Sandrina Nunes, Dalila Alves, Patrícia Barreto, Miguel Raimundo, Maria Luz Cachulo, Cláudia Farinha, Inês Laíns, João Rodrigues, Carlos Vinícius Dias de Almeida, Luísa Ribeiro, João Figueira, Lèlita Santos, Rufino Silva,
This study aimed to characterize the association of lifestyle and nutritional risk profiles with age-related macular degeneration (AMD) in two subpopulations with differing AMD prevalence. This case-control study (n = 1992) included 768 patients with AMD and 1224 age- and sex-matched participants without AMD with a single visit at a primary health care unit. Enrolled participants completed a validated lifestyle and food frequency questionnaire. A score to measure adherence to the Mediterranean diet ( ...
Tópico(s): Retinal Imaging and Analysis
2018 - Elsevier BV | Nutrition

Gabriela Ferreira Paduani, Guilherme de Assis Barbosa, João Carlos Rodrigues de Morais, Juliana Carvalho Penha Pereira, Marina Fernandes Almeida, Marília Martins Prado, Natália Bicalho Civinelli de Almeida, Melicégenes Ambrósio Ribeiro,
É preocupante o crescimento do consumo de substâncias psicoativas entre a população, o que constitui um grave problema de saúde pública. Entre as substâncias psicoativas, o álcool e o tabaco merecem destaque, pois são drogas lícitas e socialmente aceitas. Este estudo buscou estabelecer a prevalência do uso de bebidas alcoólicas e cigarros entre estudantes da Faculdade de Medicina da Universidade Federal de Uberlândia (Famed/UFU), bem como caracterizar as situações propícias, a freqüência, a auto- ...
Tópico(s): Health and Lifestyle Studies
2008 - Associção Brasileira de Educação Médica | Revista Brasileira de Educação Médica

Norma do Nascimento Batista, Emílio Lèbre La Rovere, João Carlos Rodrigues Aguiar,
Tópico(s): Sustainable Building Design and Assessment
2010 - Elsevier BV | Energy and Buildings

Henrique Melo de Campos Gurgel, Alberto Tesconi Croci, Henrique Amorim Cabrita, José Ricardo Negreiros Vicente, Marcos de Camargo Leonhardt, João Carlos Rodrigues,
In a study of the acetabular component in total hip arthroplasty, 20 hips were operated on using imageless navigation and 20 hips were operated on using the conventional method. The correct position of the acetabular component was evaluated with computed tomography, measuring the operative anteversion and the operative inclination and determining the cases inside Lewinnek's safe zone. The results were similar in all the analyses: a mean anteversion of 17.4° in the navigated group and 14.5° in the ...
Tópico(s): Hip disorders and treatments
2013 - Elsevier BV | The Journal of Arthroplasty

Gabriela Klein Couto, Bruna Silveira Pacheco, Victoria Mascarenhas Borba, João Carlos Rodrigues, Thaís Larré Oliveira, Natália Vieira Segatto, Fabiana K. Seixas, Thiago V. Acunha, Bernardo A. Iglesias, Tiago Collares,
Photodynamic therapy (PDT) is an expanding treatment modality due to its minimally invasive localized activity and few adverse effects. This therapy requires photosensitive compounds, which have high sensitivity to light exposure. Thus, in this work, the in vitro antitumor activity of meso-tetra(3- and 4-pyridyl)porphyrins (3-TPyP and 4-TPyP) in metastatic melanoma cell (WM1366 line) and non-tumoral Ovarian lineage Chinese Hamister (CHO) was evaluated using photodynamic process. Cell viability tests, ...
Tópico(s): Porphyrin and Phthalocyanine Chemistry
2019 - Elsevier BV | Journal of Photochemistry and Photobiology B Biology

Gabriela Klein Couto, João Carlos Rodrigues, Bruna Silveira Pacheco, Lucas Damé Simões, Júlia Damé Fonseca Paschoal, Fabiana K. Seixas, Thiago V. Acunha, Bernardo A. Iglesias, Tiago Collares,
Tetra-cationic porphyrins with peripheral Pt (II) -bipyridyl complexes demonstrated a potential as photosensitizers to be used in photodynamic therapy (PDT). First-line transition metals, such as zinc (II), copper (II) and nickel (II), can be incorporated into the porphyrin nucleus, making this molecule more selective and more effective for this therapy in combating to tumor cells, such as metastatic melanoma. We characterized these derivatives to verify the improvement in selectivity of platinum (II) ...
Tópico(s): Metal complexes synthesis and properties
2020 - Elsevier BV | Photodiagnosis and Photodynamic Therapy

