João Correia, Ana Isabel Louro Ponte, João Carlos Silva, Catarina Gomes, Edgar Afecto,
Correia, João P.; Ponte, Ana I.; Silva, João C.; Gomes, Ana C.; Afecto, Edgar Author Information
Tópico(s): Gastrointestinal disorders and treatments
2021 - Lippincott Williams & Wilkins | European Journal of Gastroenterology & Hepatology
António Ferrer Correia, João Paiva, Victor M. S. Gil,
... TO ISSUEPREVArticleLe Chat: Simulation in Chemical EquilibriumAntónio Ferrer Correia , João C. M. Paiva , and Victor M. S. Gil ...
Tópico(s): Molecular Junctions and Nanostructures
2002 - American Chemical Society | Journal of Chemical Education
Catarina Eloy, Ana Marques, João Correia Pinto, Jorge Pinheiro, Sofia Campelos, Mónica Curado, João Vale, António Polónia,
Paige Prostate is a clinical-grade artificial intelligence tool designed to assist the pathologist in detecting, grading, and quantifying prostate cancer. In this work, a cohort of 105 prostate core needle biopsies (CNBs) was evaluated through digital pathology. Then, we compared the diagnostic performance of four pathologists diagnosing prostatic CNB unaided and, in a second phase, assisted by Paige Prostate. In phase 1, pathologists had a diagnostic accuracy for prostate cancer of 95.00%, maintaining ...
Tópico(s): Genital Health and Disease
2023 - Springer Science+Business Media | Virchows Archiv
João Correia, Anabela Borges, Manuel Simões, Lúcia C. Simões,
Antibiotics are a staple in current medicine for the therapy of infectious diseases. However, their extensive use and misuse, combined with the high adaptability of bacteria, has dangerously increased the incidence of multi-drug-resistant (MDR) bacteria. This makes the treatment of infections challenging, especially when MDR bacteria form biofilms. The most recent antibiotics entering the market have very similar modes of action to the existing ones, so bacteria rapidly catch up to those as well. ...
Tópico(s): Fungal Biology and Applications
2023 - Multidisciplinary Digital Publishing Institute | Antibiotics
... 10.1111/j.1465-7295.1996.tb01367.xIsabel Correia, João C. Neves, Sergio Rebelo Business cycles in a ...
Tópico(s): Fiscal Policy and Economic Growth
1985 - University of Chicago Press | Journal of Political Economy
... https://doi.org/10.2139/ssrn.2374956Fernando Motta Correia, João Basílio Pereima, Curva de Phillips e macrodinâmica do ...
Tópico(s): Economic, financial, and policy analysis
1972 - University of Chicago Press | Journal of Political Economy
María Manuela Estevinho, Rolando Pinho, Carlos Fernandes, Adélia Rodrigues, Ana Ponte, Catarina Gomes, Edgar Afecto, João Correia, João Carvalho,
Tópico(s): Gastrointestinal Tumor Research and Treatment
2021 - Elsevier BV | Gastrointestinal Endoscopy
Mateus Hofmann, Abu T. Shahid, Mário Garrido, M.J. Ferreira, João R. Correia, João C. Bordado,
Reducing the dependency from petroleum-based monomers and crosslinkers is an increasingly important goal for the plastics industry. This is being enabled by the growing diversity and availability of alternative biobased products derived from renewable resources, some of which are compatible with the production of more sustainable resins for high-performance applications. This paper presents the development of unsaturated polyesters (UPs) and their crosslinked resins (UPRs) based on 2,5-furandicarboxylic ...
Tópico(s): Lignin and Wood Chemistry
2022 - American Chemical Society | ACS Sustainable Chemistry & Engineering
João M. Sousa, João R. Correia, João P. Firmo, S. Cabral‐Fonseca, José Gonilha,
This paper presents experimental and numerical investigations about the effects of thermal cycles on adhesively bonded joints between pultruded glass fibre reinforced polymer – unsaturated polyester (GFRP) adherends used in civil engineering structural applications. Single lap bonded joints were produced with two commercial polymeric adhesives – epoxy (EP) and polyurethane (PUR) – and exposed to a mild (Mediterranean) range of thermal variations (−5 °C–40 °C) for up to 350 cycles in a dry condition. The mechanical ...
