Susana Gámez Vivaldo, Luis Jorge García-Márquez, David Osorio Sarabia, José Luis Vázquez García, Fernando Constantino Casas,
The purpose of this work was to report the causes of mortality of eleven Olive Ridley Turtle (Lepidochelys olivacea) that arrived to the shore of Cuyutlan, C...
Tópico(s): Wildlife Conservation and Criminology Analyses
2009 - National Autonomous University of Mexico | Veterinaria
Enoc Cetina-Mancilla, Lilian I. Olvera, Jorge Balmaseda, Michael Förster, F. Alberto Ruiz‐Treviño, Jorge Cárdenas, Eduardo Vivaldo‐Lima, Mikhail G. Zolotukhin,
Synthesis of processable, aromatic pyridine-containing polymers has always been a great challenge.
Tópico(s): Synthesis and Properties of Aromatic Compounds
2020 - Royal Society of Chemistry | Polymer Chemistry

Luciana Romão, Fábio A. Mendes, Natália Martins Feitosa, Jane Faria, Juliana M. Coelho‐Aguiar, Jorge Marcondes de Souza, Vivaldo Moura‐Neto, José G. Abreu,
Connective-tissue growth factor (CTGF/CCN2) is a matricellular-secreted protein involved in complex processes such as wound healing, angiogenesis, fibrosis and metastasis, in the regulation of cell proliferation, migration and extracellular matrix remodeling. Glioblastoma (GBM) is the major malignant primary brain tumor and its adaptation to the central nervous system microenvironment requires the production and remodeling of the extracellular matrix. Previously, we published an in vitro approach ...
Tópico(s): TGF-β signaling in diseases
2013 - Public Library of Science | PLoS ONE

Anna Carolina Carvalho da Fonseca, Luciana Romão, Rackele Ferreira do Amaral, Suzana Assad Kahn, Denise S. Lobo, Sheila Cristina de Souza Martins, Jorge Marcondes de Souza, Vivaldo Moura‐Neto, Flávia Regina Souza Lima,
Microglial activation is a key event in the progression and infiltration of tumors. We have previously demonstrated that the co-chaperone stress inducible protein 1 (STI1), a cellular prion protein (PrPC) ligand, promotes glioblastoma (GBM) proliferation. In the present study, we examined the influence of microglial STI1 in the growth and invasion of the human glioblastoma cell line GBM95. We demonstrated that soluble factors secreted by microglia into the culture medium (microglia conditioned medium; ...
Tópico(s): Nuclear Receptors and Signaling
2011 - Elsevier BV | Neuroscience
Roberto López, Gerardo Villa-Sánchez, Israel Vivaldo, Cecilia Encarnación‐Gómez, V. H. Castrejón-Sánchez, A. Coyopol, Jorge Edmundo Mastache Mastache, César Leyva‐Porras,
The p-n junction is the fundamental form of an electronic semiconductor device. A p-CuO/n-ZnO heterojunction diode was formed by using thermal evaporation and thermal oxidation techniques. Cupric oxide (CuO) films of 300 µm in thickness were obtained by thermal oxidation of Cu foils. Zinc oxide (ZnO) films of 30 µm in thickness were prepared in two process steps: firstly, thermal evaporation of Zn at atmospheric pressure, and then thermal oxidation to Zn films. The p-CuO/n-ZnO heterojunction diode ...
Tópico(s): Gas Sensing Nanomaterials and Sensors
2021 - Elsevier BV | Results in Physics

André Quincozes‐Santos, Larissa Daniele Bobermin, Naithan Ludian Fernandes Costa, Natalie K. Thomaz, Rômulo Rodrigo de Souza Almeida, Walter O. Beys‐da‐Silva, Lucélia Santi, Rafael Lopes da Rosa, Daniela Capra, Juliana M. Coelho‐Aguiar, Marcos F. DosSantos, Manoela Heringer, Elizabeth Obino Cirne Lima, Jorge A. Guimarães, Lavínia Schüler‐Faccini, Carlos‐Alberto Gonçalves, Vivaldo Moura‐Neto, Diogo O. Souza,
Abstract Zika virus (ZIKV) is a strongly neurotropic flavivirus whose infection has been associated with microcephaly in neonates. However, clinical and experimental evidence indicate that ZIKV also affects the adult nervous system. In this regard, in vitro and in vivo studies have shown the ability of ZIKV to infect glial cells. In the central nervous system (CNS), glial cells are represented by astrocytes, microglia, and oligodendrocytes. In contrast, the peripheral nervous system (PNS) constitutes ...
Tópico(s): Viral Infections and Vectors
2023 - Wiley | Glia

