Jonathan Northcroft, Tracey Boles, John Dugdale, Hala Jaber, William Kay, John Sillers, Matthew Wall, Barbara Hall, Bill Gleave Chairman, Jim Munro, Jon Swain, Dominic Sandbrook, Günter Grass, Sally Brock, Helen Davies, Nicholas Rufford, Rob Hughes, Ian Wylie, Mariusz Lodkowski, Peter Whittle, F Parker, E Young, John Waples Business Editor, L Todd, Liz Hancock, Frank Whitford, Jenny Dalton, Ivo Tennant, Dr Raphael Ehan, Paul Hornby, Justine Roberts, David Smith, Mike Birarritz, Duncan Bannatyne, Neil Wormald, Peter Cosco, Mark Hughes, Andrew Sullivan, E P, Brian Saffer, Clive Davis, Trevor Allanson, K R, Adam Abdelnoor Cheif Executive, Nick Leslie, C D, Steve Barnes, Martin Jol, Paul Jewell, Tony Allen-Mills, Simon Wilde, William Hague, D C, Martin James, Ariel Leve, Andrew Franked, Robert Winnett, Andrew Clover, Sir Alex Ferguson, Irwin Stelzer, Peter Wilson, Rosie Millard, David Dougill, Arsene Wenger, D R, Peter Barron Editor, Christopher Hart, Colin Taylor, Wayne Rooney, Nick Savage, Geraldine Hackett, Paul Flynn, H C, Rob Maul, Alistair Weaver, Lynda Hopkins, Paul Forsyth, Hugh Canning, Isabel Oakeshott, Glenn Roeder, Jeremy Clarkson, David Cairns, John Topley, Edward Porter, Elizabeth Shepherd, Claire Newell, Michael Portillo, Julian Grenfell, Renny Snell, Giles Chapman, S L, Patricia Nicol, Sarah Dempster, Adrian Turpin, Brian Cox, Dave Pollard, Peter Logan, Kathy Shuttleworth, Anita Chaudhuri, Richard Fletcher, Sylvia Downing, Dominic Connell, Rafael Benitez, Jeremy Taylor, Jeff Potter, Sarah-Kate Templeton Health Correspondent, Paul Bailey, Jason Dack, Jenni Murray, Max Hastings, Michael Waugh, Paul Ham, Stuart Wavell, Christopher Silvester, Harry Redknapp, John Stobie, Angela Newing, Leo Sayer, Paul Kimmage, Giles Hattersley, Chris Woodhead, Monsieur Mangetout, Roy Richardson, Phill Spencer, Paul Driver, Derek Clements, Miami Vice, John Follain, Richard Brooks, Hyman Mintz, Arthur Lee, Ian Hawkey, Lord March, Stuart Andrews, Caroline Scott, David Leppard, Shelley Von Strunckel, Surinder Bassi, Mark Edwards, Heston Blumenthal, Trevor Hamley, Chris Coleman, Stephen Clarke, Ken Scants, Christina Lamb, Neil Warnock, Ross Lee, Raymond Keene, C L, Cliff Wilton, Rod Liddle, Lawrence Booth, Penelope Lively, Robbie Hudson, Ifor R Griffiths, Kipper Williams, David Moyes, Emma Smith, Stephen Jones, Dominic O'Connell, Stephen Bleach, Louise Armitstead, Uzi Mahnaimi, Mary Lobo, Nick Cain, Steve Coppell, Alan Pardew, Michael Wright, Jose Mourinho, James Dyson, Susan Kelly, Simon Burton, Caroline Donald, D Hall, Simon Baylik, Philip Sen, S A, Stuart Pearce, Rowan Williams, Trevor Lewis, Gareth Southgate, Caroline Branningan, David Gunn, S P, Colin McDowell, Stephen Armstrong, Adrian Boothroyd, John Elliott, Anna Mikhailova, Isabel Oakeshott Deputy Political Editor, Russell Miller, Bethan Cole, Antony Sattin, Lauren Howey, Roland White, N R, Steven Swinford, Alison Jane Reid, J Higgins, Abul Taher, J M Pinney, Rachel Johnson, Maurice Chittenden, Vincent Marcello, Mark Watts, Alastair McKay, Virginia Rounding, Mark Franchetti, Jon Ungoed-Thomas, Mike Brewer, Andrew Rogers, John Penman, M E, Sam Allardyce, Clare Francis, Michael Smith, John Harlow, Patrick Grant, Martin O'Neill, Fiona Bruce, Chris Haslam, Dipesh Gadher, Tom Baird, Mark Kleinman, Sarah Anderson, John Waples, Navid Akhtar, Mary Davies, Harry Arnold, A A Gill, David Parsons, Hunter Davies, Matthew Campbell, Brian Glanville, Daniel Foggo, Tom Steer, Martin Wroe, Dainel Emery, Soph Gill, W Pope, Margo Stilley, Simon Jenkins, Stephen Pettitt, Andrew Lycett, Claudia Croft, Jessica Bown, Olivia Cole, T L, Ciaran Hancock, R H, Sally Kinnes, Hollie Smith, Chris Morris, Roger Cooper, Clarence Barrett, Roger Dobson, Peter Almond, Kevin Baker Warrant Officer, Brian Doogan, John Aizlewood, Minette Marrin, Iain Dowie, J P, James Scoltock, Gordon Christian, Ken Lunn, Joe Lovejoy, Graham Norwood, Andrew Frankel, P W, David Budworth, Hugh Pearman, E U, Andrew Davidson, Dan Cairns, David Grylls, Katy Duke, Tony Balding, David Smith Economics Editor, Tom Deveson, R U, Sarah Baxter, Joanna Simon, Matthew Goodman, India Knight, Kate Spicer, Jason Dawe, Richard Lewis, Sian Griffiths, Helen Stewart,
... Dance Bolshoi Ballet Concerts London Winds Pop Juana Molina Saved by the belle The Bolshor's Cinderella ... the week ahead Great showman The Miracles Of Jesus (BBC1, 6.35pm) Survivor Alive (C4,8pm) Dogs' ...
