Jonas S. Almeida, Chuming Chen, Robert Gorlitsky, Romesh Stanislaus, Marta Aires-de-Sousa, Pedro Eleutério, João André Carriço, António Maretzek, Andreas Böhn, Allen Y. Chang, Fan Zhang, Rahul Mitra, Gordon B. Mills, Xiaoshu Wang, Helena Deus,
Tópico(s): Scientific Computing and Data Management
2006 - Nature Portfolio | Nature Biotechnology
Produção Nacional
Eanes Torres Pereira, Sidney Pimentel Eleutério, João Marques Carvalho,
Among all cancer types, breast cancer is the one with the second highest incidence rate for women. Mammography is the most used method for breast cancer detection, as it reveals abnormalities such as masses, calcifications, asymmetries and architectural distortions. In this paper, we propose a classification method for breast cancer that has been tested for six different cancer types: CALC, CIRC, SPIC, MISC, ARCH, ASYM. The proposed approach is composed of a SVM classifier trained with LBP features. ...
Tópico(s): Gene expression and cancer classification
2014 - | Revista de Informática Teórica e Aplicada
Produção Nacional
Revisado por pares
João Marcus Oliveira Andrade, Alanna Fernandes Paraíso, Marcos Vinícius Macêdo de Oliveira, Andreá Maria Eleutério de Barros Lima Martins, João Felício Rodrigues Neto, André Luiz Sena Guimarães, Alfredo Maurício de Paula, Mahboob Qureshi, Sérgio Henrique Sousa Santos,
Resveratrol (RSV) is the most studied natural compound that activates sirtuins, which produce beneficial metabolic effects on lipid and glucose metabolism. The aim of the present study was to investigate the role of resveratrol in preventing nonalcoholic fatty liver disease (NAFLD) and expression of liver inflammatory markers in mice treated with a high-fat diet.Eighteen male mice were divided into three groups and fed for 60 d with a standard diet (ST), high-fat diet (HFD), or high-fat diet plus resveratrol ( ...
Tópico(s): Adipose Tissue and Metabolism
2013 - Elsevier BV | Nutrition
Produção Nacional
Amanda Ferraz Pêgo, Dayna Eleutério, João Paulo Martins Procópio, Victor Augusto Santos Condé, Eduardo Gonçalves,
Objetivo: Traçar o perfil epidemiológico dos casos de Hanseníase visando correlacionar o número de lesões hansênicas, os nervos afetados e o diagnóstico precoce da doença. Métodos: Estudo transversal, descritivo e quantitativo. Consultaram-se informações disponíveis sobre Hanseníase no Sistema de Informações de Agravos de Notificação (SINAN), relativas ao período entre 2014 e 2018. As variáveis do estudo foram divididas em número de notificações da doença, relacionadas ao: sexo, faixa etária, forma ...
Tópico(s): Yersinia bacterium, plague, ectoparasites research
2020 - Revista Eletronica Acervo Saude | Revista Eletrônica Acervo Saúde
Produção Nacional
Revisado por pares
Andreá Maria Eleutério de Barros Lima Martins, Kimberly Marie Jones, João Gabriel Silva Souza, Isabela Almeida Pordeus,
Objetivou-se avaliar a associação entre o impacto das desordens bucais em suas dimensões física/psicossocial e a qualidade de vida entre idosos. Estudo transversal conduzido entre idosos (65-74 anos), em 2008/2009. O impacto foi avaliado através do Oral Health Impact Profile (OHIP 14) e a qualidade de vida, através do Short-Form Health Survey SF 12. Foram realizadas análises descritivas, univariadas e múltiplas (regressões logísticas), com correção pelo efeito de desenho, utilizando-se o PASW(r) 18. ...
Tópico(s): Health Education and Validation
2014 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
Andreá Maria Eleutério de Barros Lima Martins, Lorena Amaral Jardim, João Gabriel Silva Souza, Carlos Alberto Quintão Rodrigues, Raquel Conceição Ferreira, Isabela Almeida Pordeus,
This study aimed at identifying the prevalence of the negative evaluation of dental services among elderly Brazilians and at investigating whether the prevalence was higher among those using public or philanthropic provider services than among those paying privately or using private health plans. Additionally, factors associated with this negative assessment were identified. Interview and survey data were collected in the residences of participants by trained and calibrated examiners as part of ...
