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Artigo Acesso aberto Revisado por pares

David Fuentes, J. Tinsley Oden, Kenneth R. Diller, John D. Hazle, Andrew M. Elliott, Ajoy Prasad Shetty, R. Jason Stafford,

An adaptive feedback control system is presented which employs a computational model of bioheat transfer in living tissue to guide, in real-time, laser treatments of prostate cancer monitored by magnetic resonance thermal imaging. The system is built on what can be referred to as cyberinfrastructure—a complex structure of high-speed network, large-scale parallel computing devices, laser optics, imaging, visualizations, inverse-analysis algorithms, mesh generation, and control systems that guide ...

Tópico(s): Infrared Thermography in Medicine

2009 - Springer Science+Business Media | Annals of Biomedical Engineering

Artigo Acesso aberto Revisado por pares

J. Tinsley Oden, Kenneth R. Diller, Chandrajit Bajaj, James C. Browne, John D. Hazle, Ivo Babuška, J. M. Bass, L. Biduat, Leszek Demkowicz, Andrew M. Elliott, Yonggang Feng, David Fuentes, Serge Prudhomme, M. Nichole Rylander, R. Jason Stafford, Yongjie Zhang,

Abstract Elevating the temperature of cancerous cells is known to increase their susceptibility to subsequent radiation or chemotherapy treatments, and in the case in which a tumor exists as a well‐defined region, higher intensity heat sources may be used to ablate the tissue. These facts are the basis for hyperthermia based cancer treatments. Of the many available modalities for delivering the heat source, the application of a laser heat source under the guidance of real‐time treatment data has ...

Tópico(s): Advanced X-ray Imaging Techniques

2007 - Wiley | Numerical Methods for Partial Differential Equations

Capítulo de livro Acesso aberto Revisado por pares

J. Tinsley Oden, Kenneth R. Diller, Chandrajit Bajaj, James C. Browne, John D. Hazle, Ivo Babuška, J. M. Bass, Leszek Demkowicz, Yonggang Feng, David Fuentes, Serge Prudhomme, M. Nichole Rylander, R. Jason Stafford, Yongjie Zhang,

The goal of this project is to develop a dynamic data-driven planning and control system for laser treatment of cancer. The research includes (1) development of a general mathematical framework and a family of mathematical and computational models of bio-heat transfer, tissue damage, and tumor viability, (2) dynamic calibration, verification and validation processes based on laboratory and clinical data and simulated response, and (3) design of effective thermo-therapeutic protocols using model predictions. ...

Tópico(s): Thermoelastic and Magnetoelastic Phenomena

2006 - Springer Science+Business Media | Lecture notes in computer science

Artigo Revisado por pares

John W. Leonard,

... 295-297 Comment Discussion of papers†‡ by J. Tinsley Oden John W. Leonard, John W. Leonard Bell Aerospace Company, ... more papers by this author John W. Leonard, John W. Leonard Bell Aerospace Company, Division of Textron, Buffalo, New YorkSearch for more papers by this author First published: April/June 1970 https://doi.org/10.1002/nme.1620020215 † J. Tinsley Oden. ‘A general theory of finite elements, I. Topological ...

Tópico(s): Structural Analysis and Optimization

1970 - Wiley | International Journal for Numerical Methods in Engineering

Capítulo de livro Acesso aberto Revisado por pares

Chandrajit Bajaj, J. Tinsley Oden, Kenneth R. Diller, James C. Browne, John D. Hazle, Ivo Babuška, J. M. Bass, Luc Bidaut, Leszek Demkowicz, Andrew M. Elliott, Yonggang Feng, David Fuentes, Bongjune Kwon, Serge Prudhomme, R. Jason Stafford, Yongjie Zhang,

Hyperthermia based cancer treatments are used to increase the susceptibility of cancerous tissue to subsequent radiation or chemotherapy treatments, and in the case in which a tumor exists as a well-defined region, higher intensity heat sources may be used to ablate the tissue. Utilizing the guidance of real-time treatment data while applying a laser heat source has the potential to provide unprecedented control over the outcome of the treatment process [6,12]. The goals of this work are to provide ...