Gislene Salim Rodrigues, João Carlos Espíndola Ferreira, Carlos Rodrigues Rocha,
The present work proposes a method to analyze electric energy consumption in manufacturing processes in order to identify potential of reducing this consumption. Computational discrete event modeling/simulation is used as a tool for this analysis, complemented by the use of optimization software, where different scenarios can be explored in order to minimize electricity consumption. A differential of this method is the evaluation of possible solutions as function of indicators in economic, social ...
Tópico(s): Scheduling and Optimization Algorithms
2018 - Elsevier BV | Procedia Manufacturing

Ênio Buffolo, José Carlos Silva de Andrade, João Nelson Rodrigues Branco, Carlos Alberto Teles, Luciano F. Aguiar, Walter J. Gomes,
Coronary artery bypass grafting without cardiopulmonary bypass is now an accepted technique of myocardial revascularization. We herein report our total experience with this procedure.In a consecutive series of 8,751 patients operated on in our institution for coronary artery disease from 1981 to 1994, 1,274 patients received coronary artery bypass grafting without cardiopulmonary bypass.Results indicate that the operation can be performed with an acceptable mortality (2.5%), and that all types of ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
1996 - Elsevier BV | The Annals of Thoracic Surgery
Luís Santos, João Coutinho‐Rodrigues, Carlos Henggeler Antunes,
This article presents a user-friendly web-based spatial decision support system (wSDSS) aimed at generating optimized vehicle routes for multiple vehicle routing problems that involve serving the demand located along arcs of a transportation network. The wSDSS incorporates Google Maps™ (cartography and network data), a database, a heuristic and an ant-colony meta-heuristic developed by the authors to generate routes and detailed individual vehicle route maps. It accommodates realistic system specifics, ...
Tópico(s): Vehicle Routing Optimization Methods
2010 - Elsevier BV | Decision Support Systems
Eduardo Natividade-Jesus, João Coutinho‐Rodrigues, Carlos Henggeler Antunes,
Tópico(s): Transportation Planning and Optimization
2006 - Elsevier BV | Decision Support Systems

João Paulo Rodrigues, Carlos Augusto Fernandes de Oliveira,
In this study, a systematic review is presented on the worldwide occurrence levels of mycotoxins in pastures reported in the scientific literature from January 1987 until December 2021. Trichothecenes and zearalenone were the most frequent mycotoxins found at high levels in pastures from countries in Europe, Oceania, and North America. Alternariol and Ergot alkaloids were also frequently detected, although at low levels. A few surveys were conducted in South American countries, and no information ...
Tópico(s): Plant Pathogens and Fungal Diseases
2022 - Codon Publications | Quality Assurance and Safety of Crops & Foods

Kelly Samara de Lira Mota, João Carlos Lima Rodrigues Pita, Ethiene Castellucci Estevam, Viviane Marcelino Medeiros, Josean Fechine Tavares, Maria de Fátima Agra, Margareth de Fátima Formiga Melo Diniz, Marcelo Sobral da Silva, Leônia Maria Batista,
Maytenus obtusifolia is used in folk medicine for the treatment of serious ulcers, general inflammations and cancer. Despite of the ethnopharmacological importance of this species, no study was conducted to evaluate its toxicity and antiulcerogenic activity. In this study, we evaluated the toxicity and antiulcerogenic property of the ethanol extract of the leaves of Maytenus obtusifolia (MO-EtOH). The MO-EtOH (10-1000 µg/mL) showed low toxicity for larvae of A. salina with LC50 higher than 1000 µg/ ...
Tópico(s): Hedgehog Signaling Pathway Studies
2008 - Springer Science+Business Media | Revista Brasileira de Farmacognosia

Maria F. D. Amorim, Margareth de Fátima Formiga Melo Diniz, Maria Salete Trigueiro de Araújo, João Carlos Lima Rodrigues Pita, Jadson Gomes Dantas, Josué A. Ramalho, Aline Lira Xavier, Thayse V. Palomaro, Nelson L. B. Júnior,
Kava is an anxiolytic herbal medicine used in the treatment of sleep and anxiety disorders. Some cases of kava-induced hepatotoxicity have been reported in the literature leading to its banishment in most countries worldwide. Clinically, the spectrum ranged from transient elevations of liver enzyme levels to fulminant liver failure and death. Liver transplantation was performed in a few cases. This paper provides a review of the currently available literature on kava-related toxic hepatitis which ...
Tópico(s): Complementary and Alternative Medicine Studies
2007 - Springer Science+Business Media | Revista Brasileira de Farmacognosia

