Fareeba Sheedfar, Miranda M. Sung, Marcela Aparicio-Vergara, Niels J. Kloosterhuis, María E. Miquilena-Colina, Javier Vargas‐Castrillón, Maria Febbraio, René L. Jacobs, Alain de Bruin, Manlio Vinciguerra, Carmelo Garcı́a-Monzón, Marten H. Hofker, Jason R.B. Dyck, Debby P.Y. Koonen,
... Aparicio-Vergara, Niels J Kloosterhuis, Maria Eugenia Miquilena-Colina, Javier Vargas-Castrillón, Maria Febbraio, René L Jacobs, Alain ...
Tópico(s): Diet, Metabolism, and Disease
2014 - Impact Journals LLC | Aging
Gema Frühbeck, Victoria Catalán, Amaia Rodrı́guez, Beatriz Ramírez, Sara Becerril, Javier Salvador, Inmaculada Colina, Javier Gómez‐Ambrosi,
Obesity favors the development of cardiometabolic alterations such as type 2 diabetes (T2D) and the metabolic syndrome (MS). Obesity and the MS are distinguished by an increase in circulating leptin concentrations, in parallel to a drop in the levels of adiponectin. Consequently, the Adpn/Lep ratio has been suggested as a maker of dysfunctional adipose tissue. We aimed to investigate in humans (n = 292) the reliability of the Adpn/Lep ratio as a biomarker of adipose tissue dysfunction. We considered ...
Tópico(s): Adipose Tissue and Metabolism
2019 - Multidisciplinary Digital Publishing Institute | Nutrients
Gema Frühbeck, Victoria Catalán, Amaia Rodrı́guez, Beatriz Ramírez, Sara Becerril, Javier Salvador, Piero Portincasa, Inmaculada Colina, Javier Gómez‐Ambrosi,
The aim of the present work was to study whether the leptin-adiponectin axis may have a pathophysiological role in the increased systemic inflammation and oxidative stress observed in patients with the metabolic syndrome (MS). Leptin, adiponectin, and markers of inflammation and oxidative stress were measured in a sample of 140 Caucasian subjects (74 males/66 females), aged 28-82 years, 60 with and 80 without the MS. Total concentrations of adiponectin as well as its multimeric forms HMW, MMW and ...
Tópico(s): Adipose Tissue and Metabolism
2017 - Nature Portfolio | Scientific Reports
Bjorn Emonts, L. Colina, Javier Piqueras López, S. García‐Burillo, M. Pereira-Santaella, S. Arribas, Á. Labiano, A. Alonso‐Herrero,
We present the detection and morphological characterization of hot molecular gas outflows in nearby ultra-luminous infrared galaxies (ULIRGs), using the Spectrograph for Integral Field Observations in the Near Infrared (SINFONI) on the Very Large Telescope (VLT). We detect outflows observed in the 2.12 μm H2 1–0 S(1) line for three out of four ULIRGs that we analyzed, namely IRAS 12112+0305, IRAS 14348-1447, and IRAS 22491-1808. The outflows are mapped on scales of 0.7−1.6 kpc, show typical outflow ...
Tópico(s): Astrophysical Phenomena and Observations
2017 - EDP Sciences | Astronomy and Astrophysics
Produção Nacional
Revisado por pares
L. Colina, Javier Piqueras López, S. Arribas, Rogério Riffel, Rogemar A. Riffel, A. Rodríguez-Ardila, M. G. Pastoriza, Thaisa Storchi‐Bergmann, A. Alonso‐Herrero, Dinalva A. Sales,
We investigate the two-dimensional excitation structure of the interstellar medium (ISM) in a sample of luminous infrared galaxies (LIRGs) and Seyferts using near-IR integral field spectroscopy. This study extends to the near infrared the well-known optical and mid-IR emission line diagnostics used to classify activity in galaxies. Based on the spatially resolved spectroscopy of prototypes, we identify in the [FeII]1.64 μm/Brγ− H22.12 μm/Brγ plane regions dominated by the different heating sources, ...
