Produção Nacional
Tópico(s): Psychology and Mental Health
1953 - UNIVERSIDADE DE SÃO PAULO | Revista de Medicina
Produção Nacional
Revisado por pares
Rogério Ferreira Ribas, João Augusto Alves Meira‐Neto, Alexandre Francisco da Silva, Agostinho Lopes de Souza,
O presente estudo foi desenvolvido em dois trechos de floresta semidecídua, com diferentes estádios de sucessão secundária, localizada no município de Viçosa-MG, objetivando verificar variações qualitativas na composição florística. Foram demarcadas, em cada trecho, dez parcelas de 10 x 20 m, nas quais foram inventariados todos os indivíduos lenhosos com circunferência à altura de 130 cm do solo maior ou igual a 5 cm. A similaridade florística entre as parcelas foi avaliada por meio de análise de ...
Tópico(s): Soil Management and Crop Yield
2003 - Sociedade de Investigações Florestais | Revista Árvore
Xavi Ribas, João C. Dias, Jorge Morgado, Klaus Wurst, Isabel C. Santos, Manuel Almeida, J. Vidal-Gancedo, Jaume Veciana, Concepció Rovira,
The deprotonated form of the pyrazine-2,3-diselenol (pds) ligand, pds2-, reacts with NiII inorganic salts to form the nickel compounds [NiII(pds)2](nBu4N)2 (1), [NiII(pds)2]Na2·2H2O (2), and [NiIII(pds)2]2Na2·4H2O (3), depending on the reaction conditions. They are characterized by NMR, EPR, UV−vis, and IR spectroscopies, elemental analysis, cyclic voltammetry, and X-ray crystallography. The crystal structure of compound 3 shows the formation of segregated stacks of Ni(pds)2- units, with a strong dimerization ...
Tópico(s): Metal-Organic Frameworks: Synthesis and Applications
2004 - American Chemical Society | Inorganic Chemistry
Xavi Ribas, João C. Dias, Jorge Morgado, Klaus Wurst, Elı́es Molins, Eliseo Ruíz, Manuel Almeida, Jaume Veciana, Concepció Rovira,
Abstract The deprotonated form of the ligands pyrazine‐2,3‐diselenol (pds) and pyrazine‐2,3‐dithiol (pdt) react with Cu(ClO 4 ) 2 ⋅6 H 2 O to form different Cu III complexes Na[Cu III (pds) 2 ]⋅2 H 2 O ( 1 ), Li[Cu III (pds) 2 ]⋅3 H 2 O ( 2 ), and Na[Cu III (pdt) 2 ]⋅2 H 2 O ( 4 ) depending on the countercation compound used as deprotonating agent (NaOH, LiOH). Two other Cu III complexes were obtained by replacement of the alkali metal cations with tetrabutylammonium (TBA + ), namely, TBA[Cu III (pds) 2 ] ( 3 ), and TBA[Cu III (pdt) 2 ] ( 5 ). All ...
Tópico(s): Polyoxometalates: Synthesis and Applications
2004 - Wiley | Chemistry - A European Journal
Xavi Ribas, João Carlos Teixeira Dias, Jorge Morgado, Klaus Wurst, Manuel Almeida, Teodor Parella, Jaume Veciana, Concepció Rovira,
Surrounded by selenium: Pulse field gradient spin-echo (PGSE) NMR diffusion studies of a mixture of oligomeric 1,2-diselenolene PtIV complexes are performed to characterize the species in solution (see structure: n=0 (1), n=1 (2), n=2 (3); red Pt, green Se, blue N, gray C). The results are in accord with the single-crystal X-ray diffraction structures obtained for the chiral complexes {PtIVSe6} (1) and {PtIV2Se10} (2). Supporting information for this article is available on the WWW under http://www.wiley- ...
