Produção Nacional
Revisado por pares
Larissa Bazela Maschio-Signorini, Gabriela Bottaro Gelaleti, Marina Gobbe Moschetta, Thaiz F. Borin, Bruna V. Jardim‐Perassi, Juliana Romano Lopes, Jéssica Zani Lacerda, Rosimeire Aparecida Roela, Newton Antonio Bordin, Lizandra A. Corrêa, Jessica P. Cardoso, Débora Aparecida Pires de Campos Zuccari,
Background: Cancer-associated fibroblast (CAFs) are the most abundant cells in the tumor microenvironment, able to secrete growth factors and act on tumor progression. Melatonin is associated with several mechanisms of action with oncostatics and oncoprotectors effects, and also participate in the reduction of synthesis of surrounding fibroblasts and endothelial cells in breast cancer. Objective: The objectives of this study were to determine the effectiveness of melatonin in cell viability and expression ...
Tópico(s): Circadian rhythm and melatonin
2016 - Bentham Science Publishers | Anti-Cancer Agents in Medicinal Chemistry
Produção Nacional
Revisado por pares
Juliana Spadotto, Nadia Saito,
... with a community in a deprived peripheral neighbourhood, Jardim Romano, in São Paulo. Key findings highlight the concept ...
Tópico(s): Participatory Visual Research Methods
2023 - Taylor & Francis | Globalisation Societies and Education
Produção Nacional
Revisado por pares
Bernardete Weber, Ângela Cristine Bersch-Ferreira, Camila Ragne Torreglosa, Maria Beatriz Ross-Fernandes, Jacqueline T. da Silva, Andrea Galante, Enilda de Sousa Lara, Rosana Perim Costa, Rafael Marques Soares, Alexandre Biasi Cavalcanti, Emílio Hideyuki Moriguchi, Neide Maria Bruscato, Josiele Kesties, Lilian Vivian, Marina Schumacher, Waldemar de Carli, Luciano Marcelo Backes, Bruna R. Reolão, Milena P. Rodrigues, Dúnnia M.B. Baldissera, Glaucia S. Tres, Hugo Lisboa, João B.J., José Basileu Caon Reolão, Keyla L.A.L. Deucher, Maiara Cantarelli, Aline Lucion, Daniela Rampazzo, Vanessa Maria Bertoni, Rosileide S. Torres, Adriana O.L. Verríssimo, Aldair S. Guterres, Andrea F.R. Cardos, Dalva B.S. Coutinho, Mayara Galisse NEGRÃO, Mônica F.A. Alencar, Priscila Matos de Pinho Costa, Socorro Nazaré Araújo Almeida Barbosa, Ana P.P.F. Carvalho, Maria I.S. Taboada, Sheila Alves Pereira, Raul von der Heyde, Francisca Eugênia Zaina Nagano, Rebecca Baumgartner, Fernanda P. Resende, Ranata Tabalipa, Ana C. Zanini, Michael J.R. Machado, Hevila Araujo, Maria Laura Verissimo Teixeira, Gabriela Corrêa Souza, Priccila Zuchinali, Bianca M. Fracasso, Karen Ulliam, Marina Schumacher, Moara Pierotto, Thamires de Souza Hilário, Daniele M.O. Carlos, Cíntia G.N.C. Cordeiro, D. De Carvalho, Marília S. Gonçalves, Valdiana B. Vasconcelos, Rosa Bosquetti, Raira Pagano, Marcelo Luz Pereira Romano, César Jardim, Bernardo Noya Alves de Abreu, Aline Marcadenti, Alessandra R. Schmitt, Ângela Maria Vicente Tavares, Christiane Carvalho Faria, Flávia Moraes Silva, Jaqueline da Silva Fink, Raquel Milani El Kik, Clarice F. Prates, Cristiane S. Vieira, Elaine F. Adorne, Ellen Hettwer Magedanz, Fernanda Lourega Chieza, Ingrid S. Silva, Joise M. Teixeira, Eduardo P. Trescastro, Livia Pellegrini, Jéssika Cefrin Dantas Neris, Cristina T. Telles, Antônio Carlos Sobral Sousa, Andreza Santos Almeida, Ariane A. Costa, José A.C. Carmo, Juliana T. Silva, Luciana Vieira Sousa Alves, Saulo Sales, María Elena Ramos, Marilia C.S. Lucas, Mônica Damiani, Patrícia Cristina Cardoso, Salvador S. Ramos, Clenise F. Dantas, Amanda Lopes, Ana M.P. Cabral, Ana C.A. Lucena, Auriene L. Medeiros, Bernardino B. Terceiro, Neuma M.F.S. Leda, Sandra R.D. Baía, Josilene Maria Ferreira Pinheiro, Alexandra N. Cassiano, Andressa N.L. Melo, Anny K.O. Cavalcanti, Camila V.S. Souza, Dayanna Joyce Marques Queiroz, Hercilla N.C.F. Farias, Larissa Camila Ferreira Souza, Letícia Sabino Santos, Luana R.M. Lima, Meg S. Hoffmann, Átala Safira Silva Ribeiro, Daniel França Vasconcelos, Eliane Said