Espen Bjertness, B. Frode Hansen, Gry Berseth, Jon Ketil Grønnesby,
Tópico(s): Dental Health and Care Utilization
1993 - Elsevier BV | The Lancet
Olav Trygstad, K. L. Reichelt, Irene Foss, Paul D. Edminson, Gry Anette Sælid, Jon Bremer, Kjell Hole, Harald Ørbeck, J.H. Johansen, J. B. B⊘ler, Kirsten Titlestad, P. K. Opstad,
Peptidic neurones may be considered as multisignal intergrators and transducers. When formation or release of peptide outstrips genetically determined breakdown capacity, overflow of peptides to the body fluids and urine may be expected. In this paper, pathological urinary chromatographic patterns of peptides are shown for genetic, functional and mixed disorders. Part symptoms of the disorders may be induced with the biologically isolated and purified peptides as well as with chemically synthesized ...
Tópico(s): Chemical Synthesis and Analysis
1980 - Cambridge University Press | The British Journal of Psychiatry
Sonya Piskounova, Lars Gedda, Gry Hulsart‐Billström, Jöns Hilborn, Tim Bowden,
This study presents a thorough in vitro and in vivo characterization of the delivery of bone morphogenetic protein 2 (BMP-2) from a hyaluronan-based hydrogel system. The in vitro release of BMP-2 from similar hydrogels has previously been studied by enzyme-linked immunosorbent assay (ELISA), by which only a fraction of the loaded protein is detected. In the current study, 125I radiolabelling was used instead to monitor BMP-2 in vitro and in vivo. To minimize protein loss during handling, 125I-BMP- ...
Tópico(s): 3D Printing in Biomedical Research
2012 - Wiley | Journal of Tissue Engineering and Regenerative Medicine
Thomas E. Grys, Lynne M. Sloan, Jon E. Rosenblatt, Robin Patel,
ABSTRACT Shiga toxin (Stx)-producing Escherichia coli (STEC) bacteria are a frequent cause of food-borne gastroenteritis, hemorrhagic colitis, and hemolytic uremic syndrome. Because antimicrobial agents are generally contraindicated in patients infected with STEC, a sensitive and specific diagnostic test with rapid turnaround is essential. Current culture methods may fail to detect non-O157 STEC. We evaluated a Stx gene real-time PCR assay using hybridization probes and the LightCycler instrument ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
2009 - American Society for Microbiology | Journal of Clinical Microbiology
Gry Gundersen, Jon Aars, Harry P. Andreassen, Rolf A. Ims,
We used a field experiment with replicate populations of a particular geographic race of root voles (Microtus oeconomus) with different degrees of inbreeding to test whether inbreeding effects were expressed in demographic parameters. This geographic race had been shown to exhibit reduced reproductive rates in the laboratory resulting from inbreeding depression. There were no effects of inbreeding on population growth rate or any demographic parameter. Inbred animals grew less than outbred animals ...
Tópico(s): Wildlife Ecology and Conservation
2001 - NRC Research Press | Canadian Journal of Zoology
article Free AccessProgramming pearls Authors: Jon Bentley AT&T Bell Laboratories, Room 2C-317, 600 Mountain Avenue, Murray Hill, NJ AT&T Bell Laboratories, Room 2C-317, 600 Mountain Avenue, Murray Hill, NJView Profile , David Gries View Profile Authors Info & Claims Communications of the ACMVolume 30Issue 401 April 1987pp 284–290https://doi.org/10.1145/32232.315727Published: ...
Tópico(s): Evolutionary Algorithms and Applications
1987 - Association for Computing Machinery | Communications of the ACM
Ellen B. Roll, Jon E. Dahl, Gry Runningen, Else Morisbak,
Resin-based dental materials polymerized using blue light are frequently used in dental practice and may come in contact with the oral mucosa. Remnants from oral hygiene product ingredients, such as sodium lauryl sulfate (SLS), add to the chemical exposure of the mucosa. The aim of the present in vitro study was to elucidate the cytotoxic effects in terms of apoptosis and necrosis after exposures to combinations of an adhesive (0.5% and 0.6%), SLS (concentration range 0.0025%-0.0075%), and irradiation ...
