... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Produção Nacional
Tópico(s): Psychoanalysis and Psychopathology Research
2011 - | Tempo Psicanalítico
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Conceição Pereira, José L. Loureiro, Jorge Pinto‐Basto, Eva Brandão, Ana M. Lopes, Georgina Neves, Pureza Dias, Ruth Geraldes, Isabel Pavão Martins, Vítor Tedim Cruz, Erik‐Jan Kamsteeg, Han G. Brunner, Paula Coutinho, Jorge Sequeiros, Isabel Alonso,
PurposeHereditary spastic paraplegias compose a group of neurodegenerative disorders with a large clinical and genetic heterogeneity. Among the autosomal recessive forms, spastic paraplegia type 11 is the most common.MethodsTo better understand the spastic paraplegia type 11 mutation spectrum, we studied a group of 54 patients with hereditary spastic paraplegia. Mutation screening was performed by PCR amplification of SPG11 coding regions and intron boundaries, followed by sequencing. For the detection ...
Tópico(s): Genomics and Rare Diseases
2012 - Elsevier BV | Genetics in Medicine
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Produção Nacional
Isabel Silveira, Carlos J. Miranda, Laura Guimarães, M.-C. Moreira, Isabel Alonso, Pedro Mendonça, Anabela Ferro, Jorge Pinto‐Basto, João Coelho, Fátima Ferreirinha, John T. Poirier, E. Parreira, José Vale, Cristina Januário, Clara Barbot, Assunção Tuna, José Barros, Reiji Koide, Shoji Tsuji, Susan E. Holmes, Russell L. Margolis, Laura Bannach Jardim, Massimo Pandolfo, Paula Coutinho, Jorge Sequeiros,
Ten neurodegenerative disorders characterized by spinocerebellar ataxia (SCA) are known to be caused by trinucleotide repeat (TNR) expansions. However, in some instances the molecular diagnosis is considered indeterminate because of the overlap between normal and affected allele ranges. In addition, the mechanism that generates expanded alleles is not completely understood.To examine the clinical and molecular characteristics of a large group of Portuguese and Brazilian families with ataxia to improve ...
Tópico(s): DNA Repair Mechanisms
2002 - American Medical Association | Archives of Neurology
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Produção Nacional
Revisado por pares
Yoelvis Orozco‐Gonzalez, Kaline Coutinho, Jörge Peón, Sylvio Canuto,
The photophysics of the 1-nitronaphthalene molecular system, after the absorption transition to the first singlet excited state, is theoretically studied for investigating the ultrafast multiplicity change to the triplet manifold. The consecutive transient absorption spectra experimentally observed in this molecular system are also studied. To identify the electronic states involved in the nonradiative decay, the minimum energy path of the first singlet excited state is obtained using the complete ...
Tópico(s): Spectroscopy and Quantum Chemical Studies
2012 - American Institute of Physics | The Journal of Chemical Physics
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Kashish Goel, Randal J. Thomas, Ray W. Squires, Thais Coutinho, Jorge F. Trejo-Gutiérrez, Virend K. Somers, John J. Miles, Francisco López-Jiménez,
High cardiorespiratory fitness and body mass index (BMI) are associated with decreased mortality in patients with coronary artery disease. Our objective was to determine the joint impact of fitness and adiposity measures on all-cause mortality in this subgroup.Coronary artery disease patients (n = 855) enrolled in the Mayo Clinic cardiac rehabilitation program from 1993 to 2007 were included. Fitness levels were determined by cardiopulmonary exercise testing. Patients were divided into low and high ...
Tópico(s): Cardiac Health and Mental Health
2011 - Elsevier BV | American Heart Journal
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Produção Nacional
Revisado por pares
Cassamo U. Mussagy, Daniela Remonatto, Ariela Veloso de Paula, Rondinelli Donizetti Herculano, Valéria C. Santos‐Ebinuma, João A. P. Coutinho, Jorge F. B. Pereira,
Selective recovery and purification of carotenoids and lipids from oleaginous red yeast Rhodotorula glutinis require a complex integration of different downstream operations. Envisioning a future industrial application in the bioeconomy framework, an experimental planning was used to design ternary mixtures of bio-based solvents (biosolvents) for simultaneous recovery and selective separation of carotenoids (i.e., β-carotene and torularhodin) and fatty acids (i.e., margaric acid, stearic acid and pentadecylic ...
Tópico(s): Bioeconomy and Sustainability Development
2021 - Elsevier BV | Separation and Purification Technology
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Produção Nacional
Revisado por pares
Cassamo U. Mussagy, Valéria C. Santos‐Ebinuma, Rondinelli Donizetti Herculano, João A. P. Coutinho, Jorge F. B. Pereira, Adalberto Pessoa,
Cholinium-based eutectic solvents as a promising and sustainable solution for the extraction of carotenoids from microbial biomass and the preparation of biodegradable active biofilms.
Tópico(s): Ionic liquids properties and applications
2021 - Royal Society of Chemistry | Green Chemistry
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Produção Nacional
Revisado por pares
Cassamo U. Mussagy, Valéria C. Santos‐Ebinuma, Kiki Adi Kurnia, Ana Cláudia Dias, Pedro J. Carvalho, João A. P. Coutinho, Jorge F. B. Pereira,
Mixed biosolvents as a promising and environmentally benign solution for the recovery of carotenoids and lipids from yeast biomass.