Tópico(s): Gamma-ray bursts and supernovae
2015 - EDP Sciences | Astronomy and Astrophysics
Águeda González‐Rodríguez, Rafael Mayoral, Néstor Vázquez-Agra, M. Pilar Valdecantos, Virginia Pardo, María E. Miquilena-Colina, Javier Vargas‐Castrillón, Oreste Lo Iacono, Marco Corazzari, Gian María Fimia, Mauro Piacentini, Jordi Muntané, Lisardo Boscá, Carmelo Garcı́a-Monzón, Paloma Martín‐Sanz, Ángela M. Valverde,
The pathogenic mechanisms underlying the progression of non-alcoholic fatty liver disease (NAFLD) are not fully understood. In this study, we aimed to assess the relationship between endoplasmic reticulum (ER) stress and autophagy in human and mouse hepatocytes during NAFLD. ER stress and autophagy markers were analyzed in livers from patients with biopsy-proven non-alcoholic steatosis (NAS) or non-alcoholic steatohepatitis (NASH) compared with livers from subjects with histologically normal liver, ...
Tópico(s): Liver Disease Diagnosis and Treatment
2014 - Springer Nature | Cell Death and Disease
S. Cazzoli, S. Arribas, L. Colina, Javier Piqueras López, E. Bellocchi, Bjorn Emonts, R. Maiolino,
We present a multi-wavelength integral field spectroscopic (IFS) study of the low-z luminous infrared galaxy IRAS F11506-3851 (ESO 320-G030) on the basis of the moderate spectral resolution observations (R ~ 3400−4000) taken with the VIMOS and SINFONI instruments at the ESO VLT. The morphology and the 2D kinematics of the gaseous (neutral and ionized) and stellar components have been mapped in the central regions (<3 kpc) using the NaDλλ5890, 5896 Å absorption doublet, the Hαλ6563 Å line, and the near-IR ...
Tópico(s): Stellar, planetary, and galactic studies
2014 - EDP Sciences | Astronomy and Astrophysics
M. Cotarelo, J.M. Guerra-Vales, Francisco Colina, Javier de la Cruz,
Aims and background Patients with cancer of an unknown primary site (CUP) usually have a poor outcome. The identification of prognostic factors that affect survival can help clinicians find a better approach to such cases in terms of diagnostic and therapeutic management. Methods We conducted a retrospective study including the cases of CUP recorded at the University Hospital 12 de Octubre Tumor Registry between 1999 and 2003. Results CUP was diagnosed in 265 patients during the analyzed period. ...
Tópico(s): Oral and Maxillofacial Pathology
2010 - SAGE Publishing | Tumori Journal
Elena Lima‐Cabello, María Victoria García‐Mediavilla, María E. Miquilena-Colina, Javier Vargas‐Castrillón, Tamara Lozano-Rodríguez, Miguel Fernández‐Bermejo, J.L. Olcoz, Javier González‐Gallego, Carmelo Garcı́a-Monzón, Sonia Sánchez‐Campos,
NAFLD (non-alcoholic fatty liver disease) is one of the most frequent chronic liver diseases worldwide. The metabolic factors associated with NAFLD are also determinants of liver disease progression in chronic HCV (hepatitis C virus) infection. It has been reported that, besides inducing hepatic fatty acid biosynthesis, LXR (liver X receptor) regulates a set of inflammatory genes. We aimed to evaluate the hepatic expression of LXRα and its lipogenic and inflammatory targets in 43 patients with NAFLD, ...
Tópico(s): Hepatitis C virus research
2010 - Portland Press | Clinical Science
Cristina Natal, Patricia Restituto, C. Iñigo, Inmaculada Colina, Javier Dı́ez, Nerea Varo,
We hypothesized that the CD40/CD40 ligand (CD40L) system is up-regulated in the metabolic syndrome (MS) and modulated by adiponectin (AN). The objectives were: 1) to compare plasma and monocyte CD40L in patients with MS and controls and its association with clinical and biochemical parameters, 2) to investigate platelets as a source of soluble CD40L (sCD40L), and 3) to analyze the effects of AN on CD40/CD40L.Plasma sCD40L and AN were measured in 246 controls and 128 patients with MS by ELISA. Monocyte ...
