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Artigo Acesso aberto Revisado por pares

Toby Gardner, Joice Ferreira, Jos Barlow, Alexander Charles Lees, Luke Parry, Ima Célia Guimarães Vieira, Érika Berenguer, Ricardo Abramovay, Alexandre Luis Padovan Aleixo, Christian Borges Andretti, Luiz E. O. C. Aragão, Ivanei S. Araujo, Williams Souza de Ávila, Richard D. Bardgett, Mateus Batistella, Rodrigo Anzolin Begotti, Troy Patrick Beldini, Driss Ezzine de Blas, Rodrigo Fagundes Braga, Danielle de Lima Braga, Janaína Gomes de Brito, Plínio Barbosa de Camargo, Fabiane Campos dos Santos, Vívian Campos de Oliveira, Amanda Cardoso Nunes Cordeiro, Thiago Moreira Cardoso, Débora Reis de Carvalho, Sergio André Castelani, Júlio Cézar Mário Chaul, Carlos Eduardo Pellegrino Cerri, Francisco de Assis Costa, Carla Daniele Furtado da Costa, Émilie Coudel, A. C. Coutinho, Dênis Antônio da Cunha, Álvaro de Oliveira D’Antona, Joelma Dezincourt, Karina Dias‐Silva, Mariana Durigan, Júlio César, José Gustavo Feres, Sílvio Frosini de Barros Ferraz, Amanda Estefânia de Melo Ferreira, Ana Carolina Oliveira Fiorini, Lenise Vargas Flôres da Silva, Fábio Frazão, Rachael Garrett, Alessandra dos Santos Gomes, Karoline da Silva Gonçalves, José Benito Guerrero, Neusa Hamada, Robert M. Hughes, Danilo Carmago Igliori, Ederson da Conceição Jesus, Leandro Juen, Miércio Júnior, José Max Barbosa de Oliveira, Raimundo Cosme de Oliveira, Carlos Souza, P.R. Kaufmann, Vanesca Korasaki, Cecília Gontijo Leal, Rafael P. Leitão, Natália Lima, Maria de Fátima Lopes Almeida, Reinaldo Lourival, Júlio Louzada, Ralph Mac Nally, Sébastien Marchand, M. M. Maués, Fátima Maria de Souza Moreira, Carla Morsello, Nárgila Moura, Jorge Luiz Nessimian, Sâmia Nunes, Victor Hugo Fonseca Oliveira, Renata Pardini, Heloisa Correia Pereira, Paulo dos Santos Pompeu, Carla R. Ribas, Felipe Rossetti, Fernando Augusto Schmidt, Rodrigo da Silva, Regina Célia Viana Martins da Silva, Thiago Fonseca Morello Ramalho da Silva, Juliana M. Silveira, João Victor Siqueira, Teotônio Soares de Carvalho, Ricardo Solar, Nicola Savério Holanda Tancredi, James R. Thomson, Patrícia Carignano Torres, Fernando Zagury Vaz‐de‐Mello, Ruan Carlo Stülpen Veiga, Adriano Venturieri, Cecília Viana, Diana Weinhold, Ronald Zanetti, Jansen Zuanon,

... Alexandre Camargo, Cunha Dênis, D'Antona Álvaro, Dezincourt Joelma, Dias-Silva Karina, Durigan Mariana, Esquerdo Júlio César ... PubMed Search for more papers by this author , Joelma Dezincourt Joelma Dezincourt Google Scholar Find this author on PubMed ... Antona Google Scholar Find this author on PubMed , Joelma Dezincourt Joelma Dezincourt Google Scholar Find this author on PubMed , ... Alexandre Camargo Coutinho, Dênis Cunha, Álvaro D'Antona, Joelma Dezincourt, Karina Dias-Silva, Mariana Durigan, Júlio César ...

Tópico(s): Land Use and Ecosystem Services

2013 - Royal Society | Philosophical Transactions of the Royal Society B Biological Sciences

Artigo Revisado por pares

Lauro T. Kubota, Yoshitaka Gushikem, Joelma Perez, Auro Atsushi Tanaka,

... on Silica Gel SurfaceLauro T. Kubota, Yoshitaka Gushikem, Joelma Perez, and Auro A. TanakaCite this: Langmuir 1995, ...

