Giles Smith, Gráinne Gilmore, Andrew Robson, Andrew Norfolk and Ben Hoyle, Colin Bell, Janice Turner, Christina Hardyment, William Shatner, Jeremy Skidmore, Robert Cole, Andrew Pierce, Neelam Verjee, Frank Stark, George Maddocks, Greg Hurst Political Correspondent, Gary Duncan, Simon Barnes, John Lambert, Victoria Solt Dennis, Peter Lansley, Paul Hoggart, Mark Souster, Mark Frary, David Rose, Edward Owen and Daniel McGrory, Clare Lazaro, Emma Cook, Philip Howard, Jack Swabb in 1946, David Chater, Kate Wighton, James Bone, James Ducker, Stephen Woolley, Joel Rickett, Clive Davis, Alexandra Frean Social Affairs Correspondent, Kate Reardon, Elizabeth Judge, Graham Stewart, Kevin toolis, Nicola Christie, Bess Twiston-Davies, R. C. Atkins, Giles Coren, Caroline Hendrie, Antonia Senior, Dr Copperfield, Nancy Durrant, Valerie Elliott Countryside Editor, Jane MacArtney, Thom Burnett, Hilary Rose, Stewart Tendler Crime Correspondent, Anthony Browne, Tom Bawden, Ruth Gledhill, Matt Robert, Debra Craine, Gary Jacob, Dominic Monaghan, Allan Simmons, Joe Morgan, Dr Jane Collins, Tim Reid, Jeanette Winterson, Toby Moore, Dan Sabbagh, Dalya Alberge Arts Correspondent, Ainsley Newson, Jane Clarke, Owen M. Jubb, Candida Crewe, Helen Monks, Alan Hamilton, Stephen Farrell, Nicholas Roe, Rhys Blakely, Richard Lloyd Parry, David Hands, Jonathan Richards, Michael Glover, Heather McGregor, Matt Dickinson Chief Football Correspondent, Liz Chong, David Charter, Tim Teeman, Derwent May, Graham Wood, Dr George Lewith, Richard owen, Ed Potton, Gary Duncan Economics Editor, Oliver Kay, Amber Cowan, Stephen Anderton, Mark Atherton, Lisa Armstrong, Joan Warner, Ed Smith, Rick Broadbent, John Westerby, Tim Cooper, John Hopkins, Pete Paphides, Neel Mukherjee, Ann Treneman, Simon de Bruxelles, Rob Wright, Geoffrey Dean, Christina Koning, Magnus Grimond, Neil Harman Tennis Correspondent, Martin Samuel, Raymond Keene, Kate Saunders, Matthew Pryor, John Russell Taylor, Richard Brass, Matt Hughes, Rebecca O'Connor, Alison Sinclair, Rosemary Bennett Deputy Political Editor, Mike Hildesley, Nigel Hawkes, Tim Worstall, Rick Jones, Zoë Strimpel, Matthew Green, Chris Campling, Patrick Hosking, Richard Owen, Andrew Collins, Christopher Martin-Jenkins Chief Cricket Correspondent, Rebecca O'connor, Sudi Pigott, Mick Hume, Erica Wagner, Roger Boyes, Marcel Berlins, Ross Leckie, David Mattin, Mark Irving, Nick Hasell, Richard Mills, Robin Maynard, Margaret Reynolds, David Hands Rugby Correspondent, Tony Cascarino, Kevin Maher, Julian Muscat, Paul Simons, Nicholas Clee, Steve Jelbert, P.f. Marlow, Nigel Kendall, Nick Szczepanik, John Goodbody, Anne Ashworth, Amrit Dhillon, Joanna Pitman, James Doran, Tom Cox, Tiger Lil, Keith Hopcroft, Jane Shilling, Julie Burchill, Mel Webb, Dominic Maxwell, Sarah Shannon, Roderick Strange, Matthew Parris, Virginia Blackburn, Amanda Craig, George Caulkin, Mike Low, Gordon Lishman, Keith Blackmore, John Angerson, Neil Fisher, Iain Finlayson, Walter Gammie, Anthony Loyd, Ben MacIntyre, Elizabeth Burgess, Shirley Henderson, Richard Beeston Diplomatic Editor, Elizabeth Noyes, Peter Jenson, Graham Searjeant, John Naish, Jacqueline Bealing, Jeremy Page and Luba Vinogradova, Catherine Philp, Chris Ayres, Martin Waller, Carl Mortished International Business Editor, Nigel Hawkes Health Editor, Eric Sykes, Anna Shepard, Darian Leader, Lenny Henry, Roger Dobson, Dr Thomas Stuttaford, Marianne Curphey, Peter Lamont, Stephen Dalton, Nicola Woolcock, Ian G. Townsend Director-General, Alyson Rudd, Richard Morrison, Tom Chesshyre, James Christopher, Alice Miles, Valerie Grove, Justin Francis, Michael Evans, Alan Jackson, Alexandra Blair Education Correspondent, Rick Stein, Owen Slot, Olav Bjortomt, Cath Urquhart Travel Editor, Harry Hill, Will Hide, Pete Paphided, Jenny Davey, Peter Klinger, Bat Ye'or, Patience Wheatcroft, Joe Bolger, Christopher Irvine, Raekha Prasad, Irma Kurtz, Brian McBride,
... Will Make your mind up time Can Benjamin Kunkel's debut novel, Indecision, live up to its ... Morocco Back to the Land Until recently traditional, small-scale farming seemed to be dying out in ...