Tópico(s): Structural Load-Bearing Analysis
2018 - Elsevier BV | Composite Structures
S. Cabral‐Fonseca, João R. Correia, João Custódio, Huana Mônica Primo Cardoso Da Silva, A. Machado, João M. Sousa,
Fibre Reinforced Polymer (FRP) composites have been the source of an increasing interest in the field of rehabilitation, namely for repair and strengthening of reinforced concrete (RC) structures. One of the most effective techniques comprises externally bonded FRP composites, in which the efficacy of rehabilitation depends considerably on the integrity and durability of the bond established between the FRP and the substrate, which is provided by a structural adhesive. This paper presents a concise ...
Tópico(s): Innovative concrete reinforcement materials
2018 - Elsevier BV | International Journal of Adhesion and Adhesives
Inês C. Rosa, Tânia Morgado, João R. Correia, João P. Firmo, Nuno Silvestre,
The use of fiber-reinforced polymer (FRP) materials is becoming commonplace in various civil engineering applications due to the several advantages they offer over traditional materials. However, the limited knowledge about some aspects of the behavior of these materials, particularly when subjected to elevated temperatures, is hampering their widespread use. This paper presents experimental and analytical investigations about the shear behavior of pultruded glass fiber-reinforced polymer (GFRP) profiles ...
Tópico(s): Innovative concrete reinforcement materials
2018 - American Society of Civil Engineers | Journal of Composites for Construction
P. Duarte, João R. Correia, João Gomes Ferreira, Francisco Nunes, M.R.T. Arruda,
This paper presents experimental and numerical investigations on the effect of repairing cracks in reinforced concrete (RC) beams prior to strengthening them with carbon fibre reinforced polymer (CFRP) laminates. The experimental campaign comprised flexural tests on three types of full-scale RC beams with T-shaped cross-section: (i) two reference un-strengthened beams, (ii) two CFRP-strengthened beams previously loaded and cracked, and (iii) two CFRP-strengthened beams, previously loaded, cracked and ...
Tópico(s): Innovative concrete reinforcement materials
2014 - NRC Research Press | Canadian Journal of Civil Engineering
Francisco Nunes, Miguel Correia, João R. Correia, Nuno Silvestre, A.L.N. Moreira,
Glass fiber reinforced polymer (GFRP) pultruded profiles are being increasingly used in civil engineering applications. Although they offer several advantages over traditional materials, such as high strength, lightness and non-corrodibility, GFRP profiles present low elasticity and shear moduli, which together with their slender walls makes them very prone to buckling phenomena. Several previous studies addressed the global and local buckling behavior of GFRP pultruded members under concentric loading. ...
Tópico(s): Composite Structure Analysis and Optimization
2013 - Elsevier BV | Thin-Walled Structures
João R. Correia, João Gomes Ferreira, Fernando A. Branco,
Abstract Glass fibre-reinforced concrete (GRC) has been used for more than 30 years in the construction industry, especially in facade panels. In this paper, a rehabilitation case study is presented, of a building where cracking and excessive deformations were detected in the sandwich GRC facade panels due to thermal effects. The structural behaviour of the panels was simulated with a finite element method (FEM) model, validated by experimental tests performed on the facade, and then used to assess ...
Tópico(s): Innovations in Concrete and Construction Materials
2005 - Elsevier BV | Construction and Building Materials
María Manuela Estevinho, Carlos Fernandes, João Carlos Silva, Catarina Gomes, Edgar Afecto, João Correia, João Carvalho,
Background: Molecular therapy with sorafenib remains the mainstay for advancedstage hepatocellular carcinoma. Notwithstanding, treatment efficacy is low, with few patients obtaining long-lasting benefits due to the high chemoresistance rate. Objective: To perform, for the first time, an overview of the literature concerning the role of adenosine triphosphate-binding cassette (ABC) transporters in sorafenib therapy for hepatocellular carcinoma. Methods: Three online databases (PubMed, Web of Science, ...