João Carlos Lima Rodrigues Pita, Aline Lira Xavier, Tatyanna Kélvia Gomes de Sousa, Vivianne Mendes Mangueira, Josean Fechine Tavares, Robson José de Oliveira Júnior, Robson Cavalcante Veras, Hilzeth de Luna Freire Pessôa, Marcelo Sobral da Silva, Sandra Morelli, Veridiana de Melo Rodrigues, Teresinha Gonçalves da Silva, Margareth de Fátima Formiga Melo Diniz, Marianna Vieira S. Castello-Branco,
Trachylobane-360 (ent-7α-acetoxytrachyloban-18-oic acid) was isolated from Xylopia langsdorffiana. Studies have shown that it has weak cytotoxic activity against tumor and non-tumor cells. This study investigated the in vitro and in vivo antitumor effects of trachylobane-360, as well as its cytotoxicity in mouse erythrocytes. In order to evaluate the in vivo toxicological aspects related to trachylobane-360 administration, hematological, biochemical and histopathological analyses of the treated animals ...
Tópico(s): Alkaloids: synthesis and pharmacology
2012 - Multidisciplinary Digital Publishing Institute | Molecules

Déborah Ribeiro Pessoa Meireles, Heloísa Fernandes, Thaísa Leite Rolim, Tatianne Mota Batista, Vivianne Mendes Mangueira, Tatyanna Kélvia Gomes de Sousa, João Carlos Lima Rodrigues Pita, Aline Lira Xavier, Daiene Martins Beltrão, Josean Fechine Tavares, Marcelo Sobral da Silva, Karina K.P. Medeiros, Marianna Vieira Sobral,
The essential oil from Croton polyandrus Spreng., Euphorbiaceae, leaves was tested for the toxicity and antitumor activity. The concentration producing 50% hemolysis was 141 μg/ml on mice erythrocytes. In the acute toxicological study, the estimated LD50 was 447.18 mg/kg. The essential oil did not induce increase in number of micronucleated erythrocytes, suggesting low genotoxicity. Essential oil (100 or 150 mg/kg) showed significant antitumor activity in Ehrlich ascitic carcinoma model. We observed ...
Tópico(s): Insect Pest Control Strategies
2016 - Springer Science+Business Media | Revista Brasileira de Farmacognosia

Thaísa Leite Rolim, Déborah Ribeiro Pessoa Meireles, Tatianne Mota Batista, Tatyanna Kélvia Gomes de Sousa, Vivianne Mendes Mangueira, Renata Albuquerque de Abrantes, João Carlos Lima Rodrigues Pita, Aline Lira Xavier, Vicente Carlos de Oliveira Costa, Leônia Maria Batista, Marcelo Sobral da Silva, Marianna Vieira Sobral,
The essential oil from Mesosphaerum sidifolium (L'Hérit.) Harley & J.F.B.Pastore (syn. Hyptis umbrosa), Lamiaceae (EOM), and its major component, have been tested for toxicity and antitumor activity.EOM was obtained from aerial parts of M. sidifolium subjected to hydro distillation, and gas chromatography-mass spectrometry was used to characterize the EOM chemical composition. The toxicity was evaluated using haemolysis assay, and acute toxicity and micronucleus tests. Ehrlich ascites carcinoma model ...
Tópico(s): Phytochemistry and Biological Activities
2017 - BioMed Central | BMC Complementary and Alternative Medicine

Valéria Bernadete Leite Quixabeira, João Carlos Nabout, Flávia Melo Rodrigues,
... preparation of this manuscript. Valéria Bernadete Leite Quixabeira*, João Carlos Nabout , Flávia Melo Rodrigues*, * Departamento de Genética, Programa de Mestrado em Genética, ...
Tópico(s): Cancer Genomics and Diagnostics
2009 - Wiley | Cytometry Part A

