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Artigo Revisado por pares

Guy Doré, Jean‐Marie Konrad, Marius Roy,

Pavements in cold climates are often subjected to transverse differential heaving. This phenomenon is the result of the more severe frost action under the unprotected road surface. It induces bending stresses in the pavement structure and ultimately causes longitudinal cracking at the pavement surface. A simple model to predict the initiation and the propagation rate of cracking induced by frost heave is proposed. The model is based on mechanistic principles and calibrated using field performance ...

Tópico(s): Soil, Finite Element Methods

1999 - SAGE Publishing | Transportation Research Record Journal of the Transportation Research Board

Artigo Revisado por pares

Guy Doré, Jean‐Marie Konrad, Marius Roy,

Frost action is a major cause of pavement deterioration in cold climates. Thermal cracking, differential heaving, and loss of bearing capacity during spring thaw are often identified as the main mechanisms involved. Except for thermal cracking, frost-susceptible subgrade soils are generally considered to be the source of the problems. Field observations suggest that frost action within the pavement granular layers could also contribute to pavement deterioration. Differential freezing conditions ...

Tópico(s): Cryospheric studies and observations

1997 - SAGE Publishing | Transportation Research Record Journal of the Transportation Research Board

Artigo Revisado por pares

Guy Doré, Jean Marie Konrad, Marius Roy, Nelson Rioux,

With freezing indexes ranging from 1,200 to over 2,000 deg C-days and frost penetration reaching 3 mm under pavement surface, frost action has always been a major concern for pavement engineers in Quebec, Canada. The province's ministry of transportation has thus undertaken a study on frost action in pavements with two main objectives. The first is to revisit the whole approach of pavement design in severe frost conditions and develop a rational pavement design method to mitigate efficiently the ...

Tópico(s): Concrete and Cement Materials Research

1995 - SAGE Publishing | Transportation Research Record Journal of the Transportation Research Board

Artigo Acesso aberto Revisado por pares

Oscar Acosta, Jürgen Fripp, Vincent Doré, Pierrick Bourgeat, Jean-Marie Favreau, Gaël Chételat, Andrea Rueda, Victor L. Villemagne, Cassandra Szoeke, David Ames, Kathryn A. Ellis, Ralph N. Martins, Colin L. Masters, Christopher C. Rowe, Erik Bonner, Florence Gris, Di Xiao, Parnesh Raniga, Vincent Barra, Olivier Salvado,

Magnetic resonance (MR) provides a non-invasive way to investigate changes in the brain resulting from aging or neurodegenerative disorders such as Alzheimer's disease (AD). Performing accurate analysis for population studies is challenging because of the interindividual anatomical variability. A large set of tools is found to perform studies of brain anatomy and population analysis (FreeSurfer, SPM, FSL). In this paper we present a newly developed surface-based processing pipeline (MILXCTE) that allows ...

Tópico(s): Functional Brain Connectivity Studies

2011 - Elsevier BV | Journal of Neuroscience Methods

Artigo Revisado por pares

Wei Lu, Rosângela Salerno-Gonçalves, Ju Yuan, Doré Sylvie, Dai Shu Han, Jean Marie Andrieu,

Objective During HIV-1 infection, CD4+ T lymphocytes migrate to immune-reactive lymphoid organs where they are infected by the virus and/or killed by apoptosis on immunoregulatory stimuli—a potential mechanism underlying fatal CD4+ T-cell depletion observed in AIDS. This study seeks to determine the effects of glucocorticoids (GCC) on the activation-induced T-cell apoptosis triggered by HIV-1. Methods CD4+ and CD8+ T cells were purified from HIV-negative donor peripheral blood mononuclear cells (PBMC) ...

Tópico(s): Immunotherapy and Immune Responses

1995 - Lippincott Williams & Wilkins | AIDS

Artigo

Sylvain Doré, Thierry Abribat, Nicole Rousseau, Paul Brazeau, Ginette Tardif, John A. DiBattista, Jean‐Marie Cloutier, Jean‐Pierre Pelletier, Johanne Martel‐Pelletier,

Abstract Objective . To investigate insulin‐like growth factor 1 (IGF‐1) production in normal and osteoarthritis (OA) chondrocytes and to further examine the role of growth hormone (GH) in adult human cartilage and, in particular, in diseased tissue. Methods . IGF‐1 production was measured with a radioimmunoassay. Binding assay, Northern blot, and reverse transcriptase polymerase chain reaction (RT‐PCR) techniques were used for GH receptor (GHR) detection. The biological response to GH was estimated via ...

