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From Peter Hazelhurst, By Michael Horsnell, , John Witherow, Richard Ford, By Clifford Webb Midlands Industrial Correspondent, By Frances Gibb, By George Clark Political Correspondent, From Robert Fisk, From Paul Routledge Labour Editor, By Fred Emery Political Editor, By a Staff Reporter, By Michael Baily Transport Correspondent, From Annabel Ferriman Health Services Correspondent, By Ian Bradley, By Edward Townsend, By Our Political Editor, From Our Correspondent, By John Roper, From Christopher Warman, By Hugh Clayton Agriculture Correspondent, By Nicholas Timmins, From Arthur Osman, By Henry Stanhope Defence Correspondent, By John Young Planning Reporter, From Our Education Correspondent, By Kenneth Gosling Arts Reporter, By Harry Golombek Chess Correspondent, By Pat Healy Social Services Correspondent, By Diana Geddes Education Correspondent, By Lucy Hodges, By Arthur Reed Air Correspondent, By Stanley Baldwin, From Patricia Clough, From David Wood, From Charles Hargrove, From Robert Schuil, From Patrick Brogan, By Hugh Noyes Parliamentary Correspondent, From Patrick Knight, by Arrigo Levi, From Christopher Walker, From Tewfik Mishlawi, From Michael Leapman, From Ivor Davis, From Hasan Akhtar, From Denis Reinhardt, Dessa Trevisan, From Richard Hughes, Michael Ratcliffe, Jacky Gillott, H. R. F. Keating, Michael Church, Ned Chaillet, Brian Martin, Nikolai Tolstoy, John Hackett, Jenny Woolf, Shona Crawford Poole, Hugh Clayton, John Higgins, John Percival, Joan Bakewell, Stanley Sadie, Barry Millington, Ronald Butt, Bernard Levin, Alan Hamilton, CARLOS BRAGA, , JOAOUIM JOSE, , BARBOSA ROMERO, , JULIO BARREIROS, MARTINS, , JOSE MANUEL VAZ, , CARLOS AUGUSTO, , G. MOURA BRANCO, , HERNANI LOPES, , da SILVA MALA, , L. CHAINHO, , PEREIRA, , L. de JESUS, SANTOS SOARES, , S. SANTOS, , JOAO PINHEIRO, , C. A. A. BERNARDO, , JOAO FERREIRA, , MARIA ISABEL, CALADO FERREIRA, , VIRGINIA M. GERGORIO, , EDITE M. G. P. FERNANDES, , JOSE MANUEL E. VALENCA, , MARIA RAQUEL VALENCA, , RAUL VIDAL, MARIO de ARAUJO, , REX DAVIS, , T. A. BIRRELL, , HUGH PESKETT, , W. E. BAUGH, , IAIN MONCREIFFE OF THAT ILK, , W. H. HANKIN, , ANTONY WHITAKER, , A. L. S. CORNER, , RICHARD RITGHIE, , TITO BENADY, , KENNET, , NOEL ANNAN, , MICHAEL HOLROYD, , DAVID GARNETT, , VICTOR PRITCHETT, , EVAN LUARD, , D. R. MIDGLEY, , ADRIAN C. BOULT, , GERTRUDE M. BANNISTER, , By the Staff of Nature, From Our Own Correspondent, By Geraldine Norman Sale Room Correspondent, By Clifford Longley Religious Affairs Correspondent, Cyril Bainbridge, By our Arts Reporter, W. W. W. and J. B. write:, Baroness Airey of Abingdon writes:, By Mitchell Platts, By Keith Macklin, By John Nicholls, John Young, From Richard Streeton, By John Woodcock Cricket Correspondent, By Michael Seely, By Norman Fox Football Correspondent, By Our Rifle Shooting Correspondent, By Pamela Macgregor-Morris, By John Watson, By Peter Hill Industrial Editor, By David Felton Labour Reporter, By Roman Eisenstein Banking Correspondent, By John Whitmore Financial Correspondent, By Tim Jones, From Michael Hornsby, By Peter Wilson-Smith, From Frank Vogl, William Olsen, By Kenneth Owen Technology Editor, By Bill Johnstone, By Margaret Stone, By Nicholas Hirst Energy Correspondent, MELVILLE BERNSTEIN, , MRS M. D. LOVEDAY, , JOHN GADD, , A. C. PARSONS, , J. B. DANEL, , HUGH CAWDRON, , BY THE FINANCIAL EDITOR, Ross Davies, David Blake, Derek Harris, Michael Prest Mining correspondent, By Our Financial Staff, By Rosemary Unsworth, Peter Davalle,

