Valentı́n Fuster, Lars Rydén, David S. Cannom, Harry J.G.M. Crijns, Anne B. Curtis, Kenneth A. Ellenbogen, Jonathan L. Halperin, Jean‐Yves Le Heuzey, G. Neal Kay, James E. Lowe, Sandra Olsson, Eric N. Prystowsky, Juan Tamargo, Samuel Wann, Sidney C. Smith, Alice K. Jacobs, Cynthia D. Adams, Jeffery L. Anderson, Elliott M. Antman, Jonathan L. Halperin, Sharon A. Hunt, Rick A. Nishimura, Joseph P. Ornato, Richard L. Page, Bárbara Riegel, Silvia G. Priori, Jean‐Jacques Blanc, Andrzej Budaj, A. John Camm, Verónica Dean, Jaap W. Deckers, Catherine Despres, Kenneth Dickstein, John Lekakis, Keith McGregor, Marco Metra, João Morais, A. Osterspey, Juan Tamargo, José Luis Zamorano,
... Keith McGregor, PhD, France, Marco Metra, MD, Italy, Joao Morais, MD, FESC, Portugal, Ady Osterspey, MD, Germany, Juan ... LekakisJohn Lekakis , Keith McGregorKeith McGregor , Marco MetraMarco Metra , Joao MoraisJoao Morais , Ady OsterspeyAdy Osterspey , Juan Luis TamargoJuan Luis Tamargo ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2006 - Lippincott Williams & Wilkins | Circulation
Valentı́n Fuster, Lars Rydén, David S. Cannom, Harry J.G.M. Crijns, Anne B. Curtis, Kenneth A. Ellenbogen, Jonathan L. Halperin, Jean-Yves Le Heuzey, G. Neal Kay, James E. Lowe, Sandra Olsson, Eric N. Prystowsky, Juan Tamargo, Samuel Wann, Sidney C. Smith, Alice K. Jacobs, Cynthia D. Adams, Jeffery L. Anderson, Elliott M. Antman, Jonathan L. Halperin, Sharon A. Hunt, Rick A. Nishimura, Joseph P. Ornato, Richard L. Page, Bárbara Riegel, Silvia G. Priori, Jean‐Jacques Blanc, Andrzej Budaj, A. John Camm, Verónica Dean, Jaap W. Deckers, Catherine Despres, Kenneth Dickstein, John Lekakis, Keith McGregor, Marco Metra, João Morais, A. Osterspey, Juan Tamargo, José Luis Zamorano,
... Keith McGregor, PhD, France, Marco Metra, MD, Italy, Joao Morais, MD, FESC, Portugal, Ady Osterspey, MD, Germany, Juan ... Metra Search for more papers by this author , Joao MoraisJoao Morais Search for more papers by this author , Ady ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2006 - Lippincott Williams & Wilkins | Circulation
Produção Nacional
Revisado por pares
Vanderley José Pereira, João Paulo Arantes Rodrigues da Cunha, Tâmara Prado de Morais, João Paulo Ribeiro de Oliveira, João Batista de Morais,
What are the molecular properties of agricultural chemicals, how do they function and why should they be studied?How do they affect the agroecosystem and how are they linked to application technologies?These questions arise due to the lack of information in the literature about this issue and form the basis of the current review.In general, a better understanding of the physical-chemical characteristics of agricultural chemicals makes it possible to improve their efficiency of application, consequently ...
Tópico(s): Weed Control and Herbicide Applications
2016 - UNIVERSIDADE FEDERAL DE UBERLÂNDIA | Bioscience Journal
Maria do Céu Almeida, Maria João Telhado, Marco Morais, João Barreiro, Ruth Gelehrter da Costa Lopes,
The effects of climate dynamics on urban areas involve the aggravation of existing conditions and the potential for emergence of new hazards or risk factors. Floods are recognized as a leading source of consequences to society, including disruption of critical functions in urban areas, and to the environment. Consideration of the interplay between services providers ensuring urban functions is essential to deal with climate dynamics and associated risks. Assessment of resilience to multiple hazards ...
Tópico(s): Disaster Management and Resilience
2020 - Multidisciplinary Digital Publishing Institute | Sustainability
Pedro Figueiredo, Júlio A. Costa, Michele Lastella, João Sílvio Dantas de Morais, João Brito,
This study aimed to describe habitual sleep and nocturnal cardiac autonomic activity (CAA), and their relationship with training/match load in male youth soccer players during an international tournament. Eighteen elite male youth soccer players (aged 14.8 ± 0.3 years; mean ± SD) participated in the study. Sleep indices were measured using wrist actigraphy, and heart rate (HR) monitors were used to measure CAA during night-sleep throughout 5 consecutive days. Training and match loads were characterized ...