Tópico(s): Cancer-related molecular mechanisms research

1995 - Wiley | Arthritis & Rheumatism

Artigo

Jean Pastré, Jean Marie Cantagrel,

La longue activité explosive du Mont Dore (3,8 à 0,3 Ma), la variété et la dissémination importante de ses téphras en font un stratovolcan d'intérêt majeur pour la corrélation téphrochronologique des formations plio-quaternaires du Massif Central français. Une étude de terrain détaillée et de nombreuses analyses minéralogiques et géochimiques permettent de proposer une nouvelle synthèse téphrostratigraphique calée par rapport aux datations radiométriques existantes (K-Ar et Ar-Ar). Il est ainsi montré ...

Tópico(s): Paleontology and Stratigraphy of Fossils

2001 - Association française pour l’étude du quaternaire | Quaternaire

Artigo Revisado por pares

Philippe Mossand, J. M. Cantagrel, Pierre Vincent,

... Haute-Dordogne; age et limites (Massif des Monts-Dore, France) Philippe Mossand; Philippe Mossand Author Cent. Natl. Res. Sci., Dep. Geol. et Mineral., Clermont-Ferrand, France Search for other works by this author on: GSW Google Scholar Jean-Marie Cantagrel; Jean-Marie Cantagrel Author Search for other ... Tools Get Permissions Search Site Citation Philippe Mossand, Jean-Marie Cantagrel, Pierre M. Vincent; La Caldera de Haute-Dordogne; age et limites (Massif des Monts-Dore, France). Bulletin de la Société Géologique de France ...

Tópico(s): Geology and Paleoclimatology Research

1982 - EDP Sciences | BSGF – Earth Sciences Bulletin

Artigo Acesso aberto Revisado por pares

Baher Mawlawi, Jean‐Baptiste Doré, N. I. Lebedev, Jean-Marie Gorce,

M2 M communication is information exchange between machines and machines without any human interaction. M2 M communication based on cellular network suffers from the extremely large number of devices in service coverage. In cellular network case, the large number of devices lead to communication problem caused by collisions between the senders. In this work we study the collision probability, saturation throughput and packet error rate for the carrier sense multiple access collision avoidance (CSMA/ ...

Tópico(s): Wireless Body Area Networks

2014 - Elsevier BV | Procedia Computer Science

Artigo Revisado por pares

Marina Guillet, Katia Gagne, David Lair, Jean‐Marie Heslan, Jean‐Christophe Doré, Jean‐Paul Soulillou, Sophie Brouard,

Abstract: Background: In the concordant hamster‐to‐rat cardiac xenograft model, recipients treated with cobra venom factor for the first 10 days following transplantation and daily with Cyclosporine A (CsA) do not reject their grafts. However, when CsA is withdrawn on day 40, an acute cellular rejection occurs within 4 ± 1 days. Allografts performed in the same conditions are rejected within 18 ± 4 days. Methods: In this model, we have compared graft infiltrating T cells through both a quantitative (number ...

Tópico(s): Renal Transplantation Outcomes and Treatments

2004 - Wiley | Xenotransplantation

Artigo Revisado por pares

X. Tillou, Jean Jacques Patard, Lionel Badet, Benoı̂t Barrou, Maxime Audet, H. Bensadoun, E. Berthoux, Pierre Bigot, Jean Michel Boutin, Ivan Bouzguenda, Damien Chambade, R. Codas, Jacques Dantal, J. Deturmeny, M. Devonec, A. Doerfler, B. Doré, F. Dugardin, Jean Ferrière, A. Erauso, B. Feuillu, B Gattegno, Marc Gigante, Laurent Guy, Georges Karam, Francois Kleinclaus, Thierry Lebrét, É. Lechevallier, Christophe Legendre, Christiane Mousson, Y. Neuzillet, Jean Philippe Rerolle, Thomas H. Perez, Laurent Salomon, Federico Sallusto, C. Sénéchal, Jacques Petit, N. Terrier, Rodolphe Thuret, G. Verhoest,