Tópico(s): Biomarkers in Disease Mechanisms
2008 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
Cristina Natal, María Antonia Fortuño, Patricia Restituto, Antonio Bazán, Immaculada Colina, Javier Dı́ez, Nerea Varo,
Adipose tissue is a target for cardiotrophin-1 (CT-1), a cytokine member of the IL-6 family of cytokines that is involved in cardiac growth and dysfunction. However, it is unknown whether adipocytes are a source of CT-1 and whether CT-1 is overexpressed in diseases characterized by increased fat depots [i.e., the metabolic syndrome (MS)]. Thus this work aimed 1) to test whether adipose tissue expresses CT-1 and whether CT-1 expression can be modulated and 2) to compare serum CT-1 levels in subjects ...
Tópico(s): NF-κB Signaling Pathways
2007 - American Physiological Society | AJP Endocrinology and Metabolism
José A. Páramo, Óscar Beloqui, I. Colina, Javier Dı́ez, Josune Orbe,
Von Willebrand factor (VWF) is considered a reliable marker of endothelial damage. Plasma levels of VWF were measured in 857 middle-aged subjects (80.4% men) free of clinically overt atherosclerotic disease, in relation to cardiovascular risk factors, carotid intima-media thickness (IMT) and microalbuminuria, two established surrogate markers of atherosclerosis. There was linear trend for the increase of VWF, carotid IMT (p < 0.001) and microalbuminuria (p = 0.018). The association between VEF and both markers ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2005 - Elsevier BV | Journal of Thrombosis and Haemostasis
Rosa E. Cardoza, Santiago Gutiérrez, Nieves Ortega, Angel J. Colina, Javier Casqueiro, Juan F. Martı́n,
Abstract A copy of the bovine chymosin gene ( chy ) with a codon usage optimized for its expression in Aspergillus awamori was constructed starting from synthetic oligonucleotides. To study the ability of this filamentous fungus to secrete bovine prochymosin, two plasmids were constructed in which the transcriptional, translational, and secretory control regions of the A. nidulans gpd A gene and pep B genes were coupled to either preprochymosin or prochymosin genes. Secretion of a protein enzymatically ...
Tópico(s): Plant Reproductive Biology
2003 - Wiley | Biotechnology and Bioengineering
Produção Nacional
Revisado por pares
Cecília Patrícia Popolin, João P. B. Reis, Amanda Blanque Becceneri, Angélica E. Graminha, M. Almeida, Rodrigo S. Corrêa, Legna Colina‐Vegas, Javier Ellena, Alzir A. Batista, Márcia R. Cominetti,
Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype. The high rate of metastasis associated to the fact that these cells frequently display multidrug resistance, make the treatment of metastatic disease difficult. Development of antitumor metal-based drugs was started with the discovery of cisplatin, however, the severe side effects represent a limitation for its clinical use. Ruthenium (Ru) complexes with different ligands have been successfully studied as prospective ...
Tópico(s): Click Chemistry and Applications
2017 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Angélica E. Graminha, Cecília Patrícia Popolin, João Honorato, Rodrigo S. Corrêa, Katia M. Oliveira, Luani Rezende Godoy, Legna Colina‐Vegas, Javier Ellena, Alzir A. Batista, Márcia R. Cominetti,
In this work we present the synthesis and characterization of six new ruthenium compounds with general formulae [Ru(L)(dppb)(bipy)]PF6 and [Ru(L)(dppe)2]PF6 where L = salicylic acid (Sal), 4-aminosalicylic acid (AmSal) or 2,4-dihydroxybenzoic acid (DiSal), dppb = 1,4-bis(diphenylphosphino)butane, dppe = 1,2-bis(diphenylphosphino)ethane and bipy = 2,2'-bipyridine. The complexes were characterized by elemental analysis, molar conductivity, cyclic voltammetry, NMR, UV-vis and IR spectroscopies, and two by X-ray ...
Tópico(s): Ferrocene Chemistry and Applications
2022 - Elsevier BV | European Journal of Medicinal Chemistry
Abraham Monteón-Ojeda, J.A. Aguilera, Ángel Villegas-Monter, Cristian Nava Díaz, Elías Hernández Castro, Gabriel Otero-Colina, Javier Hernández Morales,
The temporal progress of anthracnose (Colletotrichum gloeosporioides) epidemics was studied in mango (Mangifera indica) orchards treated with fungicides from different chemical groups, mode of action, and application sequences in two regions of contrasting climates (sub-humid and dry tropics) in Guerrero, Mexico. Full flowering, initial setting, and 8-15mm Ø fruits were identified as critical stages for infection. Epidemics started 20-26 days after swollen buds, and maximum severity was attained at ...
