Scott A. Soleimanpour, Aditi Gupta, Marina Bakay, Alana Ferrari, David Groff, João Fadista, Lynn A. Spruce, Jake A. Kushner, Leif Groop, Steven H. Seeholzer, Brett A. Kaufman, Hákon Hákonarson, Doris A. Stoffers,
Clec16a has been identified as a disease susceptibility gene for type 1 diabetes, multiple sclerosis, and adrenal dysfunction, but its function is unknown. Here we report that Clec16a is a membrane-associated endosomal protein that interacts with E3 ubiquitin ligase Nrdp1. Loss of Clec16a leads to an increase in the Nrdp1 target Parkin, a master regulator of mitophagy. Islets from mice with pancreas-specific deletion of Clec16a have abnormal mitochondria with reduced oxygen consumption and ATP concentration, ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2014 - Cell Press | Cell
João R. Vaz, Boman R. Groff, Douglas A. Rowen, Brian A. Knarr, Nicholas Stergiou,
Walking with different types of cueing/stimulus (i.e. auditory, visual) has been shown to alter gait variability, thus emerging as an innovative therapeutical tool to restore abnormal gait variability in clinical populations. However, the majority of the research in this area has focused on auditory stimuli while visual stimuli are an understudied alternative that needs more attention, particularly due to the natural dependence on vision during walking. Furthermore, the time differences between the ...
Tópico(s): stochastic dynamics and bifurcation
2019 - Elsevier BV | Neuroscience Letters
Construção social da memória em torno a João Baptista Groff e a ilusão biográfica, de Juan Cruz Galigniana
Tópico(s): Photographic and Visual Arts
2017 - UNIVERSIDADE FEDERAL DO PARANÁ | Revista NEP - Núcleo de Estudos Paranaenses da UFPR
Claudia Crimi, Alberto Noto, Fabiana Madotto, Mariachiara Ippolito, Santi Nolasco, Raffaele Campisi, Stefano De Vuono, Giuseppe Fiorentino, Ioannis Pantazopoulos, Athanasios Chalkias, Alessandro Libra, Alessio Mattei, Raffaele Scala, Enrico Clini, Begüm Ergan, Manel Luján, João Carlos Winck, Antonino Giarratano, Annalisa Carlucci, Cesare Gregoretti, Paolo Groff, Andrea Cortegiani,
Rationale In patients with COVID-19 pneumonia and mild hypoxaemia, the clinical benefit of high-flow nasal oxygen (HFNO) remains unclear. We aimed to examine whether HFNO compared with conventional oxygen therapy (COT) could prevent escalation of respiratory support in this patient population. Methods In this multicentre, randomised, parallel-group, open-label trial, patients with COVID-19 pneumonia and peripheral oxygen saturation (SpO 2 ) ≤92% who required oxygen therapy were randomised to HFNO or COT. ...
Tópico(s): COVID-19 Clinical Research Studies
2022 - BMJ | Thorax
Produção Nacional
Revisado por pares
Aline Aparecida Groff, Juliana da Silva, Emilene Arusievicz Nunes, Martus Ianistcki, Temenouga Nikolova Guecheva, Alzira Miranda de Oliveira, Christiane Patrícia Feitosa de Oliveira, Adalberto Luís Val, João Antônio Pêgas Henriques,
Ultraviolet radiation is known to cause adverse effects to aquatic species and aquatic environments. The fish Colossoma macropomum (tambaqui) and Arapaima gigas (pirarucu) live in the Amazon basin, near the Equator, and thus receive high intensity of ultraviolet radiation. Deforestation further aggravates the situation by reducing shade at ground level. The aim of this study was to evaluate the genotoxic effects of UVA and UVB radiation on erythrocytes of tambaqui and pirarucu fish using Micronuclei ...