2005 - Gale Group | TDA
... in the Leguminosae. Bibliografia Genetica 12: 175– 336. Small, John Kunkel 1933 Manual of the southeastern Flora. New York. ...
Tópico(s): Ecology and Vegetation Dynamics Studies
1956 - Wiley | American Anthropologist
1938 - American Association for the Advancement of Science | Science
Previous articleNext article FreeCurrent LiteratureNorth American Flora. John Kunkel Small , George Valentine Nash , Nathaniel Lord Britton , Joseph Nelson Rose , Per Axel Rydberg J. M. C.J. M. C. Search for more articles by ...
Tópico(s): Plant and animal studies
1905 - University of Chicago Press | Botanical Gazette
... 1933. Manual of the southeastern flora. New York: John Kunkel Small. 1,554pp.
Tópico(s): Ecology and Vegetation Dynamics Studies
1959 - Wiley | Journal of Wildlife Management
... 100 years after they were first surveyed by John Kunkel Small found that the liverwort flora is mostly intact. ...
Tópico(s): Peatlands and Wetlands Ecology
2015 - American Bryological and Lichenological Society | Evansia
Tópico(s): Plant Taxonomy and Phylogenetics
1895 - American Association for the Advancement of Science | Science
... Hayes, Thomas Hirschhorn, Andreas Huyssen, Silvia Kolbowski, Benjamin Kunkel, Hari Kunzru, Rachel Kushner, James Benning, John Lansdowne, Thomas J. Lax, An-My Lê, Sarah Lewis, Alex Lichtenstein, Andrew Lichtenstein, Greil Marcus, Achille Mbembe, Sarah Nuttall, Naeem Mohaiemen, Maya Nadkarni, Steven Nelson, Tavia Nyong'o, Ruth B. Phillips, Chris Reitz, Cameron Rowland, Kirk Savage, Gregory Sholette, Robert Slifkin, Irene V. Small, Jason E. Smith, Martino Stierli, Dell Upton, Mabel ...
Tópico(s): Visual Culture and Art Theory
1997 - University of Chicago Press | Speculum
Robert Noble, A. John Bailer, Suzanne Kunkel, Jane Straker,
Tópico(s): Economic and Environmental Valuation
2006 - Springer Science+Business Media | Health Services and Outcomes Research Methodology
Eric C. Polley, Mark W. Kunkel, David M. Evans, Thomas Silvers, René Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Michael Selby, John Connelly, Erik Harris, Nicole Fer, Dmitriy Sonkin, Gurmeet Kaur, Anne Monks, Shakun Malik, Joel Morris, Beverly A. Teicher,
Background: Small cell lung carcinoma (SCLC) is an aggressive, recalcitrant cancer, often metastatic at diagnosis and unresponsive to chemotherapy upon recurrence, thus it is challenging to treat. Methods: Sixty-three human SCLC lines and three NSCLC lines were screened for response to 103 US Food and Drug Administration–approved oncology agents and 423 investigational agents. The investigational agents library was a diverse set of small molecules that included multiple compounds targeting the same ...
Tópico(s): Peptidase Inhibition and Analysis
2016 - Oxford University Press | JNCI Journal of the National Cancer Institute
Nabendu Pore, Song Wu, Nathan Standifer, Maria Jure‐Kunkel, Melissa de los Reyes, Yashaswi Shrestha, Rebecca Halpin, Raymond Rothstein, Kathy Mulgrew, Stephen Blackmore, Philip Martin, John Meekin, Matthew E. Griffin, Ina Bisha, Theresa A. Proia, Ricardo J. Miragaia, Ronald Herbst, Ashok Gupta, Shaad E. Abdullah, Rajiv Raja, Melanie M. Frigault, J. Carl Barrett, Phillip A. Dennis, Maria Libera Ascierto, Michael D. Oberst,
Mutations in the STK11 (LKB1) gene regulate resistance to PD-1/PD-L1 blockade. This study evaluated this association in patients with nonsquamous non-small cell lung cancer (NSCLC) enrolled in three phase I/II trials. STK11 mutations were associated with resistance to the anti-PD-L1 antibody durvalumab (alone/with the anti-CTLA4 antibody tremelimumab) independently of KRAS mutational status, highlighting STK11 as a potential driver of resistance to checkpoint blockade. Retrospective assessments of ...
