Xiaomei Jin, Xifeng Wu, Jack A. Roth, Christopher I. Amos, Terri M. King, Cynthia D. Branch, S E Honn, Margaret R. Spitz,
... with the Pro/Pro p53 genotype Get access Xiaomei Jin, Xiaomei Jin 1Departments of Thoracic and Cardiovascular Surgery, The University ...
Tópico(s): Cancer, Lipids, and Metabolism
1995 - Oxford University Press | Carcinogenesis
Xiaomei Jin, Li Wan, You-Kan Zhang, Guangcheng Hu, Michael E. Schaepman, J.G.P.W. Clevers, Zhongbo Su,
The spatial distribution of vegetation in the Qilian Mountain area was quantified with remote sensing data. The MODIS NDVI values for June, July, August and September are the best indicators for the vegetation growth during a year in this area and thus were used in this study. The results obtained by analysing NDVI data for seven years from 2000 to 2006 clearly indicated that elevation and aspect, as a proxy for precipitation and temperature, are two very important factors for the vertical distribution ...
Tópico(s): Environmental Changes in China
2009 - Taylor & Francis | International Journal of Remote Sensing
Xiaomei Jin, Guangcheng Hu, Wenmei Li,
The relationship between vegetation growth and groundwater in arid areas is one of the most actively researching topics in ecohydrology. On account of little precipitation, the oasis is the only form of sustenance for living and economic development, for the local people in the arid areas of Northwest China. During recent years, with the increase of water consumption in the middle stream area of the Heihe river basin, the incoming water has decreased gradually and the area of the Ejina oasis in ...
Tópico(s): Hydrology and Watershed Management Studies
2008 - Elsevier BV | Earth Science Frontiers
Xiaomei Jin, Michael E. Schaepman, J.G.P.W. Clevers, Zhongbo Su, Guangcheng Hu,
In arid regions, an oasis plays an important role. It is nearly the only support of living and economic development for the local people. In recent years, the recession of the oasis areas appeared to be significant in Northwest China. It caused a series of environmental problems and part of the area even became the source of sandstorms. In this article, the long-term vegetation change of the Ejina Oasis, which is located in the downstream area of the Heihe River basin, was analyzed based on remote ...
Tópico(s): Rangeland Management and Livestock Ecology
2010 - Taylor & Francis | Arid Land Research and Management
Xiaomei Jin, Li Wan, You‐Kuan Zhang, Zhongqi XUE, Ying Yin,
The relationship between vegetation growth and groundwater in arid areas is one of the most active research topics in ecohydrology. Due to less precipitation, the vegetation growth has close relationship with groundwater in northwest arid inland areas of China. Research on the ecological effect of groundwater from large scale has important significance in eco-environment recovery and protection. In this study, we investigated the relationship between the vegetation growth and the depth to water ...
Tópico(s): Environmental Changes in China
2007 - Elsevier BV | Earth Science Frontiers
Qiong Long, Weiwei Huang, Yufeng Yao, Xu Yang, Wenjia Sun, Xiaomei Jin, Yang Li, Xiaojie Chu, Cunbao Liu, Zhikang Peng, Yanbing Ma,
We sought to develop an IL-33 vaccine and evaluate its efficacy in a mouse model of asthma. The full-length molecules of putative mature IL-33 were inserted into the immunodominant epitope region of hepatitis B core antigen using gene recombination techniques. The expressed chimeric protein presented as virus-like particles (VLPs) under observation using an electron microscopy. To investigate immunization characteristics of the VLPs, mice were immunized by using different doses, adjuvants, and routes. ...
Tópico(s): Immune Cell Function and Interaction
2014 - Taylor & Francis | Human Vaccines & Immunotherapeutics
Weiwei Huang, Yufeng Yao, Qiong Long, Xu Yang, Wenjia Sun, Cunbao Liu, Xiaomei Jin, Yang Li, Xiaojie Chu, Bin Chen, Yanbing Ma,
Acinetobacter baumannii is considered the prototypical example of a multi- or pan- drug-resistant bacterium. It has been increasingly implicated as a major cause of nosocomial and community-associated infections. This study proposed to evaluate the efficacy of immunological approaches to prevent and treat A. baumannii infections.Mice were immunized with outer membrane vesicles (OMVs) prepared from a clinically isolated multidrug-resistant strain of A. baumannii. Pneumonia and sepsis models were used ...
