Andrew Robson, Janet Martin Soskice, P. D. Jmes, Jenne Mannion, Cath Urquhart, Raymond Snoddy Media Editor, Rachel Stevenson, Richard Whitehead, Helen Studd, Helen Daniel, J. E. Humphrey, Catherine Riley, Matthew Syed, Robert Cole, Witold Rybczynski, giles tremlett, Richard Whitehiead, Zahid Hussain, Patricia Davies, Nick Batey, Patricia Mellor, Maggie Alderson, Jane MacQuitty, Simon Barnes, Gary Neville, Robert Vincent, Mike Gerrard and Joanna Hunter, Salome Munuo, Peter B. Buller, Paul Hoggart, Mark Souster, Dominic Walsh and Adam Jones, George Herrison, David Rhys Jones, paul Hoggart's, Jean Alesi, Spiro James, Zoe Wanamaker and Anna Chancellor, Philip Howard, Michael Schumacher, Ian Cobain, Leslie Fielding, David Chater, Angela Court, James Bone, Philippa Gee, Alison Kervin, Clive Davis, Ruth Gorb, Cathrine Riley, E. Jane Dickson, Anne Robinson, Sharon Linnard, GS, Francis Maude, Kevin Eason, Jonathan Lowe, Clare Stewart, Miranda Sawyer, M. D. Dyke, Giles Coren, Andrew Bray, Antonia Senior, Martin Fletcher, Carl Evans, Ben Webster Transport Correspondent, Russell Jenkins, Paul Wilkinson and Ian Cobain, Pat Gibson, Valerie Elliott Countryside Editor, David McVay, AC, John Clarke, Penny Parrick, Corin Redgrave, John Phelps, EP, Alan Mundy, Piers Townley, Jeff Dunne, Dominic Walsh, Ruth Gledhill, Ruvini N. Hewavidana, Rob Penn, Victoria Segal, wendy earrig, Jill Dupleix, Tim Reid, Grainne Gilmore, Colin Reeve, Carol Price, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Bob Constanduros, Henry Aubrey-Fletcher, Richard Ford Home Correspondent, Geoff Hoon, Jo Morris, Robin Young, Russell White, Candida Crewe, Rodney Milnes, Liz Price, CD, Michael Brewer, Jenny MacArthur, Nick Wyke, Niki Lauda, David Hands, Charles Bremner, Valerie Elliott Countryside Editor and Tom Baldwin, Helen Rumbelow, Paul Wilkinson and Russell Jenkins, Adam Mars-Jones's, Peter Barnard, Tim Teeman, Nicholas Wapshott, Mark Court, Arthur Leathley City Correspondent, Derwent May, James Urquhart, Angela Jameson, Susan Emmett, Kate Muir, Jane Briggs, Ivan Hewett, J. M. W. Turner's, JJ, Will Greenwood, Russell Kempson, James Buxton, Paula Hawkins, Emma Mahony, Isobel Shepherd Smith, Mary Gold, Daniel McGrory, Paul Armstrong, Oliver Kay, Felipe Fernandez-Armesto, Nicole Swengley, Stephen Anderton, Martin Cullingford, Amber Cowan, Nigel Williamson, Ed Potton, Mark Atherton, Lisa Armstrong, Rick Broadbent, Patrick G. J. Moore, Tom Baldwin, Michael Durham, Sam Coates, Ian Adcock, Andy Stephens Football Focus, Simon de Bruxelles, John Hopkins Golf Correspondent, Mike Thomas, IH, JC, Ed Gray, Adam Jones, Victoria O'Brien, John Depp, Raymond Keene, Kimi Raikkonen, Matthew Pryor, Caroline Lawrence, Matt Dickinson, Rurobet Odds, Kenneth Cranham, Lucy Pinney, Alison Kervin Rugby Editor, James Allcock, Christine Buckley Industrial Editor, Roni Size, Greg Hurst Parliamentary Correspondent, Sam Bussey, Debra Crime, Min Cooper, Eddie Jordan, Gill Morgan Editor of The Times Magazine, james brown, Rob Chapman, Helen Nugent, Tony Husband, Christopher Martin-Jenkins Chief Cricket Correspondent, Damian Whitworth, John Givens, Ross Leckie, peter marlow, Roger Boyes, David Stewart, Emily Davies, Oliver August, Nick Hasell, Caroline