2006 - Gale Group | Sunday Times HA GDA
William J. Tikunoff, Beatrice A. Ward,
... article:Enrique Rosales-Asensio, Carlos Sierra, Clara Pérez-Molina, Jesús Romero-Mayoral, Antonio Colmenar-Santos Teaching Using Collaborative ...
Tópico(s): Educational Innovations and Technology
1983 - University of Chicago Press | The Elementary School Journal
Jonathan Northcroft, Rupert Merson, John Dugdale, Hala Jaber, Nicolas Balfour, Dr Jane Goldman, Barbara Hall, Nigel Botherway, Fred Redwood, Jon Swain, Helen Davies, Peter Whittle, Sally Brock, Nicholas Rufford, Rob Hughes, Ross Noble, Jason Dawe, Dan Pearson, John Peter, Mark Hodgkinson, V S, Professor Gideon Garter, Jonathan Miller, Amanda Ursell, Andrew Longmore, Sharon Walker, Francesca Wickers, Liz Grant director, Mike Broad, J D, Emma Haughton, Amanda Hall, Gareth Walsh, Frank Whitford, Mark Thomson, Barry Elsom, Ferdinand Mount, Matt Wolf, Kathryn Cooper, William Lewis, P D, David Smith, David Mepham, Tim Richards, Paul Eavis Director, Peter Sharkey, David Cracknell Political Editor, Neil Wormald, Andrew Sullivan, Clive Davis, Sheherazade Goldsmith, Joe Lauria, Lynne Truss, Ellen MacArthur, Brad Butterworth, Professor Susan Sellers, Tony Allen-Mills, Simon Wilde, Martin James, Terence Blacker's, Irwin Stelzer, Peter Wilson, Rosie Millard, Mohammed al-Fassi, David Dougill, Rachel Dobson, Craig Rowland managing director, Jeremy Atiyah, Rob Maul, David Hewson, Grace Ciappara, David Bond, Eminem, Jonathon Carr-Brown, Roger Fletcher, Dermot Multins, Hugh Canning, Jeremy Clarkson, David Cairns, Edward Porter, Victoria Segal, Louise Taylor, Rodney Miskin, Mike Johnston international chairman, Nicola Smith, Helen Kenny, Patricia Nicol, Anthony Peregrine, Piercing, Paul Deputy ed, Eben Black, John O'Donnell, Lesley Fraser-Mitchell, Helen Monks, Ridley Scott, Liz Edwards, Bryn Jones, Travis Elborough, David Eimer, Adam Nathan, S W, Shelley von Strunckel, David Floyd, Paul Bailey, Dr Geoff Ogram, Brendan Bourne, Jane Tomlinson, Mike Laws, Raymond Blanc, Paul Ham, Christopher Silvester, Roger Eglin, Maggie Gee, Paul Donovan, John O'Shea, James Williams, Dominique Coughlin, Pat Cash, Paul Wray, Monsieur Mangetout, Chris Woodhead, Pat Manton, Steve Boyd, Lucinda Kemeny, Jasper Gerard, Mark Bishop chief executive, Martin Penner, Paul Driver, Bader ben Hirsi, Nicholas Hellen, Nick Newman, Richard Brooks, Gerald Hampton, Ian Hawkey, Felipe Fernandez-Armesto, Alex Clark, David Leppard, Amber Cowan, Paul Durman, Simone Baird, Mark Ludlow, Hugh Jamieson, Adam Jolly, Alicia Wyllie, Julia Corby, Mark Edwards, Michael Dibdin, Lisa Grainger, David Pope, Mick Dennis, Susan Clark, Hugh McLlvanney, Carl Ruck Professor, Eben Black Chief Political Correspondent, Lucy Wakefield, John Barry, James Lancaster, Dr Anthony Earnshaw, Christian Loehry, Karen Gold, Alan Combes, Sean Newsom, Raymond Keene, Gareth Huw Davies, Fiona Morrow, Douglas Alexander, Hugh Barton marketing director, David Cracknell, Harvey Elliot, Katrina Manson, Zoe Brennan, Cosmo Landesman, Diana Wright, Stephen Jones, Dominic O'Connell, Johnny Vegas, Richard Evans, Uzi Mahnaimi, Nick