Tópico(s): Cardiovascular and exercise physiology
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Gregory Y.H. Lip, Piotr Ponikowski, Felicita Andreotti, Stefan D. Anker, Gerasimos Filippatos, Shunichi Homma, João Morais, Patrick Pullicino, Lars Hvilsted Rasmussen, Francisco Marı́n, Deirdre A. Lane, Gregory Y.H. Lip, Piotr Ponikowski, Felicita Andreotti, Stefan D. Anker, Gerasimos Filippatos, Shunichi Homma, João Morais, Patrick Pullicino, Lars Hvilsted Rasmussen, Francisco Marı́n, Deirdre A. Lane, John J.V. McMurray, Arno W. Hoes, Jurriën M. ten Berg, Raffaele De Caterina, Steen Dalby Kristensen, Uwe Zeymer,
Chronic heart failure (HF) with either reduced or preserved ejection fraction is common and remains an extremely serious disorder with a high mortality and morbidity. Many complications related to HF can be related to thrombosis. Epidemiological and pathophysiological data also link HF to an increased risk of thrombosis, leading to the clinical consequences of sudden death, stroke, systemic thrombo‐embolism, and/or venous thrombo‐embolism. This consensus document of the Heart Failure Association ( ...
Tópico(s): Cardiac Arrhythmias and Treatments
2012 - Elsevier BV | European Journal of Heart Failure
Markku S. Nieminen, Michael Böhm, Martín Cowie, Helmut Drexler, Gerasimos S Filippatos, Guillaume Jondeau, Yonathan Hasin, José Lopez-Sendon, Alexandre Mebazaa, Marco Metra, Andrew Rhodes, Karl Swedberg, Silvia G. Priori, María Ángeles Alonso García, Jean‐Jacques Blanc, Andrzej Budaj, Martín Cowie, Verónica Dean, Jaap W. Deckers, Enrique Fernández Burgos, John Lekakis, Bertil Lindahl, Gianfranco Mazzotta, João Morais, Ali̇ Oto, Otto A. Smiseth, María Ángeles Alonso García, Kenneth Dickstein, Aníbal Albuquerque, Pedro Conthe, María G. Crespo‐Leiro, Roberto Ferrari, Ferenc Folláth, Antonello Gavazzi, Uwe Janssens, Michel Komajda, João Morais, Rui P. Moreno, Mervyn Singer, S. C. Singh, Michał Tendera, Kristian Thygesen,
à Use of Class III is discouraged by the ESC. Levels of EvidenceLevel of Evidence A Data derived from multiple randomized clinical trials or meta-analyses Level of Evidence B Data derived from a single randomized clinical trial or large nonrandomized studies Level of Evidence C Consensus of opinion of the experts and/or small studies; retrospective studies and registriesFigure 1 Clinical classification of the mode of heart failure (Forrester classification).H I-IV refers to haemodynamic severity, ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2005 - Oxford University Press | European Heart Journal
Kristian Thygesen, Joseph S. Alpert, Harvey D. White,
... Czech Republic), José Luis Zamorano (Spain) DOCUMENT REVIEWERS Joao Morais, Review Coordinator (Portugal), Sorin Brener (USA), Robert Harrington ( ... papers by this author and on behalf of Joao Morais, Review Coordinator (Portugal), Sorin Brener (USA), Robert Harrington ( ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2007 - Lippincott Williams & Wilkins | Circulation
Gregory G. Schwartz, Michael Szarek, Vera A. Bittner, Rafael Díaz, Shaun G. Goodman, J. Wouter Jukema, Ulf Landmesser, Patricio López‐Jaramillo, Garen Manvelian, Robert Pordy, Michel Scemama, Peter Sinnaeve, Harvey D. White, Philippe Gabríel Steg, Gregory G. Schwartz, Philippe Steg, Deepak L. Bhatt, Vera A. Bittner, Rafael Diaz, Shaun G. Goodman, Robert A. Harrington, J. Wouter Jukema, Michael Szarek, Harvey D. White, Andreas M. Zeiher, Pierluigi Tricoci, Matthew T. Roe, Kenneth W. Mahaffey, Jay M. Edelberg, Corinne Hanotin, Guillaume Lecorps, Angèle Moryusef, Robert Pordy, William J. Sasiela, Jean‐François Tamby, Rafael Diaz, Philip E. Aylward, Heinz Drexel, Peter Sinnaeve, Mirza Dilic, Renato D. Lopes, Nina Gotcheva, Shaun G. Goodman, Juan-Carlos