Morrow Brown, Graham Searjeant Personal Investor, Pamela Atherton, David Hands Rugby Correspondent, James Collard, Mrs L Grinter, Mike Mulvihill, Martin Fletcher European Correspondent, BN, Anne Ashworth, John Goodbody, Dominic Kennedy, RL, Philip Webster Political Editor, James Pringle, Sophie Ratcliffe, Kevin Eason and Tim Rice, Paul McCann Media Correspondent, Kevin McCarra, Matthew Parris, Robin Dutt, Jennai Cox, Alex Dingwall-Main, James brown, Jeremy Healy, Mark Hodkinson, George Caulkin, Chris McGrath, Tim Wapshott, Jo Morris and Steve Keenan, Walter Gammie, Catriona Marchant, Ben MacIntyre, Lea Paterson Economics Editor, Helen Pridham, DC, vinny lee, Ron Dennis, team principal, Richard Beeston, alan jacks…, Alison Gibson, brigitte iacombe, Jeremy Bermridge, Lewis Stuart, Gary Duncan Economics Correspondent, Martin Waller, Michael Horsnell, Chris Ayres, Lisa Verrico, Danny Baker, Fran Littlewood, Mark Baldwin, Laura Peek, E. J. Dwyer, Kathleen Wyatt, James Jackson, Heath Brown, Clare Thomson, Dr Thomas Stuttaford, Jill Crawshaw, Paul Carter, Paul Cartledge, Nicholas Hammond, Anthony Snodgrass, Dorothy J. Thompson, Fred Dellar, Sam Kiley, Tom Chesshyre, Jennifer Rowson, Elizabeth Buchan, Valerie Grove, Neil Cooper, Martin Kemp, Tom Baldwin Deputy Political Editor, Clive Mathieson Telecommunications Correspondent, Fiona Beckett, SJ, Alan Lee Racing Correspondent, Michael Moore, Sally Patten, Nigel Hawkes Health Editor and Helen Rumbelow, sheila keating, Edward Gorman Sailing Correspondent, James Luckhurst, Matthew Craig, Sarah Modlock, David Daiton, nicholas rossiter, John Clees, Catherine Riley Motoring Editor, Patience Wheatcroft, Edward Marriott, Rubens Barrichello, Christopher Irvine, Chloe Bryan-Brown, Simon Gawthorne,
... festival suggestions Jersey Checking in Chateau de la Vallee Bleue, St Chartier, France British Airways Holidays Chinese ... Man to Watch Eurobet Odds Jaques be nimble, Jacques be quick The Drivers Dunywoody's Tip Man ...
2001 - Gale Group | TDA
Fabrice Vallée, Jacques Lukasik,
Abstract Resonantly enhanced four-wave sum frequency mixing in phase matched carbon monoxide leads to the generation of continuously tunable over 1200 cm -1 coherent VUV radiation in the 1150 A range. Experiments allow to determine the VUV absorption cross sections and indices of refraction of CO. Multiphoton photolysis of CO has been observed and confirmed by the VUV absorption in atomic carbon.
Tópico(s): Spectroscopy and Laser Applications
1982 - Elsevier BV | Optics Communications
Yann Mikaeloff, Anne de Saint Martin, Josette Mancini, Sylviane Peudenier, Jean‐Michel Pédespan, Louis Vallée, Jacques Motté, Marie Bourgeois, Alexis Arzimanoglou, Olivier Dulac, Catherine Chiron,
To evaluate the efficacy and tolerability of topiramate (TPM) as add-on therapy in children less than 12 years of age with refractory epilepsy, according to epilepsy syndromes, we conducted an open, prospective, pragmatic and multicenter study in France. Efficacy was assessed, especially according to epilepsy syndromes, as well as tolerability. We included 207 children (41 of whom were less than 4 years of age). TPM was effective (responders with >50% decrease in seizure frequency) in 50% of 128 patients ...