Tópico(s): Enzyme Catalysis and Immobilization
2020 - Royal Society of Chemistry | Green Chemistry
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Marcelo M.R. de Melo, Maria Sapatinha, Joaquina Pinheiro, Marco F.L. Lemos, Narcisa M. Bandarra, Irineu Batista, Maria C. Paulo, Joana Coutinho, Jorge A. Saraiva, Inês Portugal, Carlos M. Silva,
The microalgae Aurantiochytrium sp. is a strong alternative source of ω-3 fatty acids, including docosahexaenoic acid (DHA). This work encompasses the optimization of SFE conditions to maximize the total extraction yield ηTotal, DHA content (CDHA), total phenolics content (TPC), and antioxidant capacity (AOC) of the extracts produced from Aurantiochytrium sp. biomass. A full factorial experimental plan was performed, comprising three factors (pressure, temperature, and flow rate) and two levels (200−300 ...
Tópico(s): Catalysis and Oxidation Reactions
2020 - Elsevier BV | Journal of CO2 Utilization
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Produção Nacional
Revisado por pares
Cassamo U. Mussagy, Valéria C. Santos‐Ebinuma, María González‐Miquel, João A. P. Coutinho, Jorge F. B. Pereira,
Rhodotorula glutinis (R. glutinis) yeasts are natural sources of intracellular carotenoids such as β-carotene, torularhodin, and torulene. Since these yeasts are constituted by a rigid cell-wall structure, the use of energy-saving and high-efficiency cell disruption procedures is critical for carotenoids recovery. A new technology using protic ionic liquids (PILs) was here evaluated as an alternative platform to permeabilize the R. glutinis cells and to improve the extraction of β-carotene, torularhodin, ...
Tópico(s): Electrochemical sensors and biosensors
2019 - American Chemical Society | ACS Sustainable Chemistry & Engineering
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Ana Cristina Tavares, João Loureiro, Sílvia Castro, António Pereira Coutinho, Jorge Paiva, Carlos Cavaleiro, Lı́gia Salgueiro, Jorge Canhoto,
Abstract For a clearer distinction between the four subspecies of Daucus carota native from Portugal (subsp. carota , subsp. maximus , subsp. gummifer and subsp. halophilus ), morphological features of the fruits, DNA content analyses by flow cytometry, and chemical characterization of the essential oils were undertaken. We found chemotaxonomic evidences to consider D. carota subsp. maximus as a separate species rather than a subspecies of D . carota . This separation is based on the morphometric analysis of ...
Tópico(s): Phytochemical compounds biological activities
2014 - Elsevier BV | Biochemical Systematics and Ecology
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Produção Nacional
Revisado por pares
Régis Kreitchmann, SX Li, VH Melo, Débora Fernandes Coelho, D. Heather Watts, Esaú João, Conrado Milani Coutinho, Jorge Alarcón, Siberry Gk,
Objective To examine maternal characteristics associated with adverse pregnancy outcomes among women infected with HIV . Design Prospective cohort study. Setting Multiple sites in L atin A merica and the C aribbean. Population Women infected with HIV enrolled in the P erinatal (2002–2007) and the L ongitudinal S tudy in L atin A merican C ountries ( LILAC ; 2008–2012) studies of the E unice K ennedy S hriver N ational I nstitute of C hild H ealth and H uman D evelopment ( NICHD ) I nternational S ite D evelopment ...
Tópico(s): Pregnancy and preeclampsia studies
2014 - Wiley | BJOG An International Journal of Obstetrics & Gynaecology
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Produção Nacional
Revisado por pares
Eliana Marisa Ramos, Sandra Martins, Isabel Alonso, Vanessa E Emmel, Maria Luiza Saraiva Pereira, Laura Bannach Jardim, Paula Coutinho, Jorge Sequeiros, Isabel Silveira,
Abstract The spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant neurodegenerative disease characterized by gait and limb ataxia. This disease is caused by the expansion of a (CAG) n located in the ATXN2 , that encodes a polyglutamine tract of more than 34 repeats. Lately, alleles with 32–33 CAGs have been associated to late‐onset disease cases. Repeat interruptions by CAA triplets are common in normal alleles, while expanded alleles usually contain a pure repeat tract. To investigate the ...
Tópico(s): Muscle Physiology and Disorders
2009 - Wiley | American Journal of Medical Genetics Part B Neuropsychiatric Genetics
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
José L. Loureiro, Leonor Miller‐Fleming, Carolina Thieleke‐Matos, Paula Magalhães, Vítor Tedim Cruz, Paula Coutinho, Jorge Sequeiros, Isabel Silveira,
Objectives – The hereditary spastic paraplegias (HSP) are a genetically and clinically heterogeneous group of neurodegenerative disorders, mainly characterized by a progressive spasticity and weakness of the lower limbs. Mutations in the SPG4 and SPG3A genes are responsible for approximately 50% of autosomal dominant HSP. To genetically diagnose the Portuguese families with HSP, mutation analysis was performed for the SPG4 and SPG3A genes. Patients and methods – Analysis was performed by polymerase chain ...
Tópico(s): Genetic Neurodegenerative Diseases
2008 - Wiley | Acta Neurologica Scandinavica
... 1644. f. 35. 9. (a) Francisco do Souza Coutinho [Portuguese minister in Holland] to the King, with ... Extract from a reply to the accusations of Jorge de Sampaio, ]Procurator of the Maranhão, against the ...
1729 - Gale Group | SASII
Produção Nacional
Revisado por pares
S. C. Coutinho, Jorge Vitório Pereira,
Let X be a smooth complex projective variety of dimension greater than or equal to 2, L an ample line bundle and k ≫ 0 an integer. We prove that a very generic global section of the twisted tangent sheaf gives rise to a foliation of X without any proper algebraic invariant subvarieties of nonzero dimension. As a corollary we obtain a dynamical characterization of ampleness for line bundles over smooth projective surfaces.
Tópico(s): Meromorphic and Entire Functions
2006 - De Gruyter | Journal für die reine und angewandte Mathematik (Crelles Journal)