Tópico(s): Infrared Thermography in Medicine

2007 - Springer Science+Business Media | Lecture notes in computer science

Artigo

J. Tinsley Oden, John R. O’Leary,

Abstract We discuss here several results on the convergence of finite element methods for problems with corners and cracks. We also derive some a priori estimates for a certain class of hybrid finite elements.

Tópico(s): Contact Mechanics and Variational Inequalities

1978 - Taylor & Francis | Journal of Structural Mechanics

Artigo Acesso aberto Revisado por pares

Thomas J.R. Hughes, J. Tinsley Oden, Manolis Papadrakakis,

2004 - Elsevier BV | Computer Methods in Applied Mechanics and Engineering

Artigo Acesso aberto Revisado por pares

James D. Murphy, J. Tinsley Oden, J. Uzan, John P. Einck, Vitali Moiseenko, G. Gagliardi,

Cardiac morbidity and mortality represents a major concern for women with left-sided breast cancer receiving adjuvant radiation. Substantial research has quantified and studied this risk, and consensus guidelines from QUANTEC recommended keeping the volume of heart receiving 25 Gy (V25) <10% to reduce the risk of cardiac mortality <1%. The purpose of this study was to determine QUANTEC compliance, and to determine whether following QUANTEC guidelines in fact reduces the risk of predicted cardiac mortality ...

Tópico(s): Radiation Dose and Imaging

2015 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics

Artigo Revisado por pares

Mark Ainsworth, J. Tinsley Oden, C. Y. Lee,

Abstract Local a posteriori error estimators for finite element approximation of variational inequalities are derived. These are shown to provide upper bounds on the discretization error. Numerical examples are given illustrating the theoretical results. © 1993 John Wiley & Sons, Inc.

Tópico(s): Numerical methods in engineering

1993 - Wiley | Numerical Methods for Partial Differential Equations

Artigo Revisado por pares

J. Tinsley Oden, Serge Prudhomme,

We present a new approach to deliver reliable approximations of the norm of the residuals resulting from finite element solutions to the Stokes and Oseen equations. The method is based upon a global solve in a bubble space using iterative techniques. This provides an alternative to the classical equilibrated element residual methods for which it is necessary to construct proper boundary conditions for each local problem. The method is first used to develop a global a posteriori error estimator. ...

Tópico(s): Model Reduction and Neural Networks

1999 - Wiley | International Journal for Numerical Methods in Fluids

Artigo Revisado por pares

Carlos Baumann, J. Tinsley Oden,

This paper introduces a new method for the solution of the Euler and Navier–Stokes equations, which is based on the application of a recently developed discontinuous Galerkin technique to obtain a compact, higher-order accurate and stable solver. The method involves a weak imposition of continuity conditions on the state variables and on inviscid and diffusive fluxes across inter-element and domain boundaries. Within each element the field variables are approximated using polynomial expansions with ...

Tópico(s): Model Reduction and Neural Networks

1999 - Wiley | International Journal for Numerical Methods in Fluids

Artigo Revisado por pares

C. Armando Duarte, J. Tinsley Oden,

A new methodology to build discrete models of boundary-value problems is presented. The h-p cloud method is applicable to arbitrary domains and employs only a scattered set of nodes to build approximate solutions to BVPs. This new method uses radial basis functions of varying size of supports and with polynomial-reproducing properties of arbitrary order. The approximating properties of the h-p cloud functions are investigated in this article and several theorems concerning these properties are presented. ...

Tópico(s): Fluid Dynamics Simulations and Interactions

1996 - Wiley | Numerical Methods for Partial Differential Equations

Artigo Revisado por pares

Serge Prudhomme, J. Tinsley Oden, T.A. Westermann, J. M. Bass, M. E. Botkin,

Abstract This work presents an extension of the goal‐oriented error estimation technique to the engineering analysis of three‐dimensional linear elastic bodies. In the series of examples shown, the errors are estimated with respect to local displacement and stress components. The paper also introduces novel means to compute lower bounds on the error in the energy norm based on a cost‐effective postprocessing of the upper bound error estimates. The numerical results indicate that the method can be ...

