Svetlana Hakobyan, Agustín Tortajada, Claire L. Harris, Santiago Rodrı́guez de Córdoba, B. Paul Morgan,
... precipitate disease in genetically susceptible individuals.18.Esparza-Gordillo J. Jorge E.G. Garrido C.A. et al.Insights ... normal individuals.11.Rodriguez de Cordoba S. Esparza-Gordillo J. Goicoechea de Jorge E. et al.The human complement factor H: ...
Tópico(s): Lysosomal Storage Disorders Research
2010 - Elsevier BV | Kidney International
Elena Goicoechea de Jorge, Matthew C. Pickering,
... individuals possessing all three risk factors.3.Esparza-Gordillo J. Jorge E.G. Garrido C.A. et al.Insights ... chromosome 1q32.4.Rodriguez de Cordoba S. Esparza-Gordillo J. Goicoechea de Jorge E. et al.The human complement factor H: ...
Tópico(s): Renal Diseases and Glomerulopathies
2010 - Elsevier BV | Kidney International
María Mendoza-Muñoz, José Carmelo Adsuar, Jorge Pérez‐Gómez, Laura Muñoz Bermejo, Miguel Ángel García-Gordillo, Jorge Carlos‐Vivas,
Background and objectives: Childhood obesity is one of the main public health issues facing advanced societies. The Spanish population presents 28.6% overweight or obese adolescents, and Extremadura, 22.3%. Physical fitness is considered one of the most important health markers and a common predictor of morbidity and mortality caused by cardiovascular diseases. Thus, fitness tests are needed for health monitoring, especially in overweight and obese adolescents. Therefore, this study aimed to explore ...
Tópico(s): Body Composition Measurement Techniques
2020 - Multidisciplinary Digital Publishing Institute | Medicina
Patricia Polero, Carmen Rebollo-Seco, José Carmelo Adsuar, Jorge Pérez‐Gómez, Jorge Rojo-Ramos, Fernando Manzano-Redondo, Miguel Ángel García-Gordillo, Jorge Carlos‐Vivas,
Regular practice of physical activity plays a fundamental role in preventing and treating cardiovascular diseases such as obesity, hypertension, diabetes, and metabolic syndrome. During the pandemic caused by COVID-19 and the lockdown established, people have reduced considerably their mobility and motor activity, which has led to an increase in unhealthy lifestyle habits, raising the risk of suffering from diseases. This paper consists of reviewing the existing scientific literature on recommendations ...
Tópico(s): COVID-19 and Mental Health
2020 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
María Mendoza-Muñoz, José Carmelo Adsuar, Jorge Pérez‐Gómez, Laura Muñoz Bermejo, Miguel Ángel García-Gordillo, Jorge Carlos‐Vivas,
Childhood obesity is one of the greatest public health problems facing advanced societies, and Spain is one of the countries with the highest incidence. There are many studies that monitor at the national level, but given the lack of specificity, lack of updating and scarcity of epidemiological data on overweight, obesity, physical condition and well-being of children and adolescents in Extremadura, it seems necessary to create a Well-being, Obesity and Motricity Observatory in Childhood and Youth ( ...
Tópico(s): Physical Activity and Health
2020 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Jorge Pérez‐Gómez, Helena Amigo‐Gamero, Daniel Collado‐Mateo, Sabina Barrios-Fernández, Laura Muñoz Bermejo, Miguel Ángel García-Gordillo, Jorge Carlos‐Vivas, José Carmelo Adsuar,
Accessible Summary What is known on the subject? Attention‐deficit/hyperactivity disorder (ADHD) is characterized by problems of inattention and impulsive hyperactivity in children. Equine‐assisted activities and therapies (EAATs) have been used as alternative non‐pharmacological intervention option in patients with ADHD. What does this paper adds to existing knowledge? Nowadays, more studies of high methodological quality are needed to determine whether EAAT is an effective intervention for the treatment ...