Tópico(s): bioluminescence and chemiluminescence research
2004 - Wiley | European Journal Of Oral Sciences
Sonya Stenfelt, Gry Hulsart‐Billström, Lars Gedda, Kristoffer Bergman, Jöns Hilborn, Sune Larsson, Tim Bowden,
Tópico(s): dental development and anomalies
2014 - Springer Science+Business Media | Journal of Materials Science Materials in Medicine
Gry Stålsett, Tore Gude, Michael Helge Rønnestad, Jon T. Monsen,
Existential suffering may contribute to treatment-resistant depression. The "VITA" treatment model was designed for such patients with long-standing depression accompanied by existential and/or religious concerns. This naturalistic effectiveness study compared the VITA model (n = 50) with a "treatment as usual" comparison group (TAU; n = 50) of patients with treatment-resistant depression and cluster c comorbidity. The TAU patients were matched on several characteristics with the VITA patients. The VITA ...
Tópico(s): Mental Health Treatment and Access
2012 - Routledge | Psychotherapy Research
Gry Hulsart‐Billström, Kristoffer Bergman, Brittmarie Andersson, Jöns Hilborn, Sune Larsson, Kenneth B. Jonsson,
The development of biomaterial for bone regeneration requires animal models that are reliable and designed to mimic clinically relevant situations. We have previously investigated hydrogels comprised of modified hyaluronic acid and polyvinyl alcohol in models of ectopic bone formation. This hydrogel induces bone regeneration when loaded with bone morphogenetic proteins (BMPs). To allow further optimization of hydrogels, we developed a new, femoral, non-critical-sized cortical defect model. In the ...
Tópico(s): Spine and Intervertebral Disc Pathology
2012 - Wiley | Journal of Tissue Engineering and Regenerative Medicine
Eva Engelhardt, Stéphanie Houis, Thomas Gries, Jöns Hilborn, Myriam Adam, Florian Μ. Wurm,
Synthetic biomaterials play an important role in regenerative medicine. To be effective they must support cell attachment and proliferation in addition to being non-toxic and non-immunogenic. We used a suspension-adapted Chinese hamster ovary-derived cell line expressing green fluorescent protein (GFP) to assess cell attachment and growth on synthetic biomaterials by direct measurement of GFP-specific fluorescence. To simplify operations, all cell cultivation steps were performed in orbitally-shaken, ...
Tópico(s): Viral Infectious Diseases and Gene Expression in Insects
2009 - Springer Science+Business Media | Biotechnology Letters
Gry Hulsart‐Billström, Pik Kwan Yuen, Richard Marsell, Jöns Hilborn, Sune Larsson, Dmitri Ossipov,
Regeneration of bone by delivery of bone morphogenetic proteins (BMPs) from implantable scaffolds is a promising alternative to the existing autologous bone grafting procedures. Hydrogels are used extensively in biomaterials as delivery systems for different growth factors. However, a controlled release of the growth factors is necessary to induce bone formation, which can be accomplished by various chemical functionalities. Herein we demonstrate that functionalization of a hyaluronan (HA) hydrogel ...
Tópico(s): Connective tissue disorders research
2013 - American Chemical Society | Biomacromolecules
Hong Yan, Tommaso Casalini, Gry Hulsart‐Billström, Shujiang Wang, Oommen P. Oommen, Matteo Salvalaglio, Sune Larsson, Jöns Hilborn, Oommen P. Varghese,
Synthetic scaffolds that possess an intrinsic capability to protect and sequester sensitive growth factors is a primary requisite for developing successful tissue engineering strategies. Growth factors such as recombinant human bone morphogenetic protein-2 (rhBMP-2) is highly susceptible to premature degradation and to provide a meaningful clinical outcome require high doses that can cause serious side effects. We discovered a unique strategy to stabilize and sequester rhBMP-2 by enhancing its molecular ...