News: EEC budget is approved seven months late, Latest pamphlets Religious beliefs of Elgar, The Times Cook Separate ways with eggs, Kidnap victim is ...

1980 - Gale Group | TDA

Artigo Acesso aberto Brasil Produção Nacional

Jéssyca Dellinhares Lopes Martins, Mácio Farias de Moura, João Paulo Ferreira de Oliveira, Marcos De Oliveira, Cathylen Almeida Félix Galindo,

Onde o cultivo do feijão é realizado por agricultores familiares sem grandes investimentos em insumos, a adubação orgânica pode vir a suplementar ou, até mesmo, substituir os adubos químicos, a longo prazo, na lavoura. Diante disso, objetivou-se avaliar o desempenho produtivo do feijão comum cultivado com esterco bovino, biofertilizante, inoculante, adubação mineral e diferentes combinações desses. O experimento foi realizado em condições de sequeiro, no município de São João-PE, no ano agrícola ...

Tópico(s): Growth and nutrition in plants

2016 - FUNDAÇÃO UNIVERSIDADE FEDERAL DE RORAIMA | Revista Agro mbiente On-line

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Fábio Ferreira de Moura, João Eduardo Nunes Salles, Osama Hamdy, Walmir Coutinho, Deise Regina Baptista, Alexander Benchimol, Albert Marchetti, Refaat Hegazi, Jeffrey I. Mechanick,

The prevalence of obesity, pre-diabetes, and type 2 diabetes (T2D) is increasing worldwide, especially in the developing nations of South America. Brazil has experienced an exponential increase in the prevalence of these chronic non-communicable diseases. The rising prevalence is probably due to changing eating patterns, sedentary living, and a progressive aging of the population. These trends and their underlying causes carry untoward consequences for all Brazilians and the future of Brazilian public ...

Tópico(s): Obesity, Physical Activity, Diet

2015 - Multidisciplinary Digital Publishing Institute | Nutrients

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Andressa Paula de Oliveira, Stefany Moura, Luiz Cláudio Ferreira Pimentel, João G. de Oliveira Neto, Rafael Ferreira Dantas, Floriano Paes Silva, Mônica M. Bastos, Núbia Boechat,

Tyrosine kinase enzymes are among the primary molecular targets for the treatment of some human neoplasms, such as those in lung cancer and chronic myeloid leukemia. Mutations in the enzyme domain can cause resistance and new inhibitors capable of circumventing these mutations are highly desired. The objective of this work was to synthesize and evaluate the antiproliferative ability of ten new analogs that contain isatins and the phenylamino-pyrimidine pyridine (PAPP) skeleton, the main pharmacophore ...

Tópico(s): PI3K/AKT/mTOR signaling in cancer

2022 - Multidisciplinary Digital Publishing Institute | Molecules

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Marina de M. Silva, Taís Soares Macedo, Helena Mariana Pitangueira Teixeira, Diogo Rodrigo Magalhães Moreira, Milena Botelho Pereira Soares, Ana Ligia da Costa Pereira, Vanessa de Lima Serafim, Francisco Jaime Bezerra Mendonça, Maria do Carmo Alves de Lima, Ricardo Olímpio de Moura, Edeildo Ferreira da Silva‐Júnior, João Xavier de Araújo‐Júnior, Maria Dayanne de A. Dantas, Eduarda de O. O. Nascimento, Thamilla Maria S. Maciel, Thiago Mendonça de Aquino, Isis Martins Figueiredo, Josué Carinhanha Caldas Santos,

Acridines are considered an important class of compounds due to their wide variety of biological activities. In this work, we synthesized four acridine derivatives (1-4) and evaluated their biological activity against the Plasmodium falciparum W2 line, as well as studied the interaction with ctDNA and HSA using spectroscopic techniques and molecular docking. The acridine derivative 2 (IC50 = 0.90 ± 0.08 μM) was more effective against P. falciparum than primaquine (IC50 = 1.70 ± 0.10 μM) and similar to amsacrine ( ...