Tópico(s): Porphyrin and Phthalocyanine Chemistry

1995 - American Chemical Society | Langmuir

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Rayssa Gabriella Moi de Souza, Joelma Nascimento de Souza, Joelma Figueiredo Menezes, Leda Maria Alcântara, Neci Matos Soares, Márcia Cristina Aquino Teixeira,

Introduction: Nematodes of Trichostrongylus genus are mainly parasites of herbivores, although sporadic human infections have been reported in many countries.Objective: To describe the frequency and seasonality of Trichostrongylus spp. infection in individuals attended at a public clinical laboratory.Materials and methods: Fecal samples of 9,283 individuals were evaluated by spontaneous sedimentation (Lutz) in the Parasitology Laboratory of the Pharmacy College, Federal University of Bahia, Brazil, ...

Tópico(s): Parasites and Host Interactions

2013 - National Institute of Health | Biomédica

Artigo Brasil Produção Nacional Revisado por pares

Seiti Inoue Venturini, Denis R. M. Godoi, Joelma Perez,

A deep understanding of the ammonia oxidation reaction (AOR) over platinum surfaces may facilitate the use of ammonia as a carbon-free source for energy storage and conversion. Herein, using an unprecedented experimental approach of combining online electrochemical mass spectrometry (OLEMS) and ion chromatography (IC) with high-area Pt/C surfaces, many AOR products were simultaneously detected and the variation in AOR selectivity depending on the surface conditions was demonstrated. In the low-potential ...

Tópico(s): Caching and Content Delivery

2023 - American Chemical Society | ACS Catalysis

Artigo Brasil Produção Nacional Revisado por pares

Kaline do Nascimento Ferreira, Raonil R Oliveira, Lúcio Roberto Cançado Castellano, Paulo Rogério Ferreti Bonan, Otávio Valério de Carvalho, Lindomar Pena, Joelma Rodrigues de Souza, Juliano Elvis de Oliveira, Eliton S. Medeiros,

Herpetic dermatitis and oral recurrent herpes (ORH) are among the most common human infections. Antiviral drugs such as acyclovir (ACV) are used in the standard treatment for ORH. Despite its therapeutic efficacy, ACV is continuously and repetitively administered in high doses. In this sense, the development of controlled release drug delivery systems such as core-shell fibers have a great potential in the treatment of ORH. In this work, poly(lactic acid)/poly(ethylene glycol) (PLA/PEG) fibers were ...

Tópico(s): Electrospun Nanofibers in Biomedical Applications

2022 - Elsevier BV | Biomaterials Advances

Artigo Revisado por pares

Joelma Choma, Eduardo Guerra, Alexandre Álvaro, Roberto Pereira, Luciana Zaina,

Software startups work under uncertain market conditions, constant time pressures, and extremely limited resources. Startup practitioners commonly adopt agile practices and lean development to build and release software quickly. Within this context, User eXperience (UX) work is critical for generating user value and creating a competitive advantage. However, integrating agile and UX remains an open question and little explored in software startups. In this study, we investigate how startup practitioners ...