Tópico(s): Cellular Mechanics and Interactions
2018 - Elsevier BV | Biomaterials
Hege O. Ohnstad, Elin Borgen, Ragnhild Sørum Falk, Tonje G. Lien, Marit Aaserud, My Sveli, Jon Amund Kyte, Vessela N. Kristensen, Gry Aarum Geitvik, Ellen Schlichting, Erik A. Wist, Thérese Sørlie, Hege G. Russnes, Bjørn Naume,
The aim of this study was to investigate the prognostic value of the PAM50 intrinsic subtypes and risk of recurrence (ROR) score in patients with early breast cancer and long-term follow-up. A special focus was placed on hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) pN0 patients not treated with chemotherapy.Patients with early breast cancer (n = 653) enrolled in the observational Oslo1 study (1995-1998) were followed for distant recurrence and breast cancer death. ...
Tópico(s): HER2/EGFR in Cancer Research
2017 - BioMed Central | Breast Cancer Research
Gry Bang-Kittilsen, Jens Egeland, Tom Langerud Holmen, Therese Torgersen Bigseth, Eivind Andersen, Jon Mordal, Pål Ulleberg, John Abel Engh,
Tópico(s): Heart Rate Variability and Autonomic Control
2020 - Springer Science+Business Media | European Archives of Psychiatry and Clinical Neuroscience
Jon Rahbek-Clemmensen, Gry Thomasen,
The Ilulissat Meeting in 2008 was widely seen as the onset of enhanced cooperation between the five Arctic coastal states (Canada, Denmark (via Greenland), Norway, Russia, and the United States, commonly known as the A5). At the time, many diplomats and analysts feared that this enhanced emphasis of coastal state cooperation would undermine existing governance structures in the region, most importantly the Arctic Council. This article looks back at the period between 2008 and 2019 in order to examine ...
Tópico(s): Polar Research and Ecology
2020 - Elsevier BV | Marine Policy
Gry Hulsart‐Billström, Sonya Piskounova, Lars Gedda, Brittmarie Andersson, Kristoffer Bergman, Jöns Hilborn, Sune Larsson, Tim Bowden,
Tópico(s): Periodontal Regeneration and Treatments
2013 - Springer Science+Business Media | Journal of Materials Science Materials in Medicine
Gry Gundersen, Jon Aars, Harry P. Andreassen, Rolf A. Ims,
Tópico(s): Animal Ecology and Behavior Studies
2001 - NRC Research Press | Canadian Journal of Zoology
Gry Hulsart‐Billström, Qinghong Hu, Kristoffer Bergman, Kenneth B. Jonsson, Jonas Åberg, Ruikang Tang, Sune Larsson, Jöns Hilborn,
Current treatment of fractures often involves the use of bone graft or bone morphogenetic proteins (BMP) to induce fracture healing, especially in patients with a compromised healing capacity. BMP has to be delivered in conjunction with a carrier. Unfortunately, there are drawbacks and limitations with current carriers, including their bovine origin which carries the risk of an immunological response. The physical properties also limit the use to open surgical procedures, as it cannot be injected. ...
Tópico(s): Bone health and osteoporosis research
2011 - Elsevier BV | Acta Biomaterialia
Gry Bang-Kittilsen, John Abel Engh, René Holst, Tom Langerud Holmen, Therese Torgersen Bigseth, Eivind Andersen, Jon Mordal, Jens Egeland,
Introduction High-intensity interval training (HIIT) may improve cardiorespiratory fitness (CRF) and mental health. The current observer-blinded RCT investigates the sparsely studied efficiency of HIIT in reducing psychotic and non-psychotic symptoms in schizophrenia and complements previous studies by investigating whether symptom reduction following HIIT is associated with, putatively partly mediated by, increased VO 2 max. Methods Participants (outpatients meeting diagnostic criteria for schizophrenia) ...