Tópico(s): Synthesis and Biological Evaluation

2018 - Elsevier BV | Journal of Photochemistry and Photobiology B Biology

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Antônio Gabriel de Sousa Moura, G. M. Santana, Paulo Michel Pinheiro Ferreira, João Marcelo de Castro e Sousa, Ana Paula Peron,

Despite their great importance for the food industry, flavorings, in general, raise a number of questions regarding their cytotoxicity, mutagenicity and carcinogenicity, since, in the literature, there are few studies found evaluating the toxicity on the systemic and cellular level, of these chemical compounds. The root meristems of Allium cepa (onion) are widely used for the assessment of toxicity of chemical compounds of interest. Thus, this study aimed to evaluate, in A. cepa meristematic cells, ...

Tópico(s): Potato Plant Research

2016 - Instituto Internacional de Ecologia (Brazil) | Brazilian Journal of Biology

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ariane Neves de Moura, Jetson Lemos Ferreira, João Batista Ribeiro Martins, Marden Valente de Souza, Nicolau Apoena Castro, M. T. D. Orlando,

The microstructure, crystallographic texture, strain hardening in the hole edge‐punched and stretch‐flangeability of hot‐rolled multiphase sheet steel is investigated by scanning electron microscopy, electron backscatter diffraction, and microhardness measurements. The results show that the strain hardening in the hole edge‐punched is not the main factor that influences the hole expansion ratio. The bainite fraction, average grain area, and kernel average misorientation distribution mean are microstructure ...

Tópico(s): Metallurgy and Material Forming

2020 - Wiley | steel research international

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Alessandra M. M. Lucena, Cássio Ricardo de Medeiros Souza, Jéssica Teixeira Jales, Paulo Marcos da Matta Guedes, George Emmanuel Cavalcanti de Miranda, Adolpho Marlon Antoniol de Moura, João Xavier de Araújo‐Júnior, George João Ferreira do Nascimento, Kátia Castanho Scortecci, Bárbara V. O. Santos, Janeusa Trindade de Souto,

Caulerpin (CLP), an alkaloid from algae of the genus Caulerpa, has shown anti-inflammatory activity. Therefore, this study aimed to analyze the effect of CLP in the murine model of peritonitis and ulcerative colitis. Firstly, the mice were submitted to peritonitis to evaluate which dose of CLP (40, 4, or 0.4 mg/kg) could decrease the inflammatory infiltration in the peritoneum. The most effective doses were 40 and 4 mg/kg. Then, C57BL/6 mice were submitted to colitis development with 3% dextran sulfate ...

Tópico(s): Echinoderm biology and ecology

2018 - Multidisciplinary Digital Publishing Institute | Marine Drugs

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Artigo Brasil Produção Nacional Revisado por pares

David da Cunha Valença, Stéfanie Menezes de Moura, João Travassos‐Lins, Márcio Alves‐Ferreira, Leonardo Oliveira Médici, Bianca Ortiz da Silva, Andrew Macrae, Fernanda Reinert,

Drought-tolerant species, such as Setaria viridis, a C4 model plant, make physiological and biochemical adjustments water limitation and recover from the stress upon its release. We investigated S. viridis (A10.1 accession) responses to continuing osmotic stress. The osmotic stress was imposed using polyethylene glycol (PEG) 8000 (7.5%) for 10 days. Morphological traits and stomatal conductance were measured daily for the 10 days. On days 6 and 10, the following traits were measured separately for ...