Tópico(s): Organometallic Complex Synthesis and Catalysis
2004 - Wiley | Angewandte Chemie International Edition
Produção Nacional
J. C. Franchini, Henrique Debiasi, W. P. Dias, L. N. Ribas, João Flávio Veloso Silva, Alvadi Antônio Balbinot,
Root-lesion nematode (RLN) (Pratylenchus brachyurus) is an important challenge to soybean production in Central Brazil due to its widespread occurrence, along with the absence of resistant cultivars and strategies for its management. The aim of this research was to evaluate the relationship among soil properties, RLN populations, and soybean crop growth using geostatistical analysis. The experiment was conducted in a soybean field located in the northern half of Mato Grosso state, in Brazil, with ...
Tópico(s): Cassava research and cyanide
2015 - UNIVERSIDADE DO ESTADO DE SANTA CATARINA | Revista de Ciências Agroveterinárias
Produção Nacional
Revisado por pares
Lílian Lund Amado, Márcia Longaray Garcia, Patrícia Ramos, Ricardo Franco Freitas, Bruna Zafalon, Josencler L. Ribas Ferreira, João Yúnes, José María Monserrat,
Determination of total antioxidant capacity, instead of the measurements of limited number of antioxidants, is very important for the understanding of how antioxidants interact with reactive oxygen species (ROS). Several techniques already exist with this propose, although some of them are extremely time-consuming. A new methodology is proposed, based on the detection of ROS by fluorometry (ex/em: 485/520 nm) employing 2',7'-dichlorofluorescein diacetate (H(2)DCF-DA) as substrate. Supernatant of homogenized ...
Tópico(s): Marine and coastal ecosystems
2008 - Elsevier BV | The Science of The Total Environment
Nupura S. Bhise, João Ribas, Vijayan Manoharan, Yu Shrike Zhang, Alessandro Polini, Solange Massa, Mehmet R. Dokmeci, Ali Khademhosseini,
Novel microfluidic tools allow new ways to manufacture and test drug delivery systems. Organ-on-a-chip systems — microscale recapitulations of complex organ functions — promise to improve the drug development pipeline. This review highlights the importance of integrating microfluidic networks with 3D tissue engineered models to create organ-on-a-chip platforms, able to meet the demand of creating robust preclinical screening models. Specific examples are cited to demonstrate the use of these systems ...
Tópico(s): Neuroscience and Neural Engineering
2014 - Elsevier BV | Journal of Controlled Release
Nasim Annabi, Šeila Selimović, Juan Pablo Acevedo, João Ribas, Mohsen Afshar Bakooshli, Déborah Heintze, Anthony S. Weiss, Donald M. Cropek, Ali Khademhosseini,
The research areas of tissue engineering and drug development have displayed increased interest in organ-on-a-chip studies, in which physiologically or pathologically relevant tissues can be engineered to test pharmaceutical candidates. Microfluidic technologies enable the control of the cellular microenvironment for these applications through the topography, size, and elastic properties of the microscale cell culture environment, while delivering nutrients and chemical cues to the cells through ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2013 - Royal Society of Chemistry | Lab on a Chip
Produção Nacional
Revisado por pares
Ana Flávia Fernandes Ribas Nardy, João Luiz Silva‐Filho, Ana Rosa Pérez, Juliana de Meis, Désio Aurélio Farias-de-Oliveira, Luciana Penha, Isadora de Araújo Oliveira, Wagner B. Dias, Adriane R. Todeschini, Célio Geraldo Freire-de-Lima, Maria Bellio, Celso Caruso‐Neves, Ana Acácia S. Pinheiro, Christina Maeda Takiya, Óscar Bottasso, Wilson Savino, Alexandre Morrot,
In experimental Trypanosoma cruzi infections, severe thymic atrophy leads to release of activated CD4(+)CD8(+) double-positive (DP) T cells to the periphery. In humans, activated DP T cells are found in the blood in association with severe cardiac forms of human chronic Chagas disease. The mechanisms underlying the premature thymocyte release during the chagasic thymic atrophy remain elusive. We tested whether the migratory properties of intrathymic thymocytes are modulated by the parasite trans- ...