Dutra, Marina Ito, José Albuquerque de Figueiredo Neto, Alexsandro F. Santos, Rosângela Maria Lopes de Sousa, Luciana Pereira Pinto Dias, Maria Tereza Medeiros Aureliano de Lima, Victor G. Modanesi, Adriana Fonseca Teixeira, Luciana C.N.C.D. Estrada, Paulo Victor Gomes Modanêsi, Adriana Barros Gomes, Bárbara Rafaela Santos da Rocha, Cristina Teti, Marta M. David, Bruna M. Palácio, Délcio G.S., Érica H.S. Faria, Michelle C.F. Oliveira, Rose Mary Uehara, Sandramara Sasso, Annie Seixas Bello Moreira, Ana C.A.H. Cadinha, Carla W.M. Pinto, Mariana P. Castilhos, Mariana Fernandes Costa, Cristiane Kovacs, Daniel Magnoni, Quênia Silva, Michele F.C.A. Germini, Renata A. da Silva, Aline S. Monteiro, Karina Gama dos Santos, Priscila Moreira, Fernanda C. Amparo, Catharina C.J. Paiva, Soraia Poloni, Diana S. Russo, Izabele V. Silveira, Maria Antonieta Moraes, Mirena Boklis, Quinto I. Cardoso, Annie Seixas Bello Moreira, Aline M.S. Damaceno, Elisa Maia dos Santos, Glauber Monteiro Dias, Cláudia Porto Sabino Pinho, Adrilene C. Cavalcanti, Amanda Silva de Macêdo Bezerra, Andrey Vieira de Queiroga, Isa Galvão Rodrigues, Tallita V. Leal, Viviane Sahade, Daniele A. Amaral, Diana S. Souza, Givaldo A. Araújo, Karine Duarte Curvello, Manuella Heine, Marília M.S. Barretto, Nailson A. Reis, Sandra Mary Lima Vasconcelos, Danielly C. Vieira, Francisco A. Costa, Jessica M.S. Fontes, Juvenal G.C. Neto, Laís Nanci Pereira Navarro, Raphaela Costa Ferreira, Patrícia de Menezes Marinho, Renata Torres Abib, Aline Longo, Eduardo Gehling Bertoldi, Lauren S. Ferreira, Lúcia Rota Borges, Norlai Alves Azevedo, Celma M. Martins, Juliana T. Kato, Maria Cristina de Oliveira Izar, Marina T. Asoo, Mariana Dutilh de Capitani, Valéria A. Machado, Waléria T. Fonzar, Sônia Lopes Pinto, Kellen C. Silva, Lúcia Helena Almeida Gratão, Sheila D. Machado, Susane R.U. de Oliveira, Josefina Bressan, Ana Paula Silva Caldas, Hatanne Carla Fialho Moraes Lima, Helen Hermana Miranda Hermsdorff, Tânia M. Saldanha, Silvia Eloíza Priore, Naoel H. Feres, Adila de Queiroz Neves, Loanda Maria Gomes Cheim, Nilma F. Silva, Sílvia R.L. Reis, Andreza M. Penafort, Ana Paula O. de Queirós, Geysa Maria Nogueira Farias, Mónica Santos, Cíntia L. Ambrózio, Cirília N. Camejo, Cristiano P. dos Santos, Gabriela da Silva Schirmann, Jorge L. Boemo, Rosane E.C. Oliveira, Súsi M.B. Lima, Vera M.S. Bortolini, Cristina Matos, Claiza Barretta, Clarice Maria Specht, Simone Raimondi de Souza, Cristina Silva Arruda, Priscila Aparecida Rodrigues, Otávio Berwanger,
This article reports the rationale for the Brazilian Cardioprotective Nutritional Program (BALANCE Program) Trial. This pragmatic, multicenter, nationwide, randomized, concealed, controlled trial was designed to investigate the effects of the BALANCE Program in reducing cardiovascular events. The BALANCE Program consists of a prescribed diet guided by nutritional content recommendations from Brazilian national guidelines using a unique nutritional education strategy, which includes suggestions of ...
Tópico(s): Diet and metabolism studies
2015 - Elsevier BV | American Heart Journal
Produção Nacional
Revisado por pares
Gabriela dos Santos Pinto, Luísa Jardim Corrêa de Oliveira, Ana Regina Romano, Lisandrea Rocha Schardosim, Maria Laura Menezes Bonow, Marcos Antônio Pacce, Marcos Britto Corrêa, Flávio Fernando Demarco, Dione Dias Torriani,
The aim of this retrospective study was to evaluate the longevity of restorations in the posterior primary teeth of children attending to a public paediatric dental clinic and to test the factors associated with failures. Patient records of 329 children (162 boys and 166 girls) were used for collecting and analyzing data. A total of 565 restorations in primary teeth were included in the study. All children enrolled in the study were classified as high caries risk. The longevity of restorations from ...