Tópico(s): Plant nutrient uptake and metabolism

2020 - Elsevier BV | Plant Physiology and Biochemistry

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Artigo

Kanika Dharmayat, Antonio J. Vallejo‐Vaz, C. Stevens, Julia Brandts, Alexander R.M. Lyons, Urh Grošelj, Marianne Abifadel, Carlos A. Aguilar‐Salinas, Khalid F. AlHabib, Mutaz Al-Khnifsawi, Wael Almahmeed, Fahad Alnouri, Rodrigo Alonso, Khalid Al‐Rasadi, Tester F. Ashavaid, Maciej Banach, Sophie Béliard, Christoph J. Binder, Mafalda Bourbon, Krzysztof Chlebus, Pablo Corral, Diogo Cruz, Olivier Descamps, Euridiki Drogari, Ronen Durst, М. В. Ежов, Jacques Genest, Mariko Harada‐Shiba, Kirsten B. Holven, Steve E. Humphries, Weerapan Khovidhunkit, Katarina Lalić, Ulrich Laufs, Evangelos Liberopoulos, Jeanine E. Roeters van Lennep, Marcos M. Lima-Martínez, Jie Lin, Vincent Maher, Winfried März, André R. Miserez, Olena Mitchenko, Hapizah Nawawi, Andrie G. Panayiotou, György Paragh, Arman Postadzhiyan, Ashraf Reda, Željko Reiner, Ximena Reyes, Fouzia Sadiq, Amirhossein Sahebkar, Heribert Schunkert, Aleksandr B. Shek, E.S.G. Stroes, Ta‐Chen Su, Subramaniam Tavintharan, Andrey V. Susekov, Alejandra Cárdenas, Thanh Huong Truong, Alexandros D. Tselepis, Branislav Vohnout, Luya Wang, Shizuya Yamashita, Ahmad Al‐Sarraf, Nasreen Al-Sayed, Kairat Davletov, Bambang Dwiputra, Dan Gaiţă, Meral Kayıkçıoğlu, Gustavs Latkovskis, Adéle Marais, Anne Thushara Matthias, Erkin М Мirrakhimov, Børge G. Nordestgaard, Žaneta Petrulionienė, Belma Pojskić, Wilson E. Sadoh, Myra Tilney, Brian Tomlinson, Anne Tybjærg‐Hansen, Margus Viigimaa, Alberico L. Catapano, Tomáš Freiberger, G. Kees Hovingh, Pedro Mata, Handrean Soran, Frederick J. Raal, Gerald F. Watts, Laura Schreier, Virginia Bañares, Susanne Greber‐Platzer, Margot Baumgartner-Kaut, Charlotte de Gier, Hans Dieplinger, Florian Höllerl, Reinhold Innerhofer, Daniela Karall, Julia Lischka, Bernhard Ludvik, Martin Mäser, Sabine Scholl‐Bürgi, Alexandra Thajer, Hermann Toplak, Fabian Demeure, Ann C. Mertens, Jean‐Luc Balligand, Xavier Stéphenne, Étienne Sokal, Ivo Petrov, Assen Goudev, Fedya Nikolov, Snejana Tisheva, Yoto Yotov, Ivajlo Tzvetkov, Robert A. Hegele, Daniel Gaudet, Liam R. Brunham, Isabelle L. Ruel, Brian W. McCrindle, Ada Cuevas, Dražen Perica, Phivos Symeonides, Efstratios Trogkanis, Andreas Kostis, Andreas L. Ioannou, Angeliki Mouzarou, Anthoula Georgiou, Andreas Stylianou, George Miltiadous, Paris Iacovides, Constantinos Deltas, Michal Vrablı́k, Zuzana Urbanová, Pavel Ješina, Lukáš Tichý, J Hyánek, Jana Dvořáková, Jana Čepová, Josef Sykora, Kristyna Buresova, Michal Pipek, Eva Pistkova, Ivana