Tópico(s): Tuberculosis Research and Epidemiology
2021 - American Association for Cancer Research | Cancer Discovery
Julia Krushkal, Thomas Silvers, William C. Reinhold, Dmitriy Sonkin, Suleyman Vural, John Connelly, Sudhir Varma, Paul S. Meltzer, Mark W. Kunkel, Annamaria Rapisarda, David M. Evans, Yves Pommier, Beverly A. Teicher,
Abstract Background Small cell lung cancer (SCLC) is an aggressive neuroendocrine lung cancer. SCLC progression and treatment resistance involve epigenetic processes. However, links between SCLC DNA methylation and drug response remain unclear. We performed an epigenome-wide study of 66 human SCLC cell lines using the Illumina Infinium MethylationEPIC BeadChip array. Correlations of SCLC DNA methylation and gene expression with in vitro response to 526 antitumor agents were examined. Results We found ...
Tópico(s): Chromatin Remodeling and Cancer
2020 - BioMed Central | Clinical Epigenetics
John C. Byrd, Timothy J. Murphy, Robin Howard, Margaret S. Lucas, Amy Goodrich, Kathy Park, Michael Pearson, Jamie K. Waselenko, Geoffrey Ling, Michael R. Grever, Antonio J Grillo-López, J. Rosenberg, Lori Kunkel, Ian W. Flinn,
PURPOSE: Rituximab has been reported to have little activity in small lymphocytic lymphoma (SLL)/chronic lymphocytic leukemia (CLL) and to be associated with significant infusion-related toxicity. This study sought to decrease the initial toxicity and optimize the pharmacokinetics with an alternative treatment schedule. PATIENTS AND METHODS: Thirty three patients with SLL/CLL received dose 1 of rituximab (100 mg) over 4 hours. In cohort I (n = 3; 250 mg/m 2 ) and cohort II (n = 7; 375 mg/m 2 ) rituximab was ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
2001 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
John F. Galliher, Karl R. Kunkel, Daryl J. Hobbs,
Tópico(s): Crime, Deviance, and Social Control
1986 - Springer Science+Business Media | Contemporary Crises
Albert M. Ding, John Temple, David C. Kunkel,
concentration at the end of treatment was 123.5, 123.3 and 112.06 mg/g of stool in patients receiving Remicade, Inflectra and Humira respectively.Relapse was claimed in 6 (8,7%), 3 (13,04%), and 5 (14,29%) patients respectively, during follow up (p-value 0,684), and was comparable in 3 observed groups.Allergic reactions that were reported during treatment with both infliximabs (Remicade and Inflectra) were also comparable.Conclusion: We have shown for the first time efficacy and safety of biosimilar ...
Tópico(s): Colorectal Cancer Screening and Detection
2016 - Elsevier BV | Gastroenterology
Nathalie Kunkel, John G. Bartholomew, Laurent Binet, Akio Ikesue, Philippe Goldner,
We present a case study on Eu3+-doped Y2O3 transparent ceramics in which high-resolution laser spectroscopy is used as a material characterization tool. By comparing the results from coherent and incoherent optical spectroscopy with other characterization methods, we show that optical techniques can deliver supplementary information about the local environment of the activator ions in materials. Thus, high-resolution spectroscopy may be of interest for the investigation of a wider range of rare ...
Tópico(s): Atomic and Subatomic Physics Research
2016 - American Chemical Society | The Journal of Physical Chemistry C
Michal H. Kolář, Gábor Nagy, John Kunkel, Sara M. Vaiana, Lars V. Bock, Helmut Grubmüller,
The ribosome is a fundamental biomolecular complex that synthesizes proteins in cells. Nascent proteins emerge from the ribosome through a tunnel, where they may interact with the tunnel walls or small molecules such as antibiotics. These interactions can cause translational arrest with notable physiological consequences. Here, we studied the arrest caused by the regulatory peptide VemP, which is known to form α-helices inside the ribosome tunnel near the peptidyl transferase center under specific ...
