Pedro L. Valenzuela, Alejandro Santos‐Lozano, Javier S. Morales, Susana López‐Ortiz, José Pinto-Fraga, Adrián Castillo‐García, Juan Manuel Barroso y Martín, Julián Pérez-Villacastı́n, Araceli Boraíta, Alejandro Lucía,
... author on: Oxford Academic Google Scholar Javier S Morales, Javier S Morales Faculty of Sport Sciences, Universidad Europea de Madrid, ...
Tópico(s): Cardiac pacing and defibrillation studies
2020 - Oxford University Press | European Journal of Preventive Cardiology
Yehuda Handelsman, Javed Butler, George L. Bakris, Ralph A. DeFronzo, Gregg C. Fonarow, Jennifer B. Green, George Grunberger, James L. Januzzi, Samuel Klein, Pamela Kushner, Darren K. McGuire, Erin D. Michos, Javier Morales, Richard E. Pratley, Matthew R. Weir, Eugene E. Wright, Vivian Fonseca,
Increasing rates of obesity and diabetes have driven corresponding increases in related cardiorenal and metabolic diseases. In many patients, these conditions occur together, further increasing morbidity and mortality risks to the individual. Yet all too often, the risk factors for these disorders are not addressed promptly in clinical practice, leading to irreversible pathologic progression. To address this gap, we convened a Task Force of experts in cardiology, nephrology, endocrinology, and primary ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2023 - Elsevier BV | Journal of Diabetes and its Complications
Javier Morales, Yehuda Handelsman,
Chronic kidney disease (CKD) and cardiovascular disease (CVD) have a significant inter-relationship in patients with diabetes. Controlling blood pressure, dyslipidemia, and glucose levels is a common treatment approach to managing CVD risk in patients with CKD and diabetes; despite strict control, however, a high residual risk remains. This review focuses on patients who require pharmacotherapy, in whom new and existing cardiorenal therapies (renin-angiotensin-aldosterone system inhibitors, sodium- ...
Tópico(s): Heart Failure Treatment and Management
2023 - Elsevier BV | Journal of the American College of Cardiology
Morales Cabrera Mercedes, Hernaacute ndez Morales Javier, Leyva Ruacute elas Gabriel, Yol, Salinas Moreno a, Soto Rojas L, Castro Rosas Javier,
An analysis was done on the antimicrobial activity of calyx extracts from five Hibiscussabdariffa varieties against Salmonella typhimurium and Salmonella choleraesuis. Calyx extracts produced with water, ethanol and methanol were applied to Salmonella cultures. All extracts exhibited antimicrobial activity against both Salmonella serotypes. The antimicrobial effect was highest in the variety named as "Alma blanca" (in which anthocyanin production has been almost completely suppressed). Extract pH ...
Tópico(s): Phytochemicals and Antioxidant Activities
2013 - Academic Journals | Journal of Medicinal Plants Research
Pedro L. Valenzuela, Javier S. Morales, Alejandro Santos‐Lozano, Gonzalo Saco‐Ledo, Leonel Díaz-González, Araceli Boraíta, Carl J. Lavie, Alejandro Lucía,
... author on: Oxford Academic Google Scholar Javier S Morales, Javier S Morales Fissac—Physiology, Health and Physical Activity, Madrid, Spain ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2021 - Oxford University Press | European Journal of Preventive Cardiology
Javier Morales, Karina Valdés, Javier Morales, Felipe Oyarzún-Ampuero,
Retinoids are lipophilic compounds that are highly used in cosmetics/therapeutics for skin disorders. Conventional formulations are limited by poor water solubility, high chemical/photochemical instability and the irritation of retinoids. Interestingly, lipid nanoparticles enable the administration of retinoids in aqueous media, providing drug stabilization and controlled release. Recently, it has been demonstrated that retinoids in solid lipid nanoparticles, nanostructured lipid carriers, nanoemulsions ...
