Susana Mão de-Ferro, Joana Castela, Daniela Pereira, Paula Chaves, António Dias Pereira,
Endoscopic full-thickness resection (EFTR) is an emerging technique for the treatment of various conditions for which classic endoscopic resection techniques have failed or were considered to be at high risk for perforation. The full-thickness resection device (FTRD) is an over-the-scope system which allows a single-step EFTR. The aim of our study is to describe our experience in EFTR of colorectal lesions using the FTRD.Nine patients (10 colorectal lesions) were proposed for EFTR. Safety, R0 resection ...
Tópico(s): Esophageal Cancer Research and Treatment
2018 - Karger Publishers | GE Portuguese Journal of Gastroenterology
Joana Castela, Susana Mão de Ferro, Isadora Rosa, Pedro Lage, Sara Ferreira, João Pereira da Silva, João Cortez Pinto, Rita Vale Rodrigues, Joana Moleiro, Isabel Claro, Susana Esteves, António Dias Pereira,
Narrow-band imaging (NBI) allows "in vivo" classification of colorectal polyps.We evaluated the optical diagnosis by nonexpert community-based endoscopists in routine clinical practice, the impact of training, and whether the endoscopists could achieve the threshold for the "do not resect" policy.This was an observational study performed in two periods (P1 and P2). Endoscopists had no prior experience in NBI in P1 and applied the technique on a daily basis for 1 year before participation in P2. Lesions ...
Tópico(s): Gastric Cancer Management and Outcomes
2019 - Karger Publishers | GE Portuguese Journal of Gastroenterology
Joana Castela, Miguel Ángel Tapia‐Serrano, Susana Mão de Ferro, Daniela Pereira, Paula Chaves, António Dias Pereira,
Radiofrequency ablation therapy is an effective endoscopic option for the eradication of Barrett's esophagus that appears to reduce the risk of esophageal cancer. A concern associated with this technique is the development of subsquamous/buried intestinal metaplasia, whose clinical relevance and malignant potential have not yet been fully elucidated. Fewer than 20 cases of subsquamous neoplasia after the successful radiofrequency ablation of Barrett's esophagus have been reported to date. Here, ...
Tópico(s): Eosinophilic Esophagitis
2018 - Korean Society of Gastrointestinal Endoscopy | Clinical Endoscopy
(Primeiro Parágrafo do Artigo)Dona Joana, filha de El-Rei D. Duarte, nasceu em 1439, depois da morte de seu pai, e aos dezesseis anos era a mais formosa mulher da Península , e tanto assim que Garibay, no seu Compêndio historial, afirmava: "... la Reyna, que era reputada por la mas hermosa (dama de toda Espana).
Tópico(s): Historical Education and Society
1951 - UNIVERSIDADE DE SÃO PAULO | Revista de História
António Pires, Paula Martins, Ana Margarida Pereira, Patrícia Vaz Silva, Joana Marinho, Margarida Marques, Eduardo Castela, Cristina M. Sena, Raquel Seiça,
Background: Obesity-related comorbidities are present in young obese children, providing a platform for early adult cardiovascular disorders.Objectives: To compare and correlate markers of adiposity to metabolic disturbances, vascular and cardiac morphology in a European pediatric obese cohort.Methods: We carried out an observational and transversal analysis in a cohort consisting of 121 obese children of both sexes, between the ages of 6 and 17 years.The control group consisted of 40 children with ...