Tópico(s): Dental Health and Care Utilization
2014 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Revista Brasileira de Epidemiologia
Produção Nacional
Revisado por pares
Andreá Maria Eleutério de Barros Lima Martins, Jairo Evangelista Nascimento, João Gabriel Silva Souza, Maria Aparecida Barbosa de Sá, Sara de Barros Lima Feres, Bruno Porto Soares, Efigênia Ferreira e Ferreira,
The scope of this study was to evaluate the association between the presence of common mental disorders and the impairment of subjective health conditions among the elderly. It involved a cross-sectional analytical survey conducted among all the elderly residents in the urban area of a Brazilian municipality with low population density. Mental disorders were evaluated using the short version of the Goldberg General Health questionnaire. Subjective and normative health conditions were evaluated and ...
Tópico(s): Occupational Health and Burnout
2016 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
Andreá Maria Eleutério de Barros Lima Martins, Sandhi Maria Barreto, Pedro Eleutério dos Santos-Neto, Maria Aparecida Barbosa de Sá, João Gabriel Silva Souza, Desirée Sant’Ana Haikal, Efigênia Ferreira e Ferreira, Isabela Almeida Pordeus,
Resumo Na promoção de saúde, as ações educativas são prioridade na Estratégia de Saúde da Família (ESF). Evidencia-se a eficácia dessas ações na adesão a comportamentos saudáveis e na redução nas taxas de morbimortalidade por câncer bucal. Objetivou-se identificar se o acesso a informações sobre como prevenir o câncer bucal é maior entre idosos residentes em domicílios cadastrados na ESF. Utilizou-se o SPSS® na obtenção de estimativas corrigidas pelo efeito do desenho amostral, considerando as magnitudes ...
Tópico(s): Maternal and Neonatal Healthcare
2015 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
Andreá Maria Eleutério de Barros Lima Martins, Raquel Conceição Ferreira, Pedro Eleutério dos Santos Neto, Danilo Lima Carreiro, João Gabriel Silva Souza, Efigênia Ferreira e Ferreira,
OBJECTIVE To examine whether demographic, socioeconomic conditions, oral health subjectivity and characterization of dental care are associated with users’ dissatisfaction with such are. METHODS Cross-sectional study of 781 people who required dental care in Montes Claros, MG, Southeastern Brazil, in 2012, a city with of medium-sized population situated in the North of Minas Gerais. Household interviews were conducted to assess the users’ dissatisfaction with dental care (dependent variable), demographic, ...
Tópico(s): Dental Anxiety and Anesthesia Techniques
2015 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Produção Nacional
Revisado por pares
Andreá Maria Eleutério de Barros Lima Martins, João Gabriel Silva Souza, Desirée Sant’Ana Haikal, Alfredo Maurício Batista de Paula, Efigênia Ferreira e Ferreira, Isabela Almeida Pordeus,
The aim of this study was to examine the prevalence of oral cancer self-examinationamong the elderly and confirm whether prevalence was higher among users of the dental services provided by Brazil's Unified Health System (SUS, acronym in Portuguese). A transversal study of elderly people aged between 65 and 74 years living in a large-sized Brazilian municipality was conducted using simple random sampling. Logistic regression was conducted and results were corrected for sample design and unequal weighting ...
Tópico(s): Oral health in cancer treatment
2015 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Manuela Carvalheiro, Joáo C. S. Jorge, Carla Eleutério, Ana F. Pinhal, Ana Carolina Corrêa de Sousa, José Morais, M.E.M. Cruz,
The purpose of this study was to increase the therapeutic index of the antiparasitic drug, trifluralin (TFL), to allow its parenteral administration without the need of toxic solvents. This was achieved by incorporating TFL in liposomes with high loading capacity. These formulations were stable in freeze-dried form during at least one year and in frozen form during at least three months. Therapeutic activity, assessed on a visceral model of infection, showed that TFL liposomes reduced the number ...
