Damián García‐Olmo, Jesús Ontañón, Dolores C. Garcı́a-Olmo, Mario Vallejo, Jesús Cifuentes,
The benefits of the "no-touch" isolation technique usually performed to prevent the circulation of tumor cells are not evident. The aim of this study was to determine whether conventional surgical procedures for treatment of colon cancer could provoke the circulation of tumor cells detected by a genetic technology.Sixteen patients undergoing resection for colorectal cancer and two patients with irresectable tumors were studied. No patient showed liver or lung metastasis. With specific primers for ...
Tópico(s): 3D Printing in Biomedical Research
1999 - Lippincott Williams & Wilkins | Diseases of the Colon & Rectum
Enrique Olmos, Jesús García De La Garma, M.C. Gómez-Jiménez, Nieves Fernández‐García,
Arabinogalactan proteins (AGPs) are a highly diverse family of glycoproteins that are commonly found in most plant species. However, little is known about the physiological and molecular mechanisms of their function. AGPs are involved in different biological processes such as cell differentiation, cell expansion, tissue development and somatic embryogenesis. AGPs are also involved in abiotic stress response such as salinity modulating cell wall expansion. In this study, we describe how salt-adaptation ...
Tópico(s): Plant Reproductive Biology
2017 - Frontiers Media | Frontiers in Plant Science
Marı́a T. Zarrabeitia, José A. Riancho, J.A. Amado, José M. Olmos, Jesús González‐Macías,
Cells of the monocyte/macrophage lineage express specific receptors for calcitriol (1,25-dihydroxyvitamin D3) and secrete prostaglandins and several cytokines with potent effects on bone metabolism. The aim of this study was to determine the effect of calcitriol on the secretion of prostaglandin E2 (PGE2), interleukin-1 (IL-1), and tumor necrosis factor (TNFα). Monocyte-enriched peripheral blood mononuclear cells (PBMC) from healthy subjects were cultured in the presence or absence of calcitriol (10−11 − ...
Tópico(s): Advanced Glycation End Products research
1992 - Elsevier BV | Bone
Almudena Martínez del Olmo, Jesús Leal Maldonado,
A través del contexto madrileño el siguiente artículo analiza la problemática residencial de los inmigrantes económicos en base a los procesos de exclusión residencial y segregación espacial con el fin de demostrar hasta que punto ambos llegan a coincidir. Para ello se aplican indicadores residenciales claves e índices de segregación, obtenidos a partir de fuentes de análisis secundarias (Encuesta de Estructuras Salariales, Censo de Población y Viviendas, Padrón de Habitantes) y cuyos resultados ...
Tópico(s): Migration, Aging, and Tourism Studies
2008 - Universitat Politècnica de Catalunya | ACE Arquitectura Ciudad y Entorno
José L. Hernández, José M. Olmos, Jesús González‐Macías,
Abstract The metabolic syndrome (MetS) is a cluster of cardiovascular risk factors which has been suggested to have a possible effect on bone mass. Somewhat paradoxically, it is not clear whether this effect is protective or detrimental. Some of its components (e.g., obesity) seem to have the first type of effect and others (e.g., glucose metabolism changes) the second one. The epidemiological studies are not conclusive. Five out of six cross-sectional studies show no differences in the rate of fractures between ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2011 - Elsevier BV | Maturitas
Luisa Ugedo, M. Asier Garro, Joseba Pineda, M. Teresa Giralt, Antonio Miralles, Gabriel Olmos, Jesús A. García-Sevilla, Àngel Menargues, Rossend Obach,
The specific binding of the agonist, [3H]UK 14304, and of the antagonist, [3H]RX 821002, to rat brain membranes, as well as clonidine-induced mydriasis, clonidine-induced inhibition and idazoxan-induced stimulation of brain 3,4-dihydroxyphenylalanine (DOPA) synthesis, and clonidine and UK 14304-induced inhibition of twitch responses in the vas deferens were used to evaluate the affinity and sensitivity of central and peripheral α2-adrenoceptors after various treatments with reserpine. Treatment with ...
Tópico(s): Neuropeptides and Animal Physiology
1993 - Elsevier BV | European Journal of Pharmacology
Antonio Miralles, Catalina Ribas, Gabriel Olmos, Jesús A. García‐Sevilla,
The alkylating agent N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) is a peptide-coupling agent that is being used to inactivate irreversibly alpha 2-adrenoceptors and other receptors. The aim of the present study was to assess the in vitro and in vivo effects of EEDQ on the newly discovered brain I2-imidazoline sites, located mainly in mitochondria. Preincubation of rat cortical membranes with EEDQ (10(-8)-10(-5) M) markedly decreased (20-90%) the specific binding of the selective antagonist [ ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
1993 - Wiley | Journal of Neurochemistry
J Napal, J.A. Amado, José A. Riancho, José M. Olmos, Jesús González‐Macías,
During a study undertaken to characterize the time course of the osteocalcin response to bone fractures, lower than normal values of serum osteocalcin (1.7 +/- 0.9 vs. 3.3 +/- 1.3 ng/ml, P < 0.001) were found in the basal samples (blood obtained 48-72 h after fracturing). Suspecting that such a decrease could be due to the stress response induced by the fracture, for corticosteroids are known to diminish serum osteocalcin, we extended our study to another two stressful situations of high stress: acute myocardial ...