Tópico(s): Cardiovascular Function and Risk Factors
2014 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Fernando Magro, Diogo Magalhães, Marta Patita, Bruno Arroja, Paula Lago, Isadora Rosa, Helena Tavares de Sousa, Paula Ministro, Irinia Mocanu, Ana Vieira, Joana Castela, Joana Moleiro, Joana Roseira, Eugénia Cancela, Paula Sousa, Francisco Portela, L Correia, Mafalda Santiago, Sandra Dias, Catarina Alves, Joana Afonso, Silvio Danese, Laurent Peyrin‐Biroulet, Cláudia Camila Dias,
Background and aims Subclinical intestinal inflammation is common in Crohn's disease (CD). We aimed to explore its impact in the disease progression of infliximab-treated patients and the usefulness of fecal calprotectin (FC) and C-reactive protein (CRP) as surrogate minimally invasive biomarkers. Methods The registry-based, prospective, observational, multicenter DIRECT (study to investigate the correlation of fecal calprotectin with serum Drug levels and development of an antI-dRug antibodiEs among adult patients ...
Tópico(s): Autoimmune and Inflammatory Disorders
2021 - Elsevier BV | Clinical Gastroenterology and Hepatology
Fernando Magro, María Manuela Estevinho, Gaia Catalano, Marta Patita, Bruno Arroja, Paula Lago, Isadora Rosa, Helena Tavares de Sousa, Paula Ministro, Irina Mocanu, Ana Vieira, Joana Castela, Joana Moleiro, Joana Roseira, Eugénia Cancela, Paula Sousa, Francisco Portela, L Correia, Paula Moreira, Mafalda Santiago, Sandra Fernandes Dias, Joana Afonso, Silvio Danese, Laurent Peyrin‐Biroulet, Cláudia Camila Dias,
Abstract Background Timely stratification of Crohn's disease (CD) is essential for patients' management. The use of noninvasive accurate biomarkers is key to monitor treatment and to pursue mucosal healing, the ultimate treatment endpoint in CD. Objective We aimed to evaluate the performance of readily available biomarkers and develop risk matrices to predict CD progression. Methods Data from 289 CD patients receiving infliximab (IFX) maintenance therapy for 2 years was collected; those patients were ...
Tópico(s): Eosinophilic Esophagitis
2023 - Wiley | United European Gastroenterology Journal
Joana Castela, Susana Mão de Ferro, Sara Ferreira, Rafael Cabrera, António Dias Pereira,
Tópico(s): Gastrointestinal disorders and treatments
2018 - Springer Science+Business Media | Journal of Gastrointestinal Surgery
Joana Castela, Susana Mão de Ferro, Sara Ferreira, António Dias Pereira,
Tópico(s): Effects of Radiation Exposure
2018 - Karger Publishers | GE Portuguese Journal of Gastroenterology
S. Roth, Émilien Delmont, P. Heudier, R. Kaphan, Éric Cua, Joana Castela, Julien Verdier, R M Chichmanian, J.G. Fuzibet,
Introduction. – Les anticorps monoclonaux anti-TNFα sont un nouveau traitement des polyarthrites rhumatoïdes sévères. Un de leurs effets secondaires potentiels est la survenue d’infections opportunistes graves. Nous rapportons trois cas de tuberculoses disséminées survenant lors du traitement de la polyarthrite rhumatoïde par infliximab. Exégèse. – Une femme âgée de 45 ans, traitée par infliximab, était hospitalisée après la cinquième perfusion pour dyspnée fébrile. Le bilan trouvait une miliaire tuberculeuse ...
Tópico(s): Mycobacterium research and diagnosis
2002 - Elsevier BV | La Revue de Médecine Interne
João Cortez-Pinto, Susana Mão de Ferro, Joana Castela, Isabel Claro, Paula Chaves, António Dias Pereira,
Tópico(s): Pancreatic and Hepatic Oncology Research
2020 - Karger Publishers | GE Portuguese Journal of Gastroenterology
N. Tieulié, P. Heudier, Joana Castela, F. De Salvador, J.G. Fuzibet,
Les atteintes cardiorespiratoires de la maladie de Still de l’adulte (MSA) sont moins connues que les atteintes cutanées et articulaires. L’atteinte pleuropéricardique est la plus fréquente. Les autres manifestations cardiorespiratoires, qui peuvent accompagner ou révéler la maladie, sont de diagnostic plus difficile mais doivent cependant être rapidement reconnues car elles peuvent être vitales. Toutefois, leur pronostic a été transformé par les nouveaux immunosuppresseurs. La pathogénie est incertaine ...