Tópico(s): Essential Oils and Antimicrobial Activity
2015 - Future Medicine | Nanomedicine
Layla Fernández, Layla Fernández, Óscar Bañuelos, Alberto Zafra‐Gómez, C. Ronchel, Ignacio Pérez‐Victoria, Juan Carlos Morales, Layla Fernández, Óscar Bañuelos, Alberto Zafra‐Gómez, C. Ronchel, Ignacio Pérez‐Victoria, Juan Carlos Morales, Javier Velasco, Layla Fernández, Óscar Bañuelos, Alberto Zafra‐Gómez, C. Ronchel, Ignacio Pérez‐Victoria, Juan Carlos Morales, Javier Velasco, José L. Adrio,
One cycle of random mutagenesis and screening of an expression mutant library in P. pastoris was used to isolate two variants of Galactomyces geotrichum BT107 lipase I showing a 2-fold reduction in their hydrolytic activity towards the homogeneous triglyceride of eicosapentaenoic acid (triEPA, C20:5 n-3) compared with the wild-type enzyme. Only one amino acid substitution on each variant was enough to decrease their activity on this polyunsaturated substrate. The activity of the enzyme for triglycerides ...
Tópico(s): Lipid metabolism and biosynthesis
2008 - Taylor & Francis | Biocatalysis and Biotransformation
Julián Bejarano, Mario Navarro-Márquez, Francisco Morales-Zavala, Javier Morales, Ivonne García‐Carvajal, Eyleen Araya, Yvo Flores, Hugo Verdejo, Pablo Castro, Sergio Lavandero, Marcelo J. Kogan,
Cardiovascular diseases are the leading cause of death worldwide. Despite preventive efforts, early detection of atherosclerosis, the common pathophysiological mechanism underlying cardiovascular diseases remains elusive, and overt coronary artery disease or myocardial infarction is often the first clinical manifestation. Nanoparticles represent a novel strategy for prevention, diagnosis, and treatment of atherosclerosis, and new multifunctional nanoparticles with combined diagnostic and therapeutic ...
Tópico(s): Protease and Inhibitor Mechanisms
2018 - Ivyspring International Publisher | Theranostics
Javier Morales Sarriera, Gonzalo Araya, Tomás Serebrisky, Cecilia Briceño-Garmendía, Jordan Schwartz,
... and the Caribbean: A Stochastic Frontier AnalysisAuthors/Editors: Javier Morales Sarriera, Gonzalo Araya, Tomas Serebrisky, Cecilia Briceño-Garmendía, ...
Tópico(s): Urban and Freight Transport Logistics
2013 - | World Bank policy research working paper
Ana Otero, Digna Garcı́a, Ever Morales, Javier Arán, Jaime Fábregas,
... papers by this authorEver D. Morales, Ever D. Morales Departamento de Microbiología, Facultad de Farmacia, Universidad de Santiago, Santiago 15706, SpainSearch for more papers by this authorJavier Arán, Javier Arán Departamento de Microbiología, Facultad de Farmacia, Universidad ... papers by this authorEver D. Morales, Ever D. Morales Departamento de Microbiología, Facultad de Farmacia, Universidad de Santiago, Santiago 15706, SpainSearch for more papers by this authorJavier Arán, Javier Arán Departamento de Microbiología, Facultad de Farmacia, Universidad ...
Tópico(s): Transgenic Plants and Applications
1997 - Wiley | Biotechnology and Applied Biochemistry
Javier Hernandez‐Ortega, Julián Fiérrez, Aythami Morales, Javier Galbally,
The main scope of this chapter is to serve as a brief introduction to face presentation attack detection. The next pages present the different presentation attacks that a face recognition system can confront, in which an attacker presents to the sensor, mainly a camera, an artifact (generally a photograph, a video, or a mask) to try to impersonate a genuine user. First, we make an introduction of the current status of face recognition, its level of deployment, and the challenges it faces. In addition, ...