Tópico(s): Protein Structure and Dynamics
2022 - Oxford University Press | Nucleic Acids Research
Ricardo M. Attar, Joan M. Carboni, Janet Dell-John, Ann Greer, Donald Hawken, Warren Hurlburt, Maria Jure‐Kunkel, Frank Lee, Liang Schweizer, Marco M. Gottardis, Becky Penhallow, Cheryl A. Rizzo, Thomas E. Spires, Mark D. Wittman,
4471 Prostate cancer is the second leading cause of cancer related death in men in the United States. The androgen receptor (AR) is a transcription factor whose activity is essential for the development and maintenance of the prostate gland. Upon the binding of testosterone or dihydrotestosterone (DHT), the AR regulates the expression of genes involved in proliferation, survival, and differentiation. Based on this, the most common treatment for tumors that recur to the first line treatment, that is, ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2007 - American Association for Cancer Research | Cancer Research
John H. Marks, Emily Kunkel, Jean F. Salem, Charles T. Martin, Brigitte Anderson, Samir Agarwal,
BACKGROUND: Many transanal platforms have been developed to address the challenge of reach and vision when operating transanally. The single-port robot was specifically designed for narrow-aperture surgery and is a promising platform for minimally invasive transanal surgery. OBJECTIVE: The purpose of this phase II trial is to evaluate the safety and feasibility of the initial clinical experience with single-port robot transanal minimally invasive surgery. DESIGN: In a prospective phase II trial, ...
Tópico(s): Colorectal Cancer Screening and Detection
2021 - Lippincott Williams & Wilkins | Diseases of the Colon & Rectum
Konrad Aden, Kareen Bartsch, Joseph M. Dahl, Martin A.M. Reijns, Daniela Esser, Raheleh Sheibani‐Tezerji, Anupam Sinha, Felix Wottawa, Go Ito, Neha Mishra, Katharina Knittler, Adam Burkholder, Lina Welz, Johan H. van Es, Florian Tran, Simone Lipinski, Nassim Kakavand, Christine Boeger, Ralph Lucius, Witigo von Schoenfels, Clemens Schafmayer, Lennart Lenk, Athena Chalaris, Hans Clevers, Christoph Röcken, Christoph Kaleta, Stefan Rose‐John, Stefan Schreiber, Thomas A. Kunkel, Björn Rabe, Philip Rosenstiel,
Background & AimsRNase H2 is a holoenzyme, composed of 3 subunits (ribonuclease H2 subunits A, B, and C), that cleaves RNA:DNA hybrids and removes mis-incorporated ribonucleotides from genomic DNA through ribonucleotide excision repair. Ribonucleotide incorporation by eukaryotic DNA polymerases occurs during every round of genome duplication and produces the most frequent type of naturally occurring DNA lesion. We investigated whether intestinal epithelial proliferation requires RNase H2 function and ...
Tópico(s): DNA Repair Mechanisms
2018 - Elsevier BV | Gastroenterology
Jonathan M. Elkins, Vita Fedele, M. Szklarz, K.R. Abdul Azeez, E. Salah, Jowita Mikolajczyk, Sergei Romanov, Nikolai F. Sepetov, Xi‐Ping Huang, Bryan L. Roth, Ayman Al Haj Zen, Denis Fourches, Eugene Muratov, Alex Tropsha, Joel Morris, Beverly A. Teicher, Mark W. Kunkel, Eric C. Polley, Karen Lackey, Francis Atkinson, John P. Overington, Paul Bamborough, Susanne Müller, Daniel J. Price, Timothy M. Willson, David H. Drewry, Stefan Knapp, William J. Zuercher,
A well-characterized library of experimental kinase inhibitors provides leads for targeting the untargeted kinome. Despite the success of protein kinase inhibitors as approved therapeutics, drug discovery has focused on a small subset of kinase targets. Here we provide a thorough characterization of the Published Kinase Inhibitor Set (PKIS), a set of 367 small-molecule ATP-competitive kinase inhibitors that was recently made freely available with the aim of expanding research in this field and as ...
Tópico(s): Histone Deacetylase Inhibitors Research
2015 - Nature Portfolio | Nature Biotechnology
Andrea M. Kaminski, John M. Pryor, Dale A. Ramsden, Thomas A. Kunkel, Lars C. Pedersen, Katarzyna Bębenek,
Genomic integrity is threatened by cytotoxic DNA double-strand breaks (DSBs), which must be resolved efficiently to prevent sequence loss, chromosomal rearrangements/translocations, or cell death. Polymerase μ (Polμ) participates in DSB repair via the nonhomologous end-joining (NHEJ) pathway, by filling small sequence gaps in broken ends to create substrates ultimately ligatable by DNA Ligase IV. Here we present structures of human Polμ engaging a DSB substrate. Synapsis is mediated solely by Polμ, ...