Tópico(s): Hematological disorders and diagnostics
2004 - Elsevier BV | La Revue de Médecine Interne
Pedro Currais, Joana Roseira, Joana Castela, Susana Mão‐de‐Ferro, António Dias Pereira,
Endoscopic full-thickness resection (EFTR) with the full-thickness resection device (Ovesco Endoscopy, Tuebingen, Germany) is used for the resection of subepithelial lesions and adenomas ≤20 mm, nonresectable with the following conventional endoscopic techniques: nonlifting sign or lesions in complex anatomic locations (for example, ileocecal appendix or diverticula). In our center, we performed 16 EFTRs, 10 of them with at least 1 follow-up examination 4 to 6 months after the index procedure.
Tópico(s): Esophageal and GI Pathology
2020 - Elsevier BV | Gastrointestinal Endoscopy
Sophie Roth, J.-P. Campagni, C Perrin, F. Sanderson, Joana Castela, Éric Rosenthal, N. Tieulié, Pierre‐Yves Jeandel, P. Heudier, J.G. Fuzibet,
Tópico(s): Parvovirus B19 Infection Studies
2005 - Elsevier BV | La Revue de Médecine Interne
Produção Nacional
... o Formoso, Arquiduque de Áustria e de dona Joana a Louca, princesa castelhana, neto de D. Fernando II de Aragão e de Dona Isabel I de Castela, pela linha materna, e do Imperador Maximiliano de ...
Tópico(s): Historical Education and Society
1951 - UNIVERSIDADE DE SÃO PAULO | Revista de História
João Pinto, Joana Castela, Susana Mão de Ferro,
Tópico(s): Tumors and Oncological Cases
2018 - Karger Publishers | GE Portuguese Journal of Gastroenterology
João Cortez Pinto, Susana Mão de Ferro, Joana Castela, Inês Claro, Paula Chaves, António Dias Pereira,
Most well-differentiated, non-functional duodenal NETs limited to the mucosa/submucosa can be treated effectively with endoscopic resection.
Tópico(s): Salivary Gland Tumors Diagnosis and Treatment
2019 - Thieme Medical Publishers (Germany) | Endoscopy
Pedro Currais, Susana Mão de Ferro, Joana Castela, António Dias Pereira,
A 57-year-old man who underwent total gastrectomy for gastric adenocarcinoma presented with fever and elevated inflammatory markers on postoperative day 2. Computed tomography (CT) scan and esophagogastroduodenoscopy (EGD) were unremarkable. The patient developed an evisceration and intra-abdominal infected collection, which was managed with a new surgical intervention and antibiotic treatment. He was discharged on postoperative day 33.
Tópico(s): Metastasis and carcinoma case studies
2020 - Thieme Medical Publishers (Germany) | Endoscopy
João Cortez Pinto, Joana Castela, Susana Margarida Mão de Ferro,
Tópico(s): Gastrointestinal Tumor Research and Treatment
2018 - Karger Publishers | GE Portuguese Journal of Gastroenterology
Ana Paula Matos, Joana Castela Lobo,
Revela-se de primordial importância estudar o autoconceito, o coping e a saúde mental de adolescentes com Paralisa Cerebral. Essa população tem sido muito pouco estudada. Além disso, essas variáveis podem contribuir para a adaptação desses jovens que se confrontam com situações mais adversas, podendo ser fatores protetores e de risco da sua saúde psicológica. Estudamos uma amostra de 78 sujeitos com Paralisia Cerebral (idades entre os 12 e os 19 anos). Encontramos os seguintes resultados: a) as moças ...