Tópico(s): Face and Expression Recognition
2019 - Springer International Publishing | Advances in computer vision and pattern recognition
Javier Fernández‐Torres, Cristina Hernández‐Díaz, Rolando Espinosa-Morales, Javier Camacho-Galindo, Norma Galindo-Sevilla, Ambar López‐Macay, Yessica Zamudio‐Cuevas, Karina Martínez‐Flores, Mónica Santamaría‐Olmedo, Carlos Pineda, Julio Granados, Gabriela Angélica Martínez‐Nava, Marwin Gutiérrez, Alberto López-Reyes,
Osteoarthritis (OA) is a multifactorial degenerative condition of the whole joint with a complex pathogenesis whose development and progression is significantly mediated by interactions between the joint cartilage and articular tissues, particularly, proinflammatory mediators and oxidative stress, which results in cartilage deterioration and subchondral bone destruction. HIF-1 alpha regulates oxygen homeostasis in hypoxic tissues such as joint cartilage; efficiency of transcriptional activity of ...
Tópico(s): Knee injuries and reconstruction techniques
2015 - BioMed Central | BMC Musculoskeletal Disorders
Yehuda Handelsman, John E. Anderson, George L. Bakris, Christie M. Ballantyne, Deepak L. Bhatt, Zachary T. Bloomgarden, Biykem Bozkurt, Matthew J. Budoff, Javed Butler, David Z.I. Cherney, Ralph A. DeFronzo, Stefano Del Prato, Robert H. Eckel, Gerasimos Filippatos, Gregg C. Fonarow, Vivian A. Fonseca, W. Timothy Garvey, Francesco Giorgino, Peter J Grant, Jennifer B. Green, Stephen J Greene, Per-Henrik Groop, George Grunberger, Ania M. Jastreboff, Paul S. Jellinger, Kamlesh Khunti, Samuel Klein, Mikhail Kosiborod, Pamela Kushner, Lawrence A. Leiter, Norman E. Lepor, Christos S. Mantzoros, Chantal Mathieu, Christian W. Mende, Erin D. Michos, Javier Morales, Jorge Plutzky, Richard E. Pratley, Kausik K Ray, Peter Rossing, Naveed Sattar, Peter E.H. Schwarz, Eberhard Standl, Philippe Gabríel Steg, Lâle Tokgözoğlu, Jaakko Tuomilehto, Guillermo E Umpierrez, Paul Valensi, Matthew R. Weir, John Wilding, Eugene E. Wright,
The spectrum of cardiorenal and metabolic diseases comprises many disorders, including obesity, type 2 diabetes (T2D), chronic kidney disease (CKD), atherosclerotic cardiovascular disease (ASCVD), heart failure (HF), dyslipidemias, hypertension, and associated comorbidities such as pulmonary diseases and metabolism dysfunction-associated steatotic liver disease and metabolism dysfunction-associated steatohepatitis (MASLD and MASH, respectively, formerly known as nonalcoholic fatty liver disease and nonalcoholic ...
Tópico(s): Pharmacology and Obesity Treatment
2024 - Elsevier BV | Metabolism
Nicolás Jackson, Andrea C. Ortiz, Alejandro Jerez, Javier Morales, Francisco Arriagada,
Stimuli-responsive nanomaterials have emerged as a promising strategy for inclusion in anticancer therapy. In particular, pH-responsive silica nanocarriers have been studied to provide controlled drug delivery in acidic tumor microenvironments. However, the intracellular microenvironment that the nanosystem must face has an impact on the anticancer effect; therefore, the design of the nanocarrier and the mechanisms that govern drug release play a crucial role in optimizing efficacy. Here, we synthesized ...
