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Artigo Acesso aberto Revisado por pares

Christian A. Schaer, Jeremy W. Deuel, Daniela Schildknecht, Leila Mahmoudi, Inés García‐Rubio, Catherine M. Owczarek, Stefan Schauer, Reinhard Kissner, Uddyalok Banerjee, Andre F. Palmer, Donat R. Spahn, David Irwin, Florence Vallelian, Paul W. Buehler, Dominik J. Schaer,

Rationale: Hemolysis occurs not only in conditions such as sickle cell disease and malaria but also during transfusion of stored blood, extracorporeal circulation, and sepsis. Cell-free Hb depletes nitric oxide (NO) in the vasculature, causing vasoconstriction and eventually cardiovascular complications. We hypothesize that Hb-binding proteins may preserve vascular NO signaling during hemolysis.Objectives: Characterization of an archetypical function by which Hb scavenger proteins could preserve ...

Tópico(s): Heme Oxygenase-1 and Carbon Monoxide

2015 - American Thoracic Society | American Journal of Respiratory and Critical Care Medicine

Artigo Revisado por pares

Jeremy Cribb, Lucas M. Plott, S. Snare, William J. Kissner, David B. Hill, R. Superfine,

Tópico(s): Proteoglycans and glycosaminoglycans research

2024 - Elsevier BV | Journal of Cystic Fibrosis

Artigo Acesso aberto Revisado por pares

... G. Santiso-Quinones, D. Stein, J. Bräuer, R. Kissner, F. Krumeich, H. Schönberg, J. Levalois-Grützmacher, H. ...

Tópico(s): Molecular Sensors and Ion Detection

2013 - Wiley | Angewandte Chemie International Edition

Artigo Acesso aberto Revisado por pares

... G. Santiso-Quinones, D. Stein, J. Bräuer, R. Kissner, F. Krumeich, H. Schönberg, J. Levalois-Grützmacher, H. ...

Tópico(s): Molecular Sensors and Ion Detection

2013 - Wiley | Angewandte Chemie