Tópico(s): Neuroscience and Neuropharmacology Research
2003 - Elsevier BV | Epilepsy Research
Stéphane Moreau, Pascal Coudert, Catherine Rubat, Daniel Gardette, Danielle Vallee‐Goyet, J. COUQUELET, P Bastide, P Tronche,
... Moreau, Pascal Coudert, Catherine Rubat, Daniel Gardette, Danielle Vallee-Goyet, Jacques Couquelet, Pierre Bastide, and Pierre TroncheCite this: J. ...
Tópico(s): Synthesis and Reactivity of Heterocycles
1994 - American Chemical Society | Journal of Medicinal Chemistry
François Vallée, Jacques Lobry, Olivier Deblecker,
Wind power penetration is expected to be largely increased in the near future. Nevertheless, due to the high variability of wind, the increase of the installed capacity in wind energy could sometimes lead to a stopping of nonadjustable power plants if the planning of those units was still decided without considering a realistic estimation of the available wind potential. In that way, and as it is illusory to imagine that all the installed wind capacity will always be produced, this article proposes ...
Tópico(s): Wind and Air Flow Studies
2008 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Power Systems
J-M Revest, Nadia Kaouane, Magali Mondin, A Le Roux, Françoise Rougé‐Pont, Monique Vallée, Jacques Barik, François Tronche, Aline Desmedt, Pier‐Vincenzo Piazza,
The activation of glucocorticoid receptors (GR) by glucocorticoids increases stress-related memory through the activation of the MAPK signaling pathway and the downstream transcription factor Egr-1. Here, using converging in vitro and in vivo approaches, respectively, GR-expressing cell lines, culture of hippocampal neurons, and GR genetically modified mice (GRNesCre), we identified synapsin-Ia/Ib as one of the effectors of the glucocorticoid signaling cascade. Stress and glucocorticoid-induced activation ...
Tópico(s): Neuroscience and Neuropharmacology Research
2010 - Springer Nature | Molecular Psychiatry
François Vallée, Jacques Lobry, Olivier Deblecker,
Following several governmental policies trying to reduce CO emissions, renewable energies have been largely promoted during the last decade. Among the green energies that have been developed, wind can actually be seen as one of the most promising solution if we refer to its past and predicted evolutions. However and, even though wind can be considered as an interesting alternative to fossil fuels, it is imperious to emphasize on problematic situations that could be due to the intermittent behavior ...
Tópico(s): Renewable energy and sustainable power systems
2007 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Power Systems
Christine B. Chung, Bruno C. Vande Berg, T. Tavernier, Anne Cotten, Jean‐Denis Laredo, C. Vallée, Jacques Malghem,
Tópico(s): Medical Imaging and Analysis
2004 - Springer Science+Business Media | Skeletal Radiology
Antonio Ugolini, Mireille Kenigsberg, Alexey Rak, François Vallée, Jacques Houtmann, Maryse Lowinski, Cécile Capdevila, Jean Khider, Eva Albert, Nathalie Martinet, Conception Nemecek, Sandrine Grapinet, Eric Bacqué, Manfred Roesner, Christine Delaisi, Loreley Calvet, Fabrice Bonche, Dorothée Sémiond, Coumaran Égile, Hélène Goulaouic, Laurent Schio,
The HGF/MET pathway is frequently activated in a variety of cancer types. Several selective small molecule inhibitors of the MET kinase are currently in clinical evaluation, in particular for NSCLC, liver, and gastric cancer patients. We report herein the discovery of a series of triazolopyridazines that are selective inhibitors of wild-type (WT) MET kinase and several clinically relevant mutants. We provide insight into their mode of binding and report unprecedented crystal structures of the Y1230H ...