Tópico(s): Plant Physiology and Cultivation Studies
2012 - Springer Science+Business Media | Tropical Plant Pathology
María-Antonia Martínez-Momblán, Javier Colina-Torralva, Laura de la Cueva‐Ariza, Eva Maria Guix‐Comellas, Marta Romero‐García, Pilar Delgado‐Hito,
Objective: to analyze the student’s progression in the acquisition of specific and transversal competences in relation to the competence dimensions. Method: the cross-sectional descriptive study was carried out in the clinical practice subjects included in the Nursing Degree. We included 323 students and we contemplated the development of competences through an ad-hoc questionnaire with 4 dimensions: delivery and care management, therapeutic communication, professional development and care management. ...
Tópico(s): Nursing Diagnosis and Documentation
2020 - UNIVERSIDADE DE SÃO PAULO | Revista Latino-Americana de Enfermagem
Produção Nacional
Revisado por pares
R. Marques-Chaves, I. Pérez-Fournón, Y. Shu, L. Colina, A. Bolton, Javier Álvarez-Márquez, Joel R. Brownstein, Matthew Cornachione, S. Geier, C Jiménez-Ángel, Takashi Kojima, Shude Mao, Antonio D. Montero-Dorta, Masamune Oguri, Masami Ouchi, F. Poidevin, R. Shirley, Zheng Zheng,
ABSTRACT We present deep rest-frame UV spectroscopic observations using the Gran Telescopio Canarias of six gravitationally lensed Lyα emitters (LAEs) at 2.36 < z < 2.82 selected from the BELLS GALLERY survey. By taking the magnifications into account, we show that LAEs can be as luminous as LLyα ≃ 30 × 1042 erg s−1 and MUV ≃ −23 (AB) without invoking an AGN component, in contrast with previous findings. We measure Lyα rest-frame equivalent widths, $EW_{0}\,\rm (Ly\alpha)$, ranging from 16 to 50 Å and ...
Tópico(s): Astrophysical Phenomena and Observations
2019 - Oxford University Press | Monthly Notices of the Royal Astronomical Society
Óscar Beloqui, José A. Páramo, Josune Orbe, Alberto Benito, Inmaculada Colina, Alberto Monasterio, Javier Dı́ez,
Aims Cyclooxygenase-2 (COX-2)-mediated prostaglandin production by activated macrophages is associated with inflammation and atherosclerosis. We investigated the relationship between COX-2-mediated prostaglandin-E2 (PGE2) release, cardiovascular risk factors, and carotid atherosclerosis in apparently healthy subjects. Methods and results PGE2 release by lipopolysaccharide-stimulated blood monocytes was measured by ELISA in 291 subjects (76.5% men, mean age 58) who underwent global vascular risk assessment ...
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2004 - Oxford University Press | European Heart Journal
Sarah E. I. Bosman, Javier Álvarez-Márquez, L. Colina, Fabian Walter, A. Alonso‐Herrero, M. J. Ward, Göran Östlin, T. R. Greve, Gillian Wright, A. Bik, Leindert Boogaard, K. I. Caputi, Luca Costantin, A. Eckart, M. García-Marín, Steven Gillman, J. Hjorth, Edoardo Iani, O. Ilbert, Iris Jermann, Á. Labiano, Danial Langeroodi, Florian Peißker, Pierluigi Rinaldi, M. Topinka, P. van der Werf, M. Güdel, Thomas Henning, Pierre-Olivier Lagage, T. P. Ray, E. F. van Dishoeck, B. Vandenbussche,
Tópico(s): Gamma-ray bursts and supernovae
2024 - Nature Portfolio | Nature Astronomy
Javier Álvarez-Márquez, L. Colina, A. Crespo Gómez, Pierluigi Rinaldi, Jens Melinder, G. Östlin, Marianna Annunziatella, Á. Labiano, A. Bik, S. Bosman, T. R. Greve, G. Wright, A. Alonso‐Herrero, Leindert Boogaard, R. Azollini, K. I. Caputi, Luca Costantin, A. Eckart, M. García-Marín, Steven Gillman, J. Hjorth, Edoardo Iani, O. Ilbert, Iris Jermann, Danial Langeroodi, R. A. Meyer, Florian Peißker, Pablo G. Pérez‐González, J. P. Pye, Tuomo Tikkanen, M. Topinka, P. van der Werf, Fabian Walter, Th. Henning, T. P. Ray,
We present MIRI/JWST medium-resolution spectroscopy (MRS) and imaging (MIRIM) of the lensed galaxy MACS1149-JD1 at a redshift of z = 9.1092 ± 0.0002, when the Universe was about 530 Myr old. We detect, for the first time, spatially resolved H α emission in a galaxy at a redshift above nine. The structure of the H α emitting gas consists of two clumps, S and N, carrying about 60% and 40% of the total flux, respectively. The total H α luminosity implies an instantaneous star-formation rate in the range ...
