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Luís E.C. Conceição, Cláudia Aragão, Jorge Dias, Benjamín Costas, Genciana Terova, Catarina I.M. Martins, Lluís Tort,

Tópico(s): Reproductive biology and impacts on aquatic species

2012 - Springer Science+Business Media | Fish Physiology and Biochemistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Wellington S. Mendes, Nelson J. L. ARAGÃO, Henrique Jorge dos Santos, Lourdes RAPOSO, Pedro F.C. Vasconcelos, Elizabeth Salbé Travassos da Rosa, Mauro R. Elkhoury,

The authors report a confirmed case of hantavirus pulmonary syndrome in the rural area of the municipality of Anajatuba, state of Maranhão. Two other suspected cases from the same region are also described. The confirmed case involved a previously healthy young woman who died with signs and symptoms of acute respiratory insufficiency 5 days after presenting fever, myalgia and a dry cough. The patient was a student who was helping her parents with work in the fields; it was a habit of the family ...

Tópico(s): Mosquito-borne diseases and control

2001 - UNIVERSIDADE DE SÃO PAULO | Revista do Instituto de Medicina Tropical de São Paulo

Artigo Brasil Produção Nacional Revisado por pares

Nylane Maria Nunes de Alencar, Flávio da Silveira Bitencourt, Ingrid Samantha Tavares de Figueirêdo, Patrícia Bastos Luz, Roberto César Pereira Lima‐Júnior, Karoline S. Aragão, Pedro Jorge Caldas Magalhães, Gerly Anne de Castro Brito, Ronaldo A. Ribeiro, Ana Paula Fragoso de Freitas, Márcio V. Ramos,

Intestinal mucositis (IM) is the critical side effect of irinotecan (CPT-11), which is the front-line drug used for the treatment of colorectal cancer. This study aimed to evaluate the effectiveness of latex proteins (LP) from Calotropis procera to prevent IM and diarrhea in animals. Swiss mice were treated daily with saline or LP (1, 5, or 50 mg/kg, i.v.) 24 h prior to CTP-11 (75 mg/kg/4 days, i.p) and for additional 6 days. Animal survival, body weight variation, and diarrhea were registered. After ...

Tópico(s): Phytochemistry and Bioactive Compounds

2016 - Wiley | Phytotherapy Research

Artigo Brasil Produção Nacional Revisado por pares

Lidiane Costa de Souza, Nara Sousa Rodrigues, D A Cunha, Victor Pinheiro Feitosa, Sérgio Lima Santiago, Alessandra Reis, Alessandro Dourado Loguércio, Thalita de Paris Matos, Vicente de Paulo Aragão Sabóia, Jorge Perdigão,

To compare the clinical behavior of Proanthocyanidins (PA)-free and PA-containing two-step etch-and-rinse adhesive used underneath resin composite restorations in non-carious cervical lesions (NCCLs) over a 6- (6 M) and 24-month (24 M) period.135 restorations were randomly placed in 45 subjects. The NCCLs were conditioned (37% phosphoric acid for 15 s) and distributed into 3 groups: Control (EX0) - ExciTE F (Ivoclar Vivadent) adhesive applied following the manufacturer's recommendations; EX2 and EX5 - 2 wt% ...

Tópico(s): Dental Research and COVID-19

2018 - Elsevier BV | Journal of Dentistry

Artigo Acesso aberto

Jaqueline Moura Silva, Adriana Melo Moura, Guilherme José Aragão Barbosa, Jorge Luiz de Souza Mota, Rafaela Sampaio Cunha, Rucenita Leite Queiroz, Thais Figueiredo Santos, Diógenes José Gusmão Coutinho,

ABCTRACTThis research aims to analyze the concept of emotional intelligence, its impact on people's lives and how it is possible to develop this ability.A bibliographic search was made, where books and articles on the subject were analyzed, emphasizing the authors who are reference in the subject such as Weisinger, Mayer, Salovey and Goleman.In today's world, it is not enough just to have technical knowledge on a particular subject, it is not enough to be an expert in an area, it is also necessary ...