Tópico(s): Cancer therapeutics and mechanisms
2020 - Nature Portfolio | Nature Communications
Lucía Allais, Noel W. Anderson, Andrew Weiner, Tania Bruguera, Tom Burr, Mary Carroll, Cassils, Paul Chan, Andrew Cole, Michael Diers, Sam Durant, Joanna Fiduccia, Noah Fischer, Finbarr Barry Flood, Eric Foner, Coco Fusco, Renée Green, Rachel Harrison, Sharon Hayes, Thomas Hirschhorn, Andreas Huyssen, Silvia Kolbowski, Benjamin Kunkel, Hari Kunzru, Rachel Kushner, James Benning, John Lansdowne, Thomas J. Lax, An-My Lê, Sarah Lewis, Alex Lichtenstein, Andrew Lichtenstein, Greil Marcus, Achille Mbembé, Sarah Nuttall, Naeem Mohaiemen, Maya Nadkarni, Steven Nelson, Tavia Nyong’o, Ruth B. Phillips, Chris Reitz, Cameron Rowland, Kirk Savage, Gregory Sholette, Robert Slifkin, Irene V. Small, Jason Smith, Martino Stierli, Dell Upton, Mabel O. Wilson, Jessica Winegar,
“A Questionnaire on Monuments” features 49 responses to questions formulated by Leah Dickerman, Hal Foster, David Joselit, and Carrie Lambert-Beatty: “From Charlottesville to Cape Town, there have been struggles over monuments and other markers involving histories of racial conflict. How do these charged situations shed light on the ethics of images in civil society today? Speaking generally or with specific examples in mind, please consider any of the following questions: What histories do these ...
Tópico(s): Law in Society and Culture
2018 - The MIT Press | October
Andreas Lundqvist, Vincent van Hoef, Xiaonan Zhang, Erik Wennerberg, Julie Lorent, Kristina Witt, Laia Masvidal Sanz, Shuo Liang, Shannon Murray, Ola Larsson, Rolf Kiessling, Yumeng Mao, John-William Sidhom, Catherine Bessell, Jonathan J. Havel, Jonathan P. Schneck, Timothy A. Chan, Eliot Sachsenmeier, David M. Woods, Anders Berglund, Rupal Ramakrishnan, Andressa L. Sodré, Jeffrey S. Weber, Roberta Zappasodi, Yanyun Li, Jingjing Qi, Phillip Wong, Cynthia A. Sirard, Michael A. Postow, Walter Newman, Henry Koon, Vamsidhar Velcheti, Margaret K. Callahan, Jedd D. Wolchok, Taha Merghoub, Lawrence G. Lum, Minsig Choi, Archana Thakur, Abhinav Deol, Gregory Dyson, Anthony F. Shields, Cara Haymaker, Marc Uemura, Ravi Murthy, Marihella James, Daqing Wang, Julie Brevard, Catherine Monaghan, S. Swann, James Geib, Mark Cornfeld, Srinivas K. Chunduru, Sudhir Agrawal, Cassian Yee, Jennifer A. Wargo, Sapna P. Patel, Rodabe N. Amaria, Hussein A. Tawbi, Isabella C. Glitza, Scott E. Woodman, Wen‐Jen Hwu, Michael A. Davies, Patrick Hwu, Willem W. Overwijk, Chantale Bernatchez, Adi Diab, Erminia Massarelli, Neil H. Segal, Vincent Ribrag, Ignacio Melero, Tara C. Gangadhar, Walter J. Urba, Dirk Schadendorf, Robert L. Ferris, Roch Houot, Franck Morschhauser, Theodore F. Logan, Jason J. Luke, William Sharfman, Fabrice Barlési, Patrick A. Ott, Laura Mansi, Shivaani Kummar, Gilles Salles, Cecilia Carpio, Roland Meier, Suba Krishnan, Dan McDonald, Matthew Maurer, Xuemin Gu, Jaclyn Neely, Satyendra Suryawanshi, Ronald Levy, Nikhil I. Khushalani, Jennifer Wu, Jinyu Zhang, Fahmin Basher, Mark P. Rubinstein, Mark J. Bucsek, Guanxi Qiao, Cameron R. MacDonald, Bonnie H. Hylander, Elizabeth Repasky, Shilpak Chatterjee, Anusara Daenthanasanmak, Paramita Chakraborty, Kyle Toth, Megan Meek, Elizabeth Garrett‐Mayer, Michael I. Nishimura, Chrystal M. Paulos, Craig Beeson, Xuezhong Yu, Shikhar Mehrotra, Fei Zhao, Kathy S. Evans, Christine Xiao, Alisha Holtzhausen, Brent A. Hanks, Nicole E. Scharping, Ashley V. Menk, Rebecca Moreci, Ryan D. Whetstone, Rebekah Dadey, Simon P. Watkins, Robert L. Ferris, Greg M. Delgoffe, Jonathan U. Peled, Sean M. Devlin, Anna Staffas, Melissa Lumish, Kori Porosnicu Rodriguez, Katya Ahr, Miguel‐Angel Perales, Sergio