Tópico(s): Infant Development and Preterm Care
2009 - UNIVERSIDADE DE SÃO PAULO | Psicologia USP
Fernando Magro, Samuel Fernandes, Marta Patita, Bruno Arroja, Paula Lago, Isadora Rosa, Helena Tavares de Sousa, Paula Ministro, Irina Mocanu, Ana Vieira, Joana Castela, Joana Moleiro, Joana Roseira, Eugénia Cancela, Paula Sousa, Francisco Portela, L Correia, Paula Moreira, Sandra Fernandes Dias, Joana Afonso, Silvio Danese, Laurent Peyrin‐Biroulet, Katarina Vučićević, Mafalda Santiago,
Abstract Background and aims Effective management of inflammatory bowel disease (IBD) relies on a comprehensive understanding of infliximab (IFX) pharmacokinetics (PK). This study’s primary goal was to develop a robust PK model, identifying key covariates influencing IFX clearance (CL), while concurrently evaluating the risk of disease progression during the maintenance phase of IBD treatment. Methods The multicenter, prospective, real-world DIRECT study was conducted in several care centers, which ...
Tópico(s): Pregnancy and Medication Impact
2024 - Oxford University Press | Journal of Crohn s and Colitis
Paula Sousa, Marta Patita, Bruno Arroja, Paula Lago, Isadora Rosa, Helena Tavares de Sousa, Paula Ministro, Irina Mocanu, Ana Vieira, Joana Castela, Joana Moleiro, Joana Roseira, Eugénia Cancela, Francisco Portela, L Correia, Mafalda Santiago, Sandra Dias, Catarina Alves, Joana Afonso, Cláudia Camila Dias, Fernando Magro,
BackgroundThe emergence of new treatments the inflammatory bowel diseases (IBD) raised questions regarding the role of older agents, namely thiopurines.AimsTo clarify the benefits of combination treatment with thiopurines on Crohn's disease (CD) patients in the maintenance phase of infliximab.MethodsIn this analysis of the 2-year prospective multicentric DIRECT study, patients were assessed in terms of clinical activity, faecal calprotectin (FC), C-reactive protein (CRP), and infliximab pharmacokinetics. ...
Tópico(s): Acute Lymphoblastic Leukemia research
2023 - Elsevier BV | Digestive and Liver Disease
Joana Castela, Daniela Pereira, Susana Mão‐de‐Ferro,
Tópico(s): Gestational Trophoblastic Disease Studies
2019 - Karger Publishers | GE Portuguese Journal of Gastroenterology
Luís Martins, Rita Oliveira, Patrícia Silva, Joana Marinho, Graça Sousa, Eduardo Castela,
Tópico(s): Congenital Heart Disease Studies
2014 - Elsevier BV | Revista Portuguesa de Cardiologia
Joana Lemos Garcia, Rita Vale Rodrigues, Susana Mão‐de‐Ferro, Sara Ferreira, Miguel Ángel Serrano, Joana Castela, Raquel Sacarrão, Fátima Francisco, Liliana Sousa, António Dias Pereira,
Introduction: Oesophageal cancer causes dysphagia and weight loss. Malnutrition further worsens with multimodal treatment. Aim: The aim of the study was to evaluate the impact of percutaneous endoscopic gastrostomy (PEG) placement in the nutritional status of patients with oesophageal cancer requiring chemoradiotherapy (CRT). Methods: A comparative study with a prospective arm and a historical cohort was conducted. Oesophageal cancer patients undergoing CRT with dysphagia grade >2 and/or weight loss > ...