... Dantal, Julien Deturmeny, Marian Devonec, Arnaud Doerfler, Bertrand Dore, Fabrice Dugardin, Jean Marie Ferrière, Antoine Erauso, Benoit Feuillu, Bernard Gattegno, Marc ... Paris, France More articles by this author Bertrand Dore Poitiers, France More articles by this author Fabrice Dugardin Rouen, France More articles by this author Jean Marie Ferrière Bordeaux, France More articles by this author ...

Tópico(s): Renal Transplantation Outcomes and Treatments

2010 - Lippincott Williams & Wilkins | The Journal of Urology

Artigo Acesso aberto Revisado por pares

Baher Mawlawi, Jean‐Baptiste Doré, N. I. Lebedev, Jean-Marie Gorce,

Abstract In this work we study the collision probability, saturation throughput and statistical delay for the carrier sense multiple access collision avoidance (CSMA/CA) protocol with request to send and clear to send (RTS/CTS) mechanism in the case of frequency channel division. We propose in this paper a modified version of CSMA/CA-RTS/CTS to be compatible with the channel repartition technique and we prove that an important gain is introduced in terms of system performance especially for loaded ...

Tópico(s): IoT Networks and Protocols

2014 - Exeley Inc | International Journal on Smart Sensing and Intelligent Systems

Artigo

Brendan Fogarty,

... made somewhat of a novel move by appointing Jean-Marie Dore, a Guinean opposition leader as prime minister of ...

Tópico(s): African studies and sociopolitical issues

2010 - Harvard International Relations Council | Harvard international review

Artigo Acesso aberto Revisado por pares

Martin Lechenet, Violaine Deytieux, Daniele Antichi, Jean-Noël Aubertot, Paolo Bàrberi, Michel Bertrand, Vincent Cellier, Raphaël Charles, Caroline Colnenne‐David, Silke Dachbrodt‐Saaydeh, Philippe Debaeke, Thierry Doré, Pascal Farcy, César Fernández‐Quintanilla, Gilles Grandeau, Cathy Hawes, Lionel Jouy, Éric Justes, R. Kierzek, Per Kudsk, Jay Ram Lamichhane, Françoise Lescourret, Marco Mazzoncini, Bo Melander, Antoine Messéan, Anna‐Camilla Moonen, A. C. Newton, Jean Marie Nolot, Silvia Panozzo, Patrick Retaureau, Maurizio Sattin, Juergen Schwarz, Clotilde Toqué, Vasileios Vasileiadis, Nicolas Munier‐Jolain,

Integrated Pest Management (IPM) aims to promote physical and biological regulation strategies that help farmers contain populations of pests (pathogens, animal pests and weeds) and to finally reduce the reliance on pesticides. It is based on the holistic combination of multiple management measures rather than on the sum of single methods, each of them having only small effects on pests reduction. Thus, to analyse the interactions between IPM measures and to evaluate the sustainability of their implementation, ...

Tópico(s): Weed Control and Herbicide Applications

2016 - Elsevier BV | European Journal of Agronomy

Artigo Acesso aberto Revisado por pares

Fabienne Lesueur, Mahaut de Lichy, Michel Barrois, Guillermo Durand, Johny Bombled, Marie-Françoise Avril, Agnès Chompret, Françoise Boitier, G.M. Lenoir, M. Baccard, Bertrand Bachollet, Pascaline Berthet, Valérie Bonadona, Jean-Marie Bonnetblanc, J. Chevrant‐Breton, Jean-François Cuny, Stéphane Dalle, M. Delaunay, Liliane Demange, Julie De Quatrebarbes, J F Doré, Marc Frénay, Jean‐Pierre Fricker, Marion Gauthier-Villars, Paul Gesta, Sophie Giraud, Philippe Gorry, Florent Grange, Andrew R. Green, Laëtitia Huiart, Nicolas Janin, Pascal Joly, Delphine Kérob, Christine Lasset, Dominique Leroux, Jean–Marc Limacher, Michel Longy, Sandrine Mansard, Karine Marrou, Tanguy Martin‐Denavit, Christine Matéus, E. Maubec, Laurence Olivier-Faivre, V. Orlandini, Pascal Pujol, B. Sassolas, Dominique Stoppa-Lyonnet, L. Thomas, P. Vabres, Laurence Venat, Ewa Wierzbicka, Hélène Zattara, Brigitte Bressac–de Paillerets,

