John J. Leddy, Andrea Hinds, Jeffrey C. Miecznikowski, Scott R. Darling, Jason Matuszak, John G. Baker, John Picano, Barry Willer,
Objective: To evaluate (1) systematic assessment of exercise tolerance in adolescents shortly after sport-related concussion (SRC) and (2) the prognostic utility of such assessment. Design: Prospective randomized controlled trial. Setting: University and community sports medicine centers. Participants: Adolescents with SRC (1–9 days from injury). Sixty-five were randomized and 54 completed the study (mean age 15 years, 4 days after injury). Interventions: Buffalo Concussion Treadmill Test (BCTT, n = 27) ...
Tópico(s): Injury Epidemiology and Prevention
2017 - Lippincott Williams & Wilkins | Clinical Journal of Sport Medicine
Jeffrey E. Herrick, Adam Beh, Edmundo Barrios, Ioana Bouvier, Marina Coetzee, David Dent, Emile Elias, Tomislav Hengl, Jason W. Karl, Hanspeter Liniger, John Matuszak, Jason C. Neff, L. W. Ndungu, Michael Obersteiner, Keith Shepherd, Kevin Urama, Rik van den Bosch, Nicholas P. Webb,
Abstract Massive investments in climate change mitigation and adaptation are projected during coming decades. Many of these investments will seek to modify how land is managed. The return on both types of investments can be increased through an understanding of land potential: the potential of the land to support primary production and ecosystem services, and its resilience. A Land‐Potential Knowledge System (LandPKS) is being developed and implemented to provide individual users with point‐based ...
Tópico(s): Soil Moisture and Remote Sensing
2016 - Taylor & Francis | Ecosystem health and sustainability
James Boyd, Kenneth J. Bagstad, Jane Carter Ingram, Carl D. Shapiro, Jeffery Adkins, Caitlin M. Casey, Clifford S. Duke, Pierre D. Glynn, Erica Goldman, Monica Grasso, Julie L. Hass, Justin A. Johnson, Glenn‐Marie Lange, John Matuszak, Ann Ratner Miller, Kirsten L.L. Oleson, Stephen Posner, Charles Rhodes, François Soulard, Michael Vardon, Ferdinando Villa, Brian Voigt, Scott Wentland,
Tópico(s): Economic and Environmental Valuation
2018 - Oxford University Press | BioScience
Katherine J.D. Warnell, Marc Russell, Charles Rhodes, Kenneth J. Bagstad, Lydia Olander, David J. Nowak, Rajendra Poudel, Pierre D. Glynn, Julie L. Hass, Satoshi Hirabayashi, Jane Carter Ingram, John Matuszak, Kirsten L.L. Oleson, Stephen Posner, Ferdinando Villa,
Ecosystem accounts, as formalized by the System of Environmental-Economic Accounting Experimental Ecosystem Accounts (SEEA EEA), have been compiled in a number of countries, yet there have been few attempts to develop them for the U.S. We explore the potential for U.S. ecosystem accounting by compiling ecosystem extent, condition, and ecosystem services supply and use accounts for a 10-state region in the Southeast. The pilot accounts address air quality, water quality, biodiversity, carbon storage, ...
Tópico(s): Conservation, Biodiversity, and Resource Management
2020 - Elsevier BV | Ecosystem Services
Mehdi P. Heris, Kenneth J. Bagstad, Charles Rhodes, Austin Troy, Ariane Middel, Krissy G. Hopkins, John Matuszak,
In this study, we develop urban ecosystem accounts in the U.S., using the System of Environmental-Economic Accounting Experimental Ecosystem Accounting (SEEA EEA) framework. Most ecosystem accounts focus on regional and national scales, which are appropriate for many ecosystem services. However, ecosystems provide substantial services in cities, improving quality of life and contributing to resiliency for substantial parts of the population. Our models estimate energy savings for indoor cooling resulting ...
Tópico(s): Urban Heat Island Mitigation
2021 - Elsevier BV | Ecosystem Services
Kenneth J. Bagstad, Jane Carter Ingram, Carl D. Shapiro, Alessandra La Notte, Joachim Maes, Sara Vallecillo, Caitlin M. Casey, Pierre D. Glynn, Mehdi P. Heris, Justin A. Johnson, Chris Lauer, John Matuszak, Kirsten L.L. Oleson, Stephen Posner, Charles Rhodes, Brian Voigt,
The United States and European Union (EU) face common challenges in managing natural capital and balancing conservation and resource use with consumption of other forms of capital. This paper synthesizes findings from 11 individual application papers from a special issue of Ecosystem Services on natural capital accounting (NCA) and their application to the public and private sectors in the EU and U.S. NCA is inherently a data-integration centered exercise, aiming to draw new insights by realigning ...