Cain, Barry Flatman, Louise Armitstead, Michael Wright, Melinda Stevens, Natalie Graham, Peter Boyle, Fiona Fullerton, M J, Caroline Donald, Kate Rew, Rob Ryan, Colin McDOWELL, Jill Robinson Founder & CEO, Bryn Evans, Michael Yardley, William Weston Chief Executive, Jack Grimston, Colin McDowell, Bryan Appleyard, Lois Rogers Medical Correspondent, David Lane, John Elliott, Ron Clarke, Jeremy Vine, Stephen Armstrong, Mark Anstead, Bethan Cole, R W Johnson, Jonathan Leake Environment Editor, David Price, Richard Woods, Roland White, Danny Roth, Ian Millington, Mark Palmer, Florence McMullan, Laurence Phillips, Mandy Garner, Shane Watson, Brian Guyett, Maurice Chittenden, Richard Brooks Arts Editor, Richard Rae, Mark Franchetti, Ray Hutton, George Harvey, Ian Bannerman, Lauren Quaintance, Marc Doyle, Tamara Cincik, John Harlow, Godfrey Smith, Denis Knowles, Robert Winnett Consumer Affairs Correspondent, Mervin Powell, Gary Steiger, Dipesh Gadher, Helen Mound, Barry Collins, James Foxall, John Waples, Hunter Davies, Juan Carlos Molina Rubio, A A Gill, David Parsons, Hilary Lowe, Matthew Campbell, Brian Glanville, Louise Johncox, Enda Leahy, Martin Haggett, Jacqui Goddard, Keith Butler-Wheelhouse chief executive, Sarah Curtis, Stephen Pettitt, Jason Mellor, Pam Barrent, Maria McErlane, John Spurling, Jason Corcoran, Sally Kinnes, David Wassell, Naomi Caine, Liam Clarke, David Wickers, S Hardman, Nigel Powell, Caroline Turriff, Brian Doogan, John Aizlewood, Minette Marrin, Frank Furedi, Aime Giral, Andrew Frankel, Hassan Yassin, Graham Norwood, James Knight, Rupert Steiner, David Budworth, Jo Holland, Steve Turner, Sarah Blake, Paul Stephen Lubicz, Julian Ryall, Bill Emmott, Hugh Pearman, Dan Cairns, Dea Birkett, Donal MacIntyre, Dorothy Wade, John Burns, David Smith Economics Editor, Jules Bueno, Isabel Unsworth, Sarah Baxter, Simon Wardell, Peter Roebuck, Matthew Goodman, India Knight, Victoria Stanley, Kingston Smith, Barry Newcombe, Dominic Rushe, Richard Lewis, Karen Robinson,
... strings 70s sex Radisson Edwardian Hotels Inside Was Jesus a user? Will America Surrender? America is the ... greatness Was there a whiff of cannabis about Jesus? Claims of drug use by biblical figures surprisingly ...
2003 - Gale Group | Sunday Times HA GDA
Michael A. Matthay, Anne F. Luetkemeyer,
... Estrada; Felix Gutierrez; Ferran Torres; Jose A Perez-Molina; Jesús Fortun; Luisa M Villar; Ulla Hohenthal; Harri Marttila; ...
Tópico(s): Long-Term Effects of COVID-19
2021 - American Medical Association | JAMA
Óscar Sánchez Ramón, Fernando Molina, Jesús Garćıa Molina, José Ambrosio Toval Álvarez,
Increasingly, the success of software systems depends largely on how their security requirements are satisfied. However, developers are challenged in implement- ing these requirements, mainly because of the gap between the specification and imple- mentation, and the technical complexities of the current software infrastructures. Re- cently, Model-Driven Security has emerged as a new software development area aimed at overcoming these difficulties. This new paradigm takes advantage of the benefits ...