Tércia Alves, Anna Carolina Carvalho da Fonseca, Sara S. Nunes, Aline Oliveira da Silva de Barros, Luiz Gustavo Dubois, Jane Faria, Suzana Assad Kahn, Nathan B. Viana, Jorge Marcondes de Souza, Chantal Legrand, Vivaldo Moura‐Neto, Verônica Morandi,
The extracellular matrix (ECM) contains important cues for tissue homeostasis and morphogenesis. The matricellular protein tenascin-C (TN-C) is overexpressed in remodeling tissues and cancer. In the present work, we studied the effect of different ECM—which exhibited a significant diversity in their TN-C content—in endothelial survival, proliferation and tubulogenic differentiation: autologous (endothelial) ECM devoid of TN-C, but bearing large amounts of FN; fibroblast ECM, bearing both high TN-C ...
Tópico(s): Cellular Mechanics and Interactions
2011 - Elsevier BV | Experimental Cell Research

Alexandre Martins Cunha, Fernanda S. Nascimento, Jane C. O. F. Amaral, Sandra König, Christina Maeda Takiya, Vivaldo Moura‐Neto, Eduardo Rocha, Jorge Marcondes de Souza,
Several animal experimental models have been used in the study of malignant gliomas. The objective of the study was to test the efficacy of a simple, reproducible and low cost animal model, using human cells of glioblastoma multiforme (GBM) xenotransplantated in subcutaneous tissue of Wistar rats, immunosuppressed with cyclosporin given by orogastric administration, controlled by nonimunosuppressed rats. The animals were sacrificed at weekly intervals and we have observed gradual growth of tumor ...
Tópico(s): Cancer Research and Treatments
2011 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria

Jane Faria, Luciana Romão, Sheila Cristina de Souza Martins, Tércia Alves, Fábio A. Mendes, Giselle Pinto de Faria, Rosenilde Hollanda, Christina Maeda Takiya, Leila Chimelli, Verônica Morandi, Jorge Marcondes de Souza, José G. Abreu, Vivaldo Moura‐Neto,
The harmonious development of the central nervous system depends on the interactions of the neuronal and glial cells. Extracellular matrix elements play important roles in these interactions, especially laminin produced by astrocytes, which has been shown to be a good substrate for neuron growth and axonal guidance. Glioblastomas are the most common subtypes of primary brain tumors and may be astrocytes in origin. As normal laminin-producing glial cells are the preferential substrate for neurons, ...
Tópico(s): Cell Adhesion Molecules Research
2006 - Elsevier BV | Differentiation

Celina García, Luiz Gustavo Dubois, Anna L. R. Xavier, Luiz Henrique Geraldo, Anna Carolina Carvalho da Fonseca, Ana Helena Pereira Correia, Fernanda Meirelles, Grasiella M. Ventura, Luciana Romão, Nathalie Henriques Silva Canêdo, Jorge Marcondes de Souza, João R.L. Menezes, Vivaldo Moura‐Neto, Fernanda Tovar‐Moll, Flávia Regina Souza Lima,
Glioblastoma (GBM) is the most common primary brain tumor and the most aggressive glial tumor. This tumor is highly heterogeneous, angiogenic, and insensitive to radio- and chemotherapy. Here we have investigated the progression of GBM produced by the injection of human GBM cells into the brain parenchyma of immunocompetent mice. Xenotransplanted animals were submitted to magnetic resonance imaging (MRI) and histopathological analyses. Our data show that two weeks after injection, the produced tumor ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2014 - BioMed Central | BMC Cancer
Rafael‐Aurelio Rodríguez‐Jiménez, Yesmin Panecatl‐Bernal, J. Carrillo-López, Miguel‐Ángel Méndez‐Rojas, Anabel Romero‐López, M. Pacio, Israel Vivaldo, A. Morales–Sánchez, R. Arce, Jorge Caram, Julio Villanueva‐Cab, J. Alvarado,
Abstract The influence of ethanolic extracts of three common plants ( Equisetum arvense, Syzygium aromaticum and Camellia sinensis ) on the morphology and size distribution of TiO 2 nanoparticles prepared using the sol‐gel method is presented. The phytochemicals extracted from the plants acted as surfactants, modifying the growth mechanism and stabilizing high‐quality small, quasi‐spherical, non‐aggregated TiO 2 nanoparticles with sizes in the range from 20–50 nm. The most satisfactory result was achieved ...
Tópico(s): Pigment Synthesis and Properties
2021 - Wiley | ChemistrySelect