Tópico(s): PI3K/AKT/mTOR signaling in cancer
2016 - American Chemical Society | Journal of Medicinal Chemistry
Richard Wubbolts, Mar Fernandez‐Borja, Ingrid Jordens, Eric A. Reits, Simone Dusseljee, Christophe J. Echeverri, Richard B. Vallee, Jacques Neefjes,
ABSTRACT MHC class II molecules exert their function at the cell surface by presenting to T cells antigenic fragments that are generated in the endosomal pathway. The class II molecules are targetted to early lysosomal structures, termed MIIC, where they interact with antigenic fragments and are subsequently transported to the cell surface. We previously visualised vesicular transport of MHC class II-containing early lysosomes from the microtubule organising centre (MTOC) region towards the cell ...
Tópico(s): Autophagy in Disease and Therapy
1999 - The Company of Biologists | Journal of Cell Science
Alexandre Vallée, Jacques Blacher, Alain Cariou, Emmanuel Sorbets,
Background Blended learning, which combines face-to-face learning and e-learning, has grown rapidly to be commonly used in education. Nevertheless, the effectiveness of this learning approach has not been completely quantitatively synthesized and evaluated using knowledge outcomes in health education. Objective The aim of this study was to assess the effectiveness of blended learning compared to that of traditional learning in health education. Methods We performed a systematic review of blended ...
Tópico(s): Health Literacy and Information Accessibility
2019 - JMIR Publications | Journal of Medical Internet Research
... 53, Issue 2 p. 181-181 Book Review VALLEE, JACQUES, AND JANINE. Challenge to Science: The UFO Enigma. ...
Tópico(s): History of Science and Natural History
1969 - Wiley | Science Education
Kenneth Chappell, Bruno Francou, Christophe Habib, Thomas Huby, Marco Leoni, Aurélien Cottin, Florian Nadal, Éric Adnet, Eric E. Paoli, Christophe Oliveira, Céline Verstuyft, Anne Davit–Spraul, Pauline Gaignard, Élise Lebigot, Jean‐Charles Duclos‐Vallée, Jacques Young, Peter Kamenický, David R. Adams, Andoni Echaniz‐Laguna, Emmanuel Gonzalès, Claire Bouvattier, Agnès Linglart, Véronique Picard, Emilie Bergoin, Emmanuel Jacquemin, Anne Guiochon‐Mantel, Alexis Proust, Jérôme Bouligand,
To date, the usage of Galaxy, an open-source bioinformatics platform, has been reported primarily in research. We report 5 years' experience (2015 to 2020) with Galaxy in our hospital, as part of the "Assistance Publique-Hôpitaux de Paris" (AP-HP), to demonstrate its suitability for high-throughput sequencing (HTS) data analysis in a clinical laboratory setting.Our Galaxy instance has been running since July 2015 and is used daily to study inherited diseases, cancer, and microbiology. For the molecular ...
Tópico(s): Genomics and Phylogenetic Studies
2021 - American Association for Clinical Chemistry | Clinical Chemistry
François Vallée, Jacques Lobry, Olivier Deblecker,
Abstract Given the actual context of increased dispersed generation and highly loaded lines, probabilistic methods are more and more required to take into account the stochastic behavior of electrical network components (possible spate of outages by use of the electrical network near its physical limits) in reliability studies. To implement those probabilistic methods, numerical Monte Carlo simulations are typically used and can be divided in two categories: sequential and non‐sequential techniques. ...