Tópico(s): Stellar, planetary, and galactic studies
2024 - EDP Sciences | Astronomy and Astrophysics
Macarena Muñoz, Samuel Cirés, Zahara M. de Pedro, José Ángel Colina, Yineth Velásquez-Figueroa, Javier Carmona-Jiménez, Ángela Caro-Borrero, Anthony Salazar, Mónica-Cecilia Santa María Fuster, David Contreras, Elvira Perona, Antonio Quesada, José A. Casas,
The increasing occurrence of cyanobacterial blooms worldwide represents an important threat for both the environment and public health. In this context, the development of risk analysis and management tools as well as sustainable and cost-effective treatment processes is essential. The research project TALGENTOX, funded by the Ibero-American Science and Technology Program for Development (CYTED-2019), aims to address this ambitious challenge in countries with different environmental and social conditions ...
Tópico(s): Water Quality and Pollution Assessment
2020 - Elsevier BV | The Science of The Total Environment
Produção Nacional
Revisado por pares
Rogemar A. Riffel, L. Colina, Thaisa Storchi‐Bergmann, Javier Piqueras López, S. Arribas, Rogério Riffel, M. G. Pastoriza, Dinalva A. Sales, N. Z. Dametto, Á. Labiano, R. Davies,
We present new maps of emission-line flux distributions and kinematics in both ionized (traced by H i and [Fe ii] lines) and molecular (H2) gas of the inner 0.7 × 0.7 kpc2 of the galaxy NGC 4303, with a spatial resolution 40–80 pc and velocity resolution 90–150 km s− 1 obtained from near-IR integral field spectroscopy using the Very Large Telescope instrument SINFONI. The most prominent feature is a 200–250 pc ring of circumnuclear star-forming regions. The emission from ionized and molecular gas shows ...
Tópico(s): Stellar, planetary, and galactic studies
2016 - Oxford University Press | Monthly Notices of the Royal Astronomical Society
José A. Páramo, Josune Orbe, Óscar Beloqui, Alberto Benito, I. Colina, Eduardo Martínez‐Vila, Javier Dı́ez,
Thrombin, a central enzyme in the clotting cascade, plays a role not only in thrombosis but also in the progression of atherosclerosis. We studied the relationship between prothrombin fragment 1+2 (F1+2), a specific marker of thrombin generation in vivo, and carotid intima-media thickness (IMT), an index of subclinical atherosclerosis.We examined 181 asymptomatic middle-aged subjects (mean age 55.6 years, 76.7% men) free of overt clinical atherosclerotic disease. F1+2 was measured by enzyme-linked ...
Tópico(s): Blood properties and coagulation
2004 - Lippincott Williams & Wilkins | Stroke
Produção Nacional
Revisado por pares
Wanessa Carvalho Pires, Benedicto Augusto Vieira Lima, Flávia de Castro Pereira, Aliny Pereira de Lima, Francyelli Mello-Andrade, Hugo D. Silva, Monize Martins da Silva, Legna Colina‐Vegas, Javier Ellena, Alzir A. Batista, Elisângela de Paula Silveira-Lacerda,
The aim of this work was the synthesis, characterization, and cytotoxicity evaluation of three new Ru(II) complexes with a general formula [Ru(Spy)(bipy)(P-P)]PF6 [Spy = pyridine-6-thiolate; bipy = 2,2'-bipyridine; P-P = 1,2-bis(diphenylphosphine)ethane (1); 1,3-bis(diphenylphosphine) propane (2); and 1,1'-bis(diphenylphosphino)ferrocene] (4). Complex (3) with the 1,4-bis(diphenylphosphine)butane ligand, already known from the literature, was also synthesized, to be better studied here. The cytotoxicities of ...