Carla Pires Veríssimo, Juliana da Silva Nogueira Carvalho, Fábio Jorge Moreira da Silva, Loraine Campanati, Vivaldo Moura‐Neto, Juliana de Mattos Coelho‐Aguiar,
The enteric glia, a neural crest-derived cell type that composes the Enteric Nervous System, is involved in controlling gut functions, including motility, gut permeability, and neuronal communication. Moreover this glial cell could to give rise to new neurons. It is believed that enteric neurons are generated up to 21 days postnatally; however, adult gut cells with glial characteristics can give rise to new enteric neurons under certain conditions. The factors that activate this capability of enteric ...
Tópico(s): Gastrointestinal motility and disorders
2019 - Frontiers Media | Frontiers in Neuroscience

Suzana Assad Kahn, Deborah Biasoli, Celina García, Luiz Henrique Geraldo, Bruno Pontes, Morgana Sobrinho, Ana Carina Bon‐Frauches, Luciana Romão, Rossana C. Soletti, Fernando dos Santos Assunção, Fernanda Tovar‐Moll, Jorge Marcondes de Souza, Flávia Regina Souza Lima, Gregor Anderluh, Vivaldo Moura‐Neto,
Glioblastoma (GBM) is considered incurable due to its resistance to current cancer treatments. So far, all clinically available alternatives for treating GBM are limited, evoking the development of novel treatment strategies that can more effectively manage these tumors. Extensive effort is being dedicated to characterize the molecular basis of GBM resistance to chemotherapy and to explore novel therapeutic procedures that may improve overall survival. Cytolysins are toxins that form pores in target ...
Tópico(s): Marine Toxins and Detection Methods
2012 - Bentham Science Publishers | Current Topics in Medicinal Chemistry

Joana Balça-Silva, Diana Matias, Anália do Carmo, Luiz Gustavo Dubois, Ana Cristina Gonçalves, Henrique Girão, Nathalie Henriques Silva Canêdo, Ana Helena Pereira Correia, Jorge Marcondes de Souza, Ana Bela Sarmento‐Ribeiro, María Celeste Lopes, Vivaldo Moura‐Neto,
Glioblastoma (GBM) is a grade IV astrocytoma. GBM patients show resistance to chemotherapy such as temozolomide (TMZ), the gold standard treatment. In order to simulate the molecular mechanisms behind the different chemotherapeutic responses in GBM patients we compared the cellular heterogeneity and chemotherapeutic resistance mechanisms in different GBM cell lines. We isolated and characterized a human GBM cell line obtained from a GBM patient, named GBM11. We studied the GBM11 behaviour when treated ...
Tópico(s): DNA Repair Mechanisms
2017 - Elsevier BV | Oncology Reports