Tópico(s): Escherichia coli research studies
2014 - Public Library of Science | PLoS ONE
Xiaomei Jin, Renhong Guo, Wei Xia,
Evapotranspiration is a major loss flux of the water balance in arid and semi-arid areas. The estimation of actual evapotranspiration has significance for hydrological and environmental purposes. The Surface Energy Balance System (SEBS) algorithm was applied to estimate actual evapotranspiration in the Qaidam Basin and its eight hydrological sub-regions, Northwest China. There were 3,036 cloud-free and atmospherically corrected MODIS satellite images from 2001 to 2011 used in the SEBS algorithm to ...
Tópico(s): Climate variability and models
2013 - Multidisciplinary Digital Publishing Institute | Remote Sensing
Xiaomei Jin, Rob Bookstein, Ken N. Wills, Jenny B. Avanzini, Van Tsai, Drake LaFace, Gaby Terracina, Bin Shi, Loretta L. Nielsen,
Progressive growth and metastasis of solid tumors require angiogenesis, or the formation of new blood vessels. Endostatin is a 20-kDa carboxy-terminal fragment of collagen XVIII that has been shown to inhibit endothelial cell proliferation and tumor angiogenesis. Replication-deficient recombinant adenovirus (rAd) vectors were constructed, which encoded secreted forms of human and mouse endostatin (HECB and MECB, respectively), and, as a control, human alkaline phosphatase (APCB). Accumulation of endostatin ...
Tópico(s): Cell Adhesion Molecules Research
2001 - Springer Nature | Cancer Gene Therapy
Xiaomei Jin, Jintao Liu, Songtao Wang, Wei Xia,
This article discusses an evaluation of Moderate Resolution Imaging Spectroradiometer (MODIS) time-series data for monitoring vegetation variation in Qaidam Basin, Northwest China. In this study, 16 day composite 250 m normalized difference vegetation index (NDVI) products (MOD13Q1) acquired from 2000 to 2011 were processed to determine vegetation cover fraction (VCF) for detecting the annual dynamics of different types of vegetation cover in the basin and the products were validated by comparing field ...
Tópico(s): Species Distribution and Climate Change
2016 - Taylor & Francis | International Journal of Remote Sensing
Xianjun Fang, Xiaomei Jin, Hong-Ji Xu, Lin Liu, Hong-Qi Peng, David Hogg, Jack A. Roth, Yinhua Yu, Fengji Xu, Robert C. Bast, Gordon B. Mills,
The RB and p16INK4A tumor suppressor genes function in the same pathway of cell cycle control. Previous evidence indicates that the p16INK4A gene is transcriptionally repressed by the RB gene product, pRB. In this study using human ovarian cancer cell lines, we found that RB protein and mRNA were expressed at higher levels in cell lines lacking p16 than in those with normal p16. Since this suggests a potential role of p16 in regulating the cellular level of pRB, we studied the effect of wild-type ...
Tópico(s): Cancer Research and Treatments
1998 - Springer Nature | Oncogene
Aaron Frimerman, Peter J. Welch, Xiaomei Jin, Neal Eigler, Soonpin Yei, James S. Forrester, Hidehiko Honda, Raj Makkar, Jack R. Barber, Frank Litvack,
Background —Stent-induced coronary restenosis is a major clinical and public health problem. Proliferating cell nuclear antigen (PCNA) is an important regulator of cell division, and blocking of its expression after angioplasty may limit intimal proliferation. Methods and Results —We cloned the porcine PCNA gene and constructed a chimeric hammerhead ribozyme to a segment of the gene with human homology. In vitro studies with both cultured porcine and human vascular smooth muscle cells demonstrated ...