Prieto, Yong Huo, Patricio López‐Jaramillo, Ivan Pećin, Zeljko Reiner, Petr Ošťádal, Steen Hvitfeldt Poulsen, Margus Viigimaa, Markku S. Nieminen, Nicolas Danchin, Vakhtang Chumburidze, Nikolaus Marx, Evangelos Liberopoulos, Pablo Carlos Montenegro Valdovinos, Hung-Fat Tse, Róbert Gábor Kiss, Denis Xavier, Doron Zahger, Marco Valgimigli, Takeshi Kimura, Hyo Soo Kim, Sang-Hyun Kim, Andrejs Ērglis, Aleksandras Laucevičius, Sasko Kedev, Khalid Yusoff, Gabriel Arturo Ramos López, Marco Alings, Harvey D. White, Sigrun Halvorsen, Roger M. Correa Flores, Rody G. Sy, Andrzej Budaj, Joao Morais, Maria Dorobantu, Yuri Karpov, Arsen D. Ristic, Terrance Chua, Jan Murin, Zlatko Fras, Anthony J. Dalby, José Tuñón, H. Asita de Silva, Emil Hagström, Ulf Landmesser, Christian Müller, Chern‐En Chiang, Piyamitr Sritara, Sema Güneri, Alexander Parkhomenko, Kausik K. Ray, Patrick M. Moriarty, Matthew T. Roe, Robert A. Vogel, Bernard Chaitman, Sheryl F. Kelsey, Anders Olsson, Jean‐Lucien Rouleau, Maarten L. Simoons, Karen P. Alexander, Chiara Meloni, Robert Rosenson, Eric J.G. Sijbrands, Pierluigi Tricoci, John H. Alexander, Luciana Armaganijan, Akshay Bagai, Maria Cecilia Bahit, James M. Brennan, Shaun Clifton, Adam D. DeVore, Shalonda Deloatch, Sheila Dickey, Keith Dombrowski, Grégory Ducrocq, Zubin J. Eapen, Patricia Endsley, Arleen Eppinger, Robert W. Harrison, Connie Ng Hess, Mark A. Hlatky, J. Dedrick Jordan, Joshua W. Knowles, Brad J. Kolls, David F. Kong, Sergio Leonardi, Linda Lillis, Renato D. Lopes, David J. Maron, Kenneth W. Mahaffey, Jill Marcus, Robin Mathews, Rajendra H. Mehta, Robert J. Mentz, Humberto Graner Moreira, Chetan B. Patel, Sabrina Bernardez Pereira, Lynn Perkins, Thomas J. Povsic, Etienne Puymirat, Matthew T. Roe, W. Schuyler Jones, Bimal R. Shah, Matthew W. Sherwood, Kenya Stringfellow, Darin Sujjavanich, Mustafa Toma, Charlene Trotter, Sean F.P. van Diepen, Matthew D. Wilson, Andrew Tze-Kay Yan, Lilia Schiavi, Marcelo Garrido, Andrés F. Alvarisqueta, Sonia A. Sassone, Anselmo P. Bordonava, Alberto Enrique Alves de Lima, Jorge M. Schmidberg, Ernesto Duronto, Orlando C. Caruso, Leonardo P. Novaretto, Miguel Angel Hominal, Oscar Montaña, Alberto Caccavo, Oscar A. Gomez Vilamajo, Alberto J. Lorenzatti, Luis Cartasegna, Gustavo A. Paterlini, Ignacio MacKinnon, Guillermo D. Caime, Philippe Gabríel Steg, Oscar Salomone, Oscar R. Codutti, Horacio O. Jure, Julio O.E. Bono, Adrian D. Hrabar, Julio Vallejos, Rodolfo A. Ahuad Guerrero, Federico Novoa, Cristian A. Patocchi, Cesar Javier Zaidman, Maria E. Giuliano, Ricardo D. Dran, Marisa L. Vico, Gabriela S. Carnero, Pablo N. Guzman, Juan C. Medrano Allende, Daniela F. Garcia Brasca, Miguel H Bustamante Labarta, S Nani, Eduardo D.S. Blumberg, Hugo Colombo, Alberto Liberman, Victorino Fuentealba, Héctor Luciardi, Gabriel Waisman, Mario A Berli, Ruben O Garcia Duran, Horacio G Cestari, Hugo A Luquez, Jorge A Giordano, Silvia S Saavedra, Gerardo Zapata, Osvaldo Costamagna, Susana C. Llois, J. Waites, Nicholas Collins, Allan Soward, Philip E. Aylward, Chris L.S. Hii, Philip E. Aylward, James Shaw, Margaret Arstall, John Horowitz, Daniel Ninio, James Frederick Rogers, David Colquhoun, Romulo E Oqueli Flores, Philip Roberts‐Thomson, O. Raffel, Sam J. Lehman, Constantine Aroney, Steven Coverdale, P. Garrahy, Gregory Starmer, Mark Sader, Patrick A. Carroll, Ronald Dick, Robert Zweiker, Uta Hoppe, Heinz Drexel, Kurt Huber, Rudolf Berger, Georg Delle-Karth, Bernhard Frey, Dirk Faes, Kurt Hermans, B. Pirenne, Attilio Leone, Etienne Hoffer, Peter Sinnaeve, Mathias C.M. Vrolix, Luc De Wolf, Bart Wollaert, Marc Castadot, Karl Dujardin, Christophe Beauloye, Geert Vervoort, Harry Striekwold, Carl Convens, John Roosen, Emanuele Barbato, Marc Claeys, Frank Cools, Ibrahim