Tópico(s): Service-Oriented Architecture and Web Services
2009 - Verlag der Technischen Universität Graz | JUCS - Journal of Universal Computer Science
Xavier Rosselló, Sergio Raposeiras‐Roubín, Roberto Latini, Alberto Domínguez‐Rodríguez, José A. Barrabés, Pedro L. Sánchez, Manuel Anguita, Felipe Fernández‐Vázquez, Domingo A. Pascual‐Figal, José M. de la Torre Hernández, Stefano Ferraro, A Vetrano, José-Ángel Pérez-Rivera, Óscar Prada‐Delgado, Noemí Escalera, Lidia Staszewsky, Gonzalo Pizarro, Jaume Agüero, Stuart J. Pocock, Filippo Ottani, Valentı́n Fuster, Borja Ibáñez, A. Gómez-Caro Andrés, Adriano Autieri, Albert Ariza, Alberto Cordero, Alessandra Costalunga, Alessandro Navazio, Alessandro Sionís, Alfonso Torres, Alfonso Serrano del Valle, Alfredo Bardajı́, Alfredo Renilla, Alina Olaru, Ana García‐Álvarez, A.M. Villanueva Campos, José-Ángel Pérez-Rivera, Annalisa Aloisi, Antoni Bayés‐Genís, Antonio Ignacio Fernández Ortiz, A Rizzo, Barbara Coutsoumbas, Beatrice Mariottoni, Camilla Zawaideh, Carlos González-Juanàtey, Carlos Tomás Querol, Carmen Rus, C Vimercati, Danilo Saverio Vetrano, Delicia Gentille, Eduardo Alegría, Eduardo Arroyo, Eduardo Moreno Escobar, Efrén Martínez‐Quintana, E Martinoli, Elvira Marco, Enrica Vitale, Enrico Nicolis, Erika Gazzola, Ezio Mesolella, Felipe Navarro, Francesco Manca, Francisco Fernández‐Avilés, Francisco Marín‐Ortuño, Francisco Torres, Gabriel Vázquez-Oliva, Gian Piero Perna, Gianni Casella, Giovanni Sirianni, Giuletta Grigis, Giulia Bugani, Giulia Pongetti, Giuseppe Di Tano, Gonzalo Navarrete, Héctor Bueno, Hugo Paris, I Moeller, I. Hernandez, Ivana Pariggiano, José Alberto San Román, Javier Botas, Jordi Palet, Jorge Sanz Sánchez, José A. Ramírez, José Ángel Cabrera, José Díaz, José Manuel García Ruiz, José Ramón González–Juanatey, José Rozado, Josep M. Alegret, Juan C. Garcı́a-Rubira, J L Bonilla, Juan Ruiz-García, Juan Sanchís, Julio Hernández, Lorenzo Calò, Ma Jesus Rollan, Manuel de Mora, Marco Solari, Maria Giulia Perrelli, Maria Rosa de Iacono, M Buffa, Mario Lombardi, Matteo Bianco, M Rondi, Natale Daniele Brunetti, Nicoletta De Cesare, Nicoletta De Santis, Óscar Díaz‐Cambronero, Óscar Fabregat‐Andrés, P Bazal, Pedro Morillas, Petra Sanz, P Basso, Ricardo Ieva, Roberto Carletti, Roberto Martín‐Asenjo, Román Freixa‐Pamias, Rosa L. Fernández, Rosario Ortas, Sabina Meloni, Stefano Tondi, Valentina Regazzoni, Vicente Mora, Agustín Martín García, A. Cervero, Alba Martín-Yebra, Albert Duran‐Cambra, Albert Massó-van Roessel, Alberto Pérez, A Pullara, Albina Aldomá, Alejandro Amador, Alejandro Junco-Vicente, Alejandro Pascual, Alejandro Domínguez-Rodríguez, Alejandro Sánchez Grande-Flecha, Alejandro Villanueva, Alice Vitagliano, Alicia Bautista Pavés, Alicia Gainza, Adna Sirley Ferreira Moreno, Álvaro Aceña, Alvaro Vicedo, Ana Elvira Laffond, Ana Isabel Santos, Ana María Moralejo, Ana Merino, Ana María Pello Lázaro, Ana Portolés, A Carbonell San Roman, A. Testa, Ana Ayesta, A. Cafro, Andrea Chiampan, A Finzi, Andrea Kallmeyer, Andrea López López, Andrea Rubboli, Andrea Veliz, Andrés Íñiguez, A. Gómez-Caro Andrés, Ane Aboitiz, Angel Franch, Angela Alonso, Angela Juez, Angélica Romero, Anna Carrasquer, Antonella Vasamì, Antoni Perelló-Bordoy, Antonia Sambola, Antonio Gámez, Antonio Jesus Martín, Antonio Lara‐Padrón, Antonio Miñano, Antonio Piñero, Antonio J. Quesada, Antonio Tello, Aritz Gil, Armando Pérez de Prado, Arturo Lanaspa, A Rubio Díaz, Beatriz de Tapia Majado, B. Saiz, Beatriz Samaniego, Beatriz Sampedro, Belén Cid Álvarez, Belén Prado, B Caneiro, Bernardo Ayala Borges, Berta Vega Hernández, Betel Olaizola, Blanca De-la-Cruz-Torres, Carla Jimenez, Carlos Baladrón, Carlos Galán, Carlos Miguito, Carlos Millan Rodriguez, Carlos Ortíz, Carmen Guerrero, Carmen Palacios, Carolina Hernández-Luis, Carolina Redondo, Carolina Sorto, Cecília Corros, Cecilia L. López, Charo Cortina, Chiara Angeletti, Claúdia C. dos Santos, Clea Gonzalez, Conchita Oliva, Cosme García‐García, Cristina González Cambeiro, Cristina Sánchez‐Enrique, C Tapia, Damaris de Sousa, Daniele Grosseto, Daniele Nassiacos, David Gomez, David Rutigliano, David Vivas, Deborah Cosmi, Diego Arroyo, Dolores Ruiz Fernández, Eduardo Barge Caballero, Eduardo