Wen Yin, Xingjun Jiang, Jun Tan, Zhaoqi Xin, Quanwei Zhou, Chaohong Zhan, Xianyong Fu, Zhaoping Wu, Youwei Guo, Zhipeng Jiang, Caiping Ren, Guihua Tang,
Tumor mutation burden (TMB) is a useful biomarker to predict prognosis and the efficacy of immune checkpoint inhibitors (ICIs). In this study, we aimed to explore the prognostic value of TMB and the potential association between TMB and immune infiltration in lower-grade gliomas (LGGs). Somatic mutation and RNA-sequencing (RNA-seq) data were downloaded from the Cancer Genome Atlas (TCGA) database. TMB was calculated and patients were divided into high- and low-TMB groups. After performing differential ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2020 - Frontiers Media | Frontiers in Oncology
Zhipeng Jiang, Tao Yang, Chen Li, Jiahang Zou, Hanxu Yang, Qingan Zhang, Yongtao Li,
Abstract Ether‐based electrolytes have high ionic conductivity and good stability toward the lithium metal anode relative to carbonate‐based electrolytes, but they typically exhibit poor oxidation stability (<4 V vs Li + /Li). Most approaches aimed at enhancing the oxidative stability of ether‐based electrolytes, such as “salt‐in‐solvent” and “weakly solvating” strategies, often sacrifice their inherent advantage of high ionic conductivity. Herein, this article proposes a cost‐effective synergistic additive ...
Tópico(s): Advanced battery technologies research
2023 - Wiley | Advanced Functional Materials
Zhipeng Jiang, Pengfei Zhu, Yue Yang, Wei Jin, Guoqiang Zou, Hongshuai Hou, Jiugang Hu, Wei Sun, Xiaobo Ji,
Excessive chemical consumption and its concomitant secondary pollution have become persistent issues in the wet chemical recycling process of spent LiFePO4 batteries (sLFP). In this study, a prospective recycling strategy is proposed based on sustainable proton circulation between organic leachants, extractants, and strippants, whereby expensive organic leachants can be regenerated and secondary pollutants are reduced. The leaching dependence of the sLFP powder on the structure of the organic leachants ...
Tópico(s): Recycling and Waste Management Techniques
2023 - Elsevier BV | Chemical Engineering Journal
Yanwei Sun, Yingai Jin, Zhipeng Jiang, Liang Li,
With its high energy density and long lifespan, li-ion battery (LIB) is now dominating the power source market for portable electronics such as smartphones, laptops, and electric vehicles. However, LIB electrolyte is flammable, and the diaphragm has low stability, making it easy to cause thermal runaway (TR). This paper reviews the research progress on TR propagation characteristics and prevention strategies. The study reviewed the analysis of practical measures of battery management systems, safety ...
Tópico(s): Advanced Battery Materials and Technologies
2023 - Elsevier BV | Engineering Failure Analysis
Xiaole Su, Yuanchao Hu, Liu Wei, Zhipeng Jiang, Chan Qiu, Jie Xiong, Ju Sun,
Abstract The extension of emerging renewable energy sources such as wind and water turbines, solar panels, and the increasing usage of electric vehicles requires the supply and distribution of energy in a small device on local scale and it has created new methods of supplying and selling electricity. Middle buyers and end users can obtain the local energy with the peer‐to‐peer trading method in this large and hierarchical market. This method enables market to manage and exchange the electricity ...
Tópico(s): Smart Grid Security and Resilience
2023 - Wiley | Security and Privacy
Pengfei Zhu, Zhipeng Jiang, Wei Sun, Yue Yang, Debbie S. Silvester, Hongshuai Hou, Craig E. Banks, Jiugang Hu, Xiaobo Ji,
Built-in anionic equilibrium strategy is proposed to recover lithium from spent LiFePO 4 cathodes with high atom economy.