Terzić, Fahir Baraković, Zlatko Midzic, Belma Pojskic, Emir Fazlibegovic, Mirza Dilic, Azra Durak-Nalbantic, Mehmed Kulić, Dusko Vulic, Adis Muslibegovic, Boris Goronja, Gilmar Reis, Luciano Sousa, José Carlos Nicolau, Flavio E Giorgeto, Ricardo Pereira Silva, Lilia Nigro Maia, Rafael Rech, Paulo R.F. Rossi, Maria José AG Cerqueira, Norberto Duda, Renato Kalil, Adrian Kormann, José Antonio M. Abrantes, Pedro Pimentel Filho, Ana Priscila Soggia, Mayler O.N. de Santos, Fernando Neuenschwander, Luiz Carlos Bodanese, Yorghos L Michalaros, Freddy G. Eliaschewitz, Maria H Vidotti, Paulo Leães, Roberto V. Botelho, Sérgio Kaiser, Euler Roberto Fernandes Manenti, Dalton B. Precoma, José Carlos Moura Jorge, Pedro Silva,
Guidelines recommend nonstatin lipid-lowering agents in patients at very high risk for major adverse cardiovascular events (MACE) if low-density lipoprotein cholesterol (LDL-C) remains ≥70 mg/dL on maximum tolerated statin treatment. It is uncertain if this approach benefits patients with LDL-C near 70 mg/dL. Lipoprotein(a) levels may influence residual risk. In a post hoc analysis of the ODYSSEY Outcomes (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) ...
Elsevier BV
Cristina Cavaco, João Morais Mourato, João Pedro Costa, João Ferrão,
Over the last decade, soft planning has become an increasingly visible concept in planning literature. Since the term soft spaces was firstly coined, soft planning has been used to describe a growing number of practices that occur at the margins of statutory planning systems. However, as soft planning-related literature proliferates, so does the diversity of approaches and planning practices it encompasses. Such diversity fuels long-standing questions about what can or cannot be considered as soft ...
Tópico(s): Regional resilience and development
2022 - SAGE Publishing | Planning Theory
Emil Hagström, Philippe Gabríel Steg, Michael Szarek, Deepak L. Bhatt, Vera Bittner, Nicolas Danchin, Rafael Díaz, Shaun G. Goodman, Robert A. Harrington, J. Wouter Jukema, Evangelos Liberopoulos, Nikolaus Marx, Jennifer McGinniss, Garen Manvelian, Robert Pordy, Michel Scemama, Harvey D. White, Andreas M. Zeiher, Gregory G. Schwartz, Gregory G. Schwartz, Deepak L. Bhatt, Vera Bittner, Rafael Díaz, Shaun G. Goodman, Robert A. Harrington, J. Wouter Jukema, Michael Szarek, Harvey D. White, Andreas M. Zeiher, Pierluigi Tricoci, Matthew T. Roe, Kenneth W. Mahaffey, Jay M. Edelberg, Corinne Hanotin, Guillaume Lecorps, Angèle Moryusef, Robert Pordy, William J. Sasiela, Jean‐François Tamby, Rafael Díaz, Philip E Aylward, Heinz Drexel, Peter Sinnaeve, Mirza Dilić, Renato D. Lópes, Nina N Gotcheva, Shaun G. Goodman, Juan Carlos Prieto, Huo Yong, Patricio López‐Jaramillo, Ivan Pećin, Zeljko Reiner, Petr Ostadal, Steen Hvitfeldt Poulsen, Margus Viigimaa, Markku S Nieminen, Nicolas Danchin, Vakhtang Chumburidze, Nikolaus Marx, Evangelos Liberopoulos, Pablo Carlos, Montenegro Valdovinos, Hung‐Fat Tse, Róbert Gábor Kiss, Denis Xavier, Doron Zahger, Marco Valgimigli, Takeshi Kimura, Hyo-Soo Kim, Sang‐Hyun Kim, Andrejs Ērglis, Aleksandras Laucevičius, Saško Kedev, Khalid Yusoff, Gabriel Arturo Ramos López, Marco Alings, Harvey D. White, Sigrun Halvorsen, Roger M Correa Flores, Rody G. Sy, Andrzej Budaj, João Morais, Maria Dorobantu, Yuri Karpov, Arsen Ristić, Terrance Chua, Ján Murín, Zlatko Fras, Anthony J. Dalby, José Tuñón, H. Asita de Silva, Emil Hagström, Ulf Landmesser, Christian Müller, Chern‐En Chiang, Piyamitr Sritara, Sema Güneri, Alexander Parkhomenko, Kausik K. Ray, Patrick M. Moriarty, Matthew T. Roe, Robert A. Vogel, Bernard Chaitman, Sheryl F. Kelsey, Anders Olsson, Jean-Lucien Rouleau, Maarten L. Simoons, Karen Alexander, Chiara Meloni, Robert Rosenson, Eric