Ana Sílvia Suassuna Carneiro Lúcio, Jackson Roberto Guedes da Silva Almeida, José Maria Barbosa‐Filho, João Carlos Lima Rodrigues Pita, Marianna Vieira Sobral Castello Branco, Margareth de Fátima Formiga Melo Diniz, Maria de Fátima Agra, Emídio Vasconcelos Leitão da Cunha, Marcelo Sobral da Silva, Josean Fechine Tavares,
Phytochemical investigation of Anaxagorea dolichocarpa Sprague & Sandwith led to isolation of three azaphenanthrene alkaloids: eupolauramine, sampangine and imbiline 1. Their chemical structures were established on the basis of spectroscopic data from IR, HR-ESI-MS, NMR (including 2D experiments) and comparison with the literature. Sampangine and imbiline 1 are being described in the Anaxagorea genus for the first time. Eupolauramine and sampangine show concentration-dependent antitumoral activity ...
Tópico(s): Piperaceae Chemical and Biological Studies
2011 - Multidisciplinary Digital Publishing Institute | Molecules

Ana Paula Gomes Moura, Daiene Martins Beltrão, João Carlos Lima Rodrigues Pita, Aline Lira Xavier, Monalisa Taveira Brito, Tatyanna Kélvia Gomes de Sousa, Leônia Maria Batista, João Ernesto de Carvalho, Ana Lúcia Tasca Góis Ruiz, Adriana Della Torre, Marcelo Cavalcante Duarte, Josean Fechine Tavares, Marcelo Sobral da Silva, Marianna Vieira Sobral,
The genus Xylopia L. (Annonaceae) includes aromatic plants that have both nutritional and medicinal uses. Essential oils of Xylopia species have antitumour effects. However, the efficacy of the essential oil from the fruit of Xylopia langsdorffiana St. Hil & Tul. (EOX) has not been examined.EOX was evaluated to determine its chemical composition, antitumour activity and toxicity.EOX was obtained from fresh fruits of X. langsdorffiana subjected to hydrodistillation, and gas chromatography-mass spectrometry ...
Tópico(s): Plant-derived Lignans Synthesis and Bioactivity
2016 - Taylor & Francis | Pharmaceutical Biology

João Carlos Rodrigues, Alexandre Leme Godoy‐Santos, Marcelo Pires Prado, José Felipe Marion Alloza, Renato Amaral Masagão, Laércio Alberto Rosemberg, Durval do Carmo Barros Santos, Adham do Amaral e Castro, Marco Kawamura Demange, Mário Lenza, Mário Ferretti,
Introduction Although several imaging options are available for diagnosing syndesmotic injury, a fundamental question that guides treatment remains unanswered. Syndesmotic instability is still challenging to diagnose correctly, and syndesmotic disruption and true syndesmotic instability should be differentiated. Currently, imaging tests quickly diagnose severe syndesmotic instability but have difficulty in diagnosing mild and moderate cases. This study aims to investigate which strategy among an ...
Tópico(s): Orthopedic Surgery and Rehabilitation
2020 - BMJ | BMJ Open

Patrícia Moreno Grangeiro, João Carlos Rodrigues, Luiz Renato Agrizzi de Angeli, Hilton Leão Filho, Nei Botter Montenegro, Roberto Guarniero, Molly Dempsey, Harry K.W. Kim,
Background: The etiology of Legg-Calvé-Perthes disease (LCPD) remains unknown; however, interruption of medial circumflex femoral artery (MCFA) supply to the femoral head is the key pathogenic factor. The main purpose of this study is to determine the feasibility of using magnetic resonance angiography (MRA) to evaluate the course of the MCFA in the normal and affected hips of patients with unilateral LCPD. Methods: We analyzed 24 patients with unilateral LCPD using a time-resolved imaging of contrast ...
Tópico(s): Bone and Joint Diseases
2021 - Lippincott Williams & Wilkins | Journal of Pediatric Orthopaedics
Catarina Gomes, Rolando Pinho, Adélia Rodrigues, Ana Ponte, Joana Silva, Jaime Rodrigues, Mafalda Sousa, João Carlos Silva, João Carvalho, Department of Gastroenterology, Centro Hospitalar Vila Nova de Gaia Espinho, Porto, Portugal,
AIMTo evaluate the impact of the timing of capsule endoscopy (CE) in overt-obscure gastrointestinal bleeding (OGIB). METHODSRetrospective, single-center study, including patients submitted to CE in the setting of overt-OGIB between January 2005 and August 2017.Patients were divided into 3 groups according to the timing of CE (≤ 48 h; 48 h-14 d; ≥ 14 d).The diagnostic and therapeutic yield (DY and TY), the rebleeding rate and the time to rebleed were calculated and compared between groups.The outcomes of ...
Tópico(s): Gastrointestinal Tumor Research and Treatment
2018 - Baishideng Publishing Group | World Journal of Gastrointestinal Endoscopy