Tópico(s): Trypanosoma species research and implications
2008 - Elsevier BV | European Journal of Pharmaceutics and Biopharmaceutics
Produção Nacional
Revisado por pares
Laíse Angélica Mendes Rodrigues, Andreá Maria Eleutério de Barros Lima Martins, Marise Fagundes Silveira, Raquel Conceição Ferreira, João Gabriel Silva Souza, José António Raimundo Mendes da Silva, Antônio Prates Caldeira,
The prevalence and factors associated with the use of dental services in a representative, probabilistic, complex sample with two-stage clusters of preschoolers aged 18 to 36 months was estimated. Structured questionnaires were answered by parents/guardians and the preschoolers were assessed by trained and qualified dental surgeons. In the analysis the corrections for the design effect were considered and the magnitudes of the associations based on logistic regression (OR/IC 95%) were estimated. ...
Tópico(s): Global Maternal and Child Health
2014 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
João Gabriel Silva Souza, Andreá Maria Eleutério de Barros Lima Martins, Marise Fagundes Silveira, Kimberly Marie Jones, Maria Paula Maciel Rando Meirelles,
Background Oral health‐related quality of life may be influenced by a series of characteristics. Considering the multidimensional character of quality of life, these impacts should be evaluated in the context of the physical, psychological, and social domains. Aim To evaluate the impact of clinical and perceived oral health problems on oral health‐related quality of life in its different domains. Design Clinical exams were conducted on a representative cross‐sectional sample of 12‐year‐old children ...
Tópico(s): Maternal and Neonatal Healthcare
2016 - Wiley | International Journal of Paediatric Dentistry
Produção Nacional
Raquel Conceição Ferreira, Alessandra Pastore da Silveira, Maria Aparecida Barbosa de Sá, Sara de Barros Lima Feres, João Gabriel Silva Souza, Andreá Maria Eleutério de Barros Lima Martins,
ResumoOs professores universitários estão expostos a um aumento de tensão no trabalho pela fragmentação da sua atividade e as responsabilidades exigidas, sem que, em muitas situações, tenham as condições necessárias para responder adequadamente. Tal situação pode representar condições estressoras, aumentando o risco de transtornos mentais. Investigou-se a associação entre transtornos mentais comuns e estressores no trabalho entre professores de nove cursos da área da saúde de uma universidade particular ...
Tópico(s): Stress and Burnout Research
2015 - Fundação Oswaldo Cruz, Escola Politécnica de Saúde Joaquim Venâncio | Trabalho Educação e Saúde
Gilmar Reis, Eduardo Augusto dos Santos Moreira Silva, Daniela Carla Medeiros Silva, Lehana Thabane, Vitoria Helena de Souza Campos, Thiago Santiago Ferreira, Castilho Vitor Quirino dos Santos, Ana Maria Ribeiro Nogueira, Ana Paula Figueiredo Guimaraes Almeida, Leonardo Cançado Monteiro Savassi, Adhemar Dias de Figueiredo Neto, Carina Bitarães, Aline Cruz Milagres, Eduardo Diniz Callegari, Maria Izabel Campos Simplicio, Luciene Barra Ribeiro, Rosemary Oliveira, Ofir Harari, Lindsay A. Wilson, Jamie I. Forrest, Hinda Ruton, Sheila Sprague, Paula McKay, Christina M. Guo, Gordon Guyatt, Craig R. Rayner, David R. Boulware, Nicole Ezer, Todd C. Lee, Emily G. McDonald, Mona Bafadhel, Christopher Butler, Josue Rodrigues Silva, Mark Dybul, Edward J. Mills, Gilmar Reis, Eduardo Augusto dos Santos Moreira Silva, Daniela Carla Medeiros Silva, Castilho Vitor Quirino dos Santos, Ana Maria Ribeiro Nogueira, Ana Paula Figueiredo Guimaraes Almeida, Adhemar Dias de Figueiredo Neto, Leonardo Cançado Monteiro