J.G. Sijbrands, Pierluigi Tricoci, John H. Alexander, Luciana Armaganijan, Akshay Bagai, Maria Cecilia Bahit, J. Matthew Brennan, Shaun Clifton, Adam D. DeVore, Shalonda Deloatch, Sheila Dickey, Keith Dombrowski, Grégory Ducrocq, Zubin J. Eapen, Patricia Endsley, Arleen Eppinger, Robert W. Harrison, Connie Ng Hess, Mark A. Hlatky, J. Dedrick Jordan, Joshua W. Knowles, Brad J. Kolls, David F. Kong, Sergio Leonardi, Linda Lillis, Renato D. Lópes, David J. Maron, Kenneth W. Mahaffey, Jill Marcus, Robin Mathews, Rajendra H. Mehta, Robert J. Mentz, Humberto Graner Moreira, Chetan B. Patel, Sabrina Bernardez Pereira, Lynn Perkins, Thomas J. Povsic, Etienne Puymirat, Matthew T. Roe, W. Schuyler Jones, Bimal R. Shah, Matthew W. Sherwood, Kenya Stringfellow, Darin Sujjavanich, Mustafa Toma, Charlene Trotter, Sean F.P. van Diepen, Matthew D. Wilson, Andrew T. Yan, Lilia Schiavi, Marcelo Garrido, Andrés F. Alvarisqueta, Sonia A Sassone, Anselmo P Bordonava, Alberto E Alves De Lima, Jorge M. Schmidberg, Ernesto A Duronto, Orlando C. Caruso, Leonardo P Novaretto, Miguel Angel Hominal, Oscar Montaña, Alberto Caccavo, Oscar A. Gomez Vilamajo, Alberto J. Lorenzatti, Luis R Cartasegna, Gustavo A. Paterlini, Ignacio J Mackinnon, Guillermo D. Caime, Philippe Gabríel Steg, Oscar Salomone, Oscar R. Codutti, Horacio O. Jure, Julio Bono, Adrian D. Hrabar, Julio Vallejos, Rodolfo A Ahuad Guerrero, Federico Novoa, Cristian A. Patocchi, Cesar Javier Zaidman, María Elena Giuliano, Ricardo D. Dran, Marisa L. Vico, Gabriela S. Carnero, Pablo N. Guzman, Juan C. Medrano Allende, Daniela F Garcia Brasca, Miguel H Bustamante Labarta, Sebastian Nani, Eduardo DS Blumberg, Hugo Colombo, Alberto Liberman, Victorino Fuentealba, Héctor Luciardi, Gabriel Waisman, Mario A Berli, Ruben O Garcia Duran, Horacio G Cestari, Hugo A Luquez, Jorge A Giordano, Silvia S Saavedra, Gerardo Zapata, Osvaldo Costamagna, Susana C. Llois, J. Waites, Nicholas Collins, Allan Soward, Philip E Aylward, Chris LS Hii, Philip E Aylward, James Shaw, Margaret Arstall, John D. Horowitz, Daniel Ninio, James Frederick Rogers, David Colquhoun, Romulo E Oqueli Flores, Philip Roberts-Thomson, Owen Raffel, Sam J. Lehman, Constantine Aroney, Steven Coverdale, P. Garrahy, Gregory Starmer, Mark Sader, Patrick A. Carroll, Ronald Dick, Robert Zweiker, Uta Hoppe, Heinz Drexel, Kurt Huber, Rudolf Berger, Georg Delle-Karth, Bernhard Frey, Franz Weidinger, Dirk Faes, Kurt Hermans, B. Pirenne, Attilio Leone, E Hoffer, Peter Sinnaeve, Mathias Vrolix, Luc De Wolf, Bart Wollaert, Marc Castadot, Karl Dujardin, Christophe Beauloye, Geert Vervoort, Harry Striekwold, Carl Convens, John Roosen, Emanuele Barbato, Marc J. Claeys, Frank Cools, Ibrahim Terzić, Fahir Barakovic, Zlatko Midzic, Belma Pojskić, Emir Fazlibegovic, Mirza Dilić, Azra Durak-Nalbantić, Mehmed Kulić, Dusko Vulic, Adis Muslibegovic, Boris Goronja, Gilmar Reis, Luciano Fernandes Sousa, José Carlos Nicolau, Flavio E Giorgeto, Ricardo Pereira Silva, Lília Nigro Maia, Rafael Rech, Paulo RF Rossi, Maria José AG Cerqueira, Norberto Duda, Renato Kalil, Adrian Kormann, José Antonio M Abrantes, Pedro Pimentel Filho, Ana Priscila Soggia, Mayler ON de Santos, Fernando Neuenschwander, Luiz Carlos Bodanese, Yorghos L Michalaros, Freddy G. Eliaschewitz, Maria H Vidotti, Paulo Leães,
Background: Apolipoprotein B (apoB) provides an integrated measure of atherogenic risk. Whether apoB levels and apoB lowering hold incremental predictive information on residual risk after acute coronary syndrome beyond that provided by low-density lipoprotein cholesterol is uncertain. Methods: The ODYSSEY OUTCOMES trial (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) compared the proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab ...