Tópico(s): Glycosylation and Glycoproteins Research
1999 - Lippincott Williams & Wilkins | Circulation
Min Chen, Yanling Ma, Huichao Chen, Jie Dai, Lijuan Dong, Chaojun Yang, Youfang Li, Hongbing Luo, Renzhong Zhang, Xiaomei Jin, Li Yang, Allen Ka Loon Cheung, Manhong Jia, Zhizhong Song,
Background Yunnan has the greatest share of reported human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) cases in China. In recent years, HIV prevalence and incidence remained stubbornly high in men who have sex with men (MSM). To follow the dynamics of the HIV-1 epidemic among MSM, HIV-1 genetic characteristics and genetic transmission networks were investigated. Methods Blood samples from 190 newly diagnosed HIV-1 cases among MSM were continuously collected at fixed sites ...
Tópico(s): HIV/AIDS drug development and treatment
2018 - Public Library of Science | PLoS ONE
Min Chen, Yanling Ma, Huichao Chen, Jie Dai, Hongbing Luo, Chaojun Yang, Lijuan Dong, Xiaomei Jin, Min Yang, Li Yang, Lijun Song, Manhong Jia, Zhizhong Song,
The characteristics of recent HIV infections can provide the information about the dynamics of HIV transmission. Yunnan is one of the provinces hardest-hit by HIV-1 in China. To further understand the characteristics of the HIV-1 epidemic in Yunnan, we analyzed the prevalence of recent HIV-1 infections among newly diagnosed cases, identified the associated factors and explored the spatial distribution of recent HIV-1 infections.Residual plasma samples from HIV-1 diagnostic tests were preserved. ...
Tópico(s): HIV Research and Treatment
2019 - BioMed Central | BMC Public Health
Xiaomei Jin, Xiaoqian Zhu, Yang Xue,
A regional framework for a spatial and temporal distributed assessment of time series trends in the hydrological variable and its related ecological factors of an arid area was presented in this research. To achieve this, we tested the Surface Energy Balance System (SEBS) algorithm for estimating evapotranspiration (ET) in regional scale and the result was further validated by water budget. The ET assessment was applied for the Yinchuan and Weining (YW) Plains (China), the upstream areas of the Yellow ...
Tópico(s): Urban Heat Island Mitigation
2019 - Taylor & Francis | International Journal of Remote Sensing
Min Chen, Yanling Ma, Huichao Chen, Jie Dai, Hongbing Luo, Chaojun Yang, Lijuan Dong, Xiaomei Jin, Min Yang, Li Yang, Lijun Song, Zhizhong Song, Manhong Jia,
As a gateway for HIV-1 in China, Yunnan has experienced dramatic changes in HIV-1 epidemics, during which HIV-1 genotypes have become complex. To track dynamic changes in HIV-1 genotypes, an HIV-1 molecular epidemiological study was implemented in the recently infected population in Yunnan.From 6,357 HIV-1-positive samples diagnosed during the first half of 2015 in Yunnan, 586 samples were identified as recent infections with BED-capture enzyme immunoassay (CEIA) and were subjected to phylogenetic ...
Tópico(s): HIV/AIDS drug development and treatment
2019 - BioMed Central | BMC Infectious Diseases
Min Chen, Qiongmei Zhu, Hui Xing, Huichao Chen, Xiaomei Jin, Lijuan Dong, Jie Dai, Min Yang, Cuiyun Yang, Manhong Jia, Yanling Ma,
Abstract HIV-1 drug resistance can compromise the effectiveness of antiretroviral therapy (ART). A survey of pretreatment HIV-1 drug resistance (PDR) was conducted in Lincang Prefecture of Yunnan Province. From 372 people living with HIV/AIDS initiating ART for the first time during 2017–2018, 322 pol sequences were obtained, of which 11 HIV-1 strain types were detected. CRF08_BC (70.2%, 226/322) was the predominant strain, followed by URF strains (10.6%, 34/322). Drug resistance mutations (DRMs) were ...