Tópico(s): bioluminescence and chemiluminescence research
2010 - Elsevier BV | Journal of Photochemistry and Photobiology B Biology
Produção Nacional
Sheyla Olívia Groff Birro, Jurandyr Luciano Sanches Ross, João Batista Pereira Cabral,
In recent decades, the construction of reservoirs (Small Hydroelectric Centrals and Hydroelectric Power Plants) in hydrographic basins has caused several changes in the landscape, making it necessary to evaluate the synergistic and cumulative effects resulting from the environmental impacts caused by the set of hydroelectric projects. Changes in natural components can result in a loss of system functionality and disruption of its state of balance, which can be assessed through environmental fragility. ...
Tópico(s): Hydropower, Displacement, Environmental Impact
2021 - Centro de Estudos em Geografia e Ordenamento do Territorio | GOT - Geography and Spatial Planning Journal
Rodrigo Romao, João L. Pippi Salle, Cheryl Shuman, Rosanna Weksberg, Víctor Figueroa, Bryce Weber, Darius Bägli, Walid A. Farhat, Ronald Grant, J. Ted Gerstle, Armando J. Lorenzo,
... and Research, Inc.FiguresReferencesRelatedDetailsCited byKhondker A, Jain A, Groff M, Brzezinski J, Lorenzo A and Zappitelli M ( ... Toronto, Ontario, Canada More articles by this author João L. Pippi Salle Division of Urology, The Hospital ...
Tópico(s): Childhood Cancer Survivors' Quality of Life
2012 - Lippincott Williams & Wilkins | The Journal of Urology
Natalie Shenker, João Aprígio, Sertaç Arslanoğlu, Nant San San Aye, Anne Bærug, Naomi Bar Yam, Debbie Barnett, Roopa Bellad, Enrico Bertino, B. Adhisivam, Ketan Bharadva, Anne Bille Olin, Claude Billeaud, Rachel Buffin, Tanya Cassidy, Ruchika Sachdeva, Vanessa Clifford, Anna Coutsoudis, Sila Deb, Andreja Domjan, Li-Jung Fang, Janette Festival, Anthea Franks, Nadia Raquel García‐Lara, Antoni Gayá, Branka Golubiú-Úepuliú, Lindsay Groff, Anne Grøvslien, Erin Hamilton Spence, Mohammad Heidarzadeh, Mohammad Bagher Hosseini, Jackie Hughes, Kiersten Israel‐Ballard, Kajal Jain, Suksham Jain, Selvaraj Jayaraman, Frances Jones, Pratibha Kale, Jayendra Kasar, Angela Kithua, Laura D Klein, Daniel Klotz, Yungchieh Lin, Liu Xi-hong, Laraine Lockhart Borman, Josefin Lundstrom, Andreas Malzacher, Kimberly Mansen, Roger Mathisen, Radmila Mileusnić-Milenović, Zaw Win Moe, Guido E. Moro, Suchandra Mukherjee, San San Myint, Sushma Nangia, Sopapan Ngerncham, Faith Njeru, Estrella J Olonan-Jusi, Gillian Opie, Aunchalee E. L. Palmquist, Penny Reimers, Maryam Saboute, Pauline Sakamoto, Sybil Sanchez, Natalie Shenker, Himabindu Singh, Jai Prakash Singh, Poonam Singh, Marta Staff, Christine Sulfaro, Tran Thi Hoang, Annika Tiit-Vesingi, Satish Tiwari, Johannes B. van Goudoever, Amy Vickers, Mary Waiyego, Gillian Weaver, Aleksandra Wesołowska, Jenny Wright,
When a mother's own milk is not available, WHO recommends pasteurised donor human milk as the first alternative.1WHODonor human milk for low-birth-weight infants.https://www.who.int/elena/titles/donormilk_infants/en/Date: 2019Date accessed: April 30, 2020Google Scholar Human milk banks screen and recruit donors, and have wide-ranging precautions to ensure the safety of donor milk. Screened donor milk principally feeds babies of very low birthweight, protecting them from a range of complications, ...
