Filipa Guerreiro, Jorge F. Pontes, Ana M. Rosa da Costa, Ana Grenha,
Spray-drying is proposed in this work as the technique to produce konjac glucomannan microparticles aimed at an application in lung tuberculosis therapy. Microparticles were developed to provide direct lung delivery of an association of two first-line antitubercular drugs, isoniazid and rifabutin, by inhalation. Mannitol or leucine were incorporated as spray-drying excipients to verify their effect on the final properties of drug-loaded konjac glucomannan microparticles. The obtained results indicate ...
Tópico(s): Drug Solubulity and Delivery Systems
2018 - Elsevier BV | Powder Technology
João Guerreiro, Jorge Proença, João Gomes Ferreira, António Sousa Gago,
This article presents the results of an extensive experimental programme investigating the structural performance for in-plane loads of old masonry walls strengthened using a specific technique that consisted of applying a CFRP mesh embedded within a shotcreted render. In this article the expression old masonry refers to rubble stone masonry with lime-based mortar but it is believed that the strengthening technique can also be applied to other types of old masonry (e.g. solid or almost solid clay ...
Tópico(s): Structural Behavior of Reinforced Concrete
2018 - Elsevier BV | Composites Part B Engineering
Blanca Salinas‐Roca, Adriana Guerreiro, Jorge Welti‐Chanes, M. D. Carlos Antunes, Olga Martín‐Belloso,
Summary This study was aimed at evaluating the effect of coatings with alginate (AL), pectin (PE), carboxymethyl cellulose (CMC) or chitosan (CH) on microbial stability, physicochemical attributes, total phenolics and carotenoids content, antioxidant capacity and sensory properties of fresh‐cut mango during 14 days at 4 ± 1 °C. Coated fresh‐cut mango kept microbial counts below 6 logs CFU g −1 , being CH‐coated fresh‐cut mango those that exhibited the lowest microbial counts (1 log CFU g −1 ) along entire storage. ...
Tópico(s): Phytochemicals and Antioxidant Activities
2017 - Wiley | International Journal of Food Science & Technology
Cármen Júlia Del Rei Villa Flor, Caroline Ferreira Guerreiro, Jorge Luís Motta dos Anjos,
Introdução: O virús Zika (ZIKAV) no Brasil foi identificado no início de 2015, concomitantemente houve um aumento de casos de microcefalia, sendo 1.248 novos casos, representando um salto de vinte vezes em relação aos últimos anos. Objetivo: Avaliar o desenvolvimento neuropsicomotor (DNPM) em portadores de microcefalia pelo ZIKAV. MATERIAIS e Métodos: Pesquisa observacional, de corte transversal, com análise descritiva, através da revisão de dados em prontuários com a amostra composta por 22 lactentes ...
Tópico(s): Mosquito-borne diseases and control
2017 - ESCOLA BAHIANA DE MEDICINA E SAÚDE PÚBLICA | Revista Pesquisa em Fisioterapia
Sílvia A. Sousa, Joana R. Feliciano, Tiago Pita, Soraia Guerreiro, Jorge H. Leitão,
Burkholderia cepacia complex (Bcc) bacteria emerged as opportunistic pathogens in cystic fibrosis and immunocompromised patients. Their eradication is very difficult due to the high level of intrinsic resistance to clinically relevant antibiotics. Bcc bacteria have large and complex genomes, composed of two to four replicons, with variable numbers of insertion sequences. The complexity of Bcc genomes confers a high genomic plasticity to these bacteria, allowing their adaptation and survival to diverse ...
Tópico(s): Plant Pathogenic Bacteria Studies
2017 - Multidisciplinary Digital Publishing Institute | Genes
João M. S. Cardoso, Adelino M. Galvão, Soraia I. Guerreiro, Jorge H. Leitão, Ana C.M. Suárez, M. Fernanda N. N. Carvalho,
[Ag(NO 3 )(OC 10 H 14 NC 6 H 4 NC 10 H 14 O)] is the first bi-camphor silver coordination polymer structurally characterized. It displays bactericidal activity against Gram-negative and Gram-positive strains comparable to drugs in use.