Tópico(s): HIV/AIDS Research and Interventions
2020 - Cambridge University Press | Epidemiology and Infection
Yajuan Han, Xiaoqing Wu, Tao Luo, Chun Qing, Qike Yang, Xiaomei Jin, Nana Liu, Wu Su, Changdong Su,
It is worth highlighting that, for the first time to the best of our knowledge, vertical profiles of atmospheric parameters and $C_n^2$ were measured at Lhasa, south of the Tibetan Plateau, using balloon-borne radiosondes. Based on the measurements, two new statistical models (Lhasa HMN and Lhasa Dewan) for estimating turbulence strength are proposed. Attention has been paid to evaluate the reliability of the two models to reconstruct vertical profiles of $C_n^2$ from a statistical perspective. The ...
Tópico(s): Optical Wireless Communication Technologies
2020 - Optica Publishing Group | Journal of the Optical Society of America A
The Three-River Headwaters Region (TRHR) is an area of crucial significance for the ecological security of China. Owing to dramatic climate change and human activities driven by a series of ecological restoration projects, the ecological environment and vegetation have changed drastically in recent years. However, our knowledge of the current state and driving force of the change in the entire region is limited. This study mapped the spatiotemporal changes in vegetation coverage and quantitatively ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2021 - Elsevier BV | Ecological Indicators
Shen Qu, Zheming Shi, Xiangyang Liang, Guangcai Wang, Xiaomei Jin,
Tópico(s): Geochemistry and Geologic Mapping
2021 - Springer Science+Business Media | Environmental Earth Sciences
Xiaomei Jin, Michael E. Schaepman, J.G.P.W. Clevers, Zhongbo Su,
Evapotranspiration (ET) plays an important role in the hydrological cycle and it is essential to estimate ET accurately for the evaluation of available water resources. This is most important in arid and semi‐arid regions. In this paper, the long‐term changes in daily ET in the semi‐arid Zhangye Basin in northwest China and its impact factors were studied. The spatial distribution of ET was assessed by using the Surface Energy Balance System (SEBS). Cloud‐free National Oceanic and Atmospheric Administration ...
Tópico(s): Climate variability and models
2009 - Taylor & Francis | International Journal of Remote Sensing
Yangxiao Zhou, Zhi Yang, Danrong Zhang, Xiaomei Jin, Jun Zhang,
Two river catchments, the Huangfuchuan and the Hailiutu, located in the same climate zone in the Erdos Plateau, China, have distinctly different flow regimes. This study systematically compared differences between the flow regimes of these two catchments using several statistical methods, and analysed the possible causes. The variations in yearly, monthly and daily mean discharges were found to be much greater in the Huangfuchuan catchment than in the Hailiutu catchment. Preliminary analysis indicated ...
Tópico(s): Soil erosion and sediment transport
2014 - Taylor & Francis | Hydrological Sciences Journal
Difei Li, Huichao Chen, Huilan Li, Yanling Ma, Lijuan Dong, Jie Dai, Xiaomei Jin, Min Yang, Zhijun Zeng, Pengyan Sun, Zhizhong Song, Min Chen,
HIV drug resistance increased with the widespread use of antiretroviral drugs, and posed great threat to antiretroviral therapy (ART). Pu'er Prefecture, lying in the southwest of Yunnan Province, China, borders Myanmar, Laos and Vietnam, is also the area where AIDS was discovered earlier, however, in which there has been no information on HIV drug resistance.A cross-sectional survey of pretreatment drug resistance (PDR) was conducted in Pu'er Prefecture in 2021. Partial pol gene sequences were obtained ...
Tópico(s): HIV Research and Treatment
2022 - BioMed Central | BMC Infectious Diseases
Cuicui Bi, Chun Qing, Pengfei Wu, Xiaomei Jin, Qing Liu, Xianmei Qian, Wenyue Zhu, Ningquan Weng,
Optical turbulence strongly affects different types of optoelectronic and adaptive optics systems. Systematic direct measurements of optical turbulence profiles [Cn2(h)] are lacking for many climates and seasons, particularly in marine environments, because it is impractical and expensive to deploy instrumentation. Here, a backpropagation neural network optimized using a genetic algorithm (GA-BP) is developed to estimate atmospheric turbulence profiles in marine environments which is validated against ...