Tópico(s): COVID-19 Impact on Reproduction
2020 - Elsevier BV | The Lancet Child & Adolescent Health
Produção Nacional
Luís Gustavo Corbellini, P. A. Vasconcellos, João Batista Pereira de Carvalho, Héber Eduardo Hein, A. C. Groff, J. R. M. Almeida, B. Todeschini, Adriana Aparecida Costa, Gabriella Trombini Machado, F. O. Brandão,
Tópico(s): Biotechnology and Related Fields
2011 - | Revista de Educação Continuada em Medicina Veterinária e Zootecnia do CRMV-SP
Produção Nacional
Fernanda Luísa Ramalho, Assunção Andrade de Barcelos, João Batista Pereira Cabral, Sheyla Olívia Groff Birro,
Atualmente observa-se que o ser humano utiliza os espaços segundo suas necessidades e seus valores individuais ou coletivos, o que afeta o equilíbrio dinâmico da natureza. Nesse sentindo, existe uma necessidade em encontrar explicações e soluções por parte de pesquisadores para os impactos que são gerados diante das intervenções do homem ao meio ambiente. Com isso, o trabalho tem como objetivo principal, identificar as principais atividades antrópicas na bacia hidrográfica do Córrego Matriz no período ...
Tópico(s): Environmental Sustainability and Education
2019 - UNIVERSIDADE FEDERAL DE GOIÁS | Geoambiente on-line
R Kao, A. Rajagopalan, Andrew Beckett, Andrew Beckett, Rex R, Seema Shah, James P. Waddell, M. A. Boitano, S. Faidi, O. Babatunde, F. H. Lawson, Alfred J. Grant, Monisha Sudarshan, Monisha Sudarshan, M. Takashashi, Melissa Waggott, Jacinthe Lampron, A. Post, Elmus Beale, Niklas Bobrovitz, Tanya L. Zakrison, Andrew Smith, Mohammed Bawazeer, C. Evans, Thomas J. Leeper, Daniel J. Kagedan, Tara Grenier, J. Rezendo-Neto, Derek J. Roberts, David R. Roberts, P. Stark, Regan J. Berg, Sunil Mehta, Paula J. Gardner, L. Moore, Michael Vassilyadi, L. Moore, L. Moore, Blaine Hoshizaki, João Rezende-Neto, Ingrid Slaba, A. Ramesh, Alisa Grigorovich, N. Parry, C. Pajak, B. Rosenbloom, Anton Grunfeld, Rardi van Heest, Janaína da Silva Gonçalves Fernandes, Jay Doucet, S. Schooler, Jaleel Ali, Barbara Klassen, Maria Santana, Amanda McFarlan, Chris Ball, Christopher Blackmore, João Rezende-Neto, Berhanu Kidane, C. Hicks, Maureen Brennan, Maureen Brennan, Alexandra M. Harrington, Anne Sorvari, Tony Stewart, Nancy Biegler, Ved Prakash Chaubey, Bonnie Tsang, S. Benjamin, A. Hogan, J. Fraser, M. Martin, J. Bridge, S. Faidi, M. Waligora, Marvin Hsiao, Sitara Sharma, Ajith Kumar Sankarankutty, J. Mckee, J. Mckee, J. Mckee, Carolyn Snider, J. Szpakowski, R. Brown, Shishir K. Shah, Maria Y. Shiu, M. Chen, Nathaniel Bell, Floyd Besserer, Nathaniel Bell, Marc Trudeau, M. Alhabboubi, João Rezende-Neto, S. Rizoli, Annabella. P. Hill, Bellal Joseph, B. A. Lawless, X. Jiao, Anargyros Xenocostas, T. Rui, N. Parry, David K. Driman, C. Martin, Tony Stewart, Joanna C. Walsh, N. Parry, Neil Merritt, Eric A. Elster, Homer Tien, Leah Phillips, Ioana Bratu, Bartolomeu Antonio Nascimento, Rafaela Rocha Pinto, Jeannie Callum, Homer Tien, S. Rizoli, Janet Legge McMullan, R. McGlasson, N.N. Mahomed, John