Satish K. Tadi, Carine Tellier-Lebègue, C. Nemoz, Pascal Drevet, Stéphane Audebert, Sunetra Roy, Katheryn Meek, Jean‐Baptiste Charbonnier, Mauro Modesti,
In mammalian cells, classical non-homologous end joining (c-NHEJ) is critical for DNA double-strand break repair induced by ionizing radiation and during V(D)J recombination in developing B and T lymphocytes. Recently, PAXX was identified as a c-NHEJ core component. We report here that PAXX-deficient cells exhibit a cellular phenotype uncharacteristic of a deficiency in c-NHEJ core components. PAXX-deficient cells display normal sensitivity to radiomimetic drugs, are proficient in transient V(D)J ...
Tópico(s): CRISPR and Genetic Engineering
2016 - Cell Press | Cell Reports
Patricia Auffret van der Kemp, Jean‐Baptiste Charbonnier, Marc Audebert, Serge Boiteux,
The human Ogg1 protein (hOgg1) is an antimutator DNA glycosylase/AP lyase that catalyzes the excision of 8‐oxo‐7,8‐dihydroguanine (8‐oxoG) and the incision of apurinic and apyrimidinic (AP) sites in DNA. In this study, we have investigated the functional role of H270, Q315 and F319, three amino acids that are located in the 8‐oxoG‐binding pocket of hOgg1. Wild‐type and mutant hOgg1 proteins (H270A, H270R, H270L, Q315A and F319A) were purified to apparent homogeneity. The catalytic activities and the ...
Tópico(s): Biochemical and Molecular Research
2004 - Oxford University Press | Nucleic Acids Research
Véronique Chevrier, Ange‐Line Bruel, Teunis J. P. van Dam, Brunella Franco, Melissa Lo Scalzo, Frédérique Lembo, Stéphane Audebert, Emilie Baudelet, Daniel Isnardon, Angélique Bôle, Jean‐Paul Borg, Paul Kuentz, Julien Thévenon, Lydie Bürglen, Laurence Faivre, Jean‐Baptiste Rivière, Martijn A. Huynen, Daniel Birnbaum, Olivier Rosnet, Christel Thauvin‐Robinet,
Oral-facial-digital (OFD) syndromes are rare heterogeneous disorders characterized by the association of abnormalities of the face, the oral cavity and the extremities, some due to mutations in proteins of the transition zone of the primary cilia or the closely associated distal end of centrioles. These two structures are essential for the formation of functional cilia, and for signaling events during development. We report here causal compound heterozygous mutations of KIAA0753/OFIP in a patient ...
Tópico(s): Hedgehog Signaling Pathway Studies
2015 - Oxford University Press | Human Molecular Genetics
... 19Barlage S. Gnewuch C. Liebisch G. Wolf Z. Audebert F.-X. Glück T. Fröhlich D. Krämer B. ... S. De Tymowski C. Assadi M. Zappella N. Jean-Baptiste S. Robert T. Peoc'h K. Lortat-Jacob ... S. De Tymowski C. Assadi M. Zappella N. Jean-Baptiste S. Robert T. Peoc'h K. Lortat-Jacob ...
Tópico(s): Vitamin C and Antioxidants Research
2021 - Elsevier BV | Journal of Lipid Research
Laurent Beaugerie, Fabrice Carrat, Stéphane Nahon, Jean–David Zeitoun, Jean‐Marc Sabaté, Laurent Peyrin‐Biroulet, Jean–Frédéric Colombel, Matthieu Allez, Jean–François Fléjou, Julien Kirchgesner, Magali Svrcek, Jean–Frédéric Colombel, Jacques Cosnes, Jean–Pierre Gendre, Marc Lémann, Xavier Hébuterne, Antoine Cortot, Yoram Bouhnik, David Laharie, Jean Louis Dupas, Bernard Flourié, Éric Lerebours, Laurent Beaugerie, Laurent Peyrin‐Biroulet, Matthieu Allez, Bernard Messing, Guillaume Cadiot, Philippe Marteau, Jean–Claude Soulé, Jean‐Marc Gornet, M Veyrac, Bernard Duclos, Philippe Beau, Arnaud Bourreille, P. Bäumer, Franck Carbonnel, D. Héresbach, Étienne-Henry Metman, C Florent, Antoine Blain, Jean‐Luc Faucheron, Bruno Bonaz, Xavier Roblin, Pascal Potier, Christian R. Boehm, Thierry Kurtz, H Lamouliatte, Isabelle Nion–Larmurier, Jean‐Charles Delchier, Stanislas Chaussade, Anne Marie Weiss, J.P. Cézard, Laurent Siproudhis, Stéphane Nahon, Daniel Sondag, Raymond Jian, Jean-Christophe Souquet, Pierre Bord, Benoît Coffin, H d’Almagne, Patrick Delasalle, Régis Fournier, Maryan Cavicchi, M. Souffran, Luc Vandromme, C Guédon, Philippe Seksik, Christophe Michiels, Pascal Renard, Patrice Rogier, S Gouilloud, André Rotenberg, Guillaume Savoye, A Thévenin, Laurent Mallet, Franck Brazier, F. Jean, Anne‐Marie Justum, Jean‐Paul Latrive, J. L. Gerbal, R Pierrugues, Gérard Chardonnal, Laurence