Tópico(s): Model Reduction and Neural Networks

2003 - Wiley | International Journal for Numerical Methods in Engineering

Artigo Acesso aberto Revisado por pares

Carlos Baumann, J. Tinsley Oden,

We present an adaptive-order discontinuous Galerkin technique that produces a compact, higher-order-accurate, and stable solver. The method involves a weak approximation of the conservation equations and a weak imposition of the Rankine–Hugoniot jump conditions across interelement and domain boundaries. This discontinuous Galerkin approximation is conservative and permits the use of different polynomial order in each subdomain according to the local smoothness of the solution. Moreover, the compactness ...

Tópico(s): Fluid Dynamics and Turbulent Flows

2000 - Wiley | International Journal for Numerical Methods in Engineering

Artigo Revisado por pares

Andrea Hawkins‐Daarud, Kristoffer G. van der Zee, J. Tinsley Oden,

SUMMARY In this paper, we develop a thermodynamically consistent four‐species model of tumor growth on the basis of the continuum theory of mixtures. Unique to this model is the incorporation of nutrient within the mixture as opposed to being modeled with an auxiliary reaction‐diffusion equation. The formulation involves systems of highly nonlinear partial differential equations of surface effects through diffuse‐interface models. A mixed finite element spatial discretization is developed and implemented ...

Tópico(s): Solidification and crystal growth phenomena

2011 - Wiley | International Journal for Numerical Methods in Biomedical Engineering

Artigo Revisado por pares

J. Tinsley Oden, Serge Prudhomme,

Abstract The idea of adaptive control of modeling error is expanded to include ideas of statistical calibration, validation, and uncertainty quantification. Copyright © 2010 John Wiley & Sons, Ltd.

Tópico(s): Scientific Measurement and Uncertainty Evaluation

2010 - Wiley | International Journal for Numerical Methods in Engineering

Artigo Revisado por pares

Ludovic Chamoin, Serge Prudhomme, Hachmi Ben Dhia, Tinsley Oden,

Abstract The main objective of this work is to identify spurious effects and propose a corrective method when coupling a particle model involving long–range interaction potentials with a first gradient homogenized model using the Arlequin framework. The most significant spurious effects are generally created by the so‐called ghost forces that arise in coupling methods based on the minimization of a global energy functional. They depend as well on the coupling formulation itself, on the notion of ...

Tópico(s): Advanced Numerical Methods in Computational Mathematics

2010 - Wiley | International Journal for Numerical Methods in Engineering

Artigo Revisado por pares

Ernesto E. Prudencio, Paul T. Bauman, Danial Faghihi, K. Ravi‐Chandar, J. Tinsley Oden,

Summary In the present study, a general dynamic data‐driven application system (DDDAS) is developed for real‐time monitoring of damage in composite materials using methods and models that account for uncertainty in experimental data, model parameters, and in the selection of the model itself. The methodology involves (i) data data from uniaxial tensile experiments conducted on a composite material; (ii) continuum damage mechanics based material constitutive models; (iii) a Bayesian framework for uncertainty ...

Tópico(s): Fault Detection and Control Systems

2014 - Wiley | International Journal for Numerical Methods in Engineering

Artigo Acesso aberto Revisado por pares

Thomas J.R. Hughes, J. Tinsley Oden, Manolis Papadrakakis,

2006 - Elsevier BV | Computer Methods in Applied Mechanics and Engineering

Artigo

Serge Prudhomme, J. Tinsley Oden,

Abstract This paper describes a strategy to control errors in finite element approximations of the time‐dependent incompressible Navier–Stokes equations. The approach involves estimating the errors due to the discretization in space, using information from the residuals in the momentum and continuity equations. Following a numerical stability analysis of channel flows past a cylinder, it is concluded that the errors due to the residual in the continuity equation should be carefully controlled since ...

Tópico(s): Model Reduction and Neural Networks

2002 - Wiley | Communications in Numerical Methods in Engineering

Artigo Acesso aberto Revisado por pares

Dr Taylor, John Argyris, Roger L. Clough, James M. Douglas, R Gallagher, Thomas E. Hughes, Alec Duncan Mitchell, J. Tinsley Oden, Kyungho Park, Ian Smith, R Taylor, C.W. Trowbridge, Geoffrey Warburton, P. Bettess, Ing Gloudeman,

International Journal for Numerical Methods in EngineeringVolume 17, Issue 6 p. 951-956 AnnouncementFree Access Announcements First published: June 1981 https://doi.org/10.1002/nme.1620170611AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions ...