Tópico(s): Synthesis and Characterization of Heterocyclic Compounds
2017 - Springer Science+Business Media | Molecular and Cellular Biochemistry
Eva M. Fernández-Sáez, Maite Losarcos, Sara Becerril, Víctor Valentí, Rafael Moncada, Marina Martín, Marı́a A. Burrell, Victoria Catalán, Javier Gómez‐Ambrosi, Carmen Mugueta, Inmaculada Colina, Camilo Silva, Javier Escalada, Gema Frühbeck, Amaia Rodrı́guez,
The biological mediators supporting the resolution of liver steatosis, inflammation and fibrosis after bariatric surgery in patients with obesity and NAFLD remain unclear. We sought to analyze whether uroguanylin and guanylin, two gut hormones involved in the regulation of satiety, food preference and adiposity, are involved in the amelioration of obesity-associated NAFLD after bariatric surgery.Proguanylin (GUCA2A) and prouroguanylin (GUCA2B) were measured in 214 participants undergoing bariatric ...
Tópico(s): Diet, Metabolism, and Disease
2023 - Elsevier BV | Metabolism
Miguel Aller Pellitero, Álvaro Colina, Rosa Villa, F. Javier del Campo,
Spectroelectrochemistry studies spectral changes as a function of applied potential or current. While there is no standard experimental setup, transparent electrodes are most typically used in transmission mode. Working in reflection mode forces light across the sample twice, resulting in higher sensitivities, but in turn requires the use of highly reflective electrodes. Here we present the production and characterization of screen-printed electrodes made from different antimony tin oxide (ATO) conducting ...
Tópico(s): Conducting polymers and applications
2018 - Elsevier BV | Electrochemistry Communications
Produção Nacional
Revisado por pares
Gabriel H. Ribeiro, Legna Colina‐Vegas, Juan C. Tenório, Javier Ellena, Márcia R. Cominetti, Alzir A. Batista,
The rational design of anticancer agents that acts in specific biological targets is one of the most effective strategies for developing chemotherapeutic agents. Aiming at obtaining new ruthenium (II) compounds with good cytotoxicity against tumor cells, a series of new complexes of general formula [RuCl(PPh3)(Hdpa)(NN)]Cl [PPh3 = triphenylphosphine, N-N = 2,2'-dipyridylamine (Hdpa) (1), 1,2-diaminoethane (en) (2), 2,2'-bipyridine (bipy) (3), 5,5'-dimethyl-2,2'-bipyridine (dmbipy) (4), 1,10-phenanthroline (phen) ( ...
Tópico(s): Magnetism in coordination complexes
2019 - Elsevier BV | Journal of Inorganic Biochemistry
Produção Nacional
Revisado por pares
N. Z. Dametto, Rogério Riffel, L. Colina, Rogemar A. Riffel, Javier Piqueras López, R. Davies, L. Burtscher, R. B. Menezes, S. Arribas, M. G. Pastoriza, Á. Labiano, Thaisa Storchi‐Bergmann, L G Dahmer-Hahn, Dinalva A. Sales,
We present a spatially resolved stellar population study of the inner $\sim$200\,pc radius of NGC4303 based on near-infrared integral field spectroscopy with SINFONI/VLT at a spatial resolution of 40-80pc and using the STARLIGHT code. We found the distribution of the stellar populations presents a spatial variation, suggesting an age stratification. Three main structures stand out. Two nuclear blobs, one composed by young stars (t $\leq$ 50Myr) and one with intermediate-age stars (50Myr $$ 2Gyr) is distributed ...
Tópico(s): Astrophysical Phenomena and Observations
2018 - Oxford University Press | Monthly Notices of the Royal Astronomical Society
José Perea, Yolanda Rodríguez, Daniel Rueda, José Carlos Marín-Gabriel, José Díaz-Tasende, Edurne Álvaro, C. Alegre, Irene Osorio, Francisco Colina, Manuel Lomas, Manuel Hidalgo, Javier Benı́tez, Miguel Urioste,
Tópico(s): Colorectal and Anal Carcinomas
2011 - Springer Science+Business Media | Annals of Surgical Oncology