Tópico(s): Mesoporous Materials and Catalysis
2023 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
Rubén Tolosana, Rubén Vera-Rodríguez, Julián Fiérrez, Aythami Morales, Javier Ortega-García,
This paper describes the design, acquisition process and baseline evaluation of the new e-BioSign database, which includes dynamic signature and handwriting information. Data is acquired from 5 different COTS devices: three Wacom devices (STU-500, STU-530 and DTU-1031) specifically designed to capture dynamic signatures and handwriting, and two general purpose tablets (Samsung Galaxy Note 10.1 and Samsung ATIV 7). For the two Samsung tablets, data is collected using both pen stylus and also the finger ...
Tópico(s): Handwritten Text Recognition Techniques
2017 - Public Library of Science | PLoS ONE
Jose Morales, Johannes Flacke, Javier Morales, J.A. Zevenbergen,
Data scarcity is still a common barrier to adequately understanding urban access in Global South countries. Widely used location-based methods address the traditional definition of accessibility as the easiness to reach land-uses by means of available mobility modes. Space Syntax instead analyses accessibility as network centrality focusing only on the topological and geometric properties of urban layouts, making it comparatively less data-intense. However, the interpretation of its outputs is limited ...
Tópico(s): Urban Transport and Accessibility
2017 - Springer Science+Business Media | Applied Spatial Analysis and Policy
Alexandra R. Herrán, Jenifer Pérez-Andrés, Alberto Caminero, Esther Nistal, Santiago Vivas, José Morales, Javier Casqueiro,
Gluten is the only known environmental factor that triggers celiac disease. Several studies have described an imbalance between the intestinal microbiota of different individuals based on diagnoses. Moreover, recent studies have suggested that human bacteria may play an important role in gluten hydrolysis. However, there has been no research focusing on the small intestine. This study aimed to characterize the adult small intestine microbiota possibly implicated in gluten hydrolysis. Duodenal biopsies ...
Tópico(s): Microbial Metabolites in Food Biotechnology
2017 - Elsevier BV | Research in Microbiology
Abigail J. Morales, Javier A. Carrero, Putzer J. Hung, Anthony Tubbs, Jared Andrews, Brian T. Edelson, Boris Calderón, Cynthia L. Innes, Richard S. Paules, Jacqueline E. Payton, Barry P. Sleckman,
Macrophages produce genotoxic agents, such as reactive oxygen and nitrogen species, that kill invading pathogens. Here we show that these agents activate the DNA damage response (DDR) kinases ATM and DNA-PKcs through the generation of double stranded breaks (DSBs) in murine macrophage genomic DNA. In contrast to other cell types, initiation of this DDR depends on signaling from the type I interferon receptor. Once activated, ATM and DNA-PKcs regulate a genetic program with diverse immune functions ...
Tópico(s): Reproductive System and Pregnancy
2017 - eLife Sciences Publications Ltd | eLife
Guy Eyal, Matthijs B. Verhoog, Guilherme Testa-Silva, Yair Deitcher, Johannes C. Lodder, Ruth Benavides‐Piccione, Juan Morales, Javier DeFelipe, Christiaan P. J. de Kock, Huibert D. Mansvelder, Idan Segev,
The advanced cognitive capabilities of the human brain are often attributed to our recently evolved neocortex. However, it is not known whether the basic building blocks of the human neocortex, the pyramidal neurons, possess unique biophysical properties that might impact on cortical computations. Here we show that layer 2/3 pyramidal neurons from human temporal cortex (HL2/3 PCs) have a specific membrane capacitance ( C m ) of ~0.5 µF/cm 2 , half of the commonly accepted 'universal' value (~1 µF/cm 2 ) for ...
