Produção Nacional
H. R. S. Nazareth, Carlos Alberto Moreira‐Filho, A. J. B. Cunha, João Paulo Botelho Vieira‐Filho, A. M. J. Lengyel, Marta Cunha Lima, John M. Optiz,
Abstract Clinical, cytogenetic, pathologic and histocompatibility‐Y (H‐Y) antigen studies were performed on a phenotypic female with primary amenorrhea and streak gonads. Pathological examination of tissues removed at total hysterectomy and bilateral salpingo‐gonadectomy showed gonadoblastoma and dysgerminoma of left streak. A single F‐body (Y chromosome) was found in buccal smears. Analysis of blood cells and tumor fibroblasts showed a 46, XY chromosome constitution (Q‐banding). The data were consistent ...
Tópico(s): Testicular diseases and treatments
1979 - Wiley | American Journal of Medical Genetics
Produção Nacional
Revisado por pares
José Lailson‐Brito, Paulo R. Dorneles, Cláudio E. Azevedo-Silva, Alexandre de Freitas Azevedo, Lara G. Vidal, R.C. Zanelatto, C.P.C. Lozinski, Antônio Azeredo, Ana Bernadete Lima Fragoso, Haydée A. Cunha, João Paulo Machado Torres, Olaf Malm,
Blubber samples from 33 Guiana dolphins (Sotalia guianensis) from three estuaries (Guanabara, Sepetiba/Ilha Grande and Paranaguá Bays) of Southern and Southeastern Brazil were analyzed for organochlorine compounds (DDTs, PCBs and HCB). The sampled individuals were incidentally captured in gillnet fishery between 1995 and 2005. The concentrations (in ng/g lipids) varied from 652 to 23 555 for SigmaDDT; from 765 to 99 175 for SigmaPCB; and from <4.4 to 156 for HCB. The results have shown that cetaceans ...
Tópico(s): Marine animal studies overview
2009 - Elsevier BV | Environmental Pollution
Catarina Silva, Vitor A. Cunha, João Paulo Barraca, Rui L. Aguiar,
Abstract The advances on recent communication paradigms brings new security and privacy challenges, mainly about personal data collection by smart devices. Resource constrained devices face serious issues to run complex cryptographic algorithms. Trying to evaluate the performance impact of those algorithms in usual and common devices used in smart homes, in this paper we tested the impact of different cryptographic algorithms in low computational devices, typically used in smart devices applied ...
Tópico(s): Bluetooth and Wireless Communication Technologies
2023 - Springer Science+Business Media | Information Systems Frontiers
Rui Pereira, Marco Couto, Francisco Ribeiro, Rui Rua, Jácome Cunha, João Paulo Fernandes, João Saraiva,
This paper compares a large set of programming languages regarding their efficiency, including from an energetic point-of-view. Indeed, we seek to establish and analyze different rankings for programming languages based on their energy efficiency. The goal of being able to rank programming languages based on their energy efficiency is both recent, and certainly deserves further studies. We have taken rigorous and strict solutions to 10 well defined programming problems, expressed in (up to) 27 programming ...
Tópico(s): Smart Grid Energy Management
2021 - Elsevier BV | Science of Computer Programming
Produção Nacional
Revisado por pares
Bruno Carneiro da Cunha, João Paulo Cavalcante,
We conduct an analysis of the quasinormal modes for generic spin perturbations of the Kerr black hole using the isomonodromic method. The strategy consists of solving the Riemann-Hilbert map relating the accessory parameters of the differential equations involved to monodromy properties of the solutions, using the $\ensuremath{\tau}$-function for the Painlev\'e V transcendent. We show excellent accordance of the method with the literature for generic rotation parameter $a<M$. In the extremal limit, ...
Tópico(s): Numerical methods for differential equations
2021 - American Physical Society | Physical review. D/Physical review. D.