Tópico(s): Research on Leishmaniasis Studies
2013 - Elsevier BV | Microbes and Infection
Produção Nacional
Revisado por pares
Simone Maria Ribas Vendramel, João Paulo Bassin, Márcia Dezotti, Geraldo L. Sant’Anna,
Petroleum refineries produce large amount of wastewaters, which often contain a wide range of different compounds. Some of these constituents may be recalcitrant and therefore difficult to be treated biologically. This study evaluated the capability of an aerobic submerged fixed-bed reactor (ASFBR) containing a corrugated PVC support material for biofilm attachment to treat a complex and high-strength organic wastewater coming from a petroleum refinery. The reactor operation was divided into five ...
Tópico(s): Analytical chemistry methods development
2015 - Taylor & Francis | Environmental Technology
Yu Shrike Zhang, João Ribas, Akhtar Nadhman, Julio Aleman, Šeila Selimović, Sasha Cai Lesher‐Pérez, Ting Wang, Vijayan Manoharan, Su-Ryon Shin, Alessia Damilano, Nasim Annabi, Mehmet R. Dokmeci, Shuichi Takayama, Ali Khademhosseini,
A miniature microscope was designed and fabricated with built-in fluorescence capability for biomedical applications.
Tópico(s): Microfluidic and Bio-sensing Technologies
2015 - Royal Society of Chemistry | Lab on a Chip
Yu Shrike Zhang, Fabio Busignani, João Ribas, Julio Aleman, Talles Nascimento Rodrigues, Seyed Ali Mousavi Shaegh, Solange Massa, Camilla Baj Rossi, Irene Taurino, Su-Ryon Shin, Giovanni Calzone, Givan Mark Amaratunga, Douglas Leon Chambers, Saman Jabari, Yuxi Niu, Vijayan Manoharan, Mehmet R. Dokmeci, Sandro Carrara, Danilo Demarchi, Ali Khademhosseini,
Abstract Google Glass is a recently designed wearable device capable of displaying information in a smartphone-like hands-free format by wireless communication. The Glass also provides convenient control over remote devices, primarily enabled by voice recognition commands. These unique features of the Google Glass make it useful for medical and biomedical applications where hands-free experiences are strongly preferred. Here, we report for the first time, an integral set of hardware, firmware, software, ...
Tópico(s): Microfluidic and Capillary Electrophoresis Applications
2016 - Nature Portfolio | Scientific Reports
Elham A. Masoudi, João Ribas, Gaurav Kaushik, Jeroen Leijten, Ali Khademhosseini,
Platelet rich blood derivatives have been widely used in different fields of medicine and stem cell based tissue engineering. They represent natural cocktails of autologous growth factor, which could provide an alternative for recombinant protein based approaches. Platelet rich blood derivatives, such as platelet rich plasma, have consistently shown to potentiate stem cell proliferation, migration, and differentiation. Here, we review the spectrum of platelet rich blood derivatives, discuss their ...
Tópico(s): Hemostasis and retained surgical items
2016 - Springer Science+Business Media | Current Stem Cell Reports
Peter Newman, Jorge Luis Galenano-Niño, Pamela L. Graney, Joselito M. Razal, Andrew I. Minett, João Ribas, Raquel Ovalle‐Robles, Maté Biro, Hala Zreiqat,
Abstract The topography of a biomaterial regulates cellular interactions and determine stem cell fate. A complete understanding of how topographical properties affect cell behavior will allow the rational design of material surfaces that elicit specified biological functions once placed in the body. To this end, we fabricate substrates with aligned or randomly organized fibrous nanostructured topographies. Culturing adipose-derived stem cells (ASCs), we explore the dynamic relationship between the ...