Tópico(s): Advanced Numerical Methods in Computational Mathematics

1981 - Wiley | International Journal for Numerical Methods in Engineering

Artigo Revisado por pares

J. Tinsley Oden, Yusheng Feng, Serge Prudhomme,

We describe in this paper an algebraic technique for estimating local and pollution errors in finite element approximations of Stokesian flows. © 1998 John Wiley & Sons, Ltd.

Tópico(s): Computational Fluid Dynamics and Aerodynamics

1998 - Wiley | International Journal for Numerical Methods in Fluids

Paratexto Acesso aberto Brasil Produção Nacional Revisado por pares

Mark Ainsworth, M.H. Aliabadi, F. Armero, Ferdinando Auricchio, Klaus‐Jürgen Bathe, Z. P. Bažant, David J. Benson, Mark A. Bradford, Alberto Cardona, J Chen, Francisco Chinesta, Alain Combescure, Álvaro L. G. A. Coutinho, John E. Dolbow, Carlos A. Felippa, P Frey, Dan Givoli, Rodolfo E. Haber, Antonio Huerta, Thomas J.R. Hughes, G. Hulbert, Sergio R. Idelsohn, Kazuo Kashiyama, Michał Kleiber, Tod A. Laursen, X Li, Gang Liu, Wei Liu, Nicolas Moës, Shushi Nishiwaki, J. Tinsley Oden, Roger Ohayon, J. Oliver, Eugenio Oñate, Miguel Ortiz, Kyungho Park, J. Peraire, Jean‐Philippe Ponthot, Jessica Reddy, Kenneth Runesson, Bernhard A. Schrefler, Mark S. Shephard, Ole Sigmund, Paul Steinmann, Kumar K. Tamma, Robert L. Taylor, Wolfgang A. Wall, Barbara Wohlmuth, Peter Wriggers, L.C. Wrobel, Genki YAGAWA, Nicholas Zabaras, Tarek I. Zohdi,

The International Journal for Numerical Methods in Engineering publishes original papers describing significant, novel developments in numerical methods that are applicable to engineering problems.The Journal is known for welcoming contributions in a wide range of areas in computational engineering, including computational issues in model reduction, uncertainty quantification, verification and validation, inverse analysis and stochastic methods, optimisation, element technology, solution techniques ...

2022 - Wiley | International Journal for Numerical Methods in Engineering

Paratexto Acesso aberto Revisado por pares

Mark Ainsworth, M.H. Aliabadi, F. Armero, Ferdinando Auricchio, Klaus‐Jürgen Bathe, Z. P. Bažant, D. Woodrow Benson, Michael J. Bradford, Albert Cardona, Jun Chen, F. Chinesta, Alain Combescure, Álvaro L. G. A. Coutinho, John E. Dolbow, Carlos A. Felippa, P Frey, Dan Givoli, Rodolfo E. Haber, A Huerta, Thomas J.R. Hughes, G. Hulbert, Sergio R. Idelsohn, Kazuo Kashiyama, Michał Kleiber, Thomas Munk Laursen, Zheng‐Xiang Li, Gang Liu, W M Liu, Nicolas Moës, Shushi Nishiwaki, J. Tinsley Oden, Roger Ohayon, J. Oliver, Eugenio Oñate, M.A. Ortiz, Kyungho Park, J Peraire, Jean‐Philippe Ponthot, Janardan K. Reddy, K Runesson, Bernhard A. Schrefler, Mark Shephard, Ole Sigmund, Paul Steinmann, Kumar K. Tamma, Robert L. Taylor, Wolfgang A. Wall, Barbara Wohlmuth, Peter Wriggers, L.C. Wrobel, Genki YAGAWA, N Zabaras, Tarek I. Zohdi,

The International Journal for Numerical Methods in Engineering publishes original papers describing significant, novel developments in numerical methods that are applicable to engineering problems.The Journal is known for welcoming contributions in a wide range of areas in computational engineering, including computational issues in model reduction, uncertainty quantification, verification and validation, inverse analysis and stochastic methods, optimisation, element technology, solution techniques ...