Tópico(s): Software Engineering Techniques and Practices

2022 - Elsevier BV | Information and Software Technology

Artigo Brasil Produção Nacional Revisado por pares

Daniela Carla de Souza, Joelma Gonçalves Martin, Vanessa Soares Lanziotti, Cláudio Flauzino de Oliveira, Cristian Tedesco Tonial, Werther Brunow de Carvalho, José Roberto Fioretto, Jefferson Pedro Piva, Eduardo Juan Troster, Aline Siqueira Bossa, F. Gregorini, Josiane F. Ferreira, J Lubarino, Alexandre Biasi Cavalcanti, Flávia Ribeiro Machado, SC Silva, Juliana Giacomazzi, Domingos A. Boldrini, FH Gilli, LC de Castro, ML de Albuquerque, VCTG Osorio, MLC Elias, AA da Câmara, Marcelo de Oliveira Maia, PB de Carvalho, FM Augusto, RCCM de Figueiredo, EL Ikino, FAS Nogueres, RJ de Almeida, Lara de Araújo Torreão, Joana Ramalho, MMS Camões, CS de Oliveira, VIIS Serafim, José Colleti, CG de Almeida, MHM da Costa, JF Valerio, ME Navajas, PM Riveiro, AZ Lubiana, A Cristián Brito, V Moretto, LMMD Rachid, Maria Carolina Vieira Valle, PP de Souza, RPL Victor, NR Castro, T Sakomura, Marizete Elisa Molon, A. E. Ferreira, JG da Fonseca, VCA Cunali, VCA Chagas, G Belek, T. d. Rocha, LCFF de Mello, L.Z. Machado, NV Moliterno, C Castillo Duran, CLEB Sanos, G.P.A.R. Ribeiro, PSL da Silva, Ruth Lipinski, Ana Lucia Rodrigues Soledade, KC Branco, ACO Teles, GF da Cruz, MR de Mendonça, Éder Felipe Rosado Malheiros, Joseph J. Vicari, PNT Izidro, NMP Campos, TC Pontes, CRF Carneiro, AH Imamura, FM Yoshioka, MCMB Duarte, Thiago S. Menezes, Claudia Falconiere, Francisco Frederico Dos Santos Matos, RS Zeitel, CC Nogueras, ML da Silva, M Aprille, TYM Pires, AF Portella, PM Riveiro, PVG Flores, PP Alfradique, RC Nascimento, MO Saldanha, A. S Alves, WJ de Almeida, Maiara Bortoli Rodrigues, E Lopes Júnior, MRP Komka, M.A. De Luca Nascimento, CRC Lopes, TMC Bernardi, RV Falcão, AR Fraga, Machado Aa, J.C. Godoy, José Fernando Marques Barcellos, RLS Queiroz, VVS de Almeida, J A Lira, Miriam Alvo, TCP Peçanha, AM de Sousa, CS Sanches, AR Wendhausen, SR Pinheiro, MA Orione, AM Minossi, NL Bresolin, C. Tzanno Branco Martins, VF Cury, RPB Quinet, A. P. C. Netto, R Limonge, SST Tamari, SER de Souza, Rafael Veiga, NGCB Couto, M.H. Ribeiro, AK de Aguiar, Maurizio Evangelista, JR Krauzer, Herbert Müller, DHS Genu, P Alvares, K. Lamenza Maciel, FT Valente, Maraísa Centeville, GJ Espinheira, A. Da Silva, PL Vasconcelos, AZ Hädrich, ALDGC Sousa, GA Gandra, PB de Carvalho, ACA Souto, Linda M. Sabatini, PRD João, A.C.H.R. Machado, F.A. Fonseca, APA Resende, RV da Silva, TP da Silva, LLT Barros, CSV de Souza, Ko Harada, D Calçado, LSB Pinheiro, MCM Frota, LB Pulcheri, LM e Silva, KJ dos Santos, FH de Nuncio, IO Gomes Júnior, ACC Gomes, MA Klitzke, FR de Souza, FSC Carvalho, FP de Lima, LR Braun Filho, MAG de Oliveira, Thuanny Castilho, IP Pistelli, JD Paccez, Clara García Cendón, R Sapolnick, Dilson Fronza, Cara E. Toscan, RM Pinelli, JV Alencar, HL di Pace, AD Ramos, AC Molinari, JF Assis, APCR Chavarri, RC Pereira, CL Freitas, ICDM Salmen, RCM Guerini, Junko Asakura, ACR Pires, G. Benvenuti, L. Castelo Branco Camurça Fernandes, NF Oliveira, HJB Barros, LCE Nascimento, MB Machado, AOR dos Santos, AC da Silva, JV Alencar, ACE de Oliveira, SKY Reinheimer, PCS Mello, I.M.G Araújo, KLC Rodrigues, MN Amari, Maria Andersson, LMCM Petrini, AKSF Luz, ESS Serafim, RF Barbosa, Daniela Carla de Souza, AF Delgado, ALP Guerra, JY Afiune, John Huber, Sílvia Casonato, DCB da Silva, OR de Araujo, FMD Fialho, LFR Soares, AA de Queiroz Júnior, A Sartorelli, ACP Zuccoli, M Castelani, LAA da Silva, SRA Lima, MJSL de Araújo, ACS da Cruz, PM Sillero, G Sgorlon, T.S. Alves, MMB Muniz, RHP Pereira, NR Gonçalves, RPV Teixeira, I. d. A. Barros Vasconcelos, CT Rossetti, RG Cesar, M. C. C. ALVES, MK Martins, J.V. Sarmento Rocha, Luciano Rodrigo Peres Arruda, ALY Grillo, Guilherme Barros,