Tópico(s): Cell Image Analysis Techniques
2016 - Nature Portfolio | Scientific Reports
João Ribas, H. Sadeghi, Amir Manbachi, Jeroen Leijten, Katelyn N. Brinegar, Yu Shrike Zhang, Lino Ferreira, Ali Khademhosseini,
Cardiovascular diseases are prevalent worldwide and are the most frequent causes of death in the United States. Although spending in drug discovery/development has increased, the amount of drug approvals has seen a progressive decline. Particularly, adverse side effects to the heart and general vasculature have become common causes for preclinical project closures, and preclinical models do not fully recapitulate human
Tópico(s): Neuroscience and Neural Engineering
2016 - Mary Ann Liebert, Inc. | Applied In Vitro Toxicology
Neslihan Alemdar, Jeroen Leijten, Gulden Camci‐Unal, Jesper Hjortnaes, João Ribas, Arghya Paul, Pooria Mostafalu, Akhilesh K. Gaharwar, Yiling Qiu, Sameer Sonkusale, Ronglih Liao, Ali Khademhosseini,
Oxygen is essential to cell survival and tissue function. Not surprisingly, ischemia resulting from myocardial infarction induces cell death and tissue necrosis. Attempts to regenerate myocardial tissue with cell based therapies exacerbate the hypoxic stress by further increasing the metabolic burden. In consequence, implanted tissue engineered cardiac tissues suffer from hypoxia-induced cell death. Here, we report on the generation of oxygen-generating hydrogels composed of calcium peroxide (CPO) ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2016 - American Chemical Society | ACS Biomaterials Science & Engineering
Cecília J. Alves, Inês S. Alencastre, Estrela Neto, João Ribas, Sofia Ferreira, Daniel M. Vasconcelos, Daniela M. Sousa, Teresa Summavielle, Meriem Lamghari,
Bone repair is a specialized type of wound repair controlled by complex multi-factorial events. The nervous system is recognized as one of the key regulators of bone mass, thereby suggesting a role for neuronal pathways in bone homeostasis. However, in the context of bone injury and repair, little is known on the interplay between the nervous system and bone. Here, we addressed the neuropeptide Y (NPY) neuronal arm during the initial stages of bone repair encompassing the inflammatory response and ...
Tópico(s): Regulation of Appetite and Obesity
2016 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Sebastião Vieira de Morais, Nicolau Gregori Czeczko, Osvaldo Malafaia, Jurandir Marcondes Ribas-Filho, João Batista Santos Garcia, Marcelo Tizzot Miguel, Cássio ZINI, Angeline Garcez Massignan,
PURPOSE: To evaluate the usefulness of a knee osteoarthritis model through functional, radiological and microscopic changes of the synovial membrane. METHODS: Forty eight rats were divided randomly into two groups. The first received 0.9% saline in the joint and corresponded to the control group. The second was submitted to experimental osteoarthritis of the right knee induced by monosodium iodoacetate and corresponded to the osteoarthritis group. All animals were subjected to comparative tests ...
Tópico(s): Tendon Structure and Treatment
2016 - Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia | Acta Cirúrgica Brasileira
Wei Zhang, Yu Shrike Zhang, Syeda Mahwish Bakht, Julio Aleman, Su Ryon Shin, Kan Yue, Marco Sica, João Ribas, Margaux Duchamp, Jie Ju, Ramin Banan Sadeghian, Duck Jin Kim, Mehmet R. Dokmeci, Anthony Atala, Ali Khademhosseini,
A novel form of a vascular module based on endothelialized PDMS hollow tubes was developed for integrating multiple organs-on-chips.
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2016 - Royal Society of Chemistry | Lab on a Chip
Xu Hou, Yu Shrike Zhang, Grissel Trujillo‐de Santiago, Mario Moisés Álvarez, João Ribas, Steven J. Jonas, Paul S. Weiss, Anne M. Andrews, Joanna Aizenberg, Ali Khademhosseini,
Developments in the field of microfluidics have triggered technological revolutions in many disciplines, including chemical synthesis, electronics, diagnostics, single-cell analysis, micro- and nanofabrication, and pharmaceutics. In many of these areas, rapid growth is driven by the increasing synergy between fundamental materials development and new microfluidic capabilities. In this Review, we critically evaluate both how recent advances in materials fabrication have expanded the frontiers of ...