Lippincott Williams & Wilkins
Jonas F. Schlagintweit, Christian Jakob, Nicola L. Wilke, Marie Ahrweiler, Corazon Frias, Jerico Frias, Marcel König, Eva‐Maria H. J. Esslinger, Fernanda Marques, João Franco Machado, Robert M. Reich, Tânia S. Morais, João D. G. Correia, Aram Prokop, Fritz E. Kühn,
The synthesis and antiproliferative activity of Mes- and iPr-substituted gold(I) bis(1,2,3-triazol-5-ylidene) complexes in various cancer cell lines are reported, showing nanomolar IC50 values of 50 nM (lymphoma cells) and 500 nM (leukemia cells), respectively (Mes < iPr). The compounds exclusively induce apoptosis (50 nM to 5 μM) instead of necrosis in common malignant blood cells (leukemia cells) and do not affect non-malignant leucocytes. Remarkably, the complexes not only overcome resistances against ...
Tópico(s): Metal complexes synthesis and properties
2021 - American Chemical Society | Journal of Medicinal Chemistry
Produção Nacional
Revisado por pares
Ana A. D. Leal, Joel Faintuch, Álvaro A.C. Morais, Joao A. B. Noe, Diandria M. Bertollo, Rafael C. Morais, Danielle Cabrini,
Abstract Objectives: Questions about reliability of bioimpedance analysis (BIA) in morbidly obese subjects have curtailed its use in this setting, but metabolic implications might reignite the debate. In a prospective study, it was aimed to analyze anthropometric and clinical associations. Methods: Bariatric candidates ( n = 94) with or without metabolic syndrome were consecutively investigated. Age was 34.9 ± 10.4 years (68.1% females), and BMI was 40.8 ± 4.6 kg m −2 . Methods included single‐frequency BIA, ...
Tópico(s): Electrical and Bioimpedance Tomography
2011 - Wiley | American Journal of Human Biology
Produção Nacional
Revisado por pares
Selene Maia de Morais, João Tavares Calixto Júnior, Luciana Maria Ribeiro, Halisson Araújo de Sousa, A.A.S. Silva, Fernando G. Figueiredo, Ednardo F. F. MATIAS, Aline Augusti Boligon, Margareth Linde Athayde, Maria Flaviana Bezerra Morais‐Braga, Henrique Douglas Melo Coutinho,
Tea from the bark and leaves of Guazuma ulmifolia Lam. (Malvaceae) are used in several countries in South and Central America in cases of gastrointestinal and skin problems, among other diseases. The aim of this study was to characterize the chemical composition and its antioxidant, anticholinesterase and antifungal activity to correlate these with the popular use of this plant. The antioxidant activity was evaluated by DPPH method and the anticholinesterase action by inhibiting the acetylcholinesterase ...
Tópico(s): Phytochemicals and Antioxidant Activities
2016 - Elsevier BV | South African Journal of Botany
Produção Nacional
Leonardo Fiúsa de Morais, João Carlos de Carvalho Almeida, Bruno Borges Deminicis, Fábio Teixeira de Pádua, Mirton José Frota Morenz, João Batista Rodrigues de Abreu, Raphael Pavesi Araújo, Delci D. de Nepomuceno,
The aim of this study was to evaluate methods for breaking dormancy of seeds Neonotonia wightii (perennial soybean), Macrotiloma axilare (archer), Pueraria phaseoloides (tropical kudzu), Calopogonium mucunoides (calopo), which were subjected to the following treatments for physical breaks and physiological dormancy: 1) control; 2) scarification with sandpaper; 3) immersion in H2SO4 98% for five minutes and subsequent washing in water; 4) preheating at 60°C for 150 minutes in an air circulating oven; ...