Izabel Cristina Zattar, João Carlos Espíndola Ferreira, João Gabriel G. G. Rodrigues, Carlos Humberto Barreto de Sousa,
This paper proposes the on-line adaptation of a process plan with alternatives, through the application of an operation-based time-extended negotiation protocol for decision-making for the real-time routing of job orders of parts composed of machining operations in a job-shop environment. The protocol is modified from the contract net protocol, which specifies the interaction between agents in a multi-agent system, in order to cater for the multiple tasks and many-to-many negotiations. A multi-agent ...
Tópico(s): Assembly Line Balancing Optimization
2010 - Taylor & Francis | International Journal of Computer Integrated Manufacturing

Aline Lira Xavier, João Carlos Lima Rodrigues Pita, Monalisa Taveira Brito, Déborah Ribeiro Pessoa Meireles, Josean Fechine Tavares, Marcelo Sobral da Silva, José Guilherme S. Maia, Eloísa Helena de Aguiar Andrade, Margareth de Fátima Formiga Melo Diniz, Teresinha Gonçalves da Silva, H. L. F. Pessôa, Marianna Vieira Sobral,
Abstract The chemical composition, antitumor activity and toxicity of the essential oil from Lippia microphylla leaves (OEL) were investigated. The major constituents were thymol (46.5%), carvacrol (31.7%), p -cymene (9%), and γ-terpinene (2.9%). To evaluate the toxicity of OEL in non-tumor cells, the hemolytic assay with Swiss mice erythrocytes was performed. The concentration producing 50% hemolysis (HC 50 ) was 300 μg/mL. Sarcoma 180 tumor growth was inhibited in vivo 38% at 50 mg/kg, and 60% at 100 mg/ ...
Tópico(s): Plant chemical constituents analysis
2015 - De Gruyter | Zeitschrift für Naturforschung C

Walter J. Gomes, Isadora S. Rocco, Wallace S. Pimentel, Aislan Henrique Bezerra Pinheiro, Paulo M. S. Souza, Luiz A. A. Costa, Marjory M. P. Teixeira, Leonardo Paiva Ohashi, Caroline Bublitz, Isis Begot, Rita Simone Lopes Moreira, Nelson Américo Hossne, Guilherme F. Vargas, João Nelson Rodrigues Branco, Carlos Teles, Eduardo Alexandrino Medeiros, Camila Sáfadi, Amândio Rampinelli, Leopoldo Moratelli Neto, Anderson Rosa Rosado, Franciele Kuhn Mesacasa, Ismael Escobar Capriata, Rodrigo Coelho Segalote, Deborah Louize da Rocha Vianna Palmieri, Amanda Cristina Mendes Jardim, Diego Sarty Vianna, Joaquim Henrique de Souza Aguiar Coutinho, João Carlos Jazbik, Henrique Madureira da Rocha Coutinho, Gustavo Kikuta, Zely Sant’Anna Marotti de Almeida, Gibran Roder Feguri, Paulo Ruiz Lúcio de Lima, A. Franco, Danilo de Cerqueira Borges, Felipe Ramos Honorato De La Cruz, Ulisses Alexandre Croti, Bruna Cury Borim, Carlos Henrique De Marchi, Lílian Goraieb, Karolyne Barroca Sanches Postigo, Fabiano Gonçalves Jucá, Fátima Rosane de Almeida Oliveira, Rafael Bezerra de Souza, Alexandre Cabral Zilli, Raul Gaston Sanchez Mas, Luiz Carlos Bettiati, Ricardo Tranchesi, Ayrton Bertini, Leandro Vieira Franco, Priscila Valente Fernandes, Fabiana Sodré de Oliveira, Roberto Alexandre Vitória de Moraes, Thiago Cavalcanti Vila Nova de Araújo, Otávio Penna Braga, Antônio Cavalcanti Pedrosa Sobrinho, Roberta Tavares Barreto Teixeira, Irla Lavor Lucena Camboim, Eduardo Nascimento Gomes, Pedro Horigushi Reis, Luara Piovan Garcia, Nelson Henrique Goes Scorsioni, R Dal Lago, Solange Guizilini,
We investigated the clinical course and outcomes of patients submitted to cardiovascular surgery in Brazil and who had developed symptoms/signs of coronavirus disease 2019 (COVID-19) in the perioperative period.A retrospective multicenter study including 104 patients who were allocated in three groups according to time of positive real time reverse transcriptase-polymerase chain reaction (RT-PCR) for the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2): group 1, patients who underwent cardiac ...
Tópico(s): Cardiac Arrest and Resuscitation
2021 - Brazilian Society of Cardiovascular Surgery | Brazilian Journal of Cardiovascular Surgery