Tópico(s): Climate Change Policy and Economics
2021 - Elsevier BV | Ecosystem Services
Daniel J. Mollura, John A. Carrino, Diane L. Matuszak, Zaruhi R. Mnatsakanyan, John Eng, Protagoras N. Cutchis, Steven M. Babin, Carol Sniegoski, Joseph S. Lombardo,
Radiology and public health have an emerging opportunity to collaborate, in which radiology’s vast supply of imaging data can be integrated into public health information systems for epidemiologic assessments and responses to population health problems. Fueling the linkage of radiology and public health include (i) the transition from analog film to digital formats, enabling flexible use of radiologic data; (ii) radiology’s role in imaging across nearly all medical and surgical subspecialties, which ...
Tópico(s): Electronic Health Records Systems
2008 - Elsevier BV | Journal of the American College of Radiology
William E. Fry, Stephen B. Goodwin, John M. Matuszak, Linda J. Spielman, Michael G. Milgroom, A. Drenth,
Our understanding of the population genetics of Phytophthora infestans has increased dramatically during the past decade. In addition to satisfying scientific curiosity, we expect that this understanding will lead to im provements in tomato and potato late blight management. We briefly describe the classical population biology/genetics of P. in Jestans to provide context for this review. Potato late blight caused by P. infestans was probably first observed outside of central Mexico in 1842 in ...
Tópico(s): Plant Pathogens and Fungal Diseases
1992 - Annual Reviews | Annual Review of Phytopathology
Niklaus J. Grünwald, W.G. Flier, Anne Sturbaum, Edith Garay, Trudy B. M. van den Bosch, Christine D. Smart, John M. Matuszak, Héctor Lozoya-Saldaña, L. J. Turkensteen, W. E. Fry,
We tested the hypothesis that the population of Phytophthora infestans in the Toluca valley region is genetically differentiated according to habitat. Isolates were sampled in three habitats from (i) wild Solanum spp. (WILD), (ii) land-race varieties in low-input production systems (RURAL), and (iii) modern cultivars in high-input agriculture (VALLEY). Isolates were sampled in 1988-89 (n= 179) and in 1997-98 (n= 389). In both sampling periods, the greatest genetic diversity was observed in RURAL and VALLEY ...
Tópico(s): Cocoa and Sweet Potato Agronomy
2001 - American Phytopathological Society | Phytopathology
Richard D. E. Burton, Kenneth P. Matuszak, Clifford H. Watson, John R. Eyler,
Fourier transform ion cyclotron resonance mass spectrometry has been found to produce reliable exact mass measurements using two different internal calibration methods. For these measurements, electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI) were utilized both individually and in tandem. For internal calibration with a co-dissolved polyethylene glycol standard, measurements of 41 compounds resulted in an average absolute mass determination error of 0.7 ppm, with ...
Tópico(s): Ion-surface interactions and analysis
1999 - American Chemical Society | Journal of the American Society for Mass Spectrometry
Leah M. Williams, Lauren E. Fuess, Joseph J. Brennan, Katelyn M. Mansfield, Erick Salas-Rodriguez, Julianne Welsh, Jake Awtry, Sarah Banic, Cecilia Chacko, Aarthia Chezian, Donovan Dowers, Felicia Estrada, Yu‐Hsuan Hsieh, Jiawen Kang, Wanwen Li, Zoe X. Malchiodi, John Malinowski, Sean J. Matuszak, Thomas McTigue, David Mueller, Brian Nguyen, Michelle Nguyen, Phuong Nguyen, Sinead Nguyen, Ndidi Njoku, Khusbu Patel, William R. Pellegrini, Tessa Pliakas, Deena Qadir, Emma Ryan, Alex Schiffer, Amber Thiel, Sarah A. Yunes, Kathryn E. Spilios, Jorge H. Pinzón, Laura D. Mydlarz, Thomas D. Gilmore,
Herein, we characterize the Toll-like receptor (TLR)-to-NF-κB innate immune pathway of Orbicella faveolata (Of), which is an ecologically important, disease-susceptible, reef-building coral. As compared to human TLRs, the intracellular TIR domain of Of-TLR is most similar to TLR4, and it can interact in vitro with the human TLR4 adapter MYD88. Treatment of O. faveolata tissue with lipopolysaccharide, a ligand for mammalian TLR4, resulted in gene expression changes consistent with NF-κB pathway mobilization. ...