Tópico(s): HIV/AIDS drug development and treatment
2021 - Bentham Science Publishers | Current Drug Targets
Júlia Santos, Fernanda Leitão-Correia, Maria João Sousa, Cecı́lia Leão,
// Júlia Santos 1,2 , Fernanda Leitão-Correia 3 , Maria João Sousa 3,* and Cecília Leão 1,2,* 1 Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, ...
Tópico(s): Genetic Neurodegenerative Diseases
2014 - Impact Journals LLC | Oncotarget
Andreia F. Carvalho, João Costa‐Rodrigues, Isabel Correia, João Costa Pessoa, Tiago Q. Faria, M. Cristina L. Martins, Marc Fransen, Clara Sá-Miranda, Jorge E. Azevedo,
Targeting of most newly synthesised peroxisomal matrix proteins to the organelle requires Pex5p, the so-called PTS1 receptor. According to current models of peroxisomal biogenesis, Pex5p interacts with these proteins in the cytosol, transports them to the peroxisomal membrane and catalyses their translocation across the membrane. Presently, our knowledge on the structural details behind the interaction of Pex5p with the cargo proteins is reasonably complete. In contrast, information regarding the ...
Tópico(s): Signaling Pathways in Disease
2005 - Elsevier BV | Journal of Molecular Biology
Cristina Jácome, Ana Margarida Pereira, Rute Almeida, Manuel Ferreira‐Magalhães, Mariana Couto, Luís Araújo, Mariana Pereira, Magna Alves‐Correia, Cláudia Chaves Loureiro, Maria Joana Catarata, Lília Maia Santos, João Gonçalves-Pereira, Bárbara Ramos, Cristina Lopes, Ana Mendes, José Carlos Cidrais Rodrigues, Georgeta Oliveira, Ana Paula Aguiar, Ivete Afonso, Joana Carvalho, Ana Arrobas, José Coutinho Costa, Joana Alves Dias, Ana Todo‐Bom, João Azevedo, Carmelita Ribeiro, Marta Alves, Paula Pinto, Nuno Neuparth, Ana Palhinha, João Gaspar Marques, Nicole Pinto, Pedro Martins, Filipa Todo Bom, Maria Alvarenga Santos, Alberto Costa, Armandina Silva Neto, Marta Santalha, Carlos Lozoya, Natacha Santos, Diana Silva, Maria João Vasconcelos, Luís Taborda‐Barata, Célia Carvalhal, Maria Fernanda Teixeira, Rodrigo Rodrigues Alves, Ana Sofia Moreira, Cláudia Sofia Pinto, Pedro Morais Silva, Carlos Alves, Raquel Câmara, Didina Coelho, Diana Bordalo, Ricardo M. Fernandes, Rosário Ferreira, Fernando Menezes, Ricardo Gomes, Maria José Cálix, Ana Marques, João Cardoso, Madalena Emiliano, Rita Gerardo, Carlos Nunes, Rita Câmara, José Alberto Ferreira, Aurora Carvalho, Paulo Freitas, Ricardo Cruz‐Correia, João Fonseca,
We aimed to compare patient's and physician's ratings of inhaled medication adherence and to identify predictors of patient-physician discordance.Baseline data from two prospective multicentre observational studies.29 allergy, pulmonology and paediatric secondary care outpatient clinics in Portugal.395 patients (≥13 years old) with persistent asthma.Data on demographics, patient-physician relationship, upper airway control, asthma control, asthma treatment, forced expiratory volume in one second (FEV1) ...
Tópico(s): Cystic Fibrosis Research Advances
2019 - BMJ | BMJ Open
Ana Paula Soares Dias, Jaime Puna, João Gomes, M. Joana Neiva Correia, João C. Bordado,
Lime is pointed out as an effective catalyst for biodiesel production by oil methanolysis. Several Ca phases are formed during reaction. Each Ca phase has different contribution to the catalyzed process. Using CaO as a catalyst, S shape kinetics curve was observed and the induction period can be ascribed to the Ca(OH)2 formation. When Ca(OH)2, prepared by contacting CaO with H2O, is used as catalyst the initial period with a slow rate of transesterification has almost vanished. Besides, if the catalyst ...