Tópico(s): Structural mechanics and materials

2023 - Wiley | International Journal for Numerical Methods in Engineering

Artigo Revisado por pares

Carlos Baumann, J. Tinsley Oden,

We present an adaptive-order discontinuous Galerkin technique that produces a compact, higher-order-accurate, and stable solver. The method involves a weak approximation of the conservation equations and a weak imposition of the Rankine–Hugoniot jump conditions across interelement and domain boundaries. This discontinuous Galerkin approximation is conservative and permits the use of different polynomial order in each subdomain according to the local smoothness of the solution. Moreover, the compactness ...

Tópico(s): Numerical methods for differential equations

2000 - Wiley | International Journal for Numerical Methods in Engineering

Artigo

Surya P. Rednam, M. Scheurer, Adekunle Adesina, Clara Bik‐San Lau, Melih Okçu, J. Deatrick, Susan K. Ogle, Michele Fisher, Lolwa Barakat, Thomas Hardie, Y. Li, Jill P. Ginsberg, M. Ben-Arush, Elena Krivoy, Richard R. Rosenkranz, M. Peretz-Nahum, R. J. Brown, John M. Love, D. Warburton, William H. McBride, Stefan Blüml, Shane T. Mueller, Katherine Sear, Nancy K. Hills, N. Chettout, Shervin Afghani, Lily Q. Lew, E. Tolentino, D. Haas-Kogan, Heather J. Fullerton, W. Reddick, S. Palmer, John O. Glass, Y. Li, Robert J. Ogg, Amar Gajjar, Ayman Omar, Stephanie M. Perkins, Eric T. Shinohara, Dragan Špoljarić, J. Isenberg, Melanie D. Whittington, Marnie Hauff, Allison A. King, Kristin Litzelman, Estelle Barker, Kristine Catrine, Diane Puccetti, Peggy Possin, Whitney P. Witt, C. Mallucci, Ram Kumar, Barry Pizer, David Williams, Benedetta Pettorini, J. Piscione, E. Bouffet, Iffat Shams, Abhaya V. Kulkarni, Tiina Remes, Arja Harila‐Saari, Maria Suo‐Palosaari, Pekka Arikoski, Pekka Riikonen, Anna Sutela, P. Koskenkorva, Marja Ojaniemi, Heikki Rantala, C. J. Campen, David Ashby, P. G. Fisher, Michelle Monje, Abhaya V. Kulkarni, J. Piscione, Iffat Shams, E. Bouffet, Hideki Nakamura, Keishi Makino, S. Yano, J.-i. Kuratsu, Filip Jadrijević-Cvrlje, Maja Batinica, H. Toledano, Tammy Hoffman, Y. Ezer-Cohen, Shalom Michowiz, Isaac Yaniv, I. J. Cohen, I. Adler, Samuel Mindel, Mahalakshmi Gopalakrishnamoorthy, Dawn E. Saunders, Mark N. Gaze, H. Spoudeas, Virginie Kieffer, Georges Dellatolas, Mathilde Chevignard, S. Puget, F. Dhermain, Jacques Grill, C. Dufour, Richard Muir, Alan J. Hunter, A. Latchman, Olaf Kraus de Camargo, Katrin Scheinemann, N. K. Dhir, W. Zaky, Toska J. Zomorodian, Ken Wong, Girish Dhall, Margaret E. Macy, Carlo di Lauro, Philip Zeitler, Nicholas K. Foreman, A. Liu, Monika Chocholous, Philippe Dodier, A. Peyrl, K. Dieckmann, Gerd Häusler, Irene Slavc, Shivaram Avula, Ram Kumar, C. Mallucci, Benedetta Pettorini, D. Garlick, Barry Pizer, Gregory T. Armstrong, Toana Kawashima, Wendy M. Leisenring, Marilyn Stovall, Charles A. Sklar, L. L. Robison, M. Constantine Samaan, John K. Duckworth, Katrin Scheinemann, Noa Greenberg‐Kushnir, Sigal Freedman, Rina Eshel, N. Zverling, Ronit Elhasid, Rina Dvir, Michal Yalon, Abhaya V. Kulkarni, Shlomi Constantini, Sophie Wilne, J.