Tópico(s): Emotional Intelligence and Performance

2020 - Brazilian Journal of Development | Brazilian Journal of Development

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Paula Fabiana Saldanha Tschinkel, Elaine S. P. Melo, Hugo Santos Pereira, Kassia R. N. Silva, Daniela Granja Arakaki, Nayara Vieira de Lima, Melina Ribeiro Fernandes, Luana Carolina Santos Leite, Eliane S. P. Melo, Petr Melnikov, Paulo R. Espindola, Igor Domingos de Souza, Valdir Aragão do Nascimento, Jorge Luiz Raposo, Ana C. R. Geronimo, Francisco José Mendes dos Reis, Valter Aragão do Nascimento,

The determination of Cd, Co, Cr, Cu, Fe, Na, Zn, and Pb by inductively coupled plasma-optical emission spectrometry (ICP OES) was performed on dry matter and decoctions of the medicinal plants Cordia salicifolia , Chiococca alba (L.) Hitchc., and Echites peltata used as an appetite suppressant and diuretic in Brazil. The accuracy of the measurements was analyzed by the spike recovery test. Results showed that the concentration of these seven metals (Cd, Co, Cr, Cu, Fe, Na, and Zn) in dry plant samples ...

Tópico(s): Heavy Metal Exposure and Toxicity

2020 - Hindawi Publishing Corporation | BioMed Research International

Artigo Acesso aberto Revisado por pares

Verena Krähling, Stephanie Erbar, Alexandra Kupke, Sara S. Nogueira, Kerstin C. Walzer, Hendrik Berger, Erik Dietzel, Sandro Halwe, Cornelius Rohde, Lucie Sauerhering, Letícia Aragão-Santiago, Jorge Moreno Herrero, Sonja Witzel, Heinrich Haas, Stephan Becker, Uǧur Şahin,

Emerging and re-emerging viruses, such as Zaire Ebola virus (EBOV), pose a global threat and require immediate countermeasures, including the rapid development of effective vaccines that are easy to manufacture. Synthetic self-amplifying RNAs (saRNAs) attend to these needs, being safe and strong immune stimulators that can be inexpensively produced in large quantities, using cell-free systems and good manufacturing practice. Here, the first goal was to develop and optimize an anti-EBOV saRNA-based ...

Tópico(s): SARS-CoV-2 and COVID-19 Research

2022 - Elsevier BV | Molecular Therapy

Artigo Acesso aberto Brasil Produção Nacional

Nielson S. Trindade, Artur Henrique Kronbauer, Helder G. Aragão, Jorge Campos,

The combination of data from sensors embedded in vehicles and smartphones promises to generate great innovations in intelligent transportation systems. This article presents Driver Rating, a mobile application to evaluate the behavior of drivers based on the data gathered from vehicles´ and smartphones´ sensors. The Driver Rating application analyzes five variables (fuel consumption, carbon dioxide emission, speed, longitudinal acceleration, and transverse acceleration) to evaluate driver´s behaviors ...

Tópico(s): Traffic Prediction and Management Techniques

2021 - | South Florida Journal of Development

Artigo Acesso aberto Revisado por pares

Cláudia Aragão, Luís E.C. Conceição, Jorge Dias, Ana C. Marques, Emídio F. Gomes, María Teresa Dinis,

The objective of this work was to evaluate the effect of a dietary amino acid imbalance, originating from the use of a soy protein concentrate (SPC) as the major protein source, on the growth performance and amino acid metabolism of Senegalese sole (Solea senegalensis) postlarvae. Senegalese sole (85.6±24.6 mg wet weight) were fed one of two experimental diets: one based on fish meal (FM) and another based on SPC. Diets were isonitrogenous (around 56% crude protein) and isoenergetic. Diet acceptability ...

Tópico(s): Reproductive biology and impacts on aquatic species

2003 - Wiley | Aquaculture Research

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Luan Pereira Diniz, Isadora Matias, Ana Paula Bérgamo Araújo, Matheus Nunes Garcia, Fernanda G. Q. Barros‐Aragão, Soniza Vieira Alves‐Leon, Jorge Marcondes de Souza, Débora Foguel, Cláudia P. Figueiredo, Carolina Braga, Luciana Romão, Flávia Carvalho Alcântara Gomes,

Abstract Parkinson's disease (PD) is characterized by selective death of dopaminergic neurons in the substantia nigra, degeneration of the nigrostriatal pathway, increases in glutamatergic synapses in the striatum and aggregation of α‐synuclein. Evidence suggests that oligomeric species of α‐synuclein (αSO) are the genuine neurotoxins of PD. Although several studies have supported the direct neurotoxic effects of αSO on neurons, their effects on astrocytes have not been directly addressed. Astrocytes ...