Tereza C.C. Silva, Giselle Pinto de Faria Lopes, Noélio de Jesus Menezes-Filho, Diêgo M. de Oliveira, Ezequiel Pereira, Bruno Penas Seara Pitanga, Rafael dos Santos Costa, Eudes da Silva Velozo, Songelí Menezes Freire, Jorge Clarêncio, Helena L. Borges, Stevens K. Rehen, Vivaldo Moura‐Neto, Sílvia Lima Costa,
Background: A glioblastoma is a primary CNS tumor that is more aggressive and lethal than other brain tumors. Its location, rapid proliferation, invasive growth, angiogenesis and immunosuppression are the main factors that limit its treatment, making it a major challenge to neuro-oncology. Objective: This study investigated the in vitro effects of the alkaloid dihydrochelerythrine (DHC), which is extracted from Zanthoxylum stelligerum, on the viability, proliferation, cell death and β-catenin, NFκB, ...
Tópico(s): Biological and pharmacological studies of plants
2018 - Bentham Science Publishers | Anti-Cancer Agents in Medicinal Chemistry
Jorge J. Hernández‐Meza, Gabriel Jaramillo‐Soto, Pedro R. García‐Morán, Joaquín Palacios‐Alquisira, Eduardo Vivaldo‐Lima,
Abstract Calculations of the polymerization rate and molecular weight development in the nitroxide‐mediated radical polymerization (NMRP) of styrene (STY), using hydroxyl‐TEMPO and dibenzoyl peroxide (BPO), and activated by microwave irradiation (MI), are presented. The calculations are based on a kinetic model developed in our group. Microwave activation is modeled by three approaches: microwave‐activated production of free radicals from monomer molecules, microwave‐enhanced thermal initiation, and ...
Tópico(s): Photopolymerization techniques and applications
2009 - Wiley | Macromolecular Reaction Engineering

Ravena Pereira do Nascimento, Balbino Lino dos Santos, Karina C. da Silva, Víctor Diógenes Amaral da Silva, Maria de Fátima Dias Costa, Jorge M. David, Juceni P. David, Vivaldo Moura‐Neto, Mona N. Oliveira, Henning Ulrich, Giselle Pinto de Faria Lopes, Sílvia Lima Costa,
Glioblastoma is the most lethal tumor of the central nervous system, presenting a very poor prognostic, with a survival around 16 months. The interaction of mesenchymal stem cells and tumor cells has been studied, showing a bias in their role favoring or going against aggressiveness. Natural products such as flavonoids have showed their anticancer properties and the synergic potential with the activation of microenvironment cells to inhibit tumor progression. Agathisflavone is a flavonoid studied ...
Tópico(s): Biological Activity of Diterpenoids and Biflavonoids
2020 - Wiley | Journal of Cellular Physiology

Lavínia Schüler‐Faccini, Paulo Michel Roehe, Eduardo R. Zimmer, André Quincozes‐Santos, Adriano Martimbianco de Assis, Elizabeth Obino Cirne Lima, Jorge Almeida Guimarães, César G. Victora, Vivaldo Moura‐Neto, Diogo O. Souza,
Tópico(s): Vector-Borne Animal Diseases
2017 - Springer Science+Business Media | Molecular Neurobiology

Vivaldo Gemaque De Almeida, Jorge Carlos Menezes Nascimento, Pablício Pereira Cardoso,
O transtorno bipolar é uma condição psiquiátrica crônica caracterizada por oscilações recorrentes de humor entre polos de mania/hipomania e depressão. O presente estudo objetivou realizar uma revisão integrativa da literatura recente sobre suas características, diagnóstico diferencial e tratamento medicamentoso e psicoterápico. Realizou-se busca nas bases PubMed e SciELO utilizando descritores controlados e termos livres. Foram incluídos 11 estudos, publicados entre 2021-2023, abordando aspectos ...
Tópico(s): Electroconvulsive Therapy Studies
2023 - | Revista Contemporânea
Adriana Chamú‐Muñoz, Oscar Hernández‐Meléndez, Martín G. Hernández-Luna, Jorge Alcaraz‐Cienfuegos, Eduardo Vivaldo‐Lima, Eduardo Bárzana,
Ethylene carbonate (EC) is selected as reagent and green solvent for the modification of corncob (CC), a lignocellulosic residue obtained from wet or dry milling processes during industrial and food applications of corn grains, as well as from ethanol production plants, using the following three reaction systems: (i) liquid phase (LP) and LP‐pressurized at moderate temperatures (85–175°C); (ii) solid phase at low temperatures (65–85 °C); and (iii) vapor phase at moderate temperatures (120–160 °C). Both the ...
Tópico(s): Lignin and Wood Chemistry
2015 - Wiley | Macromolecular Materials and Engineering
Mariângela Claudia Herrera Borges, Mariana Fernandes de Lima, Valdeneide Santos da Silva, Luiz Fidelis Barreira Júnior, João Rafael Ferraz, Eliane Aparecida de Oliveira Costa, Aguinaldo Alves de Paiva Júnior, Vivaldo Medeiros Santos, Jorge Luiz Fernandes da Silva, Anicarine Ribeiro Leão, Denise de Almeida, Amanda Juliane da Silva Branco,
Foi realizado uma pesquisa de revisão de estudo do conteúdo referente ao tema de termografia odontológica, com ajuda de artigos e pesquisas relacionadas a termografia infravermelha e sua grande importância na odontologia em específico.
Tópico(s): Infrared Thermography in Medicine
2018 - | Revista Remecs - Revista Multidisciplinar de Estudos Científicos em Saúde