Produção Nacional
Revisado por pares
Bruno Carneiro da Cunha, João Paulo Cavalcante,
Quasinormal modes of usual, four dimensional, Kerr black holes are described by certain solutions of a confluent Heun differential equation. In this work, we express these solutions in terms of the connection matrices for a Riemann-Hilbert problem, which was recently solved in terms of the Painlevé V transcendent. We use this formulation to generate the small-frequency expansion for the angular spheroidal harmonic eigenvalue, and derive conditions on the monodromy properties for the radial modes. ...
Tópico(s): Cosmology and Gravitation Theories
2020 - American Physical Society | Physical review. D/Physical review. D.
Produção Nacional
Revisado por pares
Daniel Pires Bitencourt, Lincoln M. Alves, Elisa Shibuya, Irlon de Ângelo da Cunha, João Paulo Estevam de Souza,
Abstract Climate change has caused an increased occurrence of heat waves. As a result of rising temperatures, implications for health and the environment have been more frequently reported. Outdoor labour activities deserve special attention, as is the case with agricultural and construction workers exposed to extreme weather conditions, including intense heat. This paper presents an overview of heat stress conditions in Brazil from 1961 to 2010. It also presents computer‐simulated projections of ...
Tópico(s): Urban Heat Island Mitigation
2020 - Wiley | International Journal of Climatology
Tiago Coito, Joaquim L. Viegas, Miguel S. E. Martins, Mariana Mesquita-Cunha, João Paulo Figueiredo, Susana M. Vieira, João M. C. Sousa,
As the industry continues to pursue the reduction of downtimes and increases in the efficiency of resource usage, data appears as a valuable business asset, empowering intelligent automation solutions. In order to deal with current challenges in acquisition and management of data in industrial settings, this paper proposes a framework for intelligent automation. The traditional automation pyramid does not cope with today's application requirements, as intelligent automation needs to exchange, in ...
Tópico(s): Advanced Manufacturing and Logistics Optimization
2019 - Elsevier BV | IFAC-PapersOnLine
Rui Pereira, Tiago Carção, Marco Couto, Jácome Cunha, João Paulo Fernandes, João Saraiva,
Although hardware is generally seen as the main culprit for a computer’s energy usage, software too has a tremendous impact on the energy spent. Unfortunately, there is still not enough support for software developers so they can make their code more energy-aware. This paper proposes a technique to detect energy inefficient fragments in the source code of a software system. Test cases are executed to obtain energy consumption measurements, and a statistical method, based on spectrum-based fault ...
Tópico(s): Caching and Content Delivery
2019 - Elsevier BV | Journal of Systems and Software
Produção Nacional
Flávio Gomes de Oliveira, Wandrick Hauss de Sousa, Felipe Queiroga Cartaxo, Maria das Graças Gomes Cunha, João Paulo de Farias Ramos, Marcílio Fontes Cézar, Lenice Mendonça de Menezes, A. B. de Oliveira,
SUMMARY This study evaluated the characteristics of carcass and commercial cuts of Santa Ines lambs of different biotypes (traditional and modern) slaughtered at 32 kg and 34 kg. The thirty-six Santa Ines sheep used, of which 18 traditional and 18 modern biotypes were on average 180 days old and weighed 16 kg initially. The animals were kept in individual stalls (0.80 × 1.20 m) until they reached the slaughtering weight. The experimental design was completely randomized, factorial 2×2 (two biotypes x ...
Tópico(s): Meat and Animal Product Quality
2018 - UNIVERSIDADE FEDERAL DA BAHIA | Revista Brasileira de Saúde e Produção Animal
Marco Couto, Tiago Carção, Jácome Cunha, João Paulo Fernandes, João Saraiva,
The use of powerful mobile devices, like smartphones, tablets and laptops, is changing the way programmers develop software. While in the past the primary goal to optimize software was the run time optimization, nowadays there is a growing awareness of the need to reduce energy consumption. This paper presents a technique and a tool to detect anomalous energy consumption in Android applications, and to relate it directly with the source code of the application. We propose a dynamically calibrated ...