Tópico(s): Cardiovascular and exercise physiology
2022 - Frontiers Media | Frontiers in Psychiatry
John Abel Engh, Jens Egeland, Ole A. Andreassen, Gry Bang-Kittilsen, Therese Torgersen Bigseth, Tom Langerud Holmen, Egil W. Martinsen, Jon Mordal, Eivind Andersen,
People with schizophrenia often have an unhealthy sedentary lifestyle with low level of physical activity and poor cardiorespiratory fitness - an important predictor of cardiovascular disease. We investigated the relations between cardiorespiratory fitness and both sedentary time and different aspects of physical activity, such as daily steps, light intensity physical activity, and moderate-to-vigorous physical activity. Using accelerometer as an objective measure of sedentary time and physical activity ...
Tópico(s): Sleep and related disorders
2019 - Frontiers Media | Frontiers in Psychiatry
Kristin Vanderbilt, Jon Ide, Corinna Gries, Susanne Grossman‐Clarke, Paul C. Hanson, Margaret O’Brien, Mark Servilla, C.A. Smith, Robert B. Waide, Kyle Zollo‐Venecek,
Abstract For many ecologists, publishing data in a data repository is a new, unfamiliar task. To reduce the learning curve, the Environmental Data Initiative has developed user‐friendly software to make capturing and submitting data and metadata a simple process. In this article, we introduce ezEML and discuss use cases for researchers who publish data infrequently or information managers who regularly update multiple datasets.
Tópico(s): Species Distribution and Climate Change
2022 - Ecological Society of America | Bulletin of the Ecological Society of America
Paula Rodríguez‐Otero, Mario Boccadoro, Roman Hájek, Tomoaki Fujisaki, Jae Hoon Lee, Joaquín Martínez‐López, Paulo Lúcio, Zsolt Nagy, Ganna Usenko, Anna Marina Liberati, Mihaela Lazaroiu, Dariusz Woszczyk, Hiroyuki Takamatsu, Joanna Romejko‐Jarosińska, Stefan Knop, Astrid Pavlovsky, Cecily Forsyth, Takayuki Ishikawa, Katharine S. Gries, Huiling Pei, Anupa Kudva, Jon Ukropec, Susan Wróblewski, Robin Carson, Meletios Α. Dimopoulos,
Introduction: DARA is a human IgGκ monoclonal antibody targeting CD38 with a direct on-tumor and immunomodulatory mechanism of action. In the phase 3 ALCYONE study (median follow-up of 40.1 months), DARA in combination with VMP (D-VMP) reduced the risk of disease progression or death by 58% versus VMP alone (median 36.4 vs 19.3 months; HR, 0.42; 95% CI, 0.34-0.51; P<0.0001) and demonstrated a significant overall survival (OS) benefit (median not reached in either group; HR, 0.60; 95% CI, 0.46- ...
Tópico(s): Cancer therapeutics and mechanisms
2020 - Elsevier BV | Blood
Jo Eidet, Gry Dahle, J. F. Bugge, Bjørn Bendz, Kjell Arne Rein, Lars Aaberge, Jon Offstad, Erik Fosse, Svend Aakhus, Per Steinar Halvorsen,
Left ventricular function is expected to improve after transcatheter aortic valve implantation due to the acute reduction in afterload, but does not occur in all patients. We hypothesized that the immediate intraoperative response in systolic left ventricular longitudinal motion during the procedure could be a predictor of short-term outcome. Sixty-four patients treated with transcatheter aortic valve implantation for severe aortic stenosis were included. Transoesophageal 4- and 2-chamber echocardiograms ...