Tópico(s): Child and Adolescent Psychosocial and Emotional Development
2020 - Wiley | Journal of Psychiatric and Mental Health Nursing
Produção Nacional
Revisado por pares
Laura Muñoz Bermejo, José Carmelo Adsuar, Salvador Postigo Mota, Inés Casado-Verdejo, Claudia Mara de Melo-Tavares, Miguel Ángel García-Gordillo, Jorge Pérez‐Gómez, Jorge Carlos‐Vivas,
Elderly caregivers present increased physical and mental health problems. These factors can lead to a lack of autonomy and a need for social support. This study aims to analyse the relationships between perceived social support and mental health status in elderly caregivers aged 65 and older.a cross-sectional study based on data from the Spanish National Health Survey (ENSE-17) carried out on 7023 people. The study population was restricted to 431 caregivers aged ≥65 years. A study of the correlation ...
Tópico(s): Intergenerational Family Dynamics and Caregiving
2020 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Pere‐Joan Cardona, Sergi Gordillo, Jorge Dı́az, Gustavo Tapia, Isabel Amat, Ángeles Pallarés, Cristina Vilaplana, Aurelio Ariza, V. Ausina,
ABSTRACT We have used the murine model of aerosol-induced experimental tuberculosis to assess the effects of four clinical isolates and a reference strain of Mycobacterium tuberculosis on resistant C57BL/6 mice and susceptible DBA/2 mice. Histological studies and detection of 25 cytokines potentially involved in the infection were carried out. DBA/2 mice showed higher concentrations of bacilli in bronchoalveolar lavage fluid and lung tissue. Furthermore, these mice evidenced a larger granulomatous ...
Tópico(s): Pneumonia and Respiratory Infections
2003 - American Society for Microbiology | Infection and Immunity
Sandra Gordillo, Jorge Rabassa, Andrea Coronato,
As the Beagle Channel lies between the Atlantic and the Pacific oceans, this is a critical region for the interpretation of faunal distributions in the Magellan Region. This work proposes a paleoenvironmental interpretation of the Holocene, inferred from malacological data. The development of different local benthic paleocommunities during the mid-Holocene is associated with the diversity of habitats inside this channel. The analysis of records of Venus antigua and Ensis macha through time and their ...
Tópico(s): Isotope Analysis in Ecology
2008 - National Geology and Mining Service | Andean geology
Olga Gil, Evelyn Guirado, Sergi Gordillo, Jorge Dı́az, Gustavo Tapia, Cristina Vilaplana, Aurelio Ariza, V. Ausina, Pere‐Joan Cardona,
Low dose aerosol infection of C57BL/6 mice with a clinical strain of Mycobacterium tuberculosis (UTE 0335 R) induced intragranulomatous necrosis in pulmonary granulomas (INPG) at week 9 postinfection. Infection of different knockout (KO) mouse strains with UTE 0335 R induced INPG in all strains and established two histopathological patterns. The first pattern was seen in SCID mice and in mice with deleted α/β T receptor, TNF R1, IL-12, IFN-γ, or iNOS genes, and showed a massive INPG with a high granulomatous ...
Tópico(s): Tuberculosis Research and Epidemiology
2006 - Elsevier BV | Microbes and Infection
Jaime Salomón-Grajales, Gerardo V. Lugo-Moguel, Víctor R. Tinal-Gordillo, Jorge de La Cruz-Velázquez, Barry J. Beaty, Lars Eisen, Saúl Lozano‐Fuentes, Chester G. Moore, Julián E. García‐Rejón,
To the Editor: We collected Asian tiger mosquitoes, Aedes albopictus (Skuse), in Cancun in the Yucatan Peninsula of Mexico in September 2011. This mosquito is a nuisance biter of humans and a vector of numerous arboviruses, including those causing dengue, yellow fever, and chikungunya (1). Ae. albopictus mosquitoes, which are native to Southeast Asia, emerged in the continental United States in 1985 and thereafter spread rapidly across the southeastern United States and into northern Mexico (2,3). ...