Tópico(s): Dental Research and COVID-19
2014 - Elsevier BV | Journal of Dentistry
Produção Nacional
Revisado por pares
Naiane do Nascimento Gonçalves, R.V. Rodrigues, Bruna V. Jardim‐Perassi, Marina Gobbe Moschetta, Juliana Romano Lopes, Jucimara Colombo, Débora Aparecida Pires de Campos Zuccari,
Background: Oral cancer is the most common type of head and neck cancer and its high rate of mortality and morbidity is closely related to the processes of angiogenesis and tumor metastasis. The overexpression of the pro-angiogenic genes, HIF-1α and VEGF, and pro-metastatic gene, ROCK-1, are associated with unfavorable prognosis in oral carcinoma. Melatonin has oncostatic, antiangiogenic and antimetastatic properties in several types of neoplasms, although its relationship with oral cancer has been ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2014 - Bentham Science Publishers | Anti-Cancer Agents in Medicinal Chemistry
Produção Nacional
Revisado por pares
Danielle de Souza Costa, Antoine Bechara, Jonas Jardim de Paula, Marco Aurélio Romano‐Silva, Humberto Corrêa, Guilherme Menezes Lage, Débora Marques de Miranda, Leandro Fernandes Malloy‐Diniz,
The biological underpinnings of sex-related differences in decision-making are still under-explored. The COMT gene is related to sexual dimorphism and with different choices made under uncertainty, albeit no study has specifically investigated a moderation effect of sex on the association between the COMT gene and the performance on decision-making paradigms. In this study, we investigated the influence of the COMT Val158Met polymorphism on Iowa Gambling Task (IGT) performance depending on sex in ...
Tópico(s): Stress Responses and Cortisol
2016 - Elsevier BV | Psychiatry Research
Produção Nacional
Revisado por pares
É.A. Costa, Marta Giovanetti, Lilian Silva Catenacci, Vagner Fonseca, Flávia Figueira Aburjaile, Flávia Löwen Levy Chalhoub, Joilson Xavier, Felipe Campos de Melo Iani, Marcelo Adriano da Cunha e Silva Vieira, Danielle Freitas Henriques, Daniele Barbosa de Almeida Medeiros, Maria Isabel Maldonado Coelho Guedes, Beatriz Senra Álvares da Silva Santos, Aila Solimar Gonçalves Silva, Renata de Pino Albuquerque Maranhão, Nieli Rodrigues da Costa Faria, Renata Farinelli de Siqueira, Túlio de Oliveira, Karina Ribeiro Leite Jardim Cavalcante, Noely Fabiana Oliveira de Moura, Alessandro Romano, Carlos F. Campelo de Albuquerque, Lauro César Soares Feitosa, José Joffre Martins Bayeux, Raffaella Bertoni Cavalcanti Teixeira, Osmaikon Lisboa Lobato, Silvokleio da Costa Silva, Ana María Bispo de Filippis, Rivaldo Venâncio da Cunha, José Lourenço, Luíz Carlos Júnior Alcântara,
Background: West Nile virus (WNV) was first sequenced in Brazil in 2019, when it was isolated from a horse in the Espírito Santo state. Despite multiple studies reporting serological evidence suggestive of past circulation since 2004, WNV remains a low priority for surveillance and public health, such that much is still unknown about its genomic diversity, evolution, and transmission in the country. Methods: A combination of diagnostic assays, nanopore sequencing, phylogenetic inference, and epidemiological ...