Tópico(s): Nerve injury and regeneration

2019 - Wiley | Journal of Neurochemistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Tatiana Aragão Figueiredo, Renato Gonçalves Fialho Neto, Jorge Lima de Magalhães,

Abstract The paper aims to contribute as a reflection on the public production of medicines in Brazil. Public producers present themselves as strategic in Brazil, either as price regulators, in meeting the demands of the Ministry of Health (MoH) on neglected products and those at risk of shortage to SUS. The study used the official bases of the MoH, National Health Surveillance Agency (ANVISA) and Website of Official Pharmaceutical Laboratories (OPL). Thirty-three OPL were identified, 16 with active ...

Tópico(s): Health Systems, Economic Evaluations, Quality of Life

2021 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva

Artigo Brasil Produção Nacional Revisado por pares

Francisco Pablo Huáscar Aragão Pinheiro, Amélia P. A. Travassos da Rosa, Jorge Fernando Soares Travassos da Rosa, Ricardo Ishak, Ronaldo Barros de Freitas, Maria L. C. Gomes, James W. LeDuc, Otávio Oliva,

Between 1961 and 1978 seven outbreaks of Oropouche (ORO) virus have been documented in Pará State, Brazil. The clinical picture of ORO infection is characterized by fever, chills, headache, muscle pain, arthralgia, and other minor clinical manifestations. No deaths have to date been attributed to the disease but a proportion of patients become severely ill, occasionally to the point of prostration. Recurrence of symptoms has been observed in some patients, especially within the first 10 days after ...

Tópico(s): Vector-Borne Animal Diseases

1981 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene

Artigo Brasil Produção Nacional Revisado por pares

Hugo Santos Pereira, Kássia Roberta Nogueira da Silva, Elaine Silva de Pádua Melo, Valter Aragão do Nascimento, Jorge Luiz Raposo,

A promising multi-energy calibration procedure for the determination of Ca, Cu, Fe, K, Mg, Mn, Ni, and Zn by ICP OES was evaluated.

Tópico(s): Heavy metals in environment

2020 - Royal Society of Chemistry | Journal of Analytical Atomic Spectrometry

Artigo Acesso aberto Revisado por pares

Rita Teodósio, Cláudia Aragão, Rita Colen, Raquel Carrilho, Jorge Dias, Sofía Engrola,

Gilthead seabream (Sparus aurata) is vulnerable to low water temperature, which may occur in the Southern Europe and Mediterranean region during Winter. Fish are poikilothermic animals, so feed intake, digestion, metabolism and ultimately growth are affected by water temperature. This study aimed to evaluate growth performance, feed utilisation, nutrient apparent digestibility, and N losses to the environment in seabream juveniles reared under low temperature (13 degrees Celsius). Three isolipid and ...

Tópico(s): Marine Bivalve and Aquaculture Studies

2021 - Elsevier BV | Aquaculture

Artigo Revisado por pares

R.M. Pereira, Patrícia Mesquita, Marcus Vinícius de Aragão Batista, M.C. Baptista, J.P. Barbas, Jorge Pimenta, Isabel Cristina França dos Santos, M.R. Marques, M.I. Vasques, R.M. Pereira, F. Santos-Silva, M. C. Oliveira Sousa, C.M.G.A. Fontes, A.E.M. Horta, José A. M. Prates, C.C. Marques,

Transgenic knockout of the gene encoding the prion-like protein Doppel leads to male infertility in mice. The precise role of Doppel in male fertility is still unclear, but sperm from Doppel-deficient mice appear to be unable to undergo the normal acrosome reaction necessary to penetrate the zona pellucida of the oocyte. The objective of this study was to characterize Doppel (Prnd) gene polymorphisms in eight Portuguese sheep breeds and to determine a possible relationship between these polymorphisms ...

Tópico(s): Animal Genetics and Reproduction

2008 - Elsevier BV | Animal Reproduction Science

Artigo Acesso aberto Revisado por pares

Cláudia Aragão, Miguel Cabano, Rita Colen, Juan Fuentes, Jorge Dias,

To support the expected increase in aquaculture production during the next years, a wider range of alternative ingredients to fishmeal is needed, towards contributing to an increase in production sustainability. This study aimed to test diets formulated with non-conventional feed ingredients on gilthead seabream (Sparus aurata) growth performance, feed utilization, apparent digestibility of nutrients and nutrient outputs to the environment. Four isonitrogenous and isoenergetic diets were formulated: ...