Savassi, Luciene Barra Ribeiro, Maria Izabel Campos Simplicio, Thiago Santiago Ferreira, Vitoria Helena de Souza Campos, Lehana Thabane, Jamie I. Forrest, Edward J. Mills, D. William Cameron, James Orbinski, Sonal Singh, Kristian Thorlund, Jonas Häggström, Heloísa A. Costa, Nayara S. Drumont, Stephanny Kelvyn Bessa, João V.B. Vieira, Vania R Campos, Rosemary Oliveira, Lineria HM Suterio, Josue Rodrigues Silva, Adelino de melo Freire, Ana Carolina Fialho Dias Rocha, Ana Paula de Faria Gonçalves, Andressa França, Carlos Eduardo Dias Igídio, Igor César de Oliveira Sousa, Iracema Luisa Quintino de Carvalho, Larissa Maria Manini Benavides, Patrícia de Oliveira Pereira, Phelipy Marques de Sousa, Sabrina de Almeida Lima, Silvia Helena Sousa Pietra Pedroso, Snaydia Viegas Resende, Wellington da Silva Rocha, Thamiris Caldeira Alves, Aline Lúcia de Jesus Martins, Amanda Gouvêa Mesquita, Amanda Larissa Alves Mendes, Anna Beatriz Oliveira Mendes, Anna Clara de Jesus Oliveira, Carolina Couto de Azevedo Cysne, Clara Bensemann Gontijo Pereira, Cecília Campos Siqueira, Ednilson Barbosa Dias, Emanuelle Cristina Soares Gonçalves, Fernanda Leal Guimarães, Flavio E Giorgeto, Gabriel Torga Saade Rodrigues, Gislânia Neres de Sousa, Júlia Campos de Rezende, Júlia Diniz Assis Moreira, Isabela Canabrava Soares, João Victor Barbosa Silveira, Joselaine Gomes de Souza, Juliana Marques Santos Ferreira, Kênia Sthéfhane Guimarães Gonçalves, Laura Campos Oliveira, Layane Maria de Almeida, Letícia Campos Siqueira, Letícia de Fátimas Costa, Lorena Gabrielle Miranda Maciel, Lorena Giovanna Silva Peixoto, Lorena Mesquita Alves, Luana Rosa Rodrigues, Leonardo Silva de Almeida, Marcela Luíza Amaral Resende Lara, Luíza Lanna França Reis, M. Horacio, Maria Eduarda Martins Soares, Maria Luiza Magalhães Parreiras, M. Siqueira, Mariana Cristina Flores Mariano, Marina Guimarães Bragatto, Matheus Andrade Almeida e Silva, Mayra Estefane Silva dos Santos, Mirele Augusta Batista Ribeiro, Nayara Santos Drumond, Pedro Hosken Fernandes Guimarães, Pollyana Maria Silva Diniz, Roberta Dumont Paiva Lopes, Rosemary Oliveira, Stephanny Kelvyn Bessa, Sheila Soares Anselmo, Tainara Silva Vieira, Tatiana Aparecida Gomes da Silva, Thais Campos Siqueira, Vânia Regina Carmo, Vitor Augusto Lima do Vale, Vitor Vilaça Oliveira, Wedsley Sander Lopes dos Santos, Aline Daniele de Almeida Abreu, Bernardo Saraiva Resende de Camargos, Camila Araújo Heringer, Daniel Jacinto Mendonça Filho, Eriane Damasia Faria de Almeida Abreu, Felipe augusto Pereira Barnabé, Felipe Alves Vieira, Gabriella Fagundes Carvalho, Higor Gomes Mussi, Hilton Cardoso Arruda Macedo, Igor Bernardes Caciquinho, João Pedro Ribeiro Santos, João Ricardo Garcia Costa, José Lauro Guimarães Cardoso, Júlia Berlim de Abreu, Lorena Rodrigues de Carvalho, Lorena Amaral de Oliveira, Luana Rocha Oliveira Matos, Marcela Ferreira Brito, Mariana Cavaliere Batista e Silva, Matheus Lucca Ângelo Costa Rodrigues, Mateus de Oliveira Ferreira, Murilo Passinati Perez, Natalia Batista Zanetti, Rafaela Ribeiro de Almeida, Sarah Jeniffer da Silva Jamar, Sofia Caporalli Barbosa, Sofia Vianna von Bentzeen Rios, Stella Silva Rosa, Thomaz Takashi Ferreira Morimoto, Verônica de Araújo Libânio costa, Vitor Augusto Alves da Silva, Amanda Cypestre Alves Batista, Ana Flávia Gomes Viana, Ângela Rodrigues Vieira Santos, Anna Luiza Ribeiro Flores, Arthur Guimarães Rodrigues Dutra, Bruna Luiza Maia, Clarisse Lourdes Nadú de Almeida, Daniel Domingues Barbosa, Daniela Medeiros, D Silva, Diuly Ane Faria Rezende, Felipe Menezes Andrade, Fernanda Rúbia Batista, Gabriela Ferreira Reis, Giovane Carvalho Constantino Ferreira de