Tópico(s): Malaria Research and Control
2021 - Multidisciplinary Digital Publishing Institute | Pathogens
Stephen J. Chapman, Ruth Blanco‐Colino, S Pérez-Ajates, O Anabitarte Bautista, James Hodson, Ruth Blanco‐Colino, Stephen J. Chapman, James Glasbey, Francesco Pata, Gianluca Pellino, AS Soares, T. van Elst, Stephanie Van Straten, Dmitri Nepogodiev, James Hodson, Aditya Borakati, M F Bath, Ifat Yasin, Kenneth A McLean, Thomas Arthur, M Kovacević, S Delibegovic, Martin Karamanliev, Mohamed Swamad, R Žebrák, R Paramasivam, Anne Kraushaar Martensen, Helene Mathilde Larsen, Lukas Rädeker, Pia‐Elena Frey, Aristotelis Kechagias, Aurélien Venara, Émilie Duchalais, Argyrios Ioannidis, Francesco Pata, Gianluca Pellino, Sandro Pasquali, Andrea Simioni, Valeria Farina, Mauro Podda, Laura Lorenzon, ItSURG, V. Schaeff, Amy D. Otto, Matas Jakubauskas, T. R. van Elst, Michael J. J. Chu, Paul Fagan, Cameron I. Wells, A Alagoa João, António Sampaio Soares, Jovan Juloski, Ruth Blanco‐Colino, S Pérez-Ajates, O Anabitarte Bautista, Y. El Kasmy El Kasmi, Eloy Espín, Daniel Clerc, Cezar Ciubotaru, S S Popescu, A Yanishev, S Lee, Bahar Büşra Özkan, A Yagız Sen, M K Aktas, Bahadır Emre Baki, B Yüksek, James Glasbey, Sivesh K. Kamarajah, Kenneth A McLean, Aditya Borakati, Ifat Yasin, Rachel A Khaw, Emily Mills, R. Goodson, Nimish Thakral, Andrew D. Ablett, M Adra, I Kwek, S. Khan, Patrick Quinn, L R Manley, Abdul Badran, A Ramjeeawon, A Campbell, Haiyan Tan, Dupinderjit Rye, Nikitha Rajaraman, James G. Norman, Kritchai Vutipongsatorn, Georgios Solomou, Melika Akhbari, Ased Ali, B D Brandao, B Stainer, Rachel Thavayogan, D. Jones, Oluwatobi Onafowokan, A Gharooni, N Dabab, S Carlton-Carew, Garikai Kungwengwe, Melissa Gabriel, Emma Sewart, T Shortland, Samuel Lawday, Peter Pockney, Amanda Dawson, Peter Stewart, Benjamin Ng, Jason Luong, S Delibegovic, V. A. Ivanov, Anna V. Borisova, V Neykov, M Farkašová R Žebrák, J L Harbjerg, Søren Brandsborg, Anders Mark‐Christensen, K P Unbehaun, Peter Dalsgaard, Kathrine Dyhr Lycke, Aristotelis Kechagias, P LeNaoures, Émilie Duchalais, Cécile Brigand, E. Dumange, M Gout, C Moehwald, M Prem, Omar Alhalabi, S Sliwiński, Johannes Krupp, Eva Gablenz, L Schmitzer, A. Kopp, John G. Steinle, Julia Gsenger, L J Pohl, Mariagrazia Riccardi, I M Christodoulou, M. Konstantinidis, Nikolaos Machairas, Athanasios Zoikas, Dimitrios Balalis, Dimitrios K. Manatakis, M L Aguilera, Andrea Simioni, Luigi Marano, Francesco Fleres, Federico Lovisetto, Diego Sasia, Edoardo Segalini, Giacomo Pata, Andrea Lucchi, Andrea Sagnotta, Tommaso Campagnaro, Filippo Petrelli, Gaetano Gallo, Matteo Papandrea, Valentina Testa, Giovanni Sinibaldi, Francesca Di Candido, F. Colombo, Gennaro Perrone, S Aresu, Alessia Biancafarina, Giuseppe Canonico, Michele Pagnanelli, Gianluca Curletti, Roberto Bini, A De Manzoni Garberini, Harmony Impellizzeri, Nicola Cillara, Roberta Tutino, Arcangelo Picciariello, Diego Coletta, Gustavo Savino, Francesco Ferrara, Nicolò Tamini, Giuseppina Talamo, Dario Parini, P. Giamundo, Gennaro Pagano, V. Ripetti, Antonio Pesce, Nunzia Menduni, Gianluca Pellino, Rosina Giudicissi, Mauro Podda, Ehud Goldin, Daniela Rega, Antonio Belli, Valeria Andriola, Luca Gordini, Francesco Pata, Caterina Foppa, Gaetano Piccolo, Arianna Birindelli, Cecilia Ferrari, Zeno Ballarini, Flavio Tirelli, Marco Milone, Michele De Rosa, N S Pipitone Federico, Beatrice Molteni, Pier Luigi Tilocca, Giulio Sancini, Guglielmo Niccolò Piozzi, Andrea Lauretta, Silvia Mulas, V. Schaeff, Amy D. Otto, Matas Jakubauskas, Dainius Šimčikas, L Portelli, J. W. M. van Wijnbergen, T L Dinger, S. F. H. ten Doesschate, Anne Sophie H.M. van Dalen, D. D. van den Bos, Martin‐Leo Hansmann, J Medina Feliz, Sara Z. Kuiper, Ziena Abdulrahman, S R Pruijssers, V P Geneta, Michael J. J. Chu, Stephen B. Wilton, H Kandelaki, Shuang Peng, Simon Campbell, Yee-Wei Lim, Shahed Yassaie, Michael J. Murray, Paul Fagan, Cheyaanthan Haran, J Tan, João Pimenta de Castro, Álvaro Laranjeira, Susana O. Catarino, C Neves-Marques, J. G. Correia, Bárbara Vieira, Catarina Quintela, Marta Serra, J Maciel, Miguel F Cunha, David Aparício, José Farela Neves, José Azevedo, Manuela Romano, F Eiró, Joana Romano, Cristina Monteiro, M Claro, Almeida, Mariana Peyroteo, N D Machado, Hugo Capote, Margarida Ferreira, Xavier de Sousa, Helena Devesa, Demetrio Cavadas, I Guerreiro, Maria Laura Costa, Manuel Rosete, M Salman, C English, N Mohammed, S S Popescu, A Yanishev, Andrey Litvin, V Cuk, K Mészárosová, Stephanie Van Straten, Robert Jaich, Henrique Lima, Savannah Brooks, M. Marx, M Nshalati Salvation, Juan García Cardo, Ismael Mora‐Guzmán, Jorge Sancho Muriel, U De Andres Olabarria, Pablo Muriel, Clara Viñas, Felipe Alconchel, O Esteban Sinovas, Y. El Kasmy El Kasmi, C. Fairén Oro, S Pérez-Ajates, M. López Otero, S. Figueroa Jiménez, O. Claramonte Bellmunt, J Martínez Caballero,
Abstract Background Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function. Methods A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between ...