Tópico(s): Catalysis and Hydrodesulfurization Studies
2016 - Elsevier BV | Renewable Energy
Diogo de Sousa, João Patrocínio, Joana Frade, Catarina Correia, João Borges‐Costa, Paulo Filipe,
Human monkeypox (MPX) is a zoonotic endemic disease in regions of Africa caused by the monkeypox virus, with a recent outbreak in several non-African countries. We report a case of a 24-year-old male patient with a concurrent diagnosis of MPX and acute HIV infection who presented to our Emergency Care Dermatology Clinic with disseminated papules throughout the trunk, face and genital area. On the perianal area, several grouped umbilicated whitish papules in a kissing lesion configuration could be ...
Tópico(s): Bacillus and Francisella bacterial research
2022 - SAGE Publishing | International Journal of STD & AIDS
Júlia Santos, Fernanda Leitão-Correia, Maria João Sousa, Cecı́lia Leão,
// Júlia Santos 1,2 , Fernanda Leitão-Correia 3 , Maria João Sousa 3,* and Cecília Leão 1,2,* 1 Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, ...
Tópico(s): Muscle Physiology and Disorders
2016 - Impact Journals LLC | Oncotarget
Pedro Felizardo, João Machado, Daniel Vergueiro, M. Joana Neiva Correia, João Gomes, João C. Bordado,
Biodiesel is the main alternative to fossil diesel and it may be produced from different feedstocks such as semi-refined vegetable oils, waste frying oils or animal fats. However, these feedstocks usually contain significant amounts of free fatty acids (FFA) that make them inadequate for the direct base catalyzed transesterification reaction (where the FFA content should be lower than 4%). The present work describes a possible method for the pre-treatment of oils with a high content of FFA (20 to 50%) ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2011 - Elsevier BV | Fuel Processing Technology
Guilherme dos Alexandre Santos Espadanal Ramos, João R. Vaz, Gonçalo V. Mendonça, Pedro Pezarat–Correia, João Rodrigues, Miquel Alfaras, Hugo Gambôa,
Research in physiology and sports science has shown that fatigue, a complex psychophysiological phenomenon, has a relevant impact in performance and in the correct functioning of our motricity system, potentially being a cause of damage to the human organism. Fatigue can be seen as a subjective or objective phenomenon. Subjective fatigue corresponds to a mental and cognitive event, while fatigue referred as objective is a physical phenomenon. Despite the fact that subjective fatigue is often undervalued, ...
Tópico(s): Vehicle Noise and Vibration Control
2020 - Hindawi Publishing Corporation | Journal of Healthcare Engineering
Ana Inês Martins, João Sargento‐Freitas, Fernando Silva, Joana Jesus‐Ribeiro, Inês Correia, João Pedro Gomes, Mariana Aguiar-Gonçalves, Leila Cardoso, Cristina Machado, Bruno Rodrigues, Gustavo Cordeiro, Luı́s Cunha,
Historical stroke cohorts reported a U- or J-shaped relationship between blood pressure (BP) and clinical outcome. However, these studies predated current revascularization strategies, disregarding the recanalization state of the affected arterial territory. We aimed to investigate the relationship between BP in the first 24 hours after ischemic stroke and clinical outcome in patients submitted to intravenous or intra-arterial recanalization treatments.Consecutive patients with acute stroke treated ...
Tópico(s): Traumatic Brain Injury and Neurovascular Disturbances
2016 - Lippincott Williams & Wilkins | Stroke
Diogo de Sousa, João Patrocínio, Joana Frade, Cláudia Brazão, Dora Mancha, Catarina Correia, João Borges‐Costa, Paulo Filipe,
A monkeypox outbreak has been reported in several countries since early May 2022. Human monkeypox (MPX) diagnosis is based on a clinical suspicion supported by typical skin and mucosal lesions, confirmed with molecular testing. We present the results of all MPX confirmed patients presenting to our department until July 15 of 2022, describing the characteristics of the lesions at diagnosis. In total, 47 patients were included, all men and 44.7% (n = 21) were HIV-positive. Skin lesions were noted in all ...