Paula, Geovani de Araújo Júnior, Henrique Amaral Fonseca Pires, Jéssica Aguilar da Silva, Isabela Lovatti Rovetta, Júlia Silva Rangel, Júlia Lima Soares de Paula, Juliana de Oliveira Costa, Lucas Júnio da Silva, Luiz Gustavo Fernandes Dias, Lívia Francino Oliveira, Lucas Rodrigues Pereira Barros, Lucas de Souza Gontijo Pessoa, Lucas Klier Silva, Maria Luísa Lara Lanza Stabile, Mariana da Rocha Assis Pinto, Nicholas Vanzin Cunha, Paloma Alister Vilela da Silva, Rafael Silva Rodrigues Soares, Thais Gomes de Oliveira, Victor Oliveira de Araújo, Wesley Costa Arcanjo, A Vanetti, Ana Carolina Araújo Lage Santos, Ariade Gomes Freitas, Felipe Viana Santos, Fernanda Freitas Pinheiro, Fernanda Perez Rocha, Filipe Viana Santos, Giulia de Jesus Marcolino, Humberto Drumond Filho, Isabela Gontijo Mendonça, Isadora Gomides Faria, José Victor Mendes Milhomem, Larissa Milagres Mol, Letícia de Fátima Costa, Marcelo Bernardes Rocha Júnior, Maria Constâncio Miranda, Nathália Euclides Gonçalves, Suzana Cristina Ricco, Thiago Araújo do Nascimento, Amanda Luiza do Espírito Santo Pinheiro, Ana Carolina Matos Ferreira, Ana Caroline Santos Silva, Ana Luiza Silva Taveira, Bruno Victor de Souza Lima, Débora Siqueira Diana, Emanuela Pontes Pereira Silveira, Francisca Lina Campos Gonçalves, Gabriel C. Costa, Geraldo César Barroso de Souza, Guilherme Aurelio D'Oliveira Alves, Isadora Luiza Teixeira Neto, Jordanna Porto Inácio, J. Silverio, Lara Silveira Marques, Larissa Martins do Nascimento, Larissa Oliveira Moreira, Lorena Luiza Soares de Oliveira, Lucas Eduardo Lessa Mussi, Lucas Medeiros Ruas, Luiza Nogueira Assis Barbosa, Luiz Otávio de Sousa, Marcelo Rodrigues da Costa Fernandes, Maria Eduarda Guimarães de Souza, Maria Thereza Figueiredo Bélem Calazans, Mariana Rodrigues Marinho de Bastos, Pedro Henrique Arcanjo Alvarenga, Quimberli Vassinave Cujuí, Rafaela Valadares Diniz, Rafael Cota Andrade Ferreira de Souza, Rita de Cássia Silva, Vinícius Alves Corrêa, Vinícius Carvalho de Oliveira, Vitória Aparecida Cunha, Viviane Costa Santos, Ana Paula Figueiredo Guimaraes Almeida, Ana Paula Guimarães Alves de Carvalho, Antônio Henrique Batista Jorge, Artur Pimenta Ribeiro, Elisângela Santos Sena, Cleide Rocha Veloso, Gonçalvino Eleutério Murta, Inara Maria Gomes Cardoso, João Warley Alves, Jorge Fernando Rocha Veloso, Joyce Souto Barbosa Pimenta de Figueiredo, Karolina Campos Sampaio Lopes, Larissa Vieira Souza, Loren Montanha Costa, Ludimila Pereira de Souza, Maria de Fátima César Lima, Maria Izabel Silveira Gonçalves, Marizete Gislaine Mendes, Mayra Darlliane Loiola Silva, Raissa Rocha e Fonseca, Samuel de Paiva Oliveira, Thiago Rodrigues Ferro, Aline Cruz Milagres, Ana Carolina Aguiar Estevam, Ana Martins de Oliveira, André Henrique de Sousa Oliveira, Carina Bitarães, Carla Stefany Oliveira França, Hayka K. Rodrigues Freire, Laís Aparecida dos Reis Gama, Laylla Michelle Pereira, Luciléia Alcântara Gomes e Silva, Patrícia Santana Assis, Regiane Aparecida de Andrade, Thaís de Paula Ferreira da Silva, Thiago de Alcântara César, Adriana Marcos Mendes Rabelo, Aline do Carmo Rosa, Ana Paula Vilas Boas Wherberth, André Gustavo Pinto de Souza, André Luiz Souza Gomes,
Background: Previous trials have demonstrated the effects of fluvoxamine alone and inhaled budesonide alone for prevention of disease progression among outpatients with COVID-19. Objective: To determine whether the combination of fluvoxamine and inhaled budesonide would increase treatment effects in a highly vaccinated population. Design: Randomized, placebo-controlled, adaptive platform trial. (ClinicalTrials.gov: NCT04727424) Setting: 12 clinical sites in Brazil. Participants: Symptomatic adults ...