Tópico(s): Advanced Fiber Optic Sensors
2022 - Multidisciplinary Digital Publishing Institute | Remote Sensing
Dakang Wang, Yulin Zhan, Tao Yu, Yan Liu, Xiaomei Jin, Xinyu Ren, Xinran Chen, Qixin Liu,
Using Surface Energy Balance System (SEBS) to estimate actual evapotranspiration (ET) on a regional scale generally uses gridded meteorological data by interpolating data from meteorological stations with mathematical interpolation. The heterogeneity of underlying surfaces cannot be effectively considered when interpolating meteorological station measurements to gridded data only by mathematical interpolation. This study aims to highlight the improvement of modeled meteorological data from the Weather ...
Tópico(s): Hydrology and Watershed Management Studies
2019 - Multidisciplinary Digital Publishing Institute | Water
Xiaomei Jin, Yamin Wang, Xiaojing Li, Xianxing Tan, Zhigang Miao, Yuanyuan Chen, Ronald C. Hamdy, Balvin H.L. Chua, Jiming Kong, Heqing Zhao, Xingshun Xu,
Tópico(s): Calpain Protease Function and Regulation
2015 - Springer Science+Business Media | Neurotoxicity Research
Yuying Zhang, Jie Dai, Zhengxu Li, Yanling Ma, Huichao Chen, Lijuan Dong, Xiaomei Jin, Min Yang, Zhijun Zeng, Pengyan Sun, An-Yan Hu, Min Chen,
Background The China-Myanmar border area is considered a hot spot of active HIV-1 recombination in Southeast Asia. To better understand the characteristics of HIV-1 transmission in this area, a cross-sectional HIV-1 molecular epidemiological survey was conducted in Baoshan Prefecture of Yunnan Province. Methods In total, 708 newly reported HIV-1 cases in Baoshan Prefecture from 2019 to 2020 were included in this study. HIV-1 gag , pol and env genes were sequenced, and the spatial and demographic distributions ...
Tópico(s): HIV/AIDS drug development and treatment
2022 - Public Library of Science | PLoS ONE
Peng He, Hui Li, Jin Sun, Xiaomei Zhang, Jin‐Song Gong, Jin‐Song Shi, Zhenghong Xu,
Microbial hydroxylation reaction has greatly enriched the number of steroids and created many meaningful new compounds. The dihydroxylation of dehydroepiandrosterone (DHEA) by filamentous fungi produces an important product 3β,7α,15α-trihydroxy-5-androstene-17-one (7α,15α-diOH-DHEA), which can be used as a key intermediate for the synthesis of contraceptive drospirenone. The introduction of microbial hydroxylation reaction reduces the traditional chemical synthesis process by 4 steps and greatly improves ...
Tópico(s): Pharmacogenetics and Drug Metabolism
2022 - Elsevier BV | The Journal of Steroid Biochemistry and Molecular Biology
Shen Qu, Guangcai Wang, Zheming Shi, Zejun Zhu, Xianbin Wang, Xiaomei Jin,
Tópico(s): Groundwater and Watershed Analysis
2022 - Springer Science+Business Media | Mine Water and the Environment
Da-Ming Wang, Lei Sun, Wenjing Sun, Fengjie Cui, Jin‐Song Gong, Xiaomei Zhang, Jin‐Song Shi, Zhenghong Xu,
The membrane-bound glucose dehydrogenase (mGDH) is a rate-limiting enzyme for the industrial production of 2-keto-d-gluconic acid (2KGA) from glucose. In this study, mGDH was firstly purified from a 2KGA industrial producing strain Pseudomonas plecoglossicida JUIM01. The purified mGDH exhibited a specific activity of 16.85 U/mg and was identified as monomeric membrane-bound PQQ-dependent dehydrogenase with a molecular mass of ~87 kDa. The Km and Vmax value of d-glucose were 0.042 mM and 14.620 μM/min, ...
Tópico(s): Biochemical Acid Research Studies
2018 - Elsevier BV | International Journal of Biological Macromolecules