Tópico(s): Electrochemical Analysis and Applications
2016 - eLife Sciences Publications Ltd | eLife
Joan Albanell Mestres, A. B. iMolins, Lourdes Calvo, José Ignacio Chacón, Eva Ciruelos Gil, Ana de Juan Ferré, Sonia del Barco Berrón, Yolanda Fernández Pérez, Jesús García Mata, Andrés García Palomo, Joaquín Gavilá Gregori, P. Gómez Pardo, J J Illarramendi Mañas, Ana Lluch Hernández, Eduardo Martínez-De Dueñas, Noelia Martínez-Jáñez, Serafín Morales, Javier Salvador Bofill, Pilar Auñón, Pedro Sánchez‐Rovira,
Metastatic breast cancer is a heterogeneous disease that presents in varying forms, and a growing number of therapeutic options makes it difficult to determine the best choice in each particular situation. When selecting a systemic treatment, it is important to consider the medication administered in the previous stages, such as acquired resistance, type of progression, time to relapse, tumor aggressiveness, age, comorbidities, pre- and post-menopausal status, and patient preferences. Moreover, ...
Tópico(s): HER2/EGFR in Cancer Research
2016 - Springer Science+Business Media | Clinical & Translational Oncology
Asier García-Escárzaga, S. Moncayo, Igor Gutiérrez-Zugasti, Manuel R. González Morales, Javier Martı́n-Chivelet, Jorge O. Cáceres,
Mg/Ca ratios in shells of the mollusc species Phorcus lineatus obtained using the LIBS technique has been evaluated as an environmental proxy to reconstruct paleotemperatures and season of capture of molluscs for the first time.
Tópico(s): Isotope Analysis in Ecology
2015 - Royal Society of Chemistry | Journal of Analytical Atomic Spectrometry
María Guerra‐Álvarez, Ana J. Moreno‐Ortega, Elisa Navarro, José Carlos Fernández‐Morales, Javier Egea, Manuela G. López, María F. Cano‐Abad,
Positive allosteric modulation of α7 isoform of nicotinic acetylcholine receptors (α7-nAChRs) is emerging as a promising therapeutic approach for central nervous system disorders such as schizophrenia or Alzheimer's disease. However, its effect on Ca(2+) signaling and cell viability remains controversial. This study focuses on how the type II positive allosteric modulator (PAM II) PNU120596 affects intracellular Ca(2+) signaling and cell viability. We used human SH-SY5Y neuroblastoma cells overexpressing ...
Tópico(s): Neuroscience and Neuropharmacology Research
2015 - Wiley | Journal of Neurochemistry
Andrés Feher‐Voelger, Jorge Borges‐González, Romen Carrillo, Ezequiel Q. Morales, Javier González‐Platas, Tomás Martı́n,
Abstract New pyranoid ε‐sugar amino acids were designed as building blocks, in which the carboxylic acid and the amine groups were placed in positions C2 and C3 with respect to the tetrahydropyran oxygen atom. By using standard solution‐phase coupling procedures, cyclic homooligomers containing pyranoid ε‐sugar amino acids were synthesized. Conformation analysis was performed by using NMR spectroscopic experiments, FTIR spectroscopic studies, X‐ray analysis, and a theoretical conformation search. ...