Vivaldo Gemaque De Almeida, Jorge Carlos Menezes Nascimento, Pablício Pereira Cardoso,
O suicídio representa um grave problema de saúde pública em âmbito global, constituindo uma das principais causas de morte prematura, especialmente entre jovens. Considerando também as tentativas não fatais, fica evidente a necessidade de estratégias abrangentes de prevenção, enfocando os fatores de risco e o manejo adequado de indivíduos em risco. O presente estudo teve por objetivo explorar as principais estratégias para a prevenção do suicídio mediante revisão integrativa da literatura científica ...
Tópico(s): Suicide and Self-Harm Studies
2023 - | Revista Contemporânea

Vivaldo Gemaque De Almeida, Jorge Carlos Menezes Nascimento, Pablício Pereira Cardoso,
A ansiedade é um dos transtornos psiquiátricos mais prevalentes em crianças e adolescentes, acometendo de 10 a 20% dessa população segundo a maioria dos estudos. As manifestações clínicas incluem preocupação excessiva, medos intensos, evitação de situações sociais, irritabilidade, queixas somáticas e pensamentos negativos. O diagnóstico requer investigação cuidadosa e uso de instrumentos psicométricos validados para essa faixa etária. O tratamento multimodal envolve principalmente psicoterapia cognitivo- ...
Tópico(s): Youth, Drugs, and Violence
2023 - | Revista Contemporânea

Vivaldo Gemaque De Almeida, Jorge Carlos Menezes Nascimento, Pablício Pereira Cardoso,
A depressão é um importante problema de saúde pública entre idosos, com prevalência de 10-15% na comunidade e até 42% nos institucionalizados. Está associada a diversos fatores de risco biopsicossociais como doenças clínicas, declínio funcional e isolamento social. Quando não adequadamente tratada, leva a desfechos negativos como pior qualidade de vida, incapacidade e mortalidade aumentada. Este estudo objetivou explorar, por revisão de literatura, estratégias de prevenção e cuidado da depressão ...
Tópico(s): Youth, Drugs, and Violence
2023 - | Revista Contemporânea

Carla Pires Veríssimo, Lionete Gall Acosta Filha, Fábio Jorge Moreira da Silva, Harrison James Westgarth, Juliana De Mattos Coelho Aguiar, Bruno Pontes, Vivaldo Moura‐Neto, Parisa Gazerani, Marcos F. DosSantos,
Several studies have proved that glial cells, as well as neurons, play a role in pain pathophysiology. Most of these studies have focused on the contribution of central glial cells (e.g., microglia and astrocytes) to neuropathic pain. Likewise, some works have suggested that peripheral glial cells, particularly satellite glial cells (SGCs), and the crosstalk between these cells and the sensory neurons located in the peripheral ganglia, play a role in the phenomenon that leads to pain. Nonetheless, ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2022 - Caister Academic Press | Current Issues in Molecular Biology
Estefanía Sierra-Ibarra, Jorge Alcaraz‐Cienfuegos, Alejandra Vargas‐Tah, Alberto Rosas‐Aburto, Ángeles Valdivia-López, Martín G. Hernández-Luna, Eduardo Vivaldo‐Lima, Alfredo Martı́nez,
Teak wood residues were subjected to thermochemical pretreatment, enzymatic saccharification, and detoxification to obtain syrups with a high concentration of fermentable sugars for ethanol production with the ethanologenic Escherichia coli strain MS04. Teak is a hardwood, and thus a robust deconstructive pretreatment was applied followed by enzymatic saccharification. The resulting syrup contained 60 g l-1 glucose, 18 g l-1 xylose, 6 g l-1 acetate, less than 0.1 g l-1 of total furans, and 12 g ...
Tópico(s): Catalysis for Biomass Conversion
2021 - Springer Science+Business Media | Journal of Industrial Microbiology & Biotechnology
Miguel Ángel Vega‐Hernández, Alberto Rosas‐Aburto, Eduardo Vivaldo‐Lima, Humberto Vázquez‐Torres, Gema Susana Cano‐Díaz, Patricia Pérez‐Salinas, Martín G. Hernández-Luna, Jorge Alcaraz‐Cienfuegos, Mikhail G. Zolotukhin,
ABSTRACT A new approach for the production of polystyrene‐blue agave bagasse (BAB) composite materials is presented. In this approach, dried powdered raw BAB is press molded in the presence of a coupling agent based on glycidyl methacrylate (GMA), producing a hybrid material of poly(GMA) grafted onto BAB. The in situ reversible addition‐fragmentation chain transfer (RAFT) polymerization of styrene in presence of this poly(GMA)‐graft‐BAB hybrid material results in a reinforced composite material. These ...
Tópico(s): Advanced Cellulose Research Studies
2018 - Wiley | Journal of Applied Polymer Science