Tópico(s): Recycling and Waste Management Techniques
2023 - Royal Society of Chemistry | Energy & Environmental Science
Jingyao Su, Zhenzhu Cao, Zhipeng Jiang, Guohua Chen, Yuxuan Zhu, Liying Wang, Guorong Li,
Abstract Mg 0.2 Co 0.2 Ni 0.2 Cu 0.2 Zn 0.2 O high entropy oxide (HEO) with outstanding cycling stability and high capacity retention indicates it is a promising anode material for rechargeable lithium‐ion batteries. Rock salt HEO nanofiber has been prepared by electrospinning method. Polyacrylonitrile polymer facilitates the formation of nanowire morphology. The effect of calcination temperature on the phase composition and microstructure evolutions has been investigated. Pure rock salt phase can ...
Tópico(s): Transition Metal Oxide Nanomaterials
2022 - Wiley | International Journal of Applied Ceramic Technology
Zhipeng Jiang, Chen Li, Jisheng Mo, Hanxu Yang, Haiwen Li, Qingan Zhang, Yongtao Li,
Lithium metal anode (LMA) has been regarded as the “Holy grail” among next-generation anode materials, which are severely enslaved to its poor cycling stability. Many problems such as Li dendrites and dead Li are involved in the cycling process, thus a protection strategy with a single function is difficult to achieve long-term stability of LMA. Herein, we developed a cation-anion synergetic additive, cesium triiodide (CsI3), to inhibit Li dendrite growth and eliminate dead Li. The addition of Cs+ ...
Tópico(s): Advanced Battery Technologies Research
2022 - Elsevier BV | Chemical Engineering Journal
Pengju Li, Xiaobo Huang, Zhipeng Jiang, Han Zhang, Pengwei Yu, Xing Lü, Jia Xie,
Tópico(s): Inorganic Chemistry and Materials
2022 - Springer Science+Business Media | Nano Research
Zhipeng Jiang, Jisheng Mo, Chen Li, Haiwen Li, Qingan Zhang, Ziqi Zeng, Jia Xie, Yongtao Li,
Development of advanced high‐voltage electrolytes is key to achieving high‐energy‐density lithium metal batteries (LMBs). Weakly solvating electrolytes (WSE) can produce unique anion‐driven interphasial chemistry via altering the solvating power of the solvent, but it is difficult to dissolve the majority of Li salts and fail to cycle at a cut‐off voltage above 4.5 V. Herein, we present a new‐type WSE that is regulated by the anion rather than the solvent, and the first realize stable cycling of dimethoxyethane ( ...
Tópico(s): Advanced Battery Technologies Research
2022 - Wiley | Energy & environment materials
Abdullah Al Mamun, Mahathir Mohammad Bappy, Ayantha Senanayaka, Jiali Li, Zhipeng Jiang, Zhenhua Tian, Sara Fuller, T. C. Falls, Linkan Bian, Wenmeng Tian,
Tópico(s): Gear and Bearing Dynamics Analysis
2022 - Springer Science+Business Media | The International Journal of Advanced Manufacturing Technology
Zhipeng Jiang, Zehui Hou, Wei Liu, Zhuomin Yu, Zhiqiang Liang, Shuang Chen,
The dysregulated circular RNAs (circRNAs) are linked to progression and chemoresistance in colorectal cancer (CRC). However, the role of circRNA protein tyrosine kinase 2 (circPTK2) in CRC progression and chemoresistance is uncertain. The circPTK2, microRNA (miR)-136-5p, m6A 'reader' protein YTH domain family protein 1 (YTHDF1), β-catenin and cyclin D1 abundances were examined via quantitative reverse transcription PCR or Western blotting. The progression was investigated by cell counting kit-8 (CCK-8), ...
Tópico(s): Cancer Mechanisms and Therapy
2022 - Taylor & Francis | Bioengineered
Liang Li, Zhipeng Jiang, Xiangcai Zou, Tengfei Hao,
Exosomal circular RNAs (circRNAs) can act as biomarkers and play crucial roles in colorectal cancer (CRC) and radiosensitivity. The aim of this study was to explore the functions and regulatory mechanism of exosomal circRNA intraflagellar transport 80 (circ_IFT80) in tumorigenesis and radiosensitivity of CRC.Exosomes were detected using transmission electron microscopy (TEM). Protein levels were determined by Western blot assay. The expression of circ_IFT80, microRNA-296-5p (miR-296-5p) and musashi1 ( ...