Tópico(s): Nosocomial Infections in ICU

2021 - Elsevier BV | The Lancet Child & Adolescent Health

Artigo Brasil Produção Nacional Revisado por pares

Joelma Leão-Buchir, Nilce Mary Turcatti Folle, Tugstênio Lima de Souza, Patrícia Manuitt Brito, Elton Celton de Oliveira, Aliciane de Almeida Roque, Wanessa Algarte Ramsdorf, Luís Fernando Fávaro, Juan Ramón Esquivel Garcia, Luíse Esquivel, Francisco Filipak Neto, Ciro Alberto de Oliveira Ribeiro, Maritana Mela Prodócimo,

Polybrominated diphenyl esters are emerging environmental contaminants with few toxicological data, being a concern for the scientific community. This study evaluated the effects of BDE-47 on the health of Oreochromis niloticus fish. The animals were exposed to three doses of BDE-47 (0, 0.253, 2.53, 25.3 ng g−1) every 10 days, for 80 days. The BDE-47 affected the hepatosomatic and gonadosomatic index in female and the condition factor by intermediate dose in both sexes. The levels of estradiol decreased ...

Tópico(s): Effects and risks of endocrine disrupting chemicals

2021 - Elsevier BV | Environmental Toxicology and Pharmacology

Artigo Brasil Produção Nacional Revisado por pares

Katyanne Viana da Conceição, Michel Eustáquio Dantas Chaves, Michelle Cristina Araújo Picoli, Alber Sánchez, Anderson R. Soares, Guilherme Mataveli, Daniel E. Silva, Joelma S. Costa, Gilberto Câmara,

The Brazilian Amazon rainforest deforestation rate increased by 34.1% between 2018 and 2019, reaching even protected areas, such as Indigenous Lands (ILs). In particular, Ituna/Itatá IL, in the state of Pará, restricted to the study of Igarapé Ipiaçava isolated indigenous people, has experienced a 654% deforestation rate increase during the same period. The mainstream deforestation analysis explains it as a struggle between conservation and development, which is commonly typified by large-scale producers ...

Tópico(s): Amazonian Archaeology and Ethnohistory

2021 - Elsevier BV | Land Use Policy

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gabriel Rodrigues Coutinho Pereira, Bárbara Abrahim-Vieira, Joelma Freire De Mesquita,

Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disorder, with a significant social and economic burden. ALS remains incurable, and the only drugs approved for its treatments confers a survival benefit of a few months for the patients. Missense mutations in superoxide dismutase 1 (SOD1), a major cytoplasmic antioxidant enzyme, has been associated with ALS development, accounting for 23% of its familial cases and 7% of all sporadic cases. This work aims to characterize in silico ...

Tópico(s): Neurogenetic and Muscular Disorders Research

2021 - Public Library of Science | PLoS ONE

Artigo Brasil Produção Nacional Revisado por pares

Joelma Silva de Almeida, Regina Fátima Fernandes, Áurea Castelo Branco Andrade, Bruna da Costa Almeida, Anderson Nixon da Silva Amorim, Jorge Henrique da Cunha Mascarenhas Lustosa, Regina Ferraz Mendes, Raimundo Rosendo Prado Júnior,

Abstract Aim To evaluate the impact of dental treatment on the oral health‐related quality of life (OHRQoL) of children and adolescents with Autism Spectrum Disorder (ASD), through the perception of caregivers. Methods and results A prospective longitudinal study was conducted on 115 individuals with ASD, 6‐14 years of age, recruited from the referral centers for special needs individuals at Teresina, Brazil. A clinical examination was carried out and the OHRQoL was measured using the Brazilian version ...

Tópico(s): HIV/AIDS oral health manifestations

2021 - Wiley | Special Care in Dentistry

Artigo Acesso aberto Brasil Produção Nacional

Joelma Correia Beraldo Braga, Luan Ramos da Silva,

As plantas medicinais são utilizadas para o tratamento, cura e prevenção de doenças. Podem ser utilizadas de forma isolada ou ainda como matéria prima para síntese de fármacos ou fitoterápicos. A pandemia causada pelos vírus SARS-COV 2 que leva a doença COVID-19, ameaça a população atualmente, e a preocupação com a imunidade tem sido constante para evitar os danos causados pela doença e sua letalidade. Diante disto, o objetivo deste trabalho foi determinar o perfil de consumidores de plantas medicinais ...