Tópico(s): Vitamin C and Antioxidants Research
1993 - Elsevier BV | Bone and Mineral
Manuel Olías Álvarez, J. C. Cerón, Ignacio Fernández-Olmo, Jesús de la Rosa,
This work analyses the spatial distribution, the origin, and the shale-normalised fractionation patterns of the rare earth elements (REE) in the alluvial aquifer of the Guadiamar River (south-western Spain). This river received notoriety in April 1998 for a spill that spread a great amount of slurry (mainly pyrites) and acid waters in a narrow strip along the river course. Groundwaters and surface waters were sampled to analyse, among other elements, the REEs. Their spatial distribution shows a peak ...
Tópico(s): Heavy Metal Exposure and Toxicity
2004 - Elsevier BV | Environmental Pollution
Damián García‐Olmo, Dolores C. Garcı́a-Olmo, Jesús Ontañón, Esperanza Martínez‐Romero,
Tópico(s): Erythrocyte Function and Pathophysiology
2000 - Elsevier BV | Blood
Regina Alemany, Gabriel Olmos, Jesús A. García‐Sevilla,
The binding of [ 3 H]‐idazoxan in the presence of 10 −6 m (−)‐adrenaline was used to quantitate I 2 imidazoline‐preferring receptors in the rat brain and liver after chronic treatment with various irreversible and reversible monoamine oxidase (MAO) inhibitors. Chronic treatment (7–14 days) with the irreversible MAO inhibitors, phenelzine (1–20 mg kg −1 , i.p.), isocarboxazid (10 mg kg −1 , i.p.), clorgyline (3 mg kg −1 , i.p.) and tranylcypromine (10 mg kg −1 , i.p.) markedly decreased (21–71%) the density of I 2 imidazoline‐ ...
Tópico(s): Receptor Mechanisms and Signaling
1995 - Wiley | British Journal of Pharmacology
Regina Alemany, Gabriel Olmos, Jesús A. García-Sevilla,
Tópico(s): Pharmacological Receptor Mechanisms and Effects
1997 - Springer Science+Business Media | Naunyn-Schmiedeberg s Archives of Pharmacology
M Assumpció Boronat, Gabriel Olmos, Jesús A García‐Sevilla,
Agmatine, the proposed endogenous ligand for imidazoline receptors, has been shown to attenuate tolerance to morphine‐induced antinociception ( Kolesnikov et al. , 1996 ). The main aim of this study was to assess if idazoxan, an α 2 ‐adrenoceptor antagonist that also interacts with imidazoline receptors, could also modulate opioid tolerance in rats and to establish which type of imidazoline receptors (or other receptors) are involved. Antinociceptive responses to opioid drugs were determined by the tail‐ ...
Tópico(s): Receptor Mechanisms and Signaling
1998 - Wiley | British Journal of Pharmacology
B. Arenaz, M. Martín Maestro, Pilar Fernández Hernando, Javier Turnay, Nieves Olmo, Jesús Senén, Javier Gil Mur, M.A. Lizarbe, E. Jorge‐Herrero,
Chemical modification of biological materials used in the manufacture of cardiac valves tends to reduce the relatively high degree of biodegradation and calcification of the implanted bioprostheses. The most widely used treatment to reduce biodegradability of the valves is glutaraldehyde fixation. However, this treatment is potentially toxic and induces tissue calcification. In order to minimize these undesirable effects, we have analyzed the effect of a pre-fixation of endogenous proteoglycans ...
Tópico(s): Dental materials and restorations
2003 - Elsevier BV | Biomaterials
G Saro, Juan Francisco Del Campo, M.J. Jaras, M Anta, José M. Olmos, Jesús González‐Macías, José A. Riancho,
This study was carried out to examine the diagnostic approach to patients with suspected pulmonary embolism (PE) in a university hospital. A retrospective case record review of 251 patients with suspected pulmonary embolism was carried out according to a standard protocol, which looked at the utilisation of imaging techniques and compared clinical diagnoses with a standardised diagnosis established according to current recommendations. Isotopic lung scan was the most commonly used technique (73%), ...