Sergio Yesid Gómez González, Óscar Álvarez, Jairo Arturo Escobar, João Batista Rodrigues Neto, Carlos R. Rambo, Dachamir Hotza,
Using rheological parameters of ceramic suspensions, it is possible to taylor the structure of the ceramic foams produced by replica. This method consists in the impregnation of a polymeric flexible template (polyurethane foam) with a ceramic suspension (slurry) containing the appropriate additives, followed by burning out organic compounds and additives and sintering the ceramic structure. In this work, ceramic foams were produced by the replica method from Al 2 O 3 and 3% Y 2 O 3 -ZrO 2 . Rheological ...
Tópico(s): Injection Molding Process and Properties
2012 - Hindawi Publishing Corporation | Advances in Materials Science and Engineering

Andréa Carvalho da Silva, Sarita Leonel, Adilson Pacheco de Souza, João Rodrigues Domingos, Carlos Ducatti,
No presente trabalho, determinaram-se as trocas gasosas de folhas de figueira 'Roxo de valinhos' e o ciclo fotossintético por meio da relação isotópica 12C/13C. Essas medidas foram realizadas sempre na região mediana das folhas, completamente expandidas e totalmente expostas à radiação solar, no período das 09h00min às 10h30min. As folhas fotossinteticamente ativas da figueira apresentaram área foliar em torno de 160cm², com uma assimilação de 14,38µmol m-2 s-1 de CO2, cujos valores isotópicos médios ...
Tópico(s): Plant Physiology and Cultivation Studies
2010 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural

Marcelo Andreotti, João Domingos Rodrigues, Carlos Alexandre Costa Crusciol, Euclides Caxambu Alexandrino de Souza, Leonardo Theodoro Büll,
Os teores de Ca, Mg e K no solo interferem no crescimento e na produção das culturas. No entanto, a relação entre esses nutrientes que proporciona o desenvolvimento adequado das plantas varia entre as espécies vegetais. O presente teve por objetivo estudar o desenvolvimento do milho em função da saturação do solo por bases e adubação potássica. O delineamento experimental foi inteiramente casualizado, com quatro repetições, em esquema fatorial 3x2x4, constituindo-se de três solos (Neossolo Quartzarênico, ...
Tópico(s): Crop Yield and Soil Fertility
2001 - UNIVERSIDADE DE SÃO PAULO | Scientia Agricola

Monalisa Taveira Brito, Rafael Carlos Ferreira, Daiene Martins Beltrão, Ana Paula Gomes Moura, Aline Lira Xavier, João Carlos Lima Rodrigues Pita, Tatianne Mota Batista, Giovanna Barbarini Longato, Ana Lúcia Tasca Góis Ruiz, João Ernesto de Carvalho, Karina Carla de Paula Medeiros, Sócrates Golzio dos Santos, Vicente Carlos de Oliveira Costa, Josean Fechine Tavares, Margareth de Fátima Formiga Melo Diniz, Marianna Vieira Sobral,
Annona leptopetala (R.E.Fr.) H. Rainer, Annonaceae, is used in folk medicine like antitumor and anti-inflammatory. The aim of this study was to determine chemical composition, toxicity and antitumor activity of A. leptopetala leaves volatile oil. Fresh leaves were hydrodistilled and then the volatile oil chemical composition was assessed by gas chromatography and mass spectrometry. Toxicity was assessed using haemolysis, micronucleus and acute toxicity protocols. Antitumor effects were determined ...
Tópico(s): Piperaceae Chemical and Biological Studies
2018 - Springer Science+Business Media | Revista Brasileira de Farmacognosia

André Rösch Rodrigues, João Carlos Cattini Maluf, Elisabete de Santis Braga, Beatriz Beck Eichler,
Abstract This investigation attempts to determine which environmental parameters of the bottom water and sediment control recent foraminifera fauna at Ezcurra Inlet (King George Island, Antarctica), using data collected during four summers (2002/03, 2003/04, 2004/05 and 2006/07). The study revealed that Ezcurra Inlet contain typical Antarctic foraminifera fauna with three distinct assemblages and few differences in environmental parameters. The species Bolivina pseudopunctata , Fursenkoina fusiformis , ...
Tópico(s): Geology and Paleoclimatology Research
2010 - Cambridge University Press | Antarctic Science