Tópico(s): Extracellular vesicles in disease
2021 - Dove Medical Press | Cancer Management and Research
Zhipeng Jiang, Ziqi Zeng, Baoyu Zhai, Xing Li, Wei Hu, Han Zhang, Shijie Cheng, Jia Xie,
Lithium metal battery (LMB) is regarded as a rising star for next generation high energy density batteries. However, there is still a great challenge to achieve stable cycling of high-voltage LMBs, especially under practical conditions. Herein, we report a fluorobenzene-based (FB-based) diluted highly concentrated carbonate electrolyte with significantly improved physical and electrochemical properties. Employing FB as the diluent not only reduces the viscosity, density and cost of highly concentrated ...
Tópico(s): Thermal Expansion and Ionic Conductivity
2021 - Elsevier BV | Journal of Power Sources
Pengju Li, Zhipeng Jiang, Xiaobo Huang, Xing Lü, Jia Xie, Shijie Cheng,
Electrolyte additives have an important impact on the cycling stability of sodium metal batteries, but their applications are severely impeded by the poor compatibility with different electrolytes. Herein, rational incorporation of nitro groups on fullerene (C60) cage yields nitrofullerene (C60(NO2)6) as an effective additive, which displays high compatibility with different electrolytes and can enable highly reversible and dendrite-free plating/stripping of sodium metal anodes (SMAs). In-situ optical ...
Tópico(s): Inorganic Chemistry and Materials
2021 - Elsevier BV | Nano Energy
Zhipeng Jiang, Yiyang Liu, Zhen-En Shao, Ko-Wei Huang,
Image recognition has been applied to many fields, but it is relatively rarely applied to medical images. Recent significant deep learning progress for image recognition has raised strong research interest in medical image recognition. First of all, we found the prediction result using the VGG16 model on failed pneumonia X-ray images. Thus, this paper proposes IVGG13 (Improved Visual Geometry Group-13), a modified VGG16 model for classification pneumonia X-rays images. Open-source thoracic X-ray ...
Tópico(s): AI in cancer detection
2021 - Multidisciplinary Digital Publishing Institute | Applied Sciences
Zhipeng Jiang, Ziqi Zeng, Han Zhang, Li Yang, Wei Hu, Xinmiao Liang, Jiwen Feng, Chuang Yu, Shijie Cheng, Jia Xie,
Developing low cost, yet high-voltage electrolyte is significant to improve the energy density and practicability of lithium metal batteries (LMBs). Low concentration electrolyte has significant merits in terms of cost and viscosity; however, their poor compatibility with high-voltage LMBs hinders its applications. Here, we develop a diluted low concentration electrolyte by replacing solvating cosolvent with a non-solvating cosolvent to facilitate the interaction between BF4- and Li+, resulting in ...
Tópico(s): Advanced Battery Technologies Research
2021 - Cell Press | iScience
Zhilong Han, Shuping Li, Ruoyu Xiong, Zhipeng Jiang, Mengjun Sun, Wei Hu, Linfeng Peng, Renjie He, Huamin Zhou, Chuang Yu, Shijie Cheng, Jia Xie,
Abstract High‐energy density and ultra‐long cycling lifespan are of great significance in pursuit of practical lithium–sulfur (Li‐S) batteries, in which the construction of ultrathick, high‐areal‐capacity, and stable‐cycling sulfur cathodes remains challenging. Here, a unique layered reinforced concrete structure (LRCS) is reported by integrating an ice‐template method with incorporating carbon fibers in the thick electrodes for Li‐S batteries. The LRCS enables aligned through‐channel structure and ...