Oxford University Press
Produção Nacional
Revisado por pares
Luiz Cláudio Ferreira Romanelli, Débora Marques de Miranda, Anna Barbara F. Carneiro‐Proietti, Marcelo Mamede, Hérika Martins Mendes Vasconcelos, Marina Lobato Martins, Anísia S. D. Ferreira, Daniela Rosa, Jonas Jardim de Paula, Marco Aurélio Romano‐Silva, Rodrigo Nicolato,
Background HTLV-1 infection is endemic in Brazil. About 1 to 2% of the Brazilian population is estimated to be infected, but most infected HTLV-1 individuals do not know about their own infection, which favors the continuity of sexual and vertical virus transmission. In addition, HTLV-1 associated central nervous system diseases and their pathophysiologic mechanisms are not fully understood. This study aimed to evaluate the correlation of spinal cord metabolism, viral and inflammatory profiles with ...
Tópico(s): Animal Disease Management and Epidemiology
2018 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Danielle de Souza Costa, Jonas Jardim de Paula, Leandro Fernandes Malloy‐Diniz, Marco Aurélio Romano‐Silva, Débora Marques de Miranda,
To investigate the psychometric properties of the short or multimodal treatment study version of the Swanson, Nolan, and Pelham, Version IV (SNAP-IV) scale, which measures attention-deficit/hyperactivity disorder and oppositional defiant disorder symptoms.Participants were 765 parents of children from 4 to 16 years old (641 non-attention-deficit/hyperactivity disorder and 124 attention-deficit/hyperactivity disorder children) from Belo Horizonte, Brazil, who reported sociodemographic characteristics ...
Tópico(s): Functional Brain Connectivity Studies
2018 - Elsevier BV | Jornal de Pediatria
Produção Nacional
Revisado por pares
Jonas Jardim de Paula, Leandro Fernandes Malloy‐Diniz, Marco Aurélio Romano‐Silva,
Tópico(s): Psychological Testing and Assessment
2016 - Associação Brasileira de Psiquiatria | Brazilian Journal of Psychiatry
Produção Nacional
Revisado por pares
Patrícia de Araújo Pereira, Antônio Alvim-Soares, Valéria C. Sandrim, Carla Márcia Moreira Lanna, Débora C. Souza-Costa, Vanessa A. Belo, Jonas Jardim de Paula, José E. Tanus‐Santos, Marco Aurélio Romano‐Silva, Débora Marques de Miranda,
Obesity is a chronic disease caused by both environmental and genetic factors. Epidemiological studies have documented that increased energy intake and sedentary lifestyle, as well as a genetic contribution, are forces behind the obesity epidemic. Knowledge about the interaction between genetic and environmental components can facilitate the choice of the most effective and specific measures for the prevention of obesity. The aim of this study was to assess the association between the FTO, AKT1, ...
Tópico(s): Obesity, Physical Activity, Diet
2016 - Elsevier BV | Jornal de Pediatria
Produção Nacional
Revisado por pares
Leandro Fernandes Malloy‐Diniz, Guilherme Menezes Lage, Simone Becho Campos, Jonas Jardim de Paula, Danielle de Souza Costa, Marco Aurélio Romano‐Silva, Débora Marques de Miranda, Humberto Corrêa,
Impulsivity is a multidimensional construct which has been associated with dopaminergic neurotransmission. Nonetheless, until this moment, few studies addressed the relationship between different types of impulsivity and the single nucleotide polymorphism caused by a substitution of valine (val) with methionine (met) in the 158 codon of the Catechol-o-Methyltransferase gene (COMT-val158met). The present study aimed to investigate the association between val158met COMT polymorphism and impulsive behavior ...