Tópico(s): Caching and Content Delivery
2014 - Springer Science+Business Media | Lecture notes in computer science
Jácome Cunha, João Paulo Fernandes, Jorge Mendes, João Saraiva,
This paper proposes and validates a model-driven software engineering technique for spreadsheets. The technique that we envision builds on the embedding of spreadsheet models under a widely used spreadsheet system. This means that we enable the creation and evolution of spreadsheet models under a spreadsheet system. More precisely, we embed ClassSheets, a visual language with a syntax similar to the one offered by common spreadsheets, that was created with the aim of specifying spreadsheets. Our ...
Tópico(s): Green IT and Sustainability
2014 - IEEE Computer Society | IEEE Transactions on Software Engineering
Produção Nacional
Revisado por pares
Larissa Schmauder Teixeira da Cunha, João Paulo Machado Torres, Juan Muñoz-Arnanz, Begoña Jiménez,
This study aimed to investigate the impact of contamination by persistent organic pollutants (POPs) on Brazilian wildlife. The concentrations of certain POPs, including dichlorodiphenyltrichloroethane (DDT) and polychlorinated biphenyls (PCBs), in the eggs of the brown booby (Sula leucogaster) were measured. The eggs were collected from breeding colonies located on three archipelagos (Saint Peter and Saint Paul, Abrolhos and Cagarras Islands) in the Atlantic Ocean, which are located at different distances ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2012 - Elsevier BV | Chemosphere
Jácome Cunha, João Paulo Fernandes, Hugo Ribeiro, João Saraiva,
Spreadsheets are considered to be the most widely used programming language in the world, and reports have shown that 90% of real-world spreadsheets contain errors. In this work, we try to identify spreadsheet smells, a concept adapted from software, which consists of a surface indication that usually corresponds to a deeper problem. Our smells have been integrated in a tool, and were computed for a large spreadsheet repository. Finally, the analysis of the results we obtained led to the refinement ...
Tópico(s): Mobile Crowdsensing and Crowdsourcing
2012 - Springer Science+Business Media | Lecture notes in computer science
Jácome Cunha, João Paulo Fernandes, Jorge Mendes, Hugo Pacheco, João Saraiva,
Spreadsheets play an important role in software organizations. Indeed, in large software organizations, spreadsheets are not only used to define sheets containing data and formulas, but also to collect information from different systems, to adapt data coming from one system to the format required by another, to perform operations to enrich or simplify data, etc. In fact, over time many spreadsheets turn out to be used for storing and processing increasing amounts of data and supporting increasing ...
Tópico(s): Simulation Techniques and Applications
2012 - Springer Science+Business Media | Lecture notes in computer science
Laura Beckwith, Jácome Cunha, João Paulo Fernandes, João Saraiva,
Tópico(s): Statistics Education and Methodologies
2011 - Springer Science+Business Media | Lecture notes in computer science
Produção Nacional
Revisado por pares
A. L. V. L. Feitosa, Maria Fátima da Silva Teixeira, R. R. Pinheiro, Rodrigo Maranguape Silva da Cunha, João Paulo Matos Santos Lima, A. Andrioli, T. V. M. Dantas, Valeska Shelda Pessoa de Melo, Diana Célia Sousa Nunes‐Pinheiro,
Caprine Arthritis Encephalitis virus (CAEV) and Visna/maedi virus (VISNA), are considered to be genetically distinct but antigenically related pathogens of goats and sheep. In this study, one flock of 250 goats was screened using Agar-gel Immunodiffusion (AGID), and the level of seroprevalence observed was 11 animals (4.4%) of positive tested serum. Four goats positive to AGID were analyzed using a Polymerase Chain Reaction (PCR), which amplifies part of the gag gene. All the animals were found to be ...
Tópico(s): Virus-based gene therapy research
2010 - Elsevier BV | Small Ruminant Research
José Arnaldo Shiomi da Cruz, Cesar Thiago, Ugo de Queiros Barros, Ricardo Leo Felts de la Roca, João Paulo Cunha Lima, Ricardo Di Migueli,
... Queiros Barros, Ricardo Leo Felts de la Roca, Joao Paulo Cunha Lima, and Ricardo Di Migueli Jose Arnaldo Shiomi ... de la RocaRicardo Leo Felts de la Roca , Joao Paulo Cunha LimaJoao Paulo Cunha Lima , and Ricardo Di MigueliRicardo ... de la Roca More articles by this author Joao Paulo Cunha Lima More articles by this author Ricardo Di ...