Tópico(s): Wind and Air Flow Studies
2008 - Wiley | European Transactions on Electrical Power
J-M Revest, Nadia Kaouane, Magali Mondin, A Le Roux, Françoise Rougé‐Pont, Monique Vallée, Jacques Barik, François Tronche, Aline Desmedt, P.V. Piazza,
Glucocorticoid treatment induces expression of Egr-1 and synapsin-I proteins in primary culture of hippocampal neurons
Tópico(s): Neuroscience and Neuropharmacology Research
2010 - Springer Nature | Molecular Psychiatry
Jean Paul Durand, Louis Vallée, Jean-Jacques De Pina, Hugues Tolou,
Tópico(s): Malaria Research and Control
2000 - Centers for Disease Control and Prevention | Emerging infectious diseases
Mbarka Dakouane‐Giudicelli, Sophie Brouillet, Waël Traboulsi, Antoine Torre, Guillaume Vallat, Sammy Si Nacer, Marion Vallée, Jean‐Jacques Feige, Nadia Alfaidy, Philippe de Mazancourt,
Netrin-4 is a secreted member of the laminin-related protein family, known to be involved in axonal guidance and endothelial cell survival, proliferation, and migration. We have recently reported the cellular localization of netrin-4 and its receptor neogenin in human first trimester and term placenta. A strong expression of netrin-4 was observed in trophoblast and in endothelial cells, suggesting a potential role of this protein in placental angiogenesis. In relation to human pregnancy, it has ...
Tópico(s): Apelin-related biomedical research
2015 - Elsevier BV | Placenta
J.H. Abraini, Laurent Chazalviel, Benoît Haelewyn, Mickaël Degoulet, Jean-Éric Blatteau, Nicolas Vallée, Jean‐Jacques Risso, S. Besnard,
Recent data have shown that normobaric oxygen (NBO) increases the catalytic and thrombolytic efficiency of recombinant tissue plasminogen activator (rtPA) in vitro, and is as efficient as rtPA at restoring cerebral blood flow in rats subjected to thromboembolic brain ischemia. Therefore, in the present study, we studied the effects of hyperbaric oxygen (HBO) (i) on rtPA-induced thrombolysis in vitro and (ii) in rats subjected to thromboembolic middle cerebral artery occlusion-induced brain ischemia. ...
Tópico(s): Stroke Rehabilitation and Recovery
2016 - Medknow | Medical Gas Research
Alain Boussuges, Sarah Rives, Julie Finance, Guillaume Chaumet, Nicolas Vallée, Jean‐Jacques Risso, Fabienne Brégeon,
Background: Diagnosing diaphragm dysfunction in the absence of complete paralysis remains difficult. The aim of the present study was to assess the normal values of the thickness and the inspiratory thickening of both hemidiaphragms as measured by ultrasonography in healthy volunteers while in a seated position. Methods: Healthy volunteers with a normal pulmonary function test were recruited. The diaphragmatic thickness was measured on both sides at the zone of apposition of the diaphragm to the ...
Tópico(s): Congenital Diaphragmatic Hernia Studies
2021 - Frontiers Media | Frontiers in Medicine
Jacques Vallée, Hubert Lipinski, Robert Johansen, Thaddeus Wilson,
1975 - American Association for the Advancement of Science | Science
François G. Meyer, Jacques Vallée,
The authors have studied the effect of tool-making on man's evolution. They argue that growth is not exponential, but hyperbolic, and that a positive feedback exists linking technological development to population. Exploring the nature of this mechanism in order to improve the predictive capability of global models is the goal of the article.
Tópico(s): Chaos, Complexity, and Education
1975 - Elsevier BV | Technological Forecasting and Social Change
Tópico(s): Cognitive Computing and Networks
1981 - Elsevier BV | Computer Networks (1976)
Jacques Vallée, A.C. Hastings, G. Askevold,
A series of remote viewing experiments were run with 12 participants who communicated through a computer conferencing network. These participants, who were located in various regions of the United States and Canada, used portable terminals in their homes and offices to provide typed descriptions of 10 mineral samples. These samples were divided into an open series and a double-blind series. A panel of five judges was asked to match the remote viewing descriptions against the mineral samples by a ...