Tópico(s): Dysphagia Assessment and Management
2022 - Karger Publishers | GE Portuguese Journal of Gastroenterology
D. Magalhães, María José Santiago, Marta Patita, Bruno Arroja, Paula Lago, Isadora Rosa, Helena Tavares de Sousa, P. Ministro, Irina Mocanu, A. Vieira, Joana Castela, Joana Moleiro, Joana Roseira, Conti Eugenia, Paula Sousa, Fernando Victor Monteiro Portela, L. Correia, Sérgio Dias, Joana Afonso, Silvio Danese, Laurent Peyrin‐Biroulet, Catarina Dias, Fernando Magro,
ABSTRACT Background and aims Predicting the treatment outcomes of biological therapies is an unmet need in Crohn's Disease. In this study, we explored the potential of serum neutrophil‐related biomarkers to predict infliximab therapeutic results and disease progression in Crohn's Disease patients, over a 2‐year period, in a real‐world setting. Methods The study included 100 asymptomatic Crohn's Disease patients in the IFX maintenance phase from the prospective, observational, multicenter DIRECT ...
Tópico(s): Autoimmune and Inflammatory Disorders
2024 - Wiley | United European Gastroenterology Journal
Fernando Magro, Samuel Fernandes, Marta Patita, Bruno Arroja, Paula Lago, Isadora Rosa, Helena Tavares de Sousa, Paula Ministro, Irina Mocanu, A. Vieira, Joana Castela, Joana Moleiro, Joana Roseira, Eugénia Cancela, Paula Sousa, Francisco Portela, L Correia, Paula Moreira, Joana Afonso, Sérgio Dias, Silvio Danese, Laurent Peyrin‐Biroulet, Katarina Vučićević, Mafalda Santiago,
Abstract Background Effective management of inflammatory bowel disease (IBD) relies on a comprehensive understanding of infliximab (IFX) pharmacokinetics (PK). This study's primary goal was to develop a robust PK model, identifying key covariates influencing IFX clearance (CL), while concurrently evaluating the risk of disease progression during the maintenance phase of IBD treatment. Methods The multicenter, prospective, real-world DIRECT study was conducted in several care centers, which included ...
Tópico(s): Pregnancy and Medication Impact
2024 - Oxford University Press | Journal of Crohn s and Colitis
Fernando Magro, Samuel Fernandes, Marta Patita, Bruno Arroja, Paula Lago, Isadora Rosa, Helena Tavares de Sousa, Paula Ministro, Irina Mocanu, Ana Vieira, Joana Castela, Joana Moleiro, Joana Roseira, Eugénia Cancela, Paula Sousa, Francisco Portela, L Correia, Paula Moreira, Joana Afonso, Sandra Fernandes Dias, Silvio Danese, Laurent Peyrin‐Biroulet, Katarina Vučićević, Mafalda Santiago,
Tópico(s): Urticaria and Related Conditions
2024 - Elsevier BV | Gastroenterology
Mathilde Versini, P.-Y. Jeandel, Joana Castela, L. Marcq, Éric Rosenthal, J.G. Fuzibet,
The intravesical BCGtherapy is an efficient and recognized treatment for superficial bladder tumors and their repetitions. It is usually well tolerated (in 95% cases) but it can sometimes bring about fearful side effects. We report the case of a 74-year-old man under observation, treated for a superficial bladder tumor by BCG-therapy. Following the fourth course, the patient developped a sepsis and a multiorgan failure witch led to his death on the fifth day of his hospitalization in spite of the ...
Tópico(s): Infectious Disease Case Reports and Treatments
2010 - Elsevier BV | La Revue de Médecine Interne
J Lemos Garcia, Rébecca Rodrigues, Susana Mão‐de‐Ferro, Sara Ferreira, M. García-Oria, Sandra Faias, Joana Castela, R Sacarrão, Fátima Francisco, Juliana Mól Trindade, Liliana B. Sousa, Araída Dias Pereira,
Aims Oesophageal cancer in advanced stages causes dysphagia and weight loss. Malnutrition further worsens with multimodal treatment. Our aim was to evaluate the impact of percutaneous endoscopic gastrostomy (PEG) placement in the nutritional status of patients with oesophageal cancer requiring chemoradiotherapy (CRT).
Tópico(s): Clinical Nutrition and Gastroenterology
2021 - Thieme Medical Publishers (Germany) | Endoscopy