Tópico(s): Kidney Stones and Urolithiasis Treatments
2016 - Lippincott Williams & Wilkins | The Journal of Urology
João G. P. Rodrigues, Mariana Kaiseler, Ana Aguiar, João Paulo Silva Cunha, João Barros,
The experience of daily stress among bus drivers has shown to affect physical and psychological health, and can impact driving behavior and overall road safety. Although previous research consistently supports these findings, little attention has been dedicated to the design of a stress detection method able to synchronize physiological and psychological stress responses of public bus drivers in their day-to-day routine work. To overcome this limitation, we propose a mobile sensing approach to detect ...
Tópico(s): Workplace Health and Well-being
2015 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Intelligent Transportation Systems
Celso Cunha, João Paulo Tavanez, Severin O. Gudima,
Hepatitis delta virus (HDV) is the etiologic agent of the most severe form of virus hepatitis in humans.Sharing some structural and functional properties with plant viroids, the HDV RNA contains a single open reading frame coding for the only virus protein, the Delta antigen.A number of unique features, including ribozyme activity, RNA editing, rolling-circle RNA replication, and redirection for a RNA template of host DNA-dependent RNA polymerase Ⅱ, make this small pathogen an excellent model to ...
Tópico(s): Hepatitis Viruses Studies and Epidemiology
2015 - | World Journal of Virology
Produção Nacional
Revisado por pares
Valdiléa G. Veloso, Carlos Cáceres, Brenda Hoagland, Ronaldo I. Moreira, Hamid Vega-Ramírez, Kelika A. Konda, Iuri Costa Leite, Sergio Bautista‐Arredondo, Marcus Lacerda, José Valdez Madruga, Alessandro Farias, Josué N Lima, Ronaldo Zonta, Lilian M. Lauria, Cesar Vidal Osco Tamayo, Hector Javier Salvatierra Flores, Yovanna Margot Cabrera Santa Cruz, Ricardo Martín Moreno Aguayo, Marcelo Cunha, Júlio Moreira, Alessandra Ramos Makkeda, Steven Díaz, Juan V. Guanira, Heleen Vermandere, Marcos Benedetti, Heather Ingold, Cristina Pimenta, Thiago S. Torres, Beatriz Grinsztejn, J. David Urbaez-Brito, Polyana Monteiro d’Albuquerque, Claudio Palombo, Paulo Ricardo de Alencastro, Raquel Keiko de Luca Ito, João L. Benedetti, Fabio V. Maria, Paula M. Luz, Lucilene Freitas, Kim Mattos Geraldo, Mônica Derrico, Sandro Nazer, Tania Kristic, Renato Girade, Renato Lima, Antônio R. Carvalho, Carla Rocha, Pedro Nuno Leite, Marcio Lessa, Marília Santini-Oliveira, Daniel R. B. Bezerra, Cleo de Oliveira Souza, Jacinto Corrêa, Marcelo Ribeiro‐Alves, Carolina Fischinger Moura de Souza, Camilla Portugal, Mônica dos Santos Valões, Gabriel Lima Mota, Joyce Alves Gomes, C Falcão, Fernanda Falcão Riberson, Luciano Melo, Talita Andrade Oliveira, Agnaldo Moreira Oliveira Júnior, Bruna de Paula Fonseca e Fonseca, Leonor Henriette de Lannoy, Ludymilla Anderson Santiago Carlos, João Paulo Cunha, Sonia Maria de Alencastro Coracini, Thiago Oliveira Rodrigues, Emília Regina Scharf Mettrau, Kelly Vieira Meira, Heder Tavares, Ana Paula Nunes Viveiros Valeiras, Taiane Miyake Alves de Carvalho Rocha, Alex Amorim, Patrícia Sabadini, Luiz Gustavo Córdoba, Caio Gusmão, Erika Faustino, Júlia Hansen, Agatha