-F. Liu, J. Trusler, S. Lundsell, C.O. Kennedy, Lynn Clough, N Dickson, Monica Lakhanpaul, M Baker, Jon S. Dudley, R. Grundy, D Walker, Katja von Hoff, Nadine Herzog, H. Ottensmeier, Desiree Grabow, N. U. Gerber, C. Friedrich, André O. von Bueren, Anika Resch, Rolf‐Dieter Kortmann, Peter Kaatsch, H. G. Doerr, Stefan Rutkowski, F. del Bufalo, A. Mastronuzzi, Annalisa Serra, Luigi De Sio, F. Locatelli, Veronica Biassoni, M.C. Leonardi, Daniela Ajovalasit, Daria Riva, Chiara Vago, Arianna Usilla, Paola Fidani, Annalisa Serra, Elisabetta Schiavello, F. Gariboldi, Maura Massimino, R Lober, Simon T. Perrault, S. Partap, Michael J. Edwards, P. Fisher, Kristen W. Yeom, Duarte Salgado, Sofía Nunes, Sofia Vinhais, Duarte Salgado, Sofía Nunes, Sofia Vinhais, Elizabeth Wells, Kristy Seidel, N. J. Ullrich, Wendy M. Leisenring, Gregory T. Armstrong, Lisa Diller, Allison A. King, Kevin R. Krull, Joseph P. Neglia, L. L. Robison, Marilyn Stovall, Kevin Whelan, Charles A. Sklar, Charles E. Russell, E. Bouffet, David Brownstone, C. Kaise, C.O. Kennedy, Kim Bull, David Culliford, Mathilde Chevignard, H. Spoudeas, G. Calaminus, D. Bertin, Stefano Vallero, E. Romano, M. E. Basso, Eleonora Biasin, Franca Fagioli, Kristen Ziara, Allison J. L’Hotta, A. Williams, R. Thede, Kaitlyn Moore, Alex James, Allison A. King, E Gabrielsson Bjorn, Pontus Franzén, Anja Haag, Agata Lax, Isaac Moreno, Katrin Scheinemann, Joyce Obeid, Brian W. Timmons, W. Iwata, Sarah Wagner, J.-S. Lai, Kerry Waddell, Sharon VanLeeuwen, M. Newmark, J. R. Noonan, Kate O’Connell, M. Urban, Susan Yount, Stewart Goldman, J. Piscione, Derval Igoe, T. Cunningham, M. Orfus, E. Bouffet, Donald Mabbott, Cori Liptak, Peter Manley, Christopher J. Recklitis, P. Zhang, Furqan Shaikh, Indra Narang, E. Bouffet, Kishiko Matsumoto, Kai Yamasaki, K Okada, Hiroshi Fujisaki, Yuko Osugi, Junichi Hara, Kim Phipps, Dianne Gumley, Thomas S. Jacques, Darren Hargrave, Dawn E. Saunders, Antony Michalski, Peter Manley, Christine Chordas, Susan Chi, Nathan Robison, Pratiti Bandopadhayay, K. Marcus, Michael A. Zimmerman, Liliana Goumnerova, Mark W. Kieran, Sarah R. Brand, T. Brinkman, Christine Chordas, Brian L. Delaney, T. Diver, C. Rey, Peter Manley, Cori Liptak, Jennifer R. Madden,

BACKGROUND: Glutathione S-transferase (GST) enzymes are involved in detoxifying chemotherapy agents and clearing reactive oxygen species formed by radiation. In this study, we explored the relationship between the host GSTP1-105 polymorphism (rs1695), tumor GSTpi protein expression, and clinical outcomes in pediatric medulloblastoma. We hypothesized that the GSTP1-105 G-allele and increased tumor GSTpi expression would be associated with lower progression-free survival and fewer adverse events. METHODS: ...

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