Tópico(s): Cognitive Science and Education Research
1976 - Institute of Electrical and Electronics Engineers | Proceedings of the IEEE
Valérie Langlois, Karine Vallée‐Réhel, Jean Jacques Péron, Alain Le Borgne, Michael Walls, Philippe Guérin,
Graft copolymers were synthetized by radical copolymerization of poly(dl lactic acid) (PLA) methacrylate, a hydrolyzable macromonomer, and tert-butyl acrylate, a hydrophobic monomer in order to obtain degradable polymers. Cast films have been immersed in artificial sea water. The influence of different parameters on the kinetics of hydrolytic degradation have been examined, including the tert-butyl acrylate/macromonomer molar ratio, the nature of the PLA end group (acid or ester functionality), the ...
Tópico(s): Microplastics and Plastic Pollution
2002 - Elsevier BV | Polymer Degradation and Stability
Tópico(s): Multimedia Communication and Technology
1976 - Elsevier BV | Computer Networks (1976)
François Vallée, Christophe Versèle, Jacques Lobry, Francis Moiny,
In this paper, an original non-sequential Monte Carlo simulation tool is developed. This tool permits to compute the optimal dispatch of classical (coal, oil, etc.) thermal generation in order to minimize polluting gases (NOx, CO2, etc.) emissions in presence of wind power and under constraints. These constraints include, e.g., the maximal generation cost or the ability of the electrical system to cover the load, … In comparison with existing analytical tools that are based on restrictive hypotheses ...
Tópico(s): Wind and Air Flow Studies
2012 - Elsevier BV | Renewable Energy
Réda Salem, Fabrice Vallée, François Dépret, Jacques Callebert, Jean Maurice, Philippe Marty, Joaquim Matéo, Catherine Madadaki, Emmanuel Houdart, Damien Bresson, Sébastien Froelich, Christian Stapf, Didier Payen, Alexandre Mebazaa,
Abstract Introduction The occurrence of cardiac dysfunction is common after subarachnoid hemorrhage (SAH) and was hypothesized to be related to the release of endogenous catecholamines. The aim of this prospective study was to evaluate the relationship between endogenous catecholamine and cardiac dysfunction at the onset and during the first week after SAH. Methods Forty consecutive patients admitted for acute SAH without known heart disease were included. Catecholamine plasma concentrations and ...
Tópico(s): Traumatic Brain Injury and Neurovascular Disturbances
2014 - BioMed Central | Critical Care
Olivier Castagna, Jean-Éric Blatteau, Nicolas Vallée, Bruno Schmid, Jacques Regnard,
This study aimed at demonstrating that the neoprene wetsuit provides not only thermal protection. Compression it exerts on the diver’s shell significantly impacts hydromineral homeostasis by restraining the systemic vascular capacity and secondarily increasing urine output on dry land and during scuba diving. 8 healthy divers underwent five 2-h sessions: sitting out of water in trunks (control situation), sitting out of water wearing a wetsuit, and 3 wetsuit scuba-immersed sessions at 1, 6 and 12 ...
Tópico(s): Cardiovascular and exercise physiology
2013 - Thieme Medical Publishers (Germany) | International Journal of Sports Medicine
VALLÉE, Jacques, éd., Tocqueville au Bas-Canada. Éditions du Jour, 1973, 187 p. $3.50.. An article from ...
Tópico(s): Canadian Identity and History
1974 - Institut d'histoire de l'Amérique française | Revue d histoire de l Amérique française
Laurent Chazalviel, Hélène David, Benoît Haelewyn, Jean-Éric Blatteau, Nicolas Vallée, Jean‐Jacques Risso, S. Besnard, Jacques H. Abraini,
Sir, Neurons in the ischaemic penumbra are at risk from ischaemia-induced constrained oxygen delivery. Therefore, increasing arterial oxygen content by normobaric oxygen therapy (NBO) has been thought a logical strategy, and as expected further shown to increase markedly and rapidly the very low tissue oxygen pressure that prevails in the ischaemic penumbra (Shin et al. , 2007; Baskerville et al. , 2011). However, due to controversial results in rodent stroke models, there is still no clear consensus ...
Tópico(s): Diabetic Foot Ulcer Assessment and Management
2016 - Oxford University Press | Brain