Mutations in two genes encoding cell cycle regulatory proteins have been shown to cause familial cutaneous malignant melanoma (CMM). About 20% of melanoma-prone families bear a point mutation in the CDKN2A locus at 9p21, which encodes two unrelated proteins, p16INK4a and p14ARF. Rare mutations in CDK4 have also been linked to the disease. Although the CDKN2A gene has been shown to be the major melanoma predisposing gene, there remains a significant proportion of melanoma kindreds linked to 9p21 in ...

Tópico(s): Immunotherapy and Immune Responses

2008 - Springer Nature | British Journal of Cancer

Artigo Acesso aberto Revisado por pares

Raymond Réau, Jean-Marie Bodet, Jean-Paul Bordes, Thierry Doré, Sabah Ennaïfar, Anne Moussart, Bernard Nicolardot, Sylvain Pellerin, Christian Plenchette, Alain Quinsac, Christophe Sausse, Bernard Séguin, Bernard Tivoli,

Brassicas contain glucosinolates (GSL) which decomposition is able to reduce the growth of populations of soil-borne fungi, bacterias or nematodes. These biocid effects on soil-borne microorganisms make a form of allelopathy phenomenon. The allelopathic properties depends on the GLS composition of the Brassicas: Indian mustard and in a lower extend Oilseed rape culd have the most powerfull action, White mustard would have a weaker action. These properties also depends on crop residues: green manure ...

Tópico(s): Plant Parasitism and Resistance

2005 - EDP Sciences | OCL

Artigo Acesso aberto Revisado por pares

Raymond Réau, Jean-Marie Bodet, Jean-Paul Bordes, Thierry Doré, Sabah Ennaïfar, Anne Moussart, Bernard Nicolardot, Sylvain Pellerin, Christian Plenchette, Alain Quinsac, Christophe Sausse, Bernard Séguin, Bernard Tivoli,

Brassicas contain glucosinolates (GSL) which decomposition is able to reduce the growth of populations of soil-borne fungi, bacterias or nematodes. These biocid effects on soil-borne microorganisms make a form of allelopathy phenomenon. The allelopathic properties depends on the GLS composition of the Brassicas: Indian mustard and in a lower extend Oilseed rape could have the most powerfull action, White mustard would have a weaker action. These properties also depends on crop residues: green manure ...

Tópico(s): Genomics, phytochemicals, and oxidative stress

2005 - EDP Sciences | OCL

Editorial Acesso aberto Revisado por pares

Dominic Pérennou, G. Amarenco, Philippe Azouvi, Jean-Marie Casillas, Emmanuel Coudeyre, Annette Doré, François Rannou, Gilles Rode,

Tópico(s): Health and Medical Studies

2014 - Elsevier BV | Annals of Physical and Rehabilitation Medicine

Artigo Acesso aberto Revisado por pares

Luc Bernard, Jean-Marie Doré, Paul Langlois,

Tópico(s): Philosophy, Sociology, Political Theory

1991 - University of Quebec in Montreal | Nouvelles pratiques sociales

Artigo Acesso aberto Revisado por pares

Aurore Goineau, L. Campion, Jean‐Marie Commer, Brigitte Vié, Agnès Ghesquière, G. Béra, Didier Jaffres, Nicolas Magné, Xavier Artignan, J. Chamois, Philippe Bergerot, G. Créhange, Élisabeth Deniaud-Alexandre, Xavier Buthaud, Yazid Belkacémi, Mélanie Dore, Laure de Decker, S. Supiot,

Curative radiotherapy for prostate cancer is common in the elderly. However, concerns about potential toxicity have inhibited access to radiotherapy for this population, for whom preserving quality of life (QoL) is crucial. The primary endpoint was to identify predictors of impaired QoL in men aged 75 years or older treated with curative intent radiotherapy with or without androgen deprivation therapy (ADT) for localized prostate cancer. We prospectively performed comprehensive geriatric assessment ( ...