Tópico(s): Soybean genetics and cultivation
2014 - Scientific Research Publishing | American Journal of Plant Sciences
António Mateus‐Pinheiro, PatrÃcia PatrÃcio, Nuno Dinis Alves, A.R. Machado-Santos, Mónica Morais, João M. Bessa, Nuno Sousa, Luísa Pinto,
Measuring anhedonic behavior in rodents is a challenging task as current methods display only moderate sensitivity to detect anhedonic phenotype and, consequently, results from different labs are frequently incongruent. Herein we present a newly-developed test, the Sweet Drive Test (SDT), which integrates food preference measurement in a non-aversive environment, with ultrasonic vocalizations (USVs) recording. Animals were placed in a soundproofed black arena, under red light illumination, and allowed ...
Tópico(s): Olfactory and Sensory Function Studies
2014 - Frontiers Media | Frontiers in Behavioral Neuroscience
Produção Nacional
Revisado por pares
D.S. Morais, João Coelho, María Pía Ferraz, Pedro S. Gomes, Maria Helena Fernandes, Sooraj Hussain Nandyala, José D. Santos, M.A. Lopes,
A novel bioactive bone substitute with improved osteoblastic performance and effective antibacterial activity was developed, using a completely new approach based on samarium (Sm3+) doped P2O5 glass-reinforced hydroxyapatite composites (GR-HA). The composites were prepared by adding 2.5% (w/w) of the P2O5 glass to 97.5% (w/w) of HA. Four composites were developed, i.e. one non-doped composite, and three Sm3+ doped composites prepared with the P2O5 glass containing 0.5, 1 and 2 (mol%) of Sm2O3. The composites ...
Tópico(s): Dental Implant Techniques and Outcomes
2014 - Royal Society of Chemistry | Journal of Materials Chemistry B
Sandro Queirós, Daniel Barbosa, Brecht Heyde, Pedro Morais, João L. Vilaça, Denis Friboulet, Olivier Bernard, Jan D’hooge,
A novel automatic 3D+time left ventricle (LV) segmentation framework is proposed for cardiac magnetic resonance (CMR) datasets. The proposed framework consists of three conceptual blocks to delineate both endo and epicardial contours throughout the cardiac cycle: (1) an automatic 2D mid-ventricular initialization and segmentation; (2) an automatic stack initialization followed by a 3D segmentation at the end-diastolic phase; and (3) a tracking procedure. Hereto, we propose to adapt the recent B-spline ...
Tópico(s): Advanced Neural Network Applications
2014 - Elsevier BV | Medical Image Analysis
Mark D. Opal, S C Klenotich, Mónica Morais, João M. Bessa, Jessica A. Van Winkle, Demetrios Doukas, Leslie M. Kay, Nuno Sousa, S M Dulawa,
Current antidepressants must be administered for several weeks to produce therapeutic effects. We show that selective serotonin 2C (5-HT2C) antagonists exert antidepressant actions with a faster-onset (5 days) than that of current antidepressants (14 days) in mice. Subchronic (5 days) treatment with 5-HT2C antagonists induced antidepressant behavioral effects in the chronic forced swim test (cFST), chronic mild stress (CMS) paradigm and olfactory bulbectomy paradigm. This treatment regimen also induced ...
Tópico(s): Neuroscience and Neuropharmacology Research
2013 - Springer Nature | Molecular Psychiatry
Pedro Figueiredo, Pedro Morais, João Paulo Vilas‐Boas, Ricardo J. Fernandes,
Tópico(s): Cardiovascular and exercise physiology
2013 - Springer Science+Business Media | European Journal of Applied Physiology
Christian Fernandéz, Cláudia Morais, João Rocha, Marek Pruski,
Tópico(s): Zeolite Catalysis and Synthesis
2002 - Elsevier BV | Solid State Nuclear Magnetic Resonance
Duarte Ananias, José P. Rainho, Artur Ferreira, Marta Lopes, Cláudia Morais, João Rocha, Luís D. Carlos,
The hydrothermal synthesis in mild conditions, and the structural characterizations and luminescence properties, of yttrium and erbium silicates Na3MSi3O9, M = Y(III) and Er(III), has been reported. Na3ErSi3O9 is a new infrared emitter with an emission spectrum displaying a broad visible band (300−700 nm) and a series of narrow infrared intra-4f11 4I13/2 → 4I15/2 lines. The number of Stark components detected (ca. 32) indicates the presence of four optically active environments, in accord with the structural ...
Tópico(s): Solid-state spectroscopy and crystallography
2002 - American Chemical Society | Chemistry of Materials
J.L. Jordá, Lynne B. McCusker, Christian Baerlocher, Cláudia Morais, João Rocha, Christian Fernandéz, Cristina Borges, João P. Lourenço, M.F. Ribeiro, Z. Gabélica,
A combination of advanced powder diffraction and NMR techniques have allowed the structure of the novel microporous aluminophosphate IST-1 (|(CH3NH2)4(CH3NH3+)4(OH−)4|[Al12P12O48]) to be elucidated. The framework structure was determined in the non-centrosymmetric space group Pca21 (a=9.61523(1) Å, b=8.67024(1) Å, c=16.21957(2) Å) from high-resolution synchrotron powder diffraction data using the program FOCUS. Extra framework species were then located on difference electron density maps. A hydroxyl ...