Zatarain‐Nicolás, E. Barbaresi, Elena Batlle, Elena Rodríguez España, Elena Lopez, Elena Tundidor, E Saez De Buruaga, Elisabeth Fernández, Eliu David, Elizabet Méndez Eirín, Emad Abu Assi, Emanuela Clara Bertolino, Emilia Blanco‐Ponce, Enrico Cerrato, Enrico Gotti, Enrique Iglesias Río, Enrique Ponce de León, Enrique Sanchez, Ernesto del Amo, Ernesto Hernández, Esmeralda Capín, Ester Sánchez-Corral, E Vilei, Eva González, Eva Santamaría, Eva Santamaría, Fabrizio Poletti, Federica Del Giudice, Felice Achilli, Fernando Arribas, Filippo Maria di Dona, Flor Baeza, F Pietrucci, Francisco José Pastor, Francisco Burillo, Francisco Rivera, Fco Jesus Gonzalez, Gabriel Pajares Hurtado, G. Gallego Sánchez, Gabriella Foresti, Gaspar Melis, Gerard Oristrell, Gian Battista Danzi, Giancarlo Piovaccari, Gianfranco Pistis, Gil Bonet, Giovanni Tortorella, Gislaine Castilho de Oliverira, Gonzalo Serralta San Martín, Guillermo Moreno, H. García, Hernán Tajes, I. Aguilera García, Iciar Piedra, Idaira F. Hernandez-Baldomero, Ignacio Sánchez Pérez, I. Garcia Lunar, Inmaculada Piedra Fernández, Irene Buera, Irene Sempere, Irene García Toribio, I Romera Martinez, Iria Silva, Iris P. Garrido, Isabel Hernández, Itsaso Larrabide, I. Olavarri, Jairo Monedero, Jaume Pons, Javier Borrego, Javier Castrodeza,
Abstract Aims There is a lack of evidence regarding the benefits of β-blocker treatment after invasively managed acute myocardial infarction (MI) without reduced left ventricular ejection fraction (LVEF). Methods and results The tREatment with Beta-blockers after myOcardial infarction withOut reduced ejection fracTion (REBOOT) trial is a pragmatic, controlled, prospective, randomized, open-label blinded endpoint (PROBE design) clinical trial testing the benefits of β-blocker maintenance therapy in patients ...
Oxford University Press
E. Sarmiento, J. Fernàndez-Yáñez, Patricia Muñóz, Jesús Palomo, J. Rodrı́guez-Molina, Jesús F. Bermejo-Martín, Pilar Catalán, Emilio Bouza, Eduardo Fernández‐Cruz, Javier Carbone,
Secondary hypogammaglobulinemia after heart transplantation may follow immunosuppressive therapy with the resultant increased risk of infections, including cytomegalovirus (CMV) disease. There is limited information on the use of intravenous immunoglobulin replacement therapy (IVIG) in heart-transplanted patients with hypogammaglobulinemia and CMV disease. We present data on five consecutive heart-transplanted patients with relapsing CMV disease, four of whom developed gastrointestinal disease. The ...
Tópico(s): Parvovirus B19 Infection Studies
2004 - Elsevier BV | International Immunopharmacology
Zulema Udaondo, Estrella Duque, Matilde Fernández, Lázaro Molina, Jesús de la Torre, Patricia Bernal, José‐Luis Niqui, Cecilia Pini, Amalia Roca, Miguel A. Matilla, María Antonia Molina‐Henares, Hortencia Silva‐Jiménez, Gloria Navarro‐Avilés, Andreas Büsch, Jesús Lacal, Tino Krell, Ana Segura, Juan L. Ramos,
Pseudomonas putida strains are prevalent in a variety of pristine and polluted environments. The genome of the solvent-tolerant P. putida strain DOT-T1E which thrives in the presence of high concentrations of monoaromatic hydrocarbons, contains a circular 6.3 Mbp chromosome and a 133 kbp plasmid. Omics information has been used to identify the genes and proteins involved in solvent tolerance in this bacterium. This strain uses a multifactorial response that involves fine-tuning of lipid fluidity, ...
Tópico(s): Genomics and Phylogenetic Studies
2012 - Wiley | FEBS Letters
Silvia Cruz-Gil, Ruth Sánchez‐Martínez, Marta Gómez de Cedrón, Roberto Martín‐Hernández, Teodoro Vargas, Susana Molina, Jesús Herránz, Alberto Dávalos, Guillermo Reglero, Ana Ramı́rez de Molina,
An abnormal acyl-CoA synthetase/stearoyl-CoA desaturase (ACSL/SCD) lipid network fuels colon cancer progression, endowing cells with invasive and migratory properties. Therapies against this metabolic network may be useful to improve clinical outcomes. Because micro-RNAs (miRNAs/miRs) are important epigenetic regulators, we investigated novel miRNAs targeting this pro-tumorigenic axis; hence to be used as therapeutic or prognostic miRNAs. Thirty-one putative common miRNAs were predicted to simultaneously ...