Tópico(s): Cancer survivorship and care

2020 - Multidisciplinary Digital Publishing Institute | Cancers

Artigo Acesso aberto Revisado por pares

Stefano Aliberti, Luis Felipe Reyes, Paola Faverio, Giovanni Sotgiu, Simone Dore, Alejandro Rodríguez, Nilam J. Soni, Pedro J. Marcos, Patricia Aruj, Silvia Attorri, Enrique Barimboim, Juan Pablo Caeiro, María Isabel Garzón, Victor Hugo Cambursano, Adrián Ceccato, Julio Chertcoff, Florencia Lascar, Fernando Di Tulio, Ariel Cordon Díaz, Lautaro De Vedia, María Cristina Ganaha, Sandra Lambert, Gustavo Lopardo, Carlos M. Luna, Alessio Gerardo Malberti, Nora Morcillo, Silvina Tártara, Claudia Pensotti, Betiana Pereyra, Pablo Scapellato, Juan Pablo Stagnaro, Sonali Shah, Felix Lötsch, Florian Thalhammer, Jean‐Louis Vincent, Kurt Anseeuw, Camille A Francois, Eva Van Braeckel, Marcel Zannou Djimon, Jules Bashi, Roger Dodo, Simone Aranha Nouér, Peter Chipev, Milena Encheva, Darina Miteva, Diana Petkova, Adamou Dodo Balkissou, Eric Walter Pefura Yone, Bertrand Hugo Mbatchou Ngahane, Ning Shen, Jin‐Fu Xu, Carlos Andres Bustamante Rico, Ricardo Buitrago, Fernando Jose Pereira Paternina, Jean‐Marie Kayembe Ntumba, Vesna Vladic Carevic, Marko Jakopović, Mateja Janković, Zinka Matković, Ivan Mitrecic, Marie-Laure Bouchy Jacobsson, Anette Bro Christensen, Uffe Bødtger, C Meyer, Andreas Vestergaard Jensen, Gertrud Baunbæk-knudsen, Pelle Trier Petersen, Stine Linding Andersen, Ibrahim El-Said Abd El-Wahhab, Nesreen Elsayed Morsy, Hanaa Shafiek, Eman Sobh, Kedir Abdella Abdulsemed, Fabrice Bertrand, Christian Brun‐Buisson, Étienne de Montmollin, Muriel Fartoukh, Jonathan Messika, Pierre Tattevin, Abdo Khoury, Bernard E. Ebruke, Michael Dreher, Martin Kolditz, Matthias Meisinger, Mathias W. Pletz, Stefan Hagel, Jan Rupp, Tom Schaberg, Marc Spielmanns, Petra Creutz, Norton Suttorp, Beatrice Siaw-Lartey, Katerina Dimakou, Dimosthenis Papapetrou, Evdoxia Tsigou, Dimitrios Ampazis, Evangelos Kaimakamis, Mohit Bhatia, Raja Dhar, George D’Souza, Ravindra Kumar Garg, Parvaiz A Koul, P A Mahesh, B S Jayaraj, Kiran Vishnu Narayan, Hirennappa B Udnur, Shashi Bhaskara Krishnamurthy, Surya Kant, Rajesh Swarnakar, Sneha Limaye, Sundeep Salvi, Keihan Golshani, Vera M Keatings, Ignacio Martín‐Loeches, ‪Yasmin Maor‬‏, Jacob Strahilevitz, Salvatore Battaglia, Maria Carrabba, Piero Ceriana, Marco Confalonieri, Antonella d’Arminio Monforte, Bruno Del Prato, Marino De Rosa, Riccardo Fantini, Giuseppe Fiorentino, Maria Antonia Gammino, Francesco Menzella, Giuseppe Milani, Stefano Nava, Gerardo Palmiero, Roberta Petrino, Barbra Gabrielli, Paolo Rossi, Claudio Sorino, Gundi Steinhilber, Alessandro Zanforlin, Fabio Franzetti, Manuela Carugati, Manuela Morosi, Elisa Monge, Mauro Carone, Vincenzo Patella, Simone Scarlata, Andrea Comel, Kiyoyasu Kurahashi, Zeina Aoun Bacha, Daniel