Tópico(s): Microfluidic and Capillary Electrophoresis Applications
2017 - Nature Portfolio | Nature Reviews Materials
Yu Shrike Zhang, Julio Aleman, Su Ryon Shin, Tuğba Kiliç, Duck Jin Kim, Seyed Ali Mousavi Shaegh, Solange Massa, Reza Riahi, Sukyoung Chae, Ning Hu, Hüseyin Avcı, Wei Zhang, Antonia Silvestri, Amir Sanati‐Nezhad, Ahmad Manbohi, Fabio De Ferrari, Alessandro Polini, Giovanni Calzone, Noor Shaikh, Parissa Alerasool, Erica Budina, Jian Kang, Nupura Bhise, João Ribas, Adel Pourmand, Aleksander Skardal, Thomas Shupe, Colin E. Bishop, Mehmet R. Dokmeci, Anthony Atala, Ali Khademhosseini,
Organ-on-a-chip systems are miniaturized microfluidic 3D human tissue and organ models designed to recapitulate the important biological and physiological parameters of their in vivo counterparts. They have recently emerged as a viable platform for personalized medicine and drug screening. These in vitro models, featuring biomimetic compositions, architectures, and functions, are expected to replace the conventional planar, static cell cultures and bridge the gap between the currently used preclinical ...
Tópico(s): Innovative Microfluidic and Catalytic Techniques Innovation
2017 - National Academy of Sciences | Proceedings of the National Academy of Sciences
João Ribas, Yu Shrike Zhang, Patrícia R. Pitrez, Jeroen Leijten, Mario Miscuglio, Jeroen Rouwkema, Mehmet R. Dokmeci, Xavier Nissan, Lino Ferreira, Ali Khademhosseini,
Organ‐on‐a‐chip platforms seek to recapitulate the complex microenvironment of human organs using miniaturized microfluidic devices. Besides modeling healthy organs, these devices have been used to model diseases, yielding new insights into pathophysiology. Hutchinson‐Gilford progeria syndrome (HGPS) is a premature aging disease showing accelerated vascular aging, leading to the death of patients due to cardiovascular diseases. HGPS targets primarily vascular cells, which reside in mechanically active ...
Tópico(s): RNA Research and Splicing
2017 - Wiley | Small
Tatyana A. Gubin, Hari P. Iyer, Shirlene N. Liew, Aartik Sarma, Alex Revelos, João Ribas, Babak Movassaghi, Zen Chu, Ayesha N. Khalid, Maulik D. Majmudar, Christopher T. Lee,
MIT Hacking Medicine is a student, academic, and community-led organization that uses systems-oriented "healthcare hacking" to address challenges around innovation in healthcare. The group has organized more than 80 events around the world that attract participants with diverse backgrounds. These participants are trained to address clinical needs from the perspective of multiple stakeholders and emphasize utility and implementation viability of proposed solutions. We describe the MIT Hacking Medicine ...
Tópico(s): Scientific Computing and Data Management
2017 - Elsevier BV | Cell Systems
John W. Ramatowski, Christopher Xiang Lee, Aikaterini Mantzavino, João Ribas, Winter Guerra, Nicholas D. Preston, Eva Schernhammer, Lawrence C. Madoff, Britta Lassmann,
A hackathon is best described as an 'innovation marathon'. Derived from the words 'hacking' and 'marathon', it brings together multidisciplinary teams to collaborate intensely over a short period of time to define a problem, devise a solution, and design a working prototype. International scientific meetings are conducive to successful hackathons, providing an audience of expert professionals who describe challenges and ensure the proposed solutions address end-user needs. Collaborations with local ...
Tópico(s): Conferences and Exhibitions Management
2017 - Elsevier BV | International Journal of Infectious Diseases
João Ribas, Joanna Pawlikowska, Jeroen Rouwkema,
Abstract: The field of microphysiological systems (or organs-on-a-chip) experienced, in the past decade, a surge in publications and efforts towards commercialization. Such systems hold the promise to advance drug discovery, diagnostics, and many other areas. In this review we summarize and analyze the current status of the field, describe the commercial advances and discuss standing challenges and the commercial outlook of the field.