American College of Physicians
Produção Nacional
Revisado por pares
João dos Reis Silva Júnior, Everton Henrique Eleutério Fargoni,
RESUMO O artigo analisa as mudanças políticas que redefiniram e estão redefinindo a educação superior brasileira e faz apontamentos para análise da correlação das forças econômicas com o momento histórico do Brasil, tendo origem na década final do século XX e se estendendo até o ano 2020. Caracteriza a composição do Programa Institutos e Universidades Empreendedoras e Inovadoras – Future-se, analisando o contraditório por meio dos intentos e elementos neoliberais introduzidos no texto do projeto. ...
Tópico(s): Evasion and Academic Success Factors
2020 - Centro de Estudos Educação e Sociedade | Educação & Sociedade
Produção Nacional
Thaísa Soares Crespo, João Marcus Oliveira Andrade, Deborah de Farias Lelis, Alice Crespo Ferreira, João Gabriel Silva Souza, Andreá Maria Eleutério de Barros Lima Martins, Sérgio Henrique Sousa Santos,
Diabetes mellitus (DM) is a public health problem, which requires enhanced self-care in order to avoid complications. However, cognitive impairment can reduce these abilities and may affect health literacy (HL) of patients in terms to understand and apply information. Therefore, this study evaluated the correlation between cognitive condition and HL related to medication adherence, physical activity and nutritional status among people living with DM.A cross-sectional study was carried out among elderly ...
Tópico(s): Diabetes Treatment and Management
2020 - Elsevier BV | IBRO Reports
Rute Castro, Lígia S. Nobre, Rute P. Eleutério, M. Thomaz, António Pires, Sandra Monteiro, Sónia Mendes, Ricardo A. Gomes, João J. Clemente, Marcos F. Q. Sousa, Filipe Pinto, Ana Carina Silva, Micael C. Freitas, Ana R. Lemos, Onome Akpogheneta, Lindsay Kosack, Marie‐Louise Bergman, Nádia Duarte, Paula Matoso, Júlia Costa, Tiago M. Bandeiras, Patrícia Gomes‐Alves, Carlos Penha‐Gonçalves, Jocelyne Demengeot, Paula M. Alves,
Serological assays are valuable tools to study SARS-CoV-2 spread and, importantly, to identify individuals that were already infected and would be potentially immune to a virus reinfection. SARS-CoV-2 Spike protein and its receptor binding domain (RBD) are the antigens with higher potential to develop SARS-CoV-2 serological assays. Moreover, structural studies of these antigens are key to understand the molecular basis for Spike interaction with angiotensin converting enzyme 2 receptor, hopefully ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2021 - Wiley | Biotechnology and Bioengineering
Produção Nacional
Revisado por pares
Bruna Botteon Della Coletta, Thiago Borges Jacob, Luana Aparecida de Carvalho Moreira, Karina Torres Pomini, Daniela Vieira Buchaim, Rachel Gomes Eleutério, Eliana de Souza Bastos Mazuqueli Pereira, Domingos Donizeti Roque, Marcelie Priscila de Oliveira Rosso, João Vitor Tadashi Cosin Shindo, Marco Antônio Húngaro Duarte, Murilo Priori Alcalde, Rui Seabra Ferreira, Benedito Barraviera, Jefferson Aparecido Dias, Jesús Carlos Andreo, Rogério Leone Buchaim,
The aim is to evaluate the effects of photobiomodulation therapy (PBMT) on the guided bone regeneration process (GBR) in defects in the calvaria of rats filled with biphasic calcium phosphate associated with fibrin biopolymer. Thirty male Wistar rats were randomly separated: BMG (n = 10), defects filled with biomaterial and covered by membrane; BFMG (n = 10), biomaterial and fibrin biopolymer covered by membrane; and BFMLG (n = 10), biomaterial and fibrin biopolymer covered by membrane and biostimulated with ...