Tópico(s): Malaria Research and Control
2012 - Centers for Disease Control and Prevention | Emerging infectious diseases
María Mendoza-Muñoz, Sabina Barrios-Fernández, José Carmelo Adsuar, Raquel Pastor-Cisneros, María Risco-Gil, Miguel Ángel García-Gordillo, Jorge Carlos‐Vivas,
Childhood obesity is a major health challenge in modern societies; therefore, prevention and management policies are needed. This study aims to establish the level of Physical Literacy (PL) in overweight and non-overweight children in Extremadura (Spain), analysing the potential differences between them and exploring their relationships with body composition.
Tópico(s): Health and Lifestyle Studies
2021 - Multidisciplinary Digital Publishing Institute | Biology
Laura Muñoz Bermejo, José Carmelo Adsuar, María Mendoza-Muñoz, Sabina Barrios-Fernández, Miguel Ángel García-Gordillo, Jorge Pérez‐Gómez, Jorge Carlos‐Vivas,
Functional independence in adults is conditioned by lower limb muscle strength. Thus, it seems important to assess lower limb strength using reliable and easy to reproduce measurements. The purpose of this study was to conduct a systematic review and meta-analysis to collect studies that examined the test-retest reliability of the Five Times Sit to Stand Test (FTSST) in adults. The search was conducted in PubMed, Web of Science, and Scopus databases, including all studies published up to 28 December ...
Tópico(s): Muscle activation and electromyography studies
2021 - Multidisciplinary Digital Publishing Institute | Biology
Maria Asuncion Abrera-Abeleda, Yiping Xu, Matthew C. Pickering, Richard J. Smith, Sanjeev Sethi,
... H dysfunction.4.Rodriguez de Cordoba S. Esparza-Gordillo J. Goicoechea de Jorge E. et al.The human complement factor H: ... the protein.4.Rodriguez de Cordoba S. Esparza-Gordillo J. Goicoechea de Jorge E. et al.The human complement factor H: ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2007 - Elsevier BV | Kidney International
Andrew P. Herbert, Dušan Uhrı́n, Malcolm Lyon, Michael K. Pangburn, Paul N. Barlow,
... is triggered by a range of factors (14Esparza-Gordillo J. Goicoechea de Jorge E. Buil A. Carreras Berges L. Lopez-Trascasa ... that appear to further enhance disease susceptibility (14Esparza-Gordillo J. Goicoechea de Jorge E. Buil A. Carreras Berges L. Lopez-Trascasa ...
Tópico(s): Blood groups and transfusion
2006 - Elsevier BV | Journal of Biological Chemistry
A Urban, Elena B. Volokhina, Anna Felberg, Grzegorz Stasiłojć, Anna M. Blom, Ilse Jongerius, Lambertus P. van den Heuvel, Marcel Thiel, Stanisław Ołdziej, Emilia Arjona, Santiago Rodrı́guez de Córdoba, Marcin Okrój,
... 1844-1859Crossref PubMed Scopus (698) Google Scholar, E16Esparza-Gordillo J. Goicoechea de Jorge E. Buil A. Carreras Berges L. Lopez-Trascasa ...