Tópico(s): Cancer-related molecular mechanisms research
2017 - Elsevier BV | Journal of Lipid Research
Marta Gómez de Cedrón, Rebeca Acín‐Pérez, Ruth Sánchez‐Martínez, Susana Molina, Jesús Herránz, Jaime Feliú, Guillermo Reglero, José Antonio Enrı́quez, Ana Ramı́rez de Molina,
Cancer cell survival and metastasis are dependent on metabolic reprogramming that is capable of increasing resistance to oxidative and energetic stress. Targeting these two processes can be crucial for cancer progression. Herein, we describe the role of micro RNA ‐661 (miR661) as epigenetic regulator of colon cancer ( CC ) cell metabolism. MicroR661 induces a global increase in reactive oxygen species, specifically in mitochondrial superoxide anions, which appears to be mediated by decreased carbohydrate ...
Tópico(s): Cancer-related molecular mechanisms research
2017 - Elsevier BV | Molecular Oncology
Margarita González‐Vallinas, Teodoro Vargas, Juan Moreno‐Rubio, Susana Molina, Jesús Herránz, Paloma Cejas, Emilio Burgos, Cristina Aguayo, Ana Custodio, Guillermo Reglero, Jaime Feliú, Ana Ramı́rez de Molina,
Altered glycosylation is considered a universal cancer hallmark. Mucin-type core 2 1,6-N-acetylglucosaminyltransferase enzyme (C2GnT-M), encoded by the GCNT3 gene, has been reported to be altered in tumours and to possess tumour suppressor properties. In this work, we aimed to determine the possible role of GCNT3 gene expression as prognostic marker in colon cancer. We investigated the differential expression of GCNT3 gene among tumour samples from stage II colon cancer patients by quantitative reverse- ...
Tópico(s): Galectins and Cancer Biology
2014 - Elsevier BV | European Journal of Cancer
Jesús González de la Aleja, Ana Regina Lima Ramos, Virginia Mato‐Abad, Antonio Martínez‐Salio, Juan A. Hernández‐Tamames, José Antonio Molina, Jesús Hernández‐Gallego, Juan Álvarez‐Linera,
Background Glutamate ( G lu) and glutamine ( G ln) are strongly compartmentalized (in neurons for G lu and in astrocytes for G ln). The visual cortex is the brain region with a higher neuron/astrocyte ratio (the highest neuronal density and the relatively lowest density of astrocytes). Elevations in extracellular G lu or potassium above certain thresholds are likely candidates to be the final common steps in the multiple distinct processes that can lead to cortical spreading depression. Astrocytes play ...
Tópico(s): Transcranial Magnetic Stimulation Studies
2012 - Wiley | Headache The Journal of Head and Face Pain
Esther Ramos Boluda, F Hernández, Ane Miren Andrés, Eva Martínez‐Ojinaga, Manuel Molina, Jesús Sarría, Manuel López‐Santamaría, Gerardo Prieto,
PTLDs are a well-recognized and potentially fatal complication after intestinal transplantation. We analyzed the incidence, clinical features, and outcome in a 63 intestinal transplantation series performed in our unit between October 1999 and July 2011. Types of graft included ISB (n = 23), LSB (n = 20), and MV (n = 20). Patients were categorized into three groups of immunosuppression: I (n = 43) received basiliximab, tacrolimus, and steroids; II (n = 11) thymoglobulin and tacrolimus, and III (n = 9) alemtuzumab ...
Tópico(s): Cytomegalovirus and herpesvirus research
2013 - Wiley | Pediatric Transplantation
T Bricio, A. Molina, Jesús Egido, Eva González, F Mampaso,
SUMMARY Rats receiving a single dose of adriamycin (7·5 mg/kg) develop heavy proteinuria and morphological abnormalities similar to those observed in minimal change nephrotic syndrome in humans. IL-1-concomitance between enhanced I-a display by resident glomerular macrophages. IL-1-like cytokine secreted by whole isolated rat glomeruli and proteinuria was observed in adriamycin-injected rats during the experimental protocol. In addition, in vitro studies have shown that after stimulation with adriamycin ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
1992 - Oxford University Press | Clinical & Experimental Immunology
José Manuel Molina, Jesús Garcı́a, F.J. Jimenez Rodriguez, José Ramón Casar Corredera,
The use of distributed artificial intelligence (DAI) techniques, particularly the multiagent systems theory, in a decentralized architecture, is proposed to manage cooperatively, all sensor tasks in a network of (air) surveillance radars with capabilities for autonomous operation. At the multisensor data fusion (DF) center, the fusion agent will periodically deliver to sensor agents a list with the system-level tasks that need to be fulfilled. For each system task, indications about its system-level ...