Flannery, Ciddi Bir, Frank Baillie, Angela Coates, Sawsan Mohammad Asiri, P. Foster, Frank Baillie, M. Bhandari, Leah Phillips, Ioana Bratu, Nadine Schuurman, Lisa Oliver, A. Nathens, Arjang Yazdani, M. Alhabboubi, Etienne St. Louis, Xianming Tan, Paola Fata, Dan Deckelbaum, Talat Chughtai, Tarek Razek, Kosar Khwaja, Etienne St. Louis, M. Alhabboubi, Xianming Tan, Paola Fata, Dan Deckelbaum, Talat Chughtai, Tarek Razek, Kosar Khwaja, Mamoru Takada, Makoto Sawano, Hiroshi Ito, H Tsutsumi, Alanna Keenan, Melissa Waggott, Blaine Hoshizaki, Susan Brien, Michael D. Gilchrist, Jeffrey E. Janis, Herb A. Phelan, J. Minei, Maria Santana, Henry T. Stelfox, Victoria McCredie, Elizabeth Leung, G. Garcia, S. Rizoli, A. Nathens, E. Dixon, Dan Niven, Andrew W. Kirkpatrick, David V. Feliciano, Scott D’Amours, Chad G. Ball, Najma Ahmed, H. Izadi, Amanda McFarlan, A. Nathens, Katerina Pavenski, A. Nathens, J. Bridge, John M. Tallon, W. Robert Leeper, Kelly Vogt, Tony Stewart, Daryl Gray, N. Parry, A Ameer, M. Alhabboubi, S. Alzaid, Dan Deckelbaum, Paola Fata, Kosar Khwaja, Tarek Razek, Dan Deckelbaum, L. Drudi, Kerianne Boulva, Nathalie Rodrigue, Kosar Khwaja, Talat Chughtai, Paola Fata, Tarek Razek, S. Rizoli, Paulo Roberto Lima Carreiro, Thiago de Assis Lisboa, Philippe C Winter, Emanuel Barbosa Ribeiro, J. Cunha-Melo, Maria Eduarda Soares ANDRADE, D. Zygun, Jan Grendar, Chad G. Ball, Helen Robertson, J.-F. Ouellet, Michael L. Cheatham, Andrew W. Kirkpatrick, Chad G. Ball, J.-F. Ouellet, Paul B. McBeth, Andrew W. Kirkpatrick, E. Dixon, Philip R. Groff, K. Inaba, Obi Okoye, Jason Pasley, D Demetriades, Fayez Al-Harthi, Adam Cheng, Alykhan Lalani, Angelo Mikrogianakis, S. Cayne, Dafna Knittel-Keren, Manuel Gómez, Henry T. Stelfox, AF Turgeon, Jean Lapointe, G Bourgeois, Clara Karton, Philippe Rousseau, Blaine Hoshizaki, Henry T. Stelfox, AF Turgeon, G Bourgeois, Jean Lapointe, Henry T. Stelfox, AF Turgeon, G Bourgeois, Jean Lapointe, Philippe Rousseau, Bya Braga, Rodrigo Moreira Faleiro, M. Magaldi, Gabriela Pontes Cardoso, W. Lozada, Letícia Matos Duarte, S. Rizoli, Chad G. Ball, Elizabeth Oddone-Paolucci, Christoher Doig, John B. Kortbeek, Manuel Gómez, J. Fish, Lopa Leach, Pittavat Leelapattana, Jennifer C. Fleming, Christopher S. Bailey, Brodie Nolan, C. DeMestral, Amanda McFarlan, R. A. Zakirova, Avery B. Nathens, J. Dabbs, D. Duff, Alicja Michalak, Lillian Mitchell, A. Nathens, M. Singh, Jane Topolovec-Vranic, Dawn Tymianski, L Yetman, S. Canzian, Iain MacPhail, Lisa Constable, Rardi van Heest, A. Tam, Priya Mahadevan, D. Kim, Varun Bansal, G Casola, Raúl Coimbra, C. Gladwin, Mahesh C. Misra, Shrawan Kumar, Sashi K. Gautam, Anne Sorvari, Bronagh Blackwood,
# Erythroopoietin resuscitated with normal saline, Ringer’s lactate and 7.5% hypertonic saline reduces small intestine injury in a hemorrhagic shock and resuscitation rat model. {#article-title-2} Bacterial translocation (BT) from the gut can develop and persist after short periods of hemorrhagic
Canadian Medical Association