Tópico(s): Platelet Disorders and Treatments
2020 - Elsevier BV | Journal of Allergy and Clinical Immunology
Santiago Redondo, Emilio Muñoz Ruiz, Antonio Gordillo‐Moscoso, Jorge Navarro‐Dorado, Marta Ramajo, Esther Álvarez-Rodríguez, Fernando Reguillo, Manuel Carnero, Marta Casado, Teresa Tejerina,
Inflammation is a common feature in cardiovascular diseases, including diabetes mellitus. In addition to the well-known inflammatory role of cyclo-oxygenase-2 (COX-2), this protein has also been implicated in apoptosis resistance in tumour cells. Vascular smooth muscle cells (VSMC) from diabetic patients are also resistant to apoptosis because of an increased abundance of B cell lymphoma 2 protein (BCL2). In this work, we investigated whether overproduction of COX-2 was involved in the resistance to ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
2010 - Springer Science+Business Media | Diabetologia
Bárbara Gordillo-Román, Jorge Camacho-Ruiz, Marı́a A. Bucio, Pedro Joseph‐Nathan,
The use of vibrational circular dichroism spectroscopy for the chiral recognition of the two epimers of 6-cedrol, tricyclic sesquiterpenes, which contains oxygen as the heaviest atom, is shown. Bands in the 1500-850 cm(-1) region of the spectra were analyzed to calculate the anisotropy factors (g), which provided the regions of maximum circular dichroism effect for each epimer.
Tópico(s): Phytochemistry and Biological Activities
2011 - Wiley | Chirality
Jorge Esparza-Gordillo, Elena Goicoechea de Jorge, Cynthia Abarrategui Garrido, L Carreras, Margarita López‐Trascasa, Pilar Sánchez‐Corral, S DECORDOBA,
Mutations in the complement regulators factor H, membrane cofactor protein (MCP), and factor I are associated with atypical hemolytic uremic syndrome (aHUS, MIM 235400), suggesting that the disease develops as a consequence of the inefficient protection of the renal endothelium from damage by the complement system. Incomplete penetrance of the disease in individuals carrying these mutations is, however, relatively frequent. Here, we report the identification of a large, multiple affected aHUS pedigree ...
Tópico(s): Renal Diseases and Glomerulopathies
2006 - Elsevier BV | Molecular Immunology
Jorge Esparza-Gordillo, Elena Goicoechea de Jorge, Alfonso Buil, Luis Carreras Berges, Margarita López‐Trascasa, Pilar Sánchez‐Corral, Santiago Rodrı́guez de Córdoba,
Tópico(s): Erythrocyte Function and Pathophysiology
2005 - Oxford University Press | Human Molecular Genetics
Jorge Esparza-Gordillo, Elena Goicoechea de Jorge, Alfonso Buil, Luis Carreras Berges, Margarita López‐Trascasa, Pilar Sánchez‐Corral, Santiago Rodrı́guez de Córdoba,
The efficiency of the complement system as an innate immune defense mechanism depends on a fine control that restricts its action to pathogens and prevents non-specific damage to host tissues. Genetic and functional analyses have shown that this critical control of complement activation may be impaired in atypical hemolytic uremic syndrome (aHUS) patients. Mutations in HF1 , MCP or FI have been found in aHUS patients, but incomplete penetrance of the disease in individuals carrying these mutations ...
Tópico(s): Blood groups and transfusion
2005 - Oxford University Press | Human Molecular Genetics
S RODRIGUEZDECORDOBA, Jorge Esparza-Gordillo, Elena Goicoechea de Jorge, Margarita López‐Trascasa, Pilar Sánchez‐Corral,
Factor H is an essential regulatory protein that plays a critical role in the homeostasis of the complement system in plasma and in the protection of bystander host cells and tissues from damage by complement activation. Genetic and structural data generated during recent years have been instrumental to delineate the functional domains responsible for these regulatory activities in factor H, which is helping to understand the molecular basis underlying the different pathologies associated to factor ...
Tópico(s): Erythrocyte Function and Pathophysiology
2004 - Elsevier BV | Molecular Immunology
Ángel J. Gordillo‐Rivero, Jorge García‐Moreno, António Jordán, Lorena M. Zavala, Fernando Martins,
Abstract Although fire‐induced soil water repellency (SWR) and its effects on soil hydrology and geomorphology have been studied in detail, very few studies have considered the effect of rock fragments resting on the soil surface or partly embedded in soil. In this research, we have studied the effect of rock fragments on the strength and spatial distribution of fire‐induced SWR at different fire severities. A fire‐affected area was selected for this experiment and classified into different zones ...