Mirian Cunha, Neuza Uchiyama Nishimura, Jaime Eduardo Flygare Razo Prereira Santos, Aline Barnabé Cano, W Dias, Magô Tonhon, Tania Regina Rezende, Alex Rodrigues Gomes, Eloá dos Santos Rodrigues, Maria das Dores Aires Carneiro, Alexandre Castilho, Mariana Carvalho, Dulce Díaz-Sosa, Centli Guillén-Díaz-Barriga, Lorena Hernández, Rebeca Robles, María Elena Medina‐Mora, Marcela González, Ivonne Huerta Icelo, Araczy Martinez Davalos, José Gomez Castro, Luis Obed Ocampo Valdez, Fernanda Ramírez Barajas, Verónica Ruiz González, Galileo Vargas Guadarrama, Israel Macías, J. Sánchez, Juan Pablo Osuna Noriega, H. Rodrigo Moheno M, Jorge M. Bernal Ramírez, Víctor Dante Galicia Juarez, Gerardo Iván Martínez Vizcaíno, Francisco Javier Arjona, G Calvo, Silver K. Vargas, Oliver Antonio Elorreaga Reyes, Ximena Gutierrez, Fernando Olivos, Damaris Caviedes, Daniella Adriazola, Eduardo Juárez, Gabriela Mariño, Jazmin Qquellon, Francesca Vasquez, Jean Pierre Jiron, Sonia C. Flores, Karen Campos,
Although gay, bisexual, and other cisgender men who have sex with men (MSM) and transgender women have the highest HIV burden in Latin America, pre-exposure prophylaxis (PrEP) implementation is poor. We aimed to assess the feasibility of same-day oral PrEP delivery in Brazil, Mexico, and Peru.Implementation PrEP (ImPrEP) was a prospective, single-arm, open-label, multicentre PrEP implementation study conducted in Brazil (14 sites), Mexico (four sites), and Peru (ten sites). MSM and transgender women were ...
Tópico(s): LGBTQ Health, Identity, and Policy
2022 - Elsevier BV | The Lancet HIV
Arnaldo Dias‐Santos, Joana Ferreira, Sofia Pinheiro, João Paulo Cunha, Marta Alves, Ana Luísa Papoila, Maria Francisca Moraes‐Fontes, Rui Proença,
To evaluate ocular involvement in a cohort of systemic lupus erythematosus (SLE) patients of a tertiary referral center and to compare the results with the existing literature.Patients underwent a complete ophthalmological evaluation, including visual acuity, slit-lamp examination, fluorescein staining, Schirmer-I test, Goldmann applanation tonometry, fundoscopy, 10-2 automated threshold visual fields, fundus autofluorescence and spectral-domain optical coherence tomography to screen for hydroxychloroquine ( ...
Tópico(s): Ocular Diseases and Behçet’s Syndrome
2020 - SAGE Publishing | Lupus
Nuno Moura‐Coelho, Teresa Valero, Joana Ferreira, Marco Dutra-Medeiros, João Paulo Cunha,
Tópico(s): Cerebral Venous Sinus Thrombosis
2020 - Springer Science+Business Media | Graefe s Archive for Clinical and Experimental Ophthalmology
Maria Elisa Luís, Diogo Hipólito‐Fernandes, Catarina Mota, Diogo Maleita, Catarina Xavier, Tiago Maio, João Paulo Cunha, Joana Ferreira,
Introduction: Human coronavirus (HCoVs) are a group of viruses with recognized neurotropic and neuroinvasive capabilities. The reports on the neurological and ocular findings are increasing day after day and several central and peripheral neurological manifestations are already described. However, none specifically describes the neuro-ophthalmological manifestation of HCoVs. This is the first article specifically reviewing neuro-ophthalmological manifestations of HCoVs infection. Methods: PubMed ...
