geerts, Chikwe Ihekweazu, Shanthi Johnson, Allison Kooijman, A Lafontaine, Eyal Leshem, Caroline Lidstone-Jones, Erwin Loh, Oscar Lyons, Khalid Ali Fouda Neel, Peter Nyasulu, Oliver Razum, Hélène Sabourin, Jackie Taylor, Hamid Sharifi, Vicky Stergiopoulos, Brett Sutton, Zunyou Wu, Marc Bilodeau,
Importance The COVID-19 pandemic is the greatest global test of health leadership of our generation. There is an urgent need to provide guidance for leaders at all levels during the unprecedented preresolution recovery stage. Objective To create an evidence- and expertise-informed framework of leadership imperatives to serve as a resource to guide health and public health leaders during the postemergency stage of the pandemic. Evidence Review A literature search in PubMed, MEDLINE, and Embase revealed 10 ...
Tópico(s): COVID-19 and healthcare impacts
2021 - American Medical Association | JAMA Network Open