Tópico(s): Organometallic Compounds Synthesis and Characterization
2016 - Royal Society of Chemistry | Dalton Transactions
Patrícia A. G. C. Silva, Ana Guerreiro, Jorge M. Santos, Joanna A. M. Braks, Chris J. Janse, Gunnar R. Mair,
UIS4 is a key protein component of the host-parasite interface in the liver stage of the rodent malaria parasite Plasmodium berghei and required for parasite survival after invasion. In the infectious sporozoite, UIS4 protein has variably been shown to be translated but also been reported to be translationally repressed. Here we show that uis4 mRNA translation is regulated by the P. berghei RNA binding protein Pumilio-2 (PbPuf2 or Puf2 from here on forward) in infectious salivary gland sporozoites ...
Tópico(s): Insect Resistance and Genetics
2016 - Public Library of Science | PLoS ONE
Bruno M. Guerreiro, Jorge Silva, João Carlos Lima, Maria A.M. Reis, Filomena Freitas,
Reactive oxygen species (ROS) are dangerous sources of macromolecular damage. While most derive from mitochondrial oxidative phosphorylation, their production can be triggered by exogenous stresses, surpassing the extinction capacity of intrinsic antioxidant defense systems of cells. Here, we report the antioxidant activity of FucoPol, a fucose-rich polyanionic polysaccharide produced by
Tópico(s): Polysaccharides and Plant Cell Walls
2021 - Multidisciplinary Digital Publishing Institute | Polymers
João Guerreiro, Jorge Proença, João Gomes Ferreira, António Sousa Gago,
This paper presents part of the results of an experimental study undertaken to develop a structural strengthening technique for old masonry buildings. The technique consisted of external reinforcement with a CFRP (Carbon Fibre Reinforced Polymer) reinforced render. CFRP reinforced render is an innovative seismic structural strengthening material for the structural masonry walls of old buildings. It consists of a non-cementitious mortar reinforced with a carbon fibre mesh and is applied to one or ...
Tópico(s): Innovative concrete reinforcement materials
2017 - Elsevier BV | Construction and Building Materials
Hugo Nicolau, Tiago Guerreiro, Joaquim Jorge, Daniel Gonçalves,
Tópico(s): Assistive Technology in Communication and Mobility
2013 - Springer Science+Business Media | Universal Access in the Information Society
Produção Nacional
Revisado por pares
Pedro Fernando da Costa Vasconcelos, José Wellington Oliveira Lima, Amélia P. A. Travassos da Rosa, Maria J. Timbó, Elizabeth Salbé Travassos da Rosa, Hascalon R. Lima, Sueli Guerreiro Rodrigues, Jorge Fernando Soares Travassos da Rosa,
OBJETIVO: Seguindo-se à epidemia de dengue (DEN), em 1994, em Fortaleza, Ceará, causada pelo sorotipo 2 (DEN-2), realizou-se inquérito soro-epidemiológico aleatório para avaliar e dimensionar o impacto da mesma e a prevalência do dengue por distrito sanitário. MÉTODO: Foi aplicado questionário contendo informações gerais, condições socio-econômicas, informações sobre o quadro clínico e tempo de doença. A amostra foi calculada para estimar uma prevalência de 20%, com erro relativo de 10%, e intervalo ...
Tópico(s): Leptospirosis research and findings
1998 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Joana Nogueira, Sandra Freitas, Diana Duro, Miguel Tábuas‐Pereira, Manuela Guerreiro, Jorge Almeida, Isabel Santana,
The Alzheimer's Disease Assessment Scale - Cognitive Subscale is a brief battery developed to assess cognitive functioning in Alzheimer's disease that encompasses the core characteristics of cognitive decline (e.g. memory, language, praxis, constructive ability and orientation). The early detection, as well as the monitoring of cognitive decline along disease progression, is extremely important in clinical care and interventional research. The main goals of the present study were to analyze the psychometric ...
Tópico(s): Dementia and Cognitive Impairment Research
2018 - Ordem dos Médicos | Acta Médica Portuguesa
Produção Nacional
Revisado por pares
Leandro Pio de Sousa, Oliveiro Guerreiro Filho, Jorge Maurı́cio Costa Mondego,
Coffee is one of the most important commodities in the global market. Of the 130 species of Coffea, only Coffea arabica and Coffea canephora are actually cultivated on a large scale. Despite the economic and social importance of coffee, little research has been done on the coffee tree microbiome. To assess the structure and function of the rhizosphere microbiome, we performed a deep shotgun metagenomic sequencing of the rhizospheres of five different species, C. arabica, C. canephora, Coffea stenophylla, ...