Tópico(s): Ocular Diseases and Behçet’s Syndrome
2020 - Dove Medical Press | Eye and Brain
Nuno Moura‐Coelho, Joana Ferreira, Carolina Bruxelas, Marco Dutra-Medeiros, João Paulo Cunha, Rita Pinto Proença,
Tópico(s): Protein Kinase Regulation and GTPase Signaling
2019 - Springer Science+Business Media | Graefe s Archive for Clinical and Experimental Ophthalmology
Arnaldo Dias‐Santos, Joana Ferreira, Sofia Pinheiro, João Paulo Cunha, Marta Alves, Ana Luísa Papoila, Maria Francisca Moraes‐Fontes, Rui Proença,
To compare choroidal thickness (CT) between patients with systemic lupus erythematosus (SLE) without ophthalmologic manifestations and a control group. To study the effects in CT of disease duration, activity index, medication and systemic comorbidities.Cross-sectional study where spectral-domain optical coherence tomography with enhanced depth imaging was used to measure CT in 13 locations, subfoveally and at 500-µm intervals along a horizontal and a vertical section from the fovea. Linear regression ...
Tópico(s): Retinal Diseases and Treatments
2019 - Dove Medical Press | Clinical ophthalmology
Joana Cardigos, Quirina Ferreira, Sara Crisóstomo, Nuno Moura‐Coelho, João Paulo Cunha, Luís Abegão Pinto, Joana Ferreira,
Nanotechnology enabled the development of materials and devices with great utility in different fields of medicine. By using engineered-based nano-devices and structures, human biological systems may be controlled and repaired at a molecular scale, ultimately leading to a biological benefit. In particular, in the field of glaucoma treatment, nanotechnology may, for example, enhance drug residence time on the ocular surface and ocular bioavailability, as well as improve surgical success by both optimizing ...
Tópico(s): Ocular Surface and Contact Lens
2018 - Taylor & Francis | Current Eye Research
Arnaldo Dias‐Santos, Rita Pinto Proença, Joana Ferreira, Sofia Pinheiro, João Paulo Cunha, Rui Proença, Maria Francisca Moraes‐Fontes,
Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disorder that can involve any organ system. Central nervous system involvement can be a severe life threatening complication, ultimately resulting in severe neurodegenerative changes. Magnetic resonance imaging suggests that neurodegeneration, which may have deleterious effects on brain function, may occur early in SLE and experimental models suggest that neuroprotection may be feasible and beneficial. The retina is an extension ...
Tópico(s): Protein Tyrosine Phosphatases
2018 - Elsevier BV | Autoimmunity Reviews
João Paulo Cunha, Rita Pinto Proença, Arnaldo Dias‐Santos, Diana Melância, Rita Almeida, Helena Águas, Bruno Oliveira Santos, Marta Alves, Joana Ferreira, Ana Luísa Papoila, Carlota Louro, A. Castanheira–Dinis,
The purpose of this study was to measure and to compare macular choroidal thickness (CT) between patients with mild Alzheimer's disease (AD), patients without AD, and elderly patients.CT was measured manually in 13 locations at 500-μm intervals of a horizontal and a vertical section from the fovea. Linear regression models were used to analyze the data.Fifty patients with a diagnosis of mild AD (73.1 years), 152 patients without AD (71.03 years), and 50 elderly without AD (82.14 years) were included. ...
Tópico(s): Retinal Diseases and Treatments
2017 - Elsevier BV | Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
Joana Ferreira, Rita Pinto Proença, Marta Alves, Arnaldo Dias‐Santos, Bruno Oliveira Santos, João Paulo Cunha, Ana Luísa Papoila, Luís Abegão Pinto,
To identify changes in choroidal thickness (CT) and all retinal layers of diabetic patients without diabetic retinopathy (DR) after 1 year of follow-up.Prospective observational cohort study.Overall, 125 diabetic patients without DR were included. Two visits were scheduled: the first visit (V1) and a second visit after 12 months (V2). At both visits, patients received a complete ophthalmologic evaluation that included OCT. Each retinal layer thickness was calculated for 9 ETDRS sectors, and CT was measured ...
Tópico(s): Glaucoma and retinal disorders
2017 - Elsevier BV | American Journal of Ophthalmology