Tópico(s): Agricultural and Food Sciences

2021 - Brazilian Journal of Development | Brazilian Journal of Health Review

Capítulo de livro Acesso aberto Brasil Produção Nacional

Sofia A. M. Silveira, Joelma Choma, Roberto Pereira, Eduardo Guerra, Luciana Zaina,

Abstract Software start-ups develop innovative software products working with disruptive technologies in time pressure and market-driven environment. Recently, User eXperience (UX) has become a hot topic that interests software teams of start-ups. However, software and UX professionals have struggled to match UX practices into the development activities, partially because of the lack of resources in the start-ups. This paper investigates how software start-ups handle UX activities during software ...

Tópico(s): Service and Product Innovation

2021 - Springer Science+Business Media | Lecture notes in business information processing

Artigo Acesso aberto Brasil Produção Nacional

Vívian Martins, Joelma Almeida,

Refletimos a respeito do andamento dos processos educativos no Brasil em meio ao distanciamento social forçado por uma pandemia em escala mundial. Apresentamos o parecer do Conselho Nacional de Educação que sugere a contabilização das atividades pedagógicas não presenciais para o cumprimento da carga horária mínima estabelecida pela LDB. Consideramos tal proposição problemática por desconsiderar as diferentes realidades e desigualdades sociais do país, já que nem todos os estudantes possuem condições ...

Tópico(s): Education and Digital Technologies

2020 - UNIVERSIDADE DO ESTADO DO RIO DE JANEIRO | Revista Docência e Cibercultura

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Joelma Kyone Silva de Oliveira, Darlena Caroline da Cruz Corrêa, Antônio Marcos Quadros Cunha, Aníbal Coutinho do Rêgo, Cristian Faturi, Wilton Ladeira da Silva, Felipe Nogueira Domingues,

The use of nitrogen fertilization in tropical grasslands is a strategy that may reduce the pressure of livestock production on biome areas with humid forests. The objective of this study was to assess the use of different doses of nitrogen in Guinea grass (Megathyrsus maximus (Jacq.) con. Mombasa) cultivated in the humid tropics. Doses of 0, 10, 20, 30, 40, and 50 kg of N ha−1 application−1 were applied during two consecutive years in experimental plots. The experimental area is located in the northeast ...

Tópico(s): Ruminant Nutrition and Digestive Physiology

2020 - Multidisciplinary Digital Publishing Institute | Agronomy

Artigo Brasil Produção Nacional Revisado por pares

Luan Alberto Andrade, Daniele Aparecida de Oliveira Silva, Cleiton Antônio Nunes, Joelma Pereira,

The objective of this study was to analyze existing taro mucilage extraction techniques for extraction of a pure product with high emulsifying action to chemically characterize the mucilage. Five taro mucilage extraction techniques were analyzed which used room temperature, 4 °C, or 80 °C, with or without ethanol precipitation. Protein was detected in the mucilage extracted by each method and is ideal for the emulsifying action. Only mucilage extracted at low temperature and precipitated with ethanol ...

Tópico(s): Food composition and properties

2020 - Elsevier BV | Food Chemistry

Artigo Brasil Produção Nacional Revisado por pares

Luana Lopes Padilha, Élcio Oliveira Vianna, Andressa Talícia Machado Vale, Joelma Ximenes Prado Teixeira Nascimento, Antônio Augusto Moura da Silva, Cecília Cláudia Costa Ribeiro,

Abstract Studies on the exposure of children to sugar‐sweetened beverages (SSBs) at an early age may contribute to better understand the common causes and the temporal order of the relationships between obesity and asthma in early childhood. The objective of this study was to estimate the association between SSB and child asthma traits in the 2nd year of life, modeling direct and indirect pathways mediated by the highest BMI‐z of the child and allergic inflammation. Data from the BRISA cohort, São ...

Tópico(s): Obesity, Physical Activity, Diet

2020 - Wiley | Pediatric Allergy and Immunology

Artigo Brasil Produção Nacional Revisado por pares

Joelma Villafanha Gandolfi, Ana Paula Altimari Di Bernardo, Débora Augusto Valverde Chanes, Danilo Fernando Martin, Vanessa Bonafim Joles, Cristina Prata Amêndola, Luciana Coelho Sanches, Gustavo Larsen Ciorlia, Suzana Margareth Lobo,

Objectives: To evaluate whether the use of exogenous melatonin affects sleep, reduces the prevalence of delirium, and decreases the need for analgosedation and to assess whether serum melatonin indices correlate with exogenous administration in critically ill patients. Design: Double-blind, randomized, placebo-controlled study. Setting: Multicenter ICUs of two tertiary hospitals. Patients: A total of 203 adult patients who were admitted to the ICU and administered with analgesics and/or sedatives. ...