Tópico(s): Plant tissue culture and regeneration
2022 - American Society for Microbiology | Microbiology Spectrum
Produção Nacional
Revisado por pares
Gerusa R. S. Cavalcante, Beatriz Meireles Barguil, Willie Anderson dos Santos Vieira, Waléria Guerreiro Lima, Sami Jorge Michereff, Vinson P. Doyle, Marcos Paz Saraiva Câmara,
Anthracnose is one of the most important diseases of lima bean in Brazil. Previously, the disease was attributed exclusively to Colletotrichum truncatum. Therefore, this work aimed to characterize the diversity, prevalence, and virulence of Colletotrichum spp. associated with anthracnose in lima bean in Brazil. Here, we report the species C. truncatum, C. brevisporum, C. lobatum, C. plurivorum, and C. musicola in association with anthracnose of lima bean. All species were pathogenic to lima bean. ...
Tópico(s): Plant Pathogenic Bacteria Studies
2019 - American Phytopathological Society | Plant Disease
Produção Nacional
Revisado por pares
Josiene Silva Veloso, Marcos Paz Saraiva Câmara, Waléria Guerreiro Lima, Sami Jorge Michereff, Vinson P. Doyle,
Anthracnose is one of the most important plant diseases globally, occurring on a wide range of cultivated and wild host species. This study aimed to identify the Colletotrichum species associated with cashew anthracnose in Brazil, determine their phylogenetic relationships and geographical distribution, and provide some insight into the factors that may be influencing community composition. Colletotrichum isolates collected from symptomatic leaves, stems, inflorescences, and fruit of cultivated ...
Tópico(s): Yeasts and Rust Fungi Studies
2018 - Elsevier BV | Fungal Biology
Produção Nacional
Revisado por pares
Adriana Roseclér Alcará, Ivone Guerreiro Di Chiara, Jorge Luis Rodrigues, Maria Inês Tomaél, Valéria Cristina Heckler Piedade,
O compartilhamento da informação e do conhecimento é essencial para a construção de novos conhecimentos, porém esse processo pode ser influenciado por diferentes fatores. Este artigo apresenta os resultados de uma pesquisa sobre o compartilhamento da informação, do conhecimento e da experiência no ambiente de pesquisa e desenvolvimento (P&D). Os dados coletados, por meio de entrevistas, foram analisados a partir da técnica análise de conteúdo. Entre os resultados estão os principais fatores que ...
Tópico(s): Innovation and Knowledge Management
2009 - Universidade Federal de Minas Gerais, Escola de Ciência da Informação | Perspectivas em Ciência da Informação
Luis Vargas‐Chacoff, Francisco Dann, Kurt Paschke, R. Oyarzún, Daniela Nualart, D. Martínez, Jonathan M. Wilson, Pedro M. Guerreiro, Jorge M. Navarro,
Abstract Global warming is having a significant impact around the world, modifying environmental conditions in many areas, including in zones that have been thermally stable for thousands of years, such as Antarctica. Stenothermal sedentary intertidal fish species may suffer due to warming, notably if this causes water freshening from increased freshwater inputs. Acute decreases in salinity, from 33 down to 5, were used to assess osmotic responses to environmental salinity fluctuations in Antarctic ...
Tópico(s): Ocean Acidification Effects and Responses
2021 - Wiley | Journal of Fish Biology
Yilian M Pérez, Ana Gama, Ana Rita Pedro, Maria João Leote Carvalho, Ana Guerreiro, Vera Duarte, Jorge Quintas, Pedro Aguiar, Inês Keygnaert, Sónia Dias,
Lockdown, as a measure implemented to combat the coronavirus disease 2019 (COVID-19) pandemic, left many domestic violence (DV) victims trapped with their abusers. This study intends to explore the links between perceived stress, substance use and socio-demographic factors with DV experiences during COVID-19 pandemic in Portugal.A cross-sectional study was carried out on a sample of 1062 participants over 16 years old, residing in Portugal. Data were collected through an online survey conducted between ...