Tópico(s): Metal-Organic Frameworks: Synthesis and Applications
2003 - Elsevier BV | Microporous and Mesoporous Materials
Artur Ferreira, Duarte Ananias, Luís D. Carlos, Cláudia Morais, João Rocha,
The synthesis and structural characterization of microporous lanthanide silicates (Na(1.08)K(0.5)Ln(1.14)Si(3)O(8.5).1.78H(2)O, Ln = Eu, Tb, Sm, Ce) are reported. The structure of these solids is closely related with the structure of hydrated calcium silicate minerals known as tobermorites and was solved by powder X-ray diffraction ab initio (direct) methods and further characterized by chemical analysis, thermogravimetry, scanning electron microscopy, (23)Na and (29)Si MAS NMR and luminescence spectroscopy. ...
Tópico(s): Glass properties and applications
2003 - American Chemical Society | Journal of the American Chemical Society
Produção Nacional
Revisado por pares
Ingrid Espejo Carvacho, Maeve B. Mello, Sirlei Siani Moráis, João Luiz Pinto e Silva,
OBJETIVO: Analisar os fatores determinantes do acesso de adolescentes gestantes a serviços de atenção primária à saúde, anterior à ocorrência da gestação. MÉTODOS: Estudo transversal baseado em referencial teórico. O acesso a serviços foi analisado em cinco dimensões: geográfico, econômico, administrativo, psicossocial e de informação. Participaram 200 adolescentes primigestas (10 a 19 anos) atendidas em uma unidade básica de saúde do município de Indaiatuba (SP), em 2003. Um questionário com perguntas ...
Tópico(s): Food Security and Health in Diverse Populations
2008 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Produção Nacional
Revisado por pares
José Guilherme Cecatti, Eloísa P. B. Correa-Silva, Helaine Milanez, Sirlei Siani Moráis, João Paulo Souza,
Tópico(s): Maternal and fetal healthcare
2007 - Springer Science+Business Media | Maternal and Child Health Journal
Maria do Céu Sousa, Joana Morais, João Machado, J. Poiares-da-Silva,
Journal of Eukaryotic MicrobiologyVolume 53, Issue s1 p. S174-S176 Genotyping of Giardia lamblia Human Isolates from Portugal by PCR-RFLP and Sequencing M. C. SOUSA, M. C. SOUSA Centre of Pharmaceutical Studies, Laboratory of Microbiology and Parasitology, Faculty of Pharmacy, University of Coimbra, Coimbra, PortugalSearch for more papers by this authorJ. B. MORAIS, J. B. MORAIS Centre of Pharmaceutical Studies, Laboratory of Microbiology and Parasitology, Faculty of Pharmacy, University of Coimbra, ...
Tópico(s): Amoebic Infections and Treatments
2006 - Wiley | Journal of Eukaryotic Microbiology
Ioannis Pirmettis, Yasushi Arano, Theodoros Tsotakos, Kaoru Okada, Aiko Yamaguchi, Tomoya Uehara, Maurício Morais, João D. G. Correia, Isabel Santos, Manuel A. Martins, S. Pereira, Charalampos Triantis, Patricia Kyprianidou, Maria Pelecanou, Minas Papadopoulos,
The aim of the present study is to synthesize new mannosylated dextran derivative that can be labeled with Tc-99m for potential use in sentinel lymph node detection (SLND). The compound was designed to have a dextran with molecular weight of 10 kDa as a backbone, mannose for binding to mannose receptors of the lymph node and S-derivatized cysteine as a suitable chelator for labeling with [(99m)Tc(H(2)O)(3)(CO)(3)](+) precursor. Reaction of allyl bromide with dextran (MW 11800) yielded the intermediate ...
Tópico(s): Medical Imaging and Pathology Studies
2012 - American Chemical Society | Molecular Pharmaceutics
Tiago Sousa, Hugo Morais, João Soares, Zita Vale,
Energy resource scheduling becomes increasingly important, as the use of distributed resources is intensified and massive gridable vehicle use is envisaged. The present paper proposes a methodology for day-ahead energy resource scheduling for smart grids considering the intensive use of distributed generation and of gridable vehicles, usually referred as Vehicle-to-Grid (V2G). This method considers that the energy resources are managed by a Virtual Power Player (VPP) which established contracts with ...
Tópico(s): Microgrid Control and Optimization
2012 - Elsevier BV | Applied Energy
... https://doi.org/10.1111/mec.13801Paulo de Morais Oliveira Joao, Ferreira Silva Jessica, Santos de Oliveira Bruna, Gomes ...
Tópico(s): Avian ecology and behavior
1993 - University of Chicago Press | The American Naturalist