Tópico(s): Respiratory Support and Mechanisms

2020 - Lippincott Williams & Wilkins | Critical Care Medicine

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ana Carolina Oliveira Siqueira, Gabriel Moura Mascarin, Cassiara R. N. C. B. Gonçalves, Joelma Marcon, Maria Carolina Quecine, Antônio Figueira, Ítalo Delalibera,

The interaction between Metarhizium spp., a genus of entomopathogenic fungi, and plant roots may provide a resourceful association to induce host plant growth and to control below- and above-ground pests and diseases. We conducted in vivo and in vitro bioassays using native Brazilian isolates of Metarhizium robertsii (ESALQ 1635), M. humberi (ESALQ 1638), and M. anisopliae (ESALQ 1669) to better understand the possible mechanisms related to plant growth promotion traits and colonization of the root ...

Tópico(s): Entomopathogenic Microorganisms in Pest Control

2020 - Frontiers Media | Frontiers in Sustainable Food Systems

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Fred Bernardes Filho, Jaci Maria Santana, Regina Coeli Palma de Almeida, Glauber Voltan, Natália Aparecida de Paula, Marcel Nani Leite, Cláudia Maria Lincoln Silva, Camila Cristina Tormena, Lean Basoli, Joelma Figueiredo Menezes, Moisés Batista da Silva, John S. Spencer, Wilson Marques, Norma Tiraboschi Foss, Marco Andrey Cipriani Frade,

Background This study evaluates an active search strategy for leprosy diagnosis based on responses to a Leprosy Suspicion Questionnaire (LSQ), and analyzing the clinical, immunoepidemiological and follow-up aspects for individuals living in a prison population. Methods A cross-sectional study based on a questionnaire posing 14 questions about leprosy symptoms and signs that was distributed to 1,400 prisoners. This was followed by dermatoneurological examination, anti-PGL-I serology and RLEP-PCR. ...

Tópico(s): Ocular Diseases and Behçet’s Syndrome

2020 - Public Library of Science | PLoS neglected tropical diseases

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Marfran C. D. Santos, Joelma D. Monteiro, Josélio Maria Galvão de Araújo, Kássio M. G. Lima,

Abstract Significant attempts are being made worldwide in an attempt to develop a tool that, with a simple analysis, is capable of distinguishing between different arboviruses. Herein, we employ molecular fluorescence spectroscopy as a sensitive and specific rapid tool, with simple methodology response, capable of identifying spectral variations between serum samples with or without the dengue or chikungunya viruses. Towards this, excitation emission matrices (EEM) of clinical samples from patients ...

Tópico(s): Metabolomics and Mass Spectrometry Studies

2020 - Nature Portfolio | Scientific Reports

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Myller de Sousa Tonhá, Daniel F. Araújo, Rafael Pereira de Araújo, Bruno Cunha, Wilson Machado, Joelma Ferreira Portela, João PR Souza, Hikari Kobayashi de Carvalho, Elton Luiz Dantas, Henrique Llacer Roig, Patrick Seyler, Jérémie Garnier,

The Paraiba do Sul (PSR) and Guandu Rivers (GR) water diversion system (120 km long) is located in the main industrial pole of Brazil and supplies drinking water for 9.4 million people in the metropolitan region of Rio de Janeiro. This study aims to discern the trace metals dynamics in this complex aquatic system. We used a combined approach of geochemical tools such as geochemical partitioning, Zn isotopes signatures, and multivariate statistics. Zinc and Pb concentrations in Suspended Particulate ...

Tópico(s): Mercury impact and mitigation studies

2020 - Elsevier BV | Journal of Environmental Sciences

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Caroline Conceição da Guarda, Sètondji Cocou Modeste Alexandre Yahouédéhou, Rayra Pereira Santiago, Joelma Santana dos Santos Neres, Camila Felix de Lima Fernandes, Milena Magalhães Aleluia, Camylla Vilas Boas Figueiredo, Luciana Magalhães Fiuza, Suéllen Pinheiro Carvalho, Rodrigo Mota de Oliveira, Cleverson Alves Fonseca, Uche Samuel Ndidi, Valma Maria Lopes Nascimento, Larissa Carneiro Rocha, Marilda de Souza Gonçalves,

Sickle cell disease (SCD) consists of a group of hemoglobinopathies in which individuals present highly variable clinical manifestations. Sickle cell anemia (SCA) is the most severe form, while SC hemoglobinopathy (HbSC) is thought to be milder. Thus, we investigated the clinical manifestations and laboratory parameters by comparing each SCD genotype. We designed a cross-sectional study including 126 SCA individuals and 55 HbSC individuals in steady-state. Hematological, biochemical and inflammatory ...