Tópico(s): Landslides and related hazards
2013 - Wiley | Hydrological Processes
... Sonia Romero-Romero, Juan Bueno, J. Ignacio González-Gordillo, Xabier Irigoien, Jorge Sostres, Antonio Bode, Carmen Mompeán, Mariluz Fernández Puelles, ...
Tópico(s): Marine Biology and Ecology Research
2001 - University of Chicago Press | The American Naturalist
... Sonia Romero-Romero, Juan Bueno, J. Ignacio González-Gordillo, Xabier Irigoien, Jorge Sostres, Antonio Bode, Carmen Mompeán, Mariluz Fernández Puelles, ...
Tópico(s): Marine Biology and Ecology Research
2001 - University of Chicago Press | The American Naturalist
António Jordán, Lorena M. Zavala, Arturo José Pascual Granged, Ángel J. Gordillo‐Rivero, Jorge García‐Moreno, Paulo Pereira, Gema Bárcenas-Moreno, Reyes de Celis, Elisabeth Jiménez-Compán, Nancy Alanís,
Although the impact of ash on the hydrological and erosive response of burned soils has been studied in the last years, the effect of ash wettability on particle detachment by splash erosion has been rarely studied. In this research, we have studied the effect of wettable and water-repellent ash on the intensity of splash erosion after a prescribed burn in a Mediterranean shrubland. Runoff rates from wettable and water-repellent ash layers were also studied by rainfall simulation experiments (6 mm ...
Tópico(s): Aeolian processes and effects
2015 - Elsevier BV | The Science of The Total Environment
António Jordán, Ángel J. Gordillo‐Rivero, Jorge García‐Moreno, Lorena M. Zavala, Arturo José Pascual Granged, J. Gil, Helena M. Neto-Paixão,
Tópico(s): Plant Water Relations and Carbon Dynamics
2014 - Elsevier BV | CATENA
Adrián Domínguez-Domínguez, Ismael Martínez‐Guardado, Francisco Javier Domínguez‐Muñoz, Sabina Barrios-Fernández, Jesús Morenas Martín, Miguel Ángel García-Gordillo, Jorge Carlos‐Vivas,
Type 1 Diabetes Mellitus (T1D) is a chronic autoimmune disease characterized by the selective destruction of the beta cells of the pancreas causing an absolute deficiency of insulin for life. This pathology carries associated risks so that it is essential to measure Health-Related Quality of Life (HRQoL) in this population. The aim was to analyse associations between the level of physical activity and HRQoL in people with T1D. The sample consisted of 172 participants with T1D diagnoses, between 18 ...
Tópico(s): Diabetes Management and Education
2021 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Li Zhu, Weiyi Guo, Sufang Shi, Lijun Liu, Jicheng Lv, Nicholas Medjeral‐Thomas, Hannah J. Lomax-Browne, Matthew C. Pickering, Hong Zhang,
... C3b amplification loop.7Rodríguez de Córdoba S. Esparza-Gordillo J. Goicoechea de Jorge E. et al.The human complement factor H: ...
Tópico(s): Chronic Kidney Disease and Diabetes
2018 - Elsevier BV | Kidney International
Delu Song, Yoshiyasu Ueda, Rupak Bhuyan, Imran Mohammed, Takashi Miwa, Damodar Gullipali, Hangsoo Kim, Lin Zhou, Ying Song, Hannah Schultz, Albert Bargoud, Joshua L. Dunaief, Wen‐Chao Song,
... 204) Google Scholar, 7Rodríguez de Córdoba S. Esparza-Gordillo J. Goicoechea de Jorge E. Lopez-Trascasa M. Sánchez-Corral P. The ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2019 - Elsevier BV | American Journal Of Pathology