Tópico(s): Immune Response and Inflammation
2017 - Elsevier BV | Developmental & Comparative Immunology
Stanley A. Herring, W. Ben Kibler, Margot Putukian, Gary S. Solomon, Lori A. Boyajian-O’Neill, Katherine L. Dec, R. Robert Franks, Peter A. Indelicato, Cynthia R. LaBella, John J. Leddy, Jason Matuszak, E. Barry McDonough, Francis O’Connor, Karen M. Sutton,
Selected Issues in Sport-Related Concussion (SRC|Mild Traumatic Brain Injury) for the Team Physician: A Consensus Statement is title 22 in a series of annual consensus documents written for the practicing team physician. This document provides an overview of selected medical issues important to team physicians who are responsible for athletes with sports-related concussion (SRC). This statement was developed by the Team Physician Consensus Conference (TPCC), an annual project-based alliance of six ...
Tópico(s): Trauma and Emergency Care Studies
2021 - BMJ | British Journal of Sports Medicine
Jason Matuszak, Jennifer McVige, Jacob I. McPherson, Barry Willer, John J. Leddy,
Context: With heightened awareness of concussion, there is a need to assess and manage the concussed patient in a consistent manner. Unfortunately, concussion physical examination has not been standardized or supported by evidence. Important questions remain about the physical examination. Evidence Acquisition: Review of ClinicalKey, Cochrane, MEDLINE, and PubMed prior to July 2015 was performed using search terms, including concussion, mTBI, physical examination, mental status, cranial nerves, ...
Tópico(s): Traumatic Ocular and Foreign Body Injuries
2016 - SAGE Publishing | Sports Health A Multidisciplinary Approach
John J. Leddy, John G. Baker, Asim Merchant, John Picano, Daniel P. Gaile, Jason Matuszak, Barry Willer,
To compare symptoms in patients with physiologic postconcussion disorder (PCD) versus cervicogenic/vestibular PCD. We hypothesized that most symptoms would not be equivalent. In particular, we hypothesized that cognitive symptoms would be more often associated with physiologic PCD.Retrospective review of symptom reports from patients who completed a 22-item symptom questionnaire.University-based concussion clinic.Convenience sample of 128 patients who had symptoms after head injury for more than ...
Tópico(s): Automotive and Human Injury Biomechanics
2014 - Lippincott Williams & Wilkins | Clinical Journal of Sport Medicine
Christina Tsien, Stephanie L. Pugh, Adam P. Dicker, Jeffrey J. Raizer, M.M. Matuszak, Enrico C. Lallana, Jiayi Huang, Özer Algan, Nimisha Deb, Lorraine Portelance, John L. Villano, John Hamm, Kevin Oh, Arif N. Ali, Michelle M. Kim, Scott Lindhorst, Minesh P. Mehta,
PURPOSE To assess whether reirradiation (re-RT) and concurrent bevacizumab (BEV) improve overall survival (OS) and/or progression-free survival (PFS), compared with BEV alone in recurrent glioblastoma (GBM). The primary objective was OS, and secondary objectives included PFS, response rate, and treatment adverse events (AEs) including delayed CNS toxicities. METHODS NRG Oncology/RTOG1205 is a prospective, phase II, randomized trial of re-RT and BEV versus BEV alone. Stratification factors included age, ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2022 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Weikuan Gu, Linda J. Spielman, John M. Matuszak, James R. Aist, Carol J. Bayles, William E. Fry,
The nuclear DNA contents of 145 isolates of Phytophthora infestans from the central highlands of Mexico (the centre of origin of this oomycete), northwestern Mexico, and northeastern Mexico were measured by quantifying the fluorescence from nuclei stained with 4,6-diamidino-2-phenyl-indole (DAPI). Isolates were collected over several different years. Isolates that had been repeatedly subcultured tended to have higher DNA contents than had isolates from storage. Therefore, the DNA contents were measured ...
Tópico(s): Yeasts and Rust Fungi Studies
1993 - Cambridge University Press | Mycological Research
Tópico(s): Historical Studies on Reproduction, Gender, Health, and Societal Changes
1991 - British Society for the History of Pharmacy | Revue d histoire de la pharmacie
Christina Tsien, S. Pugh, Adam P. Dicker, Jeffrey J. Raizer, M.M. Matuszak, Enrico C. Lallana, Jiayi Huang, Özer Algan, N. Jane Taylor, Lorraine Portelance, John L. Villano, John Hamm, Kevin Oh, Arif N. Ali, M.M. Kim, Scott Lindhorst, Minesh P. Mehta,
RTOG 1205 is the first, multi-institutional, prospective randomized phase II trial to evaluate the safety and efficacy of re-irradiation for recurrent glioblastoma using modern radiation therapy (RT) techniques. We report clinical outcomes and results of the RT plan quality review. Eligible patients (pts) were randomized 1:1 to hypofractionated reirradiation (HFRT, 35 Gy in 10 fractions) with concurrent bevacizumab (BEV) IV 10 mg/kg q2 wks vs. BEV alone. Primary endpoint was improved median survival ...