Tópico(s): Blood groups and transfusion

2020 - Public Library of Science | PLoS ONE

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gabriel Rodrigues Coutinho Pereira, Gustavo Duarte Bocayuva Tavares, Marta Costa de Freitas, Joelma Freire De Mesquita,

The tryptophan hydroxylase 2 (TPH2) enzyme catalyzes the first step of serotonin biosynthesis. Serotonin is known for its role in several homeostatic systems related to sleep, mood, and food intake. As the reaction catalyzed by TPH2 is the rate-limiting step of serotonin biosynthesis, mutations in TPH2 have been associated with several psychiatric disorders (PD). This work undertakes an in silico analysis of the effects of genetic mutations in the human TPH2 protein. Ten algorithms were used to predict ...

Tópico(s): Bioinformatics and Genomic Networks

2020 - Public Library of Science | PLoS ONE

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Rajaiah Alexpandi, Joelma Freire De Mesquita, Shunmugiah Karutha Pandian, Arumugam Veera Ravi,

The novel coronavirus SARS-CoV-2 disease "COVID-19" emerged in China and rapidly spread to other countries; due to its rapid worldwide spread, the WHO has declared this as a global emergency. As there is no specific treatment prescribed to treat COVID-19, the seeking of suitable therapeutics among existing drugs seems valuable. The structure availability of coronavirus macromolecules has encouraged the finding of conceivable anti-SARS-CoV-2 therapeutics through in silico analysis. The results reveal ...

Tópico(s): Synthesis and biological activity

2020 - Frontiers Media | Frontiers in Microbiology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Daniel Melo de Oliveira Campos, Cláudio Bruno Silva de Oliveira, Joelma Maria de Araújo Andrade, Jonas Ivan Nobre Oliveira,

The current COVID-19 pandemic caused by the novel coronavirus (SARS-CoV2) poses a threat to global health owing to its high rate of spread and severe forms of respiratory infection. The lack of vaccines and antivirals prevents clinical strategies against the disease, creating an emerging need for the development of safe and effective treatments. Strategies for vaccine development include complete vaccines against viruses, subunits, and nucleic acids, but are still in their early stages. Studies carried ...

Tópico(s): SARS-CoV-2 detection and testing

2020 - Instituto Internacional de Ecologia (Brazil) | Brazilian Journal of Biology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Joelma da Silva Souza, Gelson do Santos Difante, João Virgínio Emerenciano Neto, Ângela Maria Quintão Lana, Francisca Fernanda da Silva Roberto, Pedro Henrique Cavalcante Ribeiro,

This study was undertaken to examine biometric measurements during the growth phase of male and female Santa Inês sheep reared in Brachiaria brizantha pastures in northeastern Brazil. The experiment involved 24 castrated males and 24 females at an initial age of 90 days, with an average body weight of 19.04 ± 0.96 kg. Treatments consisted of the effect of four cultivars (Marandu, Xaraés, Piatã and Paiaguás) and two sexes. Six animals were used per treatment, in a randomized-block experimental design. ...

Tópico(s): Livestock Management and Performance Improvement

2019 - Public Library of Science | PLoS ONE

Artigo Brasil Produção Nacional Revisado por pares

Aloma Nogueira Rebello Da Silva, Gabriel Rodrigues Coutinho Pereira, Lorena Giannini Alves Moreira, Catielly Ferreira Rocha, Joelma Freire De Mesquita,

Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is characterized by the selective loss of motor neurons. Approximately 5% to 10% of patients with ALS have a family history of the disease, and approximately 20% of familial amyotrophic lateral sclerosis (fALS) cases are associated with mutations in Cu/Zn superoxide dismutase (SOD1). In this study, we evaluated the structural and functional effects of human A4F and A4V SOD1 protein mutations. We performed an in silico ...

Tópico(s): Parkinson's Disease Mechanisms and Treatments

2019 - Wiley | Journal of Cellular Biochemistry