Giralt, Ying Taur, Eric G. Pamer, Marcel R.M. van den Brink, Robert R. Jenq, Nicola Annels, Hardev Pandha, Guy R. Simpson, Hugh Mostafid, Kevin J. Harrington, Alan Melcher, Mark Grose, Bronwyn Davies, Gough G. Au, Roberta Karpathy, Darren R. Shafren, Jacob Ricca, Taha Merghoub, Jedd D. Wolchok, Dmitriy Zamarin, Luciana Batista, Florence Marliot, Angela Vasaturo, Sabrina Carpentier, Cécile Poggionovo, Véronique Frayssinet, Jacques Fieschi, Marc Van den Eynde, Franck Pagès, Jérôme Galon, Fabienne Hermitte, Sean G. Smith, Khue Thy Nguyen, Sruthi Ravindranathan, Bhanu Koppolu, David A. Zaharoff, Gustavo Schvartsman, Roland Bassett, Jennifer L. McQuade, Lauren E. Haydu, Michael A. Davies, Hussein A. Tawbi, Isabella C. Glitza, Douglas E. Kline, Xiufen Chen, Dominick Fosco, Justin Kline, Abigail E Overacre-Delgoffe, Maria Chikina, Erin A. Brunazzi, Gulidanna Shayan, William A. Horne, Jay K. Kolls, Robert L. Ferris, Greg M. Delgoffe, Tullia C. Bruno, Creg J. Workman, Dario A.A. Vignali, Prasad S. Adusumilli, Ephraim Ansa-Addo, Zihai Li, Andrew B. Gerry, Joseph P. Sanderson, Karen Howe, Roslin Y. Docta, Qian Gao, Eleanor A. L. Bagg, Nicholas D. Tribble, Miguel Maroto, Gareth J. Betts, Natalie Bath, Luca Melchiori, Daniel E. Lowther, Indu Ramachandran, Gabor Kari, Samik Basu, Gwendolyn Binder-Scholl, Karen Chagin, Lini Pandite, Tom Holdich, Rafael G. Amado, Hua Zhang, John Glod, Donna Bernstein, Bent K. Jakobsen, Crystal L. Mackall, Ryan Wong, Jonathan D. Silk, Katherine Adams, Garth Hamilton, Alan Bennett, Sara Brett, Junping Jing, Adriano Quattrini, Manoj Saini, Guy E. Wiedermann, Andrew B. Gerry, Bent K. Jakobsen, Gwendolyn Binder-Scholl, Joanna Brewer, MyLinh Duong, Lu An, Peter Chang, Aruna Mahendravada, Nicholas Shinners, Kevin M. Slawin, David M. Spencer, Aaron E. Foster, J. Henri Bayle, Cristina Bergamaschi, Sinnie Sin Man Ng, Bethany A. Nagy, Shawn M. Jensen, Xintao Hu, Candido Alicea, B. Fox, Barbara K. Felber, George Pavlakis, Jessica Chacon, Tori N. Yamamoto, Thomas Garrabrant, Luis Martínez Cortina, Daniel J. Powell, Marco Donia, Julie Westerlin Kjeldsen, Rikke Fredslund Andersen, Marie Christine Wulff Westergaard, Valentina Bianchi, Mateusz Legut, Meriem Attaf, Garry Dolton, Barbara Szomolay, Sascha Ott, Rikke Lyngaa, Sine Reker Hadrup, Andrew K. Sewell, Inge Marie Svane, Aaron E. Fan, Takumi Kumai, Esteban Celis, Ian S. Frank, Amanda Stramer, Michelle A. Blaskovich, Seth Wardell, Maria Fardis, James Bender, Michael T. Lotze, Stephanie L. Goff, Nikolaos Zacharakis, Yasmine Assadipour, Todd D. Prickett, Jared J. Gartner, Robert Somerville, Mary Helen Black, Hui Xu, Harshini Chinnasamy, Isaac Kriley, Lily Lu, John R. Wunderlich, Paul F. Robbins, Steven Rosenberg, Steven A. Feldman,
### O1 IL-15 primes an mTOR-regulated gene-expression program to prolong anti-tumor capacity of human natural killer cells #### Andreas Lundqvist1, Vincent van Hoef1, Xiaonan Zhang1, Erik Wennerberg2, Julie Lorent1, Kristina Witt1, Laia Masvidal Sanz1, Shuo Liang1, Shannon Murray3, Ola Larsson1,
BMJ
John Kunkel, Gerdenis Kodis, Gábor Nagy, Christophe Bignon, Lillian Otteson, Sonia Longhi, Andrea C. Vaiana, Helmut Grubmüller, Wenwei Zheng, Sara M. Vaiana,
NTAIL is the intrinsically disordered C-terminal domain of the measles virus nucleoprotein N. NTAIL protrudes from the nucleocapsid where the viral RNA is packaged. It recruits the polymerase and enables viral replication upon binding to a folded domain of protein P (PXD). The binding occurs via a coupled folding and binding mechanism, in which a small NTAIL region acts as binding recognition motive and folds into an κ-helix (κ-MoRE). The remaining portion of NTAIL remains disordered upon binding.