Tópico(s): Brain Metastases and Treatment
2019 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics
Christina Tsien, Stephanie L. Pugh, Adam P. Dicker, Jeffrey J. Raizer, M.M. Matuszak, Enrico C. Lallana, Jiayi Huang, Özer Algan, Nicholas F. Taylor, Lorraine Portelance, John L. Villano, John Hamm, Kevin Oh, Arif N. Ali, Michelle Kim, Scott Lindhorst, Minesh P. Mehta,
Abstract This study sought to determine whether re-irradiation (ReRT) and concurrent bevacizumab (BEV) improves overall survival (OS) compared to BEV alone in recurrent glioblastoma (GBM). Patients (pts) were randomized 1:1 to ReRT (35 Gy/10 fractions) plus BEV (IV 10 mg/kg q2 wks) vs. BEV alone. With 160 pts, there was 80% power to detect a 31% reduction in death hazard for BEV+RT at a one-sided significance level of 0.10 using a log rank test. OS and PFS were estimated by Kaplan-Meier and HRs estimated ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2019 - Oxford University Press | Neuro-Oncology
Charles S. Mayo, Michelle Mierzwa, Jean M. Moran, M.M. Matuszak, Joel R. Wilkie, Grace Sun, John Yao, Grant Weyburn, Carlos Anderson, Dawn Owen, Arvind Rao,
We combined clinical practice changes, standardizations, and technology to automate aggregation, integration, and harmonization of comprehensive patient data from the multiple source systems used in clinical practice into a big data analytics resource system (BDARS). We then developed novel artificial intelligence algorithms, coupled with the BDARS, to identify structure dose volume histograms (DVH) metrics associated with dysphagia.From the BDARS harmonized data of ≥22,000 patients, we identified ...
Tópico(s): Esophageal and GI Pathology
2020 - Elsevier BV | Advances in Radiation Oncology
Stanley A. Herring, W. Ben Kibler, Margot Putukian, Gary S. Solomon, Lori A. Boyajian-O’Neill, Katherine L. Dec, R. Robert Franks, Peter A. Indelicato, Cynthia R. LaBella, John J. Leddy, Jason Matuszak, E. Barry McDonough, Francis G. O’Connor, Karen M. Sutton,
Abstract Selected Issues in Sport-Related Concussion (SRC | Mild Traumatic Brain Injury) for the Team Physician: A Consensus Statement is title 22 in a series of annual consensus articles written for the practicing team physician. This document provides an overview of select medical issues important to team physicians who are responsible for athletes with sports-related concussion (SRC). This statement was developed by the Team Physician Consensus Conference (TPCC), an annual project-based alliance of ...
Tópico(s): Trauma and Emergency Care Studies
2021 - Lippincott Williams & Wilkins | Current Sports Medicine Reports
Edward E. Smissman, R. A. Robinson, John B. Carr, Alice Jean Matuszak,
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and rearrangement of 5-phenyl-7-methoxy-2,4,9-trioxo-1,3-diazabicyclo[3.3.1]nonaneEdward E. Smissman, Robert A. Robinson, John B. Carr, and Alice J. MatuszakCite this: J. Org. Chem. 1970, 35, 11, 3821–3822Publication Date (Print):November 1, 1970Publication History Published online1 May 2002Published inissue 1 November 1970https://pubs.acs.org/doi/10.1021/jo00836a053https://doi.org/10.1021/jo00836a053research-articleACS PublicationsRequest reuse ...
Tópico(s): Oxidative Organic Chemistry Reactions
1970 - American Chemical Society | The Journal of Organic Chemistry
Charles S. Mayo, John Yao, Avraham Eisbruch, James M. Balter, Dale W. Litzenberg, M.M. Matuszak, Marc L. Kessler, Grant Weyburn, Carlos Anderson, Dawn Owen, Will Jackson, R. Ten Haken,
To develop statistical dose-volume histogram (DVH)-based metrics and a visualization method to quantify the comparison of treatment plans with historical experience and among different institutions.The descriptive statistical summary (ie, median, first and third quartiles, and 95% confidence intervals) of volume-normalized DVH curve sets of past experiences was visualized through the creation of statistical DVH plots. Detailed distribution parameters were calculated and stored in JavaScript Object ...