Tópico(s): Autism Spectrum Disorder Research
2013 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Lorrayne Stephane Soares, Ana Luíza Costa Alves, Danielle de Souza Costa, Leandro Fernandes Malloy‐Diniz, Jonas Jardim de Paula, Marco Aurélio Romano‐Silva, Débora Marques de Miranda,
Introduction: Autism Spectrum Disorder (ASD) and Attention Deficit/Hyperactivity Disorder (ADHD) figures among the most common neurodevelopmental disorders. Despite having opposite stereotypes, both ADHD and ASD compromise, though in different ways, skills such as social interactions, communication skills, and social thinking, which may underlie difficulties in romantic relationships. Methods: We evaluated 306 adults about their romantic relationships and the intensity of their love. Participants ...
Tópico(s): Child and Adolescent Psychosocial and Emotional Development
2021 - Frontiers Media | Frontiers in Psychiatry
Produção Nacional
Revisado por pares
Débora Marques de Miranda, Daniela Rosa, Bruno Silva Costa, Nycolle Ferreira Nicolau, Luiz Alexandre Viana Magno, Jonas Jardim de Paula, Marco Aurélio Romano‐Silva,
Epilepsy affects about 1 % of the world population. Mesial temporal lobe epilepsy (mTLE) presents with seizures initiated in hippocampus and is the most frequent form of epilepsy. About 30 % of individuals with mTLE do not respond to conventional medications maintaining seizures and consequently new lesions on a daily basis. Treatment-resistant epilepsy has a huge social and individual burden due to impaired quality of life and increased mortality rate. There are many reasons for telomere shortening ...
Tópico(s): Trace Elements in Health
2020 - Elsevier BV | Epilepsy Research
Produção Nacional
Revisado por pares
Patrícia A. Pereira, Antônio Alvim-Soares, Maria Aparecida Camargos Bicalho, Edgar Nunes de Moraes, Leandro Fernandes Malloy‐Diniz, Jonas Jardim de Paula, Marco Aurélio Romano‐Silva, Débora Marques de Miranda,
Objectives: This study aims to evaluate the association between polymorphisms in circadian genes and Alzheimer's disease (AD) and/or late-onset depression (LOD). AD pathology leads to circadian disturbances, with clear negative influence on quality of life. In addition, there is an increasing evidence that regulators of circadian system have effects on AD and LOD pathology. Design and Subjects: An exploratory case-control study designed to evaluate SNPs in the PER2, PER3, CLOCK and OX2R genes in a ...
Tópico(s): Psychological and Temporal Perspectives Research
2016 - Bentham Science Publishers | Current Alzheimer Research
Produção Nacional
Revisado por pares
Sabrina de Sousa Magalhães, Diana Kraiser Miranda, Jonas Jardim de Paula, Débora Marques de Miranda, Marco Aurélio Romano‐Silva, Leandro Fernandes Malloy‐Diniz,
Background: Children and adolescents are considered a population at risk for developing posttraumatic stress disorder (PTSD) after a traumatic event. The Children's Revised Impact Scale (CRIES-8) is a self-report scale with 8 items that investigates avoidance and intrusion behaviors related to posttraumatic stress symptoms. Objective: The study consisted of translation and transcultural adaptation of CRIES-8 to Brazilian Portuguese and evaluation of its psychometric properties. Methods: A sample of ...
Tópico(s): Migration, Health and Trauma
2018 - UNIVERSIDADE DE SÃO PAULO | Archives of Clinical Psychiatry (São Paulo)
Produção Nacional
Revisado por pares
Jonas Jardim de Paula, Danielle de Souza Costa, Débora Marques de Miranda, Marco Aurélio Romano‐Silva,
Objective: Cognitive failures are simple mistakes in routine activities, such as forgetting commitments and experiencing difficulty concentrating. The Cognitive Failures Questionnaire (CFQ) was designed to assess the frequency of these errors in everyday life. Although widely used in psychiatry and psychology, both in clinical and research settings, it has not been adapted for use in Brazil. Our objective was to perform cross-cultural adaptation of the CFQ for the Brazilian reality and assess its ...
Tópico(s): Mind wandering and attention
2017 - Associação Brasileira de Psiquiatria | Brazilian Journal of Psychiatry
Produção Nacional
Revisado por pares
Danielle de Souza Costa, Jonas Jardim de Paula, Antônio M. Alvim-Soares Júnior, Breno S. Diniz, Marco Aurélio Romano‐Silva, Leandro Fernandes Malloy‐Diniz, Débora Marques de Miranda,
Fluid intelligence and the behavioral problems of attention-deficit/hyperactivity disorder (ADHD) are related to academic performance, but how this association occurs is unclear. This study aimed to assess mediation and moderation models that test possible pathways of influence between these factors.Sixty-two children with ADHD and 33 age-matched, typically developing students were evaluated with Raven's Colored Progressive Matrices and the spelling and arithmetic subtests of the Brazilian School ...