Tópico(s): Dental Trauma and Treatments
2021 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Marise Fagundes Silveira, João Marôco, Rafael Silveira Freire, Andreá Maria Eleutério de Barros Lima Martins, Luiz Francisco Marcopito,
This study aimed to estimate the prevalence of impact of oral health conditions on physical and psychosocial dimensions among adolescents and to identify factors associated with severity of impact. The impact of oral health status was assessed by the instrument Oral Health Impact Profile (OHIP-14). The covariates were: socioeconomic status, habits and health care, use of dental services, and normative conditions of oral health. Structural equation modeling was performed, and 15.6% of adolescents ...
Tópico(s): Health disparities and outcomes
2014 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública
Ana Santos-Rebelo, Catarina García, Carla Eleutério, Ana Bastos, Sílvia Castro Coelho, Manuel A. N. Coelho, Jesús Molpeceres, Ana S. Viana, Lia Ascensão, João F. Pinto, Maria Manuela Gaspar, Patrícia Rijo, Catarina Pinto Reis,
Pancreatic cancer is the eighth leading cause of cancer death worldwide. For this reason, the development of more effective therapies is a major concern for the scientific community. Accordingly, plants belonging to Plectranthus genus and their isolated compounds, such as Parvifloron D, were found to have cytotoxic and antiproliferative activities. However, Parvifloron D is a very low water-soluble compound. Thus, nanotechnology can be a promising delivery system to enhance drug solubility and targeted ...
Tópico(s): Enhanced Oil Recovery Techniques
2018 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
Produção Nacional
Revisado por pares
João Gabriel Silva Souza, Bárbara Emanoele Costa Oliveira, Andreá Maria Eleutério de Barros Lima Martins,
Tópico(s): Oral microbiology and periodontitis research
2016 - Springer Science+Business Media | Quality of Life Research
Produção Nacional
Revisado por pares
Carolina Veloso Lima, Mayara dos Santos Noronha, Emily Jamily Medeiros de Menezes, Vanessa Stephane de Oliveira Araújo, Patrícia Helena Costa Mendes, Raquel Conceição Ferreira, Andrea Maria Eleutério de Barros Li Martins, João Gabriel Silva Souza,
Tópico(s): Dental Anxiety and Anesthesia Techniques
2022 - Springer Nature | Clinical Oral Investigations
Produção Nacional
Revisado por pares
José Roosevelt Cavalcante, João Paulo Aguiar Sampaio, João Tarcísio Alves Maia Filho, Renato Braga Vieira, José Eleutério, Roberto César Pereira Lima Júnior, Ronaldo A. Ribeiro, Paulo Roberto Carvalho Almeida,
PURPOSE: To investigate E-cadherin immunoexpression during cervical carcinogenesis. METHODS: We assessed the immunohistochemical expression of E-cadherin in squamous intraepithelial lesions (SIL - 52 cases), squamous cell carcinoma (SCC) of the uterine cervix (23 cases) and also in eight cases of cervicitis. RESULTS: The results show very different E-cadherin membrane expression levels when cervicitis (88%), SILs (73%) and SCC (17%) were compared. In SILs, higher E-cadherin loss was seen in less differentiated ...