Tópico(s): Viral Infections and Immunology Research
2022 - Elsevier BV | Biophysical Journal
Nathan P. Coussens, Thomas S. Dexheimer, Eric M. Jones, Thomas Silvers, John R. Britt, Ronald C. Taylor, Mark W. Kunkel, James H. Doroshow, Beverly A. Teicher,
... Thomas S. Dexheimer, Eric M. Jones, Thomas Silvers, John R. Britt, Ronald C. Taylor, Mark W. Kunkel, James H. Doroshow, Beverly A. Teicher. Development and ...
Tópico(s): Science, Research, and Medicine
2024 - American Association for Cancer Research | Cancer Research
Michael C. Haffner, Güneş Güner, Diana Taheri, George J. Netto, Doreen N. Palsgrove, Qizhi Zheng, Liana B. Guedes, Kunhwa Kim, Harrison Tsai, David Esopi, Tamara L. Lotan, Rajni Sharma, Alan K. Meeker, Arul M. Chinnaiyan, William G. Nelson, Srinivasan Yegnasubramanian, Jun Luo, Rohit Mehra, Emmanuel S. Antonarakis, Charles G. Drake, Angelo M. De Marzo,
... T.L. Xu H. Korman A.J. Jure-Kunkel M. Agrawal S. McDonald D. Kollia G.D. ... T.L. Xu H. Korman A.J. Jure-Kunkel M. Agrawal S. McDonald D. Kollia G.D. ... T.L. Xu H. Korman A.J. Jure-Kunkel M. Agrawal S. McDonald D. Kollia G.D. ... a collection of primary prostatic tumors from the Johns Hopkins Hospital (n = 539) represented on 14 tissue ... resection specimens from men with mCRPC from the Johns Hopkins Hospital (n = 28); and the third was ... 1199-1208Crossref PubMed Scopus (30) Google Scholar The Johns Hopkins Hospital mCRPC cohort (n = 28) comprised two ...
Tópico(s): Immunotherapy and Immune Responses
2018 - Elsevier BV | American Journal Of Pathology
Helga Weber, José R. Valbuena, Mustafa A. Barbhuiya, Stefan Stein, Hana Kunkel, Patricia García, Carolina Bizama, Ismael Riquelme, Jaime A. Espinoza, Stephen E. Kurtz, Jeffrey W. Tyner, Juan F. Calderón, Alejandro H. Corvalán, Manuel Grez, Akhilesh Pandey, Pamela Leal, Juan Carlos Roa,
... Mustafa A. Barbhuiya 4 , Stefan Stein 5 , Hana Kunkel 5 , Patricia García 3, 6 , Carolina Bizama 3, ... 4 McKusick-Nathans Institute of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA ... Chemistry, Department of Oncology, Department of Pathology, The Johns Hopkins University School of Medicine Baltimore, MD, USA * ...
Tópico(s): Toxin Mechanisms and Immunotoxins
2017 - Impact Journals LLC | Oncotarget
Olivia J Kirtley, Julie Janssens, Aleksandra Kaurin,
... in articleCrossref, Google ScholarKirtley, O. J., Hiekkaranta, A., Kunkels, Y. K., Eisele, G., Verhoeven, D., van Nierop, ... a000693 First citation in articleLink, Google ScholarPirkis, J., John, A., Shin, S., DelPozo-Banos, M., Arya V., ...
Tópico(s): Psychosomatic Disorders and Their Treatments
2022 - Hogrefe Verlag | Crisis
Produção Nacional
Revisado por pares
Andrea Cossarizza, Hyun‐Dong Chang, Andreas Radbruch, Mübeccel Akdiş, Immanuel Andrä, Francesco Annunziato, Petra Bächer, Vincenzo Barnaba, Luca Battistini, Wolfgang Bauer, Sabine Baumgart, Burkhard Becher, Wolfgang Beisker, Claudia Berek, Alfonso Blanco, Giovanna Borsellino, Philip E. Boulais, Ryan R. Brinkman, Martin Büscher, Dirk H. Busch, Timothy Bushnell, Xuetao Cao, Andrea Cavani, Pratip K. Chattopadhyay, Qingyu Cheng, Sue Chow, Mario Clerici, Anne Cooke, Antonio Cosma, Lorenzo Cosmi, Ana Cumano, Van Duc Dang, Derek Davies, Sara De Biasi, Genny Del Zotto, Silvia Della Bella, Paolo Dellabona, Günnur Deniz, Mark C. Dessing, Andreas Diefenbach, James P. Di Santo, Francesco Dieli, Andreas Dolf, Vera S. Donnenberg, Thomas Dörner, Götz R. A. Ehrhardt, Elmar Endl, Pablo Engel, Britta Engelhardt, Charlotte Esser, Bart Everts, Anita Dreher, Christine S. Falk, Todd A. Fehniger, Andrew Filby, Simon Fillatreau, Marie Follo, Irmgard