Tópico(s): Glycosylation and Glycoproteins Research
2014 - Wiley | Chemistry - A European Journal
Obbina Abani, Amr E. Abbas, Fatima Abbas, Jonathan R. Abbas, Kaja Abbas, Mustafa Abbas, Sadia Abbasi, H Abbass, Anne L. Abbott, Nadine Abdallah, Ashraf Omar Abdelaziz, M Abdelfattah, Bushra Abdelqader, A Abdul, Basir Abdul, Sami Aftab Abdul, Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdullah Mohammed, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer Abeer Ul Amna, Laurent Abel, Kathy Abernethy, Movin Abeywickrema, Chandra Abhinaya, Ahmad Farid Abidin, Adebanke Aboaba, Abigail Aboagye-Odei, Christopher Aboah, Heba Aboelela, H Abo-Leyah, Karim Abouelela, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Ahmed Abousamra, M. Abouzaid, Mathew Abraham, Tizzy Abraham, A. Abraheem, J Abrams, Richard Abrams, HJ Abu, Ahmad Abu-Arafeh, SM Abubacker, Akata Abung, Yousef Abusamra, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Faustina Acheampong, Paul Acheampong, Sarah Acheampong, James Acheson, Shiella Achieng, Andrés Acosta, Rebecca Acquah, Cindy Acton, Jacqueline Adabie-Ankrah, Pauline Adair, AS Adam, Fiona Adam, Matthew Adam, Huzaifa Adamali, M Adamczyk, Christopher Adams, David H. Adams, Katie Adams, Lisa C. Adams, Nicholas M. Adams, Richard Adams, Tempestt Adams, Laura Adamu-Ikeme, Krishma Adatia, Kim G. Adcock, Lawrence Addai-Boampong, A. Addo, Oluwafemi Adeagbo, Adewole Adebiyi, O. S. Adedeji, Yewande Adegeye, K Adegoke, Vicki Adell, Sherna Adenwalla, FW Adeoye, OA Adesemoye, EO Adewunmi, A Adeyanju, Joyce Adeyemi, Titilope A. Adeyemo, Bidur Adhikari, SA Adhikari, R Adhikary, A. Aditya, Patience Adjepong, Gabrielle Adkins, Ahmad Adnan, M Adriaanse, J Aeron-Thomas, Debbie Affleck, Carmel Afnan, Muhammad Abdur Rahman Afridi, Patricia Afrim, FA Afriyie, ZA Aftab, Agnes Awuah, Mudit Agarwal, PN Agasiya, Rachel Agbeko, C Agbo, Sunil Aggarwal, A Aghababaie, L A Aguilar Jimenez, JA Agyekum, Kwame Agyen, EK Ahadome, S Ahamed Sadiq, MH Ahammed Nazeer, Ahmad Mukhtar, Saad Ahmad, Atheer Shehab Ahmed, BAR Ahmed, Bilal Ahmed, Farhan Ahmed, Helal Uddin Ahmed, Irshad Ahmed, Kawsar Ahmed, L Ahmed, Muhammad S. Ahmed, MC Ahmed, MS Ahmed, Nausheen Ahmed, Nausheen Ahmed, Osama Ahmed, Ahmed Ra, Rizwan Ahmed, Rizwan Ahmed, Sanam Ahmed, SG Ahmed, SH Ahmed, R Ahmed Ali, Bilal A Mohamud, Sanam Ahmed, Sana Ahmer, Augustine Ahonia, Clement Aidoo, C Aiken, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, L Aitken, B Ajay, Abdulakeem Ajibode, Ahdi Noomen Ajmi, Nahid Akhtar, Suha Akili, Bolutito Akinbiyi, O Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Muhammad Akram, Olugbenro Aktinade, Uzayr Akudi, ASAR Al Aaraj, Ali Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, A Alabi, Narendra Aladangady, Mahmoud Alafifi, AHM Khurshid Alam, Md. Samrat Alam, A Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, A. Albertus, Lorraine Albon, Antonio Luna, Gemma Alcorn, Stephen Alcorn, Andrés Gómez-Aldana, David Alderdice, Abdullah Aldesouki, Rayan Aldouri, Jonathan Aldridge, N. Aldridge, R. H. Good Ale, Ana Alegria, Amit Alexander, Craig J. Alexander, John H. Alexander, PDG Alexander, Julyan Al-Fori, Laith Alghazawi, Osama Alhabsha, Bahij Al-Hakim, R Alhameed, M Al-Hayali, Shams Al‐Hity, Ala Ali, FR Ali, Johar Ali, Mohammad Ali, MS Ali, Nayab Ali, Omar Hasan Ali, R Ali, Syed Ahsan Ali, Emilio Aliberti, J Alin, Abid Alina, Analyn Alipustain, Bachti Alisjahbana, Fine Aliyuda, Kaveh Alizadeh, Maithem Al-Jibury, Saja Al-Juboori, Mohammad Ali, Abdullah Alkhudhayri, Moutaz Alkhusheh, Frank N. Allan, Nicholas P. Allan, Alison Allanson, Robert Allcock, Emma Allen, Jason W. Allen, Keeley Allen, Louise Allen, Pamela B. Allen, R J Allen, Stephen Allen, Tammy D. Allen, Abiola Alli, Kelly C. Allison, Brent E. Allman, HK Allsop, Lynne