Barajas Ugalde, Omar Ceballos Zuñiga, José F Villegas, Milic Medenica, Ellen Garde, Deebya Raj Mihsra, Poojan Shrestha, Elliott Ridgeon, Babatunde Awokola, Ogonna Nwankwo, Adefuye Bolanle Olufunlola, Segaolu Olumide, Kingsley Nnanna Ukwaja, Muhammad Irfan, Łukasz Minarowski, Szymon Skoczyński, Felipe Froes, Pedro Leuschner, Mariana Meireles, Cláudia Ferrão, Pedro Leuschner, José Neves, Sofía Ravara, Victoria Brocovschii, Chesov Ion, Doina Rusu, Cristina Toma, Daniela Chirita, Carmen Dorobăț, Alexei Birkun, Anna Kaluzhenina, Abdullah Almotairi, Zakeya Abdulbaqi Ali Bukhary, Jameela Edathodu, Amal Fathy, Abdullah Mushira Abdulaziz Enani, Nazik Eltayeb Mohamed, Jawed Ulhadi Memon, Abdelhaleem Bella, Nada Bogdanović, Branislava Milenković, Dragica Pešut, Luis Borderías, Noel Manuel Bordon Garcia, Hugo Cabello Alarcón, Catia Cillóniz, Antoni Torres, Vicens Díaz-Brito, Xavier Casas, Alicia Encabo González, Maria Luisa Fernández-Almira, Miguel Gallego, Inmaculada Gaspar-GarcÍa, Juan González del Castillo, Patricia Javaloyes Victoria, Elena Laserna Martínez, Rosa Malo de Molina, Pedro J. Marcos, Rosario Menéndez, Ana Pando‐Sandoval, Cristina Prat, Alicia Lacoma de la Torre, Ignasi García-Olivé, Jordi Rello, Silvia Moyano, Francisco Sanz, Oriol Sibila, Ana Rodrigo‐Troyano, Jordi Solé‐Violán, Ane Uranga, Job F. M. van Boven, Ester Vendrell Torra, Jordi Almirall Pujol, Charles Feldman, Ho Kee Yum, Arnauld Attannon Fiogbe, F. Yangui, Semra Bilaçeroğlu, Levent Dalar, Ufuk Yılmaz, A. Ye. Bogomolov, Naheed Elahi, Devesh Dhasmana, Andrew Feneley, Rhiannon Ions, Julie Skeemer, Gerrit Woltmann, Carole Hancock, Adam T. Hill, Banu Rudran, Silvia Ruiz-Buitrago, Marion Campbell, Paul Whitaker, Alexander Youzguin, Anika Singanayagam, Karen Allen, Verónica Brito, Jessica Dietz, Claire E Dysart, Susan M. Kellie, Ricardo A Franco-Sadud, Garnet Meier, Mina Gaga, Thomas L Holland, Stephen P. Bergin, Fayez Kheir, Mark Landmeier, Manuel Lois, Girish B. Nair, Hemali Patel, Luis Felipe Reyes, William Rodriguez-Cintron, Shigeki Saito, Nilam J. Soni, Julio Noda, Cecilia I Hinojosa, Stephanie M. Levine, Luis F. Angel, Antonio Anzueto, K. Scott Whitlow, John Hipskind, Kunal Sukhija, Vicken Y. Totten, Richard G. Wunderink, Ray D Shah, Kondwelani Mateyo, Lorena Noriega, Ezequiel Alvarado, Mohamed Aman, Lucía Labra,

Antibiotic resistance is a major global health problem and pathogens such as meticillin-resistant Staphylococcus aureus (MRSA) have become of particular concern in the management of lower respiratory tract infections. However, few data are available on the worldwide prevalence and risk factors for MRSA pneumonia. We aimed to determine the point prevalence of MRSA pneumonia and identify specific MRSA risk factors in community-dwelling patients hospitalised with pneumonia.We did an international, multicentre ...