Tópico(s): Cancer-related gene regulation
2014 - Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia | Acta Cirúrgica Brasileira
Produção Nacional
Monique Naiumy Soares, Carlos Corrêa Silva, Iago Rafael de Brito Guimarães, João Matheus Eleutério Corrêa,
Tópico(s): HIV/AIDS Research and Interventions
2019 - Brazilian Journal of Development | Brazilian Journal of Health Review
Jacinta O. Pinho, Mariana Matias, Vanda Marques, Carla Eleutério, Célia Fernandes, Lurdes Gano, Joana D. Amaral, Eduarda Mendes, Maria de Jesus Perry, João Nuno Moreira, Gert Storm, Ana Paula Francisco, Cecília M. P. Rodrigues, Maria Manuela Gaspar,
The aggressiveness of melanoma and lack of effective therapies incite the discovery of novel strategies. Recently, a new dual acting hybrid molecule (HM), combining a triazene and a ʟ-tyrosine analogue, was synthesized. HM was designed to specifically be activated by tyrosinase, the enzyme involved in melanin biosynthesis and overexpressed in melanoma. HM displayed remarkable superior antiproliferative activity towards various cancer cell lines compared with temozolomide (TMZ), a triazene drug in ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2022 - Elsevier BV | Biomedicine & Pharmacotherapy
Vera Marisa Costa, João Paulo Capela, Joana R. Sousa, Rute P. Eleutério, Patrícia Rodrigues, José Luís Dores‐Sousa, Rui A. Carvalho, Maria de Lourdes Bastos, José Alberto Duarte, Fernando Remião, M. Gabriela Almeida, Kurt J. Varner, Félix Carvalho,
Tópico(s): Synthesis and Biological Evaluation
2020 - Springer Science+Business Media | Archives of Toxicology
Produção Nacional
Revisado por pares
Renata Francine Rodrigues de Oliveira, João Gabriel Silva Souza, Desirée Sant’Ana Haikal, Efigênia Ferreira e Ferreira, Andreá Maria Eleutério de Barros Lima Martins,
The scope of this study is to establish the profile of elderly users of dental services provided by the Brazilian Unified Health System(SUS) and associated factors from the standpoint of equity. It involves an analytical cross-sectional study with hierarchical modeling conducted on the basis of a complex probabilistic sample of groups of the elderly (65-74 years of age) living in a densely populated Brazilian city. Independent variables were included relating to: socio-demographic characteristics, ...
Tópico(s): Patient Satisfaction in Healthcare
2016 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
Ana Paula dos Santos Xavier Braga, Diana Matos Silva, Deborah de Farias Lelis, Rogério Estevam Farias, Alanna Fernandes Paraíso, Sérgio Henrique Sousa Santos, Andreá Maria Eleutério de Barros Lima Martins, João Marcus Oliveira Andrade,
Preeclampsia (PE) is a multifunctional and multisystem disorder. Several factors favor the development of PE, including obesity. Cytokines are also expressed in the placenta, predisposing to local alterations that favor the development of distinct pathological processes, including PE. This study aimed to evaluate the apelin and visfatin mRNA expression in the placental tissue of women with preeclampsia and overweight/obesity and correlates with maternal and fetal variables.A cross-sectional analytical ...
Tópico(s): Cardiovascular, Neuropeptides, and Oxidative Stress Research
2023 - SAGE Publishing | Biological Research For Nursing
Produção Nacional
Revisado por pares
Carolina Vieira de Freitas, João Gabriel Silva Souza, Danilo Cangussu Mendes, Isabela Almeida Pordeus, Kimberly Marie Jones, Andreá Maria Eleutério de Barros Lima Martins,
To identify the prevalence and the severity of malocclusions and to analyze factors associated with the need for orthodontic treatment of Brazilian adolescents.
Tópico(s): Dental Anxiety and Anesthesia Techniques
2015 - Elsevier BV | Revista Paulista de Pediatria