Tópico(s): Neural and Behavioral Psychology Studies
2014 - Associação Brasileira de Psiquiatria | Brazilian Journal of Psychiatry
Produção Nacional
Revisado por pares
Lorrayne Stephane Soares, Danielle de Souza Costa, Leandro Fernandes Malloy‐Diniz, Marco Aurélio Romano‐Silva, Jonas Jardim de Paula, Débora Marques de Miranda,
In this study, we proposed to investigate the association between infatuation/passionate love and impulsivity in a context of potential high impulsivity: adolescents with attention deficit and hyperactivity/impulsivity (ADHD) diagnosis compared with typically developing adolescents.Impulsivity was understood as an exploratory and a sensation seeking behavior, a trend to engage in novel and exciting activities, and was evaluated using the UPPS Impulsive Behavior Scale. Eighty-one adolescents from ...
Tópico(s): Obsessive-Compulsive Spectrum Disorders
2019 - Frontiers Media | Frontiers in Behavioral Neuroscience
Produção Nacional
Revisado por pares
Jonas Jardim de Paula, Maicon Rodrigues Albuquerque, Guilherme Menezes Lage, Maria Aparecida Camargos Bicalho, Marco Aurélio Romano‐Silva, Leandro Fernandes Malloy‐Diniz,
Cognitive impairment is a hallmark of mild cognitive impairment (MCI) and Alzheimer's disease dementia (AD). Although the cognitive profile of these patients and its association with activities of daily living (ADLs) is well documented, few studies have assessed deficits in fine motor dexterity and their association with ADL performance. The objective of this research paper is to evaluate fine motor dexterity performance among MCI and AD patients and to investigate its association with different aspects ...
Tópico(s): Alzheimer's disease research and treatments
2016 - Associação Brasileira de Psiquiatria | Brazilian Journal of Psychiatry
Produção Nacional
Revisado por pares
Jonas Jardim de Paula, Lafaiete Moreira, Rodrigo Nicolato, Luiz Armando De Marco, Humberto Corrêa, Marco Aurélio Romano‐Silva, Edgar Nunes de Moraes, Maria Aparecida Camargos Bicalho, Leandro Fernandes Malloy‐Diniz,
The Tower of London (TOL) is used for evaluating planning skills, which is a component of the executive functions. Different versions and scoring criteria were developed for this task, and some of them present with different psychometrical properties. This study aimed to evaluate two specific scoring methods of the TOL in diagnosing Mild Cognitive Impairment and probable Alzheimer's disease. The TOL total scores from 60 patients of each diagnosis were compared with the performance of 60 healthy-aged ...
Tópico(s): Alzheimer's disease research and treatments
2012 - SAGE Publishing | Psychological Reports
Jonas Jardim de Paula, Carlos Guilherme Schlottfeldt, Lafaiete Moreira, Mariana Cotta, Maria Aparecida Bicalho, Marco Aurélio Romano‐Silva, Humberto Corrêa, Edgar Nunes de Moraes, Leandro Fernandes Malloy‐Diniz,
CONTEXTO: O aumento na expectativa de vida e na proporção de idosos na população tem acarretado elevação nas taxas de prevalência de demências. O diagnóstico correto da demência é muito importante para o tratamento clínico e para um melhor prognóstico. Por isso, é necessário adaptar e desenvolver instrumentos para o diagnóstico diferencial entre os processos de envelhecimento normal e patológico. OBJETIVO: Avaliar as propriedades psicrométricas e a estrutura fatorial de um protocolo neuropsicológico ...
Tópico(s): Health Education and Validation
2010 - UNIVERSIDADE DE SÃO PAULO | Archives of Clinical Psychiatry (São Paulo)
Renata Maria Silva Santos, Samara de Alcântara Ventura, Yago Jean de Almeida Nogueira, Camila Guimarães Mendes, Jonas Jardim de Paula, Débora Marques de Miranda, Marco Aurélio Romano‐Silva,
Tópico(s): Eating Disorders and Behaviors
2024 - Springer Science+Business Media | Journal of Technology in Behavioral Science
Produção Nacional
Revisado por pares
Danielle de Souza Costa, Jonas Jardim de Paula, Nilton Alves de Rezende, Luiz Oswaldo Carneiro Rodrigues, Leandro Fernandes Malloy‐Diniz, Marco Aurélio Romano‐Silva, Débora Marques de Miranda,
Cognitive performance is compromised in Neurofibromatosis type 1 (NF1) patients, but neuropsychological data including elderly NF1 are extremely sparse. We compared the cognitive performance of a small elderly NF1 group (n = 5) with an age-matched healthy control group (n = 49). NF1 group performed worse than control group on a global cognitive impairment task, verbal working memory, and visuospatial functioning. The results suggest that cognitive impairment is an important feature of NF1 across lifespan, ...