Elsevier BV | The Lancet Infectious Diseases

Artigo Acesso aberto Revisado por pares

Jean‐Michel Molina, Catherine Capitant, Bruno Spire, Gilles Pialoux, Laurent Cotte, Isabelle Charreau, Cécile Tremblay, Jean‐Marie Le Gall, Éric Cua, A. Pasquet, François Raffi, Claire Pintado, Christian Chidiac, Julie Chas, Pierre Charbonneau, Constance Delaugerre, Marie Suzan‐Monti, Bénédicte Loze, Julien Fonsart, Gilles Peytavin, Antoine Chéret, Julie Timsit, Gabriel Girard, Nicolas Lorente, Marie Préau, James F. Rooney, Mark A. Wainberg, David R. Thompson, Willy Rozenbaum, Véronique Doré, Lucie Marchand, Marie‐Christine Simon, Nicolas Etien, J Aboulker, Laurence Meyer, Jean-François Delfraissy,

Antiretroviral preexposure prophylaxis has been shown to reduce the risk of human immunodeficiency virus type 1 (HIV-1) infection in some studies, but conflicting results have been reported among studies, probably due to challenges of adherence to a daily regimen.We conducted a double-blind, randomized trial of antiretroviral therapy for preexposure HIV-1 prophylaxis among men who have unprotected anal sex with men. Participants were randomly assigned to take a combination of tenofovir disoproxil ...

Tópico(s): Sex work and related issues

2015 - Massachusetts Medical Society | New England Journal of Medicine

Artigo Acesso aberto Revisado por pares

Jean-Marie Prival, Andrew Harris, Elena Zanella, Claudio Robustelli Test, Lucia Gurioli, Oryaëlle Chevrel, Jonas Biren,

... free, phenocryst-rich, trachytic flow in the Monts Dore massif, France. Field work was carried out to ...

Tópico(s): Geological formations and processes

2022 - Geological Society of America | Geological Society of America Bulletin

Artigo Revisado por pares

Jörn Barfod, Katarzyna Cieślak, Patrik Reuterswärd, Lars Stackell, Erik Forssman,

... VI, 309 S., 143 Abb. und Grundrisse. Anne‐Dore Ketelsen‐Volkhardt. Schleswigholsteinische Epitaphien des 16. und 17. Jahrhunderts Studien zur schleswig‐holsteinischen Kunstgeschichte, Bd. 15, Neumünster 1989. John Michael Montias. Vermeerand His Milieu. A Web of Social History Princeton University Press 1989. ISBN 0–691–04051–6. Jean‐Marie Perouse De Montclos. Histoire de l'architecture française. ...

Tópico(s): Medieval European History and Architecture

1990 - Taylor & Francis | Konsthistorisk tidskrift/Journal of Art History

Artigo Acesso aberto Revisado por pares

Laurence Danober, G. Das Dores, Caroline Louis, Karine Llopis, Nathalie Dumas, Catherine Liard, Sylvie Girardon, Le Quement Catherine, Marie Bureau, Ali Krazem, Daniel Béracochéa, Thierry Pillot, Thierry Le Diguarher, Marc Bertrand, Alain Benoist, Jean‐Marie Fourquez, Anne‐Marie Chollet, Philippe Gloanec, Ross Jeggo,

Cognitive deficits are associated with several neurodegenerative and mood disorders. Among treatments, agonists and positive allosteric modulators of alpha7 nicotinic acetylcholine receptors (alpha7-nAChRs) have promising therapeutic potentials to enhance cognition. We have recently identified new compounds with a different mechanism of action compared to all previous known allosteric modulators and with a safe profile in vivo. The present study describes the cognitive-enhancing properties of S68890 ...

Tópico(s): Cholinesterase and Neurodegenerative Diseases

2019 - Wiley | Alzheimer s & Dementia

Artigo Revisado por pares

Jean-Marie Couderc,

... between three mountain groups of Massif Central : Monls-Dore in the North, Cézallier in the East and ...

Tópico(s): French Urban and Social Studies

1973 - Presses Universitaires de Rennes | Norois