Tópico(s): Bacillus and Francisella bacterial research
2022 - Multidisciplinary Digital Publishing Institute | Infectious Disease Reports
Gonçalo N. P. Oliveira, André M. Pereira, A. M. L. Lopes, João S. Amaral, António M. dos Santos, Yang Ren, Teresa Mendonça, C. T. Sousa, V. S. Amaral, J. G. Correia, João P. Araújo,
The cubic spinel CdCr${}_{2}$S${}_{4}$ gained recently a vivid interest, given the relevance of relaxor-like dielectric behavior in its paramagnetic phase. By a singular combination of local probe techniques, namely, pair distribution function and perturbed angular correlation, we firmly establish that the Cr ion plays the central key role on this exotic phenomenon, namely, through a dynamic off-centering displacement of its coordination sphere. We further show that this off-centering of the magnetic ...
Tópico(s): Magnetic and transport properties of perovskites and related materials
2012 - American Physical Society | Physical Review B
Jafar Jafari‐Asl, Mohamed El Amine Ben Seghier, Sima Ohadi, José A.F.O. Correia, João Barroso,
In this paper, a new framework for accurate reliability analysis is proposed based on improving the directional simulation by using metaheuristic algorithms. Usually for highly nonlinear and complex performance functions, finding the unit vector direction requires very high calculations or impossible practically. Hence, the novel improved version incorporates the Harris Hawks Optimization algorithm, where the unit vector of direction is formulated as a constrained optimization problem and estimated ...
Tópico(s): Reliability and Maintenance Optimization
2022 - Elsevier BV | Engineering Failure Analysis
Renato Oliveira, Manuel Correia, João Pedro Marto, Mariana Carvalho Dias, Ghada Mohamed, Thanh N. Nguyen, Raul G. Nogueira, Hassan Aboul Nour, Horia Marin, Alex Chebl, Mahmoud Mohammaden, Alhamza R Al‐Bayati, Diogo C Haussen, Mohamad Abdalkader, Johanna T Fifi, Santiago Ortega‐Gutiérrez, Dileep R. Yavagal, Stephan A. Mayer, Georgios Tsivgoulis, Lia Lucas Neto, Diana Aguiar de Sousa,
Endovascular treatment (EVT) is the standard of care for selected patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO).To systematically review the available data on: (1) incidence, predictors, and outcomes of patients with reocclusion after successful EVT for AIS and, (2) the characteristics, complications, and outcomes of patients with reocclusion treated with repeated EVT (rEVT) within 30 days of the first procedure.PubMed was searched (between January 2012 and April 2021) to ...
Tópico(s): Stroke Rehabilitation and Recovery
2022 - BMJ | Journal of NeuroInterventional Surgery
Catarina Nascimento, Andreia Gameiro, Jorge Correia, João Ferreira, Fernando Ferreira,
Feline mammary carcinoma (FMC) shares key molecular and clinicopathological features with human breast cancer. We have herein studied the inflammatory infiltrate of FMC in order to uncover potential therapeutic targets and prognostic markers. To this end, the expression of different markers (CD3, CD4, CD8, CD20, CD56, FoxP3, CD68 and CD163) was analyzed in total, stromal (s) and intratumoral (i) tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs), in 73 feline mammary carcinomas. ...
Tópico(s): Cancer Cells and Metastasis
2022 - Multidisciplinary Digital Publishing Institute | Cells
Sara Nadine, Inês Fernandes, Clara R. Correia, João F. Mano,
In order to solve the clinical challenges related to bone grafting, several tissue engineering (TE) strategies have been proposed to repair critical-sized defects.Generally, the classical TE approaches are designed to promote bone repair via intramembranous ossification (IMO).Although promising, strategies that direct the osteogenic differentiation of mesenchymal stem/stromal cells are usually characterized by a lack of functional vascular supply, often resulting in necrotic cores and subsequent failure ...
Tópico(s): Bone Tissue Engineering Materials
2022 - Cell Press | iScience