Allsop, David Allsup, AFT Almahroos, Hassan Al-Moasseb, M Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Z Al-Saadi, Riyam Al-Sammarraie, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, F Alsheikh, Bashar Al‐Sheklly, S Altaf, A Alty, Míriam J. Álvarez, Maria Alvarez Corral, Edward Alveyn, Maysaa Alzetani, Susan Amamou, N Amar, S Ambalavanan, Robert Ambrogetti, Christopher S. Ambrose, A Ameen, Amel Amelia Ganefianty, Katharine Ames, M. R. Amezaga, A Amin, A Amin, Kawa Amin, S Amin, Tarek Tawfik Amin, B Amit, Awais Amjad, Nasser Mohammad Amjad, James Amoah-Dankwa, Amos Amoako-Adusei, Victoria Amosun, Mochammad Fariz Amsal, Khaled Amsha, John Amuasi, Noelia Martín, Pugh Amy, Ann Anada, Atul Anand, Samantha Anandappa, SD Anantapatnaikuni, NKN Andari, Élizabeth Anderson, Jennifer Anderson,
BackgroundEmpagliflozin has been proposed as a treatment for COVID-19 on the basis of its anti-inflammatory, metabolic, and haemodynamic effects. The RECOVERY trial aimed to assess its safety and efficacy in patients admitted to hospital with COVID-19.MethodsIn the randomised, controlled, open-label RECOVERY trial, several possible treatments are compared with usual care in patients hospitalised with COVID-19. In this analysis, we assess eligible and consenting adults who were randomly allocated ...
Elsevier BV
Marcel Risch, Dulce M. Morales, Javier Villalobos, Denis Antipin,
Implementation of chemical energy storage for a sustainable energy supply requires the rational improvement of electrocatalyst materials, for which their nature under reaction conditions needs to be revealed. For a better understanding of earth-abundant metal oxides as electrocatalysts for the oxygen evolution reaction (OER), the combination of electrochemical (EC) methods and X-ray absorption spectroscopy (XAS) is very insightful, yet still holds untapped potential. Herein, we concisely introduce ...
Tópico(s): Advanced battery technologies research
2022 - Wiley | Angewandte Chemie International Edition
J. González-Camejo, Ana Rita Morales, Javier Peña-Lamas, C. Lafita, S. Enguídanos, A. Seco, N. Martí,
Wastewater treatment plants (WWTPs) act as barriers in reducing uncontrolled microplastic and microlitter (MP-ML) emissions from both urban and industrial wastewaters. Despite removing most of the MP-ML, large quantities of this waste still enter the environment through WWTP effluents, which means further post-treatment technologies are needed. This study contains a technical evaluation of MP-ML removal from urban wastewater (UWW) and from the wastewater from the recycling plastic industry (PIWW) using ...
Tópico(s): Graphene and Nanomaterials Applications
2022 - Elsevier BV | Journal of Water Process Engineering
Rubén Tolosana, Rubén Vera-Rodríguez, Carlos González‐García, Julián Fiérrez, Aythami Morales, Javier Ortega-García, Juan Carlos Ruiz-García, Sergio Romero-Tapiador, Santiago Rengifo, Miguel Caruana, Jiajia Jiang, Songxuan Lai, Lianwen Jin, Yecheng Zhu, Javier Galbally, Moises Díaz, Miguel A. Ferrer, Marta Gomez‐Barrero, Ilya Hodashinsky, Konstantin Sarin, Артем Слезкин, Marina Bardamova, Mikhail Svetlakov, Mohammad Saleem, Cintia Lia Szcs, Bence Kővári, Falk Pulsmeyer, Mohamad Wehbi, Dario Zanca, Sumaiya Ahmad, Sarthak Mishra, Suraiya Jabin,
This article presents SVC-onGoing1, an on-going competition for on-line signature verification where researchers can easily benchmark their systems against the state of the art in an open common platform using large-scale public databases, such as DeepSignDB2 and SVC2021_EvalDB3, and standard experimental protocols. SVC-onGoing is based on the ICDAR 2021 Competition on On-Line Signature Verification (SVC 2021), which has been extended to allow participants anytime. The goal of SVC-onGoing is to evaluate ...