Tópico(s): Child Abuse and Trauma
2022 - Oxford University Press | Journal of Public Health
Hugo Pinto, Carla Nogueira, Jorge André Guerreiro, Fábio Ferrentini Sampaio,
The state is facing turbulent times. Financial and economic turmoil, growing inequalities, disinvestment in public and social services, and political disenchantment are but a few problems that contemporary society is facing, while traditional policies are failing to deliver the desired results. Social innovation is a possible approach to deal with emergent social needs. Research and policy experimentation on social innovation increased in the last decade, but many questions remain open. One key ...
Tópico(s): Innovative Approaches in Technology and Social Development
2021 - Multidisciplinary Digital Publishing Institute | World
Ana Gama, Ana Rita Pedro, Maria João Leote Carvalho, Ana Esteves Guerreiro, Vera Duarte, Jorge Quintas, Andreia Matias, Inês Keygnaert, Sónia Dias,
The measures implemented to combat the COVID-19 pandemic led populations to confinement at home, with increased risk of domestic violence due to extended shared time between victims and offenders. Evidence on domestic violence in times of pandemic is lacking. This study examines the occurrence of domestic violence, associated factors and help seeking during the COVID-19 pandemic. An online survey was conducted in Portugal between April and October 2020 by NOVA National School of Public Health. The ...
Tópico(s): Sexual Assault and Victimization Studies
2020 - Karger Publishers | Portuguese Journal of Public Health
R. S. Rodrigues Ribeiro, Pabitra Dahal, Ariel Guerreiro, P. A. S. Jorge, Jaime Viegas,
The development of economical optical devices with a reduced footprint foreseeing manipulation, sorting and detection of single cells and other micro particles have been encouraged by cellular biology requirements. Nonetheless, researchers are still ambitious for advances in this field. This paper presents Fresnel zone and phase plates fabricated on mode expanded optical fibres for optical trapping. The diffractive structures were fabricated using focused ion beam milling. The zone plates presented ...
Tópico(s): Near-Field Optical Microscopy
2017 - Nature Portfolio | Scientific Reports
R. S. Rodrigues Ribeiro, Pabitra Dahal, Ariel Guerreiro, P. A. S. Jorge, Jaime Viegas,
This Letter reports a new method for the generation of optical vortices using a micropatterned optical fiber tip. Here, a spiral phase plate (2π phase shift) is micromachined on the tip of an optical fiber using a focused ion beam. This is a high resolution method that allows milling the fibers with nanoscale resolution. The plate acts as a beam tailoring system, transforming the fundamental guided mode, specifically a Gaussian mode, into the Laguerre-Gaussian mode (LG01), which carries orbital angular ...
Tópico(s): Plasmonic and Surface Plasmon Research
2016 - Optica Publishing Group | Optics Letters
R. S. Rodrigues Ribeiro, Raquel B. Queirós, Olivier Soppera, Ariel Guerreiro, P. A. S. Jorge,
In this work the use of guided wave photo-polymerization for the fabrication of novel polymeric micro tips for optical trapping is demonstrated. It is shown that the selective excitation of linear polarized modes, during the fabrication process, has a direct impact on the shape of the resulting micro structures. Tips are fabricated with modes LP02 and LP21 and their shapes and output intensity distribution are compared. The application of the micro structures as optical tweezers is demonstrated ...
Tópico(s): Near-Field Optical Microscopy
2015 - Multidisciplinary Digital Publishing Institute | Photonics
Nunzio Cennamo, L. Coelho, D F N Santos, J. M. Baptista, Ariel Guerreiro, P. A. S. Jorge, Luigi Zeni,
In this paper, we present the numerical and the experimental results of a new low cost surface plasmon resonance sensor configuration. It is based on a plasmonic sensor platform and an efficient higher order modes filtering in plastic multimode fibers, exploiting a tapered plastic optical fiber at the output of the sensor system. The experimental results have demonstrated that the tapered filter positioned after the sensor system improves the performances in terms of refractive index range and depth ...