Tópico(s): Marine Bivalve and Aquaculture Studies

2019 - Wiley | Aquaculture Nutrition

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

João Aragão e Pina, Ana Passos, M. Travis Maynard, Jorge Sinval,

Within the football and futsal refereeing context, even though referees work within teams, there is very little research considering the implications of team dynamics. In response, this study starts to address this gap in the literature by investigating the moderating effect of mental models on the relationship between self-efficacy beliefs and perceptions of team adaptation within the exciting context of professional and national football and futsal refereeing. We obtained online questionnaires ...

Tópico(s): Sports Analytics and Performance

2020 - Elsevier BV | Psychology of sport and exercise

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Bruno Cavalcante Mota, Bruno Albuquerque Neto, Suelly Helena de Araújo Barroso, Francisco Thiago Sacramento Aragão, Adelino Ferreira, Jorge Barbosa Soares, Lélio Antônio Teixeira Brito,

The recent increase in demand for electric energy and different ways of harvesting and generating it has been a key research stream in transportation infrastructure in Brazil. Since pavement structures are subjected to the mechanical load of millions of vehicles, the application of piezoelectric sensors is adequate, transforming deformations and vibrations on its layers into electric power. The general objective of this study was to investigate the use of piezoelectricity as a source of renewable ...

Tópico(s): Smart Materials for Construction

2022 - Multidisciplinary Digital Publishing Institute | Sustainability

Artigo Revisado por pares

Patrícia Mesquita, Marcus Vinícius de Aragão Batista, M.R. Marques, Isabel Cristina França dos Santos, Jorge Pimenta, R.M. Pereira, Inês Carolino, F. Santos-Silva, M. C. Oliveira Sousa, L.T. Gama, C.M.G.A. Fontes, A.E.M. Horta, José A. M. Prates, R.M. Pereira,

The establishment of an association between prion protein gene (PRNP) polymorphisms and scrapie susceptibility in sheep has enabled the development of breeding programmes to increase scrapie resistance in the European Union. Intense selection for PRNP genotype may lead to correlated selection for genes linked to PRNP. We intended to investigate if any association exists between genetic variation in prion-like protein Doppel gene (PRND) and scrapie susceptibility, determined through PRNP genotyping. ...

Tópico(s): Trace Elements in Health

2009 - Wiley | Animal Genetics

Artigo Revisado por pares

Benjamín Costas, Cláudia Aragão, José L. Soengas, Jesús M. Míguez, Paulo Rema, Jorge Dias, António Afonso, Luís E.C. Conceição,

The present study aimed to assess the effects of increased availability of dietary amino acids (AA) on brain monoamine neurotransmitters and the metabolic processes resulting from stressful situations in fish. Senegalese sole (Solea senegalensis) juveniles (24.2 ± 0.4 g wet mass) were weekly subjected to an acute handling stressor (HDLG) or remained undisturbed (CTL). Additionally, both treatments were fed a control or a high protein (HP) diet (CTL, CTL HP, HDLG and HDLG HP). The HP diet slightly increased ...

Tópico(s): Physiological and biochemical adaptations

2011 - Elsevier BV | Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology

Artigo Brasil Produção Nacional Revisado por pares

Lidiane Costa de Souza, Nara Sousa Rodrigues, D A Cunha, Victor Pinheiro Feitosa, Sérgio Lima Santiago, Alessandra Reis, Alessandro Dourado Loguércio, Jorge Perdigão, Vicente de Paulo Aragão Sabóia,

This double-blind randomized clinical trial evaluated the influence of pre-treatment with proanthocyanidins (PA) from grape seed extract on the clinical behavior of a simplified etch-and-rinse adhesive placed in non-carious cervical lesions (NCCLs) over 6- and 24-months.A total of 135 restorations were randomly inserted in 45 subjects. The NCCLs were etched with 37 % phosphoric acid for 15 s and distributed into 3 groups: Control (PA0) - adhesive ExciTE F applied as per the manufacturer's recommendations; ...