Tópico(s): Advances in Oncology and Radiotherapy
2017 - Elsevier BV | Advances in Radiation Oncology
Alice Jean Matuszak, John E. Taylor,
Tópico(s): Phosphodiesterase function and regulation
1977 - Elsevier BV | American Journal of Pharmaceutical Education
Katherine J.D. Warnell, Marc Russell, Charles Rhodes, Kenneth J. Bagstad, Lydia Olander, David J. Nowak, Rajendra Poudel, Pierre D. Glynn, Julie L. Hass, Satoshi Hirabayashi, Jane Carter Ingram, John Matuszak, Kirsten L.L. Oleson, Stephen Posner, Ferdinando Villa,
Tópico(s): Land Use and Ecosystem Services
2020 - Elsevier BV | Ecosystem Services
E. Vicente, Arezoo Modiri, John Kipritidis, A Hagan, Kun‐Chang Yu, Henky Wibowo, Yulong Yan, Dawn Owen, M.M. Matuszak, Pranshu Mohindra, Robert Timmerman, Amit Sawant,
Recent changes to the guidelines for screening and early diagnosis of lung cancer have increased the interest in preserving post-radiotherapy lung function. Current investigational approaches are based on spatially mapping functional regions and generating regional avoidance plans that preferentially spare highly ventilated/perfused lung. A potentially critical, yet overlooked, aspect of functional avoidance is radiation injury to peripheral airways, which serve as gas conduits to and from functional ...
Tópico(s): Effects of Radiation Exposure
2020 - IOP Publishing | Physics in Medicine and Biology
Rajiv Jain, Kelley W. Marshall, John J. Leddy, Jason Matuszak, Anthony Surace, Griffin T. Spatorico, Mohammad N. Haider,
Tópico(s): Cardiac Arrest and Resuscitation
2025 - Lippincott Williams & Wilkins | Clinical Journal of Sport Medicine
E Jaworski, Michelle Mierzwa, K.A. Vineberg, John Yao, Jennifer Shah, Caitlin Schonewolf, Dale W. Litzenberg, Laila A. Gharzai, M.M. Matuszak, Kelly C. Paradis, Ashley Dougherty, Pamela Burger, Daniel Tatro, G Arnould, Jean M. Moran, Choonik Lee, Avraham Eisbruch, Charles S. Mayo,
Head and neck (HN) radiation (RT) treatment planning is complex and resource intensive. Deviations and inconsistent plan quality significantly affect clinical outcomes. We sought to develop a novel automated virtual integrative (AVI) knowledge-based planning application to reduce planning time, increase consistency, and improve baseline quality.An in-house write-enabled script was developed from a library of 668 previously treated HN RT plans. Prospective hazard analysis was performed, and mitigation ...
Tópico(s): Head and Neck Surgical Oncology
2022 - Elsevier BV | Advances in Radiation Oncology
E. Vicente, Arezoo Modiri, John Kipritidis, Kun‐Chang Yu, Kai Sun, J. Cammin, Arun Gopal, Jingzhu Xu, Sina Mossahebi, A Hagan, Yulong Yan, Daniel Rockwell Owen, Pranshu Mohindra, M.M. Matuszak, Robert Timmerman, Amit Sawant,
Functional lung avoidance (FLA) radiation therapy (RT) aims to minimize post-RT pulmonary toxicity by preferentially avoiding dose to high-functioning lung (HFL) regions. A common limitation is that FLA approaches do not consider the conducting architecture for gas exchange. We previously proposed the functionally weighted airway sparing (FWAS) method to spare airways connected to HFL regions, showing that it is possible to substantially reduce risk of radiation-induced airway injury. Here, we compare ...
Tópico(s): Effects of Radiation Exposure
2022 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics
Reviewed by: Amerika, or The Disappearance Steve Matuszak Amerika, or The Disappearance. Originally produced in association with the American Repertory Theatre with text by Gideon Lester. Adapted for the Theatre de la Jeune Luneby Steven Epp and Dominique Serrand. Directed by Dominique Serrand. Theatre de la Jeune Lune, Minneapolis, MN. 02032006. In the Theatre de la Jeune Lune's adaptation of Franz Kafka's unfinished novel Der Verschollene, the function of the word "disappearance" in the title underscores ...
2006 - Johns Hopkins University Press | Theatre Journal