Tópico(s): Plasmonic and Surface Plasmon Research
2015 - IEEE Sensors Council | IEEE Sensors Journal
R. S. Rodrigues Ribeiro, Olivier Soppera, Abel Oliva, Ariel Guerreiro, P. A. S. Jorge,
In the last few decades, optical trapping has played an unique role concerning contactless trapping and manipulation of biological specimens. More recently, optical fiber tweezers (OFTs) are emerging as a desirable alternative to bulk optical systems. In this paper, an overview of the state of the art of OFTs is presented, focusing on the main fabrication methods, their features and main achievements. In addition, new OFTs fabricated by guided wave photo polymerization are reported. Their theoretical ...
Tópico(s): Plant Surface Properties and Treatments
2015 - Institute of Electrical and Electronics Engineers | Journal of Lightwave Technology
Ana Guerreiro, Elena Deligianni, Jorge M. Santos, Patrícia A. G. C. Silva, Christos Louis, Arnab Pain, Chris J. Janse, Blandine Franke–Fayard, Céline Carret, Inga Sidén‐Kiamos, Gunnar R. Mair,
Following fertilization, the early proteomes of metazoans are defined by the translation of stored but repressed transcripts; further embryonic development relies on de novo transcription of the zygotic genome. During sexual development of Plasmodium berghei, a rodent model for human malaria species including P. falciparum, the stability of repressed mRNAs requires the translational repressors DOZI and CITH. When these repressors are absent, Plasmodium zygote development and transmission to the ...
Tópico(s): Trypanosoma species research and implications
2014 - BioMed Central | Genome biology
Produção Nacional
Daniela Couto Guerreiro‐Casanova, Soely Aparecida Jorge Polydoro,
Autoeficácia na formação superior é entendida como a crença de um estudante em sua capacidade de organizar e executar cursos de ações requeridas para produzir certas realizações referentes aos aspectos compreendidos pelas tarefas acadêmicas pertinentes ao ensino superior. Com o objetivo de comparar a autoeficácia na formação superior entre o primeiro e o segundo períodos letivos, realizou-se esta pesquisa com 189 ingressantes em Letras, Matemática, Administração e Tecnologia da Informação de uma ...
Tópico(s): Education, Achievement, and Giftedness
2011 - Conselho Federal de Psicologia | Psicologia Ciência e Profissão
Gabriel Bernardo, M. Alexandra Esteves, Ana M. G. Guerreiro, Bárbara Gigante, Jorge Morgado,
Novel electroluminescent materials combining three functionalities were used as active layers in light-emitting diodes. These functionalities are brought about by the presence of three moieties: diphenylstylbeneamines, for hole transport, quinoxaline, for electron-transport, and a dehydroabietic acid methyl ester, to prevent crystallisation. The devices prepared with these materials and with magnesium cathodes show efficiencies up to 0.03 cd/A, which is about one order of magnitude higher than the ...
Tópico(s): Synthesis and Biological Evaluation
2008 - Elsevier BV | Optical Materials
Bruno M. Guerreiro, Jorge Silva, Cristiana A.V. Torres, Vítor D. Alves, João Carlos Lima, Maria A.M. Reis, Filomena Freitas,
This study reports the performance of the polysaccharide FucoPol as an enhancer of cryoprotective formulations. FucoPol at a concentration of 0.25% (w/v) was added to several normothermic Dulbecco-derived solutions and hypothermic Euro-Collins, Custodiol-HTK, and Unisol-CV media, substituting some constituents in the latter class to develop FucoPol-based formulations that were tested for their ability to cryopreserve Vero cells. Supplementation yielded post-thaw cell recovery enhancements of at least ...
Tópico(s): 3D Printing in Biomedical Research
2021 - American Chemical Society | ACS Applied Bio Materials
Produção Nacional
Revisado por pares
Marilúcia Reis dos Santos, Caroline Ferreira Guerreiro, Jorge Luís Motta dos Anjos, Cássio Magalhães da Silva e Silva,
Pacientes críticos internados na unidade de terapia intensiva (UTI) comumente apresentam declínio do estado funcional, sendo o tempo de permanência na ventilação mecânica invasiva (VMI) o fator de maior importância relacionado ao comprometimento do desempenho físico. Objetivo: Investigar a correlação da evolução do estado funcional entre a admissão e a alta com o tempo de VMI relacionada a mobilidade. Metodo: Trata-se de um estudo observacional, de delineamento transversal, realizado nas UTI's de ...
Tópico(s): Family and Patient Care in Intensive Care Units
2019 - | Acta Fisiátrica