Tópico(s): Infective Endocarditis Diagnosis and Management
2015 - Oxford University Press | Interactive Cardiovascular and Thoracic Surgery
Therese Torgersen Bigseth, John Abel Engh, Jens Egeland, Eivind Andersen, Ole A. Andreassen, Gry Bang-Kittilsen, Ragnhild Sørum Falk, Tom Langerud Holmen, Morten Lindberg, Jon Mordal, Jimmi Nielsen, Nils Eiel Steen, Thor Ueland, Torkel Vang, Mats Fredriksen,
Abstract Background There is evidence of increased low grade inflammation (LGI) in schizophrenia patients. However, the inter-individual variation is large and the association with demographic, somatic and psychiatric factors remains unclear. Our aim was to explore whether levels of the novel LGI marker soluble urokinase plasminogen activator receptor (suPAR) were associated with clinical factors in schizophrenia and if such associations were sex-dependent. Method In this observational study a total ...
Tópico(s): Inflammasome and immune disorders
2021 - BioMed Central | BMC Psychiatry
... books and articles on Koguryo by the time Gries was writing his article. Compared with South Korea, it is certainly true that most Chinese did not pay much attention to Koguryo; that is because to most Chinese Koguryo is not a significant issue. 20. Jon Herskovitz, ‘South Korea uses TV dramas in history ...
Tópico(s): China's Ethnic Minorities and Relations
2012 - Routledge | Journal of Contemporary China
Kevin S. Black, Jon R. Sloan, Thomas Gries,
Source control i.e. the reduction of contamination from upstream or diffuse sources, is a critical element in any management plan for contaminated waterways. If source control measures are not successfully implemented, then a situation exists in which contamination will continue through time, and the cleanup of waterway segments becomes increasingly problematic. To provide greater understanding of the issues surrounding source control, it is essential to have some knowledge of contaminant sources ...
Tópico(s): Hydrology and Sediment Transport Processes
2013 - EDP Sciences | EPJ Web of Conferences
Therese Torgersen Bigseth, Mats Fredriksen, Jens Egeland, Eivind Andersen, Ole A. Andreassen, Gry Bang-Kittilsen, Ragnhild Sørum Falk, Tom Langerud Holmen, Egil W. Martinsen, Jon Mordal, Jimmi Nielsen, Nils Eiel Steen, Thor Ueland, Torkel Vang, John Abel Engh,
Tópico(s): Stress Responses and Cortisol
2021 - Elsevier BV | Schizophrenia Research
Jo Eidet, Gry Dahle, J. F. Bugge, Bjørn Bendz, Kjell Arne Rein, Lars Aaberge, Jon Offstad, Erik Fosse, Svend Aakhus, Per Steinar Halvorsen,
Transcatheter aortic valve implantation improves survival in patients with severe aortic stenosis who are ineligible for surgical valve replacement; however, not all patients benefit from the procedure. We endeavoured to identify these patients using intraoperative echocardiography and hypothesized that intraoperative left ventricular function in response to the acute afterload reduction during the procedure was related to long-term outcomes. We prospectively included 64 patients who were scheduled ...
Tópico(s): Aortic Disease and Treatment Approaches
2016 - Oxford University Press | Interactive Cardiovascular and Thoracic Surgery
Chavdar Botev, Hubert Chao, Theodore Chao, Yim Cheng, Raymond Doyle, Sergey Grankin, Jon Guarino, Saikat Guha, Pei-Chen Lee, Dan Perry, Christopher Ré, Ilya Rifkin, Tingyan Yuan, Dora Abdullah, Kathy Carpenter, David Gries, Dexter Kozen, Andrew C. Myers, David Schwartz, Jayavel Shanmugasundaram,
CMS is a secure and scalable web-based course management system developed by the Cornell University Computer Science Department. The system was designed to simplify, streamline, and automate many aspects of the workflow associated with running a large course, such as course creation, importing students, management of student workgroups, online submission of assignments, assignment of graders, grading, handling regrade requests, and preparation of final grades. In contrast, other course management ...
Tópico(s): Educational Technology and Assessment
2005 - Association for Computing Machinery | ACM SIGCSE Bulletin