Bartkova, Astrid S ulakova, Lenka Ťoukálková, Michaela Špenerová, Jan Malý, Marianne Benn, Ahmed Bendary, Atef Elbahry, Jean Ferrières, Dorota Ferrières, Noël Peretti, Éric Bruckert, Antonio Gallo, René Valéro, Florian Mourre, Karine Aouchiche, Rachel Reynaud, Patrick Tounian, Julie Lemale, Franck Boccara, Philippe Moulin, Sybil Charrières, Mathilde Di Filippo, Bertrand Cariou, François Paillard, Caroline Dourmap, A. Pradignac, Bruno Vergès, Isabelle Simoneau, Michel Farnier, Yves Cottin, Cécile Yelnik, R. Hankard, François Schiele, Vincent Durlach, Ariane Sultan, Alain Carrié, Jean‐Pierre Rabès, Veronika Sanin, Raphael Schmieder, Sara Ates, Christos V. Rizos, Ioannis Skoumas, Κωνσταντίνος Τζιόμαλος, Lοukianos S. Rallidis, Vasilios Kotsis, Michael Doumas, Emmanouil Skalidis, Genovefa Kolovou, Vana Kolovou, Anastasia Garoufi, Iosif Koutagiar, Georgios Polychronopoulos, Estela Kiouri, Christina Antza, E. Zacharis, Achilleas Attilakos, George Sfikas, Charalambos Koumaras, Panagiotis Anagnostis, Georgia Anastasiou, Georgé Liamis, P Adamidis, Haralambos Milionis, Vaia Lambadiari, Stella Stabouli, Theodosios D. Filippatos, Vasiliki Mollaki, Anastasia Tsaroumi, Frida Lamari, Pavlos Proyias, Mariann Harangi, Lakshmi Lavanya Reddy, Swarup A.V. Shah, Chandrashekhar K. Ponde, Jamshed Dalal, J.P.S. Sawhney, Ishwar C. Verma, Susan Hosseini, Tannaz Jamialahmadi, Mohammed Alareedh, Foaad Shaghee, Sabah Hasan Rhadi, Maryam Abduljalal, Sarmad Alfil, Huda Kareem, Hofit Cohen, Eran Leitersdorf, Daniel Schurr, Shoshi Shpitzen, Marcello Arca, Maurizio Averna, Stefano Bertolini, S. Calandra, Patrizia Tarugi, Manuela Casula, Federica Galimberti, Marta Gazzotti, Elena Olmastroni, Riccardo Sarzani, Claudio Ferri, Elena Repetti, Francesco Giorgino, Patrizia Suppressa, Antonio Bossi, Claudio Borghi, Sandro Muntoni, Francesco Cipollone, Roberto Scicali, Arturo Pujia, Angelina Passaro, Martina Berteotti, Valerio Pecchioli, Livia Pisciotta, Giuseppe Mandraffino, Fabio Pellegatta, Giuliana Mombelli, Adriana Branchi, A.M. Fiorenza, Cristina Pederiva, José Pablo Werba, Gianfranco Parati, Fabio Nascimbeni, Lorenzo Iughetti, Giuliana Fortunato, Raimondo Cavallaro, Gabriella Iannuzzo, Paolo Calabrò, Angelo B. Cefalù, Maria Elena Capra, Alberto Zambon, Matteo Pirro, Francesco Sbrana, Chiara Trenti, Ilenia Minicocci, Massimo Federici, Maria Del Ben, Paola Sabrina Buonuomo, Simona Moffa, A. E. Pípolo, Nadia Citroni, Ornella Guardamagna, Salvatore Lia, Andrea Benso, Gianni Biolo, Lorenzo Maroni, Alessandro Lupi, Luca Bonanni, Elisabetta Rinaldi, Maria Grazia Zenti, Daisaku Masuda, Linda Mahfouz, S Jambart, Carine Ayoub, Youmna Ghaleb,