Tópico(s): Atrial Fibrillation Management and Outcomes
1999 - Oxford University Press | Postgraduate Medical Journal
Carmen Valero, José Luis Pérez‐Castrillón, Marı́a T. Zarrabeitia, José L. Hernández, Maria Augusta Alonso, J. del Pino-Montes, José M. Olmos, Jesús González‐Macías, José A. Riancho,
Two polymorphisms of the aromatase and estrogen receptor genes appeared to interact to influence the risk of hip fractures in women. Allelic variants of the aromatase gene have been associated with bone mineral density and vertebral fractures. Our objective was to analyze the relationship between two polymorphisms of the aromatase and estrogen receptor genes and hip fractures. We studied 498 women with hip fractures and 356 controls. A C/G polymorphism of the aromatase gene and a T/C polymorphism ...
Tópico(s): Bone Metabolism and Diseases
2007 - Springer Science+Business Media | Osteoporosis International
María Socorro Fernández García, José Eduardo Martinez, José M. Olmos, Jesús González‐Macías, José L. Hernández,
The aging of the world population is an indicator of improving health worldwide.In developed countries, increased longevity has been accompanied by a so-called "compression of morbidity", that is, although people live longer, they do not spend more years suffering a poor health status.However, hip fracture itself may reduce life expectancy in almost two years and one in five patients will require permanent health care.Epidemiological studies reporting the incidence of hip fracture in Spain are numerous. ...
Tópico(s): Bone health and osteoporosis research
2015 - SciELO | Revista de Osteoporosis y Metabolismo Mineral
Daniel García‐Arribas, Isidre Vilacosta, A. Ortega Candil, Cristina Rodríguez Rey, Carmen Olmos, María Jesús Pérez Castejón, David Vivas, Carlos Nicolás Pérez‐García, Manuel Carnero, Cristina Fernández, Luis Maroto, José Carreras‐Mora,
Objective Infection of valved aortic grafts is a rare entity whose diagnosis remains challenging. Positron emission tomography (PET)/CT has become a criterion for the diagnosis of infective endocarditis (IE) in prosthetic valves, but its role on ascending aortic graft infections remains unclear. This study aims to assess the diagnostic value of PET/CT in patients with valved aortic graft infection. Methods 12 episodes with a valved aortic graft who had undergone a PET/CT due to suspicion of IE were ...
Tópico(s): Infectious Aortic and Vascular Conditions
2018 - BMJ | Heart
José de Jesús Olmos-Espejel, Martha Patricia García de Llasera, Marisol Velasco-Cruz,
This paper describes the development and validation of an analytical methodology to determine the presence of four PAHs: benzo[a]anthracene, benzo[b]fluoranthene, benzo[k]fluoranthene and benzo[a]pyrene in cultures of the green microalgae Selenastrum capricornutum. The metabolites of benzo[a]pyrene (BaP), 4,5-dihydrodiol benzo[a]pyrene, 9,10-dihydrodiol benzo[a]pyrene, 3-hydroxy benzo[a]pyrene and 9-hydroxy benzo[a]pyrene were also included. The methodology consisted of three parts: (1) separation ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2012 - Elsevier BV | Journal of Chromatography A
Martha Patricia García de Llasera, José de Jesús Olmos-Espejel, Gabriel Díaz-Flores, Adriana Montaño-Montiel,
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2015 - Springer Science+Business Media | Environmental Science and Pollution Research
Neville N. Osborne, Claudia Núñez‐Álvarez, Susana del Olmo‐Aguado, Jesús Merrayo-Lloves,
Tópico(s): Mitochondrial Function and Pathology
2016 - Elsevier BV | Mitochondrion
Luis Meseguer‐Olmo, Antonio Jesús Montellano, Teresa Martı́nez, Carlos Martínez, Beatriz Revilla‐Nuin, Marta Roldán, Cristina Mora, María Dolores López-Lucas, T. Fuente,
Therapeutic application of intravenous administered (IV) human bone marrow-derived mesenchymal stem cells (ahMSCs) appears to have as main drawback the massive retention of cells in the lung parenchyma, questioning the suitability of this via of administration. Intraarticular administration (IAR) could be considered as an alternative route for therapy in degenerative and traumatic joint lesions. Our work is outlined as a comparative study of biodistribution of 99mTc-ahMSCs after IV and IAR administration, ...
Tópico(s): Orthopaedic implants and arthroplasty
2016 - Elsevier BV | Nuclear Medicine and Biology
Nieves Quesada-Olmo, María Jesús Jiménez-Martínez, Mercedes Farjas Abadía,
Continuous assessment of the displacement of a high-rise building enables verification that it meets the structural assumptions calculated in the project, and provides additional useful feedback for structural engineers. Unexpected structural responses during the phases of construction, or once the building is in use, can help detect current and future problems, as well as provide cost savings. Furthermore, it contributes to an improved risk management for natural phenomena and can be used to verify ...