Suzana Assad Kahn, Deborah Biasoli, Celina García, Luiz Henrique Geraldo, Bruno Pontes, Morgana Sobrinho, Ana Carina Bon‐Frauches, Luciana Romão, Rossana C. Soletti, Fernando Assuncao, Fernanda Tovar‐Moll, Jorge de Souza, Flávia Regina Souza Lima, Gregor Anderluh, Vivaldo Moura‐Neto,
Glioblastoma (GBM) is considered incurable due to its resistance to current cancer treatments. So far, all clinically available alternatives for treating GBM are limited, evoking the development of novel treatment strategies that can more effectively manage these tumors. Extensive effort is being dedicated to characterize the molecular basis of GBM resistance to chemotherapy and to explore novel therapeutic procedures that may improve overall survival. Cytolysins are toxins that form pores in target ...
Tópico(s): Marine Invertebrate Physiology and Ecology
2013 - Bentham Science Publishers | Current Topics in Medicinal Chemistry
Miguel Ángel Vega‐Hernández, María Fernanda Munguía-Quintero, Alberto Rosas‐Aburto, Jorge Alcaraz‐Cienfuegos, María de los Ángeles Valdivia-López, Martín G. Hernández-Luna, Eduardo Vivaldo‐Lima,
Cellulose modified hydrogels can be produced directly from raw biopolymers in novel cellulose solvents such as NaOH/urea aqueous solution. The effect of cellulose characteristics on the synthesis of a cellulose-graft-(net-poly(acrylamide-co-acrylic acid)) and its performance as water absorbent/methylene blue dye removal material is analyzed. Three cellulose samples, one analytical grade and two obtained from teak wood sawdust with different pretreatments (one alkaline and the other, a novel one known ...
Tópico(s): Hydrogels: synthesis, properties, applications
2024 - Elsevier BV | International Journal of Biological Macromolecules
Débora Aparecida de Almeida, Eliana De Medeiros Marques, Júlio César Pires Assumpção, Jussara Nepomuceno de Andrade, Leidiane Rocha Scervino, Luiz Faustino dos Santos Maia, João Rafael Ferraz, Aguinaldo Alves de Paiva Júnior, Vivaldo Medeiros Santos, Luciana Takahashi Carvalho Ribeiro, Jorge Luiz Fernandes da Silva, Anicarine Ribeiro Leão, Denise De Almeida, Amanda Juliane da Silva Branco,
A Tomografia por Emissão de Pósitrons (PET/CT) é um exame de imagem da Medicina Nuclear que utiliza radionuclídeos que emitem um pósitron no momento da sua desintegração. Em 1896, foi descoberta a radioatividade natural dos sais de urânio por Henri Becquerel.
Tópico(s): Radiation Dose and Imaging
2018 - | Revista Remecs - Revista Multidisciplinar de Estudos Científicos em Saúde