Tópico(s): AI-based Problem Solving and Planning
2003 - Wiley | International Journal of Intelligent Systems
Fernando Molina, Jesús Pardillo, Ambrosio Toval,
In recent years, Web Information Systems (WIS) development projects have grown increasingly complex and critical for the smooth running of the organizations. However, recent studies reveal that a high percentage of web-based development projects miss the quality parameters required by stakeholders, most of the time due to an incorrect requirements management. In this paper, we try to increase the weight of requirements engineering activities in Web Engineering, and propose a web engineering requirements ...
Tópico(s): Model-Driven Software Engineering Techniques
2008 - Springer Science+Business Media | Lecture notes in computer science
Ane Miren Andrés, Manuel Santamarı́a, Esther Ramos Boluda, F Hernández, Gerardo Prieto, José Luis Encinas, Núria Leal, Manuel Molina, Jesús Sarría, Juan A. Tovar,
To review our experience with SRL as a second-line therapy in our series of 45 SBTx recipients (1997-2009). Retrospective review of five children converted to SRL: 3 M/2 F; median of three yr old (range 20 months-18 yr); rescue indications, adverse events with SRL, resolution of tacrolimus-related side effects, incidence of rejection, PTLD, or GVHD were summarized. Tacrolimus was discontinued (average 13 months after transplant) because of refractory hemolytic anemia in four patients with decreased ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2010 - Wiley | Pediatric Transplantation
Ignacio Párraga Martínez, Beatriz Navarro Bravo, Fernando Andrés‐Pretel, Juan Noé Denia Muñoz, Rocío Pilar Elicegui Molina, Jesús López‐Torres Hidalgo,
To determine the association between fear of falling and health status, a history of previous falls and personal characteristics in a representative sample of elderly people.We conducted an observational, cross-sectional prevalence study in the community setting in Albacete (Spain) of 921 people older than 65 years old selected through simple randomization. Participants underwent semi-structured interviews about their history of falls, fear of falling, illnesses and sociodemographic characteristics. ...
Tópico(s): Chronic Disease Management Strategies
2010 - Elsevier BV | Gaceta Sanitaria
Gonzalo Botija Arcos, Marta Ybarra, Esther Ramos Boluda, Manuel Molina, Jesús Sarría, Eva Martínez‐Ojinaga, Ane Miren Andrés, Manuel López‐Santamaría, Gerardo Prieto,
Tópico(s): Immunodeficiency and Autoimmune Disorders
2010 - Springer Science+Business Media | Transplant International
Ana I. Molina, Jesús Gallardo, Miguel Á. Redondo, Manuel Ortega, William J. Giraldo,
This work is framed in the area of software development for Computer Supported Cooperative Work (CSCW). These software systems are called groupware systems. The development of groupware systems is a complex task, a problem that can be addressed applying the Model Driven Engineering (MDE) principles and techniques, where the use of models is essential. However, there are no proposals to address all issues to model in this kind of application (group work, shared context, coordination, etc.) and, in particular, ...
Tópico(s): Model-Driven Software Engineering Techniques
2012 - Elsevier BV | Journal of Systems and Software
Margarita de Lorena Ramos‐García, Elsa Bosquez‐Molina, Jesús Hernández‐Romano, Guadalupe Zavala-Padilla, Eduardo Térres‐Rojas, Irán Alía-Tejacal, Laura Leticia Barrera‐Necha, Mónica Hernández‐López, Silvia Bautista‐Baños,
During storage of tomatoes, Rhizopus stolonifer rapidly spreads towards adjacent fruits causing severe economic losses while Escherichia coli may cause serious even life threatening diseases. Chitosan-based materials can be used as edible films or coatings to avoid water loss and microbial spoilage. Waxes and essential oils may also be considered for use as antimicrobial agents in chitosan coating. In this study, various chitosan-based formulations (1%) mixed with beeswax (0.1%), oleic acid (1.0%), ...
Tópico(s): Insect Pest Control Strategies
2012 - Elsevier BV | Crop Protection
Sergio M. Vicente‐Serrano, Santiago Beguerı́a, Jorge Lorenzo‐Lacruz, J. Julio Camarero, Juan Ignacio López‐Moreno, César Azorín-Molina, Jesús Revuelto, Enrique Morán‐Tejeda, Arturo Sanchez‐Lorenzo,
Abstract In this study, the authors provide a global assessment of the performance of different drought indices for monitoring drought impacts on several hydrological, agricultural, and ecological response variables. For this purpose, they compare the performance of several drought indices [the standardized precipitation index (SPI); four versions of the Palmer drought severity index (PDSI); and the standardized precipitation evapotranspiration index (SPEI)] to predict changes in streamflow, soil moisture, ...
Tópico(s): Hydrology and Watershed Management Studies
2012 - American Meteorological Society | Earth Interactions
José A. Pérez‐Molina, Jesús Sojo-Dorado, Francesca Norman, Begoña Monge‐Maíllo, Marta Díaz‐Menéndez, Pedro Albajar-Viñas, Rogelio López‐Vélez,
Currently, only two drugs are approved for treating Trypanosoma cruzi infection: benznidazole and nifurtimox. Adverse reactions are frequent with both drugs: they have chemical similarities and common metabolic pathways making cross reactions a possibility. Our objective was to describe the safety/tolerability profile of nifurtimox in patients who had previously discontinued benznidazole due to hypersensitivity reactions. We performed a prospective observational study from September 2009 to December ...