Tópico(s): Inertial Sensor and Navigation
2018 - Elsevier BV | Measurement
Irma C. Gavilán-García, Elvira Santos-Santos, Luis Raúl Tovar-Gálvez, Arturo Gavilán-García, Sara Santamaría Suárez, Jesús Olmos,
Amalgamation was heavily used in mining since 1557 in Spanish Colonies. In Mexico and other parts of Latin-America,this process generated tailings which were left aside in the mine backyards. In the valley of Zacatecas, tailings were carried out of the mines due to the run-off from the mountains and contaminated most of the Zacatecan Valley which most important economic activity is agricultural (crop and livestock raising). The main concern in this area is the high level of total mercury found in ...
Tópico(s): Analytical chemistry methods development
2019 - Mexican Chemical Society | Journal of the Mexican Chemical Society
Igor Jukić, Julio Calleja-González, Francesc Cos, Francesco Cuzzolin, Jesús Olmo, Nicolás Terrados, Nenad Njaradi, Roberto Sassi, Bernardo Requena, Luka Milanović, Ivan Krakan, Kostas Chatzichristos, Pedro E. Alcaráz,
In December of 2019, there was an outbreak of a severe acute respiratory syndrome caused by the Coronavirus 2 (SARS-CoV-2 or COVID-19) in China. The virus rapidly spread into the whole World causing an unprecedented pandemic and forcing governments to impose a global quarantine, entering an extreme unknown situation. The organizational consequences of quarantine/isolation are: absence of organized training and competition, lack of communication among athletes and coaches, inability to move freely, ...
Tópico(s): Cardiovascular and exercise physiology
2020 - Multidisciplinary Digital Publishing Institute | Sports
Wenceslao Piedra‐Cascón, Mohammed M. Methani, Nieves Quesada-Olmo, María Jesús Jiménez-Martínez, Marta Revilla‐León,
Abstract Statement of problem Diagnostic stone casts can be digitized by using dental optical scanners based on structured light scanning technology. Nondental structured light scanning scanners could also be used; however, the accuracy of these nondental scanners remains unclear. Purpose The purpose of this in vitro study was to measure the scanning accuracy (trueness and precision) of 3 nondental extraoral structured light scanners. Material and methods A representative maxillary diagnostic cast was obtained ...
Tópico(s): Dental Radiography and Imaging
2020 - Elsevier BV | Journal of Prosthetic Dentistry
Francisco José de Haro-Olmo, Ángel Jesús Varela‐Vaca, José Antonio Álvarez Bermejo,
The research presented aims to investigate the relationship between privacy and anonymisation in blockchain technologies on different fields of application. The study is carried out through a systematic literature review in different databases, obtaining in a first phase of selection 199 publications, of which 28 were selected for data extraction. The results obtained provide a strong relationship between privacy and anonymisation in most of the fields of application of blockchain, as well as a ...
Tópico(s): Privacy, Security, and Data Protection
2020 - Multidisciplinary Digital Publishing Institute | Sensors
Fabio Sarto, Franco M. Impellizzeri, Jörg Spörri, Simone Porcelli, Jesús Olmo, Bernardo Requena, Luís Suárez-Arrones, Amelia Arundale, Johann Bilsborough, Martin Buchheit, Jo Clubb, Aaron J. Coutts, Dustin Nabhan, Lorena Torres-Ronda, Alberto Méndez-Villanueva, Iñigo Mujika, Nicola A. Maffiuletti, Martino V. Franchi,
Tópico(s): Occupational Health and Performance
2020 - Springer Science+Business Media | Sports Medicine
Jesús Olmo, Susana Jato, Jaime Benito, Ignacio Martín Tamayo, Zeevi Dvir,
Based on the limited ability of the human being to voluntarily control submaximal eccentric exertions, previous studies have indicated that isokinetic testing with a combined concentric-eccentric exercise protocol could effectively identify submaximal (feigned) effort in various muscle groups by showing an abnormally high eccentric to concentric ratio (ECR). The objective of this study was to determine the validity and accuracy of an ECR-based isokinetic test in identifying feigned ankle weakness. ...
Tópico(s): Cerebral Palsy and Movement Disorders
2008 - Elsevier BV | Journal of Electromyography and Kinesiology
<span>El doctor en Derecho Pablo Angarita, en su publicación "Seguridad democrática : lo invisible de un régimen político y económico", analiza lo que ha sido la política de seguridad democrática en Colombia en los dos períodos del Gobierno de Álvaro Uribe Vélez. Justificada por múltiples hechos de violencia, la seguridad viene a ser el discurso político que pretende recuperar el orden a cualquier costo. Su estudio parte de los planteamientos críticos e históricos, para desarrollar un tema complejo ...
Tópico(s): Criminal Justice and Penology
2014 - Latin American Social Sciences Institute | URVIO - Revista Latinoamericana de Estudios de Seguridad