Tópico(s): Orthodontics and Dentofacial Orthopedics

2020 - Elsevier BV | Journal of Dentistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Jéssica de Aragão Freire Ferreira Finger, Emília Maria França Lima, Kristy Soraya Coelho, Jorge Herman Behrens, Mariza Landgraf, Bernadette Dora Gombossy de Melo Franco, Uelinton Manoel Pinto,

Several actions in the realm of public policies and programs have been implemented worldwide to prevent and control the spread of COVID-19. As Brazil and many parts of the world are marked by regional, cultural, and social inequalities, risk communication and assimilation of protection recommendations by the public may be erratic, hampering the proper measurement of their effectiveness.Even though transmission of SARS-CoV-2 by foods is unlikely, this work aimed to evaluate the population's adherence ...

Tópico(s): COVID-19 Pandemic Impacts

2021 - Elsevier BV | Trends in Food Science & Technology

Revisão Revisado por pares

Luís E.C. Conceição, Cláudia Aragão, Nadège Richard, Sofía Engrola, Paulo J. Gavaia, Sara Mira, Jorge Dias,

Tópico(s): Physiological and biochemical adaptations

2009 - Springer Science+Business Media | Fish Physiology and Biochemistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Jamary Oliveira‐Filho, Leila C. Viana, Rodrigo M. Vieira-de-Melo, Frederico Faiçal, Jorge Andion Torreão, Flávio Augusto Guerreiro Aragão de Villar, Francisco José Farias Borges dos Reis,

Background and Purpose— Chagas disease (CD) is frequently associated with cardioembolic stroke in South America. Our objective was to identify the predictors of stroke in a region where CD is endemic. Methods— We screened 305 consecutive cardiopathy patients. Significant predictors of stroke in univariable analyses were included in a multivariable model. Results— Stroke was more frequent in CD (15.0%) compared with other cardiopathies (6.3%; P =0.015). Other predictors of stroke in univariable analyses ...

Tópico(s): Lysosomal Storage Disorders Research

2005 - Lippincott Williams & Wilkins | Stroke

Artigo Acesso aberto Revisado por pares

Manuel Sardinha, Sofía Engrola, P Gray,

... in Frontiers Manuel Sardinha Luís Conceição Sofia Engrola Jorge Dias Claudia Aragão Maria Teresa Dinis Paulo Gray Google Manuel Sardinha Luís Conceição Sofia Engrola Jorge Dias Claudia Aragão Maria Teresa Dinis Paulo Gray Google Scholar Manuel Sardinha Luís Conceição Sofia Engrola Jorge Dias Claudia Aragão Maria Teresa Dinis Paulo Gray PubMed Manuel Sardinha Luís Conceição Sofia Engrola Jorge Dias Claudia Aragão Maria Teresa Dinis Paulo Gray Related Article in ...

Tópico(s): Aquaculture disease management and microbiota

2014 - Frontiers Media | Frontiers in Marine Science

Artigo Acesso aberto Revisado por pares

Sofía Morais, Cláudia Aragão, Elsa Cabrita, Luís E.C. Conceição, María Constenla, Benjamín Costas, Jorge Dias, Neil Duncan, Sofía Engrola, Alicia Estévez, Enric Gisbert, Evaristo L. Mañanós, Luísa M.P. Valente, Manuel Yúfera, María Teresa Dinis,

Abstract Senegalese sole was one of the earliest identified candidate species with high potential for aquaculture diversification in the south of Europe. Its culture has been possible, and commercially attempted, for several decades, but intensive production has been slow to take off. This has been explained mostly by serious disease problems, high mortality at weaning, variable growth and poor juvenile quality. However, a strong and sustained research investment that started in the eighties has ...

Tópico(s): Aquatic life and conservation

2014 - Wiley | Reviews in Aquaculture

Artigo Revisado por pares

Cláudia Aragão, Rita Colen, Sara Ferreira, Wilson Pinto, Luís E.C. Conceição, Jorge Dias,

Abstract Senegalese sole farming is gaining “momentum” and the development of an optimised diet is pivotal to ensure its competitive and sustainable commercial culture. The lower fish performance often observed when replacing large amounts of dietary fishmeal by plant protein sources may result from an unbalanced supply of selected nutrients, such as taurine, which is absent in plants but abundant in fish. However, taurine is highly soluble in water and sole has a passive feeding behaviour. Therefore, ...

Tópico(s): Aldose Reductase and Taurine

2014 - Elsevier BV | Aquaculture