Tópico(s): Synthesis and Biological Evaluation
2013 - Elsevier BV | Acta Tropica
Yamilé Molina, Jesús Ramírez-Valles,
Despite the increased interest in HIV/AIDS stigma and its negative effects on the health and social support of people living with HIV/AIDS (PLWHA), little attention has been given to its assessment among Latino gay/ bisexual men and transgender women (GBT) living with HIV/AIDS. The purpose of this paper is twofold: to develop a multidimensional assessment of HIV/AIDS stigma for Latino GBT living with HIV/AIDS, and to test whether such stigma is related to self-esteem, safe sex self-efficacy, social ...
Tópico(s): LGBTQ Health, Identity, and Policy
2013 - Taylor & Francis | AIDS Care
Johannes Stolz, Horacio Molina, Jesús Alejandro Guzmán Ramírez, Nikolaus Mohr,
Abstract The purpose of our research is to find out about the consumer's perception of environmental retailing performance. Furthermore, consumer motives leading to sustainable consumption are measured by how they influence the consumer perception. Our study is divided into two parts and based on an international survey ( n = 989) comparing G erman and S panish consumers. First, we measure the perceiving availability and visibility of sustainable products in retail stores. Second, the impact of personal ...
Tópico(s): Consumer Behavior in Brand Consumption and Identification
2013 - Wiley | International Journal of Consumer Studies
A. Romeu, Inmaculada Molina, Jesús A.F. Tresguerres, M. Pla, José A. Peinado,
A total of 40 New Zealand female rabbits which had been given follicular stimulation and artificial insemination received 50 IU of either recombinant human luteinizing hormone (rhLH; n = 20) or human chorionic gonadotrophin (HCG; n = 20) to induce ovulation. In each hormone group, 10 animals were killed 72 h later to study the ovulatory process and the number, location, morphological quality and variation in the degree of development of recovered embryos. Pre-ovulatory and post-ovulatory oestradiol and ...
Tópico(s): Reproductive Biology and Fertility
1995 - Oxford University Press | Molecular Human Reproduction
Carlos López Casado, C. Sanz de Galdeano, Sergio Molina, Jesús Henares,
Almost all the earthquakes included in the catalog for the Iberian–Maghrebian area up to 2000 have been used in order to know the structure of the Alboran Sea area after the verification of the aleatory nature of the errors in their spatial localization. A new focal mechanisms catalog has also been used as well as many of the available geological data. During the Mesozoic and till the Oligocene, the Betic–Rif Internal Zone was situated further E, but with the opening of the Algero-Provençal basin ...
Tópico(s): Geological and Geochemical Analysis
2001 - Elsevier BV | Tectonophysics
Naiara Moreira, Elías Molina, Jesús Lázaro, Eduardo Jacob, Armando Astarloa,
The cyber-security of several industrial plants has been compromised for last years by some worms and viruses, such as Stuxnet, which was able to take control of the Supervisory Control And Data Acquisition (SCADA) system of a nuclear plant in Iran. The research community and the international standardization committees raised their awareness about protecting information in Substation Automation Systems (SAS). IEC 61850-5 and IEC 62351-6 standards respectively describe communication models and the ...
Tópico(s): Cryptographic Implementations and Security
2015 - Elsevier BV | Renewable and Sustainable Energy Reviews
Carles Soler, Almudena García‐Molina, Jesús Contell, Miguel Á. Silvestre, M. Sancho,
Evaluation of sperm morphology is a fundamental component of semen analysis, but its real significance has been obscured by a plethora of techniques that involve fixation and staining procedures that induce artefacts. Here we describe Trumorph℗®, a new method for sperm morphology assessment that is based upon examination of wet preparations of living spermatozoa immobilized by a short 60°C shock using negative phase contrast microscopy. We have observed samples from five animals of the following ...
Tópico(s): Reproductive biology and impacts on aquatic species
2015 - Elsevier BV | Animal Reproduction Science
Juan Ignacio López‐Moreno, Enrique Morán‐Tejeda, Sergio M. Vicente‐Serrano, Juan Bazo, César Azorín-Molina, Jesús Revuelto, Arturo Sanchez‐Lorenzo, F. Navarro‐Serrano, Enric Aguilar, O. Chura,
This work analysed the changes in air temperature in 25 meteorological stations in the Altiplano and the surrounding Andean slopes of Bolivia and Peru, and their relationship with El Niño-Southern Oscillation (SO) and the Pacific Decadal Oscillation (PDO). The analysis focused on annual, warm season (DJF) and cold season (JJA) maximum and minimum temperatures. All analyses were undertaken during 1965–2012, but some analyses were also from 1945 and 1955 when data were available. Principal component analysis ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2015 - Wiley | International Journal of Climatology