Förster, John R. Foster, Gemma A. Foulds, Paul S. Frenette, David W. Galbraith, Natalio Garbi, Maria Dolores García‐Godoy, Jens Geginat, Kamran Ghoreschi, Lara Gibellini, Christoph Goettlinger, Carl S. Goodyear, Andrea Gori, Jane L. Grogan, Mor Gross, Andreas Grützkau, Daryl Grummitt, Jonas Hahn, Quirin Hammer, Anja E. Hauser, David L. Haviland, David W. Hedley, Guadalupe Herrera, Martin Herrmann, Falk Hiepe, Tristan Holland, Pleun Hombrink, Jessica P. Houston, Bimba F. Hoyer, Bo Huang, Christopher A. Hunter, Anna Iannone, Hans‐Martin Jäck, Beatriz Jávega, Stipan Jonjić, Kerstin Juelke, Steffen Jung, Toralf Kaiser, Tomáš Kalina, Baerbel Keller, Srijit Khan, Deborah Kienhöfer, Thomas Kroneis, Désirée Kunkel, Christian Kurts, Pia Kvistborg, Joanne Lannigan, Olivier Lantz, Anis Larbi, Salomé LeibundGut‐Landmann, Michael D. Leipold, Megan K. Levings, Virginia Litwin, Yanling Liu, Michael Lohoff, Giovanna Lombardi, Lilly Lopez, Amy E. Lovett‐Racke, Erik Lubberts, Burkhard Ludewig, Enrico Lugli, Holden T. Maecker, Glòria Martrus, Giuseppe Matarese, Christian Maueröder, Mairi McGrath, Iain B. McInnes, Henrik E. Mei, Fritz Melchers, Susanne Melzer, Dirk Mielenz, Kingston H. G. Mills, David Mirrer, Jenny Mjösberg, Jonni S. Moore, Barry Moran, Alessandro Moretta, Lorenzo Moretta, Tim R. Mosmann, Susann Müller, Werner Müller, Christian Münz, Gabriele Multhoff, Luis E. Muñoz, Kenneth M. Murphy, Toshinori Nakayama, Milena Nasi, Christine Neudörfl, John P. Nolan, Sussan Nourshargh, José‐Enrique O’Connor, Wenjun Ouyang, Annette Oxenius, Raghavendra Palankar, Isabel Panse, Pärt Peterson, Christian Peth, Jordi Pétriz, Daisy Philips, Winfried F. Pickl, Silvia Piconese, Marcello Pinti, A. Graham Pockley, Malgorzata J. Podolska, Carlo Pucillo, Sally A. Quataert, Timothy R. D. J. Radstake, Bartek Rajwa, Jonathan A. Rebhahn, Diether Recktenwald, Ester B. M. Remmerswaal, Katy Rezvani, Laura G. Rico, J. Paul Robinson, Chiara Romagnani, Anna Rubartelli, Beate Rückert, Jürgen Ruland, Shimon Sakaguchi, Francisco Sala‐de‐Oyanguren, Yvonne Samstag, Sharon Sanderson, Birgit Sawitzki, Alexander Scheffold, Matthias Schiemann, Frank A. Schildberg, Esther Schimisky, Stephan Schmid, Steffen Schmitt, Kilian Schober, Thomas Schüler, Axel Schulz, Ton N. Schumacher, Cristiano Scottà, T. Vincent Shankey, Anat Shemer, Anna Katharina Simon, Josef Špidlen, Alan M. Stall, Regina Stark, Christina Stehle, Merle Stein, Tobit Steinmetz, Hannes Stockinger, Yousuke Takahama, Attila Tárnok, Zhi‐Gang Tian, Gergely Toldi, Julia Tornack, Elisabetta Traggiai, Joe Trotter, Henning Ulrich, Marlous van der Braber, René A. W. van Lier, Marc Veldhoen, Salvador Vento‐Asturias, Paulo Vieira, David Voehringer, Hans‐Dieter Volk, Konrad von Volkmann, Ari Waisman, Rachael Walker, Michael D. Ward, Klaus Warnatz, Sarah Warth, James E. M. Watson, Carsten Watzl, Leonie Wegener, Annika Wiedemann, Jürgen Wienands, Gerald Willimsky, James B. Wing, Peter Wurst, Liping Yu, Alice Yue, Victor Wei Zhang, Yi Zhao, Susanne Ziegler, Jakob Zimmermann,
The marriage between immunology and cytometry is one of the most stable and productive in the recent history of science. A rapid search in PubMed shows that, as of July 2017, using "flow cytometry immunology" as a search term yields more than 68 000 articles, the first of which, interestingly, is not about lymphocytes. It might be stated that, after a short engagement, the exchange of the wedding rings between immunology and cytometry officially occurred when the idea to link fluorochromes to monoclonal ...
Tópico(s): T-cell and B-cell Immunology
2017 - Wiley | European Journal of Immunology