Tópico(s): Advanced Battery Technologies Research
2021 - Wiley | Advanced Functional Materials
Xiangcai Zou, Zhipeng Jiang, Li Liang, Zong-hai Huang,
Cancer-targeted drug delivery systems based on nanoparticles (NPs) have been considered promising therapies. In this study, we developed a pH-responsive smart NPs drug delivery system using silk fibroin (SF), selenium nanoparticles (Se NPs), fingolimod (FTY720), and heptapeptide (T7). The prepared FTY720@T7-SF-Se NPs were spheres with an average diameter of 120 nm, which would contribute to the enhanced permeability and retention effects in tumour regions. The encapsulation efficiency (EE) of the FTY720@ ...
Tópico(s): Phytochemical compounds biological activities
2021 - Informa | Artificial Cells Nanomedicine and Biotechnology
Zhipeng Jiang, Qinwen Tai, Xiaojun Xie, Zehui Hou, Wei Liu, Zhuomin Yu, Zhiqiang Liang, Shuang Chen,
Colorectal cancer (CRC) is a common malignant tumor. Circular RNAs (circRNAs) have been reported to take part in the progression of CRC. However, the functions of circ_0084615 in CRC development are still undefined. In this study, we aimed to explore the functions and underlying mechanisms of circ_0084615 in CRC.qRT-PCR, western blot assay and IHC assay were utilized for the levels of circ_0084615, miR-599, ONECUT2 or EIF4A3. 5-ethynyl-2'-deoxyuridine (EdU) assay and colony formation assay were conducted ...
Tópico(s): Cancer-related molecular mechanisms research
2021 - BioMed Central | Journal of Experimental & Clinical Cancer Research
Zhipeng Jiang, Zehui Hou, Wei Liu, Zhuomin Yu, Zhiqiang Liang, Shuang Chen,
Recently, circular RNA was reported to be a significant participant in the development of tumorigenesis, including colorectal cancer. Therefore, we aimed to clarify the precise role of circ-keratin 6C (circ-KRT6C) in colorectal cancer progression. The relative expression levels of circ-KRT6C, microRNA-485-3p (miR-485-3p), and programmed cell death receptor ligand 1 (PDL1) were analyzed by real-time quantitative polymerase chain reaction and Western blot assays. The proliferation was assessed by cell ...
Tópico(s): Genomics, phytochemicals, and oxidative stress
2021 - American Society for Pharmacology and Experimental Therapeutics | Journal of Pharmacology and Experimental Therapeutics
Zhipeng Jiang, Hao Hu, Wenli Hu, Zehui Hou, Wei Liu, Zhuomin Yu, Zhiqiang Liang, Shuang Chen,
Abstract Aim Previous studies have reported that circular RNA (circRNA) is associated with the pathogenesis of CRC. This study was designed to reveal the mechanism of circ-ring finger protein 121 (circ-RNF121) in colorectal cancer (CRC). Materials and methods The levels of circ-RNF121, microRNA-1224-5p (miR-1224-5p) and forkhead box M1 (FOXM1) were determined by quantitative real-time polymerase chain reaction (qRT-PCR). Protein level was detected by western blot. Cell proliferation was analyzed by 3-( ...
Tópico(s): MicroRNA in disease regulation
2021 - BioMed Central | Cancer Cell International
Zhipeng Jiang, Ziqi Zeng, Wei Hu, Zhilong Han, Shijie Cheng, Jia Xie,
Lithium-sulfur (Li-S) battery, with their inherent advantages of high-energy density, low-cost, and eco-friendliness, shows promise as next-generation energy storage system. However, the practical Li-S batteries are far from achieving high-energy density and stable operation, because of the irreversible loss of active materials in both Li anode and S cathode. Herein, a modified diluted high concentration electrolyte (MDHCE) was designed for the practical Li-S batteries, which achieves a high energy ...
Tópico(s): Advanced Battery Technologies Research
2021 - Elsevier BV | Energy storage materials
Ziqi Zeng, Xin Chen, Mengjun Sun, Zhipeng Jiang, Wei Hu, Chuang Yu, Shijie Cheng, Jia Xie,
The design of solid polymer electrolytes (SPE) with high ionic conductivity and excellent mechanical properties is challenging because these two properties are often conflicting. To achieve both, a reaction-controlled strategy is proposed based on the nanophase separation of an ionic transport pathway and a supporting matrix to balance ionic mobility and mechanical properties. Specifically, an elastic epoxy polymer electrolyte (eEPE), synthesized via two-step polymerization, combines outstanding mechanical ...