Tópico(s): Vascular Malformations Diagnosis and Treatment
2014 - Elsevier BV | European Journal of Medical Genetics
Produção Nacional
Revisado por pares
Henrique Turin Moreira, Gustavo Jardim Volpe, José Antônio Marin‐Neto, Bharath Ambale‐Venkatesh, Chike C. Nwabuo, Henrique Simão Trad, Minna Moreira Dias Romano, Antônio Pazin‐Filho, Benedito Carlos Maciel, João A.C. Lima, André Schmidt,
Right ventricular (RV) impairment is postulated to be responsible for prominent systemic congestion in Chagas disease. However, occurrence of primary RV dysfunction in Chagas disease remains controversial. We aimed to study RV systolic function in patients with Chagas disease using cardiac magnetic resonance.This cross-sectional study included 158 individuals with chronic Chagas disease who underwent cardiac magnetic resonance. RV systolic dysfunction was defined as reduced RV ejection fraction based ...
Tópico(s): Viral Infections and Immunology Research
2017 - Lippincott Williams & Wilkins | Circulation Cardiovascular Imaging
Produção Nacional
Revisado por pares
Jonas Jardim de Paula, Maria Aparecida Camargos Bicalho, Rafaela Ávila, Marco Túlio Gualberto Cintra, Breno S. Diniz, Marco Aurélio Romano‐Silva, Leandro Fernandes Malloy‐Diniz,
Depressive symptoms are associated with cognitive-functional impairment in normal aging older adults (NA). However, less is known about this effect on people with mild Cognitive Impairment (MCI) and mild Alzheimer's disease dementia (AD). We investigated this relationship along with the NA-MCI-AD continuum by reanalyzing a previously published dataset. Participants (N = 274) underwent comprehensive neuropsychological assessment including measures of Executive Function, Language/Semantic Memory, Episodic ...
Tópico(s): Aging and Gerontology Research
2016 - Frontiers Media | Frontiers in Psychology
Produção Nacional
Revisado por pares
Pedro H. O. Passos, Daniel Ramos, Alessandro Romano, Karina Ribeiro Leite Jardim Cavalcante, Luisa Helena Monteiro de Miranda, Janice Mery Chicarino Coelho, Ramona C. Barros, Arnaldo Jorge Martins Filho, Juarez Antônio Simões Quaresma, Isabel Luana de Macêdo, Taís Meziara Wilson, Davi Emanuel Ribeiro de Sousa, Cristiano Barros de Melo, Márcio Botelho de Castro,
The early detection and diagnosis of deaths in free-ranging non-human primates (NHPs) are key points for the surveillance of Yellow Fever (YF) in Brazil. The histopathological identification of infectious diseases remains very useful and reliable in the screening and detection of emerging zoonotic diseases such as YF. We surveyed data records and liver slides stained with hematoxylin and eosin from the Epizootics Surveillance Network to control YF, Ministry of Health of Brazil, to evaluate histopathological ...
Tópico(s): Viral Infections and Outbreaks Research
2022 - Elsevier BV | Acta Tropica
Produção Nacional
Revisado por pares
Danielle de Souza Costa, Jonas Jardim de Paula, Leandro Fernandes Malloy‐Diniz, Marco Aurélio Romano‐Silva, Débora Marques de Miranda,
To investigate the psychometric properties of the short or multimodal treatment study version of the Swanson, Nolan, and Pelham, Version IV (SNAP‐IV) scale, which measures attention‐deficit/hyperactivity disorder and oppositional defiant disorder symptoms. Participants were 765 parents of children from 4 to 16 years old (641 non‐attention‐deficit/hyperactivity disorder and 124 attention‐deficit/hyperactivity disorder children) from Belo Horizonte, Brazil, who reported sociodemographic characteristics ...
Tópico(s): Child and Adolescent Psychosocial and Emotional Development
2019 - Elsevier BV | Jornal de Pediatria (Versão em Português)
Produção Nacional
Revisado por pares
Jonas Jardim de Paula, Breno S. Diniz, Maria Aparecida Camargos Bicalho, Maicon Rodrigues Albuquerque, Rodrigo Nicolato, Edgar Nunes de Moraes, Marco Aurélio Romano‐Silva, Leandro Fernandes Malloy‐Diniz,
Cognitive functioning play an important role in the performance of activities of daily living (ADL). Although and association between this two measures are usually reported in neuropsychological studies, the results are inconsistent, especially in what aspects cognitive functioning are more or less related to each functional aspect. In addition, only a few studies investigated if depressive symptoms are associated with worse functional performance in older adults. Our objective is to investigate ...
Tópico(s): Neural and Behavioral Psychology Studies
2015 - Frontiers Media | Frontiers in Aging Neuroscience