Summary Background Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults with familial hypercholesterolaemia were diagnosed before age 18 years via current diagnostic approaches, which are derived from observations in adults. We aimed to characterise children and adolescents with heterozygous familial hypercholesterolaemia (HeFH) and understand current approaches to the identification and management of familial hypercholesterolaemia to ...

Elsevier BV

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Artigo Brasil Produção Nacional Revisado por pares

Giselli Scaini, Tássia Tonon, Carolina Fischinger Moura de Souza, Patricia F. Schuk, Gustavo C. Ferreira, João Seda Neto, Tatiana Amorin, Ida Vanessa Döederlein Schwartz, Emílio L. Streck,

Tópico(s): Biochemical Acid Research Studies

2016 - Springer Science+Business Media | Molecular Neurobiology

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Artigo Brasil Produção Nacional Revisado por pares

Giselli Scaini, Tássia Tonon, Carolina Fischinger Moura de Souza, Patrícia Fernanda Schuck, Gustavo C. Ferreira, João Quevedo, João Seda Neto, Tatiana Amorim, José Simon Camelo, Ana Vitória Barban Margutti, Rafael Hencke Tresbach, Fernanda Sperb‐Ludwig, Raquel Boy, Paula Frassinetti Vasconcelos de Medeiros, Ida Vanessa Döederlein Schwartz, Emílio L. Streck,

Abstract Maple syrup urine disease (MSUD) is an autosomal recessive inherited disorder that affects branched‐chain amino acid (BCAA) catabolism and is associated with acute and chronic brain dysfunction. Recent studies have shown that inflammation may be involved in the neuropathology of MSUD. However, these studies have mainly focused on single or small subsets of proteins or molecules. Here we performed a case‐control study, including 12 treated‐MSUD patients, in order to investigate the plasmatic ...

Tópico(s): Adipose Tissue and Metabolism

2018 - Springer Science+Business Media | Journal of Inherited Metabolic Disease

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Artigo Brasil Produção Nacional Revisado por pares

José Pinheiro de Moura, João Viana da Fonseca Neto, Ernesto Franklin Marçal Ferreira, Evandro Martins Araújo Filho,

The tuning of proportional–integral–derivative (PID) controllers has been extensively used in the industry, this adjustment is performed by means of conventional methods, such as the Ziegler–Nichols and trial-and-error that often fails to address inherent complexity of industrial processes. To overcome these problems of PID tuning, a neurocomputing adaptive novel methodology is presented in this paper. The proposed methodology is based on a structured artificial neural network (S-ANN) and a propagation ...

Tópico(s): Fault Detection and Control Systems

2020 - Elsevier BV | Neurocomputing

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Petitions Acesso aberto

... Amazon and Gurupá, from the " Noticiario Maranhense" of João de Souza Ferreira, Provedor da Fazenda dos Ausentes do Gras Pará ; ... 221. 31. Extract from the "America Abreviada " of João de Sousa Ferreira, described as "Presbitero da Ordem de S. Pedro" ( ...

1729 - Gale Group | SASII

Revisão Acesso aberto Brasil Produção Nacional Revisado por pares

Marcello Casaccia Bertoluci, João Eduardo Nunes Salles, José Silva‐Nunes, Hermelinda Cordeiro Pedrosa, Rodrigo O. Moreira, Rui Duarte, Davide Carvalho, Fábio Rogério Trujilho, João Filipe Cancela dos Santos Raposo, Erika B. Parente, Fernando Valente, Fábio Ferreira de Moura, Alexandre Hohl, Miguel Melo, Francisco Araújo, Rosa Maria Príncipe, Rosane Kupfer, Adriana Costa e Forti, Cynthia Melissa Valério, Hélder Ferreira, João Manuel Sequeira Duarte, José Francisco Kerr Saraiva, Melanie Rodacki, Maria Helane Costa Gurgel Castelo, Mariana P. Monteiro, Patrícia Branco, Pedro Manuel Patricio de Matos, Pedro Carneiro de Melo Pereira de Magalhães, R Betti, Rosângela Réa, Thaisa Dourado Guedes Trujilho, Lana Catani Ferreira Pinto, Cristiane Bauermann Leitão,

Abstract Background In current management of type 2 diabetes (T2DM), cardiovascular and renal prevention have become important targets to be achieved. In this context, a joint panel of four endocrinology societies from Brazil and Portugal was established to develop an evidence-based guideline for treatment of hyperglycemia in T2DM. Methods MEDLINE (via PubMed) was searched for randomized clinical trials, meta-analyses, and observational studies related to diabetes treatment. When there was insufficient ...

Tópico(s): Metabolism, Diabetes, and Cancer

2020 - BioMed Central | Diabetology & Metabolic Syndrome