Tópico(s): Topic Modeling
2022 - Elsevier BV | Pattern Recognition
Joaquín Letelier, Silvia Naranjo, Ismael Sospedra, Juan Ramón Martínez‐Morales, Javier López-Rı́os, Neil H. Shubin, José Luis Gómez-Skármeta,
One of the central problems of vertebrate evolution is understanding the relationship among the distal portions of fins and limbs. Lacking comparable morphological markers of these regions in fish and tetrapods, these relationships have remained uncertain for the past century and a half. Here we show that Gli3 functions in controlling the proliferative expansion of distal progenitors are shared among dorsal and paired fins as well as tetrapod limbs. Mutant knockout gli3 fins in medaka (Oryzias latipes) ...
Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
2021 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Justin Stoler, Joshua D. Miller, Ellis Adjei Adams, Farooq Ahmed, Mallika Alexander, Gershim Asiki, Mobolanle Balogun, Michael J. Boivin, Alexandra Brewis, Genny Carrillo, Kelly Chapman, Stroma Cole, Shalean M. Collins, Jorge Escobar-Vargas, Hassan Eini‐Zinab, Matthew C. Freeman, Monet Ghorbani, Ashley Hagaman, Nicola L. Hawley, Zeina Jamaluddine, Wendy Jepson, Divya Krishnakumar, Kenneth Maes, Jyoti S. Mathad, Jonathan Maupin, Patrick Mbullo Owuor, Milton Marin Morales, Javier Morán‐Martínez, Nasrin Omidvar, Amber L. Pearson, Sabrina Rasheed, Asher Y. Rosinger, Luisa Samayoa-Figueroa, Ernesto C. Sánchez-Rodríguez, Marianne V. Santoso, Roseanne C. Schuster, Mahdieh Sheikhi, Sonali Srivastava, Chad Staddon, Andrea Sullivan, Yihenew Tesfaye, Alex Trowell, Desiré Tshala-Katumbay, Raymond Asare Tutu, Cassandra L. Workman, Amber Wutich, Sera L. Young,
Abstract Household survey data from 27 sites in 22 countries were collected in 2017–2018 in order to construct and validate a cross-cultural household-level water insecurity scale. The resultant Household Water Insecurity Experiences (HWISE) scale presents a useful tool for monitoring and evaluating water interventions as a complement to traditional metrics used by the development community. It can also help track progress toward achievement of Sustainable Development Goal 6 ‘clean water and sanitation ...
Tópico(s): Poverty, Education, and Child Welfare
2021 - IWA Publishing | Journal of Water Sanitation and Hygiene for Development
Emilia García Romero, Adrián Lorenzo, Andrea García-Vicente, Juan Morales, Javier García-Rivas, Mercedes Suárez,
The understanding of the structural formula of smectite minerals is basic to predicting their physicochemical properties, which depend on the location of the cation substitutions within their 2:1 layer. This implies knowing the correct distribution and structural positions of the cations, which allows assigning the source of the layer charge of the tetrahedral or octahedral sheet, determining the total number of octahedral cations and, consequently, knowing the type of smectite. However, sometimes ...
Tópico(s): Therapeutic Uses of Natural Elements
2021 - Wiley | Journal of Applied Crystallography