Picon, N Reix, N d'Aubigny, Hervé Uettwiller, Anne Courillon Mallet, Alain Palacci, R. Bensaude, Pierre Bonniaud, Olivier Empinet, A Nisard, A. Rudelli, B Tubiana, P Capelle, A. Dabadie, D Evard, Pierre-Emile Julien, Magali Picon-Coste, S. Schneider, D Goldfain, J Bellanger, Jean-Pierre Blondelot, Philippe Lamy, Sébastien Lemière, Jean Francois Mockly, Benoit Pellat, Gilles Gatineau-Sailliant, Bernard Nalet, Stéphane Nancey, D Kusielewicz, P. Loison, Jean-Michel Popot, F Merite, Jean-Pol Roux, Pauline Afchain, A Blanquart, Laurent Heyries, Marc Reville, Dominique Viron, Frank Zerbib, Christophe Clavière, Didier Léostic, Philippe Pouderoux, Alain Moitry, Hervé Hagège, Jean‐Pierre Hugot, Benoît Humeau, Jean‐Marc Sabaté, Emmanuel Lederman, D. Lescut, Fabrice Luneau, B Mesnard, Lionel Smadja, Michel Steinberg, Marc Brun, Gilles Macaigne, Jean Luc Marchal, Stéphane Ollivier, D Ouvry, Jean Paul Perche, S Rambaud, Robert Benamouzig, Jean Louis Cazenave, Jean-Charles Coffin, Martine Blazquez, Marion Lagneau, Bruno Person, Christian Wittersheim, Bertrand Napoléon, I Cemachovic, F. Iglicki, Mehran Howaizi, Eric Leprince, Bruno Leurent, Thierry Morin, Riad Darsouni, Alain Attar, Philippe Baron, Anne Breton, J M Gillion, Jean-Marc Guemene, C Jouffre, Xavier Moreau, Pierre Claudé, André Quinton, Véred Abitbol, Jean Michel Brichard, B Desaint, Martin Bouygues, P Chatrenet, Marcelo Salmeron, J Silvie, Bruno Waldner, Yves Emery, Armand Moraillon, Daniel Kunkel, Philippe Dubois, Patrick Fauré, C L'Hirondel, Jean-Eric Labérenne, Pierre Moreau, Adelino Pereira, Genevieve Plihon, Thierry Wolff, Yann Ngô, Arnaud Boruchowicz, B Jost, Jean Pierre Gotlib, O Danne, Philippe Raoux, Marie-José Ramond-Bouhali, A Baetz, Bruno Veyres, C Chapoutot, Gérard Le Dréau, Jérôme Filippi, J Mudry, Philippe Kalt, S Minault, Pierre-André Bounin, Tony Andréani, J Charneau, Didier Reijasse, Jean-Louis Bolze, Jean Luc Thaunat, C Le Couteulx, C. Maurage, Robert Bader, Philippe Codjovi, Jean-Luc Migairou, A. Morali, Philippe Rey, B Richard Molard, Richard E. Petit, Stéphane Koch, Philippe Cassan, J Deschamps, Christine Meicler Caby, J.J. Meurisse, P Prades, James Boulant, Michel Diacono, J. M. MONSCH, J-François Dupuy, Guy Bellaïche, Martine Guegan, Jean-Marc Comte, Jean-Michel Cayla, Francois Le Tallec, F Meurisse, Philippe Desurmont, L Roget, Philippe Bouyssou, Bruno Le Gall, Francis Bloch, L Larvol, Monique Jullien, Jacques Moreau, Laurent Rebouissoux, Bruno Decroix, Nina Dib, Paul Dieterling, Frédéric Lenormand, E. Lagier, Philippe Fallourd, Serge Charpin, Hugues Bertrand, Gilles Bommelaer, Daniel Battistelli, Bernard Delon, L Dentant, Étienne Dorval, Jérôme Dumortier, Eric Gaye-Bareyt, Yves Gerosa, C Guez, M Mornet, Paul Benfredj, René Piperaud, Noël Stremsdoerfer, Eric Verdier, Alain Grinholtz, Georges Barjonet, A. T. A. See, Ramuntxo Arotçarena, A Baudet, Joël Broyer, Antoine Charachon, H. Blondon, Pascal Mouton, Hubert Claudez, Jacques Labat-Labourdette, J. Haem, P. Estable, Patrick Lévy, Alain Rosenbaum, Yvon Balavoine, A Blanchi, Pierre Coutarel, N. Delapérrière, M Dervichian, Francis Marois, Jacques Seroka, L. Michaud, O. Leroy, Emmanuel Meyran, Bernard Poilroux, Abdallah Tensaouti, Thierry Paupard, D Agard, Sandrine Beaulieu, K Benfiguig, P Capony, Jean Cottereau, Pierre Desreumaux,
Little is known about the magnitude of the risk of anal and rectal cancer in patients with anal and/or perineal Crohn's disease. We aimed to assess the risk of anal and rectal cancer in patients with Crohn's perianal disease followed up in the Cancers Et Surrisque Associé aux Maladies Inflammatoires Intestinales En France (CESAME) cohort.We collected data from 19,486 patients with inflammatory bowel disease (IBD) enrolled in the observational CESAME study in France, from May 2004 through June 2005; ...
Elsevier BV
Adelaide Buora, M Floriani, L. Gabrielli,
... PDF PubMed Scopus (37) Google Scholar, 11Töpel I. Audebert F. Betz T. Steinbauer M.G. Microbial spectrum ... PDF PubMed Scopus (42) Google Scholar, 16Batt M. Jean-Baptiste E. O'Connor S. Bouillanne P.J. Haudebourg ...
Tópico(s): Vascular Procedures and Complications
2013 - Elsevier BV | Journal of Vascular Surgery