Tópico(s): Advanced Battery Technologies Research
2021 - American Chemical Society | Nano Letters
Zhipeng Jiang, Zehui Hou, Liang Li, Wei Liu, Zhuomin Yu, Shuang Chen,
Abstract Background Exosomes contain many functional RNAs, including circular RNA (circRNA), which are critical for cancer progression. However, the role of exosomal circEPB41L2 in colorectal cancer (CRC) remains unclear. Methods Exosomes were isolated from plasma and cells. The characteristics of the exosomes were identified using transmission electron microscopy and nanoparticle tracking analysis. The protein levels of exosome markers and PTEN/AKT‐related markers were measured using Western blot ...
Tópico(s): Extracellular vesicles in disease
2021 - Wiley | European Journal of Clinical Investigation
Zhipeng Jiang, Wen Yin, Hecheng Zhu, Jun Tan, Youwei Guo, Zhaoqi Xin, Quanwei Zhou, Yudong Cao, Zhaoping Wu, Yirui Kuang, Can Li, Dongcheng Xie, Hailong Huang, Ming Zhao, Xingjun Jiang, Lei Wang, Caiping Ren,
Abstract Methyltransferase-like 7B (METTL7B) is a member of the methyltransferase-like protein family that plays an important role in the development and progression of tumors. However, its prognostic value and the correlation of METTL7B expression and tumor immunity in some cancers remain unclear. By analyzing online data, we found that METTL7B is abnormally overexpressed in multiple human tumors and plays an important role in the overall survival (OS) of patients with 8 cancer types and disease- ...
Tópico(s): Epigenetics and DNA Methylation
2021 - BioMed Central | Cancer Cell International
Dajin Liu, Zhipeng Jiang, Wei Zhang, Jingqi Ma, Jia Xie,
Chitosan is employed as a carbon precursor to fabricate micron-scale interconnected SiO x /NC spheres that exhibit excellent lithium storage performance.
Tópico(s): Supercapacitor Materials and Fabrication
2020 - Royal Society of Chemistry | RSC Advances
Taicheng Zhou, Lili Wu, Ning Ma, Fuxin Tang, Zhuomin Yu, Zhipeng Jiang, Yingru Li, Zhen Zong, Kunpeng Hu,
Abstract SRY-box transcription factors (SOXs) are effective inducers for the formation of stem-like phenotypes. As a member of SOX family, SOX9 (SRY-box transcription factor 9) has been reported to be highly expressed and exert oncogenic functions in multiple human cancers. In this study, we hypothesized that SOX9 could regulate the function of cancer stem/initiating cells (CSCs) to further facilitate the progression of colorectal cancer (CRC). Then, stable transfection of shRNAs was used to silence ...
Tópico(s): RNA modifications and cancer
2020 - Springer Nature | Cell Death and Disease
Zhipeng Jiang, Yuming Zhao, Xing Lü, Jia Xie,
The development of high-performance batteries is inseparable from the exploration of new materials. Among them, fullerene C60 as an allotrope of carbon has many unique properties that are beneficial for battery applications, including precise structure, controllable derivatization, good solubility, and rich redox chemistry. In this review, we summarize the recent progress of fullerene-based materials in the field of rechargeable batteries and the key issues that need to be solved in the future application ...
Tópico(s): Fullerene Chemistry and Applications
2020 - Elsevier BV | Journal of Energy Chemistry
Zhipeng Jiang, Jin Liu, Ziqi Zeng, Jia Xie,
A facile strategy was developed to stablize 3D hosts for lithium metal anodes in carbonate electrolytes, which enables lithium metal batteries with improved Coulombic efficiency (∼99%) and prolonged cycle lifespan (96% retention over 300 cycles) under the conditions of high areal loading (3 mA h cm-2) and low N/P ratio (4).
Tópico(s): Thermal Expansion and Ionic Conductivity
2020 - Royal Society of Chemistry | Chemical Communications