Tópico(s): Innovative Microfluidic and Catalytic Techniques Innovation
2018 - AME Publishing Company | Microphysiological Systems
Produção Nacional
Revisado por pares
Shirlene Telmos Silva de Lima, William Marciel de Souza, John Washington Cavalcante, Darlan da Silva Cândido, Marcílio Jorge Fumagalli, Jean‐Paul Carrera, Leda Maria Simões Mello, Fernanda Montenegro de Carvalho Araújo, Izabel Letícia Cavalcante Ramalho, Francisca Kalline de Almeida Barreto, Deborah Nunes de Melo Braga, Adriana Rocha Simião, Mayara Jane Miranda da Silva, Rhaquel de Morais Alves Barbosa Oliveira, Clayton Pereira Silva de Lima, Camila de Sousa Lins, Rafael Ribeiro Barata, Marcelo Nunes Pereira Melo, Michel Platini Caldas de Souza, Luciano Chaves Franco Filho, Fabio Távora, Daniele Rocha Queiróz Lemos, Carlos Henrique Alencar, Ronaldo de Jesus, Vagner Fonseca, Leonardo Hermes Dutra, André Luiz de Abreu, Emerson Luiz Lima Araújo, André Ricardo Ribas Freitas, João Lídio da Silva Gonçalves Vianez Júnior, Oliver G. Pybus, Luiz Tadeu Moraes Figueiredo, Nuno R. Faria, Márcio Roberto Teixeira Nunes, Luciano Pamplona de Góes Cavalcanti, Fábio Miyajima,
Abstract Background Chikungunya virus (CHIKV) emerged in the Americas in 2013 and has caused approximately 2.1 million cases and >600 deaths. A retrospective investigation was undertaken to describe clinical, epidemiological, and viral genomic features associated with deaths caused by CHIKV in Ceará state, northeast Brazil. Methods Sera, cerebrospinal fluid (CSF), and tissue samples from 100 fatal cases with suspected arbovirus infection were tested for CHIKV, dengue virus (DENV), and Zika virus ( ...
Tópico(s): Viral Infections and Outbreaks Research
2020 - Oxford University Press | Clinical Infectious Diseases
Produção Nacional
Revisado por pares
Luciane Ribas Marques, João Eudes Bezerra Filho, Olavo Venturim Caldas,
O objetivo do artigo foi investigar e analisar a percepção de uma amostra de contadores públicos brasileiros sobre a adoção das Normas Brasileiras de Contabilidade Aplicada ao Setor Público no Brasil, atualmente em processo de convergência com as normas da Internacional Federation of Accountants (International Public Sector Accounting Standards). A literatura consultada tem se concentrado em pesquisas quantitativas realizadas a partir das informações contábeis publicadas em prestações de contas junto ...
Tópico(s): Education and Public Policy
2020 - UNIVERSIDADE DE SÃO PAULO | Revista de Contabilidade e Organizações
Produção Nacional
Revisado por pares
Talita Fernanda Augusto Ribas, João Bráullio de Luna Sales, Hugo de Boer, Jarl Andreas Anmarkrud, Renato Oliveira, Marcele Laux, Fabricio dos Anjos Santa Rosa, Guilherme Oliveira, Felippe A. Postuma, Maria A. Gasalla, Jonathan Stuart Ready,
Growing fishing pressure worldwide has led to an increase in the exploitation of cephalopod products in fish markets where these taxa were not traditionally consumed. Squid catches have surged to meet that demand, yet for many species little is known about their role in food webs. Doryteuthis sanpaulensis is an important squid species in southeastern Brazilian fisheries. Despite many previous efforts at morphological analysis of its diet, few demersal and benthic species of fishes, crustaceans and ...
Tópico(s): Identification and Quantification in Food
2021 - Elsevier BV | Fisheries Research
Allan T. Souza, Martina Ilarri, Joana Campos, Felipe O. Ribas, João Carlos Marques, Irene Martins,
Despite the increasing awareness of climate change, few studies have used the Intergovernmental Panel on Climate Change (IPCC) scenarios to simulate the effects of climate change on estuarine populations of crustaceans. The objective of this study was to investigate the effects of temperature and salinity fluctuations on the population dynamics of the shore crab Carcinus maenas at the southern edge of its native range. To this end, a population dynamics model was developed based on experimental and ...
Tópico(s): Marine Biology and Ecology Research
2022 - Elsevier BV | The Science of The Total Environment